(2R)-N-(3-carbamoylphenyl)-2-[3-[(5-methyl-6,7-dihydro-4H-[1,3]thiazolo[5,4-c]pyridin-2-yl)carbamoyl]phenyl]pyrrolidine-1-carboxamide;(2R)-N-(4-carbamoylphenyl)-2-[3-[(5-methyl-6,7-dihydro-4H-[1,3]thiazolo[5,4-c]pyridin-2-yl)carbamoyl]phenyl]pyrrolidine-1-carboxamide;3-[(2R)-1-(4-cyano-2,3-dihydroindole-1-carbonyl)pyrrolidin-2-yl]-N-(5-methyl-6,7-dihydro-4H-[1,3]thiazolo[5,4-c]pyridin-2-yl)benzamide;3-[(3R)-1-(4-cyanophenyl)pyrrolidin-3-yl]oxy-N-(5-methyl-6,7-dihydro-4H-[1,3]thiazolo[5,4-c]pyridin-2-yl)benzamide;N-(3-cyanophenyl)-2-[3-(1,2,3,4-tetrahydroisoquinolin-7-ylcarbamoyl)phenyl]pyrrolidine-1-carboxamide;N-(4-cyanophenyl)-2-[3-(1,2,3,4-tetrahydroisoquinolin-7-ylcarbamoyl)phenyl]pyrrolidine-1-carboxamide;3-[1-(3,4-dimethoxybenzoyl)pyrrolidin-2-yl]-N-(1,2,3,4-tetrahydroisoquinolin-7-yl)benzamide;N-[(6S)-6-(dimethylamino)-4,5,6,7-tetrahydro-1,3-benzothiazol-2-yl]-3-[(2R)-1-(4-methyl-2-pyridin-4-yl-1,3-thiazole-5-carbonyl)pyrrolidin-2-yl]benzamide

C220H226N42O20S6 — CID 159080512

IUPAC(2R)-N-(3-carbamoylphenyl)-2-[3-[(5-methyl-6,7-dihydro-4H-[1,3]thiazolo[5,4-c]pyridin-2-yl)carbamoyl]phenyl]pyrrolidine-1-carboxamide;(2R)-N-(4-carbamoylphenyl)-2-[3-[(5-methyl-6,7-dihydro-4H-[1,3]thiazolo[5,4-c]pyridin-2-yl)carbamoyl]phenyl]pyrrolidine-1-carboxamide;3-[(2R)-1-(4-cyano-2,3-dihydroindole-1-carbonyl)pyrrolidin-2-yl]-N-(5-methyl-6,7-dihydro-4H-[1,3]thiazolo[5,4-c]pyridin-2-yl)benzamide;3-[(3R)-1-(4-cyanophenyl)pyrrolidin-3-yl]oxy-N-(5-methyl-6,7-dihydro-4H-[1,3]thiazolo[5,4-c]pyridin-2-yl)benzamide;N-(3-cyanophenyl)-2-[3-(1,2,3,4-tetrahydroisoquinolin-7-ylcarbamoyl)phenyl]pyrrolidine-1-carboxamide;N-(4-cyanophenyl)-2-[3-(1,2,3,4-tetrahydroisoquinolin-7-ylcarbamoyl)phenyl]pyrrolidine-1-carboxamide;3-[1-(3,4-dimethoxybenzoyl)pyrrolidin-2-yl]-N-(1,2,3,4-tetrahydroisoquinolin-7-yl)benzamide;N-[(6S)-6-(dimethylamino)-4,5,6,7-tetrahydro-1,3-benzothiazol-2-yl]-3-[(2R)-1-(4-methyl-2-pyridin-4-yl-1,3-thiazole-5-carbonyl)pyrrolidin-2-yl]benzamide
SMILESCN1CCc2nc(NC(=O)c3cccc(O[C@@H]4CCN(c5ccc(C#N)cc5)C4)c3)sc2C1.CN1CCc2nc(NC(=O)c3cccc([C@H]4CCCN4C(=O)N4CCc5c(C#N)cccc54)c3)sc2C1.CN1CCc2nc(NC(=O)c3cccc([C@H]4CCCN4C(=O)Nc4ccc(C(N)=O)cc4)c3)sc2C1.CN1CCc2nc(NC(=O)c3cccc([C@H]4CCCN4C(=O)Nc4cccc(C(N)=O)c4)c3)sc2C1.COc1ccc(C(=O)N2CCCC2c2cccc(C(=O)Nc3ccc4c(c3)CNCC4)c2)cc1OC.Cc1nc(-c2ccncc2)sc1C(=O)N1CCC[C@@H]1c1cccc(C(=O)Nc2nc3c(s2)C[C@@H](N(C)C)CC3)c1.N#Cc1ccc(NC(=O)N2CCCC2c2cccc(C(=O)Nc3ccc4c(c3)CNCC4)c2)cc1.N#Cc1cccc(NC(=O)N2CCCC2c2cccc(C(=O)Nc3ccc4c(c3)CNCC4)c2)c1
InChIInChI=1S/C30H32N6O2S2.C29H31N3O4.C28H28N6O2S.2C28H27N5O2.2C26H28N6O3S.C25H25N5O2S/c1-18-26(40-28(32-18)19-11-13-31-14-12-19)29(38)36-15-5-8-24(36)20-6-4-7-21(16-20)27(37)34-30-33-23-10-9-22(35(2)3)17-25(23)39-30;1-35-26-11-9-22(17-27(26)36-2)29(34)32-14-4-7-25(32)20-5-3-6-21(15-20)28(33)31-24-10-8-19-12-13-30-18-23(19)16-24;1-32-13-11-22-25(17-32)37-27(30-22)31-26(35)19-6-2-5-18(15-19)23-9-4-12-33(23)28(36)34-14-10-21-20(16-29)7-3-8-24(21)34;29-17-19-4-1-7-24(14-19)32-28(35)33-13-3-8-26(33)21-5-2-6-22(15-21)27(34)31-25-10-9-20-11-12-30-18-23(20)16-25;29-17-19-6-9-24(10-7-19)32-28(35)33-14-2-5-26(33)21-3-1-4-22(15-21)27(34)31-25-11-8-20-12-13-30-18-23(20)16-25;1-31-12-10-20-22(15-31)36-25(29-20)30-24(34)18-7-2-5-16(13-18)21-9-4-11-32(21)26(35)28-19-8-3-6-17(14-19)23(27)33;1-31-13-11-20-22(15-31)36-25(29-20)30-24(34)18-5-2-4-17(14-18)21-6-3-12-32(21)26(35)28-19-9-7-16(8-10-19)23(27)33;1-29-11-10-22-23(16-29)33-25(27-22)28-24(31)18-3-2-4-20(13-18)32-21-9-12-30(15-21)19-7-5-17(14-26)6-8-19/h4,6-7,11-14,16,22,24H,5,8-10,15,17H2,1-3H3,(H,33,34,37);3,5-6,8-11,15-17,25,30H,4,7,12-14,18H2,1-2H3,(H,31,33);2-3,5-8,15,23H,4,9-14,17H2,1H3,(H,30,31,35);1-2,4-7,9-10,14-16,26,30H,3,8,11-13,18H2,(H,31,34)(H,32,35);1,3-4,6-11,15-16,26,30H,2,5,12-14,18H2,(H,31,34)(H,32,35);2-3,5-8,13-14,21H,4,9-12,15H2,1H3,(H2,27,33)(H,28,35)(H,29,30,34);2,4-5,7-10,14,21H,3,6,11-13,15H2,1H3,(H2,27,33)(H,28,35)(H,29,30,34);2-8,13,21H,9-12,15-16H2,1H3,(H,27,28,31)/t22-,24+;;23-;;;3*21-/m0.1..111/s1
InChIKeyKAUIKXISSBAUQM-JZFYWFLESA-N
MW3970.90 g/mol
LogP36.04
Rot. Bonds38

About (2R)-N-(3-carbamoylphenyl)-2-[3-[(5-methyl-6,7-dihydro-4H-[1,3]thiazolo[5,4-c]pyridin-2-yl)carbamoyl]phenyl]pyrrolidine-1-carboxamide;(2R)-N-(4-carbamoylphenyl)-2-[3-[(5-methyl-6,7-dihydro-4H-[1,3]thiazolo[5,4-c]pyridin-2-yl)carbamoyl]phenyl]pyrrolidine-1-carboxamide;3-[(2R)-1-(4-cyano-2,3-dihydroindole-1-carbonyl)pyrrolidin-2-yl]-N-(5-methyl-6,7-dihydro-4H-[1,3]thiazolo[5,4-c]pyridin-2-yl)benzamide;3-[(3R)-1-(4-cyanophenyl)pyrrolidin-3-yl]oxy-N-(5-methyl-6,7-dihydro-4H-[1,3]thiazolo[5,4-c]pyridin-2-yl)benzamide;N-(3-cyanophenyl)-2-[3-(1,2,3,4-tetrahydroisoquinolin-7-ylcarbamoyl)phenyl]pyrrolidine-1-carboxamide;N-(4-cyanophenyl)-2-[3-(1,2,3,4-tetrahydroisoquinolin-7-ylcarbamoyl)phenyl]pyrrolidine-1-carboxamide;3-[1-(3,4-dimethoxybenzoyl)pyrrolidin-2-yl]-N-(1,2,3,4-tetrahydroisoquinolin-7-yl)benzamide;N-[(6S)-6-(dimethylamino)-4,5,6,7-tetrahydro-1,3-benzothiazol-2-yl]-3-[(2R)-1-(4-methyl-2-pyridin-4-yl-1,3-thiazole-5-carbonyl)pyrrolidin-2-yl]benzamide

(2R)-N-(3-carbamoylphenyl)-2-[3-[(5-methyl-6,7-dihydro-4H-[1,3]thiazolo[5,4-c]pyridin-2-yl)carbamoyl]phenyl]pyrrolidine-1-carboxamide;(2R)-N-(4-carbamoylphenyl)-2-[3-[(5-methyl-6,7-dihydro-4H-[1,3]thiazolo[5,4-c]pyridin-2-yl)carbamoyl]phenyl]pyrrolidine-1-carboxamide;3-[(2R)-1-(4-cyano-2,3-dihydroindole-1-carbonyl)pyrrolidin-2-yl]-N-(5-methyl-6,7-dihydro-4H-[1,3]thiazolo[5,4-c]pyridin-2-yl)benzamide;3-[(3R)-1-(4-cyanophenyl)pyrrolidin-3-yl]oxy-N-(5-methyl-6,7-dihydro-4H-[1,3]thiazolo[5,4-c]pyridin-2-yl)benzamide;N-(3-cyanophenyl)-2-[3-(1,2,3,4-tetrahydroisoquinolin-7-ylcarbamoyl)phenyl]pyrrolidine-1-carboxamide;N-(4-cyanophenyl)-2-[3-(1,2,3,4-tetrahydroisoquinolin-7-ylcarbamoyl)phenyl]pyrrolidine-1-carboxamide;3-[1-(3,4-dimethoxybenzoyl)pyrrolidin-2-yl]-N-(1,2,3,4-tetrahydroisoquinolin-7-yl)benzamide;N-[(6S)-6-(dimethylamino)-4,5,6,7-tetrahydro-1,3-benzothiazol-2-yl]-3-[(2R)-1-(4-methyl-2-pyridin-4-yl-1,3-thiazole-5-carbonyl)pyrrolidin-2-yl]benzamide (PubChem CID 159080512) has the molecular formula C220H226N42O20S6 and a molecular weight of 3970.90 g/mol. Its IUPAC name is (2R)-N-(3-carbamoylphenyl)-2-[3-[(5-methyl-6,7-dihydro-4H-[1,3]thiazolo[5,4-c]pyridin-2-yl)carbamoyl]phenyl]pyrrolidine-1-carboxamide;(2R)-N-(4-carbamoylphenyl)-2-[3-[(5-methyl-6,7-dihydro-4H-[1,3]thiazolo[5,4-c]pyridin-2-yl)carbamoyl]phenyl]pyrrolidine-1-carboxamide;3-[(2R)-1-(4-cyano-2,3-dihydroindole-1-carbonyl)pyrrolidin-2-yl]-N-(5-methyl-6,7-dihydro-4H-[1,3]thiazolo[5,4-c]pyridin-2-yl)benzamide;3-[(3R)-1-(4-cyanophenyl)pyrrolidin-3-yl]oxy-N-(5-methyl-6,7-dihydro-4H-[1,3]thiazolo[5,4-c]pyridin-2-yl)benzamide;N-(3-cyanophenyl)-2-[3-(1,2,3,4-tetrahydroisoquinolin-7-ylcarbamoyl)phenyl]pyrrolidine-1-carboxamide;N-(4-cyanophenyl)-2-[3-(1,2,3,4-tetrahydroisoquinolin-7-ylcarbamoyl)phenyl]pyrrolidine-1-carboxamide;3-[1-(3,4-dimethoxybenzoyl)pyrrolidin-2-yl]-N-(1,2,3,4-tetrahydroisoquinolin-7-yl)benzamide;N-[(6S)-6-(dimethylamino)-4,5,6,7-tetrahydro-1,3-benzothiazol-2-yl]-3-[(2R)-1-(4-methyl-2-pyridin-4-yl-1,3-thiazole-5-carbonyl)pyrrolidin-2-yl]benzamide.

Molecular Properties

Compound Name(2R)-N-(3-carbamoylphenyl)-2-[3-[(5-methyl-6,7-dihydro-4H-[1,3]thiazolo[5,4-c]pyridin-2-yl)carbamoyl]phenyl]pyrrolidine-1-carboxamide;(2R)-N-(4-carbamoylphenyl)-2-[3-[(5-methyl-6,7-dihydro-4H-[1,3]thiazolo[5,4-c]pyridin-2-yl)carbamoyl]phenyl]pyrrolidine-1-carboxamide;3-[(2R)-1-(4-cyano-2,3-dihydroindole-1-carbonyl)pyrrolidin-2-yl]-N-(5-methyl-6,7-dihydro-4H-[1,3]thiazolo[5,4-c]pyridin-2-yl)benzamide;3-[(3R)-1-(4-cyanophenyl)pyrrolidin-3-yl]oxy-N-(5-methyl-6,7-dihydro-4H-[1,3]thiazolo[5,4-c]pyridin-2-yl)benzamide;N-(3-cyanophenyl)-2-[3-(1,2,3,4-tetrahydroisoquinolin-7-ylcarbamoyl)phenyl]pyrrolidine-1-carboxamide;N-(4-cyanophenyl)-2-[3-(1,2,3,4-tetrahydroisoquinolin-7-ylcarbamoyl)phenyl]pyrrolidine-1-carboxamide;3-[1-(3,4-dimethoxybenzoyl)pyrrolidin-2-yl]-N-(1,2,3,4-tetrahydroisoquinolin-7-yl)benzamide;N-[(6S)-6-(dimethylamino)-4,5,6,7-tetrahydro-1,3-benzothiazol-2-yl]-3-[(2R)-1-(4-methyl-2-pyridin-4-yl-1,3-thiazole-5-carbonyl)pyrrolidin-2-yl]benzamide
PubChem CID159080512
Molecular FormulaC220H226N42O20S6
Molecular Weight3970.90 g/mol
Exact Mass3967.63
IUPAC Name(2R)-N-(3-carbamoylphenyl)-2-[3-[(5-methyl-6,7-dihydro-4H-[1,3]thiazolo[5,4-c]pyridin-2-yl)carbamoyl]phenyl]pyrrolidine-1-carboxamide;(2R)-N-(4-carbamoylphenyl)-2-[3-[(5-methyl-6,7-dihydro-4H-[1,3]thiazolo[5,4-c]pyridin-2-yl)carbamoyl]phenyl]pyrrolidine-1-carboxamide;3-[(2R)-1-(4-cyano-2,3-dihydroindole-1-carbonyl)pyrrolidin-2-yl]-N-(5-methyl-6,7-dihydro-4H-[1,3]thiazolo[5,4-c]pyridin-2-yl)benzamide;3-[(3R)-1-(4-cyanophenyl)pyrrolidin-3-yl]oxy-N-(5-methyl-6,7-dihydro-4H-[1,3]thiazolo[5,4-c]pyridin-2-yl)benzamide;N-(3-cyanophenyl)-2-[3-(1,2,3,4-tetrahydroisoquinolin-7-ylcarbamoyl)phenyl]pyrrolidine-1-carboxamide;N-(4-cyanophenyl)-2-[3-(1,2,3,4-tetrahydroisoquinolin-7-ylcarbamoyl)phenyl]pyrrolidine-1-carboxamide;3-[1-(3,4-dimethoxybenzoyl)pyrrolidin-2-yl]-N-(1,2,3,4-tetrahydroisoquinolin-7-yl)benzamide;N-[(6S)-6-(dimethylamino)-4,5,6,7-tetrahydro-1,3-benzothiazol-2-yl]-3-[(2R)-1-(4-methyl-2-pyridin-4-yl-1,3-thiazole-5-carbonyl)pyrrolidin-2-yl]benzamide
SMILESCN1CCc2nc(NC(=O)c3cccc(O[C@@H]4CCN(c5ccc(C#N)cc5)C4)c3)sc2C1.CN1CCc2nc(NC(=O)c3cccc([C@H]4CCCN4C(=O)N4CCc5c(C#N)cccc54)c3)sc2C1.CN1CCc2nc(NC(=O)c3cccc([C@H]4CCCN4C(=O)Nc4ccc(C(N)=O)cc4)c3)sc2C1.CN1CCc2nc(NC(=O)c3cccc([C@H]4CCCN4C(=O)Nc4cccc(C(N)=O)c4)c3)sc2C1.COc1ccc(C(=O)N2CCCC2c2cccc(C(=O)Nc3ccc4c(c3)CNCC4)c2)cc1OC.Cc1nc(-c2ccncc2)sc1C(=O)N1CCC[C@@H]1c1cccc(C(=O)Nc2nc3c(s2)C[C@@H](N(C)C)CC3)c1.N#Cc1ccc(NC(=O)N2CCCC2c2cccc(C(=O)Nc3ccc4c(c3)CNCC4)c2)cc1.N#Cc1cccc(NC(=O)N2CCCC2c2cccc(C(=O)Nc3ccc4c(c3)CNCC4)c2)c1
InChIInChI=1S/C30H32N6O2S2.C29H31N3O4.C28H28N6O2S.2C28H27N5O2.2C26H28N6O3S.C25H25N5O2S/c1-18-26(40-28(32-18)19-11-13-31-14-12-19)29(38)36-15-5-8-24(36)20-6-4-7-21(16-20)27(37)34-30-33-23-10-9-22(35(2)3)17-25(23)39-30;1-35-26-11-9-22(17-27(26)36-2)29(34)32-14-4-7-25(32)20-5-3-6-21(15-20)28(33)31-24-10-8-19-12-13-30-18-23(19)16-24;1-32-13-11-22-25(17-32)37-27(30-22)31-26(35)19-6-2-5-18(15-19)23-9-4-12-33(23)28(36)34-14-10-21-20(16-29)7-3-8-24(21)34;29-17-19-4-1-7-24(14-19)32-28(35)33-13-3-8-26(33)21-5-2-6-22(15-21)27(34)31-25-10-9-20-11-12-30-18-23(20)16-25;29-17-19-6-9-24(10-7-19)32-28(35)33-14-2-5-26(33)21-3-1-4-22(15-21)27(34)31-25-11-8-20-12-13-30-18-23(20)16-25;1-31-12-10-20-22(15-31)36-25(29-20)30-24(34)18-7-2-5-16(13-18)21-9-4-11-32(21)26(35)28-19-8-3-6-17(14-19)23(27)33;1-31-13-11-20-22(15-31)36-25(29-20)30-24(34)18-5-2-4-17(14-18)21-6-3-12-32(21)26(35)28-19-9-7-16(8-10-19)23(27)33;1-29-11-10-22-23(16-29)33-25(27-22)28-24(31)18-3-2-4-20(13-18)32-21-9-12-30(15-21)19-7-5-17(14-26)6-8-19/h4,6-7,11-14,16,22,24H,5,8-10,15,17H2,1-3H3,(H,33,34,37);3,5-6,8-11,15-17,25,30H,4,7,12-14,18H2,1-2H3,(H,31,33);2-3,5-8,15,23H,4,9-14,17H2,1H3,(H,30,31,35);1-2,4-7,9-10,14-16,26,30H,3,8,11-13,18H2,(H,31,34)(H,32,35);1,3-4,6-11,15-16,26,30H,2,5,12-14,18H2,(H,31,34)(H,32,35);2-3,5-8,13-14,21H,4,9-12,15H2,1H3,(H2,27,33)(H,28,35)(H,29,30,34);2,4-5,7-10,14,21H,3,6,11-13,15H2,1H3,(H2,27,33)(H,28,35)(H,29,30,34);2-8,13,21H,9-12,15-16H2,1H3,(H,27,28,31)/t22-,24+;;23-;;;3*21-/m0.1..111/s1
InChIKeyKAUIKXISSBAUQM-JZFYWFLESA-N
XLogP36.04
TPSA781.12 Ų
H-Bond Donors17
H-Bond Acceptors46
Rotatable Bonds38
Heavy Atoms288
Complexity—

Lipinski Rule of Five

4 violations

RuleValue
MW ≤ 5003970.90
LogP ≤ 536.04
H-Bond Donors ≤ 517
H-Bond Acceptors ≤ 1046

Analyze (2R)-N-(3-carbamoylphenyl)-2-[3-[(5-methyl-6,7-dihydro-4H-[1,3]thiazolo[5,4-c]pyridin-2-yl)carbamoyl]phenyl]pyrrolidine-1-carboxamide;(2R)-N-(4-carbamoylphenyl)-2-[3-[(5-methyl-6,7-dihydro-4H-[1,3]thiazolo[5,4-c]pyridin-2-yl)carbamoyl]phenyl]pyrrolidine-1-carboxamide;3-[(2R)-1-(4-cyano-2,3-dihydroindole-1-carbonyl)pyrrolidin-2-yl]-N-(5-methyl-6,7-dihydro-4H-[1,3]thiazolo[5,4-c]pyridin-2-yl)benzamide;3-[(3R)-1-(4-cyanophenyl)pyrrolidin-3-yl]oxy-N-(5-methyl-6,7-dihydro-4H-[1,3]thiazolo[5,4-c]pyridin-2-yl)benzamide;N-(3-cyanophenyl)-2-[3-(1,2,3,4-tetrahydroisoquinolin-7-ylcarbamoyl)phenyl]pyrrolidine-1-carboxamide;N-(4-cyanophenyl)-2-[3-(1,2,3,4-tetrahydroisoquinolin-7-ylcarbamoyl)phenyl]pyrrolidine-1-carboxamide;3-[1-(3,4-dimethoxybenzoyl)pyrrolidin-2-yl]-N-(1,2,3,4-tetrahydroisoquinolin-7-yl)benzamide;N-[(6S)-6-(dimethylamino)-4,5,6,7-tetrahydro-1,3-benzothiazol-2-yl]-3-[(2R)-1-(4-methyl-2-pyridin-4-yl-1,3-thiazole-5-carbonyl)pyrrolidin-2-yl]benzamide with MolForge

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Related Compounds

4-(aminomethyl)-N-[4-methyl-3-[(4-pyridin-3-yl-1,3-thiazol-2-yl)amino]phenyl]benzamide;3-cyano-N-[4-methyl-3-[(4-pyridin-3-yl-1,3-thiazol-2-yl)amino]phenyl]benzamide;2-fluoro-N-[4-methyl-3-[(4-pyridin-3-yl-1,3-thiazol-2-yl)amino]phenyl]-3-(trifluoromethyl)benzamide;N-[4-methyl-3-[(4-pyridin-3-yl-1,3-thiazol-2-yl)amino]phenyl]-3-(2-morpholin-4-ylethoxy)benzamide;4-methyl-3-[(4-pyridin-3-yl-1,3-thiazol-2-yl)methyl]benzamide;N-[4-methyl-3-[(4-pyridin-3-yl-1,3-thiazol-2-yl)methyl]phenyl]-4-pyridin-4-ylbenzamide
CID 173158317
CID 157199801
CID 157199801
CID 157208152
CID 157208152
CID 157299358
CID 157299358
N-[6-(2-amino-1,3-thiazol-5-yl)isoquinolin-3-yl]-4-cyclohexyloxybenzamide;N-[6-(2-amino-1,3-thiazol-5-yl)isoquinolin-3-yl]-4-[(dimethylamino)methyl]benzamide;N-[6-(2-amino-1,3-thiazol-5-yl)isoquinolin-3-yl]-4-(1-fluoroethoxy)benzamide;N-[6-(2-amino-1,3-thiazol-5-yl)isoquinolin-3-yl]-4-methylbenzamide;N-[6-(2-amino-1,3-thiazol-5-yl)isoquinolin-3-yl]-3-(4-methylpiperazin-1-yl)benzamide;N-[6-(2-amino-1,3-thiazol-5-yl)isoquinolin-3-yl]-3-(1-methylpiperidin-4-yl)oxybenzamide;5-N-[6-(2-amino-1,3-thiazol-5-yl)isoquinolin-3-yl]-2-N-methylpyridine-2,5-dicarboxamide;N-[6-(2-amino-1,3-thiazol-5-yl)isoquinolin-3-yl]-4-propan-2-yloxybenzamide;N-[6-(2-amino-1,3-thiazol-5-yl)isoquinolin-3-yl]-3-(pyrrolidin-1-ylmethyl)benzamide
CID 157878231
3-[1-(3-cyanobenzoyl)piperidin-3-yl]-N-(5-methyl-6,7-dihydro-4H-[1,3]thiazolo[5,4-c]pyridin-2-yl)benzamide;3-[1-(4-cyanobenzoyl)piperidin-3-yl]-N-(5-methyl-6,7-dihydro-4H-[1,3]thiazolo[5,4-c]pyridin-2-yl)benzamide;3,4-dimethoxy-N-[(1R)-1-[3-[(2-methyl-3,4-dihydro-1H-isoquinolin-7-yl)carbamoyl]phenyl]ethyl]benzamide;N-[(6S)-6-morpholin-4-yl-4,5,6,7-tetrahydro-1,3-benzothiazol-2-yl]-3-[(2R)-1-(3-pyridin-4-yl-1H-pyrazole-5-carbonyl)pyrrolidin-2-yl]benzamide;N-[(6S)-6-morpholin-4-yl-4,5,6,7-tetrahydro-1,3-benzothiazol-2-yl]-3-[(2R)-1-[3-(2H-pyrrol-4-yl)benzoyl]pyrrolidin-2-yl]benzamide
CID 157903080
2-(5,6-dimethoxy-3-oxo-1H-isoindol-2-yl)-N-(6-methyl-4-piperazin-1-yl-3-pyridinyl)-1,3-thiazole-4-carboxamide;methane;2-[5-(2-methoxyethoxy)-3-oxo-1H-isoindol-2-yl]-N-(6-methyl-4-piperazin-1-yl-3-pyridinyl)-1,3-thiazole-4-carboxamide;2-(5-methoxy-3-oxo-1H-isoindol-2-yl)-N-(6-methyl-4-piperazin-1-yl-3-pyridinyl)-1,3-thiazole-4-carboxamide;2-(6-methoxy-3-oxo-1H-isoindol-2-yl)-N-(6-methyl-4-piperazin-1-yl-3-pyridinyl)-1,3-thiazole-4-carboxamide
CID 158249093
2-[5-[2-(dimethylamino)ethoxy]-3-oxo-1H-isoindol-2-yl]-N-(4-piperazin-1-yl-3-pyridinyl)-1,3-thiazole-4-carboxamide;2-(6-methoxy-1-oxo-3,4-dihydroisoquinolin-2-yl)-N-(4-piperazin-1-yl-3-pyridinyl)-1,3-thiazole-4-carboxamide;2-[5-(2-morpholin-4-ylethoxy)-3-oxo-1H-isoindol-2-yl]-N-(4-piperazin-1-yl-3-pyridinyl)-1,3-thiazole-4-carboxamide;2-[6-(2-morpholin-4-ylethoxy)-3-oxo-1H-isoindol-2-yl]-N-(4-piperazin-1-yl-3-pyridinyl)-1,3-thiazole-4-carboxamide;2-(1-oxo-3,4-dihydroisoquinolin-2-yl)-N-(4-piperazin-1-yl-3-pyridinyl)-1,3-thiazole-4-carboxamide
CID 158500904
2-[4-[2-[2-[2-[2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindol-5-yl]oxyethoxy]ethoxy]ethyl]piperazin-1-yl]-N-[1-(1H-indol-3-yl)hexan-2-yl]-1,3-thiazole-5-carboxamide;2-(2,6-dioxopiperidin-3-yl)-5-[2-(2-propoxyethoxy)ethoxy]isoindole-1,3-dione;3-(1H-indol-3-ylmethyl)-1-(2-piperazin-1-yl-1,3-thiazol-5-yl)heptan-1-one
CID 158576682
2-[5-[2-(dimethylamino)ethoxy]-3-oxo-1H-isoindol-2-yl]-N-(4-piperazin-1-yl-3-pyridinyl)-1,3-thiazole-4-carboxamide;bis(2-(6-methoxy-1-oxo-3,4-dihydroisoquinolin-2-yl)-N-(4-piperazin-1-yl-3-pyridinyl)-1,3-thiazole-4-carboxamide);2-[5-(2-morpholin-4-ylethoxy)-3-oxo-1H-isoindol-2-yl]-N-(4-piperazin-1-yl-3-pyridinyl)-1,3-thiazole-4-carboxamide;2-[6-(2-morpholin-4-ylethoxy)-3-oxo-1H-isoindol-2-yl]-N-(4-piperazin-1-yl-3-pyridinyl)-1,3-thiazole-4-carboxamide
CID 158689275
1-(1,3-benzodioxol-5-yl)-3-[4-[1-(2-ethylbenzoyl)-2,3-dihydroindol-5-yl]-5-methyl-1,3-thiazol-2-yl]propan-2-one;tris(1-(1,3-benzodioxol-5-yl)-3-[5-methyl-4-[1-(2-methylbenzoyl)-2,3-dihydroindol-5-yl]-1,3-thiazol-2-yl]propan-2-one);2-(4-methoxyphenyl)-N-[5-methyl-4-[2-methyl-1-(2-methylbenzoyl)-2,3-dihydroindol-5-yl]-1,3-thiazol-2-yl]acetamide;2-(6-methoxy-3-pyridinyl)-N-[5-methyl-4-[1-(2-methylbenzoyl)-2,3-dihydroindol-5-yl]-1,3-thiazol-2-yl]acetamide;N-[5-methyl-4-[1-(2-methylbenzoyl)-2,3-dihydroindol-5-yl]-1,3-thiazol-2-yl]-2-(oxan-4-yl)acetamide
CID 158928475
1-benzyl-6-oxo-N-(4-pyridin-2-yl-1,3-thiazol-2-yl)pyridazine-3-carboxamide;2-(3,4-dimethoxyphenyl)-N-(4-pyridin-2-yl-1,3-thiazol-2-yl)acetamide;2-(4-methoxyphenyl)-N-(4-pyridin-2-yl-1,3-thiazol-2-yl)acetamide;3-methyl-N-(4-pyridin-2-yl-1,3-thiazol-2-yl)-1-benzofuran-2-carboxamide;3-oxo-N-(4-pyridin-2-yl-1,3-thiazol-2-yl)-4H-1,4-benzoxazine-7-carboxamide;6-oxo-N-(4-pyridin-2-yl-1,3-thiazol-2-yl)-1H-pyridine-3-carboxamide;2-(4-oxoquinazolin-3-yl)-N-(4-pyridin-2-yl-1,3-thiazol-2-yl)acetamide;N-(4-pyridin-3-yl-1,3-thiazol-2-yl)pyridine-2-carboxamide
CID 159227714

Frequently Asked Questions

What is the IUPAC name of (2R)-N-(3-carbamoylphenyl)-2-[3-[(5-methyl-6,7-dihydro-4H-[1,3]thiazolo[5,4-c]pyridin-2-yl)carbamoyl]phenyl]pyrrolidine-1-carboxamide;(2R)-N-(4-carbamoylphenyl)-2-[3-[(5-methyl-6,7-dihydro-4H-[1,3]thiazolo[5,4-c]pyridin-2-yl)carbamoyl]phenyl]pyrrolidine-1-carboxamide;3-[(2R)-1-(4-cyano-2,3-dihydroindole-1-carbonyl)pyrrolidin-2-yl]-N-(5-methyl-6,7-dihydro-4H-[1,3]thiazolo[5,4-c]pyridin-2-yl)benzamide;3-[(3R)-1-(4-cyanophenyl)pyrrolidin-3-yl]oxy-N-(5-methyl-6,7-dihydro-4H-[1,3]thiazolo[5,4-c]pyridin-2-yl)benzamide;N-(3-cyanophenyl)-2-[3-(1,2,3,4-tetrahydroisoquinolin-7-ylcarbamoyl)phenyl]pyrrolidine-1-carboxamide;N-(4-cyanophenyl)-2-[3-(1,2,3,4-tetrahydroisoquinolin-7-ylcarbamoyl)phenyl]pyrrolidine-1-carboxamide;3-[1-(3,4-dimethoxybenzoyl)pyrrolidin-2-yl]-N-(1,2,3,4-tetrahydroisoquinolin-7-yl)benzamide;N-[(6S)-6-(dimethylamino)-4,5,6,7-tetrahydro-1,3-benzothiazol-2-yl]-3-[(2R)-1-(4-methyl-2-pyridin-4-yl-1,3-thiazole-5-carbonyl)pyrrolidin-2-yl]benzamide?
The IUPAC name of (2R)-N-(3-carbamoylphenyl)-2-[3-[(5-methyl-6,7-dihydro-4H-[1,3]thiazolo[5,4-c]pyridin-2-yl)carbamoyl]phenyl]pyrrolidine-1-carboxamide;(2R)-N-(4-carbamoylphenyl)-2-[3-[(5-methyl-6,7-dihydro-4H-[1,3]thiazolo[5,4-c]pyridin-2-yl)carbamoyl]phenyl]pyrrolidine-1-carboxamide;3-[(2R)-1-(4-cyano-2,3-dihydroindole-1-carbonyl)pyrrolidin-2-yl]-N-(5-methyl-6,7-dihydro-4H-[1,3]thiazolo[5,4-c]pyridin-2-yl)benzamide;3-[(3R)-1-(4-cyanophenyl)pyrrolidin-3-yl]oxy-N-(5-methyl-6,7-dihydro-4H-[1,3]thiazolo[5,4-c]pyridin-2-yl)benzamide;N-(3-cyanophenyl)-2-[3-(1,2,3,4-tetrahydroisoquinolin-7-ylcarbamoyl)phenyl]pyrrolidine-1-carboxamide;N-(4-cyanophenyl)-2-[3-(1,2,3,4-tetrahydroisoquinolin-7-ylcarbamoyl)phenyl]pyrrolidine-1-carboxamide;3-[1-(3,4-dimethoxybenzoyl)pyrrolidin-2-yl]-N-(1,2,3,4-tetrahydroisoquinolin-7-yl)benzamide;N-[(6S)-6-(dimethylamino)-4,5,6,7-tetrahydro-1,3-benzothiazol-2-yl]-3-[(2R)-1-(4-methyl-2-pyridin-4-yl-1,3-thiazole-5-carbonyl)pyrrolidin-2-yl]benzamide (CID 159080512) is (2R)-N-(3-carbamoylphenyl)-2-[3-[(5-methyl-6,7-dihydro-4H-[1,3]thiazolo[5,4-c]pyridin-2-yl)carbamoyl]phenyl]pyrrolidine-1-carboxamide;(2R)-N-(4-carbamoylphenyl)-2-[3-[(5-methyl-6,7-dihydro-4H-[1,3]thiazolo[5,4-c]pyridin-2-yl)carbamoyl]phenyl]pyrrolidine-1-carboxamide;3-[(2R)-1-(4-cyano-2,3-dihydroindole-1-carbonyl)pyrrolidin-2-yl]-N-(5-methyl-6,7-dihydro-4H-[1,3]thiazolo[5,4-c]pyridin-2-yl)benzamide;3-[(3R)-1-(4-cyanophenyl)pyrrolidin-3-yl]oxy-N-(5-methyl-6,7-dihydro-4H-[1,3]thiazolo[5,4-c]pyridin-2-yl)benzamide;N-(3-cyanophenyl)-2-[3-(1,2,3,4-tetrahydroisoquinolin-7-ylcarbamoyl)phenyl]pyrrolidine-1-carboxamide;N-(4-cyanophenyl)-2-[3-(1,2,3,4-tetrahydroisoquinolin-7-ylcarbamoyl)phenyl]pyrrolidine-1-carboxamide;3-[1-(3,4-dimethoxybenzoyl)pyrrolidin-2-yl]-N-(1,2,3,4-tetrahydroisoquinolin-7-yl)benzamide;N-[(6S)-6-(dimethylamino)-4,5,6,7-tetrahydro-1,3-benzothiazol-2-yl]-3-[(2R)-1-(4-methyl-2-pyridin-4-yl-1,3-thiazole-5-carbonyl)pyrrolidin-2-yl]benzamide.
What is the SMILES notation for (2R)-N-(3-carbamoylphenyl)-2-[3-[(5-methyl-6,7-dihydro-4H-[1,3]thiazolo[5,4-c]pyridin-2-yl)carbamoyl]phenyl]pyrrolidine-1-carboxamide;(2R)-N-(4-carbamoylphenyl)-2-[3-[(5-methyl-6,7-dihydro-4H-[1,3]thiazolo[5,4-c]pyridin-2-yl)carbamoyl]phenyl]pyrrolidine-1-carboxamide;3-[(2R)-1-(4-cyano-2,3-dihydroindole-1-carbonyl)pyrrolidin-2-yl]-N-(5-methyl-6,7-dihydro-4H-[1,3]thiazolo[5,4-c]pyridin-2-yl)benzamide;3-[(3R)-1-(4-cyanophenyl)pyrrolidin-3-yl]oxy-N-(5-methyl-6,7-dihydro-4H-[1,3]thiazolo[5,4-c]pyridin-2-yl)benzamide;N-(3-cyanophenyl)-2-[3-(1,2,3,4-tetrahydroisoquinolin-7-ylcarbamoyl)phenyl]pyrrolidine-1-carboxamide;N-(4-cyanophenyl)-2-[3-(1,2,3,4-tetrahydroisoquinolin-7-ylcarbamoyl)phenyl]pyrrolidine-1-carboxamide;3-[1-(3,4-dimethoxybenzoyl)pyrrolidin-2-yl]-N-(1,2,3,4-tetrahydroisoquinolin-7-yl)benzamide;N-[(6S)-6-(dimethylamino)-4,5,6,7-tetrahydro-1,3-benzothiazol-2-yl]-3-[(2R)-1-(4-methyl-2-pyridin-4-yl-1,3-thiazole-5-carbonyl)pyrrolidin-2-yl]benzamide?
The canonical SMILES for (2R)-N-(3-carbamoylphenyl)-2-[3-[(5-methyl-6,7-dihydro-4H-[1,3]thiazolo[5,4-c]pyridin-2-yl)carbamoyl]phenyl]pyrrolidine-1-carboxamide;(2R)-N-(4-carbamoylphenyl)-2-[3-[(5-methyl-6,7-dihydro-4H-[1,3]thiazolo[5,4-c]pyridin-2-yl)carbamoyl]phenyl]pyrrolidine-1-carboxamide;3-[(2R)-1-(4-cyano-2,3-dihydroindole-1-carbonyl)pyrrolidin-2-yl]-N-(5-methyl-6,7-dihydro-4H-[1,3]thiazolo[5,4-c]pyridin-2-yl)benzamide;3-[(3R)-1-(4-cyanophenyl)pyrrolidin-3-yl]oxy-N-(5-methyl-6,7-dihydro-4H-[1,3]thiazolo[5,4-c]pyridin-2-yl)benzamide;N-(3-cyanophenyl)-2-[3-(1,2,3,4-tetrahydroisoquinolin-7-ylcarbamoyl)phenyl]pyrrolidine-1-carboxamide;N-(4-cyanophenyl)-2-[3-(1,2,3,4-tetrahydroisoquinolin-7-ylcarbamoyl)phenyl]pyrrolidine-1-carboxamide;3-[1-(3,4-dimethoxybenzoyl)pyrrolidin-2-yl]-N-(1,2,3,4-tetrahydroisoquinolin-7-yl)benzamide;N-[(6S)-6-(dimethylamino)-4,5,6,7-tetrahydro-1,3-benzothiazol-2-yl]-3-[(2R)-1-(4-methyl-2-pyridin-4-yl-1,3-thiazole-5-carbonyl)pyrrolidin-2-yl]benzamide is CN1CCc2nc(NC(=O)c3cccc(O[C@@H]4CCN(c5ccc(C#N)cc5)C4)c3)sc2C1.CN1CCc2nc(NC(=O)c3cccc([C@H]4CCCN4C(=O)N4CCc5c(C#N)cccc54)c3)sc2C1.CN1CCc2nc(NC(=O)c3cccc([C@H]4CCCN4C(=O)Nc4ccc(C(N)=O)cc4)c3)sc2C1.CN1CCc2nc(NC(=O)c3cccc([C@H]4CCCN4C(=O)Nc4cccc(C(N)=O)c4)c3)sc2C1.COc1ccc(C(=O)N2CCCC2c2cccc(C(=O)Nc3ccc4c(c3)CNCC4)c2)cc1OC.Cc1nc(-c2ccncc2)sc1C(=O)N1CCC[C@@H]1c1cccc(C(=O)Nc2nc3c(s2)C[C@@H](N(C)C)CC3)c1.N#Cc1ccc(NC(=O)N2CCCC2c2cccc(C(=O)Nc3ccc4c(c3)CNCC4)c2)cc1.N#Cc1cccc(NC(=O)N2CCCC2c2cccc(C(=O)Nc3ccc4c(c3)CNCC4)c2)c1.
What is the InChIKey of (2R)-N-(3-carbamoylphenyl)-2-[3-[(5-methyl-6,7-dihydro-4H-[1,3]thiazolo[5,4-c]pyridin-2-yl)carbamoyl]phenyl]pyrrolidine-1-carboxamide;(2R)-N-(4-carbamoylphenyl)-2-[3-[(5-methyl-6,7-dihydro-4H-[1,3]thiazolo[5,4-c]pyridin-2-yl)carbamoyl]phenyl]pyrrolidine-1-carboxamide;3-[(2R)-1-(4-cyano-2,3-dihydroindole-1-carbonyl)pyrrolidin-2-yl]-N-(5-methyl-6,7-dihydro-4H-[1,3]thiazolo[5,4-c]pyridin-2-yl)benzamide;3-[(3R)-1-(4-cyanophenyl)pyrrolidin-3-yl]oxy-N-(5-methyl-6,7-dihydro-4H-[1,3]thiazolo[5,4-c]pyridin-2-yl)benzamide;N-(3-cyanophenyl)-2-[3-(1,2,3,4-tetrahydroisoquinolin-7-ylcarbamoyl)phenyl]pyrrolidine-1-carboxamide;N-(4-cyanophenyl)-2-[3-(1,2,3,4-tetrahydroisoquinolin-7-ylcarbamoyl)phenyl]pyrrolidine-1-carboxamide;3-[1-(3,4-dimethoxybenzoyl)pyrrolidin-2-yl]-N-(1,2,3,4-tetrahydroisoquinolin-7-yl)benzamide;N-[(6S)-6-(dimethylamino)-4,5,6,7-tetrahydro-1,3-benzothiazol-2-yl]-3-[(2R)-1-(4-methyl-2-pyridin-4-yl-1,3-thiazole-5-carbonyl)pyrrolidin-2-yl]benzamide?
The InChIKey is KAUIKXISSBAUQM-JZFYWFLESA-N. The full InChI is InChI=1S/C30H32N6O2S2.C29H31N3O4.C28H28N6O2S.2C28H27N5O2.2C26H28N6O3S.C25H25N5O2S/c1-18-26(40-28(32-18)19-11-13-31-14-12-19)29(38)36-15-5-8-24(36)20-6-4-7-21(16-20)27(37)34-30-33-23-10-9-22(35(2)3)17-25(23)39-30;1-35-26-11-9-22(17-27(26)36-2)29(34)32-14-4-7-25(32)20-5-3-6-21(15-20)28(33)31-24-10-8-19-12-13-30-18-23(19)16-24;1-32-13-11-22-25(17-32)37-27(30-22)31-26(35)19-6-2-5-18(15-19)23-9-4-12-33(23)28(36)34-14-10-21-20(16-29)7-3-8-24(21)34;29-17-19-4-1-7-24(14-19)32-28(35)33-13-3-8-26(33)21-5-2-6-22(15-21)27(34)31-25-10-9-20-11-12-30-18-23(20)16-25;29-17-19-6-9-24(10-7-19)32-28(35)33-14-2-5-26(33)21-3-1-4-22(15-21)27(34)31-25-11-8-20-12-13-30-18-23(20)16-25;1-31-12-10-20-22(15-31)36-25(29-20)30-24(34)18-7-2-5-16(13-18)21-9-4-11-32(21)26(35)28-19-8-3-6-17(14-19)23(27)33;1-31-13-11-20-22(15-31)36-25(29-20)30-24(34)18-5-2-4-17(14-18)21-6-3-12-32(21)26(35)28-19-9-7-16(8-10-19)23(27)33;1-29-11-10-22-23(16-29)33-25(27-22)28-24(31)18-3-2-4-20(13-18)32-21-9-12-30(15-21)19-7-5-17(14-26)6-8-19/h4,6-7,11-14,16,22,24H,5,8-10,15,17H2,1-3H3,(H,33,34,37);3,5-6,8-11,15-17,25,30H,4,7,12-14,18H2,1-2H3,(H,31,33);2-3,5-8,15,23H,4,9-14,17H2,1H3,(H,30,31,35);1-2,4-7,9-10,14-16,26,30H,3,8,11-13,18H2,(H,31,34)(H,32,35);1,3-4,6-11,15-16,26,30H,2,5,12-14,18H2,(H,31,34)(H,32,35);2-3,5-8,13-14,21H,4,9-12,15H2,1H3,(H2,27,33)(H,28,35)(H,29,30,34);2,4-5,7-10,14,21H,3,6,11-13,15H2,1H3,(H2,27,33)(H,28,35)(H,29,30,34);2-8,13,21H,9-12,15-16H2,1H3,(H,27,28,31)/t22-,24+;;23-;;;3*21-/m0.1..111/s1.
What are the key properties of (2R)-N-(3-carbamoylphenyl)-2-[3-[(5-methyl-6,7-dihydro-4H-[1,3]thiazolo[5,4-c]pyridin-2-yl)carbamoyl]phenyl]pyrrolidine-1-carboxamide;(2R)-N-(4-carbamoylphenyl)-2-[3-[(5-methyl-6,7-dihydro-4H-[1,3]thiazolo[5,4-c]pyridin-2-yl)carbamoyl]phenyl]pyrrolidine-1-carboxamide;3-[(2R)-1-(4-cyano-2,3-dihydroindole-1-carbonyl)pyrrolidin-2-yl]-N-(5-methyl-6,7-dihydro-4H-[1,3]thiazolo[5,4-c]pyridin-2-yl)benzamide;3-[(3R)-1-(4-cyanophenyl)pyrrolidin-3-yl]oxy-N-(5-methyl-6,7-dihydro-4H-[1,3]thiazolo[5,4-c]pyridin-2-yl)benzamide;N-(3-cyanophenyl)-2-[3-(1,2,3,4-tetrahydroisoquinolin-7-ylcarbamoyl)phenyl]pyrrolidine-1-carboxamide;N-(4-cyanophenyl)-2-[3-(1,2,3,4-tetrahydroisoquinolin-7-ylcarbamoyl)phenyl]pyrrolidine-1-carboxamide;3-[1-(3,4-dimethoxybenzoyl)pyrrolidin-2-yl]-N-(1,2,3,4-tetrahydroisoquinolin-7-yl)benzamide;N-[(6S)-6-(dimethylamino)-4,5,6,7-tetrahydro-1,3-benzothiazol-2-yl]-3-[(2R)-1-(4-methyl-2-pyridin-4-yl-1,3-thiazole-5-carbonyl)pyrrolidin-2-yl]benzamide?
(2R)-N-(3-carbamoylphenyl)-2-[3-[(5-methyl-6,7-dihydro-4H-[1,3]thiazolo[5,4-c]pyridin-2-yl)carbamoyl]phenyl]pyrrolidine-1-carboxamide;(2R)-N-(4-carbamoylphenyl)-2-[3-[(5-methyl-6,7-dihydro-4H-[1,3]thiazolo[5,4-c]pyridin-2-yl)carbamoyl]phenyl]pyrrolidine-1-carboxamide;3-[(2R)-1-(4-cyano-2,3-dihydroindole-1-carbonyl)pyrrolidin-2-yl]-N-(5-methyl-6,7-dihydro-4H-[1,3]thiazolo[5,4-c]pyridin-2-yl)benzamide;3-[(3R)-1-(4-cyanophenyl)pyrrolidin-3-yl]oxy-N-(5-methyl-6,7-dihydro-4H-[1,3]thiazolo[5,4-c]pyridin-2-yl)benzamide;N-(3-cyanophenyl)-2-[3-(1,2,3,4-tetrahydroisoquinolin-7-ylcarbamoyl)phenyl]pyrrolidine-1-carboxamide;N-(4-cyanophenyl)-2-[3-(1,2,3,4-tetrahydroisoquinolin-7-ylcarbamoyl)phenyl]pyrrolidine-1-carboxamide;3-[1-(3,4-dimethoxybenzoyl)pyrrolidin-2-yl]-N-(1,2,3,4-tetrahydroisoquinolin-7-yl)benzamide;N-[(6S)-6-(dimethylamino)-4,5,6,7-tetrahydro-1,3-benzothiazol-2-yl]-3-[(2R)-1-(4-methyl-2-pyridin-4-yl-1,3-thiazole-5-carbonyl)pyrrolidin-2-yl]benzamide has a molecular weight of 3970.90 g/mol, XLogP of 36.04, 38 rotatable bonds, 17 hydrogen bond donors, and 46 hydrogen bond acceptors.
Where does this data come from?
All data for (2R)-N-(3-carbamoylphenyl)-2-[3-[(5-methyl-6,7-dihydro-4H-[1,3]thiazolo[5,4-c]pyridin-2-yl)carbamoyl]phenyl]pyrrolidine-1-carboxamide;(2R)-N-(4-carbamoylphenyl)-2-[3-[(5-methyl-6,7-dihydro-4H-[1,3]thiazolo[5,4-c]pyridin-2-yl)carbamoyl]phenyl]pyrrolidine-1-carboxamide;3-[(2R)-1-(4-cyano-2,3-dihydroindole-1-carbonyl)pyrrolidin-2-yl]-N-(5-methyl-6,7-dihydro-4H-[1,3]thiazolo[5,4-c]pyridin-2-yl)benzamide;3-[(3R)-1-(4-cyanophenyl)pyrrolidin-3-yl]oxy-N-(5-methyl-6,7-dihydro-4H-[1,3]thiazolo[5,4-c]pyridin-2-yl)benzamide;N-(3-cyanophenyl)-2-[3-(1,2,3,4-tetrahydroisoquinolin-7-ylcarbamoyl)phenyl]pyrrolidine-1-carboxamide;N-(4-cyanophenyl)-2-[3-(1,2,3,4-tetrahydroisoquinolin-7-ylcarbamoyl)phenyl]pyrrolidine-1-carboxamide;3-[1-(3,4-dimethoxybenzoyl)pyrrolidin-2-yl]-N-(1,2,3,4-tetrahydroisoquinolin-7-yl)benzamide;N-[(6S)-6-(dimethylamino)-4,5,6,7-tetrahydro-1,3-benzothiazol-2-yl]-3-[(2R)-1-(4-methyl-2-pyridin-4-yl-1,3-thiazole-5-carbonyl)pyrrolidin-2-yl]benzamide is sourced from PubChem (CID 159080512), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).