N-(5-tert-butylnaphthalen-2-yl)-1H-pyrazolo[4,3-b]pyridin-3-amine;N-[5-(3,3-difluoropyrrolidin-1-yl)naphthalen-2-yl]-1H-pyrazolo[4,3-b]pyridin-3-amine;N-[5-(2-methylpiperidin-1-yl)naphthalen-2-yl]-1H-pyrazolo[4,3-b]pyridin-3-amine;N-[5-(4-methylpiperidin-1-yl)naphthalen-2-yl]-1H-pyrazolo[4,3-b]pyridin-3-amine;N-[5-(4-pyrimidin-2-ylpiperazin-1-yl)naphthalen-2-yl]-1H-pyrazolo[4,3-b]pyridin-3-amine

C108H105F2N27 — CID 159204829

IUPACN-(5-tert-butylnaphthalen-2-yl)-1H-pyrazolo[4,3-b]pyridin-3-amine;N-[5-(3,3-difluoropyrrolidin-1-yl)naphthalen-2-yl]-1H-pyrazolo[4,3-b]pyridin-3-amine;N-[5-(2-methylpiperidin-1-yl)naphthalen-2-yl]-1H-pyrazolo[4,3-b]pyridin-3-amine;N-[5-(4-methylpiperidin-1-yl)naphthalen-2-yl]-1H-pyrazolo[4,3-b]pyridin-3-amine;N-[5-(4-pyrimidin-2-ylpiperazin-1-yl)naphthalen-2-yl]-1H-pyrazolo[4,3-b]pyridin-3-amine
SMILESCC(C)(C)c1cccc2cc(Nc3n[nH]c4cccnc34)ccc12.CC1CCCCN1c1cccc2cc(Nc3n[nH]c4cccnc34)ccc12.CC1CCN(c2cccc3cc(Nc4n[nH]c5cccnc45)ccc23)CC1.FC1(F)CCN(c2cccc3cc(Nc4n[nH]c5cccnc45)ccc23)C1.c1cnc(N2CCN(c3cccc4cc(Nc5n[nH]c6cccnc56)ccc34)CC2)nc1
InChIInChI=1S/C24H22N8.2C22H23N5.C20H17F2N5.C20H20N4/c1-4-17-16-18(28-23-22-20(29-30-23)5-2-9-25-22)7-8-19(17)21(6-1)31-12-14-32(15-13-31)24-26-10-3-11-27-24;1-15-9-12-27(13-10-15)20-6-2-4-16-14-17(7-8-18(16)20)24-22-21-19(25-26-22)5-3-11-23-21;1-15-6-2-3-13-27(15)20-9-4-7-16-14-17(10-11-18(16)20)24-22-21-19(25-26-22)8-5-12-23-21;21-20(22)8-10-27(12-20)17-5-1-3-13-11-14(6-7-15(13)17)24-19-18-16(25-26-19)4-2-9-23-18;1-20(2,3)16-7-4-6-13-12-14(9-10-15(13)16)22-19-18-17(23-24-19)8-5-11-21-18/h1-11,16H,12-15H2,(H2,28,29,30);2-8,11,14-15H,9-10,12-13H2,1H3,(H2,24,25,26);4-5,7-12,14-15H,2-3,6,13H2,1H3,(H2,24,25,26);1-7,9,11H,8,10,12H2,(H2,24,25,26);4-12H,1-3H3,(H2,22,23,24)
InChIKeyKPTAAQPEIMBFOE-UHFFFAOYSA-N
MW1819.21 g/mol
LogP24.15
Rot. Bonds15

About N-(5-tert-butylnaphthalen-2-yl)-1H-pyrazolo[4,3-b]pyridin-3-amine;N-[5-(3,3-difluoropyrrolidin-1-yl)naphthalen-2-yl]-1H-pyrazolo[4,3-b]pyridin-3-amine;N-[5-(2-methylpiperidin-1-yl)naphthalen-2-yl]-1H-pyrazolo[4,3-b]pyridin-3-amine;N-[5-(4-methylpiperidin-1-yl)naphthalen-2-yl]-1H-pyrazolo[4,3-b]pyridin-3-amine;N-[5-(4-pyrimidin-2-ylpiperazin-1-yl)naphthalen-2-yl]-1H-pyrazolo[4,3-b]pyridin-3-amine

N-(5-tert-butylnaphthalen-2-yl)-1H-pyrazolo[4,3-b]pyridin-3-amine;N-[5-(3,3-difluoropyrrolidin-1-yl)naphthalen-2-yl]-1H-pyrazolo[4,3-b]pyridin-3-amine;N-[5-(2-methylpiperidin-1-yl)naphthalen-2-yl]-1H-pyrazolo[4,3-b]pyridin-3-amine;N-[5-(4-methylpiperidin-1-yl)naphthalen-2-yl]-1H-pyrazolo[4,3-b]pyridin-3-amine;N-[5-(4-pyrimidin-2-ylpiperazin-1-yl)naphthalen-2-yl]-1H-pyrazolo[4,3-b]pyridin-3-amine (PubChem CID 159204829) has the molecular formula C108H105F2N27 and a molecular weight of 1819.21 g/mol. Its IUPAC name is N-(5-tert-butylnaphthalen-2-yl)-1H-pyrazolo[4,3-b]pyridin-3-amine;N-[5-(3,3-difluoropyrrolidin-1-yl)naphthalen-2-yl]-1H-pyrazolo[4,3-b]pyridin-3-amine;N-[5-(2-methylpiperidin-1-yl)naphthalen-2-yl]-1H-pyrazolo[4,3-b]pyridin-3-amine;N-[5-(4-methylpiperidin-1-yl)naphthalen-2-yl]-1H-pyrazolo[4,3-b]pyridin-3-amine;N-[5-(4-pyrimidin-2-ylpiperazin-1-yl)naphthalen-2-yl]-1H-pyrazolo[4,3-b]pyridin-3-amine.

Molecular Properties

Compound NameN-(5-tert-butylnaphthalen-2-yl)-1H-pyrazolo[4,3-b]pyridin-3-amine;N-[5-(3,3-difluoropyrrolidin-1-yl)naphthalen-2-yl]-1H-pyrazolo[4,3-b]pyridin-3-amine;N-[5-(2-methylpiperidin-1-yl)naphthalen-2-yl]-1H-pyrazolo[4,3-b]pyridin-3-amine;N-[5-(4-methylpiperidin-1-yl)naphthalen-2-yl]-1H-pyrazolo[4,3-b]pyridin-3-amine;N-[5-(4-pyrimidin-2-ylpiperazin-1-yl)naphthalen-2-yl]-1H-pyrazolo[4,3-b]pyridin-3-amine
PubChem CID159204829
Molecular FormulaC108H105F2N27
Molecular Weight1819.21 g/mol
Exact Mass1817.90
IUPAC NameN-(5-tert-butylnaphthalen-2-yl)-1H-pyrazolo[4,3-b]pyridin-3-amine;N-[5-(3,3-difluoropyrrolidin-1-yl)naphthalen-2-yl]-1H-pyrazolo[4,3-b]pyridin-3-amine;N-[5-(2-methylpiperidin-1-yl)naphthalen-2-yl]-1H-pyrazolo[4,3-b]pyridin-3-amine;N-[5-(4-methylpiperidin-1-yl)naphthalen-2-yl]-1H-pyrazolo[4,3-b]pyridin-3-amine;N-[5-(4-pyrimidin-2-ylpiperazin-1-yl)naphthalen-2-yl]-1H-pyrazolo[4,3-b]pyridin-3-amine
SMILESCC(C)(C)c1cccc2cc(Nc3n[nH]c4cccnc34)ccc12.CC1CCCCN1c1cccc2cc(Nc3n[nH]c4cccnc34)ccc12.CC1CCN(c2cccc3cc(Nc4n[nH]c5cccnc45)ccc23)CC1.FC1(F)CCN(c2cccc3cc(Nc4n[nH]c5cccnc45)ccc23)C1.c1cnc(N2CCN(c3cccc4cc(Nc5n[nH]c6cccnc56)ccc34)CC2)nc1
InChIInChI=1S/C24H22N8.2C22H23N5.C20H17F2N5.C20H20N4/c1-4-17-16-18(28-23-22-20(29-30-23)5-2-9-25-22)7-8-19(17)21(6-1)31-12-14-32(15-13-31)24-26-10-3-11-27-24;1-15-9-12-27(13-10-15)20-6-2-4-16-14-17(7-8-18(16)20)24-22-21-19(25-26-22)5-3-11-23-21;1-15-6-2-3-13-27(15)20-9-4-7-16-14-17(10-11-18(16)20)24-22-21-19(25-26-22)8-5-12-23-21;21-20(22)8-10-27(12-20)17-5-1-3-13-11-14(6-7-15(13)17)24-19-18-16(25-26-19)4-2-9-23-18;1-20(2,3)16-7-4-6-13-12-14(9-10-15(13)16)22-19-18-17(23-24-19)8-5-11-21-18/h1-11,16H,12-15H2,(H2,28,29,30);2-8,11,14-15H,9-10,12-13H2,1H3,(H2,24,25,26);4-5,7-12,14-15H,2-3,6,13H2,1H3,(H2,24,25,26);1-7,9,11H,8,10,12H2,(H2,24,25,26);4-12H,1-3H3,(H2,22,23,24)
InChIKeyKPTAAQPEIMBFOE-UHFFFAOYSA-N
XLogP24.15
TPSA309.98 Ų
H-Bond Donors10
H-Bond Acceptors22
Rotatable Bonds15
Heavy Atoms137
Complexity—

Lipinski Rule of Five

4 violations

RuleValue
MW ≤ 5001819.21
LogP ≤ 524.15
H-Bond Donors ≤ 510
H-Bond Acceptors ≤ 1022

Analyze N-(5-tert-butylnaphthalen-2-yl)-1H-pyrazolo[4,3-b]pyridin-3-amine;N-[5-(3,3-difluoropyrrolidin-1-yl)naphthalen-2-yl]-1H-pyrazolo[4,3-b]pyridin-3-amine;N-[5-(2-methylpiperidin-1-yl)naphthalen-2-yl]-1H-pyrazolo[4,3-b]pyridin-3-amine;N-[5-(4-methylpiperidin-1-yl)naphthalen-2-yl]-1H-pyrazolo[4,3-b]pyridin-3-amine;N-[5-(4-pyrimidin-2-ylpiperazin-1-yl)naphthalen-2-yl]-1H-pyrazolo[4,3-b]pyridin-3-amine with MolForge

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Related Compounds

7-(2,6-difluoro-4-((1S,4S)-5-methyl-2,5-diazabicyclo[2.2.1]heptan-2-yl)phenyl)-3-(1H-indazol-4-yl)-2-(pyridin-4-yl)pyrazolo[1,5-a]pyrimidine
CID 44187005
3-(1h-Indazol-4-yl)-7-(2-methyl-4-((1s,4s)-5-methyl-2,5-diazabicyclo[2.2.1]heptan-2-yl)phenyl)-2-(pyridin-4-yl)pyrazolo[1,5-a]pyrimidine
CID 49836427
7-(2-Fluoro-4-((1s,4s)-5-methyl-2,5-diazabicyclo[2.2.1]heptan-2-yl)phenyl)-3-(1h-indazol-4-yl)-2-(pyridin-4-yl)pyrazolo[1,5-a]pyrimidine
CID 49836539
3-(1H-indazol-4-yl)-7-(4-((1S,4S)-5-methyl-2,5-diazabicyclo[2.2.1]heptan-2-yl)naphthalen-1-yl)-2-(pyridin-4-yl)pyrazolo[1,5-a]pyrimidine
CID 49836649
7-(2,3-difluoro-4-((1S,4S)-5-methyl-2,5-diazabicyclo[2.2.1]heptan-2-yl)phenyl)-3-(1H-indazol-4-yl)-2-(pyridin-4-yl)pyrazolo[1,5-a]pyrimidine
CID 49836748
7-(2,5-difluoro-4-((1S,4S)-5-methyl-2,5-diazabicyclo[2.2.1]heptan-2-yl)phenyl)-3-(1H-indazol-4-yl)-2-(pyridin-4-yl)pyrazolo[1,5-a]pyrimidine
CID 49836749
3-(1H-indazol-4-yl)-2-(pyridin-4-yl)-7-(2,3,5,6-tetrafluoro-4-((1S,4S)-5-methyl-2,5-diazabicyclo[2.2.1]heptan-2-yl)phenyl)pyrazolo[1,5-a]pyrimidine
CID 49836854
3-(7-fluoro-1H-indazol-4-yl)-7-(4-((1S,4S)-5-methyl-2,5-diazabicyclo[2.2.1]heptan-2-yl)phenyl)-2-(pyridin-4-yl)pyrazolo[1,5-a]pyrimidine
CID 49836857
3-(7-fluoro-1H-indazol-4-yl)-7-[2-methyl-4-[(1S,4S)-5-methyl-2,5-diazabicyclo[2.2.1]heptan-2-yl]phenyl]-2-pyridin-4-ylpyrazolo[1,5-a]pyrimidine
CID 49836964
3-(7-fluoro-1H-indazol-4-yl)-7-[2-fluoro-4-[(1S,4S)-5-methyl-2,5-diazabicyclo[2.2.1]heptan-2-yl]phenyl]-2-pyridin-4-ylpyrazolo[1,5-a]pyrimidine
CID 49836965
7-(2,6-Difluoro-4-((1s,4s)-5-methyl-2,5-diazabicyclo[2.2.1]heptan-2-yl)phenyl)-3-(7-fluoro-1h-indazol-4-yl)-2-(pyridin-4-yl)pyrazolo[1,5-a]pyrimidine
CID 49836966
(1S,4S)-2-(4-(3-(1H-indazol-4-yl)-2-(pyridin-4-yl)pyrazolo[1,5-a]pyrimidin-7-yl)phenyl)-5-methyl-2,5-diazabicyclo[2.2.2]octane
CID 49836968

Frequently Asked Questions

What is the IUPAC name of N-(5-tert-butylnaphthalen-2-yl)-1H-pyrazolo[4,3-b]pyridin-3-amine;N-[5-(3,3-difluoropyrrolidin-1-yl)naphthalen-2-yl]-1H-pyrazolo[4,3-b]pyridin-3-amine;N-[5-(2-methylpiperidin-1-yl)naphthalen-2-yl]-1H-pyrazolo[4,3-b]pyridin-3-amine;N-[5-(4-methylpiperidin-1-yl)naphthalen-2-yl]-1H-pyrazolo[4,3-b]pyridin-3-amine;N-[5-(4-pyrimidin-2-ylpiperazin-1-yl)naphthalen-2-yl]-1H-pyrazolo[4,3-b]pyridin-3-amine?
The IUPAC name of N-(5-tert-butylnaphthalen-2-yl)-1H-pyrazolo[4,3-b]pyridin-3-amine;N-[5-(3,3-difluoropyrrolidin-1-yl)naphthalen-2-yl]-1H-pyrazolo[4,3-b]pyridin-3-amine;N-[5-(2-methylpiperidin-1-yl)naphthalen-2-yl]-1H-pyrazolo[4,3-b]pyridin-3-amine;N-[5-(4-methylpiperidin-1-yl)naphthalen-2-yl]-1H-pyrazolo[4,3-b]pyridin-3-amine;N-[5-(4-pyrimidin-2-ylpiperazin-1-yl)naphthalen-2-yl]-1H-pyrazolo[4,3-b]pyridin-3-amine (CID 159204829) is N-(5-tert-butylnaphthalen-2-yl)-1H-pyrazolo[4,3-b]pyridin-3-amine;N-[5-(3,3-difluoropyrrolidin-1-yl)naphthalen-2-yl]-1H-pyrazolo[4,3-b]pyridin-3-amine;N-[5-(2-methylpiperidin-1-yl)naphthalen-2-yl]-1H-pyrazolo[4,3-b]pyridin-3-amine;N-[5-(4-methylpiperidin-1-yl)naphthalen-2-yl]-1H-pyrazolo[4,3-b]pyridin-3-amine;N-[5-(4-pyrimidin-2-ylpiperazin-1-yl)naphthalen-2-yl]-1H-pyrazolo[4,3-b]pyridin-3-amine.
What is the SMILES notation for N-(5-tert-butylnaphthalen-2-yl)-1H-pyrazolo[4,3-b]pyridin-3-amine;N-[5-(3,3-difluoropyrrolidin-1-yl)naphthalen-2-yl]-1H-pyrazolo[4,3-b]pyridin-3-amine;N-[5-(2-methylpiperidin-1-yl)naphthalen-2-yl]-1H-pyrazolo[4,3-b]pyridin-3-amine;N-[5-(4-methylpiperidin-1-yl)naphthalen-2-yl]-1H-pyrazolo[4,3-b]pyridin-3-amine;N-[5-(4-pyrimidin-2-ylpiperazin-1-yl)naphthalen-2-yl]-1H-pyrazolo[4,3-b]pyridin-3-amine?
The canonical SMILES for N-(5-tert-butylnaphthalen-2-yl)-1H-pyrazolo[4,3-b]pyridin-3-amine;N-[5-(3,3-difluoropyrrolidin-1-yl)naphthalen-2-yl]-1H-pyrazolo[4,3-b]pyridin-3-amine;N-[5-(2-methylpiperidin-1-yl)naphthalen-2-yl]-1H-pyrazolo[4,3-b]pyridin-3-amine;N-[5-(4-methylpiperidin-1-yl)naphthalen-2-yl]-1H-pyrazolo[4,3-b]pyridin-3-amine;N-[5-(4-pyrimidin-2-ylpiperazin-1-yl)naphthalen-2-yl]-1H-pyrazolo[4,3-b]pyridin-3-amine is CC(C)(C)c1cccc2cc(Nc3n[nH]c4cccnc34)ccc12.CC1CCCCN1c1cccc2cc(Nc3n[nH]c4cccnc34)ccc12.CC1CCN(c2cccc3cc(Nc4n[nH]c5cccnc45)ccc23)CC1.FC1(F)CCN(c2cccc3cc(Nc4n[nH]c5cccnc45)ccc23)C1.c1cnc(N2CCN(c3cccc4cc(Nc5n[nH]c6cccnc56)ccc34)CC2)nc1.
What is the InChIKey of N-(5-tert-butylnaphthalen-2-yl)-1H-pyrazolo[4,3-b]pyridin-3-amine;N-[5-(3,3-difluoropyrrolidin-1-yl)naphthalen-2-yl]-1H-pyrazolo[4,3-b]pyridin-3-amine;N-[5-(2-methylpiperidin-1-yl)naphthalen-2-yl]-1H-pyrazolo[4,3-b]pyridin-3-amine;N-[5-(4-methylpiperidin-1-yl)naphthalen-2-yl]-1H-pyrazolo[4,3-b]pyridin-3-amine;N-[5-(4-pyrimidin-2-ylpiperazin-1-yl)naphthalen-2-yl]-1H-pyrazolo[4,3-b]pyridin-3-amine?
The InChIKey is KPTAAQPEIMBFOE-UHFFFAOYSA-N. The full InChI is InChI=1S/C24H22N8.2C22H23N5.C20H17F2N5.C20H20N4/c1-4-17-16-18(28-23-22-20(29-30-23)5-2-9-25-22)7-8-19(17)21(6-1)31-12-14-32(15-13-31)24-26-10-3-11-27-24;1-15-9-12-27(13-10-15)20-6-2-4-16-14-17(7-8-18(16)20)24-22-21-19(25-26-22)5-3-11-23-21;1-15-6-2-3-13-27(15)20-9-4-7-16-14-17(10-11-18(16)20)24-22-21-19(25-26-22)8-5-12-23-21;21-20(22)8-10-27(12-20)17-5-1-3-13-11-14(6-7-15(13)17)24-19-18-16(25-26-19)4-2-9-23-18;1-20(2,3)16-7-4-6-13-12-14(9-10-15(13)16)22-19-18-17(23-24-19)8-5-11-21-18/h1-11,16H,12-15H2,(H2,28,29,30);2-8,11,14-15H,9-10,12-13H2,1H3,(H2,24,25,26);4-5,7-12,14-15H,2-3,6,13H2,1H3,(H2,24,25,26);1-7,9,11H,8,10,12H2,(H2,24,25,26);4-12H,1-3H3,(H2,22,23,24).
What are the key properties of N-(5-tert-butylnaphthalen-2-yl)-1H-pyrazolo[4,3-b]pyridin-3-amine;N-[5-(3,3-difluoropyrrolidin-1-yl)naphthalen-2-yl]-1H-pyrazolo[4,3-b]pyridin-3-amine;N-[5-(2-methylpiperidin-1-yl)naphthalen-2-yl]-1H-pyrazolo[4,3-b]pyridin-3-amine;N-[5-(4-methylpiperidin-1-yl)naphthalen-2-yl]-1H-pyrazolo[4,3-b]pyridin-3-amine;N-[5-(4-pyrimidin-2-ylpiperazin-1-yl)naphthalen-2-yl]-1H-pyrazolo[4,3-b]pyridin-3-amine?
N-(5-tert-butylnaphthalen-2-yl)-1H-pyrazolo[4,3-b]pyridin-3-amine;N-[5-(3,3-difluoropyrrolidin-1-yl)naphthalen-2-yl]-1H-pyrazolo[4,3-b]pyridin-3-amine;N-[5-(2-methylpiperidin-1-yl)naphthalen-2-yl]-1H-pyrazolo[4,3-b]pyridin-3-amine;N-[5-(4-methylpiperidin-1-yl)naphthalen-2-yl]-1H-pyrazolo[4,3-b]pyridin-3-amine;N-[5-(4-pyrimidin-2-ylpiperazin-1-yl)naphthalen-2-yl]-1H-pyrazolo[4,3-b]pyridin-3-amine has a molecular weight of 1819.21 g/mol, XLogP of 24.15, 15 rotatable bonds, 10 hydrogen bond donors, and 22 hydrogen bond acceptors.
Where does this data come from?
All data for N-(5-tert-butylnaphthalen-2-yl)-1H-pyrazolo[4,3-b]pyridin-3-amine;N-[5-(3,3-difluoropyrrolidin-1-yl)naphthalen-2-yl]-1H-pyrazolo[4,3-b]pyridin-3-amine;N-[5-(2-methylpiperidin-1-yl)naphthalen-2-yl]-1H-pyrazolo[4,3-b]pyridin-3-amine;N-[5-(4-methylpiperidin-1-yl)naphthalen-2-yl]-1H-pyrazolo[4,3-b]pyridin-3-amine;N-[5-(4-pyrimidin-2-ylpiperazin-1-yl)naphthalen-2-yl]-1H-pyrazolo[4,3-b]pyridin-3-amine is sourced from PubChem (CID 159204829), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).