N-[1-[2-(4-methylpiperazin-1-yl)ethyl]-3-pyridin-2-ylpyrazol-4-yl]-5-(1H-pyrazol-4-yl)furan-2-carboxamide;N-[1-(2-morpholin-4-ylethyl)-3-pyridin-2-ylpyrazol-4-yl]-5-(1H-pyrazol-4-yl)furan-2-carboxamide;N-(1-propan-2-yl-3-pyridin-2-ylpyrazol-4-yl)-5-(1H-pyrazol-4-yl)furan-2-carboxamide;5-(1H-pyrazol-4-yl)-N-[3-pyridin-2-yl-1-[2-(2,2,2-trifluoroethoxy)ethyl]pyrazol-4-yl]furan-2-carboxamide

C84H84F3N27O10 — CID 159133752

About N-[1-[2-(4-methylpiperazin-1-yl)ethyl]-3-pyridin-2-ylpyrazol-4-yl]-5-(1H-pyrazol-4-yl)furan-2-carboxamide;N-[1-(2-morpholin-4-ylethyl)-3-pyridin-2-ylpyrazol-4-yl]-5-(1H-pyrazol-4-yl)furan-2-carboxamide;N-(1-propan-2-yl-3-pyridin-2-ylpyrazol-4-yl)-5-(1H-pyrazol-4-yl)furan-2-carboxamide;5-(1H-pyrazol-4-yl)-N-[3-pyridin-2-yl-1-[2-(2,2,2-trifluoroethoxy)ethyl]pyrazol-4-yl]furan-2-carboxamide

N-[1-[2-(4-methylpiperazin-1-yl)ethyl]-3-pyridin-2-ylpyrazol-4-yl]-5-(1H-pyrazol-4-yl)furan-2-carboxamide;N-[1-(2-morpholin-4-ylethyl)-3-pyridin-2-ylpyrazol-4-yl]-5-(1H-pyrazol-4-yl)furan-2-carboxamide;N-(1-propan-2-yl-3-pyridin-2-ylpyrazol-4-yl)-5-(1H-pyrazol-4-yl)furan-2-carboxamide;5-(1H-pyrazol-4-yl)-N-[3-pyridin-2-yl-1-[2-(2,2,2-trifluoroethoxy)ethyl]pyrazol-4-yl]furan-2-carboxamide (PubChem CID 159133752) has the molecular formula C84H84F3N27O10 and a molecular weight of 1688.77 g/mol. Its IUPAC name is N-[1-[2-(4-methylpiperazin-1-yl)ethyl]-3-pyridin-2-ylpyrazol-4-yl]-5-(1H-pyrazol-4-yl)furan-2-carboxamide;N-[1-(2-morpholin-4-ylethyl)-3-pyridin-2-ylpyrazol-4-yl]-5-(1H-pyrazol-4-yl)furan-2-carboxamide;N-(1-propan-2-yl-3-pyridin-2-ylpyrazol-4-yl)-5-(1H-pyrazol-4-yl)furan-2-carboxamide;5-(1H-pyrazol-4-yl)-N-[3-pyridin-2-yl-1-[2-(2,2,2-trifluoroethoxy)ethyl]pyrazol-4-yl]furan-2-carboxamide.

Molecular Properties

• Compound Name: N-[1-[2-(4-methylpiperazin-1-yl)ethyl]-3-pyridin-2-ylpyrazol-4-yl]-5-(1H-pyrazol-4-yl)furan-2-carboxamide;N-[1-(2-morpholin-4-ylethyl)-3-pyridin-2-ylpyrazol-4-yl]-5-(1H-pyrazol-4-yl)furan-2-carboxamide;N-(1-propan-2-yl-3-pyridin-2-ylpyrazol-4-yl)-5-(1H-pyrazol-4-yl)furan-2-carboxamide;5-(1H-pyrazol-4-yl)-N-[3-pyridin-2-yl-1-[2-(2,2,2-trifluoroethoxy)ethyl]pyrazol-4-yl]furan-2-carboxamide
• PubChem CID: 159133752
• Molecular Formula: C84H84F3N27O10
• Molecular Weight: 1688.77 g/mol
• Exact Mass: 1687.68
• IUPAC Name: N-[1-[2-(4-methylpiperazin-1-yl)ethyl]-3-pyridin-2-ylpyrazol-4-yl]-5-(1H-pyrazol-4-yl)furan-2-carboxamide;N-[1-(2-morpholin-4-ylethyl)-3-pyridin-2-ylpyrazol-4-yl]-5-(1H-pyrazol-4-yl)furan-2-carboxamide;N-(1-propan-2-yl-3-pyridin-2-ylpyrazol-4-yl)-5-(1H-pyrazol-4-yl)furan-2-carboxamide;5-(1H-pyrazol-4-yl)-N-[3-pyridin-2-yl-1-[2-(2,2,2-trifluoroethoxy)ethyl]pyrazol-4-yl]furan-2-carboxamide
• SMILES: CC(C)n1cc(NC(=O)c2ccc(-c3cn[nH]c3)o2)c(-c2ccccn2)n1.CN1CCN(CCn2cc(NC(=O)c3ccc(-c4cn[nH]c4)o3)c(-c3ccccn3)n2)CC1.O=C(Nc1cn(CCN2CCOCC2)nc1-c1ccccn1)c1ccc(-c2cn[nH]c2)o1.O=C(Nc1cn(CCOCC(F)(F)F)nc1-c1ccccn1)c1ccc(-c2cn[nH]c2)o1
• InChI: InChI=1S/C23H26N8O2.C22H23N7O3.C20H17F3N6O3.C19H18N6O2/c1-29-8-10-30(11-9-29)12-13-31-16-19(22(28-31)18-4-2-3-7-24-18)27-23(32)21-6-5-20(33-21)17-14-25-26-15-17;30-22(20-5-4-19(32-20)16-13-24-25-14-16)26-18-15-29(8-7-28-9-11-31-12-10-28)27-21(18)17-3-1-2-6-23-17;21-20(22,23)12-31-8-7-29-11-15(18(28-29)14-3-1-2-6-24-14)27-19(30)17-5-4-16(32-17)13-9-25-26-10-13;1-12(2)25-11-15(18(24-25)14-5-3-4-8-20-14)23-19(26)17-7-6-16(27-17)13-9-21-22-10-13/h2-7,14-16H,8-13H2,1H3,(H,25,26)(H,27,32);1-6,13-15H,7-12H2,(H,24,25)(H,26,30);1-6,9-11H,7-8,12H2,(H,25,26)(H,27,30);3-12H,1-2H3,(H,21,22)(H,23,26)
• InChIKey: KHFJZJVEXVNCGX-UHFFFAOYSA-N
• XLogP: 12.46
• TPSA: 434.70 Ų
• H-Bond Donors: 8
• H-Bond Acceptors: 29
• Rotatable Bonds: 27
• Heavy Atoms: 124
• Complexity: —

Lipinski Rule of Five

4 violations

Rule	Value
MW ≤ 500	1688.77
LogP ≤ 5	12.46
H-Bond Donors ≤ 5	8
H-Bond Acceptors ≤ 10	29

Computed Properties (RDKit)

• Structural Alerts: {'alert_name': 'Aliphatic_long_chain', 'substructure': 'N/A'}

Frequently Asked Questions

What is the IUPAC name of N-[1-[2-(4-methylpiperazin-1-yl)ethyl]-3-pyridin-2-ylpyrazol-4-yl]-5-(1H-pyrazol-4-yl)furan-2-carboxamide;N-[1-(2-morpholin-4-ylethyl)-3-pyridin-2-ylpyrazol-4-yl]-5-(1H-pyrazol-4-yl)furan-2-carboxamide;N-(1-propan-2-yl-3-pyridin-2-ylpyrazol-4-yl)-5-(1H-pyrazol-4-yl)furan-2-carboxamide;5-(1H-pyrazol-4-yl)-N-[3-pyridin-2-yl-1-[2-(2,2,2-trifluoroethoxy)ethyl]pyrazol-4-yl]furan-2-carboxamide?

The IUPAC name of N-[1-[2-(4-methylpiperazin-1-yl)ethyl]-3-pyridin-2-ylpyrazol-4-yl]-5-(1H-pyrazol-4-yl)furan-2-carboxamide;N-[1-(2-morpholin-4-ylethyl)-3-pyridin-2-ylpyrazol-4-yl]-5-(1H-pyrazol-4-yl)furan-2-carboxamide;N-(1-propan-2-yl-3-pyridin-2-ylpyrazol-4-yl)-5-(1H-pyrazol-4-yl)furan-2-carboxamide;5-(1H-pyrazol-4-yl)-N-[3-pyridin-2-yl-1-[2-(2,2,2-trifluoroethoxy)ethyl]pyrazol-4-yl]furan-2-carboxamide (CID 159133752) is N-[1-[2-(4-methylpiperazin-1-yl)ethyl]-3-pyridin-2-ylpyrazol-4-yl]-5-(1H-pyrazol-4-yl)furan-2-carboxamide;N-[1-(2-morpholin-4-ylethyl)-3-pyridin-2-ylpyrazol-4-yl]-5-(1H-pyrazol-4-yl)furan-2-carboxamide;N-(1-propan-2-yl-3-pyridin-2-ylpyrazol-4-yl)-5-(1H-pyrazol-4-yl)furan-2-carboxamide;5-(1H-pyrazol-4-yl)-N-[3-pyridin-2-yl-1-[2-(2,2,2-trifluoroethoxy)ethyl]pyrazol-4-yl]furan-2-carboxamide.

What is the SMILES notation for N-[1-[2-(4-methylpiperazin-1-yl)ethyl]-3-pyridin-2-ylpyrazol-4-yl]-5-(1H-pyrazol-4-yl)furan-2-carboxamide;N-[1-(2-morpholin-4-ylethyl)-3-pyridin-2-ylpyrazol-4-yl]-5-(1H-pyrazol-4-yl)furan-2-carboxamide;N-(1-propan-2-yl-3-pyridin-2-ylpyrazol-4-yl)-5-(1H-pyrazol-4-yl)furan-2-carboxamide;5-(1H-pyrazol-4-yl)-N-[3-pyridin-2-yl-1-[2-(2,2,2-trifluoroethoxy)ethyl]pyrazol-4-yl]furan-2-carboxamide?

The canonical SMILES for N-[1-[2-(4-methylpiperazin-1-yl)ethyl]-3-pyridin-2-ylpyrazol-4-yl]-5-(1H-pyrazol-4-yl)furan-2-carboxamide;N-[1-(2-morpholin-4-ylethyl)-3-pyridin-2-ylpyrazol-4-yl]-5-(1H-pyrazol-4-yl)furan-2-carboxamide;N-(1-propan-2-yl-3-pyridin-2-ylpyrazol-4-yl)-5-(1H-pyrazol-4-yl)furan-2-carboxamide;5-(1H-pyrazol-4-yl)-N-[3-pyridin-2-yl-1-[2-(2,2,2-trifluoroethoxy)ethyl]pyrazol-4-yl]furan-2-carboxamide is CC(C)n1cc(NC(=O)c2ccc(-c3cn[nH]c3)o2)c(-c2ccccn2)n1.CN1CCN(CCn2cc(NC(=O)c3ccc(-c4cn[nH]c4)o3)c(-c3ccccn3)n2)CC1.O=C(Nc1cn(CCN2CCOCC2)nc1-c1ccccn1)c1ccc(-c2cn[nH]c2)o1.O=C(Nc1cn(CCOCC(F)(F)F)nc1-c1ccccn1)c1ccc(-c2cn[nH]c2)o1.

What is the InChIKey of N-[1-[2-(4-methylpiperazin-1-yl)ethyl]-3-pyridin-2-ylpyrazol-4-yl]-5-(1H-pyrazol-4-yl)furan-2-carboxamide;N-[1-(2-morpholin-4-ylethyl)-3-pyridin-2-ylpyrazol-4-yl]-5-(1H-pyrazol-4-yl)furan-2-carboxamide;N-(1-propan-2-yl-3-pyridin-2-ylpyrazol-4-yl)-5-(1H-pyrazol-4-yl)furan-2-carboxamide;5-(1H-pyrazol-4-yl)-N-[3-pyridin-2-yl-1-[2-(2,2,2-trifluoroethoxy)ethyl]pyrazol-4-yl]furan-2-carboxamide?

The InChIKey is KHFJZJVEXVNCGX-UHFFFAOYSA-N. The full InChI is InChI=1S/C23H26N8O2.C22H23N7O3.C20H17F3N6O3.C19H18N6O2/c1-29-8-10-30(11-9-29)12-13-31-16-19(22(28-31)18-4-2-3-7-24-18)27-23(32)21-6-5-20(33-21)17-14-25-26-15-17;30-22(20-5-4-19(32-20)16-13-24-25-14-16)26-18-15-29(8-7-28-9-11-31-12-10-28)27-21(18)17-3-1-2-6-23-17;21-20(22,23)12-31-8-7-29-11-15(18(28-29)14-3-1-2-6-24-14)27-19(30)17-5-4-16(32-17)13-9-25-26-10-13;1-12(2)25-11-15(18(24-25)14-5-3-4-8-20-14)23-19(26)17-7-6-16(27-17)13-9-21-22-10-13/h2-7,14-16H,8-13H2,1H3,(H,25,26)(H,27,32);1-6,13-15H,7-12H2,(H,24,25)(H,26,30);1-6,9-11H,7-8,12H2,(H,25,26)(H,27,30);3-12H,1-2H3,(H,21,22)(H,23,26).

What are the key properties of N-[1-[2-(4-methylpiperazin-1-yl)ethyl]-3-pyridin-2-ylpyrazol-4-yl]-5-(1H-pyrazol-4-yl)furan-2-carboxamide;N-[1-(2-morpholin-4-ylethyl)-3-pyridin-2-ylpyrazol-4-yl]-5-(1H-pyrazol-4-yl)furan-2-carboxamide;N-(1-propan-2-yl-3-pyridin-2-ylpyrazol-4-yl)-5-(1H-pyrazol-4-yl)furan-2-carboxamide;5-(1H-pyrazol-4-yl)-N-[3-pyridin-2-yl-1-[2-(2,2,2-trifluoroethoxy)ethyl]pyrazol-4-yl]furan-2-carboxamide?

N-[1-[2-(4-methylpiperazin-1-yl)ethyl]-3-pyridin-2-ylpyrazol-4-yl]-5-(1H-pyrazol-4-yl)furan-2-carboxamide;N-[1-(2-morpholin-4-ylethyl)-3-pyridin-2-ylpyrazol-4-yl]-5-(1H-pyrazol-4-yl)furan-2-carboxamide;N-(1-propan-2-yl-3-pyridin-2-ylpyrazol-4-yl)-5-(1H-pyrazol-4-yl)furan-2-carboxamide;5-(1H-pyrazol-4-yl)-N-[3-pyridin-2-yl-1-[2-(2,2,2-trifluoroethoxy)ethyl]pyrazol-4-yl]furan-2-carboxamide has a molecular weight of 1688.77 g/mol, XLogP of 12.46, 27 rotatable bonds, 8 hydrogen bond donors, and 29 hydrogen bond acceptors.

Where does this data come from?

All data for N-[1-[2-(4-methylpiperazin-1-yl)ethyl]-3-pyridin-2-ylpyrazol-4-yl]-5-(1H-pyrazol-4-yl)furan-2-carboxamide;N-[1-(2-morpholin-4-ylethyl)-3-pyridin-2-ylpyrazol-4-yl]-5-(1H-pyrazol-4-yl)furan-2-carboxamide;N-(1-propan-2-yl-3-pyridin-2-ylpyrazol-4-yl)-5-(1H-pyrazol-4-yl)furan-2-carboxamide;5-(1H-pyrazol-4-yl)-N-[3-pyridin-2-yl-1-[2-(2,2,2-trifluoroethoxy)ethyl]pyrazol-4-yl]furan-2-carboxamide is sourced from PubChem (CID 159133752), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).