1-[(3R)-3-[[2-[(2-cyclobutyl-1,3-dihydroisoindol-5-yl)amino]-5-fluoropyrimidin-4-yl]amino]piperidin-1-yl]prop-2-en-1-one;1-[(3R)-3-[[5-fluoro-2-[(2-methyl-1,3-dihydroisoindol-5-yl)amino]pyrimidin-4-yl]amino]piperidin-1-yl]prop-2-en-1-one;1-[(3R)-3-[[5-fluoro-2-[[2-[(1-methylpiperidin-4-yl)methyl]-1,3-dihydroisoindol-5-yl]amino]pyrimidin-4-yl]amino]piperidin-1-yl]prop-2-en-1-one;1-[(3R)-3-[[5-fluoro-2-[[2-(oxan-4-ylmethyl)-1,3-dihydroisoindol-5-yl]amino]pyrimidin-4-yl]amino]piperidin-1-yl]prop-2-en-1-one;1-[(3R)-3-[[5-fluoro-2-[(2-propan-2-yl-1,3-dihydroisoindol-5-yl)amino]pyrimidin-4-yl]amino]piperidin-1-yl]prop-2-en-1-one;2-[5-[[5-fluoro-4-[[(3R)-1-prop-2-enoylpiperidin-3-yl]amino]pyrimidin-2-yl]amino]-1,3-dihydroisoindol-2-yl]acetamide

C143H178F6N38O8 — CID 159264659

About 1-[(3R)-3-[[2-[(2-cyclobutyl-1,3-dihydroisoindol-5-yl)amino]-5-fluoropyrimidin-4-yl]amino]piperidin-1-yl]prop-2-en-1-one;1-[(3R)-3-[[5-fluoro-2-[(2-methyl-1,3-dihydroisoindol-5-yl)amino]pyrimidin-4-yl]amino]piperidin-1-yl]prop-2-en-1-one;1-[(3R)-3-[[5-fluoro-2-[[2-[(1-methylpiperidin-4-yl)methyl]-1,3-dihydroisoindol-5-yl]amino]pyrimidin-4-yl]amino]piperidin-1-yl]prop-2-en-1-one;1-[(3R)-3-[[5-fluoro-2-[[2-(oxan-4-ylmethyl)-1,3-dihydroisoindol-5-yl]amino]pyrimidin-4-yl]amino]piperidin-1-yl]prop-2-en-1-one;1-[(3R)-3-[[5-fluoro-2-[(2-propan-2-yl-1,3-dihydroisoindol-5-yl)amino]pyrimidin-4-yl]amino]piperidin-1-yl]prop-2-en-1-one;2-[5-[[5-fluoro-4-[[(3R)-1-prop-2-enoylpiperidin-3-yl]amino]pyrimidin-2-yl]amino]-1,3-dihydroisoindol-2-yl]acetamide

1-[(3R)-3-[[2-[(2-cyclobutyl-1,3-dihydroisoindol-5-yl)amino]-5-fluoropyrimidin-4-yl]amino]piperidin-1-yl]prop-2-en-1-one;1-[(3R)-3-[[5-fluoro-2-[(2-methyl-1,3-dihydroisoindol-5-yl)amino]pyrimidin-4-yl]amino]piperidin-1-yl]prop-2-en-1-one;1-[(3R)-3-[[5-fluoro-2-[[2-[(1-methylpiperidin-4-yl)methyl]-1,3-dihydroisoindol-5-yl]amino]pyrimidin-4-yl]amino]piperidin-1-yl]prop-2-en-1-one;1-[(3R)-3-[[5-fluoro-2-[[2-(oxan-4-ylmethyl)-1,3-dihydroisoindol-5-yl]amino]pyrimidin-4-yl]amino]piperidin-1-yl]prop-2-en-1-one;1-[(3R)-3-[[5-fluoro-2-[(2-propan-2-yl-1,3-dihydroisoindol-5-yl)amino]pyrimidin-4-yl]amino]piperidin-1-yl]prop-2-en-1-one;2-[5-[[5-fluoro-4-[[(3R)-1-prop-2-enoylpiperidin-3-yl]amino]pyrimidin-2-yl]amino]-1,3-dihydroisoindol-2-yl]acetamide (PubChem CID 159264659) has the molecular formula C143H178F6N38O8 and a molecular weight of 2671.24 g/mol. Its IUPAC name is 1-[(3R)-3-[[2-[(2-cyclobutyl-1,3-dihydroisoindol-5-yl)amino]-5-fluoropyrimidin-4-yl]amino]piperidin-1-yl]prop-2-en-1-one;1-[(3R)-3-[[5-fluoro-2-[(2-methyl-1,3-dihydroisoindol-5-yl)amino]pyrimidin-4-yl]amino]piperidin-1-yl]prop-2-en-1-one;1-[(3R)-3-[[5-fluoro-2-[[2-[(1-methylpiperidin-4-yl)methyl]-1,3-dihydroisoindol-5-yl]amino]pyrimidin-4-yl]amino]piperidin-1-yl]prop-2-en-1-one;1-[(3R)-3-[[5-fluoro-2-[[2-(oxan-4-ylmethyl)-1,3-dihydroisoindol-5-yl]amino]pyrimidin-4-yl]amino]piperidin-1-yl]prop-2-en-1-one;1-[(3R)-3-[[5-fluoro-2-[(2-propan-2-yl-1,3-dihydroisoindol-5-yl)amino]pyrimidin-4-yl]amino]piperidin-1-yl]prop-2-en-1-one;2-[5-[[5-fluoro-4-[[(3R)-1-prop-2-enoylpiperidin-3-yl]amino]pyrimidin-2-yl]amino]-1,3-dihydroisoindol-2-yl]acetamide.

Molecular Properties

• Compound Name: 1-[(3R)-3-[[2-[(2-cyclobutyl-1,3-dihydroisoindol-5-yl)amino]-5-fluoropyrimidin-4-yl]amino]piperidin-1-yl]prop-2-en-1-one;1-[(3R)-3-[[5-fluoro-2-[(2-methyl-1,3-dihydroisoindol-5-yl)amino]pyrimidin-4-yl]amino]piperidin-1-yl]prop-2-en-1-one;1-[(3R)-3-[[5-fluoro-2-[[2-[(1-methylpiperidin-4-yl)methyl]-1,3-dihydroisoindol-5-yl]amino]pyrimidin-4-yl]amino]piperidin-1-yl]prop-2-en-1-one;1-[(3R)-3-[[5-fluoro-2-[[2-(oxan-4-ylmethyl)-1,3-dihydroisoindol-5-yl]amino]pyrimidin-4-yl]amino]piperidin-1-yl]prop-2-en-1-one;1-[(3R)-3-[[5-fluoro-2-[(2-propan-2-yl-1,3-dihydroisoindol-5-yl)amino]pyrimidin-4-yl]amino]piperidin-1-yl]prop-2-en-1-one;2-[5-[[5-fluoro-4-[[(3R)-1-prop-2-enoylpiperidin-3-yl]amino]pyrimidin-2-yl]amino]-1,3-dihydroisoindol-2-yl]acetamide
• PubChem CID: 159264659
• Molecular Formula: C143H178F6N38O8
• Molecular Weight: 2671.24 g/mol
• Exact Mass: 2669.46
• IUPAC Name: 1-[(3R)-3-[[2-[(2-cyclobutyl-1,3-dihydroisoindol-5-yl)amino]-5-fluoropyrimidin-4-yl]amino]piperidin-1-yl]prop-2-en-1-one;1-[(3R)-3-[[5-fluoro-2-[(2-methyl-1,3-dihydroisoindol-5-yl)amino]pyrimidin-4-yl]amino]piperidin-1-yl]prop-2-en-1-one;1-[(3R)-3-[[5-fluoro-2-[[2-[(1-methylpiperidin-4-yl)methyl]-1,3-dihydroisoindol-5-yl]amino]pyrimidin-4-yl]amino]piperidin-1-yl]prop-2-en-1-one;1-[(3R)-3-[[5-fluoro-2-[[2-(oxan-4-ylmethyl)-1,3-dihydroisoindol-5-yl]amino]pyrimidin-4-yl]amino]piperidin-1-yl]prop-2-en-1-one;1-[(3R)-3-[[5-fluoro-2-[(2-propan-2-yl-1,3-dihydroisoindol-5-yl)amino]pyrimidin-4-yl]amino]piperidin-1-yl]prop-2-en-1-one;2-[5-[[5-fluoro-4-[[(3R)-1-prop-2-enoylpiperidin-3-yl]amino]pyrimidin-2-yl]amino]-1,3-dihydroisoindol-2-yl]acetamide
• SMILES: C=CC(=O)N1CCC[C@@H](Nc2nc(Nc3ccc4c(c3)CN(C(C)C)C4)ncc2F)C1.C=CC(=O)N1CCC[C@@H](Nc2nc(Nc3ccc4c(c3)CN(C)C4)ncc2F)C1.C=CC(=O)N1CCC[C@@H](Nc2nc(Nc3ccc4c(c3)CN(C3CCC3)C4)ncc2F)C1.C=CC(=O)N1CCC[C@@H](Nc2nc(Nc3ccc4c(c3)CN(CC(N)=O)C4)ncc2F)C1.C=CC(=O)N1CCC[C@@H](Nc2nc(Nc3ccc4c(c3)CN(CC3CCN(C)CC3)C4)ncc2F)C1.C=CC(=O)N1CCC[C@@H](Nc2nc(Nc3ccc4c(c3)CN(CC3CCOCC3)C4)ncc2F)C1
• InChI: InChI=1S/C27H36FN7O.C26H33FN6O2.C24H29FN6O.C23H29FN6O.C22H26FN7O2.C21H25FN6O/c1-3-25(36)35-10-4-5-23(18-35)30-26-24(28)14-29-27(32-26)31-22-7-6-20-16-34(17-21(20)13-22)15-19-8-11-33(2)12-9-19;1-2-24(34)33-9-3-4-22(17-33)29-25-23(27)13-28-26(31-25)30-21-6-5-19-15-32(16-20(19)12-21)14-18-7-10-35-11-8-18;1-2-22(32)30-10-4-5-19(15-30)27-23-21(25)12-26-24(29-23)28-18-9-8-16-13-31(14-17(16)11-18)20-6-3-7-20;1-4-21(31)29-9-5-6-19(14-29)26-22-20(24)11-25-23(28-22)27-18-8-7-16-12-30(15(2)3)13-17(16)10-18;1-2-20(32)30-7-3-4-17(12-30)26-21-18(23)9-25-22(28-21)27-16-6-5-14-10-29(13-19(24)31)11-15(14)8-16;1-3-19(29)28-8-4-5-17(13-28)24-20-18(22)10-23-21(26-20)25-16-7-6-14-11-27(2)12-15(14)9-16/h3,6-7,13-14,19,23H,1,4-5,8-12,15-18H2,2H3,(H2,29,30,31,32);2,5-6,12-13,18,22H,1,3-4,7-11,14-17H2,(H2,28,29,30,31);2,8-9,11-12,19-20H,1,3-7,10,13-15H2,(H2,26,27,28,29);4,7-8,10-11,15,19H,1,5-6,9,12-14H2,2-3H3,(H2,25,26,27,28);2,5-6,8-9,17H,1,3-4,7,10-13H2,(H2,24,31)(H2,25,26,27,28);3,6-7,9-10,17H,1,4-5,8,11-13H2,2H3,(H2,23,24,25,26)/t23-;22-;2*19-;2*17-/m111111/s1
• InChIKey: KWYICRVKACNLEK-ZCKAXOEYSA-N
• XLogP: 19.43
• TPSA: 495.90 Ų
• H-Bond Donors: 13
• H-Bond Acceptors: 39
• Rotatable Bonds: 38
• Heavy Atoms: 195
• Complexity: —

Lipinski Rule of Five

4 violations

Rule	Value
MW ≤ 500	2671.24
LogP ≤ 5	19.43
H-Bond Donors ≤ 5	13
H-Bond Acceptors ≤ 10	39

Computed Properties (RDKit)

• Structural Alerts: {'alert_name': 'Michael_acceptor_1', 'substructure': 'N/A'}

Frequently Asked Questions

What is the IUPAC name of 1-[(3R)-3-[[2-[(2-cyclobutyl-1,3-dihydroisoindol-5-yl)amino]-5-fluoropyrimidin-4-yl]amino]piperidin-1-yl]prop-2-en-1-one;1-[(3R)-3-[[5-fluoro-2-[(2-methyl-1,3-dihydroisoindol-5-yl)amino]pyrimidin-4-yl]amino]piperidin-1-yl]prop-2-en-1-one;1-[(3R)-3-[[5-fluoro-2-[[2-[(1-methylpiperidin-4-yl)methyl]-1,3-dihydroisoindol-5-yl]amino]pyrimidin-4-yl]amino]piperidin-1-yl]prop-2-en-1-one;1-[(3R)-3-[[5-fluoro-2-[[2-(oxan-4-ylmethyl)-1,3-dihydroisoindol-5-yl]amino]pyrimidin-4-yl]amino]piperidin-1-yl]prop-2-en-1-one;1-[(3R)-3-[[5-fluoro-2-[(2-propan-2-yl-1,3-dihydroisoindol-5-yl)amino]pyrimidin-4-yl]amino]piperidin-1-yl]prop-2-en-1-one;2-[5-[[5-fluoro-4-[[(3R)-1-prop-2-enoylpiperidin-3-yl]amino]pyrimidin-2-yl]amino]-1,3-dihydroisoindol-2-yl]acetamide?

The IUPAC name of 1-[(3R)-3-[[2-[(2-cyclobutyl-1,3-dihydroisoindol-5-yl)amino]-5-fluoropyrimidin-4-yl]amino]piperidin-1-yl]prop-2-en-1-one;1-[(3R)-3-[[5-fluoro-2-[(2-methyl-1,3-dihydroisoindol-5-yl)amino]pyrimidin-4-yl]amino]piperidin-1-yl]prop-2-en-1-one;1-[(3R)-3-[[5-fluoro-2-[[2-[(1-methylpiperidin-4-yl)methyl]-1,3-dihydroisoindol-5-yl]amino]pyrimidin-4-yl]amino]piperidin-1-yl]prop-2-en-1-one;1-[(3R)-3-[[5-fluoro-2-[[2-(oxan-4-ylmethyl)-1,3-dihydroisoindol-5-yl]amino]pyrimidin-4-yl]amino]piperidin-1-yl]prop-2-en-1-one;1-[(3R)-3-[[5-fluoro-2-[(2-propan-2-yl-1,3-dihydroisoindol-5-yl)amino]pyrimidin-4-yl]amino]piperidin-1-yl]prop-2-en-1-one;2-[5-[[5-fluoro-4-[[(3R)-1-prop-2-enoylpiperidin-3-yl]amino]pyrimidin-2-yl]amino]-1,3-dihydroisoindol-2-yl]acetamide (CID 159264659) is 1-[(3R)-3-[[2-[(2-cyclobutyl-1,3-dihydroisoindol-5-yl)amino]-5-fluoropyrimidin-4-yl]amino]piperidin-1-yl]prop-2-en-1-one;1-[(3R)-3-[[5-fluoro-2-[(2-methyl-1,3-dihydroisoindol-5-yl)amino]pyrimidin-4-yl]amino]piperidin-1-yl]prop-2-en-1-one;1-[(3R)-3-[[5-fluoro-2-[[2-[(1-methylpiperidin-4-yl)methyl]-1,3-dihydroisoindol-5-yl]amino]pyrimidin-4-yl]amino]piperidin-1-yl]prop-2-en-1-one;1-[(3R)-3-[[5-fluoro-2-[[2-(oxan-4-ylmethyl)-1,3-dihydroisoindol-5-yl]amino]pyrimidin-4-yl]amino]piperidin-1-yl]prop-2-en-1-one;1-[(3R)-3-[[5-fluoro-2-[(2-propan-2-yl-1,3-dihydroisoindol-5-yl)amino]pyrimidin-4-yl]amino]piperidin-1-yl]prop-2-en-1-one;2-[5-[[5-fluoro-4-[[(3R)-1-prop-2-enoylpiperidin-3-yl]amino]pyrimidin-2-yl]amino]-1,3-dihydroisoindol-2-yl]acetamide.

What is the SMILES notation for 1-[(3R)-3-[[2-[(2-cyclobutyl-1,3-dihydroisoindol-5-yl)amino]-5-fluoropyrimidin-4-yl]amino]piperidin-1-yl]prop-2-en-1-one;1-[(3R)-3-[[5-fluoro-2-[(2-methyl-1,3-dihydroisoindol-5-yl)amino]pyrimidin-4-yl]amino]piperidin-1-yl]prop-2-en-1-one;1-[(3R)-3-[[5-fluoro-2-[[2-[(1-methylpiperidin-4-yl)methyl]-1,3-dihydroisoindol-5-yl]amino]pyrimidin-4-yl]amino]piperidin-1-yl]prop-2-en-1-one;1-[(3R)-3-[[5-fluoro-2-[[2-(oxan-4-ylmethyl)-1,3-dihydroisoindol-5-yl]amino]pyrimidin-4-yl]amino]piperidin-1-yl]prop-2-en-1-one;1-[(3R)-3-[[5-fluoro-2-[(2-propan-2-yl-1,3-dihydroisoindol-5-yl)amino]pyrimidin-4-yl]amino]piperidin-1-yl]prop-2-en-1-one;2-[5-[[5-fluoro-4-[[(3R)-1-prop-2-enoylpiperidin-3-yl]amino]pyrimidin-2-yl]amino]-1,3-dihydroisoindol-2-yl]acetamide?

The canonical SMILES for 1-[(3R)-3-[[2-[(2-cyclobutyl-1,3-dihydroisoindol-5-yl)amino]-5-fluoropyrimidin-4-yl]amino]piperidin-1-yl]prop-2-en-1-one;1-[(3R)-3-[[5-fluoro-2-[(2-methyl-1,3-dihydroisoindol-5-yl)amino]pyrimidin-4-yl]amino]piperidin-1-yl]prop-2-en-1-one;1-[(3R)-3-[[5-fluoro-2-[[2-[(1-methylpiperidin-4-yl)methyl]-1,3-dihydroisoindol-5-yl]amino]pyrimidin-4-yl]amino]piperidin-1-yl]prop-2-en-1-one;1-[(3R)-3-[[5-fluoro-2-[[2-(oxan-4-ylmethyl)-1,3-dihydroisoindol-5-yl]amino]pyrimidin-4-yl]amino]piperidin-1-yl]prop-2-en-1-one;1-[(3R)-3-[[5-fluoro-2-[(2-propan-2-yl-1,3-dihydroisoindol-5-yl)amino]pyrimidin-4-yl]amino]piperidin-1-yl]prop-2-en-1-one;2-[5-[[5-fluoro-4-[[(3R)-1-prop-2-enoylpiperidin-3-yl]amino]pyrimidin-2-yl]amino]-1,3-dihydroisoindol-2-yl]acetamide is C=CC(=O)N1CCC[C@@H](Nc2nc(Nc3ccc4c(c3)CN(C(C)C)C4)ncc2F)C1.C=CC(=O)N1CCC[C@@H](Nc2nc(Nc3ccc4c(c3)CN(C)C4)ncc2F)C1.C=CC(=O)N1CCC[C@@H](Nc2nc(Nc3ccc4c(c3)CN(C3CCC3)C4)ncc2F)C1.C=CC(=O)N1CCC[C@@H](Nc2nc(Nc3ccc4c(c3)CN(CC(N)=O)C4)ncc2F)C1.C=CC(=O)N1CCC[C@@H](Nc2nc(Nc3ccc4c(c3)CN(CC3CCN(C)CC3)C4)ncc2F)C1.C=CC(=O)N1CCC[C@@H](Nc2nc(Nc3ccc4c(c3)CN(CC3CCOCC3)C4)ncc2F)C1.

What is the InChIKey of 1-[(3R)-3-[[2-[(2-cyclobutyl-1,3-dihydroisoindol-5-yl)amino]-5-fluoropyrimidin-4-yl]amino]piperidin-1-yl]prop-2-en-1-one;1-[(3R)-3-[[5-fluoro-2-[(2-methyl-1,3-dihydroisoindol-5-yl)amino]pyrimidin-4-yl]amino]piperidin-1-yl]prop-2-en-1-one;1-[(3R)-3-[[5-fluoro-2-[[2-[(1-methylpiperidin-4-yl)methyl]-1,3-dihydroisoindol-5-yl]amino]pyrimidin-4-yl]amino]piperidin-1-yl]prop-2-en-1-one;1-[(3R)-3-[[5-fluoro-2-[[2-(oxan-4-ylmethyl)-1,3-dihydroisoindol-5-yl]amino]pyrimidin-4-yl]amino]piperidin-1-yl]prop-2-en-1-one;1-[(3R)-3-[[5-fluoro-2-[(2-propan-2-yl-1,3-dihydroisoindol-5-yl)amino]pyrimidin-4-yl]amino]piperidin-1-yl]prop-2-en-1-one;2-[5-[[5-fluoro-4-[[(3R)-1-prop-2-enoylpiperidin-3-yl]amino]pyrimidin-2-yl]amino]-1,3-dihydroisoindol-2-yl]acetamide?

The InChIKey is KWYICRVKACNLEK-ZCKAXOEYSA-N. The full InChI is InChI=1S/C27H36FN7O.C26H33FN6O2.C24H29FN6O.C23H29FN6O.C22H26FN7O2.C21H25FN6O/c1-3-25(36)35-10-4-5-23(18-35)30-26-24(28)14-29-27(32-26)31-22-7-6-20-16-34(17-21(20)13-22)15-19-8-11-33(2)12-9-19;1-2-24(34)33-9-3-4-22(17-33)29-25-23(27)13-28-26(31-25)30-21-6-5-19-15-32(16-20(19)12-21)14-18-7-10-35-11-8-18;1-2-22(32)30-10-4-5-19(15-30)27-23-21(25)12-26-24(29-23)28-18-9-8-16-13-31(14-17(16)11-18)20-6-3-7-20;1-4-21(31)29-9-5-6-19(14-29)26-22-20(24)11-25-23(28-22)27-18-8-7-16-12-30(15(2)3)13-17(16)10-18;1-2-20(32)30-7-3-4-17(12-30)26-21-18(23)9-25-22(28-21)27-16-6-5-14-10-29(13-19(24)31)11-15(14)8-16;1-3-19(29)28-8-4-5-17(13-28)24-20-18(22)10-23-21(26-20)25-16-7-6-14-11-27(2)12-15(14)9-16/h3,6-7,13-14,19,23H,1,4-5,8-12,15-18H2,2H3,(H2,29,30,31,32);2,5-6,12-13,18,22H,1,3-4,7-11,14-17H2,(H2,28,29,30,31);2,8-9,11-12,19-20H,1,3-7,10,13-15H2,(H2,26,27,28,29);4,7-8,10-11,15,19H,1,5-6,9,12-14H2,2-3H3,(H2,25,26,27,28);2,5-6,8-9,17H,1,3-4,7,10-13H2,(H2,24,31)(H2,25,26,27,28);3,6-7,9-10,17H,1,4-5,8,11-13H2,2H3,(H2,23,24,25,26)/t23-;22-;2*19-;2*17-/m111111/s1.

What are the key properties of 1-[(3R)-3-[[2-[(2-cyclobutyl-1,3-dihydroisoindol-5-yl)amino]-5-fluoropyrimidin-4-yl]amino]piperidin-1-yl]prop-2-en-1-one;1-[(3R)-3-[[5-fluoro-2-[(2-methyl-1,3-dihydroisoindol-5-yl)amino]pyrimidin-4-yl]amino]piperidin-1-yl]prop-2-en-1-one;1-[(3R)-3-[[5-fluoro-2-[[2-[(1-methylpiperidin-4-yl)methyl]-1,3-dihydroisoindol-5-yl]amino]pyrimidin-4-yl]amino]piperidin-1-yl]prop-2-en-1-one;1-[(3R)-3-[[5-fluoro-2-[[2-(oxan-4-ylmethyl)-1,3-dihydroisoindol-5-yl]amino]pyrimidin-4-yl]amino]piperidin-1-yl]prop-2-en-1-one;1-[(3R)-3-[[5-fluoro-2-[(2-propan-2-yl-1,3-dihydroisoindol-5-yl)amino]pyrimidin-4-yl]amino]piperidin-1-yl]prop-2-en-1-one;2-[5-[[5-fluoro-4-[[(3R)-1-prop-2-enoylpiperidin-3-yl]amino]pyrimidin-2-yl]amino]-1,3-dihydroisoindol-2-yl]acetamide?

1-[(3R)-3-[[2-[(2-cyclobutyl-1,3-dihydroisoindol-5-yl)amino]-5-fluoropyrimidin-4-yl]amino]piperidin-1-yl]prop-2-en-1-one;1-[(3R)-3-[[5-fluoro-2-[(2-methyl-1,3-dihydroisoindol-5-yl)amino]pyrimidin-4-yl]amino]piperidin-1-yl]prop-2-en-1-one;1-[(3R)-3-[[5-fluoro-2-[[2-[(1-methylpiperidin-4-yl)methyl]-1,3-dihydroisoindol-5-yl]amino]pyrimidin-4-yl]amino]piperidin-1-yl]prop-2-en-1-one;1-[(3R)-3-[[5-fluoro-2-[[2-(oxan-4-ylmethyl)-1,3-dihydroisoindol-5-yl]amino]pyrimidin-4-yl]amino]piperidin-1-yl]prop-2-en-1-one;1-[(3R)-3-[[5-fluoro-2-[(2-propan-2-yl-1,3-dihydroisoindol-5-yl)amino]pyrimidin-4-yl]amino]piperidin-1-yl]prop-2-en-1-one;2-[5-[[5-fluoro-4-[[(3R)-1-prop-2-enoylpiperidin-3-yl]amino]pyrimidin-2-yl]amino]-1,3-dihydroisoindol-2-yl]acetamide has a molecular weight of 2671.24 g/mol, XLogP of 19.43, 38 rotatable bonds, 13 hydrogen bond donors, and 39 hydrogen bond acceptors.

Where does this data come from?

All data for 1-[(3R)-3-[[2-[(2-cyclobutyl-1,3-dihydroisoindol-5-yl)amino]-5-fluoropyrimidin-4-yl]amino]piperidin-1-yl]prop-2-en-1-one;1-[(3R)-3-[[5-fluoro-2-[(2-methyl-1,3-dihydroisoindol-5-yl)amino]pyrimidin-4-yl]amino]piperidin-1-yl]prop-2-en-1-one;1-[(3R)-3-[[5-fluoro-2-[[2-[(1-methylpiperidin-4-yl)methyl]-1,3-dihydroisoindol-5-yl]amino]pyrimidin-4-yl]amino]piperidin-1-yl]prop-2-en-1-one;1-[(3R)-3-[[5-fluoro-2-[[2-(oxan-4-ylmethyl)-1,3-dihydroisoindol-5-yl]amino]pyrimidin-4-yl]amino]piperidin-1-yl]prop-2-en-1-one;1-[(3R)-3-[[5-fluoro-2-[(2-propan-2-yl-1,3-dihydroisoindol-5-yl)amino]pyrimidin-4-yl]amino]piperidin-1-yl]prop-2-en-1-one;2-[5-[[5-fluoro-4-[[(3R)-1-prop-2-enoylpiperidin-3-yl]amino]pyrimidin-2-yl]amino]-1,3-dihydroisoindol-2-yl]acetamide is sourced from PubChem (CID 159264659), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).