2-chloro-N-[5-[3-(2-fluorophenyl)-1-methylpyrazol-5-yl]-2-pyridinyl]benzamide;2-chloro-N-[5-[3-(furan-2-yl)-1-methylpyrazol-5-yl]-2-pyridinyl]benzamide;2,6-difluoro-N-[5-[3-(2-fluorophenyl)-1-methylpyrazol-5-yl]-2-pyridinyl]benzamide;2-fluoro-N-[5-[3-(2-fluorophenyl)-1-methylpyrazol-5-yl]-2-pyridinyl]benzamide;N-[5-[3-(2-fluorophenyl)-1-methylpyrazol-5-yl]-2-pyridinyl]-4-methyl-1,2-thiazole-5-carboxamide;N-[5-[3-(2-fluorophenyl)-1-methylpyrazol-5-yl]-2-pyridinyl]-3-methylthiophene-2-carboxamide

C127H95Cl2F8N25O7S2 — CID 159231908

About 2-chloro-N-[5-[3-(2-fluorophenyl)-1-methylpyrazol-5-yl]-2-pyridinyl]benzamide;2-chloro-N-[5-[3-(furan-2-yl)-1-methylpyrazol-5-yl]-2-pyridinyl]benzamide;2,6-difluoro-N-[5-[3-(2-fluorophenyl)-1-methylpyrazol-5-yl]-2-pyridinyl]benzamide;2-fluoro-N-[5-[3-(2-fluorophenyl)-1-methylpyrazol-5-yl]-2-pyridinyl]benzamide;N-[5-[3-(2-fluorophenyl)-1-methylpyrazol-5-yl]-2-pyridinyl]-4-methyl-1,2-thiazole-5-carboxamide;N-[5-[3-(2-fluorophenyl)-1-methylpyrazol-5-yl]-2-pyridinyl]-3-methylthiophene-2-carboxamide

2-chloro-N-[5-[3-(2-fluorophenyl)-1-methylpyrazol-5-yl]-2-pyridinyl]benzamide;2-chloro-N-[5-[3-(furan-2-yl)-1-methylpyrazol-5-yl]-2-pyridinyl]benzamide;2,6-difluoro-N-[5-[3-(2-fluorophenyl)-1-methylpyrazol-5-yl]-2-pyridinyl]benzamide;2-fluoro-N-[5-[3-(2-fluorophenyl)-1-methylpyrazol-5-yl]-2-pyridinyl]benzamide;N-[5-[3-(2-fluorophenyl)-1-methylpyrazol-5-yl]-2-pyridinyl]-4-methyl-1,2-thiazole-5-carboxamide;N-[5-[3-(2-fluorophenyl)-1-methylpyrazol-5-yl]-2-pyridinyl]-3-methylthiophene-2-carboxamide (PubChem CID 159231908) has the molecular formula C127H95Cl2F8N25O7S2 and a molecular weight of 2370.35 g/mol. Its IUPAC name is 2-chloro-N-[5-[3-(2-fluorophenyl)-1-methylpyrazol-5-yl]-2-pyridinyl]benzamide;2-chloro-N-[5-[3-(furan-2-yl)-1-methylpyrazol-5-yl]-2-pyridinyl]benzamide;2,6-difluoro-N-[5-[3-(2-fluorophenyl)-1-methylpyrazol-5-yl]-2-pyridinyl]benzamide;2-fluoro-N-[5-[3-(2-fluorophenyl)-1-methylpyrazol-5-yl]-2-pyridinyl]benzamide;N-[5-[3-(2-fluorophenyl)-1-methylpyrazol-5-yl]-2-pyridinyl]-4-methyl-1,2-thiazole-5-carboxamide;N-[5-[3-(2-fluorophenyl)-1-methylpyrazol-5-yl]-2-pyridinyl]-3-methylthiophene-2-carboxamide.

Molecular Properties

• Compound Name: 2-chloro-N-[5-[3-(2-fluorophenyl)-1-methylpyrazol-5-yl]-2-pyridinyl]benzamide;2-chloro-N-[5-[3-(furan-2-yl)-1-methylpyrazol-5-yl]-2-pyridinyl]benzamide;2,6-difluoro-N-[5-[3-(2-fluorophenyl)-1-methylpyrazol-5-yl]-2-pyridinyl]benzamide;2-fluoro-N-[5-[3-(2-fluorophenyl)-1-methylpyrazol-5-yl]-2-pyridinyl]benzamide;N-[5-[3-(2-fluorophenyl)-1-methylpyrazol-5-yl]-2-pyridinyl]-4-methyl-1,2-thiazole-5-carboxamide;N-[5-[3-(2-fluorophenyl)-1-methylpyrazol-5-yl]-2-pyridinyl]-3-methylthiophene-2-carboxamide
• PubChem CID: 159231908
• Molecular Formula: C127H95Cl2F8N25O7S2
• Molecular Weight: 2370.35 g/mol
• Exact Mass: 2367.65
• IUPAC Name: 2-chloro-N-[5-[3-(2-fluorophenyl)-1-methylpyrazol-5-yl]-2-pyridinyl]benzamide;2-chloro-N-[5-[3-(furan-2-yl)-1-methylpyrazol-5-yl]-2-pyridinyl]benzamide;2,6-difluoro-N-[5-[3-(2-fluorophenyl)-1-methylpyrazol-5-yl]-2-pyridinyl]benzamide;2-fluoro-N-[5-[3-(2-fluorophenyl)-1-methylpyrazol-5-yl]-2-pyridinyl]benzamide;N-[5-[3-(2-fluorophenyl)-1-methylpyrazol-5-yl]-2-pyridinyl]-4-methyl-1,2-thiazole-5-carboxamide;N-[5-[3-(2-fluorophenyl)-1-methylpyrazol-5-yl]-2-pyridinyl]-3-methylthiophene-2-carboxamide
• SMILES: Cc1ccsc1C(=O)Nc1ccc(-c2cc(-c3ccccc3F)nn2C)cn1.Cc1cnsc1C(=O)Nc1ccc(-c2cc(-c3ccccc3F)nn2C)cn1.Cn1nc(-c2ccccc2F)cc1-c1ccc(NC(=O)c2c(F)cccc2F)nc1.Cn1nc(-c2ccccc2F)cc1-c1ccc(NC(=O)c2ccccc2Cl)nc1.Cn1nc(-c2ccccc2F)cc1-c1ccc(NC(=O)c2ccccc2F)nc1.Cn1nc(-c2ccco2)cc1-c1ccc(NC(=O)c2ccccc2Cl)nc1
• InChI: InChI=1S/C22H16ClFN4O.C22H15F3N4O.C22H16F2N4O.C21H17FN4OS.C20H15ClN4O2.C20H16FN5OS/c1-28-20(12-19(27-28)16-7-3-5-9-18(16)24)14-10-11-21(25-13-14)26-22(29)15-6-2-4-8-17(15)23;1-29-19(11-18(28-29)14-5-2-3-6-15(14)23)13-9-10-20(26-12-13)27-22(30)21-16(24)7-4-8-17(21)25;1-28-20(12-19(27-28)15-6-2-4-8-17(15)23)14-10-11-21(25-13-14)26-22(29)16-7-3-5-9-18(16)24;1-13-9-10-28-20(13)21(27)24-19-8-7-14(12-23-19)18-11-17(25-26(18)2)15-5-3-4-6-16(15)22;1-25-17(11-16(24-25)18-7-4-10-27-18)13-8-9-19(22-12-13)23-20(26)14-5-2-3-6-15(14)21;1-12-10-23-28-19(12)20(27)24-18-8-7-13(11-22-18)17-9-16(25-26(17)2)14-5-3-4-6-15(14)21/h2-13H,1H3,(H,25,26,29);2-12H,1H3,(H,26,27,30);2-13H,1H3,(H,25,26,29);3-12H,1-2H3,(H,23,24,27);2-12H,1H3,(H,22,23,26);3-11H,1-2H3,(H,22,24,27)
• InChIKey: KSZXUSSMDYTQOK-UHFFFAOYSA-N
• XLogP: 28.56
• TPSA: 384.89 Ų
• H-Bond Donors: 6
• H-Bond Acceptors: 28
• Rotatable Bonds: 24
• Heavy Atoms: 171
• Complexity: —

Lipinski Rule of Five

4 violations

Rule	Value
MW ≤ 500	2370.35
LogP ≤ 5	28.56
H-Bond Donors ≤ 5	6
H-Bond Acceptors ≤ 10	28

Frequently Asked Questions

What is the IUPAC name of 2-chloro-N-[5-[3-(2-fluorophenyl)-1-methylpyrazol-5-yl]-2-pyridinyl]benzamide;2-chloro-N-[5-[3-(furan-2-yl)-1-methylpyrazol-5-yl]-2-pyridinyl]benzamide;2,6-difluoro-N-[5-[3-(2-fluorophenyl)-1-methylpyrazol-5-yl]-2-pyridinyl]benzamide;2-fluoro-N-[5-[3-(2-fluorophenyl)-1-methylpyrazol-5-yl]-2-pyridinyl]benzamide;N-[5-[3-(2-fluorophenyl)-1-methylpyrazol-5-yl]-2-pyridinyl]-4-methyl-1,2-thiazole-5-carboxamide;N-[5-[3-(2-fluorophenyl)-1-methylpyrazol-5-yl]-2-pyridinyl]-3-methylthiophene-2-carboxamide?

The IUPAC name of 2-chloro-N-[5-[3-(2-fluorophenyl)-1-methylpyrazol-5-yl]-2-pyridinyl]benzamide;2-chloro-N-[5-[3-(furan-2-yl)-1-methylpyrazol-5-yl]-2-pyridinyl]benzamide;2,6-difluoro-N-[5-[3-(2-fluorophenyl)-1-methylpyrazol-5-yl]-2-pyridinyl]benzamide;2-fluoro-N-[5-[3-(2-fluorophenyl)-1-methylpyrazol-5-yl]-2-pyridinyl]benzamide;N-[5-[3-(2-fluorophenyl)-1-methylpyrazol-5-yl]-2-pyridinyl]-4-methyl-1,2-thiazole-5-carboxamide;N-[5-[3-(2-fluorophenyl)-1-methylpyrazol-5-yl]-2-pyridinyl]-3-methylthiophene-2-carboxamide (CID 159231908) is 2-chloro-N-[5-[3-(2-fluorophenyl)-1-methylpyrazol-5-yl]-2-pyridinyl]benzamide;2-chloro-N-[5-[3-(furan-2-yl)-1-methylpyrazol-5-yl]-2-pyridinyl]benzamide;2,6-difluoro-N-[5-[3-(2-fluorophenyl)-1-methylpyrazol-5-yl]-2-pyridinyl]benzamide;2-fluoro-N-[5-[3-(2-fluorophenyl)-1-methylpyrazol-5-yl]-2-pyridinyl]benzamide;N-[5-[3-(2-fluorophenyl)-1-methylpyrazol-5-yl]-2-pyridinyl]-4-methyl-1,2-thiazole-5-carboxamide;N-[5-[3-(2-fluorophenyl)-1-methylpyrazol-5-yl]-2-pyridinyl]-3-methylthiophene-2-carboxamide.

What is the SMILES notation for 2-chloro-N-[5-[3-(2-fluorophenyl)-1-methylpyrazol-5-yl]-2-pyridinyl]benzamide;2-chloro-N-[5-[3-(furan-2-yl)-1-methylpyrazol-5-yl]-2-pyridinyl]benzamide;2,6-difluoro-N-[5-[3-(2-fluorophenyl)-1-methylpyrazol-5-yl]-2-pyridinyl]benzamide;2-fluoro-N-[5-[3-(2-fluorophenyl)-1-methylpyrazol-5-yl]-2-pyridinyl]benzamide;N-[5-[3-(2-fluorophenyl)-1-methylpyrazol-5-yl]-2-pyridinyl]-4-methyl-1,2-thiazole-5-carboxamide;N-[5-[3-(2-fluorophenyl)-1-methylpyrazol-5-yl]-2-pyridinyl]-3-methylthiophene-2-carboxamide?

The canonical SMILES for 2-chloro-N-[5-[3-(2-fluorophenyl)-1-methylpyrazol-5-yl]-2-pyridinyl]benzamide;2-chloro-N-[5-[3-(furan-2-yl)-1-methylpyrazol-5-yl]-2-pyridinyl]benzamide;2,6-difluoro-N-[5-[3-(2-fluorophenyl)-1-methylpyrazol-5-yl]-2-pyridinyl]benzamide;2-fluoro-N-[5-[3-(2-fluorophenyl)-1-methylpyrazol-5-yl]-2-pyridinyl]benzamide;N-[5-[3-(2-fluorophenyl)-1-methylpyrazol-5-yl]-2-pyridinyl]-4-methyl-1,2-thiazole-5-carboxamide;N-[5-[3-(2-fluorophenyl)-1-methylpyrazol-5-yl]-2-pyridinyl]-3-methylthiophene-2-carboxamide is Cc1ccsc1C(=O)Nc1ccc(-c2cc(-c3ccccc3F)nn2C)cn1.Cc1cnsc1C(=O)Nc1ccc(-c2cc(-c3ccccc3F)nn2C)cn1.Cn1nc(-c2ccccc2F)cc1-c1ccc(NC(=O)c2c(F)cccc2F)nc1.Cn1nc(-c2ccccc2F)cc1-c1ccc(NC(=O)c2ccccc2Cl)nc1.Cn1nc(-c2ccccc2F)cc1-c1ccc(NC(=O)c2ccccc2F)nc1.Cn1nc(-c2ccco2)cc1-c1ccc(NC(=O)c2ccccc2Cl)nc1.

What is the InChIKey of 2-chloro-N-[5-[3-(2-fluorophenyl)-1-methylpyrazol-5-yl]-2-pyridinyl]benzamide;2-chloro-N-[5-[3-(furan-2-yl)-1-methylpyrazol-5-yl]-2-pyridinyl]benzamide;2,6-difluoro-N-[5-[3-(2-fluorophenyl)-1-methylpyrazol-5-yl]-2-pyridinyl]benzamide;2-fluoro-N-[5-[3-(2-fluorophenyl)-1-methylpyrazol-5-yl]-2-pyridinyl]benzamide;N-[5-[3-(2-fluorophenyl)-1-methylpyrazol-5-yl]-2-pyridinyl]-4-methyl-1,2-thiazole-5-carboxamide;N-[5-[3-(2-fluorophenyl)-1-methylpyrazol-5-yl]-2-pyridinyl]-3-methylthiophene-2-carboxamide?

The InChIKey is KSZXUSSMDYTQOK-UHFFFAOYSA-N. The full InChI is InChI=1S/C22H16ClFN4O.C22H15F3N4O.C22H16F2N4O.C21H17FN4OS.C20H15ClN4O2.C20H16FN5OS/c1-28-20(12-19(27-28)16-7-3-5-9-18(16)24)14-10-11-21(25-13-14)26-22(29)15-6-2-4-8-17(15)23;1-29-19(11-18(28-29)14-5-2-3-6-15(14)23)13-9-10-20(26-12-13)27-22(30)21-16(24)7-4-8-17(21)25;1-28-20(12-19(27-28)15-6-2-4-8-17(15)23)14-10-11-21(25-13-14)26-22(29)16-7-3-5-9-18(16)24;1-13-9-10-28-20(13)21(27)24-19-8-7-14(12-23-19)18-11-17(25-26(18)2)15-5-3-4-6-16(15)22;1-25-17(11-16(24-25)18-7-4-10-27-18)13-8-9-19(22-12-13)23-20(26)14-5-2-3-6-15(14)21;1-12-10-23-28-19(12)20(27)24-18-8-7-13(11-22-18)17-9-16(25-26(17)2)14-5-3-4-6-15(14)21/h2-13H,1H3,(H,25,26,29);2-12H,1H3,(H,26,27,30);2-13H,1H3,(H,25,26,29);3-12H,1-2H3,(H,23,24,27);2-12H,1H3,(H,22,23,26);3-11H,1-2H3,(H,22,24,27).

What are the key properties of 2-chloro-N-[5-[3-(2-fluorophenyl)-1-methylpyrazol-5-yl]-2-pyridinyl]benzamide;2-chloro-N-[5-[3-(furan-2-yl)-1-methylpyrazol-5-yl]-2-pyridinyl]benzamide;2,6-difluoro-N-[5-[3-(2-fluorophenyl)-1-methylpyrazol-5-yl]-2-pyridinyl]benzamide;2-fluoro-N-[5-[3-(2-fluorophenyl)-1-methylpyrazol-5-yl]-2-pyridinyl]benzamide;N-[5-[3-(2-fluorophenyl)-1-methylpyrazol-5-yl]-2-pyridinyl]-4-methyl-1,2-thiazole-5-carboxamide;N-[5-[3-(2-fluorophenyl)-1-methylpyrazol-5-yl]-2-pyridinyl]-3-methylthiophene-2-carboxamide?

2-chloro-N-[5-[3-(2-fluorophenyl)-1-methylpyrazol-5-yl]-2-pyridinyl]benzamide;2-chloro-N-[5-[3-(furan-2-yl)-1-methylpyrazol-5-yl]-2-pyridinyl]benzamide;2,6-difluoro-N-[5-[3-(2-fluorophenyl)-1-methylpyrazol-5-yl]-2-pyridinyl]benzamide;2-fluoro-N-[5-[3-(2-fluorophenyl)-1-methylpyrazol-5-yl]-2-pyridinyl]benzamide;N-[5-[3-(2-fluorophenyl)-1-methylpyrazol-5-yl]-2-pyridinyl]-4-methyl-1,2-thiazole-5-carboxamide;N-[5-[3-(2-fluorophenyl)-1-methylpyrazol-5-yl]-2-pyridinyl]-3-methylthiophene-2-carboxamide has a molecular weight of 2370.35 g/mol, XLogP of 28.56, 24 rotatable bonds, 6 hydrogen bond donors, and 28 hydrogen bond acceptors.

Where does this data come from?

All data for 2-chloro-N-[5-[3-(2-fluorophenyl)-1-methylpyrazol-5-yl]-2-pyridinyl]benzamide;2-chloro-N-[5-[3-(furan-2-yl)-1-methylpyrazol-5-yl]-2-pyridinyl]benzamide;2,6-difluoro-N-[5-[3-(2-fluorophenyl)-1-methylpyrazol-5-yl]-2-pyridinyl]benzamide;2-fluoro-N-[5-[3-(2-fluorophenyl)-1-methylpyrazol-5-yl]-2-pyridinyl]benzamide;N-[5-[3-(2-fluorophenyl)-1-methylpyrazol-5-yl]-2-pyridinyl]-4-methyl-1,2-thiazole-5-carboxamide;N-[5-[3-(2-fluorophenyl)-1-methylpyrazol-5-yl]-2-pyridinyl]-3-methylthiophene-2-carboxamide is sourced from PubChem (CID 159231908), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).