2-(8-chloro-2-methylimidazo[1,2-a]pyridin-6-yl)-7-piperidin-4-ylpyrazino[1,2-a]pyrimidin-4-one;2-(2,8-dimethylimidazo[1,2-a]pyridin-6-yl)-7-piperidin-4-ylpyrazino[1,2-a]pyrimidin-4-one;7-(4-ethylpiperazin-1-yl)-2-(2-methylindazol-5-yl)pyrazino[1,2-a]pyrimidin-4-one;7-[4-(2-hydroxyethyl)piperazin-1-yl]-2-(2-methylindazol-5-yl)pyrazino[1,2-a]pyrimidin-4-one;2-(2-methylindazol-5-yl)-7-(4-methylpiperazin-1-yl)pyrazino[1,2-a]pyrimidin-4-one

C103H108ClN33O6 — CID 159175783

About 2-(8-chloro-2-methylimidazo[1,2-a]pyridin-6-yl)-7-piperidin-4-ylpyrazino[1,2-a]pyrimidin-4-one;2-(2,8-dimethylimidazo[1,2-a]pyridin-6-yl)-7-piperidin-4-ylpyrazino[1,2-a]pyrimidin-4-one;7-(4-ethylpiperazin-1-yl)-2-(2-methylindazol-5-yl)pyrazino[1,2-a]pyrimidin-4-one;7-[4-(2-hydroxyethyl)piperazin-1-yl]-2-(2-methylindazol-5-yl)pyrazino[1,2-a]pyrimidin-4-one;2-(2-methylindazol-5-yl)-7-(4-methylpiperazin-1-yl)pyrazino[1,2-a]pyrimidin-4-one

2-(8-chloro-2-methylimidazo[1,2-a]pyridin-6-yl)-7-piperidin-4-ylpyrazino[1,2-a]pyrimidin-4-one;2-(2,8-dimethylimidazo[1,2-a]pyridin-6-yl)-7-piperidin-4-ylpyrazino[1,2-a]pyrimidin-4-one;7-(4-ethylpiperazin-1-yl)-2-(2-methylindazol-5-yl)pyrazino[1,2-a]pyrimidin-4-one;7-[4-(2-hydroxyethyl)piperazin-1-yl]-2-(2-methylindazol-5-yl)pyrazino[1,2-a]pyrimidin-4-one;2-(2-methylindazol-5-yl)-7-(4-methylpiperazin-1-yl)pyrazino[1,2-a]pyrimidin-4-one (PubChem CID 159175783) has the molecular formula C103H108ClN33O6 and a molecular weight of 1939.67 g/mol. Its IUPAC name is 2-(8-chloro-2-methylimidazo[1,2-a]pyridin-6-yl)-7-piperidin-4-ylpyrazino[1,2-a]pyrimidin-4-one;2-(2,8-dimethylimidazo[1,2-a]pyridin-6-yl)-7-piperidin-4-ylpyrazino[1,2-a]pyrimidin-4-one;7-(4-ethylpiperazin-1-yl)-2-(2-methylindazol-5-yl)pyrazino[1,2-a]pyrimidin-4-one;7-[4-(2-hydroxyethyl)piperazin-1-yl]-2-(2-methylindazol-5-yl)pyrazino[1,2-a]pyrimidin-4-one;2-(2-methylindazol-5-yl)-7-(4-methylpiperazin-1-yl)pyrazino[1,2-a]pyrimidin-4-one.

Molecular Properties

• Compound Name: 2-(8-chloro-2-methylimidazo[1,2-a]pyridin-6-yl)-7-piperidin-4-ylpyrazino[1,2-a]pyrimidin-4-one;2-(2,8-dimethylimidazo[1,2-a]pyridin-6-yl)-7-piperidin-4-ylpyrazino[1,2-a]pyrimidin-4-one;7-(4-ethylpiperazin-1-yl)-2-(2-methylindazol-5-yl)pyrazino[1,2-a]pyrimidin-4-one;7-[4-(2-hydroxyethyl)piperazin-1-yl]-2-(2-methylindazol-5-yl)pyrazino[1,2-a]pyrimidin-4-one;2-(2-methylindazol-5-yl)-7-(4-methylpiperazin-1-yl)pyrazino[1,2-a]pyrimidin-4-one
• PubChem CID: 159175783
• Molecular Formula: C103H108ClN33O6
• Molecular Weight: 1939.67 g/mol
• Exact Mass: 1937.88
• IUPAC Name: 2-(8-chloro-2-methylimidazo[1,2-a]pyridin-6-yl)-7-piperidin-4-ylpyrazino[1,2-a]pyrimidin-4-one;2-(2,8-dimethylimidazo[1,2-a]pyridin-6-yl)-7-piperidin-4-ylpyrazino[1,2-a]pyrimidin-4-one;7-(4-ethylpiperazin-1-yl)-2-(2-methylindazol-5-yl)pyrazino[1,2-a]pyrimidin-4-one;7-[4-(2-hydroxyethyl)piperazin-1-yl]-2-(2-methylindazol-5-yl)pyrazino[1,2-a]pyrimidin-4-one;2-(2-methylindazol-5-yl)-7-(4-methylpiperazin-1-yl)pyrazino[1,2-a]pyrimidin-4-one
• SMILES: CCN1CCN(c2cn3c(=O)cc(-c4ccc5nn(C)cc5c4)nc3cn2)CC1.CN1CCN(c2cn3c(=O)cc(-c4ccc5nn(C)cc5c4)nc3cn2)CC1.Cc1cn2cc(-c3cc(=O)n4cc(C5CCNCC5)ncc4n3)cc(C)c2n1.Cc1cn2cc(-c3cc(=O)n4cc(C5CCNCC5)ncc4n3)cc(Cl)c2n1.Cn1cc2cc(-c3cc(=O)n4cc(N5CCN(CCO)CC5)ncc4n3)ccc2n1
• InChI: InChI=1S/C21H23N7O2.C21H23N7O.C21H22N6O.C20H19ClN6O.C20H21N7O/c1-25-13-16-10-15(2-3-17(16)24-25)18-11-21(30)28-14-20(22-12-19(28)23-18)27-6-4-26(5-7-27)8-9-29;1-3-26-6-8-27(9-7-26)20-14-28-19(12-22-20)23-18(11-21(28)29)15-4-5-17-16(10-15)13-25(2)24-17;1-13-7-16(11-26-10-14(2)24-21(13)26)17-8-20(28)27-12-18(23-9-19(27)25-17)15-3-5-22-6-4-15;1-12-9-26-10-14(6-15(21)20(26)24-12)16-7-19(28)27-11-17(23-8-18(27)25-16)13-2-4-22-5-3-13;1-24-5-7-26(8-6-24)19-13-27-18(11-21-19)22-17(10-20(27)28)14-3-4-16-15(9-14)12-25(2)23-16/h2-3,10-14,29H,4-9H2,1H3;4-5,10-14H,3,6-9H2,1-2H3;7-12,15,22H,3-6H2,1-2H3;6-11,13,22H,2-5H2,1H3;3-4,9-13H,5-8H2,1-2H3
• InChIKey: KMGIDKXWRQVRND-UHFFFAOYSA-N
• XLogP: 9.26
• TPSA: 388.09 Ų
• H-Bond Donors: 3
• H-Bond Acceptors: 39
• Rotatable Bonds: 13
• Heavy Atoms: 143
• Complexity: —

Lipinski Rule of Five

3 violations

Rule	Value
MW ≤ 500	1939.67
LogP ≤ 5	9.26
H-Bond Donors ≤ 5	3
H-Bond Acceptors ≤ 10	39

Frequently Asked Questions

What is the IUPAC name of 2-(8-chloro-2-methylimidazo[1,2-a]pyridin-6-yl)-7-piperidin-4-ylpyrazino[1,2-a]pyrimidin-4-one;2-(2,8-dimethylimidazo[1,2-a]pyridin-6-yl)-7-piperidin-4-ylpyrazino[1,2-a]pyrimidin-4-one;7-(4-ethylpiperazin-1-yl)-2-(2-methylindazol-5-yl)pyrazino[1,2-a]pyrimidin-4-one;7-[4-(2-hydroxyethyl)piperazin-1-yl]-2-(2-methylindazol-5-yl)pyrazino[1,2-a]pyrimidin-4-one;2-(2-methylindazol-5-yl)-7-(4-methylpiperazin-1-yl)pyrazino[1,2-a]pyrimidin-4-one?

The IUPAC name of 2-(8-chloro-2-methylimidazo[1,2-a]pyridin-6-yl)-7-piperidin-4-ylpyrazino[1,2-a]pyrimidin-4-one;2-(2,8-dimethylimidazo[1,2-a]pyridin-6-yl)-7-piperidin-4-ylpyrazino[1,2-a]pyrimidin-4-one;7-(4-ethylpiperazin-1-yl)-2-(2-methylindazol-5-yl)pyrazino[1,2-a]pyrimidin-4-one;7-[4-(2-hydroxyethyl)piperazin-1-yl]-2-(2-methylindazol-5-yl)pyrazino[1,2-a]pyrimidin-4-one;2-(2-methylindazol-5-yl)-7-(4-methylpiperazin-1-yl)pyrazino[1,2-a]pyrimidin-4-one (CID 159175783) is 2-(8-chloro-2-methylimidazo[1,2-a]pyridin-6-yl)-7-piperidin-4-ylpyrazino[1,2-a]pyrimidin-4-one;2-(2,8-dimethylimidazo[1,2-a]pyridin-6-yl)-7-piperidin-4-ylpyrazino[1,2-a]pyrimidin-4-one;7-(4-ethylpiperazin-1-yl)-2-(2-methylindazol-5-yl)pyrazino[1,2-a]pyrimidin-4-one;7-[4-(2-hydroxyethyl)piperazin-1-yl]-2-(2-methylindazol-5-yl)pyrazino[1,2-a]pyrimidin-4-one;2-(2-methylindazol-5-yl)-7-(4-methylpiperazin-1-yl)pyrazino[1,2-a]pyrimidin-4-one.

What is the SMILES notation for 2-(8-chloro-2-methylimidazo[1,2-a]pyridin-6-yl)-7-piperidin-4-ylpyrazino[1,2-a]pyrimidin-4-one;2-(2,8-dimethylimidazo[1,2-a]pyridin-6-yl)-7-piperidin-4-ylpyrazino[1,2-a]pyrimidin-4-one;7-(4-ethylpiperazin-1-yl)-2-(2-methylindazol-5-yl)pyrazino[1,2-a]pyrimidin-4-one;7-[4-(2-hydroxyethyl)piperazin-1-yl]-2-(2-methylindazol-5-yl)pyrazino[1,2-a]pyrimidin-4-one;2-(2-methylindazol-5-yl)-7-(4-methylpiperazin-1-yl)pyrazino[1,2-a]pyrimidin-4-one?

The canonical SMILES for 2-(8-chloro-2-methylimidazo[1,2-a]pyridin-6-yl)-7-piperidin-4-ylpyrazino[1,2-a]pyrimidin-4-one;2-(2,8-dimethylimidazo[1,2-a]pyridin-6-yl)-7-piperidin-4-ylpyrazino[1,2-a]pyrimidin-4-one;7-(4-ethylpiperazin-1-yl)-2-(2-methylindazol-5-yl)pyrazino[1,2-a]pyrimidin-4-one;7-[4-(2-hydroxyethyl)piperazin-1-yl]-2-(2-methylindazol-5-yl)pyrazino[1,2-a]pyrimidin-4-one;2-(2-methylindazol-5-yl)-7-(4-methylpiperazin-1-yl)pyrazino[1,2-a]pyrimidin-4-one is CCN1CCN(c2cn3c(=O)cc(-c4ccc5nn(C)cc5c4)nc3cn2)CC1.CN1CCN(c2cn3c(=O)cc(-c4ccc5nn(C)cc5c4)nc3cn2)CC1.Cc1cn2cc(-c3cc(=O)n4cc(C5CCNCC5)ncc4n3)cc(C)c2n1.Cc1cn2cc(-c3cc(=O)n4cc(C5CCNCC5)ncc4n3)cc(Cl)c2n1.Cn1cc2cc(-c3cc(=O)n4cc(N5CCN(CCO)CC5)ncc4n3)ccc2n1.

What is the InChIKey of 2-(8-chloro-2-methylimidazo[1,2-a]pyridin-6-yl)-7-piperidin-4-ylpyrazino[1,2-a]pyrimidin-4-one;2-(2,8-dimethylimidazo[1,2-a]pyridin-6-yl)-7-piperidin-4-ylpyrazino[1,2-a]pyrimidin-4-one;7-(4-ethylpiperazin-1-yl)-2-(2-methylindazol-5-yl)pyrazino[1,2-a]pyrimidin-4-one;7-[4-(2-hydroxyethyl)piperazin-1-yl]-2-(2-methylindazol-5-yl)pyrazino[1,2-a]pyrimidin-4-one;2-(2-methylindazol-5-yl)-7-(4-methylpiperazin-1-yl)pyrazino[1,2-a]pyrimidin-4-one?

The InChIKey is KMGIDKXWRQVRND-UHFFFAOYSA-N. The full InChI is InChI=1S/C21H23N7O2.C21H23N7O.C21H22N6O.C20H19ClN6O.C20H21N7O/c1-25-13-16-10-15(2-3-17(16)24-25)18-11-21(30)28-14-20(22-12-19(28)23-18)27-6-4-26(5-7-27)8-9-29;1-3-26-6-8-27(9-7-26)20-14-28-19(12-22-20)23-18(11-21(28)29)15-4-5-17-16(10-15)13-25(2)24-17;1-13-7-16(11-26-10-14(2)24-21(13)26)17-8-20(28)27-12-18(23-9-19(27)25-17)15-3-5-22-6-4-15;1-12-9-26-10-14(6-15(21)20(26)24-12)16-7-19(28)27-11-17(23-8-18(27)25-16)13-2-4-22-5-3-13;1-24-5-7-26(8-6-24)19-13-27-18(11-21-19)22-17(10-20(27)28)14-3-4-16-15(9-14)12-25(2)23-16/h2-3,10-14,29H,4-9H2,1H3;4-5,10-14H,3,6-9H2,1-2H3;7-12,15,22H,3-6H2,1-2H3;6-11,13,22H,2-5H2,1H3;3-4,9-13H,5-8H2,1-2H3.

What are the key properties of 2-(8-chloro-2-methylimidazo[1,2-a]pyridin-6-yl)-7-piperidin-4-ylpyrazino[1,2-a]pyrimidin-4-one;2-(2,8-dimethylimidazo[1,2-a]pyridin-6-yl)-7-piperidin-4-ylpyrazino[1,2-a]pyrimidin-4-one;7-(4-ethylpiperazin-1-yl)-2-(2-methylindazol-5-yl)pyrazino[1,2-a]pyrimidin-4-one;7-[4-(2-hydroxyethyl)piperazin-1-yl]-2-(2-methylindazol-5-yl)pyrazino[1,2-a]pyrimidin-4-one;2-(2-methylindazol-5-yl)-7-(4-methylpiperazin-1-yl)pyrazino[1,2-a]pyrimidin-4-one?

2-(8-chloro-2-methylimidazo[1,2-a]pyridin-6-yl)-7-piperidin-4-ylpyrazino[1,2-a]pyrimidin-4-one;2-(2,8-dimethylimidazo[1,2-a]pyridin-6-yl)-7-piperidin-4-ylpyrazino[1,2-a]pyrimidin-4-one;7-(4-ethylpiperazin-1-yl)-2-(2-methylindazol-5-yl)pyrazino[1,2-a]pyrimidin-4-one;7-[4-(2-hydroxyethyl)piperazin-1-yl]-2-(2-methylindazol-5-yl)pyrazino[1,2-a]pyrimidin-4-one;2-(2-methylindazol-5-yl)-7-(4-methylpiperazin-1-yl)pyrazino[1,2-a]pyrimidin-4-one has a molecular weight of 1939.67 g/mol, XLogP of 9.26, 13 rotatable bonds, 3 hydrogen bond donors, and 39 hydrogen bond acceptors.

Where does this data come from?

All data for 2-(8-chloro-2-methylimidazo[1,2-a]pyridin-6-yl)-7-piperidin-4-ylpyrazino[1,2-a]pyrimidin-4-one;2-(2,8-dimethylimidazo[1,2-a]pyridin-6-yl)-7-piperidin-4-ylpyrazino[1,2-a]pyrimidin-4-one;7-(4-ethylpiperazin-1-yl)-2-(2-methylindazol-5-yl)pyrazino[1,2-a]pyrimidin-4-one;7-[4-(2-hydroxyethyl)piperazin-1-yl]-2-(2-methylindazol-5-yl)pyrazino[1,2-a]pyrimidin-4-one;2-(2-methylindazol-5-yl)-7-(4-methylpiperazin-1-yl)pyrazino[1,2-a]pyrimidin-4-one is sourced from PubChem (CID 159175783), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).