N-[(1R,3R)-3-[[5-cyano-3-fluoro-6-(7H-pyrrolo[2,3-d]pyrimidin-5-yl)-2-pyridinyl]amino]cyclohexyl]-1-methylimidazole-4-carboxamide;N-[(1S,3R)-3-[[3,5-difluoro-6-(7H-pyrrolo[2,3-d]pyrimidin-5-yl)-2-pyridinyl]amino]cyclohexyl]-1-methylimidazole-4-carboxamide;5-[5-fluoro-4-[[(1R,3S)-3-(2-pyridin-4-ylprop-2-enyl)cyclohexyl]methyl]pyrimidin-2-yl]-7H-pyrrolo[2,3-d]pyrimidine;N-[(1R,3R)-3-[[5-fluoro-2-(7H-pyrrolo[2,3-d]pyrimidin-5-yl)pyrimidin-4-yl]amino]cyclohexyl]-5-methyl-1,2-oxazole-3-carboxamide;N-[(1S,3R)-3-[[5-fluoro-2-(7H-pyrrolo[2,3-d]pyrimidin-5-yl)pyrimidin-4-yl]methyl]cyclohexyl]-1-methylimidazole-4-carboxamide;2-[(1S,3R)-3-[[5-fluoro-2-(7H-pyrrolo[2,3-d]pyrimidin-5-yl)pyrimidin-4-yl]methyl]cyclohexyl]-1-(3-methyl-1,2-oxazol-5-yl)ethanone

C136H136F7N45O7 — CID 159165744

About N-[(1R,3R)-3-[[5-cyano-3-fluoro-6-(7H-pyrrolo[2,3-d]pyrimidin-5-yl)-2-pyridinyl]amino]cyclohexyl]-1-methylimidazole-4-carboxamide;N-[(1S,3R)-3-[[3,5-difluoro-6-(7H-pyrrolo[2,3-d]pyrimidin-5-yl)-2-pyridinyl]amino]cyclohexyl]-1-methylimidazole-4-carboxamide;5-[5-fluoro-4-[[(1R,3S)-3-(2-pyridin-4-ylprop-2-enyl)cyclohexyl]methyl]pyrimidin-2-yl]-7H-pyrrolo[2,3-d]pyrimidine;N-[(1R,3R)-3-[[5-fluoro-2-(7H-pyrrolo[2,3-d]pyrimidin-5-yl)pyrimidin-4-yl]amino]cyclohexyl]-5-methyl-1,2-oxazole-3-carboxamide;N-[(1S,3R)-3-[[5-fluoro-2-(7H-pyrrolo[2,3-d]pyrimidin-5-yl)pyrimidin-4-yl]methyl]cyclohexyl]-1-methylimidazole-4-carboxamide;2-[(1S,3R)-3-[[5-fluoro-2-(7H-pyrrolo[2,3-d]pyrimidin-5-yl)pyrimidin-4-yl]methyl]cyclohexyl]-1-(3-methyl-1,2-oxazol-5-yl)ethanone

N-[(1R,3R)-3-[[5-cyano-3-fluoro-6-(7H-pyrrolo[2,3-d]pyrimidin-5-yl)-2-pyridinyl]amino]cyclohexyl]-1-methylimidazole-4-carboxamide;N-[(1S,3R)-3-[[3,5-difluoro-6-(7H-pyrrolo[2,3-d]pyrimidin-5-yl)-2-pyridinyl]amino]cyclohexyl]-1-methylimidazole-4-carboxamide;5-[5-fluoro-4-[[(1R,3S)-3-(2-pyridin-4-ylprop-2-enyl)cyclohexyl]methyl]pyrimidin-2-yl]-7H-pyrrolo[2,3-d]pyrimidine;N-[(1R,3R)-3-[[5-fluoro-2-(7H-pyrrolo[2,3-d]pyrimidin-5-yl)pyrimidin-4-yl]amino]cyclohexyl]-5-methyl-1,2-oxazole-3-carboxamide;N-[(1S,3R)-3-[[5-fluoro-2-(7H-pyrrolo[2,3-d]pyrimidin-5-yl)pyrimidin-4-yl]methyl]cyclohexyl]-1-methylimidazole-4-carboxamide;2-[(1S,3R)-3-[[5-fluoro-2-(7H-pyrrolo[2,3-d]pyrimidin-5-yl)pyrimidin-4-yl]methyl]cyclohexyl]-1-(3-methyl-1,2-oxazol-5-yl)ethanone (PubChem CID 159165744) has the molecular formula C136H136F7N45O7 and a molecular weight of 2645.88 g/mol. Its IUPAC name is N-[(1R,3R)-3-[[5-cyano-3-fluoro-6-(7H-pyrrolo[2,3-d]pyrimidin-5-yl)-2-pyridinyl]amino]cyclohexyl]-1-methylimidazole-4-carboxamide;N-[(1S,3R)-3-[[3,5-difluoro-6-(7H-pyrrolo[2,3-d]pyrimidin-5-yl)-2-pyridinyl]amino]cyclohexyl]-1-methylimidazole-4-carboxamide;5-[5-fluoro-4-[[(1R,3S)-3-(2-pyridin-4-ylprop-2-enyl)cyclohexyl]methyl]pyrimidin-2-yl]-7H-pyrrolo[2,3-d]pyrimidine;N-[(1R,3R)-3-[[5-fluoro-2-(7H-pyrrolo[2,3-d]pyrimidin-5-yl)pyrimidin-4-yl]amino]cyclohexyl]-5-methyl-1,2-oxazole-3-carboxamide;N-[(1S,3R)-3-[[5-fluoro-2-(7H-pyrrolo[2,3-d]pyrimidin-5-yl)pyrimidin-4-yl]methyl]cyclohexyl]-1-methylimidazole-4-carboxamide;2-[(1S,3R)-3-[[5-fluoro-2-(7H-pyrrolo[2,3-d]pyrimidin-5-yl)pyrimidin-4-yl]methyl]cyclohexyl]-1-(3-methyl-1,2-oxazol-5-yl)ethanone.

Molecular Properties

• Compound Name: N-[(1R,3R)-3-[[5-cyano-3-fluoro-6-(7H-pyrrolo[2,3-d]pyrimidin-5-yl)-2-pyridinyl]amino]cyclohexyl]-1-methylimidazole-4-carboxamide;N-[(1S,3R)-3-[[3,5-difluoro-6-(7H-pyrrolo[2,3-d]pyrimidin-5-yl)-2-pyridinyl]amino]cyclohexyl]-1-methylimidazole-4-carboxamide;5-[5-fluoro-4-[[(1R,3S)-3-(2-pyridin-4-ylprop-2-enyl)cyclohexyl]methyl]pyrimidin-2-yl]-7H-pyrrolo[2,3-d]pyrimidine;N-[(1R,3R)-3-[[5-fluoro-2-(7H-pyrrolo[2,3-d]pyrimidin-5-yl)pyrimidin-4-yl]amino]cyclohexyl]-5-methyl-1,2-oxazole-3-carboxamide;N-[(1S,3R)-3-[[5-fluoro-2-(7H-pyrrolo[2,3-d]pyrimidin-5-yl)pyrimidin-4-yl]methyl]cyclohexyl]-1-methylimidazole-4-carboxamide;2-[(1S,3R)-3-[[5-fluoro-2-(7H-pyrrolo[2,3-d]pyrimidin-5-yl)pyrimidin-4-yl]methyl]cyclohexyl]-1-(3-methyl-1,2-oxazol-5-yl)ethanone
• PubChem CID: 159165744
• Molecular Formula: C136H136F7N45O7
• Molecular Weight: 2645.88 g/mol
• Exact Mass: 2644.16
• IUPAC Name: N-[(1R,3R)-3-[[5-cyano-3-fluoro-6-(7H-pyrrolo[2,3-d]pyrimidin-5-yl)-2-pyridinyl]amino]cyclohexyl]-1-methylimidazole-4-carboxamide;N-[(1S,3R)-3-[[3,5-difluoro-6-(7H-pyrrolo[2,3-d]pyrimidin-5-yl)-2-pyridinyl]amino]cyclohexyl]-1-methylimidazole-4-carboxamide;5-[5-fluoro-4-[[(1R,3S)-3-(2-pyridin-4-ylprop-2-enyl)cyclohexyl]methyl]pyrimidin-2-yl]-7H-pyrrolo[2,3-d]pyrimidine;N-[(1R,3R)-3-[[5-fluoro-2-(7H-pyrrolo[2,3-d]pyrimidin-5-yl)pyrimidin-4-yl]amino]cyclohexyl]-5-methyl-1,2-oxazole-3-carboxamide;N-[(1S,3R)-3-[[5-fluoro-2-(7H-pyrrolo[2,3-d]pyrimidin-5-yl)pyrimidin-4-yl]methyl]cyclohexyl]-1-methylimidazole-4-carboxamide;2-[(1S,3R)-3-[[5-fluoro-2-(7H-pyrrolo[2,3-d]pyrimidin-5-yl)pyrimidin-4-yl]methyl]cyclohexyl]-1-(3-methyl-1,2-oxazol-5-yl)ethanone
• SMILES: C=C(C[C@H]1CCC[C@@H](Cc2nc(-c3c[nH]c4ncncc34)ncc2F)C1)c1ccncc1.Cc1cc(C(=O)C[C@H]2CCC[C@@H](Cc3nc(-c4c[nH]c5ncncc45)ncc3F)C2)on1.Cc1cc(C(=O)N[C@@H]2CCC[C@@H](Nc3nc(-c4c[nH]c5ncncc45)ncc3F)C2)no1.Cn1cnc(C(=O)N[C@@H]2CCC[C@@H](Nc3nc(-c4c[nH]c5ncncc45)c(C#N)cc3F)C2)c1.Cn1cnc(C(=O)N[C@H]2CCC[C@@H](Cc3nc(-c4c[nH]c5ncncc45)ncc3F)C2)c1.Cn1cnc(C(=O)N[C@H]2CCC[C@@H](Nc3nc(-c4c[nH]c5ncncc45)c(F)cc3F)C2)c1
• InChI: InChI=1S/C25H25FN6.C23H22FN9O.C23H23FN6O2.C22H22F2N8O.C22H23FN8O.C21H21FN8O2/c1-16(19-5-7-27-8-6-19)9-17-3-2-4-18(10-17)11-23-22(26)14-30-25(32-23)21-13-29-24-20(21)12-28-15-31-24;1-33-10-19(29-12-33)23(34)31-15-4-2-3-14(6-15)30-22-18(24)5-13(7-25)20(32-22)16-9-27-21-17(16)8-26-11-28-21;1-13-5-21(32-30-13)20(31)8-15-4-2-3-14(6-15)7-19-18(24)11-27-23(29-19)17-10-26-22-16(17)9-25-12-28-22;1-32-9-18(28-11-32)22(33)30-13-4-2-3-12(5-13)29-21-17(24)6-16(23)19(31-21)14-8-26-20-15(14)7-25-10-27-20;1-31-10-19(28-12-31)22(32)29-14-4-2-3-13(5-14)6-18-17(23)9-26-21(30-18)16-8-25-20-15(16)7-24-11-27-20;1-11-5-17(30-32-11)21(31)28-13-4-2-3-12(6-13)27-20-16(22)9-25-19(29-20)15-8-24-18-14(15)7-23-10-26-18/h5-8,12-15,17-18H,1-4,9-11H2,(H,28,29,31);5,8-12,14-15H,2-4,6H2,1H3,(H,30,32)(H,31,34)(H,26,27,28);5,9-12,14-15H,2-4,6-8H2,1H3,(H,25,26,28);6-13H,2-5H2,1H3,(H,29,31)(H,30,33)(H,25,26,27);7-14H,2-6H2,1H3,(H,29,32)(H,24,25,27);5,7-10,12-13H,2-4,6H2,1H3,(H,28,31)(H,23,24,26)(H,25,27,29)/t17-,18-;14-,15-;14-,15+;12-,13+;13-,14+;12-,13-/m111111/s1
• InChIKey: KLAXGAALTGYDOK-ZNTZYFQFSA-N
• XLogP: 21.80
• TPSA: 690.08 Ų
• H-Bond Donors: 13
• H-Bond Acceptors: 42
• Rotatable Bonds: 32
• Heavy Atoms: 195
• Complexity: —

Lipinski Rule of Five

4 violations

Rule	Value
MW ≤ 500	2645.88
LogP ≤ 5	21.80
H-Bond Donors ≤ 5	13
H-Bond Acceptors ≤ 10	42

Frequently Asked Questions

What is the IUPAC name of N-[(1R,3R)-3-[[5-cyano-3-fluoro-6-(7H-pyrrolo[2,3-d]pyrimidin-5-yl)-2-pyridinyl]amino]cyclohexyl]-1-methylimidazole-4-carboxamide;N-[(1S,3R)-3-[[3,5-difluoro-6-(7H-pyrrolo[2,3-d]pyrimidin-5-yl)-2-pyridinyl]amino]cyclohexyl]-1-methylimidazole-4-carboxamide;5-[5-fluoro-4-[[(1R,3S)-3-(2-pyridin-4-ylprop-2-enyl)cyclohexyl]methyl]pyrimidin-2-yl]-7H-pyrrolo[2,3-d]pyrimidine;N-[(1R,3R)-3-[[5-fluoro-2-(7H-pyrrolo[2,3-d]pyrimidin-5-yl)pyrimidin-4-yl]amino]cyclohexyl]-5-methyl-1,2-oxazole-3-carboxamide;N-[(1S,3R)-3-[[5-fluoro-2-(7H-pyrrolo[2,3-d]pyrimidin-5-yl)pyrimidin-4-yl]methyl]cyclohexyl]-1-methylimidazole-4-carboxamide;2-[(1S,3R)-3-[[5-fluoro-2-(7H-pyrrolo[2,3-d]pyrimidin-5-yl)pyrimidin-4-yl]methyl]cyclohexyl]-1-(3-methyl-1,2-oxazol-5-yl)ethanone?

The IUPAC name of N-[(1R,3R)-3-[[5-cyano-3-fluoro-6-(7H-pyrrolo[2,3-d]pyrimidin-5-yl)-2-pyridinyl]amino]cyclohexyl]-1-methylimidazole-4-carboxamide;N-[(1S,3R)-3-[[3,5-difluoro-6-(7H-pyrrolo[2,3-d]pyrimidin-5-yl)-2-pyridinyl]amino]cyclohexyl]-1-methylimidazole-4-carboxamide;5-[5-fluoro-4-[[(1R,3S)-3-(2-pyridin-4-ylprop-2-enyl)cyclohexyl]methyl]pyrimidin-2-yl]-7H-pyrrolo[2,3-d]pyrimidine;N-[(1R,3R)-3-[[5-fluoro-2-(7H-pyrrolo[2,3-d]pyrimidin-5-yl)pyrimidin-4-yl]amino]cyclohexyl]-5-methyl-1,2-oxazole-3-carboxamide;N-[(1S,3R)-3-[[5-fluoro-2-(7H-pyrrolo[2,3-d]pyrimidin-5-yl)pyrimidin-4-yl]methyl]cyclohexyl]-1-methylimidazole-4-carboxamide;2-[(1S,3R)-3-[[5-fluoro-2-(7H-pyrrolo[2,3-d]pyrimidin-5-yl)pyrimidin-4-yl]methyl]cyclohexyl]-1-(3-methyl-1,2-oxazol-5-yl)ethanone (CID 159165744) is N-[(1R,3R)-3-[[5-cyano-3-fluoro-6-(7H-pyrrolo[2,3-d]pyrimidin-5-yl)-2-pyridinyl]amino]cyclohexyl]-1-methylimidazole-4-carboxamide;N-[(1S,3R)-3-[[3,5-difluoro-6-(7H-pyrrolo[2,3-d]pyrimidin-5-yl)-2-pyridinyl]amino]cyclohexyl]-1-methylimidazole-4-carboxamide;5-[5-fluoro-4-[[(1R,3S)-3-(2-pyridin-4-ylprop-2-enyl)cyclohexyl]methyl]pyrimidin-2-yl]-7H-pyrrolo[2,3-d]pyrimidine;N-[(1R,3R)-3-[[5-fluoro-2-(7H-pyrrolo[2,3-d]pyrimidin-5-yl)pyrimidin-4-yl]amino]cyclohexyl]-5-methyl-1,2-oxazole-3-carboxamide;N-[(1S,3R)-3-[[5-fluoro-2-(7H-pyrrolo[2,3-d]pyrimidin-5-yl)pyrimidin-4-yl]methyl]cyclohexyl]-1-methylimidazole-4-carboxamide;2-[(1S,3R)-3-[[5-fluoro-2-(7H-pyrrolo[2,3-d]pyrimidin-5-yl)pyrimidin-4-yl]methyl]cyclohexyl]-1-(3-methyl-1,2-oxazol-5-yl)ethanone.

What is the SMILES notation for N-[(1R,3R)-3-[[5-cyano-3-fluoro-6-(7H-pyrrolo[2,3-d]pyrimidin-5-yl)-2-pyridinyl]amino]cyclohexyl]-1-methylimidazole-4-carboxamide;N-[(1S,3R)-3-[[3,5-difluoro-6-(7H-pyrrolo[2,3-d]pyrimidin-5-yl)-2-pyridinyl]amino]cyclohexyl]-1-methylimidazole-4-carboxamide;5-[5-fluoro-4-[[(1R,3S)-3-(2-pyridin-4-ylprop-2-enyl)cyclohexyl]methyl]pyrimidin-2-yl]-7H-pyrrolo[2,3-d]pyrimidine;N-[(1R,3R)-3-[[5-fluoro-2-(7H-pyrrolo[2,3-d]pyrimidin-5-yl)pyrimidin-4-yl]amino]cyclohexyl]-5-methyl-1,2-oxazole-3-carboxamide;N-[(1S,3R)-3-[[5-fluoro-2-(7H-pyrrolo[2,3-d]pyrimidin-5-yl)pyrimidin-4-yl]methyl]cyclohexyl]-1-methylimidazole-4-carboxamide;2-[(1S,3R)-3-[[5-fluoro-2-(7H-pyrrolo[2,3-d]pyrimidin-5-yl)pyrimidin-4-yl]methyl]cyclohexyl]-1-(3-methyl-1,2-oxazol-5-yl)ethanone?

The canonical SMILES for N-[(1R,3R)-3-[[5-cyano-3-fluoro-6-(7H-pyrrolo[2,3-d]pyrimidin-5-yl)-2-pyridinyl]amino]cyclohexyl]-1-methylimidazole-4-carboxamide;N-[(1S,3R)-3-[[3,5-difluoro-6-(7H-pyrrolo[2,3-d]pyrimidin-5-yl)-2-pyridinyl]amino]cyclohexyl]-1-methylimidazole-4-carboxamide;5-[5-fluoro-4-[[(1R,3S)-3-(2-pyridin-4-ylprop-2-enyl)cyclohexyl]methyl]pyrimidin-2-yl]-7H-pyrrolo[2,3-d]pyrimidine;N-[(1R,3R)-3-[[5-fluoro-2-(7H-pyrrolo[2,3-d]pyrimidin-5-yl)pyrimidin-4-yl]amino]cyclohexyl]-5-methyl-1,2-oxazole-3-carboxamide;N-[(1S,3R)-3-[[5-fluoro-2-(7H-pyrrolo[2,3-d]pyrimidin-5-yl)pyrimidin-4-yl]methyl]cyclohexyl]-1-methylimidazole-4-carboxamide;2-[(1S,3R)-3-[[5-fluoro-2-(7H-pyrrolo[2,3-d]pyrimidin-5-yl)pyrimidin-4-yl]methyl]cyclohexyl]-1-(3-methyl-1,2-oxazol-5-yl)ethanone is C=C(C[C@H]1CCC[C@@H](Cc2nc(-c3c[nH]c4ncncc34)ncc2F)C1)c1ccncc1.Cc1cc(C(=O)C[C@H]2CCC[C@@H](Cc3nc(-c4c[nH]c5ncncc45)ncc3F)C2)on1.Cc1cc(C(=O)N[C@@H]2CCC[C@@H](Nc3nc(-c4c[nH]c5ncncc45)ncc3F)C2)no1.Cn1cnc(C(=O)N[C@@H]2CCC[C@@H](Nc3nc(-c4c[nH]c5ncncc45)c(C#N)cc3F)C2)c1.Cn1cnc(C(=O)N[C@H]2CCC[C@@H](Cc3nc(-c4c[nH]c5ncncc45)ncc3F)C2)c1.Cn1cnc(C(=O)N[C@H]2CCC[C@@H](Nc3nc(-c4c[nH]c5ncncc45)c(F)cc3F)C2)c1.

What is the InChIKey of N-[(1R,3R)-3-[[5-cyano-3-fluoro-6-(7H-pyrrolo[2,3-d]pyrimidin-5-yl)-2-pyridinyl]amino]cyclohexyl]-1-methylimidazole-4-carboxamide;N-[(1S,3R)-3-[[3,5-difluoro-6-(7H-pyrrolo[2,3-d]pyrimidin-5-yl)-2-pyridinyl]amino]cyclohexyl]-1-methylimidazole-4-carboxamide;5-[5-fluoro-4-[[(1R,3S)-3-(2-pyridin-4-ylprop-2-enyl)cyclohexyl]methyl]pyrimidin-2-yl]-7H-pyrrolo[2,3-d]pyrimidine;N-[(1R,3R)-3-[[5-fluoro-2-(7H-pyrrolo[2,3-d]pyrimidin-5-yl)pyrimidin-4-yl]amino]cyclohexyl]-5-methyl-1,2-oxazole-3-carboxamide;N-[(1S,3R)-3-[[5-fluoro-2-(7H-pyrrolo[2,3-d]pyrimidin-5-yl)pyrimidin-4-yl]methyl]cyclohexyl]-1-methylimidazole-4-carboxamide;2-[(1S,3R)-3-[[5-fluoro-2-(7H-pyrrolo[2,3-d]pyrimidin-5-yl)pyrimidin-4-yl]methyl]cyclohexyl]-1-(3-methyl-1,2-oxazol-5-yl)ethanone?

The InChIKey is KLAXGAALTGYDOK-ZNTZYFQFSA-N. The full InChI is InChI=1S/C25H25FN6.C23H22FN9O.C23H23FN6O2.C22H22F2N8O.C22H23FN8O.C21H21FN8O2/c1-16(19-5-7-27-8-6-19)9-17-3-2-4-18(10-17)11-23-22(26)14-30-25(32-23)21-13-29-24-20(21)12-28-15-31-24;1-33-10-19(29-12-33)23(34)31-15-4-2-3-14(6-15)30-22-18(24)5-13(7-25)20(32-22)16-9-27-21-17(16)8-26-11-28-21;1-13-5-21(32-30-13)20(31)8-15-4-2-3-14(6-15)7-19-18(24)11-27-23(29-19)17-10-26-22-16(17)9-25-12-28-22;1-32-9-18(28-11-32)22(33)30-13-4-2-3-12(5-13)29-21-17(24)6-16(23)19(31-21)14-8-26-20-15(14)7-25-10-27-20;1-31-10-19(28-12-31)22(32)29-14-4-2-3-13(5-14)6-18-17(23)9-26-21(30-18)16-8-25-20-15(16)7-24-11-27-20;1-11-5-17(30-32-11)21(31)28-13-4-2-3-12(6-13)27-20-16(22)9-25-19(29-20)15-8-24-18-14(15)7-23-10-26-18/h5-8,12-15,17-18H,1-4,9-11H2,(H,28,29,31);5,8-12,14-15H,2-4,6H2,1H3,(H,30,32)(H,31,34)(H,26,27,28);5,9-12,14-15H,2-4,6-8H2,1H3,(H,25,26,28);6-13H,2-5H2,1H3,(H,29,31)(H,30,33)(H,25,26,27);7-14H,2-6H2,1H3,(H,29,32)(H,24,25,27);5,7-10,12-13H,2-4,6H2,1H3,(H,28,31)(H,23,24,26)(H,25,27,29)/t17-,18-;14-,15-;14-,15+;12-,13+;13-,14+;12-,13-/m111111/s1.

What are the key properties of N-[(1R,3R)-3-[[5-cyano-3-fluoro-6-(7H-pyrrolo[2,3-d]pyrimidin-5-yl)-2-pyridinyl]amino]cyclohexyl]-1-methylimidazole-4-carboxamide;N-[(1S,3R)-3-[[3,5-difluoro-6-(7H-pyrrolo[2,3-d]pyrimidin-5-yl)-2-pyridinyl]amino]cyclohexyl]-1-methylimidazole-4-carboxamide;5-[5-fluoro-4-[[(1R,3S)-3-(2-pyridin-4-ylprop-2-enyl)cyclohexyl]methyl]pyrimidin-2-yl]-7H-pyrrolo[2,3-d]pyrimidine;N-[(1R,3R)-3-[[5-fluoro-2-(7H-pyrrolo[2,3-d]pyrimidin-5-yl)pyrimidin-4-yl]amino]cyclohexyl]-5-methyl-1,2-oxazole-3-carboxamide;N-[(1S,3R)-3-[[5-fluoro-2-(7H-pyrrolo[2,3-d]pyrimidin-5-yl)pyrimidin-4-yl]methyl]cyclohexyl]-1-methylimidazole-4-carboxamide;2-[(1S,3R)-3-[[5-fluoro-2-(7H-pyrrolo[2,3-d]pyrimidin-5-yl)pyrimidin-4-yl]methyl]cyclohexyl]-1-(3-methyl-1,2-oxazol-5-yl)ethanone?

N-[(1R,3R)-3-[[5-cyano-3-fluoro-6-(7H-pyrrolo[2,3-d]pyrimidin-5-yl)-2-pyridinyl]amino]cyclohexyl]-1-methylimidazole-4-carboxamide;N-[(1S,3R)-3-[[3,5-difluoro-6-(7H-pyrrolo[2,3-d]pyrimidin-5-yl)-2-pyridinyl]amino]cyclohexyl]-1-methylimidazole-4-carboxamide;5-[5-fluoro-4-[[(1R,3S)-3-(2-pyridin-4-ylprop-2-enyl)cyclohexyl]methyl]pyrimidin-2-yl]-7H-pyrrolo[2,3-d]pyrimidine;N-[(1R,3R)-3-[[5-fluoro-2-(7H-pyrrolo[2,3-d]pyrimidin-5-yl)pyrimidin-4-yl]amino]cyclohexyl]-5-methyl-1,2-oxazole-3-carboxamide;N-[(1S,3R)-3-[[5-fluoro-2-(7H-pyrrolo[2,3-d]pyrimidin-5-yl)pyrimidin-4-yl]methyl]cyclohexyl]-1-methylimidazole-4-carboxamide;2-[(1S,3R)-3-[[5-fluoro-2-(7H-pyrrolo[2,3-d]pyrimidin-5-yl)pyrimidin-4-yl]methyl]cyclohexyl]-1-(3-methyl-1,2-oxazol-5-yl)ethanone has a molecular weight of 2645.88 g/mol, XLogP of 21.80, 32 rotatable bonds, 13 hydrogen bond donors, and 42 hydrogen bond acceptors.

Where does this data come from?

All data for N-[(1R,3R)-3-[[5-cyano-3-fluoro-6-(7H-pyrrolo[2,3-d]pyrimidin-5-yl)-2-pyridinyl]amino]cyclohexyl]-1-methylimidazole-4-carboxamide;N-[(1S,3R)-3-[[3,5-difluoro-6-(7H-pyrrolo[2,3-d]pyrimidin-5-yl)-2-pyridinyl]amino]cyclohexyl]-1-methylimidazole-4-carboxamide;5-[5-fluoro-4-[[(1R,3S)-3-(2-pyridin-4-ylprop-2-enyl)cyclohexyl]methyl]pyrimidin-2-yl]-7H-pyrrolo[2,3-d]pyrimidine;N-[(1R,3R)-3-[[5-fluoro-2-(7H-pyrrolo[2,3-d]pyrimidin-5-yl)pyrimidin-4-yl]amino]cyclohexyl]-5-methyl-1,2-oxazole-3-carboxamide;N-[(1S,3R)-3-[[5-fluoro-2-(7H-pyrrolo[2,3-d]pyrimidin-5-yl)pyrimidin-4-yl]methyl]cyclohexyl]-1-methylimidazole-4-carboxamide;2-[(1S,3R)-3-[[5-fluoro-2-(7H-pyrrolo[2,3-d]pyrimidin-5-yl)pyrimidin-4-yl]methyl]cyclohexyl]-1-(3-methyl-1,2-oxazol-5-yl)ethanone is sourced from PubChem (CID 159165744), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).