8-(2,6-dimethylmorpholin-4-yl)-2-phenyl-1H-pyrazolo[4,3-c]quinolin-3-one;8-fluoro-2-(2-fluorophenyl)-7-(4-methylpiperazin-1-yl)-1H-pyrazolo[4,3-c]quinolin-3-one;8-fluoro-7-morpholin-4-yl-2-thiophen-3-yl-1H-pyrazolo[4,3-c]quinolin-3-one;2-(4-methoxyphenyl)-8-(4-propan-2-ylpiperazin-1-yl)-1H-pyrazolo[4,3-c]quinolin-3-one;2-phenyl-8-piperazin-1-yl-1H-pyrazolo[4,3-c]quinolin-3-one

C105H102F3N23O8S — CID 159105415

About 8-(2,6-dimethylmorpholin-4-yl)-2-phenyl-1H-pyrazolo[4,3-c]quinolin-3-one;8-fluoro-2-(2-fluorophenyl)-7-(4-methylpiperazin-1-yl)-1H-pyrazolo[4,3-c]quinolin-3-one;8-fluoro-7-morpholin-4-yl-2-thiophen-3-yl-1H-pyrazolo[4,3-c]quinolin-3-one;2-(4-methoxyphenyl)-8-(4-propan-2-ylpiperazin-1-yl)-1H-pyrazolo[4,3-c]quinolin-3-one;2-phenyl-8-piperazin-1-yl-1H-pyrazolo[4,3-c]quinolin-3-one

8-(2,6-dimethylmorpholin-4-yl)-2-phenyl-1H-pyrazolo[4,3-c]quinolin-3-one;8-fluoro-2-(2-fluorophenyl)-7-(4-methylpiperazin-1-yl)-1H-pyrazolo[4,3-c]quinolin-3-one;8-fluoro-7-morpholin-4-yl-2-thiophen-3-yl-1H-pyrazolo[4,3-c]quinolin-3-one;2-(4-methoxyphenyl)-8-(4-propan-2-ylpiperazin-1-yl)-1H-pyrazolo[4,3-c]quinolin-3-one;2-phenyl-8-piperazin-1-yl-1H-pyrazolo[4,3-c]quinolin-3-one (PubChem CID 159105415) has the molecular formula C105H102F3N23O8S and a molecular weight of 1903.18 g/mol. Its IUPAC name is 8-(2,6-dimethylmorpholin-4-yl)-2-phenyl-1H-pyrazolo[4,3-c]quinolin-3-one;8-fluoro-2-(2-fluorophenyl)-7-(4-methylpiperazin-1-yl)-1H-pyrazolo[4,3-c]quinolin-3-one;8-fluoro-7-morpholin-4-yl-2-thiophen-3-yl-1H-pyrazolo[4,3-c]quinolin-3-one;2-(4-methoxyphenyl)-8-(4-propan-2-ylpiperazin-1-yl)-1H-pyrazolo[4,3-c]quinolin-3-one;2-phenyl-8-piperazin-1-yl-1H-pyrazolo[4,3-c]quinolin-3-one.

Molecular Properties

• Compound Name: 8-(2,6-dimethylmorpholin-4-yl)-2-phenyl-1H-pyrazolo[4,3-c]quinolin-3-one;8-fluoro-2-(2-fluorophenyl)-7-(4-methylpiperazin-1-yl)-1H-pyrazolo[4,3-c]quinolin-3-one;8-fluoro-7-morpholin-4-yl-2-thiophen-3-yl-1H-pyrazolo[4,3-c]quinolin-3-one;2-(4-methoxyphenyl)-8-(4-propan-2-ylpiperazin-1-yl)-1H-pyrazolo[4,3-c]quinolin-3-one;2-phenyl-8-piperazin-1-yl-1H-pyrazolo[4,3-c]quinolin-3-one
• PubChem CID: 159105415
• Molecular Formula: C105H102F3N23O8S
• Molecular Weight: 1903.18 g/mol
• Exact Mass: 1901.80
• IUPAC Name: 8-(2,6-dimethylmorpholin-4-yl)-2-phenyl-1H-pyrazolo[4,3-c]quinolin-3-one;8-fluoro-2-(2-fluorophenyl)-7-(4-methylpiperazin-1-yl)-1H-pyrazolo[4,3-c]quinolin-3-one;8-fluoro-7-morpholin-4-yl-2-thiophen-3-yl-1H-pyrazolo[4,3-c]quinolin-3-one;2-(4-methoxyphenyl)-8-(4-propan-2-ylpiperazin-1-yl)-1H-pyrazolo[4,3-c]quinolin-3-one;2-phenyl-8-piperazin-1-yl-1H-pyrazolo[4,3-c]quinolin-3-one
• SMILES: CC1CN(c2ccc3ncc4c(=O)n(-c5ccccc5)[nH]c4c3c2)CC(C)O1.CN1CCN(c2cc3ncc4c(=O)n(-c5ccccc5F)[nH]c4c3cc2F)CC1.COc1ccc(-n2[nH]c3c(cnc4ccc(N5CCN(C(C)C)CC5)cc43)c2=O)cc1.O=c1c2cnc3cc(N4CCOCC4)c(F)cc3c2[nH]n1-c1ccsc1.O=c1c2cnc3ccc(N4CCNCC4)cc3c2[nH]n1-c1ccccc1
• InChI: InChI=1S/C24H27N5O2.C22H22N4O2.C21H19F2N5O.C20H19N5O.C18H15FN4O2S/c1-16(2)27-10-12-28(13-11-27)18-6-9-22-20(14-18)23-21(15-25-22)24(30)29(26-23)17-4-7-19(31-3)8-5-17;1-14-12-25(13-15(2)28-14)17-8-9-20-18(10-17)21-19(11-23-20)22(27)26(24-21)16-6-4-3-5-7-16;1-26-6-8-27(9-7-26)19-11-17-13(10-16(19)23)20-14(12-24-17)21(29)28(25-20)18-5-3-2-4-15(18)22;26-20-17-13-22-18-7-6-15(24-10-8-21-9-11-24)12-16(18)19(17)23-25(20)14-4-2-1-3-5-14;19-14-7-12-15(8-16(14)22-2-4-25-5-3-22)20-9-13-17(12)21-23(18(13)24)11-1-6-26-10-11/h4-9,14-16,26H,10-13H2,1-3H3;3-11,14-15,24H,12-13H2,1-2H3;2-5,10-12,25H,6-9H2,1H3;1-7,12-13,21,23H,8-11H2;1,6-10,21H,2-5H2
• InChIKey: ZDXSDTWPHRUDSJ-UHFFFAOYSA-N
• XLogP: 14.96
• TPSA: 315.80 Ų
• H-Bond Donors: 6
• H-Bond Acceptors: 27
• Rotatable Bonds: 12
• Heavy Atoms: 140
• Complexity: —

Lipinski Rule of Five

4 violations

Rule	Value
MW ≤ 500	1903.18
LogP ≤ 5	14.96
H-Bond Donors ≤ 5	6
H-Bond Acceptors ≤ 10	27

Computed Properties (RDKit)

• Structural Alerts: {'alert_name': 'het_65_B(7)', 'substructure': 'N/A'}

Frequently Asked Questions

What is the IUPAC name of 8-(2,6-dimethylmorpholin-4-yl)-2-phenyl-1H-pyrazolo[4,3-c]quinolin-3-one;8-fluoro-2-(2-fluorophenyl)-7-(4-methylpiperazin-1-yl)-1H-pyrazolo[4,3-c]quinolin-3-one;8-fluoro-7-morpholin-4-yl-2-thiophen-3-yl-1H-pyrazolo[4,3-c]quinolin-3-one;2-(4-methoxyphenyl)-8-(4-propan-2-ylpiperazin-1-yl)-1H-pyrazolo[4,3-c]quinolin-3-one;2-phenyl-8-piperazin-1-yl-1H-pyrazolo[4,3-c]quinolin-3-one?

The IUPAC name of 8-(2,6-dimethylmorpholin-4-yl)-2-phenyl-1H-pyrazolo[4,3-c]quinolin-3-one;8-fluoro-2-(2-fluorophenyl)-7-(4-methylpiperazin-1-yl)-1H-pyrazolo[4,3-c]quinolin-3-one;8-fluoro-7-morpholin-4-yl-2-thiophen-3-yl-1H-pyrazolo[4,3-c]quinolin-3-one;2-(4-methoxyphenyl)-8-(4-propan-2-ylpiperazin-1-yl)-1H-pyrazolo[4,3-c]quinolin-3-one;2-phenyl-8-piperazin-1-yl-1H-pyrazolo[4,3-c]quinolin-3-one (CID 159105415) is 8-(2,6-dimethylmorpholin-4-yl)-2-phenyl-1H-pyrazolo[4,3-c]quinolin-3-one;8-fluoro-2-(2-fluorophenyl)-7-(4-methylpiperazin-1-yl)-1H-pyrazolo[4,3-c]quinolin-3-one;8-fluoro-7-morpholin-4-yl-2-thiophen-3-yl-1H-pyrazolo[4,3-c]quinolin-3-one;2-(4-methoxyphenyl)-8-(4-propan-2-ylpiperazin-1-yl)-1H-pyrazolo[4,3-c]quinolin-3-one;2-phenyl-8-piperazin-1-yl-1H-pyrazolo[4,3-c]quinolin-3-one.

What is the SMILES notation for 8-(2,6-dimethylmorpholin-4-yl)-2-phenyl-1H-pyrazolo[4,3-c]quinolin-3-one;8-fluoro-2-(2-fluorophenyl)-7-(4-methylpiperazin-1-yl)-1H-pyrazolo[4,3-c]quinolin-3-one;8-fluoro-7-morpholin-4-yl-2-thiophen-3-yl-1H-pyrazolo[4,3-c]quinolin-3-one;2-(4-methoxyphenyl)-8-(4-propan-2-ylpiperazin-1-yl)-1H-pyrazolo[4,3-c]quinolin-3-one;2-phenyl-8-piperazin-1-yl-1H-pyrazolo[4,3-c]quinolin-3-one?

The canonical SMILES for 8-(2,6-dimethylmorpholin-4-yl)-2-phenyl-1H-pyrazolo[4,3-c]quinolin-3-one;8-fluoro-2-(2-fluorophenyl)-7-(4-methylpiperazin-1-yl)-1H-pyrazolo[4,3-c]quinolin-3-one;8-fluoro-7-morpholin-4-yl-2-thiophen-3-yl-1H-pyrazolo[4,3-c]quinolin-3-one;2-(4-methoxyphenyl)-8-(4-propan-2-ylpiperazin-1-yl)-1H-pyrazolo[4,3-c]quinolin-3-one;2-phenyl-8-piperazin-1-yl-1H-pyrazolo[4,3-c]quinolin-3-one is CC1CN(c2ccc3ncc4c(=O)n(-c5ccccc5)[nH]c4c3c2)CC(C)O1.CN1CCN(c2cc3ncc4c(=O)n(-c5ccccc5F)[nH]c4c3cc2F)CC1.COc1ccc(-n2[nH]c3c(cnc4ccc(N5CCN(C(C)C)CC5)cc43)c2=O)cc1.O=c1c2cnc3cc(N4CCOCC4)c(F)cc3c2[nH]n1-c1ccsc1.O=c1c2cnc3ccc(N4CCNCC4)cc3c2[nH]n1-c1ccccc1.

What is the InChIKey of 8-(2,6-dimethylmorpholin-4-yl)-2-phenyl-1H-pyrazolo[4,3-c]quinolin-3-one;8-fluoro-2-(2-fluorophenyl)-7-(4-methylpiperazin-1-yl)-1H-pyrazolo[4,3-c]quinolin-3-one;8-fluoro-7-morpholin-4-yl-2-thiophen-3-yl-1H-pyrazolo[4,3-c]quinolin-3-one;2-(4-methoxyphenyl)-8-(4-propan-2-ylpiperazin-1-yl)-1H-pyrazolo[4,3-c]quinolin-3-one;2-phenyl-8-piperazin-1-yl-1H-pyrazolo[4,3-c]quinolin-3-one?

The InChIKey is ZDXSDTWPHRUDSJ-UHFFFAOYSA-N. The full InChI is InChI=1S/C24H27N5O2.C22H22N4O2.C21H19F2N5O.C20H19N5O.C18H15FN4O2S/c1-16(2)27-10-12-28(13-11-27)18-6-9-22-20(14-18)23-21(15-25-22)24(30)29(26-23)17-4-7-19(31-3)8-5-17;1-14-12-25(13-15(2)28-14)17-8-9-20-18(10-17)21-19(11-23-20)22(27)26(24-21)16-6-4-3-5-7-16;1-26-6-8-27(9-7-26)19-11-17-13(10-16(19)23)20-14(12-24-17)21(29)28(25-20)18-5-3-2-4-15(18)22;26-20-17-13-22-18-7-6-15(24-10-8-21-9-11-24)12-16(18)19(17)23-25(20)14-4-2-1-3-5-14;19-14-7-12-15(8-16(14)22-2-4-25-5-3-22)20-9-13-17(12)21-23(18(13)24)11-1-6-26-10-11/h4-9,14-16,26H,10-13H2,1-3H3;3-11,14-15,24H,12-13H2,1-2H3;2-5,10-12,25H,6-9H2,1H3;1-7,12-13,21,23H,8-11H2;1,6-10,21H,2-5H2.

What are the key properties of 8-(2,6-dimethylmorpholin-4-yl)-2-phenyl-1H-pyrazolo[4,3-c]quinolin-3-one;8-fluoro-2-(2-fluorophenyl)-7-(4-methylpiperazin-1-yl)-1H-pyrazolo[4,3-c]quinolin-3-one;8-fluoro-7-morpholin-4-yl-2-thiophen-3-yl-1H-pyrazolo[4,3-c]quinolin-3-one;2-(4-methoxyphenyl)-8-(4-propan-2-ylpiperazin-1-yl)-1H-pyrazolo[4,3-c]quinolin-3-one;2-phenyl-8-piperazin-1-yl-1H-pyrazolo[4,3-c]quinolin-3-one?

8-(2,6-dimethylmorpholin-4-yl)-2-phenyl-1H-pyrazolo[4,3-c]quinolin-3-one;8-fluoro-2-(2-fluorophenyl)-7-(4-methylpiperazin-1-yl)-1H-pyrazolo[4,3-c]quinolin-3-one;8-fluoro-7-morpholin-4-yl-2-thiophen-3-yl-1H-pyrazolo[4,3-c]quinolin-3-one;2-(4-methoxyphenyl)-8-(4-propan-2-ylpiperazin-1-yl)-1H-pyrazolo[4,3-c]quinolin-3-one;2-phenyl-8-piperazin-1-yl-1H-pyrazolo[4,3-c]quinolin-3-one has a molecular weight of 1903.18 g/mol, XLogP of 14.96, 12 rotatable bonds, 6 hydrogen bond donors, and 27 hydrogen bond acceptors.

Where does this data come from?

All data for 8-(2,6-dimethylmorpholin-4-yl)-2-phenyl-1H-pyrazolo[4,3-c]quinolin-3-one;8-fluoro-2-(2-fluorophenyl)-7-(4-methylpiperazin-1-yl)-1H-pyrazolo[4,3-c]quinolin-3-one;8-fluoro-7-morpholin-4-yl-2-thiophen-3-yl-1H-pyrazolo[4,3-c]quinolin-3-one;2-(4-methoxyphenyl)-8-(4-propan-2-ylpiperazin-1-yl)-1H-pyrazolo[4,3-c]quinolin-3-one;2-phenyl-8-piperazin-1-yl-1H-pyrazolo[4,3-c]quinolin-3-one is sourced from PubChem (CID 159105415), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).