1-[[6-(3-azabicyclo[3.1.0]hexan-3-yl)-2-methyl-3-pyridinyl]methyl]-N-[(5R)-1,3-dimethyl-6,7-dihydro-5H-cyclopenta[c]pyridin-5-yl]-3-methylpyrazole-4-carboxamide;1-[[2-(3-azabicyclo[3.1.0]hexan-3-yl)-4-methylpyrimidin-5-yl]methyl]-N-[(5R)-1,3-dimethyl-6,7-dihydro-5H-cyclopenta[c]pyridin-5-yl]pyrazole-4-carboxamide;1-[[2-(3-azabicyclo[3.1.0]hexan-3-yl)-4-methylpyrimidin-5-yl]methyl]-N-[(5R)-1,3-dimethyl-6,7-dihydro-5H-cyclopenta[c]pyridin-5-yl]triazole-4-carboxamide;1-[[2-(3-azabicyclo[3.1.0]hexan-3-yl)-4-methylpyrimidin-5-yl]methyl]-N-[(5R)-1-methyl-6,7-dihydro-5H-cyclopenta[c]pyridin-5-yl]pyrazole-4-carboxamide;1-[[2-(3-azabicyclo[3.1.0]hexan-3-yl)-4-methylpyrimidin-5-yl]methyl]-N-[(5R)-1-methyl-6,7-dihydro-5H-cyclopenta[c]pyridin-5-yl]triazole-4-carboxamide;1-[[6-(5-azaspiro[2.4]heptan-5-yl)-2-methyl-3-pyridinyl]methyl]-N-[(5R)-1-methyl-6,7-dihydro-5H-cyclopenta[c]pyridin-5-yl]pyrazole-4-carboxamide;1-[[6-[(1R,5S)-6-cyano-3-azabicyclo[3.1.0]hexan-3-yl]-2-methyl-3-pyridinyl]methyl]-N-[(5R)-1-methyl-6,7-dihydro-5H-cyclopenta[c]pyridin-5-yl]pyrazole-4-carboxamide;1-[[6-(6,6-difluoro-3-azabicyclo[3.1.0]hexan-3-yl)-2-methyl-3-pyridinyl]methyl]-N-[(5R)-1,3-dimethyl-6,7-dihydro-5H-cyclopenta[c]pyridin-5-yl]pyrazole-4-carboxamide;1-[[6-[(1R,5S)-6-(hydroxymethyl)-3-azabicyclo[3.1.0]hexan-3-yl]-2-methyl-3-pyridinyl]methyl]-N-[(5R)-1-methyl-6,7-dihydro-5H-cyclopenta[c]pyridin-5-yl]pyrazole-4-carboxamide

C227H257F2N61O10 — CID 159185333

IUPAC1-[[6-(3-azabicyclo[3.1.0]hexan-3-yl)-2-methyl-3-pyridinyl]methyl]-N-[(5R)-1,3-dimethyl-6,7-dihydro-5H-cyclopenta[c]pyridin-5-yl]-3-methylpyrazole-4-carboxamide;1-[[2-(3-azabicyclo[3.1.0]hexan-3-yl)-4-methylpyrimidin-5-yl]methyl]-N-[(5R)-1,3-dimethyl-6,7-dihydro-5H-cyclopenta[c]pyridin-5-yl]pyrazole-4-carboxamide;1-[[2-(3-azabicyclo[3.1.0]hexan-3-yl)-4-methylpyrimidin-5-yl]methyl]-N-[(5R)-1,3-dimethyl-6,7-dihydro-5H-cyclopenta[c]pyridin-5-yl]triazole-4-carboxamide;1-[[2-(3-azabicyclo[3.1.0]hexan-3-yl)-4-methylpyrimidin-5-yl]methyl]-N-[(5R)-1-methyl-6,7-dihydro-5H-cyclopenta[c]pyridin-5-yl]pyrazole-4-carboxamide;1-[[2-(3-azabicyclo[3.1.0]hexan-3-yl)-4-methylpyrimidin-5-yl]methyl]-N-[(5R)-1-methyl-6,7-dihydro-5H-cyclopenta[c]pyridin-5-yl]triazole-4-carboxamide;1-[[6-(5-azaspiro[2.4]heptan-5-yl)-2-methyl-3-pyridinyl]methyl]-N-[(5R)-1-methyl-6,7-dihydro-5H-cyclopenta[c]pyridin-5-yl]pyrazole-4-carboxamide;1-[[6-[(1R,5S)-6-cyano-3-azabicyclo[3.1.0]hexan-3-yl]-2-methyl-3-pyridinyl]methyl]-N-[(5R)-1-methyl-6,7-dihydro-5H-cyclopenta[c]pyridin-5-yl]pyrazole-4-carboxamide;1-[[6-(6,6-difluoro-3-azabicyclo[3.1.0]hexan-3-yl)-2-methyl-3-pyridinyl]methyl]-N-[(5R)-1,3-dimethyl-6,7-dihydro-5H-cyclopenta[c]pyridin-5-yl]pyrazole-4-carboxamide;1-[[6-[(1R,5S)-6-(hydroxymethyl)-3-azabicyclo[3.1.0]hexan-3-yl]-2-methyl-3-pyridinyl]methyl]-N-[(5R)-1-methyl-6,7-dihydro-5H-cyclopenta[c]pyridin-5-yl]pyrazole-4-carboxamide
SMILESCc1cc2c(c(C)n1)CC[C@H]2NC(=O)c1cn(Cc2ccc(N3CC4CC4C3)nc2C)nc1C.Cc1cc2c(c(C)n1)CC[C@H]2NC(=O)c1cn(Cc2cnc(N3CC4CC4C3)nc2C)nn1.Cc1cc2c(c(C)n1)CC[C@H]2NC(=O)c1cnn(Cc2ccc(N3CC4C(C3)C4(F)F)nc2C)c1.Cc1cc2c(c(C)n1)CC[C@H]2NC(=O)c1cnn(Cc2cnc(N3CC4CC4C3)nc2C)c1.Cc1nc(N2CC3CC3C2)ncc1Cn1cc(C(=O)N[C@@H]2CCc3c2ccnc3C)cn1.Cc1nc(N2CC3CC3C2)ncc1Cn1cc(C(=O)N[C@@H]2CCc3c2ccnc3C)nn1.Cc1nc(N2CCC3(CC3)C2)ccc1Cn1cc(C(=O)N[C@@H]2CCc3c2ccnc3C)cn1.Cc1nc(N2C[C@@H]3C(C#N)[C@@H]3C2)ccc1Cn1cc(C(=O)N[C@@H]2CCc3c2ccnc3C)cn1.Cc1nc(N2C[C@@H]3C(CO)[C@@H]3C2)ccc1Cn1cc(C(=O)N[C@@H]2CCc3c2ccnc3C)cn1
InChIInChI=1S/C27H32N6O.C26H28F2N6O.C26H27N7O.C26H30N6O2.C26H30N6O.C25H29N7O.C24H28N8O.C24H27N7O.C23H26N8O/c1-15-9-23-22(17(3)28-15)6-7-25(23)30-27(34)24-14-33(31-18(24)4)13-19-5-8-26(29-16(19)2)32-11-20-10-21(20)12-32;1-14-8-20-19(16(3)30-14)5-6-23(20)32-25(35)18-9-29-34(11-18)10-17-4-7-24(31-15(17)2)33-12-21-22(13-33)26(21,27)28;1-15-17(3-6-25(30-15)32-13-22-21(9-27)23(22)14-32)11-33-12-18(10-29-33)26(34)31-24-5-4-19-16(2)28-8-7-20(19)24;1-15-17(3-6-25(29-15)31-12-21-22(13-31)23(21)14-33)10-32-11-18(9-28-32)26(34)30-24-5-4-19-16(2)27-8-7-20(19)24;1-17-19(3-6-24(29-17)31-12-10-26(16-31)8-9-26)14-32-15-20(13-28-32)25(33)30-23-5-4-21-18(2)27-11-7-22(21)23;1-14-6-22-21(16(3)28-14)4-5-23(22)30-24(33)20-9-27-32(13-20)12-19-8-26-25(29-15(19)2)31-10-17-7-18(17)11-31;1-13-6-20-19(15(3)26-13)4-5-21(20)28-23(33)22-12-32(30-29-22)11-18-8-25-24(27-14(18)2)31-9-16-7-17(16)10-31;1-14-18(8-26-24(28-14)30-10-16-7-17(16)11-30)12-31-13-19(9-27-31)23(32)29-22-4-3-20-15(2)25-6-5-21(20)22;1-13-17(8-25-23(26-13)30-9-15-7-16(15)10-30)11-31-12-21(28-29-31)22(32)27-20-4-3-18-14(2)24-6-5-19(18)20/h5,8-9,14,20-21,25H,6-7,10-13H2,1-4H3,(H,30,34);4,7-9,11,21-23H,5-6,10,12-13H2,1-3H3,(H,32,35);3,6-8,10,12,21-24H,4-5,11,13-14H2,1-2H3,(H,31,34);3,6-9,11,21-24,33H,4-5,10,12-14H2,1-2H3,(H,30,34);3,6-7,11,13,15,23H,4-5,8-10,12,14,16H2,1-2H3,(H,30,33);6,8-9,13,17-18,23H,4-5,7,10-12H2,1-3H3,(H,30,33);6,8,12,16-17,21H,4-5,7,9-11H2,1-3H3,(H,28,33);5-6,8-9,13,16-17,22H,3-4,7,10-12H2,1-2H3,(H,29,32);5-6,8,12,15-16,20H,3-4,7,9-11H2,1-2H3,(H,27,32)/t20?,21?,25-;21?,22?,23-;21?,22-,23+,24-;21-,22+,23?,24-;23-;17?,18?,23-;16?,17?,21-;16?,17?,22-;15?,16?,20-/m111111111/s1
InChIKeyKNKNOALVVKLGIV-SEQOBTOLSA-N
MW4037.97 g/mol
LogP26.56
Rot. Bonds46

About 1-[[6-(3-azabicyclo[3.1.0]hexan-3-yl)-2-methyl-3-pyridinyl]methyl]-N-[(5R)-1,3-dimethyl-6,7-dihydro-5H-cyclopenta[c]pyridin-5-yl]-3-methylpyrazole-4-carboxamide;1-[[2-(3-azabicyclo[3.1.0]hexan-3-yl)-4-methylpyrimidin-5-yl]methyl]-N-[(5R)-1,3-dimethyl-6,7-dihydro-5H-cyclopenta[c]pyridin-5-yl]pyrazole-4-carboxamide;1-[[2-(3-azabicyclo[3.1.0]hexan-3-yl)-4-methylpyrimidin-5-yl]methyl]-N-[(5R)-1,3-dimethyl-6,7-dihydro-5H-cyclopenta[c]pyridin-5-yl]triazole-4-carboxamide;1-[[2-(3-azabicyclo[3.1.0]hexan-3-yl)-4-methylpyrimidin-5-yl]methyl]-N-[(5R)-1-methyl-6,7-dihydro-5H-cyclopenta[c]pyridin-5-yl]pyrazole-4-carboxamide;1-[[2-(3-azabicyclo[3.1.0]hexan-3-yl)-4-methylpyrimidin-5-yl]methyl]-N-[(5R)-1-methyl-6,7-dihydro-5H-cyclopenta[c]pyridin-5-yl]triazole-4-carboxamide;1-[[6-(5-azaspiro[2.4]heptan-5-yl)-2-methyl-3-pyridinyl]methyl]-N-[(5R)-1-methyl-6,7-dihydro-5H-cyclopenta[c]pyridin-5-yl]pyrazole-4-carboxamide;1-[[6-[(1R,5S)-6-cyano-3-azabicyclo[3.1.0]hexan-3-yl]-2-methyl-3-pyridinyl]methyl]-N-[(5R)-1-methyl-6,7-dihydro-5H-cyclopenta[c]pyridin-5-yl]pyrazole-4-carboxamide;1-[[6-(6,6-difluoro-3-azabicyclo[3.1.0]hexan-3-yl)-2-methyl-3-pyridinyl]methyl]-N-[(5R)-1,3-dimethyl-6,7-dihydro-5H-cyclopenta[c]pyridin-5-yl]pyrazole-4-carboxamide;1-[[6-[(1R,5S)-6-(hydroxymethyl)-3-azabicyclo[3.1.0]hexan-3-yl]-2-methyl-3-pyridinyl]methyl]-N-[(5R)-1-methyl-6,7-dihydro-5H-cyclopenta[c]pyridin-5-yl]pyrazole-4-carboxamide

1-[[6-(3-azabicyclo[3.1.0]hexan-3-yl)-2-methyl-3-pyridinyl]methyl]-N-[(5R)-1,3-dimethyl-6,7-dihydro-5H-cyclopenta[c]pyridin-5-yl]-3-methylpyrazole-4-carboxamide;1-[[2-(3-azabicyclo[3.1.0]hexan-3-yl)-4-methylpyrimidin-5-yl]methyl]-N-[(5R)-1,3-dimethyl-6,7-dihydro-5H-cyclopenta[c]pyridin-5-yl]pyrazole-4-carboxamide;1-[[2-(3-azabicyclo[3.1.0]hexan-3-yl)-4-methylpyrimidin-5-yl]methyl]-N-[(5R)-1,3-dimethyl-6,7-dihydro-5H-cyclopenta[c]pyridin-5-yl]triazole-4-carboxamide;1-[[2-(3-azabicyclo[3.1.0]hexan-3-yl)-4-methylpyrimidin-5-yl]methyl]-N-[(5R)-1-methyl-6,7-dihydro-5H-cyclopenta[c]pyridin-5-yl]pyrazole-4-carboxamide;1-[[2-(3-azabicyclo[3.1.0]hexan-3-yl)-4-methylpyrimidin-5-yl]methyl]-N-[(5R)-1-methyl-6,7-dihydro-5H-cyclopenta[c]pyridin-5-yl]triazole-4-carboxamide;1-[[6-(5-azaspiro[2.4]heptan-5-yl)-2-methyl-3-pyridinyl]methyl]-N-[(5R)-1-methyl-6,7-dihydro-5H-cyclopenta[c]pyridin-5-yl]pyrazole-4-carboxamide;1-[[6-[(1R,5S)-6-cyano-3-azabicyclo[3.1.0]hexan-3-yl]-2-methyl-3-pyridinyl]methyl]-N-[(5R)-1-methyl-6,7-dihydro-5H-cyclopenta[c]pyridin-5-yl]pyrazole-4-carboxamide;1-[[6-(6,6-difluoro-3-azabicyclo[3.1.0]hexan-3-yl)-2-methyl-3-pyridinyl]methyl]-N-[(5R)-1,3-dimethyl-6,7-dihydro-5H-cyclopenta[c]pyridin-5-yl]pyrazole-4-carboxamide;1-[[6-[(1R,5S)-6-(hydroxymethyl)-3-azabicyclo[3.1.0]hexan-3-yl]-2-methyl-3-pyridinyl]methyl]-N-[(5R)-1-methyl-6,7-dihydro-5H-cyclopenta[c]pyridin-5-yl]pyrazole-4-carboxamide (PubChem CID 159185333) has the molecular formula C227H257F2N61O10 and a molecular weight of 4037.97 g/mol. Its IUPAC name is 1-[[6-(3-azabicyclo[3.1.0]hexan-3-yl)-2-methyl-3-pyridinyl]methyl]-N-[(5R)-1,3-dimethyl-6,7-dihydro-5H-cyclopenta[c]pyridin-5-yl]-3-methylpyrazole-4-carboxamide;1-[[2-(3-azabicyclo[3.1.0]hexan-3-yl)-4-methylpyrimidin-5-yl]methyl]-N-[(5R)-1,3-dimethyl-6,7-dihydro-5H-cyclopenta[c]pyridin-5-yl]pyrazole-4-carboxamide;1-[[2-(3-azabicyclo[3.1.0]hexan-3-yl)-4-methylpyrimidin-5-yl]methyl]-N-[(5R)-1,3-dimethyl-6,7-dihydro-5H-cyclopenta[c]pyridin-5-yl]triazole-4-carboxamide;1-[[2-(3-azabicyclo[3.1.0]hexan-3-yl)-4-methylpyrimidin-5-yl]methyl]-N-[(5R)-1-methyl-6,7-dihydro-5H-cyclopenta[c]pyridin-5-yl]pyrazole-4-carboxamide;1-[[2-(3-azabicyclo[3.1.0]hexan-3-yl)-4-methylpyrimidin-5-yl]methyl]-N-[(5R)-1-methyl-6,7-dihydro-5H-cyclopenta[c]pyridin-5-yl]triazole-4-carboxamide;1-[[6-(5-azaspiro[2.4]heptan-5-yl)-2-methyl-3-pyridinyl]methyl]-N-[(5R)-1-methyl-6,7-dihydro-5H-cyclopenta[c]pyridin-5-yl]pyrazole-4-carboxamide;1-[[6-[(1R,5S)-6-cyano-3-azabicyclo[3.1.0]hexan-3-yl]-2-methyl-3-pyridinyl]methyl]-N-[(5R)-1-methyl-6,7-dihydro-5H-cyclopenta[c]pyridin-5-yl]pyrazole-4-carboxamide;1-[[6-(6,6-difluoro-3-azabicyclo[3.1.0]hexan-3-yl)-2-methyl-3-pyridinyl]methyl]-N-[(5R)-1,3-dimethyl-6,7-dihydro-5H-cyclopenta[c]pyridin-5-yl]pyrazole-4-carboxamide;1-[[6-[(1R,5S)-6-(hydroxymethyl)-3-azabicyclo[3.1.0]hexan-3-yl]-2-methyl-3-pyridinyl]methyl]-N-[(5R)-1-methyl-6,7-dihydro-5H-cyclopenta[c]pyridin-5-yl]pyrazole-4-carboxamide.

Molecular Properties

Compound Name1-[[6-(3-azabicyclo[3.1.0]hexan-3-yl)-2-methyl-3-pyridinyl]methyl]-N-[(5R)-1,3-dimethyl-6,7-dihydro-5H-cyclopenta[c]pyridin-5-yl]-3-methylpyrazole-4-carboxamide;1-[[2-(3-azabicyclo[3.1.0]hexan-3-yl)-4-methylpyrimidin-5-yl]methyl]-N-[(5R)-1,3-dimethyl-6,7-dihydro-5H-cyclopenta[c]pyridin-5-yl]pyrazole-4-carboxamide;1-[[2-(3-azabicyclo[3.1.0]hexan-3-yl)-4-methylpyrimidin-5-yl]methyl]-N-[(5R)-1,3-dimethyl-6,7-dihydro-5H-cyclopenta[c]pyridin-5-yl]triazole-4-carboxamide;1-[[2-(3-azabicyclo[3.1.0]hexan-3-yl)-4-methylpyrimidin-5-yl]methyl]-N-[(5R)-1-methyl-6,7-dihydro-5H-cyclopenta[c]pyridin-5-yl]pyrazole-4-carboxamide;1-[[2-(3-azabicyclo[3.1.0]hexan-3-yl)-4-methylpyrimidin-5-yl]methyl]-N-[(5R)-1-methyl-6,7-dihydro-5H-cyclopenta[c]pyridin-5-yl]triazole-4-carboxamide;1-[[6-(5-azaspiro[2.4]heptan-5-yl)-2-methyl-3-pyridinyl]methyl]-N-[(5R)-1-methyl-6,7-dihydro-5H-cyclopenta[c]pyridin-5-yl]pyrazole-4-carboxamide;1-[[6-[(1R,5S)-6-cyano-3-azabicyclo[3.1.0]hexan-3-yl]-2-methyl-3-pyridinyl]methyl]-N-[(5R)-1-methyl-6,7-dihydro-5H-cyclopenta[c]pyridin-5-yl]pyrazole-4-carboxamide;1-[[6-(6,6-difluoro-3-azabicyclo[3.1.0]hexan-3-yl)-2-methyl-3-pyridinyl]methyl]-N-[(5R)-1,3-dimethyl-6,7-dihydro-5H-cyclopenta[c]pyridin-5-yl]pyrazole-4-carboxamide;1-[[6-[(1R,5S)-6-(hydroxymethyl)-3-azabicyclo[3.1.0]hexan-3-yl]-2-methyl-3-pyridinyl]methyl]-N-[(5R)-1-methyl-6,7-dihydro-5H-cyclopenta[c]pyridin-5-yl]pyrazole-4-carboxamide
PubChem CID159185333
Molecular FormulaC227H257F2N61O10
Molecular Weight4037.97 g/mol
Exact Mass4035.14
IUPAC Name1-[[6-(3-azabicyclo[3.1.0]hexan-3-yl)-2-methyl-3-pyridinyl]methyl]-N-[(5R)-1,3-dimethyl-6,7-dihydro-5H-cyclopenta[c]pyridin-5-yl]-3-methylpyrazole-4-carboxamide;1-[[2-(3-azabicyclo[3.1.0]hexan-3-yl)-4-methylpyrimidin-5-yl]methyl]-N-[(5R)-1,3-dimethyl-6,7-dihydro-5H-cyclopenta[c]pyridin-5-yl]pyrazole-4-carboxamide;1-[[2-(3-azabicyclo[3.1.0]hexan-3-yl)-4-methylpyrimidin-5-yl]methyl]-N-[(5R)-1,3-dimethyl-6,7-dihydro-5H-cyclopenta[c]pyridin-5-yl]triazole-4-carboxamide;1-[[2-(3-azabicyclo[3.1.0]hexan-3-yl)-4-methylpyrimidin-5-yl]methyl]-N-[(5R)-1-methyl-6,7-dihydro-5H-cyclopenta[c]pyridin-5-yl]pyrazole-4-carboxamide;1-[[2-(3-azabicyclo[3.1.0]hexan-3-yl)-4-methylpyrimidin-5-yl]methyl]-N-[(5R)-1-methyl-6,7-dihydro-5H-cyclopenta[c]pyridin-5-yl]triazole-4-carboxamide;1-[[6-(5-azaspiro[2.4]heptan-5-yl)-2-methyl-3-pyridinyl]methyl]-N-[(5R)-1-methyl-6,7-dihydro-5H-cyclopenta[c]pyridin-5-yl]pyrazole-4-carboxamide;1-[[6-[(1R,5S)-6-cyano-3-azabicyclo[3.1.0]hexan-3-yl]-2-methyl-3-pyridinyl]methyl]-N-[(5R)-1-methyl-6,7-dihydro-5H-cyclopenta[c]pyridin-5-yl]pyrazole-4-carboxamide;1-[[6-(6,6-difluoro-3-azabicyclo[3.1.0]hexan-3-yl)-2-methyl-3-pyridinyl]methyl]-N-[(5R)-1,3-dimethyl-6,7-dihydro-5H-cyclopenta[c]pyridin-5-yl]pyrazole-4-carboxamide;1-[[6-[(1R,5S)-6-(hydroxymethyl)-3-azabicyclo[3.1.0]hexan-3-yl]-2-methyl-3-pyridinyl]methyl]-N-[(5R)-1-methyl-6,7-dihydro-5H-cyclopenta[c]pyridin-5-yl]pyrazole-4-carboxamide
SMILESCc1cc2c(c(C)n1)CC[C@H]2NC(=O)c1cn(Cc2ccc(N3CC4CC4C3)nc2C)nc1C.Cc1cc2c(c(C)n1)CC[C@H]2NC(=O)c1cn(Cc2cnc(N3CC4CC4C3)nc2C)nn1.Cc1cc2c(c(C)n1)CC[C@H]2NC(=O)c1cnn(Cc2ccc(N3CC4C(C3)C4(F)F)nc2C)c1.Cc1cc2c(c(C)n1)CC[C@H]2NC(=O)c1cnn(Cc2cnc(N3CC4CC4C3)nc2C)c1.Cc1nc(N2CC3CC3C2)ncc1Cn1cc(C(=O)N[C@@H]2CCc3c2ccnc3C)cn1.Cc1nc(N2CC3CC3C2)ncc1Cn1cc(C(=O)N[C@@H]2CCc3c2ccnc3C)nn1.Cc1nc(N2CCC3(CC3)C2)ccc1Cn1cc(C(=O)N[C@@H]2CCc3c2ccnc3C)cn1.Cc1nc(N2C[C@@H]3C(C#N)[C@@H]3C2)ccc1Cn1cc(C(=O)N[C@@H]2CCc3c2ccnc3C)cn1.Cc1nc(N2C[C@@H]3C(CO)[C@@H]3C2)ccc1Cn1cc(C(=O)N[C@@H]2CCc3c2ccnc3C)cn1
InChIInChI=1S/C27H32N6O.C26H28F2N6O.C26H27N7O.C26H30N6O2.C26H30N6O.C25H29N7O.C24H28N8O.C24H27N7O.C23H26N8O/c1-15-9-23-22(17(3)28-15)6-7-25(23)30-27(34)24-14-33(31-18(24)4)13-19-5-8-26(29-16(19)2)32-11-20-10-21(20)12-32;1-14-8-20-19(16(3)30-14)5-6-23(20)32-25(35)18-9-29-34(11-18)10-17-4-7-24(31-15(17)2)33-12-21-22(13-33)26(21,27)28;1-15-17(3-6-25(30-15)32-13-22-21(9-27)23(22)14-32)11-33-12-18(10-29-33)26(34)31-24-5-4-19-16(2)28-8-7-20(19)24;1-15-17(3-6-25(29-15)31-12-21-22(13-31)23(21)14-33)10-32-11-18(9-28-32)26(34)30-24-5-4-19-16(2)27-8-7-20(19)24;1-17-19(3-6-24(29-17)31-12-10-26(16-31)8-9-26)14-32-15-20(13-28-32)25(33)30-23-5-4-21-18(2)27-11-7-22(21)23;1-14-6-22-21(16(3)28-14)4-5-23(22)30-24(33)20-9-27-32(13-20)12-19-8-26-25(29-15(19)2)31-10-17-7-18(17)11-31;1-13-6-20-19(15(3)26-13)4-5-21(20)28-23(33)22-12-32(30-29-22)11-18-8-25-24(27-14(18)2)31-9-16-7-17(16)10-31;1-14-18(8-26-24(28-14)30-10-16-7-17(16)11-30)12-31-13-19(9-27-31)23(32)29-22-4-3-20-15(2)25-6-5-21(20)22;1-13-17(8-25-23(26-13)30-9-15-7-16(15)10-30)11-31-12-21(28-29-31)22(32)27-20-4-3-18-14(2)24-6-5-19(18)20/h5,8-9,14,20-21,25H,6-7,10-13H2,1-4H3,(H,30,34);4,7-9,11,21-23H,5-6,10,12-13H2,1-3H3,(H,32,35);3,6-8,10,12,21-24H,4-5,11,13-14H2,1-2H3,(H,31,34);3,6-9,11,21-24,33H,4-5,10,12-14H2,1-2H3,(H,30,34);3,6-7,11,13,15,23H,4-5,8-10,12,14,16H2,1-2H3,(H,30,33);6,8-9,13,17-18,23H,4-5,7,10-12H2,1-3H3,(H,30,33);6,8,12,16-17,21H,4-5,7,9-11H2,1-3H3,(H,28,33);5-6,8-9,13,16-17,22H,3-4,7,10-12H2,1-2H3,(H,29,32);5-6,8,12,15-16,20H,3-4,7,9-11H2,1-2H3,(H,27,32)/t20?,21?,25-;21?,22?,23-;21?,22-,23+,24-;21-,22+,23?,24-;23-;17?,18?,23-;16?,17?,21-;16?,17?,22-;15?,16?,20-/m111111111/s1
InChIKeyKNKNOALVVKLGIV-SEQOBTOLSA-N
XLogP26.56
TPSA804.82 Ų
H-Bond Donors10
H-Bond Acceptors62
Rotatable Bonds46
Heavy Atoms300
Complexity—

Lipinski Rule of Five

4 violations

RuleValue
MW ≤ 5004037.97
LogP ≤ 526.56
H-Bond Donors ≤ 510
H-Bond Acceptors ≤ 1062

Analyze 1-[[6-(3-azabicyclo[3.1.0]hexan-3-yl)-2-methyl-3-pyridinyl]methyl]-N-[(5R)-1,3-dimethyl-6,7-dihydro-5H-cyclopenta[c]pyridin-5-yl]-3-methylpyrazole-4-carboxamide;1-[[2-(3-azabicyclo[3.1.0]hexan-3-yl)-4-methylpyrimidin-5-yl]methyl]-N-[(5R)-1,3-dimethyl-6,7-dihydro-5H-cyclopenta[c]pyridin-5-yl]pyrazole-4-carboxamide;1-[[2-(3-azabicyclo[3.1.0]hexan-3-yl)-4-methylpyrimidin-5-yl]methyl]-N-[(5R)-1,3-dimethyl-6,7-dihydro-5H-cyclopenta[c]pyridin-5-yl]triazole-4-carboxamide;1-[[2-(3-azabicyclo[3.1.0]hexan-3-yl)-4-methylpyrimidin-5-yl]methyl]-N-[(5R)-1-methyl-6,7-dihydro-5H-cyclopenta[c]pyridin-5-yl]pyrazole-4-carboxamide;1-[[2-(3-azabicyclo[3.1.0]hexan-3-yl)-4-methylpyrimidin-5-yl]methyl]-N-[(5R)-1-methyl-6,7-dihydro-5H-cyclopenta[c]pyridin-5-yl]triazole-4-carboxamide;1-[[6-(5-azaspiro[2.4]heptan-5-yl)-2-methyl-3-pyridinyl]methyl]-N-[(5R)-1-methyl-6,7-dihydro-5H-cyclopenta[c]pyridin-5-yl]pyrazole-4-carboxamide;1-[[6-[(1R,5S)-6-cyano-3-azabicyclo[3.1.0]hexan-3-yl]-2-methyl-3-pyridinyl]methyl]-N-[(5R)-1-methyl-6,7-dihydro-5H-cyclopenta[c]pyridin-5-yl]pyrazole-4-carboxamide;1-[[6-(6,6-difluoro-3-azabicyclo[3.1.0]hexan-3-yl)-2-methyl-3-pyridinyl]methyl]-N-[(5R)-1,3-dimethyl-6,7-dihydro-5H-cyclopenta[c]pyridin-5-yl]pyrazole-4-carboxamide;1-[[6-[(1R,5S)-6-(hydroxymethyl)-3-azabicyclo[3.1.0]hexan-3-yl]-2-methyl-3-pyridinyl]methyl]-N-[(5R)-1-methyl-6,7-dihydro-5H-cyclopenta[c]pyridin-5-yl]pyrazole-4-carboxamide with MolForge

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Frequently Asked Questions

What is the IUPAC name of 1-[[6-(3-azabicyclo[3.1.0]hexan-3-yl)-2-methyl-3-pyridinyl]methyl]-N-[(5R)-1,3-dimethyl-6,7-dihydro-5H-cyclopenta[c]pyridin-5-yl]-3-methylpyrazole-4-carboxamide;1-[[2-(3-azabicyclo[3.1.0]hexan-3-yl)-4-methylpyrimidin-5-yl]methyl]-N-[(5R)-1,3-dimethyl-6,7-dihydro-5H-cyclopenta[c]pyridin-5-yl]pyrazole-4-carboxamide;1-[[2-(3-azabicyclo[3.1.0]hexan-3-yl)-4-methylpyrimidin-5-yl]methyl]-N-[(5R)-1,3-dimethyl-6,7-dihydro-5H-cyclopenta[c]pyridin-5-yl]triazole-4-carboxamide;1-[[2-(3-azabicyclo[3.1.0]hexan-3-yl)-4-methylpyrimidin-5-yl]methyl]-N-[(5R)-1-methyl-6,7-dihydro-5H-cyclopenta[c]pyridin-5-yl]pyrazole-4-carboxamide;1-[[2-(3-azabicyclo[3.1.0]hexan-3-yl)-4-methylpyrimidin-5-yl]methyl]-N-[(5R)-1-methyl-6,7-dihydro-5H-cyclopenta[c]pyridin-5-yl]triazole-4-carboxamide;1-[[6-(5-azaspiro[2.4]heptan-5-yl)-2-methyl-3-pyridinyl]methyl]-N-[(5R)-1-methyl-6,7-dihydro-5H-cyclopenta[c]pyridin-5-yl]pyrazole-4-carboxamide;1-[[6-[(1R,5S)-6-cyano-3-azabicyclo[3.1.0]hexan-3-yl]-2-methyl-3-pyridinyl]methyl]-N-[(5R)-1-methyl-6,7-dihydro-5H-cyclopenta[c]pyridin-5-yl]pyrazole-4-carboxamide;1-[[6-(6,6-difluoro-3-azabicyclo[3.1.0]hexan-3-yl)-2-methyl-3-pyridinyl]methyl]-N-[(5R)-1,3-dimethyl-6,7-dihydro-5H-cyclopenta[c]pyridin-5-yl]pyrazole-4-carboxamide;1-[[6-[(1R,5S)-6-(hydroxymethyl)-3-azabicyclo[3.1.0]hexan-3-yl]-2-methyl-3-pyridinyl]methyl]-N-[(5R)-1-methyl-6,7-dihydro-5H-cyclopenta[c]pyridin-5-yl]pyrazole-4-carboxamide?
The IUPAC name of 1-[[6-(3-azabicyclo[3.1.0]hexan-3-yl)-2-methyl-3-pyridinyl]methyl]-N-[(5R)-1,3-dimethyl-6,7-dihydro-5H-cyclopenta[c]pyridin-5-yl]-3-methylpyrazole-4-carboxamide;1-[[2-(3-azabicyclo[3.1.0]hexan-3-yl)-4-methylpyrimidin-5-yl]methyl]-N-[(5R)-1,3-dimethyl-6,7-dihydro-5H-cyclopenta[c]pyridin-5-yl]pyrazole-4-carboxamide;1-[[2-(3-azabicyclo[3.1.0]hexan-3-yl)-4-methylpyrimidin-5-yl]methyl]-N-[(5R)-1,3-dimethyl-6,7-dihydro-5H-cyclopenta[c]pyridin-5-yl]triazole-4-carboxamide;1-[[2-(3-azabicyclo[3.1.0]hexan-3-yl)-4-methylpyrimidin-5-yl]methyl]-N-[(5R)-1-methyl-6,7-dihydro-5H-cyclopenta[c]pyridin-5-yl]pyrazole-4-carboxamide;1-[[2-(3-azabicyclo[3.1.0]hexan-3-yl)-4-methylpyrimidin-5-yl]methyl]-N-[(5R)-1-methyl-6,7-dihydro-5H-cyclopenta[c]pyridin-5-yl]triazole-4-carboxamide;1-[[6-(5-azaspiro[2.4]heptan-5-yl)-2-methyl-3-pyridinyl]methyl]-N-[(5R)-1-methyl-6,7-dihydro-5H-cyclopenta[c]pyridin-5-yl]pyrazole-4-carboxamide;1-[[6-[(1R,5S)-6-cyano-3-azabicyclo[3.1.0]hexan-3-yl]-2-methyl-3-pyridinyl]methyl]-N-[(5R)-1-methyl-6,7-dihydro-5H-cyclopenta[c]pyridin-5-yl]pyrazole-4-carboxamide;1-[[6-(6,6-difluoro-3-azabicyclo[3.1.0]hexan-3-yl)-2-methyl-3-pyridinyl]methyl]-N-[(5R)-1,3-dimethyl-6,7-dihydro-5H-cyclopenta[c]pyridin-5-yl]pyrazole-4-carboxamide;1-[[6-[(1R,5S)-6-(hydroxymethyl)-3-azabicyclo[3.1.0]hexan-3-yl]-2-methyl-3-pyridinyl]methyl]-N-[(5R)-1-methyl-6,7-dihydro-5H-cyclopenta[c]pyridin-5-yl]pyrazole-4-carboxamide (CID 159185333) is 1-[[6-(3-azabicyclo[3.1.0]hexan-3-yl)-2-methyl-3-pyridinyl]methyl]-N-[(5R)-1,3-dimethyl-6,7-dihydro-5H-cyclopenta[c]pyridin-5-yl]-3-methylpyrazole-4-carboxamide;1-[[2-(3-azabicyclo[3.1.0]hexan-3-yl)-4-methylpyrimidin-5-yl]methyl]-N-[(5R)-1,3-dimethyl-6,7-dihydro-5H-cyclopenta[c]pyridin-5-yl]pyrazole-4-carboxamide;1-[[2-(3-azabicyclo[3.1.0]hexan-3-yl)-4-methylpyrimidin-5-yl]methyl]-N-[(5R)-1,3-dimethyl-6,7-dihydro-5H-cyclopenta[c]pyridin-5-yl]triazole-4-carboxamide;1-[[2-(3-azabicyclo[3.1.0]hexan-3-yl)-4-methylpyrimidin-5-yl]methyl]-N-[(5R)-1-methyl-6,7-dihydro-5H-cyclopenta[c]pyridin-5-yl]pyrazole-4-carboxamide;1-[[2-(3-azabicyclo[3.1.0]hexan-3-yl)-4-methylpyrimidin-5-yl]methyl]-N-[(5R)-1-methyl-6,7-dihydro-5H-cyclopenta[c]pyridin-5-yl]triazole-4-carboxamide;1-[[6-(5-azaspiro[2.4]heptan-5-yl)-2-methyl-3-pyridinyl]methyl]-N-[(5R)-1-methyl-6,7-dihydro-5H-cyclopenta[c]pyridin-5-yl]pyrazole-4-carboxamide;1-[[6-[(1R,5S)-6-cyano-3-azabicyclo[3.1.0]hexan-3-yl]-2-methyl-3-pyridinyl]methyl]-N-[(5R)-1-methyl-6,7-dihydro-5H-cyclopenta[c]pyridin-5-yl]pyrazole-4-carboxamide;1-[[6-(6,6-difluoro-3-azabicyclo[3.1.0]hexan-3-yl)-2-methyl-3-pyridinyl]methyl]-N-[(5R)-1,3-dimethyl-6,7-dihydro-5H-cyclopenta[c]pyridin-5-yl]pyrazole-4-carboxamide;1-[[6-[(1R,5S)-6-(hydroxymethyl)-3-azabicyclo[3.1.0]hexan-3-yl]-2-methyl-3-pyridinyl]methyl]-N-[(5R)-1-methyl-6,7-dihydro-5H-cyclopenta[c]pyridin-5-yl]pyrazole-4-carboxamide.
What is the SMILES notation for 1-[[6-(3-azabicyclo[3.1.0]hexan-3-yl)-2-methyl-3-pyridinyl]methyl]-N-[(5R)-1,3-dimethyl-6,7-dihydro-5H-cyclopenta[c]pyridin-5-yl]-3-methylpyrazole-4-carboxamide;1-[[2-(3-azabicyclo[3.1.0]hexan-3-yl)-4-methylpyrimidin-5-yl]methyl]-N-[(5R)-1,3-dimethyl-6,7-dihydro-5H-cyclopenta[c]pyridin-5-yl]pyrazole-4-carboxamide;1-[[2-(3-azabicyclo[3.1.0]hexan-3-yl)-4-methylpyrimidin-5-yl]methyl]-N-[(5R)-1,3-dimethyl-6,7-dihydro-5H-cyclopenta[c]pyridin-5-yl]triazole-4-carboxamide;1-[[2-(3-azabicyclo[3.1.0]hexan-3-yl)-4-methylpyrimidin-5-yl]methyl]-N-[(5R)-1-methyl-6,7-dihydro-5H-cyclopenta[c]pyridin-5-yl]pyrazole-4-carboxamide;1-[[2-(3-azabicyclo[3.1.0]hexan-3-yl)-4-methylpyrimidin-5-yl]methyl]-N-[(5R)-1-methyl-6,7-dihydro-5H-cyclopenta[c]pyridin-5-yl]triazole-4-carboxamide;1-[[6-(5-azaspiro[2.4]heptan-5-yl)-2-methyl-3-pyridinyl]methyl]-N-[(5R)-1-methyl-6,7-dihydro-5H-cyclopenta[c]pyridin-5-yl]pyrazole-4-carboxamide;1-[[6-[(1R,5S)-6-cyano-3-azabicyclo[3.1.0]hexan-3-yl]-2-methyl-3-pyridinyl]methyl]-N-[(5R)-1-methyl-6,7-dihydro-5H-cyclopenta[c]pyridin-5-yl]pyrazole-4-carboxamide;1-[[6-(6,6-difluoro-3-azabicyclo[3.1.0]hexan-3-yl)-2-methyl-3-pyridinyl]methyl]-N-[(5R)-1,3-dimethyl-6,7-dihydro-5H-cyclopenta[c]pyridin-5-yl]pyrazole-4-carboxamide;1-[[6-[(1R,5S)-6-(hydroxymethyl)-3-azabicyclo[3.1.0]hexan-3-yl]-2-methyl-3-pyridinyl]methyl]-N-[(5R)-1-methyl-6,7-dihydro-5H-cyclopenta[c]pyridin-5-yl]pyrazole-4-carboxamide?
The canonical SMILES for 1-[[6-(3-azabicyclo[3.1.0]hexan-3-yl)-2-methyl-3-pyridinyl]methyl]-N-[(5R)-1,3-dimethyl-6,7-dihydro-5H-cyclopenta[c]pyridin-5-yl]-3-methylpyrazole-4-carboxamide;1-[[2-(3-azabicyclo[3.1.0]hexan-3-yl)-4-methylpyrimidin-5-yl]methyl]-N-[(5R)-1,3-dimethyl-6,7-dihydro-5H-cyclopenta[c]pyridin-5-yl]pyrazole-4-carboxamide;1-[[2-(3-azabicyclo[3.1.0]hexan-3-yl)-4-methylpyrimidin-5-yl]methyl]-N-[(5R)-1,3-dimethyl-6,7-dihydro-5H-cyclopenta[c]pyridin-5-yl]triazole-4-carboxamide;1-[[2-(3-azabicyclo[3.1.0]hexan-3-yl)-4-methylpyrimidin-5-yl]methyl]-N-[(5R)-1-methyl-6,7-dihydro-5H-cyclopenta[c]pyridin-5-yl]pyrazole-4-carboxamide;1-[[2-(3-azabicyclo[3.1.0]hexan-3-yl)-4-methylpyrimidin-5-yl]methyl]-N-[(5R)-1-methyl-6,7-dihydro-5H-cyclopenta[c]pyridin-5-yl]triazole-4-carboxamide;1-[[6-(5-azaspiro[2.4]heptan-5-yl)-2-methyl-3-pyridinyl]methyl]-N-[(5R)-1-methyl-6,7-dihydro-5H-cyclopenta[c]pyridin-5-yl]pyrazole-4-carboxamide;1-[[6-[(1R,5S)-6-cyano-3-azabicyclo[3.1.0]hexan-3-yl]-2-methyl-3-pyridinyl]methyl]-N-[(5R)-1-methyl-6,7-dihydro-5H-cyclopenta[c]pyridin-5-yl]pyrazole-4-carboxamide;1-[[6-(6,6-difluoro-3-azabicyclo[3.1.0]hexan-3-yl)-2-methyl-3-pyridinyl]methyl]-N-[(5R)-1,3-dimethyl-6,7-dihydro-5H-cyclopenta[c]pyridin-5-yl]pyrazole-4-carboxamide;1-[[6-[(1R,5S)-6-(hydroxymethyl)-3-azabicyclo[3.1.0]hexan-3-yl]-2-methyl-3-pyridinyl]methyl]-N-[(5R)-1-methyl-6,7-dihydro-5H-cyclopenta[c]pyridin-5-yl]pyrazole-4-carboxamide is Cc1cc2c(c(C)n1)CC[C@H]2NC(=O)c1cn(Cc2ccc(N3CC4CC4C3)nc2C)nc1C.Cc1cc2c(c(C)n1)CC[C@H]2NC(=O)c1cn(Cc2cnc(N3CC4CC4C3)nc2C)nn1.Cc1cc2c(c(C)n1)CC[C@H]2NC(=O)c1cnn(Cc2ccc(N3CC4C(C3)C4(F)F)nc2C)c1.Cc1cc2c(c(C)n1)CC[C@H]2NC(=O)c1cnn(Cc2cnc(N3CC4CC4C3)nc2C)c1.Cc1nc(N2CC3CC3C2)ncc1Cn1cc(C(=O)N[C@@H]2CCc3c2ccnc3C)cn1.Cc1nc(N2CC3CC3C2)ncc1Cn1cc(C(=O)N[C@@H]2CCc3c2ccnc3C)nn1.Cc1nc(N2CCC3(CC3)C2)ccc1Cn1cc(C(=O)N[C@@H]2CCc3c2ccnc3C)cn1.Cc1nc(N2C[C@@H]3C(C#N)[C@@H]3C2)ccc1Cn1cc(C(=O)N[C@@H]2CCc3c2ccnc3C)cn1.Cc1nc(N2C[C@@H]3C(CO)[C@@H]3C2)ccc1Cn1cc(C(=O)N[C@@H]2CCc3c2ccnc3C)cn1.
What is the InChIKey of 1-[[6-(3-azabicyclo[3.1.0]hexan-3-yl)-2-methyl-3-pyridinyl]methyl]-N-[(5R)-1,3-dimethyl-6,7-dihydro-5H-cyclopenta[c]pyridin-5-yl]-3-methylpyrazole-4-carboxamide;1-[[2-(3-azabicyclo[3.1.0]hexan-3-yl)-4-methylpyrimidin-5-yl]methyl]-N-[(5R)-1,3-dimethyl-6,7-dihydro-5H-cyclopenta[c]pyridin-5-yl]pyrazole-4-carboxamide;1-[[2-(3-azabicyclo[3.1.0]hexan-3-yl)-4-methylpyrimidin-5-yl]methyl]-N-[(5R)-1,3-dimethyl-6,7-dihydro-5H-cyclopenta[c]pyridin-5-yl]triazole-4-carboxamide;1-[[2-(3-azabicyclo[3.1.0]hexan-3-yl)-4-methylpyrimidin-5-yl]methyl]-N-[(5R)-1-methyl-6,7-dihydro-5H-cyclopenta[c]pyridin-5-yl]pyrazole-4-carboxamide;1-[[2-(3-azabicyclo[3.1.0]hexan-3-yl)-4-methylpyrimidin-5-yl]methyl]-N-[(5R)-1-methyl-6,7-dihydro-5H-cyclopenta[c]pyridin-5-yl]triazole-4-carboxamide;1-[[6-(5-azaspiro[2.4]heptan-5-yl)-2-methyl-3-pyridinyl]methyl]-N-[(5R)-1-methyl-6,7-dihydro-5H-cyclopenta[c]pyridin-5-yl]pyrazole-4-carboxamide;1-[[6-[(1R,5S)-6-cyano-3-azabicyclo[3.1.0]hexan-3-yl]-2-methyl-3-pyridinyl]methyl]-N-[(5R)-1-methyl-6,7-dihydro-5H-cyclopenta[c]pyridin-5-yl]pyrazole-4-carboxamide;1-[[6-(6,6-difluoro-3-azabicyclo[3.1.0]hexan-3-yl)-2-methyl-3-pyridinyl]methyl]-N-[(5R)-1,3-dimethyl-6,7-dihydro-5H-cyclopenta[c]pyridin-5-yl]pyrazole-4-carboxamide;1-[[6-[(1R,5S)-6-(hydroxymethyl)-3-azabicyclo[3.1.0]hexan-3-yl]-2-methyl-3-pyridinyl]methyl]-N-[(5R)-1-methyl-6,7-dihydro-5H-cyclopenta[c]pyridin-5-yl]pyrazole-4-carboxamide?
The InChIKey is KNKNOALVVKLGIV-SEQOBTOLSA-N. The full InChI is InChI=1S/C27H32N6O.C26H28F2N6O.C26H27N7O.C26H30N6O2.C26H30N6O.C25H29N7O.C24H28N8O.C24H27N7O.C23H26N8O/c1-15-9-23-22(17(3)28-15)6-7-25(23)30-27(34)24-14-33(31-18(24)4)13-19-5-8-26(29-16(19)2)32-11-20-10-21(20)12-32;1-14-8-20-19(16(3)30-14)5-6-23(20)32-25(35)18-9-29-34(11-18)10-17-4-7-24(31-15(17)2)33-12-21-22(13-33)26(21,27)28;1-15-17(3-6-25(30-15)32-13-22-21(9-27)23(22)14-32)11-33-12-18(10-29-33)26(34)31-24-5-4-19-16(2)28-8-7-20(19)24;1-15-17(3-6-25(29-15)31-12-21-22(13-31)23(21)14-33)10-32-11-18(9-28-32)26(34)30-24-5-4-19-16(2)27-8-7-20(19)24;1-17-19(3-6-24(29-17)31-12-10-26(16-31)8-9-26)14-32-15-20(13-28-32)25(33)30-23-5-4-21-18(2)27-11-7-22(21)23;1-14-6-22-21(16(3)28-14)4-5-23(22)30-24(33)20-9-27-32(13-20)12-19-8-26-25(29-15(19)2)31-10-17-7-18(17)11-31;1-13-6-20-19(15(3)26-13)4-5-21(20)28-23(33)22-12-32(30-29-22)11-18-8-25-24(27-14(18)2)31-9-16-7-17(16)10-31;1-14-18(8-26-24(28-14)30-10-16-7-17(16)11-30)12-31-13-19(9-27-31)23(32)29-22-4-3-20-15(2)25-6-5-21(20)22;1-13-17(8-25-23(26-13)30-9-15-7-16(15)10-30)11-31-12-21(28-29-31)22(32)27-20-4-3-18-14(2)24-6-5-19(18)20/h5,8-9,14,20-21,25H,6-7,10-13H2,1-4H3,(H,30,34);4,7-9,11,21-23H,5-6,10,12-13H2,1-3H3,(H,32,35);3,6-8,10,12,21-24H,4-5,11,13-14H2,1-2H3,(H,31,34);3,6-9,11,21-24,33H,4-5,10,12-14H2,1-2H3,(H,30,34);3,6-7,11,13,15,23H,4-5,8-10,12,14,16H2,1-2H3,(H,30,33);6,8-9,13,17-18,23H,4-5,7,10-12H2,1-3H3,(H,30,33);6,8,12,16-17,21H,4-5,7,9-11H2,1-3H3,(H,28,33);5-6,8-9,13,16-17,22H,3-4,7,10-12H2,1-2H3,(H,29,32);5-6,8,12,15-16,20H,3-4,7,9-11H2,1-2H3,(H,27,32)/t20?,21?,25-;21?,22?,23-;21?,22-,23+,24-;21-,22+,23?,24-;23-;17?,18?,23-;16?,17?,21-;16?,17?,22-;15?,16?,20-/m111111111/s1.
What are the key properties of 1-[[6-(3-azabicyclo[3.1.0]hexan-3-yl)-2-methyl-3-pyridinyl]methyl]-N-[(5R)-1,3-dimethyl-6,7-dihydro-5H-cyclopenta[c]pyridin-5-yl]-3-methylpyrazole-4-carboxamide;1-[[2-(3-azabicyclo[3.1.0]hexan-3-yl)-4-methylpyrimidin-5-yl]methyl]-N-[(5R)-1,3-dimethyl-6,7-dihydro-5H-cyclopenta[c]pyridin-5-yl]pyrazole-4-carboxamide;1-[[2-(3-azabicyclo[3.1.0]hexan-3-yl)-4-methylpyrimidin-5-yl]methyl]-N-[(5R)-1,3-dimethyl-6,7-dihydro-5H-cyclopenta[c]pyridin-5-yl]triazole-4-carboxamide;1-[[2-(3-azabicyclo[3.1.0]hexan-3-yl)-4-methylpyrimidin-5-yl]methyl]-N-[(5R)-1-methyl-6,7-dihydro-5H-cyclopenta[c]pyridin-5-yl]pyrazole-4-carboxamide;1-[[2-(3-azabicyclo[3.1.0]hexan-3-yl)-4-methylpyrimidin-5-yl]methyl]-N-[(5R)-1-methyl-6,7-dihydro-5H-cyclopenta[c]pyridin-5-yl]triazole-4-carboxamide;1-[[6-(5-azaspiro[2.4]heptan-5-yl)-2-methyl-3-pyridinyl]methyl]-N-[(5R)-1-methyl-6,7-dihydro-5H-cyclopenta[c]pyridin-5-yl]pyrazole-4-carboxamide;1-[[6-[(1R,5S)-6-cyano-3-azabicyclo[3.1.0]hexan-3-yl]-2-methyl-3-pyridinyl]methyl]-N-[(5R)-1-methyl-6,7-dihydro-5H-cyclopenta[c]pyridin-5-yl]pyrazole-4-carboxamide;1-[[6-(6,6-difluoro-3-azabicyclo[3.1.0]hexan-3-yl)-2-methyl-3-pyridinyl]methyl]-N-[(5R)-1,3-dimethyl-6,7-dihydro-5H-cyclopenta[c]pyridin-5-yl]pyrazole-4-carboxamide;1-[[6-[(1R,5S)-6-(hydroxymethyl)-3-azabicyclo[3.1.0]hexan-3-yl]-2-methyl-3-pyridinyl]methyl]-N-[(5R)-1-methyl-6,7-dihydro-5H-cyclopenta[c]pyridin-5-yl]pyrazole-4-carboxamide?
1-[[6-(3-azabicyclo[3.1.0]hexan-3-yl)-2-methyl-3-pyridinyl]methyl]-N-[(5R)-1,3-dimethyl-6,7-dihydro-5H-cyclopenta[c]pyridin-5-yl]-3-methylpyrazole-4-carboxamide;1-[[2-(3-azabicyclo[3.1.0]hexan-3-yl)-4-methylpyrimidin-5-yl]methyl]-N-[(5R)-1,3-dimethyl-6,7-dihydro-5H-cyclopenta[c]pyridin-5-yl]pyrazole-4-carboxamide;1-[[2-(3-azabicyclo[3.1.0]hexan-3-yl)-4-methylpyrimidin-5-yl]methyl]-N-[(5R)-1,3-dimethyl-6,7-dihydro-5H-cyclopenta[c]pyridin-5-yl]triazole-4-carboxamide;1-[[2-(3-azabicyclo[3.1.0]hexan-3-yl)-4-methylpyrimidin-5-yl]methyl]-N-[(5R)-1-methyl-6,7-dihydro-5H-cyclopenta[c]pyridin-5-yl]pyrazole-4-carboxamide;1-[[2-(3-azabicyclo[3.1.0]hexan-3-yl)-4-methylpyrimidin-5-yl]methyl]-N-[(5R)-1-methyl-6,7-dihydro-5H-cyclopenta[c]pyridin-5-yl]triazole-4-carboxamide;1-[[6-(5-azaspiro[2.4]heptan-5-yl)-2-methyl-3-pyridinyl]methyl]-N-[(5R)-1-methyl-6,7-dihydro-5H-cyclopenta[c]pyridin-5-yl]pyrazole-4-carboxamide;1-[[6-[(1R,5S)-6-cyano-3-azabicyclo[3.1.0]hexan-3-yl]-2-methyl-3-pyridinyl]methyl]-N-[(5R)-1-methyl-6,7-dihydro-5H-cyclopenta[c]pyridin-5-yl]pyrazole-4-carboxamide;1-[[6-(6,6-difluoro-3-azabicyclo[3.1.0]hexan-3-yl)-2-methyl-3-pyridinyl]methyl]-N-[(5R)-1,3-dimethyl-6,7-dihydro-5H-cyclopenta[c]pyridin-5-yl]pyrazole-4-carboxamide;1-[[6-[(1R,5S)-6-(hydroxymethyl)-3-azabicyclo[3.1.0]hexan-3-yl]-2-methyl-3-pyridinyl]methyl]-N-[(5R)-1-methyl-6,7-dihydro-5H-cyclopenta[c]pyridin-5-yl]pyrazole-4-carboxamide has a molecular weight of 4037.97 g/mol, XLogP of 26.56, 46 rotatable bonds, 10 hydrogen bond donors, and 62 hydrogen bond acceptors.
Where does this data come from?
All data for 1-[[6-(3-azabicyclo[3.1.0]hexan-3-yl)-2-methyl-3-pyridinyl]methyl]-N-[(5R)-1,3-dimethyl-6,7-dihydro-5H-cyclopenta[c]pyridin-5-yl]-3-methylpyrazole-4-carboxamide;1-[[2-(3-azabicyclo[3.1.0]hexan-3-yl)-4-methylpyrimidin-5-yl]methyl]-N-[(5R)-1,3-dimethyl-6,7-dihydro-5H-cyclopenta[c]pyridin-5-yl]pyrazole-4-carboxamide;1-[[2-(3-azabicyclo[3.1.0]hexan-3-yl)-4-methylpyrimidin-5-yl]methyl]-N-[(5R)-1,3-dimethyl-6,7-dihydro-5H-cyclopenta[c]pyridin-5-yl]triazole-4-carboxamide;1-[[2-(3-azabicyclo[3.1.0]hexan-3-yl)-4-methylpyrimidin-5-yl]methyl]-N-[(5R)-1-methyl-6,7-dihydro-5H-cyclopenta[c]pyridin-5-yl]pyrazole-4-carboxamide;1-[[2-(3-azabicyclo[3.1.0]hexan-3-yl)-4-methylpyrimidin-5-yl]methyl]-N-[(5R)-1-methyl-6,7-dihydro-5H-cyclopenta[c]pyridin-5-yl]triazole-4-carboxamide;1-[[6-(5-azaspiro[2.4]heptan-5-yl)-2-methyl-3-pyridinyl]methyl]-N-[(5R)-1-methyl-6,7-dihydro-5H-cyclopenta[c]pyridin-5-yl]pyrazole-4-carboxamide;1-[[6-[(1R,5S)-6-cyano-3-azabicyclo[3.1.0]hexan-3-yl]-2-methyl-3-pyridinyl]methyl]-N-[(5R)-1-methyl-6,7-dihydro-5H-cyclopenta[c]pyridin-5-yl]pyrazole-4-carboxamide;1-[[6-(6,6-difluoro-3-azabicyclo[3.1.0]hexan-3-yl)-2-methyl-3-pyridinyl]methyl]-N-[(5R)-1,3-dimethyl-6,7-dihydro-5H-cyclopenta[c]pyridin-5-yl]pyrazole-4-carboxamide;1-[[6-[(1R,5S)-6-(hydroxymethyl)-3-azabicyclo[3.1.0]hexan-3-yl]-2-methyl-3-pyridinyl]methyl]-N-[(5R)-1-methyl-6,7-dihydro-5H-cyclopenta[c]pyridin-5-yl]pyrazole-4-carboxamide is sourced from PubChem (CID 159185333), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).