ethyl 4-[5-phenyl-4-(pyridin-2-ylmethylamino)quinazolin-2-yl]-1,3-thiazole-2-carboxylate;bis(4-[5-phenyl-4-(pyridin-2-ylmethylamino)quinazolin-2-yl]-1,3-thiazole-2-carboxamide)

C74H57N17O4S3 — CID 159244141

IUPACethyl 4-[5-phenyl-4-(pyridin-2-ylmethylamino)quinazolin-2-yl]-1,3-thiazole-2-carboxylate;bis(4-[5-phenyl-4-(pyridin-2-ylmethylamino)quinazolin-2-yl]-1,3-thiazole-2-carboxamide)
SMILESCCOC(=O)c1nc(-c2nc(NCc3ccccn3)c3c(-c4ccccc4)cccc3n2)cs1.NC(=O)c1nc(-c2nc(NCc3ccccn3)c3c(-c4ccccc4)cccc3n2)cs1.NC(=O)c1nc(-c2nc(NCc3ccccn3)c3c(-c4ccccc4)cccc3n2)cs1
InChIInChI=1S/C26H21N5O2S.2C24H18N6OS/c1-2-33-26(32)25-30-21(16-34-25)23-29-20-13-8-12-19(17-9-4-3-5-10-17)22(20)24(31-23)28-15-18-11-6-7-14-27-18;2*25-21(31)24-29-19(14-32-24)22-28-18-11-6-10-17(15-7-2-1-3-8-15)20(18)23(30-22)27-13-16-9-4-5-12-26-16/h3-14,16H,2,15H2,1H3,(H,28,29,31);2*1-12,14H,13H2,(H2,25,31)(H,27,28,30)
InChIKeyKULSEKDRRPDXBO-UHFFFAOYSA-N
MW1344.59 g/mol
LogP14.66
Rot. Bonds19

About ethyl 4-[5-phenyl-4-(pyridin-2-ylmethylamino)quinazolin-2-yl]-1,3-thiazole-2-carboxylate;bis(4-[5-phenyl-4-(pyridin-2-ylmethylamino)quinazolin-2-yl]-1,3-thiazole-2-carboxamide)

ethyl 4-[5-phenyl-4-(pyridin-2-ylmethylamino)quinazolin-2-yl]-1,3-thiazole-2-carboxylate;bis(4-[5-phenyl-4-(pyridin-2-ylmethylamino)quinazolin-2-yl]-1,3-thiazole-2-carboxamide) (PubChem CID 159244141) has the molecular formula C74H57N17O4S3 and a molecular weight of 1344.59 g/mol. Its IUPAC name is ethyl 4-[5-phenyl-4-(pyridin-2-ylmethylamino)quinazolin-2-yl]-1,3-thiazole-2-carboxylate;bis(4-[5-phenyl-4-(pyridin-2-ylmethylamino)quinazolin-2-yl]-1,3-thiazole-2-carboxamide).

Molecular Properties

Compound Nameethyl 4-[5-phenyl-4-(pyridin-2-ylmethylamino)quinazolin-2-yl]-1,3-thiazole-2-carboxylate;bis(4-[5-phenyl-4-(pyridin-2-ylmethylamino)quinazolin-2-yl]-1,3-thiazole-2-carboxamide)
PubChem CID159244141
Molecular FormulaC74H57N17O4S3
Molecular Weight1344.59 g/mol
Exact Mass1343.39
IUPAC Nameethyl 4-[5-phenyl-4-(pyridin-2-ylmethylamino)quinazolin-2-yl]-1,3-thiazole-2-carboxylate;bis(4-[5-phenyl-4-(pyridin-2-ylmethylamino)quinazolin-2-yl]-1,3-thiazole-2-carboxamide)
SMILESCCOC(=O)c1nc(-c2nc(NCc3ccccn3)c3c(-c4ccccc4)cccc3n2)cs1.NC(=O)c1nc(-c2nc(NCc3ccccn3)c3c(-c4ccccc4)cccc3n2)cs1.NC(=O)c1nc(-c2nc(NCc3ccccn3)c3c(-c4ccccc4)cccc3n2)cs1
InChIInChI=1S/C26H21N5O2S.2C24H18N6OS/c1-2-33-26(32)25-30-21(16-34-25)23-29-20-13-8-12-19(17-9-4-3-5-10-17)22(20)24(31-23)28-15-18-11-6-7-14-27-18;2*25-21(31)24-29-19(14-32-24)22-28-18-11-6-10-17(15-7-2-1-3-8-15)20(18)23(30-22)27-13-16-9-4-5-12-26-16/h3-14,16H,2,15H2,1H3,(H,28,29,31);2*1-12,14H,13H2,(H2,25,31)(H,27,28,30)
InChIKeyKULSEKDRRPDXBO-UHFFFAOYSA-N
XLogP14.66
TPSA303.25 Ų
H-Bond Donors5
H-Bond Acceptors22
Rotatable Bonds19
Heavy Atoms98
Complexity

Lipinski Rule of Five

3 violations

RuleValue
MW ≤ 5001344.59
LogP ≤ 514.66
H-Bond Donors ≤ 55
H-Bond Acceptors ≤ 1022

Analyze ethyl 4-[5-phenyl-4-(pyridin-2-ylmethylamino)quinazolin-2-yl]-1,3-thiazole-2-carboxylate;bis(4-[5-phenyl-4-(pyridin-2-ylmethylamino)quinazolin-2-yl]-1,3-thiazole-2-carboxamide) with MolForge

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Frequently Asked Questions

What is the IUPAC name of ethyl 4-[5-phenyl-4-(pyridin-2-ylmethylamino)quinazolin-2-yl]-1,3-thiazole-2-carboxylate;bis(4-[5-phenyl-4-(pyridin-2-ylmethylamino)quinazolin-2-yl]-1,3-thiazole-2-carboxamide)?
The IUPAC name of ethyl 4-[5-phenyl-4-(pyridin-2-ylmethylamino)quinazolin-2-yl]-1,3-thiazole-2-carboxylate;bis(4-[5-phenyl-4-(pyridin-2-ylmethylamino)quinazolin-2-yl]-1,3-thiazole-2-carboxamide) (CID 159244141) is ethyl 4-[5-phenyl-4-(pyridin-2-ylmethylamino)quinazolin-2-yl]-1,3-thiazole-2-carboxylate;bis(4-[5-phenyl-4-(pyridin-2-ylmethylamino)quinazolin-2-yl]-1,3-thiazole-2-carboxamide).
What is the SMILES notation for ethyl 4-[5-phenyl-4-(pyridin-2-ylmethylamino)quinazolin-2-yl]-1,3-thiazole-2-carboxylate;bis(4-[5-phenyl-4-(pyridin-2-ylmethylamino)quinazolin-2-yl]-1,3-thiazole-2-carboxamide)?
The canonical SMILES for ethyl 4-[5-phenyl-4-(pyridin-2-ylmethylamino)quinazolin-2-yl]-1,3-thiazole-2-carboxylate;bis(4-[5-phenyl-4-(pyridin-2-ylmethylamino)quinazolin-2-yl]-1,3-thiazole-2-carboxamide) is CCOC(=O)c1nc(-c2nc(NCc3ccccn3)c3c(-c4ccccc4)cccc3n2)cs1.NC(=O)c1nc(-c2nc(NCc3ccccn3)c3c(-c4ccccc4)cccc3n2)cs1.NC(=O)c1nc(-c2nc(NCc3ccccn3)c3c(-c4ccccc4)cccc3n2)cs1.
What is the InChIKey of ethyl 4-[5-phenyl-4-(pyridin-2-ylmethylamino)quinazolin-2-yl]-1,3-thiazole-2-carboxylate;bis(4-[5-phenyl-4-(pyridin-2-ylmethylamino)quinazolin-2-yl]-1,3-thiazole-2-carboxamide)?
The InChIKey is KULSEKDRRPDXBO-UHFFFAOYSA-N. The full InChI is InChI=1S/C26H21N5O2S.2C24H18N6OS/c1-2-33-26(32)25-30-21(16-34-25)23-29-20-13-8-12-19(17-9-4-3-5-10-17)22(20)24(31-23)28-15-18-11-6-7-14-27-18;2*25-21(31)24-29-19(14-32-24)22-28-18-11-6-10-17(15-7-2-1-3-8-15)20(18)23(30-22)27-13-16-9-4-5-12-26-16/h3-14,16H,2,15H2,1H3,(H,28,29,31);2*1-12,14H,13H2,(H2,25,31)(H,27,28,30).
What are the key properties of ethyl 4-[5-phenyl-4-(pyridin-2-ylmethylamino)quinazolin-2-yl]-1,3-thiazole-2-carboxylate;bis(4-[5-phenyl-4-(pyridin-2-ylmethylamino)quinazolin-2-yl]-1,3-thiazole-2-carboxamide)?
ethyl 4-[5-phenyl-4-(pyridin-2-ylmethylamino)quinazolin-2-yl]-1,3-thiazole-2-carboxylate;bis(4-[5-phenyl-4-(pyridin-2-ylmethylamino)quinazolin-2-yl]-1,3-thiazole-2-carboxamide) has a molecular weight of 1344.59 g/mol, XLogP of 14.66, 19 rotatable bonds, 5 hydrogen bond donors, and 22 hydrogen bond acceptors.
Where does this data come from?
All data for ethyl 4-[5-phenyl-4-(pyridin-2-ylmethylamino)quinazolin-2-yl]-1,3-thiazole-2-carboxylate;bis(4-[5-phenyl-4-(pyridin-2-ylmethylamino)quinazolin-2-yl]-1,3-thiazole-2-carboxamide) is sourced from PubChem (CID 159244141), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).