5-(1,3-benzothiazol-6-yl)-6-(3-methylpyrazol-1-yl)pyrazin-2-amine;5-(7-chloro-1H-indazol-5-yl)-6-phenylpyrazin-2-amine;5-(1H-indazol-5-yl)-6-(3-methylpyrazol-1-yl)pyrazin-2-amine;6-(1-methylpyrazol-3-yl)-5-quinolin-6-ylpyrazin-2-amine;6-(2-methyl-1,3-thiazol-5-yl)-5-quinolin-6-ylpyrazin-2-amine

C81H64ClN29S2 — CID 159218172

IUPAC5-(1,3-benzothiazol-6-yl)-6-(3-methylpyrazol-1-yl)pyrazin-2-amine;5-(7-chloro-1H-indazol-5-yl)-6-phenylpyrazin-2-amine;5-(1H-indazol-5-yl)-6-(3-methylpyrazol-1-yl)pyrazin-2-amine;6-(1-methylpyrazol-3-yl)-5-quinolin-6-ylpyrazin-2-amine;6-(2-methyl-1,3-thiazol-5-yl)-5-quinolin-6-ylpyrazin-2-amine
SMILESCc1ccn(-c2nc(N)cnc2-c2ccc3[nH]ncc3c2)n1.Cc1ccn(-c2nc(N)cnc2-c2ccc3ncsc3c2)n1.Cc1ncc(-c2nc(N)cnc2-c2ccc3ncccc3c2)s1.Cn1ccc(-c2nc(N)cnc2-c2ccc3ncccc3c2)n1.Nc1cnc(-c2cc(Cl)c3[nH]ncc3c2)c(-c2ccccc2)n1
InChIInChI=1S/C17H12ClN5.C17H14N6.C17H13N5S.C15H13N7.C15H12N6S/c18-13-7-11(6-12-8-21-23-15(12)13)16-17(22-14(19)9-20-16)10-4-2-1-3-5-10;1-23-8-6-14(22-23)17-16(20-10-15(18)21-17)12-4-5-13-11(9-12)3-2-7-19-13;1-10-20-8-14(23-10)17-16(21-9-15(18)22-17)12-4-5-13-11(7-12)3-2-6-19-13;1-9-4-5-22(21-9)15-14(17-8-13(16)19-15)10-2-3-12-11(6-10)7-18-20-12;1-9-4-5-21(20-9)15-14(17-7-13(16)19-15)10-2-3-11-12(6-10)22-8-18-11/h1-9H,(H2,19,22)(H,21,23);2-10H,1H3,(H2,18,21);2-9H,1H3,(H2,18,22);2-8H,1H3,(H2,16,19)(H,18,20);2-8H,1H3,(H2,16,19)
InChIKeyKRIONTFWCDFTCO-UHFFFAOYSA-N
MW1543.19 g/mol
LogP15.23
Rot. Bonds10

About 5-(1,3-benzothiazol-6-yl)-6-(3-methylpyrazol-1-yl)pyrazin-2-amine;5-(7-chloro-1H-indazol-5-yl)-6-phenylpyrazin-2-amine;5-(1H-indazol-5-yl)-6-(3-methylpyrazol-1-yl)pyrazin-2-amine;6-(1-methylpyrazol-3-yl)-5-quinolin-6-ylpyrazin-2-amine;6-(2-methyl-1,3-thiazol-5-yl)-5-quinolin-6-ylpyrazin-2-amine

5-(1,3-benzothiazol-6-yl)-6-(3-methylpyrazol-1-yl)pyrazin-2-amine;5-(7-chloro-1H-indazol-5-yl)-6-phenylpyrazin-2-amine;5-(1H-indazol-5-yl)-6-(3-methylpyrazol-1-yl)pyrazin-2-amine;6-(1-methylpyrazol-3-yl)-5-quinolin-6-ylpyrazin-2-amine;6-(2-methyl-1,3-thiazol-5-yl)-5-quinolin-6-ylpyrazin-2-amine (PubChem CID 159218172) has the molecular formula C81H64ClN29S2 and a molecular weight of 1543.19 g/mol. Its IUPAC name is 5-(1,3-benzothiazol-6-yl)-6-(3-methylpyrazol-1-yl)pyrazin-2-amine;5-(7-chloro-1H-indazol-5-yl)-6-phenylpyrazin-2-amine;5-(1H-indazol-5-yl)-6-(3-methylpyrazol-1-yl)pyrazin-2-amine;6-(1-methylpyrazol-3-yl)-5-quinolin-6-ylpyrazin-2-amine;6-(2-methyl-1,3-thiazol-5-yl)-5-quinolin-6-ylpyrazin-2-amine.

Molecular Properties

Compound Name5-(1,3-benzothiazol-6-yl)-6-(3-methylpyrazol-1-yl)pyrazin-2-amine;5-(7-chloro-1H-indazol-5-yl)-6-phenylpyrazin-2-amine;5-(1H-indazol-5-yl)-6-(3-methylpyrazol-1-yl)pyrazin-2-amine;6-(1-methylpyrazol-3-yl)-5-quinolin-6-ylpyrazin-2-amine;6-(2-methyl-1,3-thiazol-5-yl)-5-quinolin-6-ylpyrazin-2-amine
PubChem CID159218172
Molecular FormulaC81H64ClN29S2
Molecular Weight1543.19 g/mol
Exact Mass1541.50
IUPAC Name5-(1,3-benzothiazol-6-yl)-6-(3-methylpyrazol-1-yl)pyrazin-2-amine;5-(7-chloro-1H-indazol-5-yl)-6-phenylpyrazin-2-amine;5-(1H-indazol-5-yl)-6-(3-methylpyrazol-1-yl)pyrazin-2-amine;6-(1-methylpyrazol-3-yl)-5-quinolin-6-ylpyrazin-2-amine;6-(2-methyl-1,3-thiazol-5-yl)-5-quinolin-6-ylpyrazin-2-amine
SMILESCc1ccn(-c2nc(N)cnc2-c2ccc3[nH]ncc3c2)n1.Cc1ccn(-c2nc(N)cnc2-c2ccc3ncsc3c2)n1.Cc1ncc(-c2nc(N)cnc2-c2ccc3ncccc3c2)s1.Cn1ccc(-c2nc(N)cnc2-c2ccc3ncccc3c2)n1.Nc1cnc(-c2cc(Cl)c3[nH]ncc3c2)c(-c2ccccc2)n1
InChIInChI=1S/C17H12ClN5.C17H14N6.C17H13N5S.C15H13N7.C15H12N6S/c18-13-7-11(6-12-8-21-23-15(12)13)16-17(22-14(19)9-20-16)10-4-2-1-3-5-10;1-23-8-6-14(22-23)17-16(20-10-15(18)21-17)12-4-5-13-11(9-12)3-2-7-19-13;1-10-20-8-14(23-10)17-16(21-9-15(18)22-17)12-4-5-13-11(7-12)3-2-6-19-13;1-9-4-5-22(21-9)15-14(17-8-13(16)19-15)10-2-3-12-11(6-10)7-18-20-12;1-9-4-5-21(20-9)15-14(17-7-13(16)19-15)10-2-3-11-12(6-10)22-8-18-11/h1-9H,(H2,19,22)(H,21,23);2-10H,1H3,(H2,18,21);2-9H,1H3,(H2,18,22);2-8H,1H3,(H2,16,19)(H,18,20);2-8H,1H3,(H2,16,19)
InChIKeyKRIONTFWCDFTCO-UHFFFAOYSA-N
XLogP15.23
TPSA421.38 Ų
H-Bond Donors7
H-Bond Acceptors29
Rotatable Bonds10
Heavy Atoms113
Complexity—

Lipinski Rule of Five

4 violations

RuleValue
MW ≤ 5001543.19
LogP ≤ 515.23
H-Bond Donors ≤ 57
H-Bond Acceptors ≤ 1029

Analyze 5-(1,3-benzothiazol-6-yl)-6-(3-methylpyrazol-1-yl)pyrazin-2-amine;5-(7-chloro-1H-indazol-5-yl)-6-phenylpyrazin-2-amine;5-(1H-indazol-5-yl)-6-(3-methylpyrazol-1-yl)pyrazin-2-amine;6-(1-methylpyrazol-3-yl)-5-quinolin-6-ylpyrazin-2-amine;6-(2-methyl-1,3-thiazol-5-yl)-5-quinolin-6-ylpyrazin-2-amine with MolForge

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Launch Full Analysis

Related Compounds

6-[1-[[6-[5-Amino-3-[3-(trifluoromethyl)pyrazol-1-yl]pyrazin-2-yl]-8-chloroquinolin-3-yl]methyl]pyrazol-3-yl]-5-(4-chloro-1,3-benzothiazol-6-yl)pyrazin-2-amine
CID 156450002
4-[[3-amino-6-(7-chloro-1H-indazol-5-yl)-5-phenylpyrazin-2-yl]sulfanylmethyl]benzonitrile;5-(7-chloro-1H-indazol-5-yl)-3-[(4-fluorophenyl)methylsulfanyl]-6-phenylpyrazin-2-amine;5-(7-chloro-1H-indazol-5-yl)-3-[(1-methylpiperidin-4-yl)methylsulfanyl]-6-phenylpyrazin-2-amine;5-(7-chloro-1H-indazol-5-yl)-6-phenyl-3-(pyridin-3-ylmethylsulfanyl)pyrazin-2-amine;5-(7-chloro-1H-indazol-5-yl)-6-phenyl-3-[2-[3-(trifluoromethyl)pyrrol-1-yl]ethylsulfanyl]pyrazin-2-amine
CID 158654319
6-[[6-(1-benzothiophen-2-yl)-[1,2,4]triazolo[4,3-b]pyridazin-3-yl]methyl]quinoline;6-[[6-(5-chlorothiophen-2-yl)-[1,2,4]triazolo[4,3-b]pyridazin-3-yl]methyl]quinoline;6-[difluoro-[6-(2-methyl-4-pyridinyl)-[1,2,4]triazolo[4,3-b]pyridazin-3-yl]methyl]quinoline;1-hydroxy-6-[[6-(1H-pyrazol-4-yl)-[1,2,4]triazolo[4,3-b]pyridazin-3-yl]methyl]quinolin-1-ium;6-[[6-(2-methyl-4-pyridinyl)-[1,2,4]triazolo[4,3-b]pyridazin-3-yl]methyl]quinoline;6-[[6-(5-methylthiophen-2-yl)-[1,2,4]triazolo[4,3-b]pyridazin-3-yl]methyl]quinoline
CID 160033309
8-chloro-6-methylimidazo[1,2-a]pyridine;7-chloro-5-methyl-1H-indazole;8-chloro-6-methylquinoline;3,5-dimethyl-2H-indazole;6,8-dimethylquinoline;2,4-dimethyl-6-(trifluoromethyl)pyridine;6-methyl-1,3-benzothiazole;6-methylcinnoline;6-methylimidazo[1,2-a]pyridine;5-methyl-1H-indazole;6-methylisoquinoline;6-methylquinolin-2-amine;bis(6-methylquinoline);6-methylquinoxaline;6-methyl-1,2,3,4-tetrahydroquinoline;6-methyl-[1,2,4]triazolo[1,5-a]pyridine;6-methyl-[1,2,4]triazolo[4,3-a]pyridine;7-methyl-[1,2,4]triazolo[1,5-a]pyridine;tris(2,4,6-trimethylpyridine)
CID 161014562
3-(4,4-dimethylpiperazin-4-ium-1-yl)-1-methyl-5-propan-2-ylindazole;1,3-dimethyl-5-propan-2-ylpyrazolo[4,3-d]pyrimidine;1,3-dimethyl-5-(4-propan-2-yl-2-pyridinyl)pyrazolo[4,3-d]pyrimidine;1-methyl-5-[(2S)-1-methyl-4-propan-2-ylpiperazin-2-yl]indazole;1-methyl-5-[(2R)-1-methyl-4-propan-2-ylpiperazin-2-yl]indazole;1-methyl-5-(2-methyl-5-propan-2-yl-3-pyridinyl)pyrazolo[4,5-b]pyridine;1-methyl-5-propan-2-yl-3-[4-(1,1,1-trifluoropropan-2-yl)piperazin-1-yl]indazole;2-propan-2-yl-5-(4-propan-2-ylpiperazin-1-yl)-1,3-thiazole;5-propan-2-yl-2-(4-propan-2-ylpiperazin-1-yl)-1,3-thiazole;6-(4-propan-2-ylpyrimidin-2-yl)quinolin-2-amine
CID 161533387
6-[2-(3-chlorophenyl)-6,7-dihydro-5H-pyrrolo[1,2-a]imidazol-3-yl]-1,3-benzothiazole;6-[2-(3-chlorophenyl)-6,7-dihydro-5H-pyrrolo[1,2-a]imidazol-3-yl]-1H-indazole;6-[2-(3-chlorophenyl)-6,7-dihydro-5H-pyrrolo[1,2-a]imidazol-3-yl]quinoxaline
CID 121350314
tris(6-propan-2-yl-1H-benzimidazole);5-propan-2-yl-1,3-benzothiazole;5-propan-2-yl-1H-indazole;bis(6-propan-2-yl-1H-indazole);5-propan-2-yl-1H-isoindole;6-propan-2-ylisoquinoline;7-propan-2-ylisoquinoline;2-propan-2-ylquinazoline;6-propan-2-ylquinazoline;7-propan-2-ylquinazoline;2-propan-2-ylquinoline;6-propan-2-ylquinoline;7-propan-2-ylquinoline
CID 157062614
4-Fluoro-6-(2-methylimidazo[1,2-b]pyridazin-6-yl)-2-piperidin-4-yl-1,3-benzothiazole;4-fluoro-6-(2-methylimidazo[1,2-b]pyridazin-6-yl)-2-(1,2,3,6-tetrahydropyridin-4-yl)-1,3-benzothiazole;2-(2-methylindazol-5-yl)-6-piperidin-4-yl-[1,3]thiazolo[4,5-b]pyridine
CID 157373145
6-[5-Amino-3-(4-fluorophenyl)pyrazin-2-yl]-4-chloro-1,3-benzothiazol-2-amine;3-amino-5-(3-methylpyrrol-1-yl)-6-quinolin-6-ylpyrazine-2-carbonitrile;5-(4-chloro-2-propan-2-yl-1,3-benzothiazol-6-yl)-6-(4-fluorophenyl)pyrazin-2-amine;5-(4-chloro-2-propan-2-yl-1,3-benzothiazol-6-yl)-6-(1-methylpyrazol-3-yl)pyrazin-2-amine;6-(3-methylpyrrol-1-yl)-5-quinolin-6-ylpyrazin-2-amine
CID 157543386
1,3-Dimethyl-5-propan-2-ylpyrazolo[4,3-d]pyrimidine;1,3-dimethyl-5-(4-propan-2-yl-2-pyridinyl)pyrazolo[4,3-d]pyrimidine;1-methyl-5-(2-methyl-5-propan-2-yl-3-pyridinyl)pyrazolo[4,5-b]pyridine;2-propan-2-yl-5-(4-propan-2-ylpiperazin-1-yl)-1,3-thiazole;4-propan-2-yl-2-(4-propan-2-ylpiperazin-1-yl)-1,3-thiazole;5-propan-2-yl-2-(4-propan-2-ylpiperazin-1-yl)-1,3-thiazole;6-(4-propan-2-ylpyrimidin-2-yl)quinolin-2-amine
CID 157563028
6-tert-butyl-1H-benzimidazole;6-tert-butyl-1,3-benzothiazole;6-tert-butylimidazo[1,2-a]pyridine;2-tert-butyl-1,5-naphthyridine;3-tert-butyl-1,8-naphthyridine;6-tert-butyl-1,7-naphthyridine;3-tert-butyl-2H-pyrazolo[3,4-b]pyridine;6-tert-butylpyrido[2,3-d]pyrimidine;6-tert-butylpyrido[3,2-d]pyrimidine;6-tert-butylpyrido[3,4-d]pyrimidine;2-tert-butyl-1H-pyrrolo[2,3-b]pyridine;2-tert-butyl-1H-pyrrolo[3,2-b]pyridine;3-tert-butyl-1H-pyrrolo[2,3-b]pyridine;5-tert-butyl-3H-pyrrolo[3,2-b]pyridine;6-tert-butylquinoline;5-tert-butyl-[1,3]thiazolo[5,4-b]pyridine;6-tert-butyl-[1,3]thiazolo[4,5-b]pyridine;2-tert-butyl-[1,3]thiazolo[4,5-c]pyridine;6-tert-butyl-[1,3]thiazolo[4,5-c]pyridine;2-tert-butylthieno[3,2-b]pyridine;3-tert-butylthieno[2,3-b]pyridine;2-tert-butylthieno[3,2-c]pyridine
CID 157584694
N-[(2-chlorophenyl)methyl]-3-methyl-2H-pyrazolo[4,3-c]pyridin-4-amine;N-[(3-chlorophenyl)methyl]-3-methyl-2H-pyrazolo[4,3-c]pyridin-4-amine;N-[(3-fluorophenyl)methyl]-3-methyl-2H-pyrazolo[4,3-c]pyridin-4-amine;N-[(4-fluorophenyl)methyl]-3-methyl-2H-pyrazolo[4,3-c]pyridin-4-amine;N-(4-fluorophenyl)-3-methyl-2H-pyrazolo[4,3-c]pyridin-4-amine;3-methyl-4-[(3-methylphenyl)methyl]-2H-pyrazolo[4,3-c]pyridine;3-methyl-N-(2-methylphenyl)-2H-pyrazolo[4,3-c]pyridin-4-amine;3-methyl-N-(4-methylphenyl)-2H-pyrazolo[4,3-c]pyridin-4-amine;N-(3-methyl-2H-pyrazolo[4,3-c]pyridin-4-yl)-1,3-benzothiazol-6-amine;3-methyl-N-(pyridin-2-ylmethyl)-2H-pyrazolo[4,3-c]pyridin-4-amine
CID 157591965

Frequently Asked Questions

What is the IUPAC name of 5-(1,3-benzothiazol-6-yl)-6-(3-methylpyrazol-1-yl)pyrazin-2-amine;5-(7-chloro-1H-indazol-5-yl)-6-phenylpyrazin-2-amine;5-(1H-indazol-5-yl)-6-(3-methylpyrazol-1-yl)pyrazin-2-amine;6-(1-methylpyrazol-3-yl)-5-quinolin-6-ylpyrazin-2-amine;6-(2-methyl-1,3-thiazol-5-yl)-5-quinolin-6-ylpyrazin-2-amine?
The IUPAC name of 5-(1,3-benzothiazol-6-yl)-6-(3-methylpyrazol-1-yl)pyrazin-2-amine;5-(7-chloro-1H-indazol-5-yl)-6-phenylpyrazin-2-amine;5-(1H-indazol-5-yl)-6-(3-methylpyrazol-1-yl)pyrazin-2-amine;6-(1-methylpyrazol-3-yl)-5-quinolin-6-ylpyrazin-2-amine;6-(2-methyl-1,3-thiazol-5-yl)-5-quinolin-6-ylpyrazin-2-amine (CID 159218172) is 5-(1,3-benzothiazol-6-yl)-6-(3-methylpyrazol-1-yl)pyrazin-2-amine;5-(7-chloro-1H-indazol-5-yl)-6-phenylpyrazin-2-amine;5-(1H-indazol-5-yl)-6-(3-methylpyrazol-1-yl)pyrazin-2-amine;6-(1-methylpyrazol-3-yl)-5-quinolin-6-ylpyrazin-2-amine;6-(2-methyl-1,3-thiazol-5-yl)-5-quinolin-6-ylpyrazin-2-amine.
What is the SMILES notation for 5-(1,3-benzothiazol-6-yl)-6-(3-methylpyrazol-1-yl)pyrazin-2-amine;5-(7-chloro-1H-indazol-5-yl)-6-phenylpyrazin-2-amine;5-(1H-indazol-5-yl)-6-(3-methylpyrazol-1-yl)pyrazin-2-amine;6-(1-methylpyrazol-3-yl)-5-quinolin-6-ylpyrazin-2-amine;6-(2-methyl-1,3-thiazol-5-yl)-5-quinolin-6-ylpyrazin-2-amine?
The canonical SMILES for 5-(1,3-benzothiazol-6-yl)-6-(3-methylpyrazol-1-yl)pyrazin-2-amine;5-(7-chloro-1H-indazol-5-yl)-6-phenylpyrazin-2-amine;5-(1H-indazol-5-yl)-6-(3-methylpyrazol-1-yl)pyrazin-2-amine;6-(1-methylpyrazol-3-yl)-5-quinolin-6-ylpyrazin-2-amine;6-(2-methyl-1,3-thiazol-5-yl)-5-quinolin-6-ylpyrazin-2-amine is Cc1ccn(-c2nc(N)cnc2-c2ccc3[nH]ncc3c2)n1.Cc1ccn(-c2nc(N)cnc2-c2ccc3ncsc3c2)n1.Cc1ncc(-c2nc(N)cnc2-c2ccc3ncccc3c2)s1.Cn1ccc(-c2nc(N)cnc2-c2ccc3ncccc3c2)n1.Nc1cnc(-c2cc(Cl)c3[nH]ncc3c2)c(-c2ccccc2)n1.
What is the InChIKey of 5-(1,3-benzothiazol-6-yl)-6-(3-methylpyrazol-1-yl)pyrazin-2-amine;5-(7-chloro-1H-indazol-5-yl)-6-phenylpyrazin-2-amine;5-(1H-indazol-5-yl)-6-(3-methylpyrazol-1-yl)pyrazin-2-amine;6-(1-methylpyrazol-3-yl)-5-quinolin-6-ylpyrazin-2-amine;6-(2-methyl-1,3-thiazol-5-yl)-5-quinolin-6-ylpyrazin-2-amine?
The InChIKey is KRIONTFWCDFTCO-UHFFFAOYSA-N. The full InChI is InChI=1S/C17H12ClN5.C17H14N6.C17H13N5S.C15H13N7.C15H12N6S/c18-13-7-11(6-12-8-21-23-15(12)13)16-17(22-14(19)9-20-16)10-4-2-1-3-5-10;1-23-8-6-14(22-23)17-16(20-10-15(18)21-17)12-4-5-13-11(9-12)3-2-7-19-13;1-10-20-8-14(23-10)17-16(21-9-15(18)22-17)12-4-5-13-11(7-12)3-2-6-19-13;1-9-4-5-22(21-9)15-14(17-8-13(16)19-15)10-2-3-12-11(6-10)7-18-20-12;1-9-4-5-21(20-9)15-14(17-7-13(16)19-15)10-2-3-11-12(6-10)22-8-18-11/h1-9H,(H2,19,22)(H,21,23);2-10H,1H3,(H2,18,21);2-9H,1H3,(H2,18,22);2-8H,1H3,(H2,16,19)(H,18,20);2-8H,1H3,(H2,16,19).
What are the key properties of 5-(1,3-benzothiazol-6-yl)-6-(3-methylpyrazol-1-yl)pyrazin-2-amine;5-(7-chloro-1H-indazol-5-yl)-6-phenylpyrazin-2-amine;5-(1H-indazol-5-yl)-6-(3-methylpyrazol-1-yl)pyrazin-2-amine;6-(1-methylpyrazol-3-yl)-5-quinolin-6-ylpyrazin-2-amine;6-(2-methyl-1,3-thiazol-5-yl)-5-quinolin-6-ylpyrazin-2-amine?
5-(1,3-benzothiazol-6-yl)-6-(3-methylpyrazol-1-yl)pyrazin-2-amine;5-(7-chloro-1H-indazol-5-yl)-6-phenylpyrazin-2-amine;5-(1H-indazol-5-yl)-6-(3-methylpyrazol-1-yl)pyrazin-2-amine;6-(1-methylpyrazol-3-yl)-5-quinolin-6-ylpyrazin-2-amine;6-(2-methyl-1,3-thiazol-5-yl)-5-quinolin-6-ylpyrazin-2-amine has a molecular weight of 1543.19 g/mol, XLogP of 15.23, 10 rotatable bonds, 7 hydrogen bond donors, and 29 hydrogen bond acceptors.
Where does this data come from?
All data for 5-(1,3-benzothiazol-6-yl)-6-(3-methylpyrazol-1-yl)pyrazin-2-amine;5-(7-chloro-1H-indazol-5-yl)-6-phenylpyrazin-2-amine;5-(1H-indazol-5-yl)-6-(3-methylpyrazol-1-yl)pyrazin-2-amine;6-(1-methylpyrazol-3-yl)-5-quinolin-6-ylpyrazin-2-amine;6-(2-methyl-1,3-thiazol-5-yl)-5-quinolin-6-ylpyrazin-2-amine is sourced from PubChem (CID 159218172), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).