1-(cyclobutylmethyl)-8-(dimethylamino)-3-[3-(6-fluoro-3-pyridinyl)-2-oxopropyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;1-(cyclobutylmethyl)-8-(dimethylamino)-3-[(2-methoxy-4-pyridinyl)methyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;1-(cyclobutylmethyl)-8-(dimethylamino)-3-[3-(2-methylpyrimidin-5-yl)-2-oxopropyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;1-[1-(cyclobutylmethyl)-8-(dimethylamino)-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-3-(5-methoxypyrimidin-2-yl)propan-2-one;8-(dimethylamino)-1-[(1-hydroxycyclobutyl)methyl]-3-(2-oxobutyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;2-[8-(dimethylamino)-1-[(1-hydroxycyclobutyl)methyl]-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]acetamide;5-[8-(dimethylamino)-1-(2-methylpropyl)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-4-oxopentanamide;2-[8-(dimethylamino)-2-oxo-3-(2-oxobutyl)-8-phenyl-1,3-diazaspiro[4.5]decan-1-yl]-N,N-dimethylacetamide;2-[8-(dimethylamino)-2-oxo-3-(2-oxo-3-pyrimidin-4-ylpropyl)-8-phenyl-1,3-diazaspiro[4.5]decan-1-yl]-N,N-dimethylacetamide;methyl 2-[3-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-2-oxopropyl]pyridine-4-carboxylate

C270H376FN43O27 — CID 159182824

IUPAC1-(cyclobutylmethyl)-8-(dimethylamino)-3-[3-(6-fluoro-3-pyridinyl)-2-oxopropyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;1-(cyclobutylmethyl)-8-(dimethylamino)-3-[(2-methoxy-4-pyridinyl)methyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;1-(cyclobutylmethyl)-8-(dimethylamino)-3-[3-(2-methylpyrimidin-5-yl)-2-oxopropyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;1-[1-(cyclobutylmethyl)-8-(dimethylamino)-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-3-(5-methoxypyrimidin-2-yl)propan-2-one;8-(dimethylamino)-1-[(1-hydroxycyclobutyl)methyl]-3-(2-oxobutyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;2-[8-(dimethylamino)-1-[(1-hydroxycyclobutyl)methyl]-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]acetamide;5-[8-(dimethylamino)-1-(2-methylpropyl)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-4-oxopentanamide;2-[8-(dimethylamino)-2-oxo-3-(2-oxobutyl)-8-phenyl-1,3-diazaspiro[4.5]decan-1-yl]-N,N-dimethylacetamide;2-[8-(dimethylamino)-2-oxo-3-(2-oxo-3-pyrimidin-4-ylpropyl)-8-phenyl-1,3-diazaspiro[4.5]decan-1-yl]-N,N-dimethylacetamide;methyl 2-[3-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-2-oxopropyl]pyridine-4-carboxylate
SMILESCC(C)CN1C(=O)N(CC(=O)CCC(N)=O)CC12CCC(c1ccccc1)(N(C)C)CC2.CCC(=O)CN1CC2(CCC(c3ccccc3)(N(C)C)CC2)N(CC(=O)N(C)C)C1=O.CCC(=O)CN1CC2(CCC(c3ccccc3)(N(C)C)CC2)N(CC2(O)CCC2)C1=O.CN(C)C(=O)CN1C(=O)N(CC(=O)Cc2ccncn2)CC12CCC(c1ccccc1)(N(C)C)CC2.CN(C)C1(c2ccccc2)CCC2(CC1)CN(CC(=O)Cc1ccc(F)nc1)C(=O)N2CC1CCC1.CN(C)C1(c2ccccc2)CCC2(CC1)CN(CC(N)=O)C(=O)N2CC1(O)CCC1.COC(=O)c1ccnc(CC(=O)CN2CC3(CCC(c4ccccc4)(N(C)C)CC3)N(CC3CCC3)C2=O)c1.COc1cc(CN2CC3(CCC(c4ccccc4)(N(C)C)CC3)N(CC3CCC3)C2=O)ccn1.COc1cnc(CC(=O)CN2CN(CC3CCC3)C3(CCC(c4ccccc4)(N(C)C)CC3)C2)nc1.Cc1ncc(CC(=O)CN2CC3(CCC(c4ccccc4)(N(C)C)CC3)N(CC3CCC3)C2=O)cn1
InChIInChI=1S/C31H40N4O4.C29H37FN4O2.C29H41N5O2.C29H39N5O2.C28H38N4O2.C27H36N6O3.C25H38N4O3.C25H37N3O3.C24H36N4O3.C23H34N4O3/c1-33(2)31(25-10-5-4-6-11-25)15-13-30(14-16-31)22-34(29(38)35(30)20-23-8-7-9-23)21-27(36)19-26-18-24(12-17-32-26)28(37)39-3;1-32(2)29(24-9-4-3-5-10-24)15-13-28(14-16-29)21-33(27(36)34(28)19-22-7-6-8-22)20-25(35)17-23-11-12-26(30)31-18-23;1-32(2)29(24-10-5-4-6-11-24)14-12-28(13-15-29)21-33(22-34(28)19-23-8-7-9-23)20-25(35)16-27-30-17-26(36-3)18-31-27;1-22-30-17-24(18-31-22)16-26(35)20-33-21-28(34(27(33)36)19-23-8-7-9-23)12-14-29(15-13-28,32(2)3)25-10-5-4-6-11-25;1-30(2)28(24-10-5-4-6-11-24)15-13-27(14-16-28)21-31(19-23-12-17-29-25(18-23)34-3)26(33)32(27)20-22-8-7-9-22;1-30(2)24(35)18-33-25(36)32(17-23(34)16-22-10-15-28-20-29-22)19-26(33)11-13-27(14-12-26,31(3)4)21-8-6-5-7-9-21;1-19(2)16-29-23(32)28(17-21(30)10-11-22(26)31)18-24(29)12-14-25(15-13-24,27(3)4)20-8-6-5-7-9-20;1-4-21(29)17-27-18-23(28(22(27)30)19-24(31)11-8-12-24)13-15-25(16-14-23,26(2)3)20-9-6-5-7-10-20;1-6-20(29)16-27-18-23(28(22(27)31)17-21(30)25(2)3)12-14-24(15-13-23,26(4)5)19-10-8-7-9-11-19;1-25(2)23(18-7-4-3-5-8-18)13-11-21(12-14-23)16-26(15-19(24)28)20(29)27(21)17-22(30)9-6-10-22/h4-6,10-12,17-18,23H,7-9,13-16,19-22H2,1-3H3;3-5,9-12,18,22H,6-8,13-17,19-21H2,1-2H3;4-6,10-11,17-18,23H,7-9,12-16,19-22H2,1-3H3;4-6,10-11,17-18,23H,7-9,12-16,19-21H2,1-3H3;4-6,10-12,17-18,22H,7-9,13-16,19-21H2,1-3H3;5-10,15,20H,11-14,16-19H2,1-4H3;5-9,19H,10-18H2,1-4H3,(H2,26,31);5-7,9-10,31H,4,8,11-19H2,1-3H3;7-11H,6,12-18H2,1-5H3;3-5,7-8,30H,6,9-17H2,1-2H3,(H2,24,28)
InChIKeyKNCPOCUDQXMRDL-UHFFFAOYSA-N
MW4675.25 g/mol
LogP34.78
Rot. Bonds78

About 1-(cyclobutylmethyl)-8-(dimethylamino)-3-[3-(6-fluoro-3-pyridinyl)-2-oxopropyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;1-(cyclobutylmethyl)-8-(dimethylamino)-3-[(2-methoxy-4-pyridinyl)methyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;1-(cyclobutylmethyl)-8-(dimethylamino)-3-[3-(2-methylpyrimidin-5-yl)-2-oxopropyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;1-[1-(cyclobutylmethyl)-8-(dimethylamino)-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-3-(5-methoxypyrimidin-2-yl)propan-2-one;8-(dimethylamino)-1-[(1-hydroxycyclobutyl)methyl]-3-(2-oxobutyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;2-[8-(dimethylamino)-1-[(1-hydroxycyclobutyl)methyl]-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]acetamide;5-[8-(dimethylamino)-1-(2-methylpropyl)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-4-oxopentanamide;2-[8-(dimethylamino)-2-oxo-3-(2-oxobutyl)-8-phenyl-1,3-diazaspiro[4.5]decan-1-yl]-N,N-dimethylacetamide;2-[8-(dimethylamino)-2-oxo-3-(2-oxo-3-pyrimidin-4-ylpropyl)-8-phenyl-1,3-diazaspiro[4.5]decan-1-yl]-N,N-dimethylacetamide;methyl 2-[3-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-2-oxopropyl]pyridine-4-carboxylate

1-(cyclobutylmethyl)-8-(dimethylamino)-3-[3-(6-fluoro-3-pyridinyl)-2-oxopropyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;1-(cyclobutylmethyl)-8-(dimethylamino)-3-[(2-methoxy-4-pyridinyl)methyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;1-(cyclobutylmethyl)-8-(dimethylamino)-3-[3-(2-methylpyrimidin-5-yl)-2-oxopropyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;1-[1-(cyclobutylmethyl)-8-(dimethylamino)-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-3-(5-methoxypyrimidin-2-yl)propan-2-one;8-(dimethylamino)-1-[(1-hydroxycyclobutyl)methyl]-3-(2-oxobutyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;2-[8-(dimethylamino)-1-[(1-hydroxycyclobutyl)methyl]-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]acetamide;5-[8-(dimethylamino)-1-(2-methylpropyl)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-4-oxopentanamide;2-[8-(dimethylamino)-2-oxo-3-(2-oxobutyl)-8-phenyl-1,3-diazaspiro[4.5]decan-1-yl]-N,N-dimethylacetamide;2-[8-(dimethylamino)-2-oxo-3-(2-oxo-3-pyrimidin-4-ylpropyl)-8-phenyl-1,3-diazaspiro[4.5]decan-1-yl]-N,N-dimethylacetamide;methyl 2-[3-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-2-oxopropyl]pyridine-4-carboxylate (PubChem CID 159182824) has the molecular formula C270H376FN43O27 and a molecular weight of 4675.25 g/mol. Its IUPAC name is 1-(cyclobutylmethyl)-8-(dimethylamino)-3-[3-(6-fluoro-3-pyridinyl)-2-oxopropyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;1-(cyclobutylmethyl)-8-(dimethylamino)-3-[(2-methoxy-4-pyridinyl)methyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;1-(cyclobutylmethyl)-8-(dimethylamino)-3-[3-(2-methylpyrimidin-5-yl)-2-oxopropyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;1-[1-(cyclobutylmethyl)-8-(dimethylamino)-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-3-(5-methoxypyrimidin-2-yl)propan-2-one;8-(dimethylamino)-1-[(1-hydroxycyclobutyl)methyl]-3-(2-oxobutyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;2-[8-(dimethylamino)-1-[(1-hydroxycyclobutyl)methyl]-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]acetamide;5-[8-(dimethylamino)-1-(2-methylpropyl)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-4-oxopentanamide;2-[8-(dimethylamino)-2-oxo-3-(2-oxobutyl)-8-phenyl-1,3-diazaspiro[4.5]decan-1-yl]-N,N-dimethylacetamide;2-[8-(dimethylamino)-2-oxo-3-(2-oxo-3-pyrimidin-4-ylpropyl)-8-phenyl-1,3-diazaspiro[4.5]decan-1-yl]-N,N-dimethylacetamide;methyl 2-[3-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-2-oxopropyl]pyridine-4-carboxylate.

Molecular Properties

Compound Name1-(cyclobutylmethyl)-8-(dimethylamino)-3-[3-(6-fluoro-3-pyridinyl)-2-oxopropyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;1-(cyclobutylmethyl)-8-(dimethylamino)-3-[(2-methoxy-4-pyridinyl)methyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;1-(cyclobutylmethyl)-8-(dimethylamino)-3-[3-(2-methylpyrimidin-5-yl)-2-oxopropyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;1-[1-(cyclobutylmethyl)-8-(dimethylamino)-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-3-(5-methoxypyrimidin-2-yl)propan-2-one;8-(dimethylamino)-1-[(1-hydroxycyclobutyl)methyl]-3-(2-oxobutyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;2-[8-(dimethylamino)-1-[(1-hydroxycyclobutyl)methyl]-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]acetamide;5-[8-(dimethylamino)-1-(2-methylpropyl)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-4-oxopentanamide;2-[8-(dimethylamino)-2-oxo-3-(2-oxobutyl)-8-phenyl-1,3-diazaspiro[4.5]decan-1-yl]-N,N-dimethylacetamide;2-[8-(dimethylamino)-2-oxo-3-(2-oxo-3-pyrimidin-4-ylpropyl)-8-phenyl-1,3-diazaspiro[4.5]decan-1-yl]-N,N-dimethylacetamide;methyl 2-[3-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-2-oxopropyl]pyridine-4-carboxylate
PubChem CID159182824
Molecular FormulaC270H376FN43O27
Molecular Weight4675.25 g/mol
Exact Mass4671.94
IUPAC Name1-(cyclobutylmethyl)-8-(dimethylamino)-3-[3-(6-fluoro-3-pyridinyl)-2-oxopropyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;1-(cyclobutylmethyl)-8-(dimethylamino)-3-[(2-methoxy-4-pyridinyl)methyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;1-(cyclobutylmethyl)-8-(dimethylamino)-3-[3-(2-methylpyrimidin-5-yl)-2-oxopropyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;1-[1-(cyclobutylmethyl)-8-(dimethylamino)-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-3-(5-methoxypyrimidin-2-yl)propan-2-one;8-(dimethylamino)-1-[(1-hydroxycyclobutyl)methyl]-3-(2-oxobutyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;2-[8-(dimethylamino)-1-[(1-hydroxycyclobutyl)methyl]-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]acetamide;5-[8-(dimethylamino)-1-(2-methylpropyl)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-4-oxopentanamide;2-[8-(dimethylamino)-2-oxo-3-(2-oxobutyl)-8-phenyl-1,3-diazaspiro[4.5]decan-1-yl]-N,N-dimethylacetamide;2-[8-(dimethylamino)-2-oxo-3-(2-oxo-3-pyrimidin-4-ylpropyl)-8-phenyl-1,3-diazaspiro[4.5]decan-1-yl]-N,N-dimethylacetamide;methyl 2-[3-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-2-oxopropyl]pyridine-4-carboxylate
SMILESCC(C)CN1C(=O)N(CC(=O)CCC(N)=O)CC12CCC(c1ccccc1)(N(C)C)CC2.CCC(=O)CN1CC2(CCC(c3ccccc3)(N(C)C)CC2)N(CC(=O)N(C)C)C1=O.CCC(=O)CN1CC2(CCC(c3ccccc3)(N(C)C)CC2)N(CC2(O)CCC2)C1=O.CN(C)C(=O)CN1C(=O)N(CC(=O)Cc2ccncn2)CC12CCC(c1ccccc1)(N(C)C)CC2.CN(C)C1(c2ccccc2)CCC2(CC1)CN(CC(=O)Cc1ccc(F)nc1)C(=O)N2CC1CCC1.CN(C)C1(c2ccccc2)CCC2(CC1)CN(CC(N)=O)C(=O)N2CC1(O)CCC1.COC(=O)c1ccnc(CC(=O)CN2CC3(CCC(c4ccccc4)(N(C)C)CC3)N(CC3CCC3)C2=O)c1.COc1cc(CN2CC3(CCC(c4ccccc4)(N(C)C)CC3)N(CC3CCC3)C2=O)ccn1.COc1cnc(CC(=O)CN2CN(CC3CCC3)C3(CCC(c4ccccc4)(N(C)C)CC3)C2)nc1.Cc1ncc(CC(=O)CN2CC3(CCC(c4ccccc4)(N(C)C)CC3)N(CC3CCC3)C2=O)cn1
InChIInChI=1S/C31H40N4O4.C29H37FN4O2.C29H41N5O2.C29H39N5O2.C28H38N4O2.C27H36N6O3.C25H38N4O3.C25H37N3O3.C24H36N4O3.C23H34N4O3/c1-33(2)31(25-10-5-4-6-11-25)15-13-30(14-16-31)22-34(29(38)35(30)20-23-8-7-9-23)21-27(36)19-26-18-24(12-17-32-26)28(37)39-3;1-32(2)29(24-9-4-3-5-10-24)15-13-28(14-16-29)21-33(27(36)34(28)19-22-7-6-8-22)20-25(35)17-23-11-12-26(30)31-18-23;1-32(2)29(24-10-5-4-6-11-24)14-12-28(13-15-29)21-33(22-34(28)19-23-8-7-9-23)20-25(35)16-27-30-17-26(36-3)18-31-27;1-22-30-17-24(18-31-22)16-26(35)20-33-21-28(34(27(33)36)19-23-8-7-9-23)12-14-29(15-13-28,32(2)3)25-10-5-4-6-11-25;1-30(2)28(24-10-5-4-6-11-24)15-13-27(14-16-28)21-31(19-23-12-17-29-25(18-23)34-3)26(33)32(27)20-22-8-7-9-22;1-30(2)24(35)18-33-25(36)32(17-23(34)16-22-10-15-28-20-29-22)19-26(33)11-13-27(14-12-26,31(3)4)21-8-6-5-7-9-21;1-19(2)16-29-23(32)28(17-21(30)10-11-22(26)31)18-24(29)12-14-25(15-13-24,27(3)4)20-8-6-5-7-9-20;1-4-21(29)17-27-18-23(28(22(27)30)19-24(31)11-8-12-24)13-15-25(16-14-23,26(2)3)20-9-6-5-7-10-20;1-6-20(29)16-27-18-23(28(22(27)31)17-21(30)25(2)3)12-14-24(15-13-23,26(4)5)19-10-8-7-9-11-19;1-25(2)23(18-7-4-3-5-8-18)13-11-21(12-14-23)16-26(15-19(24)28)20(29)27(21)17-22(30)9-6-10-22/h4-6,10-12,17-18,23H,7-9,13-16,19-22H2,1-3H3;3-5,9-12,18,22H,6-8,13-17,19-21H2,1-2H3;4-6,10-11,17-18,23H,7-9,12-16,19-22H2,1-3H3;4-6,10-11,17-18,23H,7-9,12-16,19-21H2,1-3H3;4-6,10-12,17-18,22H,7-9,13-16,19-21H2,1-3H3;5-10,15,20H,11-14,16-19H2,1-4H3;5-9,19H,10-18H2,1-4H3,(H2,26,31);5-7,9-10,31H,4,8,11-19H2,1-3H3;7-11H,6,12-18H2,1-5H3;3-5,7-8,30H,6,9-17H2,1-2H3,(H2,24,28)
InChIKeyKNCPOCUDQXMRDL-UHFFFAOYSA-N
XLogP34.78
TPSA715.42 Ų
H-Bond Donors4
H-Bond Acceptors48
Rotatable Bonds78
Heavy Atoms341
Complexity—

Lipinski Rule of Five

3 violations

RuleValue
MW ≤ 5004675.25
LogP ≤ 534.78
H-Bond Donors ≤ 54
H-Bond Acceptors ≤ 1048

Analyze 1-(cyclobutylmethyl)-8-(dimethylamino)-3-[3-(6-fluoro-3-pyridinyl)-2-oxopropyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;1-(cyclobutylmethyl)-8-(dimethylamino)-3-[(2-methoxy-4-pyridinyl)methyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;1-(cyclobutylmethyl)-8-(dimethylamino)-3-[3-(2-methylpyrimidin-5-yl)-2-oxopropyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;1-[1-(cyclobutylmethyl)-8-(dimethylamino)-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-3-(5-methoxypyrimidin-2-yl)propan-2-one;8-(dimethylamino)-1-[(1-hydroxycyclobutyl)methyl]-3-(2-oxobutyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;2-[8-(dimethylamino)-1-[(1-hydroxycyclobutyl)methyl]-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]acetamide;5-[8-(dimethylamino)-1-(2-methylpropyl)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-4-oxopentanamide;2-[8-(dimethylamino)-2-oxo-3-(2-oxobutyl)-8-phenyl-1,3-diazaspiro[4.5]decan-1-yl]-N,N-dimethylacetamide;2-[8-(dimethylamino)-2-oxo-3-(2-oxo-3-pyrimidin-4-ylpropyl)-8-phenyl-1,3-diazaspiro[4.5]decan-1-yl]-N,N-dimethylacetamide;methyl 2-[3-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-2-oxopropyl]pyridine-4-carboxylate with MolForge

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What is the IUPAC name of 1-(cyclobutylmethyl)-8-(dimethylamino)-3-[3-(6-fluoro-3-pyridinyl)-2-oxopropyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;1-(cyclobutylmethyl)-8-(dimethylamino)-3-[(2-methoxy-4-pyridinyl)methyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;1-(cyclobutylmethyl)-8-(dimethylamino)-3-[3-(2-methylpyrimidin-5-yl)-2-oxopropyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;1-[1-(cyclobutylmethyl)-8-(dimethylamino)-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-3-(5-methoxypyrimidin-2-yl)propan-2-one;8-(dimethylamino)-1-[(1-hydroxycyclobutyl)methyl]-3-(2-oxobutyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;2-[8-(dimethylamino)-1-[(1-hydroxycyclobutyl)methyl]-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]acetamide;5-[8-(dimethylamino)-1-(2-methylpropyl)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-4-oxopentanamide;2-[8-(dimethylamino)-2-oxo-3-(2-oxobutyl)-8-phenyl-1,3-diazaspiro[4.5]decan-1-yl]-N,N-dimethylacetamide;2-[8-(dimethylamino)-2-oxo-3-(2-oxo-3-pyrimidin-4-ylpropyl)-8-phenyl-1,3-diazaspiro[4.5]decan-1-yl]-N,N-dimethylacetamide;methyl 2-[3-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-2-oxopropyl]pyridine-4-carboxylate?
The IUPAC name of 1-(cyclobutylmethyl)-8-(dimethylamino)-3-[3-(6-fluoro-3-pyridinyl)-2-oxopropyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;1-(cyclobutylmethyl)-8-(dimethylamino)-3-[(2-methoxy-4-pyridinyl)methyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;1-(cyclobutylmethyl)-8-(dimethylamino)-3-[3-(2-methylpyrimidin-5-yl)-2-oxopropyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;1-[1-(cyclobutylmethyl)-8-(dimethylamino)-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-3-(5-methoxypyrimidin-2-yl)propan-2-one;8-(dimethylamino)-1-[(1-hydroxycyclobutyl)methyl]-3-(2-oxobutyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;2-[8-(dimethylamino)-1-[(1-hydroxycyclobutyl)methyl]-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]acetamide;5-[8-(dimethylamino)-1-(2-methylpropyl)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-4-oxopentanamide;2-[8-(dimethylamino)-2-oxo-3-(2-oxobutyl)-8-phenyl-1,3-diazaspiro[4.5]decan-1-yl]-N,N-dimethylacetamide;2-[8-(dimethylamino)-2-oxo-3-(2-oxo-3-pyrimidin-4-ylpropyl)-8-phenyl-1,3-diazaspiro[4.5]decan-1-yl]-N,N-dimethylacetamide;methyl 2-[3-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-2-oxopropyl]pyridine-4-carboxylate (CID 159182824) is 1-(cyclobutylmethyl)-8-(dimethylamino)-3-[3-(6-fluoro-3-pyridinyl)-2-oxopropyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;1-(cyclobutylmethyl)-8-(dimethylamino)-3-[(2-methoxy-4-pyridinyl)methyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;1-(cyclobutylmethyl)-8-(dimethylamino)-3-[3-(2-methylpyrimidin-5-yl)-2-oxopropyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;1-[1-(cyclobutylmethyl)-8-(dimethylamino)-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-3-(5-methoxypyrimidin-2-yl)propan-2-one;8-(dimethylamino)-1-[(1-hydroxycyclobutyl)methyl]-3-(2-oxobutyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;2-[8-(dimethylamino)-1-[(1-hydroxycyclobutyl)methyl]-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]acetamide;5-[8-(dimethylamino)-1-(2-methylpropyl)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-4-oxopentanamide;2-[8-(dimethylamino)-2-oxo-3-(2-oxobutyl)-8-phenyl-1,3-diazaspiro[4.5]decan-1-yl]-N,N-dimethylacetamide;2-[8-(dimethylamino)-2-oxo-3-(2-oxo-3-pyrimidin-4-ylpropyl)-8-phenyl-1,3-diazaspiro[4.5]decan-1-yl]-N,N-dimethylacetamide;methyl 2-[3-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-2-oxopropyl]pyridine-4-carboxylate.
What is the SMILES notation for 1-(cyclobutylmethyl)-8-(dimethylamino)-3-[3-(6-fluoro-3-pyridinyl)-2-oxopropyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;1-(cyclobutylmethyl)-8-(dimethylamino)-3-[(2-methoxy-4-pyridinyl)methyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;1-(cyclobutylmethyl)-8-(dimethylamino)-3-[3-(2-methylpyrimidin-5-yl)-2-oxopropyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;1-[1-(cyclobutylmethyl)-8-(dimethylamino)-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-3-(5-methoxypyrimidin-2-yl)propan-2-one;8-(dimethylamino)-1-[(1-hydroxycyclobutyl)methyl]-3-(2-oxobutyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;2-[8-(dimethylamino)-1-[(1-hydroxycyclobutyl)methyl]-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]acetamide;5-[8-(dimethylamino)-1-(2-methylpropyl)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-4-oxopentanamide;2-[8-(dimethylamino)-2-oxo-3-(2-oxobutyl)-8-phenyl-1,3-diazaspiro[4.5]decan-1-yl]-N,N-dimethylacetamide;2-[8-(dimethylamino)-2-oxo-3-(2-oxo-3-pyrimidin-4-ylpropyl)-8-phenyl-1,3-diazaspiro[4.5]decan-1-yl]-N,N-dimethylacetamide;methyl 2-[3-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-2-oxopropyl]pyridine-4-carboxylate?
The canonical SMILES for 1-(cyclobutylmethyl)-8-(dimethylamino)-3-[3-(6-fluoro-3-pyridinyl)-2-oxopropyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;1-(cyclobutylmethyl)-8-(dimethylamino)-3-[(2-methoxy-4-pyridinyl)methyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;1-(cyclobutylmethyl)-8-(dimethylamino)-3-[3-(2-methylpyrimidin-5-yl)-2-oxopropyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;1-[1-(cyclobutylmethyl)-8-(dimethylamino)-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-3-(5-methoxypyrimidin-2-yl)propan-2-one;8-(dimethylamino)-1-[(1-hydroxycyclobutyl)methyl]-3-(2-oxobutyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;2-[8-(dimethylamino)-1-[(1-hydroxycyclobutyl)methyl]-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]acetamide;5-[8-(dimethylamino)-1-(2-methylpropyl)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-4-oxopentanamide;2-[8-(dimethylamino)-2-oxo-3-(2-oxobutyl)-8-phenyl-1,3-diazaspiro[4.5]decan-1-yl]-N,N-dimethylacetamide;2-[8-(dimethylamino)-2-oxo-3-(2-oxo-3-pyrimidin-4-ylpropyl)-8-phenyl-1,3-diazaspiro[4.5]decan-1-yl]-N,N-dimethylacetamide;methyl 2-[3-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-2-oxopropyl]pyridine-4-carboxylate is CC(C)CN1C(=O)N(CC(=O)CCC(N)=O)CC12CCC(c1ccccc1)(N(C)C)CC2.CCC(=O)CN1CC2(CCC(c3ccccc3)(N(C)C)CC2)N(CC(=O)N(C)C)C1=O.CCC(=O)CN1CC2(CCC(c3ccccc3)(N(C)C)CC2)N(CC2(O)CCC2)C1=O.CN(C)C(=O)CN1C(=O)N(CC(=O)Cc2ccncn2)CC12CCC(c1ccccc1)(N(C)C)CC2.CN(C)C1(c2ccccc2)CCC2(CC1)CN(CC(=O)Cc1ccc(F)nc1)C(=O)N2CC1CCC1.CN(C)C1(c2ccccc2)CCC2(CC1)CN(CC(N)=O)C(=O)N2CC1(O)CCC1.COC(=O)c1ccnc(CC(=O)CN2CC3(CCC(c4ccccc4)(N(C)C)CC3)N(CC3CCC3)C2=O)c1.COc1cc(CN2CC3(CCC(c4ccccc4)(N(C)C)CC3)N(CC3CCC3)C2=O)ccn1.COc1cnc(CC(=O)CN2CN(CC3CCC3)C3(CCC(c4ccccc4)(N(C)C)CC3)C2)nc1.Cc1ncc(CC(=O)CN2CC3(CCC(c4ccccc4)(N(C)C)CC3)N(CC3CCC3)C2=O)cn1.
What is the InChIKey of 1-(cyclobutylmethyl)-8-(dimethylamino)-3-[3-(6-fluoro-3-pyridinyl)-2-oxopropyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;1-(cyclobutylmethyl)-8-(dimethylamino)-3-[(2-methoxy-4-pyridinyl)methyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;1-(cyclobutylmethyl)-8-(dimethylamino)-3-[3-(2-methylpyrimidin-5-yl)-2-oxopropyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;1-[1-(cyclobutylmethyl)-8-(dimethylamino)-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-3-(5-methoxypyrimidin-2-yl)propan-2-one;8-(dimethylamino)-1-[(1-hydroxycyclobutyl)methyl]-3-(2-oxobutyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;2-[8-(dimethylamino)-1-[(1-hydroxycyclobutyl)methyl]-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]acetamide;5-[8-(dimethylamino)-1-(2-methylpropyl)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-4-oxopentanamide;2-[8-(dimethylamino)-2-oxo-3-(2-oxobutyl)-8-phenyl-1,3-diazaspiro[4.5]decan-1-yl]-N,N-dimethylacetamide;2-[8-(dimethylamino)-2-oxo-3-(2-oxo-3-pyrimidin-4-ylpropyl)-8-phenyl-1,3-diazaspiro[4.5]decan-1-yl]-N,N-dimethylacetamide;methyl 2-[3-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-2-oxopropyl]pyridine-4-carboxylate?
The InChIKey is KNCPOCUDQXMRDL-UHFFFAOYSA-N. The full InChI is InChI=1S/C31H40N4O4.C29H37FN4O2.C29H41N5O2.C29H39N5O2.C28H38N4O2.C27H36N6O3.C25H38N4O3.C25H37N3O3.C24H36N4O3.C23H34N4O3/c1-33(2)31(25-10-5-4-6-11-25)15-13-30(14-16-31)22-34(29(38)35(30)20-23-8-7-9-23)21-27(36)19-26-18-24(12-17-32-26)28(37)39-3;1-32(2)29(24-9-4-3-5-10-24)15-13-28(14-16-29)21-33(27(36)34(28)19-22-7-6-8-22)20-25(35)17-23-11-12-26(30)31-18-23;1-32(2)29(24-10-5-4-6-11-24)14-12-28(13-15-29)21-33(22-34(28)19-23-8-7-9-23)20-25(35)16-27-30-17-26(36-3)18-31-27;1-22-30-17-24(18-31-22)16-26(35)20-33-21-28(34(27(33)36)19-23-8-7-9-23)12-14-29(15-13-28,32(2)3)25-10-5-4-6-11-25;1-30(2)28(24-10-5-4-6-11-24)15-13-27(14-16-28)21-31(19-23-12-17-29-25(18-23)34-3)26(33)32(27)20-22-8-7-9-22;1-30(2)24(35)18-33-25(36)32(17-23(34)16-22-10-15-28-20-29-22)19-26(33)11-13-27(14-12-26,31(3)4)21-8-6-5-7-9-21;1-19(2)16-29-23(32)28(17-21(30)10-11-22(26)31)18-24(29)12-14-25(15-13-24,27(3)4)20-8-6-5-7-9-20;1-4-21(29)17-27-18-23(28(22(27)30)19-24(31)11-8-12-24)13-15-25(16-14-23,26(2)3)20-9-6-5-7-10-20;1-6-20(29)16-27-18-23(28(22(27)31)17-21(30)25(2)3)12-14-24(15-13-23,26(4)5)19-10-8-7-9-11-19;1-25(2)23(18-7-4-3-5-8-18)13-11-21(12-14-23)16-26(15-19(24)28)20(29)27(21)17-22(30)9-6-10-22/h4-6,10-12,17-18,23H,7-9,13-16,19-22H2,1-3H3;3-5,9-12,18,22H,6-8,13-17,19-21H2,1-2H3;4-6,10-11,17-18,23H,7-9,12-16,19-22H2,1-3H3;4-6,10-11,17-18,23H,7-9,12-16,19-21H2,1-3H3;4-6,10-12,17-18,22H,7-9,13-16,19-21H2,1-3H3;5-10,15,20H,11-14,16-19H2,1-4H3;5-9,19H,10-18H2,1-4H3,(H2,26,31);5-7,9-10,31H,4,8,11-19H2,1-3H3;7-11H,6,12-18H2,1-5H3;3-5,7-8,30H,6,9-17H2,1-2H3,(H2,24,28).
What are the key properties of 1-(cyclobutylmethyl)-8-(dimethylamino)-3-[3-(6-fluoro-3-pyridinyl)-2-oxopropyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;1-(cyclobutylmethyl)-8-(dimethylamino)-3-[(2-methoxy-4-pyridinyl)methyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;1-(cyclobutylmethyl)-8-(dimethylamino)-3-[3-(2-methylpyrimidin-5-yl)-2-oxopropyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;1-[1-(cyclobutylmethyl)-8-(dimethylamino)-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-3-(5-methoxypyrimidin-2-yl)propan-2-one;8-(dimethylamino)-1-[(1-hydroxycyclobutyl)methyl]-3-(2-oxobutyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;2-[8-(dimethylamino)-1-[(1-hydroxycyclobutyl)methyl]-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]acetamide;5-[8-(dimethylamino)-1-(2-methylpropyl)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-4-oxopentanamide;2-[8-(dimethylamino)-2-oxo-3-(2-oxobutyl)-8-phenyl-1,3-diazaspiro[4.5]decan-1-yl]-N,N-dimethylacetamide;2-[8-(dimethylamino)-2-oxo-3-(2-oxo-3-pyrimidin-4-ylpropyl)-8-phenyl-1,3-diazaspiro[4.5]decan-1-yl]-N,N-dimethylacetamide;methyl 2-[3-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-2-oxopropyl]pyridine-4-carboxylate?
1-(cyclobutylmethyl)-8-(dimethylamino)-3-[3-(6-fluoro-3-pyridinyl)-2-oxopropyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;1-(cyclobutylmethyl)-8-(dimethylamino)-3-[(2-methoxy-4-pyridinyl)methyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;1-(cyclobutylmethyl)-8-(dimethylamino)-3-[3-(2-methylpyrimidin-5-yl)-2-oxopropyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;1-[1-(cyclobutylmethyl)-8-(dimethylamino)-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-3-(5-methoxypyrimidin-2-yl)propan-2-one;8-(dimethylamino)-1-[(1-hydroxycyclobutyl)methyl]-3-(2-oxobutyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;2-[8-(dimethylamino)-1-[(1-hydroxycyclobutyl)methyl]-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]acetamide;5-[8-(dimethylamino)-1-(2-methylpropyl)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-4-oxopentanamide;2-[8-(dimethylamino)-2-oxo-3-(2-oxobutyl)-8-phenyl-1,3-diazaspiro[4.5]decan-1-yl]-N,N-dimethylacetamide;2-[8-(dimethylamino)-2-oxo-3-(2-oxo-3-pyrimidin-4-ylpropyl)-8-phenyl-1,3-diazaspiro[4.5]decan-1-yl]-N,N-dimethylacetamide;methyl 2-[3-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-2-oxopropyl]pyridine-4-carboxylate has a molecular weight of 4675.25 g/mol, XLogP of 34.78, 78 rotatable bonds, 4 hydrogen bond donors, and 48 hydrogen bond acceptors.
Where does this data come from?
All data for 1-(cyclobutylmethyl)-8-(dimethylamino)-3-[3-(6-fluoro-3-pyridinyl)-2-oxopropyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;1-(cyclobutylmethyl)-8-(dimethylamino)-3-[(2-methoxy-4-pyridinyl)methyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;1-(cyclobutylmethyl)-8-(dimethylamino)-3-[3-(2-methylpyrimidin-5-yl)-2-oxopropyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;1-[1-(cyclobutylmethyl)-8-(dimethylamino)-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-3-(5-methoxypyrimidin-2-yl)propan-2-one;8-(dimethylamino)-1-[(1-hydroxycyclobutyl)methyl]-3-(2-oxobutyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;2-[8-(dimethylamino)-1-[(1-hydroxycyclobutyl)methyl]-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]acetamide;5-[8-(dimethylamino)-1-(2-methylpropyl)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-4-oxopentanamide;2-[8-(dimethylamino)-2-oxo-3-(2-oxobutyl)-8-phenyl-1,3-diazaspiro[4.5]decan-1-yl]-N,N-dimethylacetamide;2-[8-(dimethylamino)-2-oxo-3-(2-oxo-3-pyrimidin-4-ylpropyl)-8-phenyl-1,3-diazaspiro[4.5]decan-1-yl]-N,N-dimethylacetamide;methyl 2-[3-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-2-oxopropyl]pyridine-4-carboxylate is sourced from PubChem (CID 159182824), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).