[3-[6-[4-(difluoromethoxy)anilino]pyrazin-2-yl]imidazo[1,2-a]pyridin-2-yl]methanol;2-[4-(difluoromethoxy)anilino]-6-[2-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyridine-4-carbonitrile;2-[2-(1-hydroxyethyl)benzimidazol-1-yl]-6-[4-(trifluoromethyl)anilino]pyridine-4-carbonitrile;[3-[6-(4-methylanilino)pyrazin-2-yl]imidazo[1,2-a]pyridin-2-yl]methanol;[3-[6-[4-(trifluoromethoxy)anilino]pyrazin-2-yl]imidazo[1,2-a]pyridin-2-yl]methanol

C100H74F13N25O7 — CID 159228825

About [3-[6-[4-(difluoromethoxy)anilino]pyrazin-2-yl]imidazo[1,2-a]pyridin-2-yl]methanol;2-[4-(difluoromethoxy)anilino]-6-[2-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyridine-4-carbonitrile;2-[2-(1-hydroxyethyl)benzimidazol-1-yl]-6-[4-(trifluoromethyl)anilino]pyridine-4-carbonitrile;[3-[6-(4-methylanilino)pyrazin-2-yl]imidazo[1,2-a]pyridin-2-yl]methanol;[3-[6-[4-(trifluoromethoxy)anilino]pyrazin-2-yl]imidazo[1,2-a]pyridin-2-yl]methanol

[3-[6-[4-(difluoromethoxy)anilino]pyrazin-2-yl]imidazo[1,2-a]pyridin-2-yl]methanol;2-[4-(difluoromethoxy)anilino]-6-[2-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyridine-4-carbonitrile;2-[2-(1-hydroxyethyl)benzimidazol-1-yl]-6-[4-(trifluoromethyl)anilino]pyridine-4-carbonitrile;[3-[6-(4-methylanilino)pyrazin-2-yl]imidazo[1,2-a]pyridin-2-yl]methanol;[3-[6-[4-(trifluoromethoxy)anilino]pyrazin-2-yl]imidazo[1,2-a]pyridin-2-yl]methanol (PubChem CID 159228825) has the molecular formula C100H74F13N25O7 and a molecular weight of 1984.83 g/mol. Its IUPAC name is [3-[6-[4-(difluoromethoxy)anilino]pyrazin-2-yl]imidazo[1,2-a]pyridin-2-yl]methanol;2-[4-(difluoromethoxy)anilino]-6-[2-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyridine-4-carbonitrile;2-[2-(1-hydroxyethyl)benzimidazol-1-yl]-6-[4-(trifluoromethyl)anilino]pyridine-4-carbonitrile;[3-[6-(4-methylanilino)pyrazin-2-yl]imidazo[1,2-a]pyridin-2-yl]methanol;[3-[6-[4-(trifluoromethoxy)anilino]pyrazin-2-yl]imidazo[1,2-a]pyridin-2-yl]methanol.

Molecular Properties

• Compound Name: [3-[6-[4-(difluoromethoxy)anilino]pyrazin-2-yl]imidazo[1,2-a]pyridin-2-yl]methanol;2-[4-(difluoromethoxy)anilino]-6-[2-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyridine-4-carbonitrile;2-[2-(1-hydroxyethyl)benzimidazol-1-yl]-6-[4-(trifluoromethyl)anilino]pyridine-4-carbonitrile;[3-[6-(4-methylanilino)pyrazin-2-yl]imidazo[1,2-a]pyridin-2-yl]methanol;[3-[6-[4-(trifluoromethoxy)anilino]pyrazin-2-yl]imidazo[1,2-a]pyridin-2-yl]methanol
• PubChem CID: 159228825
• Molecular Formula: C100H74F13N25O7
• Molecular Weight: 1984.83 g/mol
• Exact Mass: 1983.60
• IUPAC Name: [3-[6-[4-(difluoromethoxy)anilino]pyrazin-2-yl]imidazo[1,2-a]pyridin-2-yl]methanol;2-[4-(difluoromethoxy)anilino]-6-[2-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyridine-4-carbonitrile;2-[2-(1-hydroxyethyl)benzimidazol-1-yl]-6-[4-(trifluoromethyl)anilino]pyridine-4-carbonitrile;[3-[6-(4-methylanilino)pyrazin-2-yl]imidazo[1,2-a]pyridin-2-yl]methanol;[3-[6-[4-(trifluoromethoxy)anilino]pyrazin-2-yl]imidazo[1,2-a]pyridin-2-yl]methanol
• SMILES: CC(O)c1nc2ccccc2n1-c1cc(C#N)cc(Nc2ccc(C(F)(F)F)cc2)n1.Cc1ccc(Nc2cncc(-c3c(CO)nc4ccccn34)n2)cc1.N#Cc1cc(Nc2ccc(OC(F)F)cc2)nc(-c2c(C(F)(F)F)nc3ccccn23)c1.OCc1nc2ccccn2c1-c1cncc(Nc2ccc(OC(F)(F)F)cc2)n1.OCc1nc2ccccn2c1-c1cncc(Nc2ccc(OC(F)F)cc2)n1
• InChI: InChI=1S/C22H16F3N5O.C21H12F5N5O.C19H14F3N5O2.C19H15F2N5O2.C19H17N5O/c1-13(31)21-28-17-4-2-3-5-18(17)30(21)20-11-14(12-26)10-19(29-20)27-16-8-6-15(7-9-16)22(23,24)25;22-20(23)32-14-6-4-13(5-7-14)28-16-10-12(11-27)9-15(29-16)18-19(21(24,25)26)30-17-3-1-2-8-31(17)18;20-19(21,22)29-13-6-4-12(5-7-13)24-16-10-23-9-14(25-16)18-15(11-28)26-17-3-1-2-8-27(17)18;20-19(21)28-13-6-4-12(5-7-13)23-16-10-22-9-14(24-16)18-15(11-27)25-17-3-1-2-8-26(17)18;1-13-5-7-14(8-6-13)21-17-11-20-10-15(22-17)19-16(12-25)23-18-4-2-3-9-24(18)19/h2-11,13,31H,1H3,(H,27,29);1-10,20H,(H,28,29);1-10,28H,11H2,(H,24,25);1-10,19,27H,11H2,(H,23,24);2-11,25H,12H2,1H3,(H,21,22)
• InChIKey: KSQCHKHOVSGAII-UHFFFAOYSA-N
• XLogP: 21.63
• TPSA: 406.48 Ų
• H-Bond Donors: 9
• H-Bond Acceptors: 32
• Rotatable Bonds: 24
• Heavy Atoms: 145
• Complexity: —

Lipinski Rule of Five

4 violations

Rule	Value
MW ≤ 500	1984.83
LogP ≤ 5	21.63
H-Bond Donors ≤ 5	9
H-Bond Acceptors ≤ 10	32

Frequently Asked Questions

What is the IUPAC name of [3-[6-[4-(difluoromethoxy)anilino]pyrazin-2-yl]imidazo[1,2-a]pyridin-2-yl]methanol;2-[4-(difluoromethoxy)anilino]-6-[2-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyridine-4-carbonitrile;2-[2-(1-hydroxyethyl)benzimidazol-1-yl]-6-[4-(trifluoromethyl)anilino]pyridine-4-carbonitrile;[3-[6-(4-methylanilino)pyrazin-2-yl]imidazo[1,2-a]pyridin-2-yl]methanol;[3-[6-[4-(trifluoromethoxy)anilino]pyrazin-2-yl]imidazo[1,2-a]pyridin-2-yl]methanol?

The IUPAC name of [3-[6-[4-(difluoromethoxy)anilino]pyrazin-2-yl]imidazo[1,2-a]pyridin-2-yl]methanol;2-[4-(difluoromethoxy)anilino]-6-[2-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyridine-4-carbonitrile;2-[2-(1-hydroxyethyl)benzimidazol-1-yl]-6-[4-(trifluoromethyl)anilino]pyridine-4-carbonitrile;[3-[6-(4-methylanilino)pyrazin-2-yl]imidazo[1,2-a]pyridin-2-yl]methanol;[3-[6-[4-(trifluoromethoxy)anilino]pyrazin-2-yl]imidazo[1,2-a]pyridin-2-yl]methanol (CID 159228825) is [3-[6-[4-(difluoromethoxy)anilino]pyrazin-2-yl]imidazo[1,2-a]pyridin-2-yl]methanol;2-[4-(difluoromethoxy)anilino]-6-[2-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyridine-4-carbonitrile;2-[2-(1-hydroxyethyl)benzimidazol-1-yl]-6-[4-(trifluoromethyl)anilino]pyridine-4-carbonitrile;[3-[6-(4-methylanilino)pyrazin-2-yl]imidazo[1,2-a]pyridin-2-yl]methanol;[3-[6-[4-(trifluoromethoxy)anilino]pyrazin-2-yl]imidazo[1,2-a]pyridin-2-yl]methanol.

What is the SMILES notation for [3-[6-[4-(difluoromethoxy)anilino]pyrazin-2-yl]imidazo[1,2-a]pyridin-2-yl]methanol;2-[4-(difluoromethoxy)anilino]-6-[2-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyridine-4-carbonitrile;2-[2-(1-hydroxyethyl)benzimidazol-1-yl]-6-[4-(trifluoromethyl)anilino]pyridine-4-carbonitrile;[3-[6-(4-methylanilino)pyrazin-2-yl]imidazo[1,2-a]pyridin-2-yl]methanol;[3-[6-[4-(trifluoromethoxy)anilino]pyrazin-2-yl]imidazo[1,2-a]pyridin-2-yl]methanol?

The canonical SMILES for [3-[6-[4-(difluoromethoxy)anilino]pyrazin-2-yl]imidazo[1,2-a]pyridin-2-yl]methanol;2-[4-(difluoromethoxy)anilino]-6-[2-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyridine-4-carbonitrile;2-[2-(1-hydroxyethyl)benzimidazol-1-yl]-6-[4-(trifluoromethyl)anilino]pyridine-4-carbonitrile;[3-[6-(4-methylanilino)pyrazin-2-yl]imidazo[1,2-a]pyridin-2-yl]methanol;[3-[6-[4-(trifluoromethoxy)anilino]pyrazin-2-yl]imidazo[1,2-a]pyridin-2-yl]methanol is CC(O)c1nc2ccccc2n1-c1cc(C#N)cc(Nc2ccc(C(F)(F)F)cc2)n1.Cc1ccc(Nc2cncc(-c3c(CO)nc4ccccn34)n2)cc1.N#Cc1cc(Nc2ccc(OC(F)F)cc2)nc(-c2c(C(F)(F)F)nc3ccccn23)c1.OCc1nc2ccccn2c1-c1cncc(Nc2ccc(OC(F)(F)F)cc2)n1.OCc1nc2ccccn2c1-c1cncc(Nc2ccc(OC(F)F)cc2)n1.

What is the InChIKey of [3-[6-[4-(difluoromethoxy)anilino]pyrazin-2-yl]imidazo[1,2-a]pyridin-2-yl]methanol;2-[4-(difluoromethoxy)anilino]-6-[2-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyridine-4-carbonitrile;2-[2-(1-hydroxyethyl)benzimidazol-1-yl]-6-[4-(trifluoromethyl)anilino]pyridine-4-carbonitrile;[3-[6-(4-methylanilino)pyrazin-2-yl]imidazo[1,2-a]pyridin-2-yl]methanol;[3-[6-[4-(trifluoromethoxy)anilino]pyrazin-2-yl]imidazo[1,2-a]pyridin-2-yl]methanol?

The InChIKey is KSQCHKHOVSGAII-UHFFFAOYSA-N. The full InChI is InChI=1S/C22H16F3N5O.C21H12F5N5O.C19H14F3N5O2.C19H15F2N5O2.C19H17N5O/c1-13(31)21-28-17-4-2-3-5-18(17)30(21)20-11-14(12-26)10-19(29-20)27-16-8-6-15(7-9-16)22(23,24)25;22-20(23)32-14-6-4-13(5-7-14)28-16-10-12(11-27)9-15(29-16)18-19(21(24,25)26)30-17-3-1-2-8-31(17)18;20-19(21,22)29-13-6-4-12(5-7-13)24-16-10-23-9-14(25-16)18-15(11-28)26-17-3-1-2-8-27(17)18;20-19(21)28-13-6-4-12(5-7-13)23-16-10-22-9-14(24-16)18-15(11-27)25-17-3-1-2-8-26(17)18;1-13-5-7-14(8-6-13)21-17-11-20-10-15(22-17)19-16(12-25)23-18-4-2-3-9-24(18)19/h2-11,13,31H,1H3,(H,27,29);1-10,20H,(H,28,29);1-10,28H,11H2,(H,24,25);1-10,19,27H,11H2,(H,23,24);2-11,25H,12H2,1H3,(H,21,22).

What are the key properties of [3-[6-[4-(difluoromethoxy)anilino]pyrazin-2-yl]imidazo[1,2-a]pyridin-2-yl]methanol;2-[4-(difluoromethoxy)anilino]-6-[2-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyridine-4-carbonitrile;2-[2-(1-hydroxyethyl)benzimidazol-1-yl]-6-[4-(trifluoromethyl)anilino]pyridine-4-carbonitrile;[3-[6-(4-methylanilino)pyrazin-2-yl]imidazo[1,2-a]pyridin-2-yl]methanol;[3-[6-[4-(trifluoromethoxy)anilino]pyrazin-2-yl]imidazo[1,2-a]pyridin-2-yl]methanol?

[3-[6-[4-(difluoromethoxy)anilino]pyrazin-2-yl]imidazo[1,2-a]pyridin-2-yl]methanol;2-[4-(difluoromethoxy)anilino]-6-[2-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyridine-4-carbonitrile;2-[2-(1-hydroxyethyl)benzimidazol-1-yl]-6-[4-(trifluoromethyl)anilino]pyridine-4-carbonitrile;[3-[6-(4-methylanilino)pyrazin-2-yl]imidazo[1,2-a]pyridin-2-yl]methanol;[3-[6-[4-(trifluoromethoxy)anilino]pyrazin-2-yl]imidazo[1,2-a]pyridin-2-yl]methanol has a molecular weight of 1984.83 g/mol, XLogP of 21.63, 24 rotatable bonds, 9 hydrogen bond donors, and 32 hydrogen bond acceptors.

Where does this data come from?

All data for [3-[6-[4-(difluoromethoxy)anilino]pyrazin-2-yl]imidazo[1,2-a]pyridin-2-yl]methanol;2-[4-(difluoromethoxy)anilino]-6-[2-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyridine-4-carbonitrile;2-[2-(1-hydroxyethyl)benzimidazol-1-yl]-6-[4-(trifluoromethyl)anilino]pyridine-4-carbonitrile;[3-[6-(4-methylanilino)pyrazin-2-yl]imidazo[1,2-a]pyridin-2-yl]methanol;[3-[6-[4-(trifluoromethoxy)anilino]pyrazin-2-yl]imidazo[1,2-a]pyridin-2-yl]methanol is sourced from PubChem (CID 159228825), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).