[6-[5-chloro-6-[(2R)-2-(4-methylphenyl)propyl]pyridazin-3-yl]-3-(4-methylimidazol-1-yl)-2-pyridinyl]methanol;[6-[4-ethyl-6-[methyl-[(1S)-1-(4-methylphenyl)ethyl]amino]pyridazin-3-yl]-3-(4-methylimidazol-1-yl)-2-pyridinyl]methanol;[6-[5-fluoro-6-[(2R)-2-(4-methylphenyl)propyl]pyridazin-3-yl]-3-(4-methylimidazol-1-yl)-2-pyridinyl]methanol;6-[6-(hydroxymethyl)-5-(4-methylimidazol-1-yl)-2-pyridinyl]-3-[(2R)-2-(4-methylphenyl)propyl]pyridazine-4-carbonitrile;[3-(4-methylimidazol-1-yl)-6-[4-[(2R)-2-(4-methylphenyl)propyl]-5,6,7,8-tetrahydrophthalazin-1-yl]-2-pyridinyl]methanol;[3-(4-methylimidazol-1-yl)-6-[6-[(2R)-2-(4-methylphenyl)propyl]-5-(trifluoromethyl)pyridazin-3-yl]-2-pyridinyl]methanol

C152H157ClF4N32O6 — CID 159158260

About [6-[5-chloro-6-[(2R)-2-(4-methylphenyl)propyl]pyridazin-3-yl]-3-(4-methylimidazol-1-yl)-2-pyridinyl]methanol;[6-[4-ethyl-6-[methyl-[(1S)-1-(4-methylphenyl)ethyl]amino]pyridazin-3-yl]-3-(4-methylimidazol-1-yl)-2-pyridinyl]methanol;[6-[5-fluoro-6-[(2R)-2-(4-methylphenyl)propyl]pyridazin-3-yl]-3-(4-methylimidazol-1-yl)-2-pyridinyl]methanol;6-[6-(hydroxymethyl)-5-(4-methylimidazol-1-yl)-2-pyridinyl]-3-[(2R)-2-(4-methylphenyl)propyl]pyridazine-4-carbonitrile;[3-(4-methylimidazol-1-yl)-6-[4-[(2R)-2-(4-methylphenyl)propyl]-5,6,7,8-tetrahydrophthalazin-1-yl]-2-pyridinyl]methanol;[3-(4-methylimidazol-1-yl)-6-[6-[(2R)-2-(4-methylphenyl)propyl]-5-(trifluoromethyl)pyridazin-3-yl]-2-pyridinyl]methanol

[6-[5-chloro-6-[(2R)-2-(4-methylphenyl)propyl]pyridazin-3-yl]-3-(4-methylimidazol-1-yl)-2-pyridinyl]methanol;[6-[4-ethyl-6-[methyl-[(1S)-1-(4-methylphenyl)ethyl]amino]pyridazin-3-yl]-3-(4-methylimidazol-1-yl)-2-pyridinyl]methanol;[6-[5-fluoro-6-[(2R)-2-(4-methylphenyl)propyl]pyridazin-3-yl]-3-(4-methylimidazol-1-yl)-2-pyridinyl]methanol;6-[6-(hydroxymethyl)-5-(4-methylimidazol-1-yl)-2-pyridinyl]-3-[(2R)-2-(4-methylphenyl)propyl]pyridazine-4-carbonitrile;[3-(4-methylimidazol-1-yl)-6-[4-[(2R)-2-(4-methylphenyl)propyl]-5,6,7,8-tetrahydrophthalazin-1-yl]-2-pyridinyl]methanol;[3-(4-methylimidazol-1-yl)-6-[6-[(2R)-2-(4-methylphenyl)propyl]-5-(trifluoromethyl)pyridazin-3-yl]-2-pyridinyl]methanol (PubChem CID 159158260) has the molecular formula C152H157ClF4N32O6 and a molecular weight of 2639.59 g/mol. Its IUPAC name is [6-[5-chloro-6-[(2R)-2-(4-methylphenyl)propyl]pyridazin-3-yl]-3-(4-methylimidazol-1-yl)-2-pyridinyl]methanol;[6-[4-ethyl-6-[methyl-[(1S)-1-(4-methylphenyl)ethyl]amino]pyridazin-3-yl]-3-(4-methylimidazol-1-yl)-2-pyridinyl]methanol;[6-[5-fluoro-6-[(2R)-2-(4-methylphenyl)propyl]pyridazin-3-yl]-3-(4-methylimidazol-1-yl)-2-pyridinyl]methanol;6-[6-(hydroxymethyl)-5-(4-methylimidazol-1-yl)-2-pyridinyl]-3-[(2R)-2-(4-methylphenyl)propyl]pyridazine-4-carbonitrile;[3-(4-methylimidazol-1-yl)-6-[4-[(2R)-2-(4-methylphenyl)propyl]-5,6,7,8-tetrahydrophthalazin-1-yl]-2-pyridinyl]methanol;[3-(4-methylimidazol-1-yl)-6-[6-[(2R)-2-(4-methylphenyl)propyl]-5-(trifluoromethyl)pyridazin-3-yl]-2-pyridinyl]methanol.

Molecular Properties

• Compound Name: [6-[5-chloro-6-[(2R)-2-(4-methylphenyl)propyl]pyridazin-3-yl]-3-(4-methylimidazol-1-yl)-2-pyridinyl]methanol;[6-[4-ethyl-6-[methyl-[(1S)-1-(4-methylphenyl)ethyl]amino]pyridazin-3-yl]-3-(4-methylimidazol-1-yl)-2-pyridinyl]methanol;[6-[5-fluoro-6-[(2R)-2-(4-methylphenyl)propyl]pyridazin-3-yl]-3-(4-methylimidazol-1-yl)-2-pyridinyl]methanol;6-[6-(hydroxymethyl)-5-(4-methylimidazol-1-yl)-2-pyridinyl]-3-[(2R)-2-(4-methylphenyl)propyl]pyridazine-4-carbonitrile;[3-(4-methylimidazol-1-yl)-6-[4-[(2R)-2-(4-methylphenyl)propyl]-5,6,7,8-tetrahydrophthalazin-1-yl]-2-pyridinyl]methanol;[3-(4-methylimidazol-1-yl)-6-[6-[(2R)-2-(4-methylphenyl)propyl]-5-(trifluoromethyl)pyridazin-3-yl]-2-pyridinyl]methanol
• PubChem CID: 159158260
• Molecular Formula: C152H157ClF4N32O6
• Molecular Weight: 2639.59 g/mol
• Exact Mass: 2637.26
• IUPAC Name: [6-[5-chloro-6-[(2R)-2-(4-methylphenyl)propyl]pyridazin-3-yl]-3-(4-methylimidazol-1-yl)-2-pyridinyl]methanol;[6-[4-ethyl-6-[methyl-[(1S)-1-(4-methylphenyl)ethyl]amino]pyridazin-3-yl]-3-(4-methylimidazol-1-yl)-2-pyridinyl]methanol;[6-[5-fluoro-6-[(2R)-2-(4-methylphenyl)propyl]pyridazin-3-yl]-3-(4-methylimidazol-1-yl)-2-pyridinyl]methanol;6-[6-(hydroxymethyl)-5-(4-methylimidazol-1-yl)-2-pyridinyl]-3-[(2R)-2-(4-methylphenyl)propyl]pyridazine-4-carbonitrile;[3-(4-methylimidazol-1-yl)-6-[4-[(2R)-2-(4-methylphenyl)propyl]-5,6,7,8-tetrahydrophthalazin-1-yl]-2-pyridinyl]methanol;[3-(4-methylimidazol-1-yl)-6-[6-[(2R)-2-(4-methylphenyl)propyl]-5-(trifluoromethyl)pyridazin-3-yl]-2-pyridinyl]methanol
• SMILES: CCc1cc(N(C)[C@@H](C)c2ccc(C)cc2)nnc1-c1ccc(-n2cnc(C)c2)c(CO)n1.Cc1ccc([C@H](C)Cc2nnc(-c3ccc(-n4cnc(C)c4)c(CO)n3)c3c2CCCC3)cc1.Cc1ccc([C@H](C)Cc2nnc(-c3ccc(-n4cnc(C)c4)c(CO)n3)cc2C#N)cc1.Cc1ccc([C@H](C)Cc2nnc(-c3ccc(-n4cnc(C)c4)c(CO)n3)cc2C(F)(F)F)cc1.Cc1ccc([C@H](C)Cc2nnc(-c3ccc(-n4cnc(C)c4)c(CO)n3)cc2Cl)cc1.Cc1ccc([C@H](C)Cc2nnc(-c3ccc(-n4cnc(C)c4)c(CO)n3)cc2F)cc1
• InChI: InChI=1S/C28H31N5O.C26H30N6O.C25H24F3N5O.C25H24N6O.C24H24ClN5O.C24H24FN5O/c1-18-8-10-21(11-9-18)19(2)14-25-22-6-4-5-7-23(22)28(32-31-25)24-12-13-27(26(16-34)30-24)33-15-20(3)29-17-33;1-6-20-13-25(31(5)19(4)21-9-7-17(2)8-10-21)29-30-26(20)22-11-12-24(23(15-33)28-22)32-14-18(3)27-16-32;1-15-4-6-18(7-5-15)16(2)10-21-19(25(26,27)28)11-22(32-31-21)20-8-9-24(23(13-34)30-20)33-12-17(3)29-14-33;1-16-4-6-19(7-5-16)17(2)10-22-20(12-26)11-23(30-29-22)21-8-9-25(24(14-32)28-21)31-13-18(3)27-15-31;2*1-15-4-6-18(7-5-15)16(2)10-21-19(25)11-22(29-28-21)20-8-9-24(23(13-31)27-20)30-12-17(3)26-14-30/h8-13,15,17,19,34H,4-7,14,16H2,1-3H3;7-14,16,19,33H,6,15H2,1-5H3;4-9,11-12,14,16,34H,10,13H2,1-3H3;4-9,11,13,15,17,32H,10,14H2,1-3H3;2*4-9,11-12,14,16,31H,10,13H2,1-3H3/t2*19-;16-;17-;2*16-/m101111/s1
• InChIKey: KKDYOPRTAQSTGN-BFYNJKTLSA-N
• XLogP: 28.05
• TPSA: 487.35 Ų
• H-Bond Donors: 6
• H-Bond Acceptors: 38
• Rotatable Bonds: 37
• Heavy Atoms: 195
• Complexity: —

Lipinski Rule of Five

4 violations

Rule	Value
MW ≤ 500	2639.59
LogP ≤ 5	28.05
H-Bond Donors ≤ 5	6
H-Bond Acceptors ≤ 10	38

Frequently Asked Questions

What is the IUPAC name of [6-[5-chloro-6-[(2R)-2-(4-methylphenyl)propyl]pyridazin-3-yl]-3-(4-methylimidazol-1-yl)-2-pyridinyl]methanol;[6-[4-ethyl-6-[methyl-[(1S)-1-(4-methylphenyl)ethyl]amino]pyridazin-3-yl]-3-(4-methylimidazol-1-yl)-2-pyridinyl]methanol;[6-[5-fluoro-6-[(2R)-2-(4-methylphenyl)propyl]pyridazin-3-yl]-3-(4-methylimidazol-1-yl)-2-pyridinyl]methanol;6-[6-(hydroxymethyl)-5-(4-methylimidazol-1-yl)-2-pyridinyl]-3-[(2R)-2-(4-methylphenyl)propyl]pyridazine-4-carbonitrile;[3-(4-methylimidazol-1-yl)-6-[4-[(2R)-2-(4-methylphenyl)propyl]-5,6,7,8-tetrahydrophthalazin-1-yl]-2-pyridinyl]methanol;[3-(4-methylimidazol-1-yl)-6-[6-[(2R)-2-(4-methylphenyl)propyl]-5-(trifluoromethyl)pyridazin-3-yl]-2-pyridinyl]methanol?

The IUPAC name of [6-[5-chloro-6-[(2R)-2-(4-methylphenyl)propyl]pyridazin-3-yl]-3-(4-methylimidazol-1-yl)-2-pyridinyl]methanol;[6-[4-ethyl-6-[methyl-[(1S)-1-(4-methylphenyl)ethyl]amino]pyridazin-3-yl]-3-(4-methylimidazol-1-yl)-2-pyridinyl]methanol;[6-[5-fluoro-6-[(2R)-2-(4-methylphenyl)propyl]pyridazin-3-yl]-3-(4-methylimidazol-1-yl)-2-pyridinyl]methanol;6-[6-(hydroxymethyl)-5-(4-methylimidazol-1-yl)-2-pyridinyl]-3-[(2R)-2-(4-methylphenyl)propyl]pyridazine-4-carbonitrile;[3-(4-methylimidazol-1-yl)-6-[4-[(2R)-2-(4-methylphenyl)propyl]-5,6,7,8-tetrahydrophthalazin-1-yl]-2-pyridinyl]methanol;[3-(4-methylimidazol-1-yl)-6-[6-[(2R)-2-(4-methylphenyl)propyl]-5-(trifluoromethyl)pyridazin-3-yl]-2-pyridinyl]methanol (CID 159158260) is [6-[5-chloro-6-[(2R)-2-(4-methylphenyl)propyl]pyridazin-3-yl]-3-(4-methylimidazol-1-yl)-2-pyridinyl]methanol;[6-[4-ethyl-6-[methyl-[(1S)-1-(4-methylphenyl)ethyl]amino]pyridazin-3-yl]-3-(4-methylimidazol-1-yl)-2-pyridinyl]methanol;[6-[5-fluoro-6-[(2R)-2-(4-methylphenyl)propyl]pyridazin-3-yl]-3-(4-methylimidazol-1-yl)-2-pyridinyl]methanol;6-[6-(hydroxymethyl)-5-(4-methylimidazol-1-yl)-2-pyridinyl]-3-[(2R)-2-(4-methylphenyl)propyl]pyridazine-4-carbonitrile;[3-(4-methylimidazol-1-yl)-6-[4-[(2R)-2-(4-methylphenyl)propyl]-5,6,7,8-tetrahydrophthalazin-1-yl]-2-pyridinyl]methanol;[3-(4-methylimidazol-1-yl)-6-[6-[(2R)-2-(4-methylphenyl)propyl]-5-(trifluoromethyl)pyridazin-3-yl]-2-pyridinyl]methanol.

What is the SMILES notation for [6-[5-chloro-6-[(2R)-2-(4-methylphenyl)propyl]pyridazin-3-yl]-3-(4-methylimidazol-1-yl)-2-pyridinyl]methanol;[6-[4-ethyl-6-[methyl-[(1S)-1-(4-methylphenyl)ethyl]amino]pyridazin-3-yl]-3-(4-methylimidazol-1-yl)-2-pyridinyl]methanol;[6-[5-fluoro-6-[(2R)-2-(4-methylphenyl)propyl]pyridazin-3-yl]-3-(4-methylimidazol-1-yl)-2-pyridinyl]methanol;6-[6-(hydroxymethyl)-5-(4-methylimidazol-1-yl)-2-pyridinyl]-3-[(2R)-2-(4-methylphenyl)propyl]pyridazine-4-carbonitrile;[3-(4-methylimidazol-1-yl)-6-[4-[(2R)-2-(4-methylphenyl)propyl]-5,6,7,8-tetrahydrophthalazin-1-yl]-2-pyridinyl]methanol;[3-(4-methylimidazol-1-yl)-6-[6-[(2R)-2-(4-methylphenyl)propyl]-5-(trifluoromethyl)pyridazin-3-yl]-2-pyridinyl]methanol?

The canonical SMILES for [6-[5-chloro-6-[(2R)-2-(4-methylphenyl)propyl]pyridazin-3-yl]-3-(4-methylimidazol-1-yl)-2-pyridinyl]methanol;[6-[4-ethyl-6-[methyl-[(1S)-1-(4-methylphenyl)ethyl]amino]pyridazin-3-yl]-3-(4-methylimidazol-1-yl)-2-pyridinyl]methanol;[6-[5-fluoro-6-[(2R)-2-(4-methylphenyl)propyl]pyridazin-3-yl]-3-(4-methylimidazol-1-yl)-2-pyridinyl]methanol;6-[6-(hydroxymethyl)-5-(4-methylimidazol-1-yl)-2-pyridinyl]-3-[(2R)-2-(4-methylphenyl)propyl]pyridazine-4-carbonitrile;[3-(4-methylimidazol-1-yl)-6-[4-[(2R)-2-(4-methylphenyl)propyl]-5,6,7,8-tetrahydrophthalazin-1-yl]-2-pyridinyl]methanol;[3-(4-methylimidazol-1-yl)-6-[6-[(2R)-2-(4-methylphenyl)propyl]-5-(trifluoromethyl)pyridazin-3-yl]-2-pyridinyl]methanol is CCc1cc(N(C)[C@@H](C)c2ccc(C)cc2)nnc1-c1ccc(-n2cnc(C)c2)c(CO)n1.Cc1ccc([C@H](C)Cc2nnc(-c3ccc(-n4cnc(C)c4)c(CO)n3)c3c2CCCC3)cc1.Cc1ccc([C@H](C)Cc2nnc(-c3ccc(-n4cnc(C)c4)c(CO)n3)cc2C#N)cc1.Cc1ccc([C@H](C)Cc2nnc(-c3ccc(-n4cnc(C)c4)c(CO)n3)cc2C(F)(F)F)cc1.Cc1ccc([C@H](C)Cc2nnc(-c3ccc(-n4cnc(C)c4)c(CO)n3)cc2Cl)cc1.Cc1ccc([C@H](C)Cc2nnc(-c3ccc(-n4cnc(C)c4)c(CO)n3)cc2F)cc1.

What is the InChIKey of [6-[5-chloro-6-[(2R)-2-(4-methylphenyl)propyl]pyridazin-3-yl]-3-(4-methylimidazol-1-yl)-2-pyridinyl]methanol;[6-[4-ethyl-6-[methyl-[(1S)-1-(4-methylphenyl)ethyl]amino]pyridazin-3-yl]-3-(4-methylimidazol-1-yl)-2-pyridinyl]methanol;[6-[5-fluoro-6-[(2R)-2-(4-methylphenyl)propyl]pyridazin-3-yl]-3-(4-methylimidazol-1-yl)-2-pyridinyl]methanol;6-[6-(hydroxymethyl)-5-(4-methylimidazol-1-yl)-2-pyridinyl]-3-[(2R)-2-(4-methylphenyl)propyl]pyridazine-4-carbonitrile;[3-(4-methylimidazol-1-yl)-6-[4-[(2R)-2-(4-methylphenyl)propyl]-5,6,7,8-tetrahydrophthalazin-1-yl]-2-pyridinyl]methanol;[3-(4-methylimidazol-1-yl)-6-[6-[(2R)-2-(4-methylphenyl)propyl]-5-(trifluoromethyl)pyridazin-3-yl]-2-pyridinyl]methanol?

The InChIKey is KKDYOPRTAQSTGN-BFYNJKTLSA-N. The full InChI is InChI=1S/C28H31N5O.C26H30N6O.C25H24F3N5O.C25H24N6O.C24H24ClN5O.C24H24FN5O/c1-18-8-10-21(11-9-18)19(2)14-25-22-6-4-5-7-23(22)28(32-31-25)24-12-13-27(26(16-34)30-24)33-15-20(3)29-17-33;1-6-20-13-25(31(5)19(4)21-9-7-17(2)8-10-21)29-30-26(20)22-11-12-24(23(15-33)28-22)32-14-18(3)27-16-32;1-15-4-6-18(7-5-15)16(2)10-21-19(25(26,27)28)11-22(32-31-21)20-8-9-24(23(13-34)30-20)33-12-17(3)29-14-33;1-16-4-6-19(7-5-16)17(2)10-22-20(12-26)11-23(30-29-22)21-8-9-25(24(14-32)28-21)31-13-18(3)27-15-31;2*1-15-4-6-18(7-5-15)16(2)10-21-19(25)11-22(29-28-21)20-8-9-24(23(13-31)27-20)30-12-17(3)26-14-30/h8-13,15,17,19,34H,4-7,14,16H2,1-3H3;7-14,16,19,33H,6,15H2,1-5H3;4-9,11-12,14,16,34H,10,13H2,1-3H3;4-9,11,13,15,17,32H,10,14H2,1-3H3;2*4-9,11-12,14,16,31H,10,13H2,1-3H3/t2*19-;16-;17-;2*16-/m101111/s1.

What are the key properties of [6-[5-chloro-6-[(2R)-2-(4-methylphenyl)propyl]pyridazin-3-yl]-3-(4-methylimidazol-1-yl)-2-pyridinyl]methanol;[6-[4-ethyl-6-[methyl-[(1S)-1-(4-methylphenyl)ethyl]amino]pyridazin-3-yl]-3-(4-methylimidazol-1-yl)-2-pyridinyl]methanol;[6-[5-fluoro-6-[(2R)-2-(4-methylphenyl)propyl]pyridazin-3-yl]-3-(4-methylimidazol-1-yl)-2-pyridinyl]methanol;6-[6-(hydroxymethyl)-5-(4-methylimidazol-1-yl)-2-pyridinyl]-3-[(2R)-2-(4-methylphenyl)propyl]pyridazine-4-carbonitrile;[3-(4-methylimidazol-1-yl)-6-[4-[(2R)-2-(4-methylphenyl)propyl]-5,6,7,8-tetrahydrophthalazin-1-yl]-2-pyridinyl]methanol;[3-(4-methylimidazol-1-yl)-6-[6-[(2R)-2-(4-methylphenyl)propyl]-5-(trifluoromethyl)pyridazin-3-yl]-2-pyridinyl]methanol?

[6-[5-chloro-6-[(2R)-2-(4-methylphenyl)propyl]pyridazin-3-yl]-3-(4-methylimidazol-1-yl)-2-pyridinyl]methanol;[6-[4-ethyl-6-[methyl-[(1S)-1-(4-methylphenyl)ethyl]amino]pyridazin-3-yl]-3-(4-methylimidazol-1-yl)-2-pyridinyl]methanol;[6-[5-fluoro-6-[(2R)-2-(4-methylphenyl)propyl]pyridazin-3-yl]-3-(4-methylimidazol-1-yl)-2-pyridinyl]methanol;6-[6-(hydroxymethyl)-5-(4-methylimidazol-1-yl)-2-pyridinyl]-3-[(2R)-2-(4-methylphenyl)propyl]pyridazine-4-carbonitrile;[3-(4-methylimidazol-1-yl)-6-[4-[(2R)-2-(4-methylphenyl)propyl]-5,6,7,8-tetrahydrophthalazin-1-yl]-2-pyridinyl]methanol;[3-(4-methylimidazol-1-yl)-6-[6-[(2R)-2-(4-methylphenyl)propyl]-5-(trifluoromethyl)pyridazin-3-yl]-2-pyridinyl]methanol has a molecular weight of 2639.59 g/mol, XLogP of 28.05, 37 rotatable bonds, 6 hydrogen bond donors, and 38 hydrogen bond acceptors.

Where does this data come from?

All data for [6-[5-chloro-6-[(2R)-2-(4-methylphenyl)propyl]pyridazin-3-yl]-3-(4-methylimidazol-1-yl)-2-pyridinyl]methanol;[6-[4-ethyl-6-[methyl-[(1S)-1-(4-methylphenyl)ethyl]amino]pyridazin-3-yl]-3-(4-methylimidazol-1-yl)-2-pyridinyl]methanol;[6-[5-fluoro-6-[(2R)-2-(4-methylphenyl)propyl]pyridazin-3-yl]-3-(4-methylimidazol-1-yl)-2-pyridinyl]methanol;6-[6-(hydroxymethyl)-5-(4-methylimidazol-1-yl)-2-pyridinyl]-3-[(2R)-2-(4-methylphenyl)propyl]pyridazine-4-carbonitrile;[3-(4-methylimidazol-1-yl)-6-[4-[(2R)-2-(4-methylphenyl)propyl]-5,6,7,8-tetrahydrophthalazin-1-yl]-2-pyridinyl]methanol;[3-(4-methylimidazol-1-yl)-6-[6-[(2R)-2-(4-methylphenyl)propyl]-5-(trifluoromethyl)pyridazin-3-yl]-2-pyridinyl]methanol is sourced from PubChem (CID 159158260), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).