6-[2-chloro-4-(5-methyl-4H-imidazol-2-yl)phenyl]-8-ethyl-2-[(6-piperazin-1-yl-3-pyridinyl)amino]pyrido[2,3-d]pyrimidin-7-one;6-[3-chloro-5-(5-methyl-4H-imidazol-2-yl)-2-pyridinyl]-8-ethyl-2-[4-(4-methylpiperazin-1-yl)anilino]pyrido[2,3-d]pyrimidin-7-one;6-[4-chloro-6-(5-methyl-4H-imidazol-2-yl)-3-pyridinyl]-8-ethyl-2-[4-(4-methylpiperazin-1-yl)anilino]pyrido[2,3-d]pyrimidin-7-one;8-ethyl-6-[6-(5-methyl-4H-imidazol-2-yl)-3-pyridinyl]-2-[4-(4-methylpiperazin-1-yl)anilino]pyrido[2,3-d]pyrimidin-7-one;6-[4-methyl-6-(2-methylpyrazol-3-yl)-3-pyridinyl]-2-[4-(piperidin-3-ylamino)anilino]-8-(1,3-thiazol-2-ylmethyl)pyrido[2,3-d]pyrimidin-7-one;6-[4-methyl-6-(1-methylpyrrol-2-yl)-3-pyridinyl]-2-[4-[(1-methylpiperidin-4-yl)amino]anilino]-8-(oxan-4-ylmethyl)pyrido[2,3-d]pyrimidin-7-one

C183H193Cl3N54O7S — CID 159265388

About 6-[2-chloro-4-(5-methyl-4H-imidazol-2-yl)phenyl]-8-ethyl-2-[(6-piperazin-1-yl-3-pyridinyl)amino]pyrido[2,3-d]pyrimidin-7-one;6-[3-chloro-5-(5-methyl-4H-imidazol-2-yl)-2-pyridinyl]-8-ethyl-2-[4-(4-methylpiperazin-1-yl)anilino]pyrido[2,3-d]pyrimidin-7-one;6-[4-chloro-6-(5-methyl-4H-imidazol-2-yl)-3-pyridinyl]-8-ethyl-2-[4-(4-methylpiperazin-1-yl)anilino]pyrido[2,3-d]pyrimidin-7-one;8-ethyl-6-[6-(5-methyl-4H-imidazol-2-yl)-3-pyridinyl]-2-[4-(4-methylpiperazin-1-yl)anilino]pyrido[2,3-d]pyrimidin-7-one;6-[4-methyl-6-(2-methylpyrazol-3-yl)-3-pyridinyl]-2-[4-(piperidin-3-ylamino)anilino]-8-(1,3-thiazol-2-ylmethyl)pyrido[2,3-d]pyrimidin-7-one;6-[4-methyl-6-(1-methylpyrrol-2-yl)-3-pyridinyl]-2-[4-[(1-methylpiperidin-4-yl)amino]anilino]-8-(oxan-4-ylmethyl)pyrido[2,3-d]pyrimidin-7-one

6-[2-chloro-4-(5-methyl-4H-imidazol-2-yl)phenyl]-8-ethyl-2-[(6-piperazin-1-yl-3-pyridinyl)amino]pyrido[2,3-d]pyrimidin-7-one;6-[3-chloro-5-(5-methyl-4H-imidazol-2-yl)-2-pyridinyl]-8-ethyl-2-[4-(4-methylpiperazin-1-yl)anilino]pyrido[2,3-d]pyrimidin-7-one;6-[4-chloro-6-(5-methyl-4H-imidazol-2-yl)-3-pyridinyl]-8-ethyl-2-[4-(4-methylpiperazin-1-yl)anilino]pyrido[2,3-d]pyrimidin-7-one;8-ethyl-6-[6-(5-methyl-4H-imidazol-2-yl)-3-pyridinyl]-2-[4-(4-methylpiperazin-1-yl)anilino]pyrido[2,3-d]pyrimidin-7-one;6-[4-methyl-6-(2-methylpyrazol-3-yl)-3-pyridinyl]-2-[4-(piperidin-3-ylamino)anilino]-8-(1,3-thiazol-2-ylmethyl)pyrido[2,3-d]pyrimidin-7-one;6-[4-methyl-6-(1-methylpyrrol-2-yl)-3-pyridinyl]-2-[4-[(1-methylpiperidin-4-yl)amino]anilino]-8-(oxan-4-ylmethyl)pyrido[2,3-d]pyrimidin-7-one (PubChem CID 159265388) has the molecular formula C183H193Cl3N54O7S and a molecular weight of 3399.35 g/mol. Its IUPAC name is 6-[2-chloro-4-(5-methyl-4H-imidazol-2-yl)phenyl]-8-ethyl-2-[(6-piperazin-1-yl-3-pyridinyl)amino]pyrido[2,3-d]pyrimidin-7-one;6-[3-chloro-5-(5-methyl-4H-imidazol-2-yl)-2-pyridinyl]-8-ethyl-2-[4-(4-methylpiperazin-1-yl)anilino]pyrido[2,3-d]pyrimidin-7-one;6-[4-chloro-6-(5-methyl-4H-imidazol-2-yl)-3-pyridinyl]-8-ethyl-2-[4-(4-methylpiperazin-1-yl)anilino]pyrido[2,3-d]pyrimidin-7-one;8-ethyl-6-[6-(5-methyl-4H-imidazol-2-yl)-3-pyridinyl]-2-[4-(4-methylpiperazin-1-yl)anilino]pyrido[2,3-d]pyrimidin-7-one;6-[4-methyl-6-(2-methylpyrazol-3-yl)-3-pyridinyl]-2-[4-(piperidin-3-ylamino)anilino]-8-(1,3-thiazol-2-ylmethyl)pyrido[2,3-d]pyrimidin-7-one;6-[4-methyl-6-(1-methylpyrrol-2-yl)-3-pyridinyl]-2-[4-[(1-methylpiperidin-4-yl)amino]anilino]-8-(oxan-4-ylmethyl)pyrido[2,3-d]pyrimidin-7-one.

Molecular Properties

• Compound Name: 6-[2-chloro-4-(5-methyl-4H-imidazol-2-yl)phenyl]-8-ethyl-2-[(6-piperazin-1-yl-3-pyridinyl)amino]pyrido[2,3-d]pyrimidin-7-one;6-[3-chloro-5-(5-methyl-4H-imidazol-2-yl)-2-pyridinyl]-8-ethyl-2-[4-(4-methylpiperazin-1-yl)anilino]pyrido[2,3-d]pyrimidin-7-one;6-[4-chloro-6-(5-methyl-4H-imidazol-2-yl)-3-pyridinyl]-8-ethyl-2-[4-(4-methylpiperazin-1-yl)anilino]pyrido[2,3-d]pyrimidin-7-one;8-ethyl-6-[6-(5-methyl-4H-imidazol-2-yl)-3-pyridinyl]-2-[4-(4-methylpiperazin-1-yl)anilino]pyrido[2,3-d]pyrimidin-7-one;6-[4-methyl-6-(2-methylpyrazol-3-yl)-3-pyridinyl]-2-[4-(piperidin-3-ylamino)anilino]-8-(1,3-thiazol-2-ylmethyl)pyrido[2,3-d]pyrimidin-7-one;6-[4-methyl-6-(1-methylpyrrol-2-yl)-3-pyridinyl]-2-[4-[(1-methylpiperidin-4-yl)amino]anilino]-8-(oxan-4-ylmethyl)pyrido[2,3-d]pyrimidin-7-one
• PubChem CID: 159265388
• Molecular Formula: C183H193Cl3N54O7S
• Molecular Weight: 3399.35 g/mol
• Exact Mass: 3395.52
• IUPAC Name: 6-[2-chloro-4-(5-methyl-4H-imidazol-2-yl)phenyl]-8-ethyl-2-[(6-piperazin-1-yl-3-pyridinyl)amino]pyrido[2,3-d]pyrimidin-7-one;6-[3-chloro-5-(5-methyl-4H-imidazol-2-yl)-2-pyridinyl]-8-ethyl-2-[4-(4-methylpiperazin-1-yl)anilino]pyrido[2,3-d]pyrimidin-7-one;6-[4-chloro-6-(5-methyl-4H-imidazol-2-yl)-3-pyridinyl]-8-ethyl-2-[4-(4-methylpiperazin-1-yl)anilino]pyrido[2,3-d]pyrimidin-7-one;8-ethyl-6-[6-(5-methyl-4H-imidazol-2-yl)-3-pyridinyl]-2-[4-(4-methylpiperazin-1-yl)anilino]pyrido[2,3-d]pyrimidin-7-one;6-[4-methyl-6-(2-methylpyrazol-3-yl)-3-pyridinyl]-2-[4-(piperidin-3-ylamino)anilino]-8-(1,3-thiazol-2-ylmethyl)pyrido[2,3-d]pyrimidin-7-one;6-[4-methyl-6-(1-methylpyrrol-2-yl)-3-pyridinyl]-2-[4-[(1-methylpiperidin-4-yl)amino]anilino]-8-(oxan-4-ylmethyl)pyrido[2,3-d]pyrimidin-7-one
• SMILES: CCn1c(=O)c(-c2ccc(C3=NCC(C)=N3)cc2Cl)cc2cnc(Nc3ccc(N4CCNCC4)nc3)nc21.CCn1c(=O)c(-c2ccc(C3=NCC(C)=N3)nc2)cc2cnc(Nc3ccc(N4CCN(C)CC4)cc3)nc21.CCn1c(=O)c(-c2cnc(C3=NCC(C)=N3)cc2Cl)cc2cnc(Nc3ccc(N4CCN(C)CC4)cc3)nc21.CCn1c(=O)c(-c2ncc(C3=NCC(C)=N3)cc2Cl)cc2cnc(Nc3ccc(N4CCN(C)CC4)cc3)nc21.Cc1cc(-c2cccn2C)ncc1-c1cc2cnc(Nc3ccc(NC4CCN(C)CC4)cc3)nc2n(CC2CCOCC2)c1=O.Cc1cc(-c2ccnn2C)ncc1-c1cc2cnc(Nc3ccc(NC4CCCNC4)cc3)nc2n(Cc2nccs2)c1=O
• InChI: InChI=1S/C36H42N8O2.C32H32N10OS.2C29H30ClN9O.C29H31N9O.C28H28ClN9O/c1-24-19-32(33-5-4-14-43(33)3)37-22-31(24)30-20-26-21-38-36(41-34(26)44(35(30)45)23-25-12-17-46-18-13-25)40-28-8-6-27(7-9-28)39-29-10-15-42(2)16-11-29;1-20-14-27(28-9-11-37-41(28)2)35-18-26(20)25-15-21-16-36-32(40-30(21)42(31(25)43)19-29-34-12-13-44-29)39-23-7-5-22(6-8-23)38-24-4-3-10-33-17-24;1-4-39-27-20(13-23(28(39)40)25-24(30)14-19(16-31-25)26-32-15-18(2)34-26)17-33-29(36-27)35-21-5-7-22(8-6-21)38-11-9-37(3)10-12-38;1-4-39-27-19(13-22(28(39)40)23-17-31-25(14-24(23)30)26-32-15-18(2)34-26)16-33-29(36-27)35-20-5-7-21(8-6-20)38-11-9-37(3)10-12-38;1-4-38-27-21(15-24(28(38)39)20-5-10-25(30-17-20)26-31-16-19(2)33-26)18-32-29(35-27)34-22-6-8-23(9-7-22)37-13-11-36(3)12-14-37;1-3-38-26-19(12-22(27(38)39)21-6-4-18(13-23(21)29)25-32-14-17(2)34-25)15-33-28(36-26)35-20-5-7-24(31-16-20)37-10-8-30-9-11-37/h4-9,14,19-22,25,29,39H,10-13,15-18,23H2,1-3H3,(H,38,40,41);5-9,11-16,18,24,33,38H,3-4,10,17,19H2,1-2H3,(H,36,39,40);2*5-8,13-14,16-17H,4,9-12,15H2,1-3H3,(H,33,35,36);5-10,15,17-18H,4,11-14,16H2,1-3H3,(H,32,34,35);4-7,12-13,15-16,30H,3,8-11,14H2,1-2H3,(H,33,35,36)
• InChIKey: KXANHLJHWVPWPI-UHFFFAOYSA-N
• XLogP: 26.80
• TPSA: 653.99 Ų
• H-Bond Donors: 10
• H-Bond Acceptors: 62
• Rotatable Bonds: 40
• Heavy Atoms: 248
• Complexity: —

Lipinski Rule of Five

4 violations

Rule	Value
MW ≤ 500	3399.35
LogP ≤ 5	26.80
H-Bond Donors ≤ 5	10
H-Bond Acceptors ≤ 10	62

Computed Properties (RDKit)

• Structural Alerts: {'alert_name': 'anil_di_alk_A(478)', 'substructure': 'N/A'}

Frequently Asked Questions

What is the IUPAC name of 6-[2-chloro-4-(5-methyl-4H-imidazol-2-yl)phenyl]-8-ethyl-2-[(6-piperazin-1-yl-3-pyridinyl)amino]pyrido[2,3-d]pyrimidin-7-one;6-[3-chloro-5-(5-methyl-4H-imidazol-2-yl)-2-pyridinyl]-8-ethyl-2-[4-(4-methylpiperazin-1-yl)anilino]pyrido[2,3-d]pyrimidin-7-one;6-[4-chloro-6-(5-methyl-4H-imidazol-2-yl)-3-pyridinyl]-8-ethyl-2-[4-(4-methylpiperazin-1-yl)anilino]pyrido[2,3-d]pyrimidin-7-one;8-ethyl-6-[6-(5-methyl-4H-imidazol-2-yl)-3-pyridinyl]-2-[4-(4-methylpiperazin-1-yl)anilino]pyrido[2,3-d]pyrimidin-7-one;6-[4-methyl-6-(2-methylpyrazol-3-yl)-3-pyridinyl]-2-[4-(piperidin-3-ylamino)anilino]-8-(1,3-thiazol-2-ylmethyl)pyrido[2,3-d]pyrimidin-7-one;6-[4-methyl-6-(1-methylpyrrol-2-yl)-3-pyridinyl]-2-[4-[(1-methylpiperidin-4-yl)amino]anilino]-8-(oxan-4-ylmethyl)pyrido[2,3-d]pyrimidin-7-one?

The IUPAC name of 6-[2-chloro-4-(5-methyl-4H-imidazol-2-yl)phenyl]-8-ethyl-2-[(6-piperazin-1-yl-3-pyridinyl)amino]pyrido[2,3-d]pyrimidin-7-one;6-[3-chloro-5-(5-methyl-4H-imidazol-2-yl)-2-pyridinyl]-8-ethyl-2-[4-(4-methylpiperazin-1-yl)anilino]pyrido[2,3-d]pyrimidin-7-one;6-[4-chloro-6-(5-methyl-4H-imidazol-2-yl)-3-pyridinyl]-8-ethyl-2-[4-(4-methylpiperazin-1-yl)anilino]pyrido[2,3-d]pyrimidin-7-one;8-ethyl-6-[6-(5-methyl-4H-imidazol-2-yl)-3-pyridinyl]-2-[4-(4-methylpiperazin-1-yl)anilino]pyrido[2,3-d]pyrimidin-7-one;6-[4-methyl-6-(2-methylpyrazol-3-yl)-3-pyridinyl]-2-[4-(piperidin-3-ylamino)anilino]-8-(1,3-thiazol-2-ylmethyl)pyrido[2,3-d]pyrimidin-7-one;6-[4-methyl-6-(1-methylpyrrol-2-yl)-3-pyridinyl]-2-[4-[(1-methylpiperidin-4-yl)amino]anilino]-8-(oxan-4-ylmethyl)pyrido[2,3-d]pyrimidin-7-one (CID 159265388) is 6-[2-chloro-4-(5-methyl-4H-imidazol-2-yl)phenyl]-8-ethyl-2-[(6-piperazin-1-yl-3-pyridinyl)amino]pyrido[2,3-d]pyrimidin-7-one;6-[3-chloro-5-(5-methyl-4H-imidazol-2-yl)-2-pyridinyl]-8-ethyl-2-[4-(4-methylpiperazin-1-yl)anilino]pyrido[2,3-d]pyrimidin-7-one;6-[4-chloro-6-(5-methyl-4H-imidazol-2-yl)-3-pyridinyl]-8-ethyl-2-[4-(4-methylpiperazin-1-yl)anilino]pyrido[2,3-d]pyrimidin-7-one;8-ethyl-6-[6-(5-methyl-4H-imidazol-2-yl)-3-pyridinyl]-2-[4-(4-methylpiperazin-1-yl)anilino]pyrido[2,3-d]pyrimidin-7-one;6-[4-methyl-6-(2-methylpyrazol-3-yl)-3-pyridinyl]-2-[4-(piperidin-3-ylamino)anilino]-8-(1,3-thiazol-2-ylmethyl)pyrido[2,3-d]pyrimidin-7-one;6-[4-methyl-6-(1-methylpyrrol-2-yl)-3-pyridinyl]-2-[4-[(1-methylpiperidin-4-yl)amino]anilino]-8-(oxan-4-ylmethyl)pyrido[2,3-d]pyrimidin-7-one.

What is the SMILES notation for 6-[2-chloro-4-(5-methyl-4H-imidazol-2-yl)phenyl]-8-ethyl-2-[(6-piperazin-1-yl-3-pyridinyl)amino]pyrido[2,3-d]pyrimidin-7-one;6-[3-chloro-5-(5-methyl-4H-imidazol-2-yl)-2-pyridinyl]-8-ethyl-2-[4-(4-methylpiperazin-1-yl)anilino]pyrido[2,3-d]pyrimidin-7-one;6-[4-chloro-6-(5-methyl-4H-imidazol-2-yl)-3-pyridinyl]-8-ethyl-2-[4-(4-methylpiperazin-1-yl)anilino]pyrido[2,3-d]pyrimidin-7-one;8-ethyl-6-[6-(5-methyl-4H-imidazol-2-yl)-3-pyridinyl]-2-[4-(4-methylpiperazin-1-yl)anilino]pyrido[2,3-d]pyrimidin-7-one;6-[4-methyl-6-(2-methylpyrazol-3-yl)-3-pyridinyl]-2-[4-(piperidin-3-ylamino)anilino]-8-(1,3-thiazol-2-ylmethyl)pyrido[2,3-d]pyrimidin-7-one;6-[4-methyl-6-(1-methylpyrrol-2-yl)-3-pyridinyl]-2-[4-[(1-methylpiperidin-4-yl)amino]anilino]-8-(oxan-4-ylmethyl)pyrido[2,3-d]pyrimidin-7-one?

The canonical SMILES for 6-[2-chloro-4-(5-methyl-4H-imidazol-2-yl)phenyl]-8-ethyl-2-[(6-piperazin-1-yl-3-pyridinyl)amino]pyrido[2,3-d]pyrimidin-7-one;6-[3-chloro-5-(5-methyl-4H-imidazol-2-yl)-2-pyridinyl]-8-ethyl-2-[4-(4-methylpiperazin-1-yl)anilino]pyrido[2,3-d]pyrimidin-7-one;6-[4-chloro-6-(5-methyl-4H-imidazol-2-yl)-3-pyridinyl]-8-ethyl-2-[4-(4-methylpiperazin-1-yl)anilino]pyrido[2,3-d]pyrimidin-7-one;8-ethyl-6-[6-(5-methyl-4H-imidazol-2-yl)-3-pyridinyl]-2-[4-(4-methylpiperazin-1-yl)anilino]pyrido[2,3-d]pyrimidin-7-one;6-[4-methyl-6-(2-methylpyrazol-3-yl)-3-pyridinyl]-2-[4-(piperidin-3-ylamino)anilino]-8-(1,3-thiazol-2-ylmethyl)pyrido[2,3-d]pyrimidin-7-one;6-[4-methyl-6-(1-methylpyrrol-2-yl)-3-pyridinyl]-2-[4-[(1-methylpiperidin-4-yl)amino]anilino]-8-(oxan-4-ylmethyl)pyrido[2,3-d]pyrimidin-7-one is CCn1c(=O)c(-c2ccc(C3=NCC(C)=N3)cc2Cl)cc2cnc(Nc3ccc(N4CCNCC4)nc3)nc21.CCn1c(=O)c(-c2ccc(C3=NCC(C)=N3)nc2)cc2cnc(Nc3ccc(N4CCN(C)CC4)cc3)nc21.CCn1c(=O)c(-c2cnc(C3=NCC(C)=N3)cc2Cl)cc2cnc(Nc3ccc(N4CCN(C)CC4)cc3)nc21.CCn1c(=O)c(-c2ncc(C3=NCC(C)=N3)cc2Cl)cc2cnc(Nc3ccc(N4CCN(C)CC4)cc3)nc21.Cc1cc(-c2cccn2C)ncc1-c1cc2cnc(Nc3ccc(NC4CCN(C)CC4)cc3)nc2n(CC2CCOCC2)c1=O.Cc1cc(-c2ccnn2C)ncc1-c1cc2cnc(Nc3ccc(NC4CCCNC4)cc3)nc2n(Cc2nccs2)c1=O.

What is the InChIKey of 6-[2-chloro-4-(5-methyl-4H-imidazol-2-yl)phenyl]-8-ethyl-2-[(6-piperazin-1-yl-3-pyridinyl)amino]pyrido[2,3-d]pyrimidin-7-one;6-[3-chloro-5-(5-methyl-4H-imidazol-2-yl)-2-pyridinyl]-8-ethyl-2-[4-(4-methylpiperazin-1-yl)anilino]pyrido[2,3-d]pyrimidin-7-one;6-[4-chloro-6-(5-methyl-4H-imidazol-2-yl)-3-pyridinyl]-8-ethyl-2-[4-(4-methylpiperazin-1-yl)anilino]pyrido[2,3-d]pyrimidin-7-one;8-ethyl-6-[6-(5-methyl-4H-imidazol-2-yl)-3-pyridinyl]-2-[4-(4-methylpiperazin-1-yl)anilino]pyrido[2,3-d]pyrimidin-7-one;6-[4-methyl-6-(2-methylpyrazol-3-yl)-3-pyridinyl]-2-[4-(piperidin-3-ylamino)anilino]-8-(1,3-thiazol-2-ylmethyl)pyrido[2,3-d]pyrimidin-7-one;6-[4-methyl-6-(1-methylpyrrol-2-yl)-3-pyridinyl]-2-[4-[(1-methylpiperidin-4-yl)amino]anilino]-8-(oxan-4-ylmethyl)pyrido[2,3-d]pyrimidin-7-one?

The InChIKey is KXANHLJHWVPWPI-UHFFFAOYSA-N. The full InChI is InChI=1S/C36H42N8O2.C32H32N10OS.2C29H30ClN9O.C29H31N9O.C28H28ClN9O/c1-24-19-32(33-5-4-14-43(33)3)37-22-31(24)30-20-26-21-38-36(41-34(26)44(35(30)45)23-25-12-17-46-18-13-25)40-28-8-6-27(7-9-28)39-29-10-15-42(2)16-11-29;1-20-14-27(28-9-11-37-41(28)2)35-18-26(20)25-15-21-16-36-32(40-30(21)42(31(25)43)19-29-34-12-13-44-29)39-23-7-5-22(6-8-23)38-24-4-3-10-33-17-24;1-4-39-27-20(13-23(28(39)40)25-24(30)14-19(16-31-25)26-32-15-18(2)34-26)17-33-29(36-27)35-21-5-7-22(8-6-21)38-11-9-37(3)10-12-38;1-4-39-27-19(13-22(28(39)40)23-17-31-25(14-24(23)30)26-32-15-18(2)34-26)16-33-29(36-27)35-20-5-7-21(8-6-20)38-11-9-37(3)10-12-38;1-4-38-27-21(15-24(28(38)39)20-5-10-25(30-17-20)26-31-16-19(2)33-26)18-32-29(35-27)34-22-6-8-23(9-7-22)37-13-11-36(3)12-14-37;1-3-38-26-19(12-22(27(38)39)21-6-4-18(13-23(21)29)25-32-14-17(2)34-25)15-33-28(36-26)35-20-5-7-24(31-16-20)37-10-8-30-9-11-37/h4-9,14,19-22,25,29,39H,10-13,15-18,23H2,1-3H3,(H,38,40,41);5-9,11-16,18,24,33,38H,3-4,10,17,19H2,1-2H3,(H,36,39,40);2*5-8,13-14,16-17H,4,9-12,15H2,1-3H3,(H,33,35,36);5-10,15,17-18H,4,11-14,16H2,1-3H3,(H,32,34,35);4-7,12-13,15-16,30H,3,8-11,14H2,1-2H3,(H,33,35,36).

What are the key properties of 6-[2-chloro-4-(5-methyl-4H-imidazol-2-yl)phenyl]-8-ethyl-2-[(6-piperazin-1-yl-3-pyridinyl)amino]pyrido[2,3-d]pyrimidin-7-one;6-[3-chloro-5-(5-methyl-4H-imidazol-2-yl)-2-pyridinyl]-8-ethyl-2-[4-(4-methylpiperazin-1-yl)anilino]pyrido[2,3-d]pyrimidin-7-one;6-[4-chloro-6-(5-methyl-4H-imidazol-2-yl)-3-pyridinyl]-8-ethyl-2-[4-(4-methylpiperazin-1-yl)anilino]pyrido[2,3-d]pyrimidin-7-one;8-ethyl-6-[6-(5-methyl-4H-imidazol-2-yl)-3-pyridinyl]-2-[4-(4-methylpiperazin-1-yl)anilino]pyrido[2,3-d]pyrimidin-7-one;6-[4-methyl-6-(2-methylpyrazol-3-yl)-3-pyridinyl]-2-[4-(piperidin-3-ylamino)anilino]-8-(1,3-thiazol-2-ylmethyl)pyrido[2,3-d]pyrimidin-7-one;6-[4-methyl-6-(1-methylpyrrol-2-yl)-3-pyridinyl]-2-[4-[(1-methylpiperidin-4-yl)amino]anilino]-8-(oxan-4-ylmethyl)pyrido[2,3-d]pyrimidin-7-one?

6-[2-chloro-4-(5-methyl-4H-imidazol-2-yl)phenyl]-8-ethyl-2-[(6-piperazin-1-yl-3-pyridinyl)amino]pyrido[2,3-d]pyrimidin-7-one;6-[3-chloro-5-(5-methyl-4H-imidazol-2-yl)-2-pyridinyl]-8-ethyl-2-[4-(4-methylpiperazin-1-yl)anilino]pyrido[2,3-d]pyrimidin-7-one;6-[4-chloro-6-(5-methyl-4H-imidazol-2-yl)-3-pyridinyl]-8-ethyl-2-[4-(4-methylpiperazin-1-yl)anilino]pyrido[2,3-d]pyrimidin-7-one;8-ethyl-6-[6-(5-methyl-4H-imidazol-2-yl)-3-pyridinyl]-2-[4-(4-methylpiperazin-1-yl)anilino]pyrido[2,3-d]pyrimidin-7-one;6-[4-methyl-6-(2-methylpyrazol-3-yl)-3-pyridinyl]-2-[4-(piperidin-3-ylamino)anilino]-8-(1,3-thiazol-2-ylmethyl)pyrido[2,3-d]pyrimidin-7-one;6-[4-methyl-6-(1-methylpyrrol-2-yl)-3-pyridinyl]-2-[4-[(1-methylpiperidin-4-yl)amino]anilino]-8-(oxan-4-ylmethyl)pyrido[2,3-d]pyrimidin-7-one has a molecular weight of 3399.35 g/mol, XLogP of 26.80, 40 rotatable bonds, 10 hydrogen bond donors, and 62 hydrogen bond acceptors.

Where does this data come from?

All data for 6-[2-chloro-4-(5-methyl-4H-imidazol-2-yl)phenyl]-8-ethyl-2-[(6-piperazin-1-yl-3-pyridinyl)amino]pyrido[2,3-d]pyrimidin-7-one;6-[3-chloro-5-(5-methyl-4H-imidazol-2-yl)-2-pyridinyl]-8-ethyl-2-[4-(4-methylpiperazin-1-yl)anilino]pyrido[2,3-d]pyrimidin-7-one;6-[4-chloro-6-(5-methyl-4H-imidazol-2-yl)-3-pyridinyl]-8-ethyl-2-[4-(4-methylpiperazin-1-yl)anilino]pyrido[2,3-d]pyrimidin-7-one;8-ethyl-6-[6-(5-methyl-4H-imidazol-2-yl)-3-pyridinyl]-2-[4-(4-methylpiperazin-1-yl)anilino]pyrido[2,3-d]pyrimidin-7-one;6-[4-methyl-6-(2-methylpyrazol-3-yl)-3-pyridinyl]-2-[4-(piperidin-3-ylamino)anilino]-8-(1,3-thiazol-2-ylmethyl)pyrido[2,3-d]pyrimidin-7-one;6-[4-methyl-6-(1-methylpyrrol-2-yl)-3-pyridinyl]-2-[4-[(1-methylpiperidin-4-yl)amino]anilino]-8-(oxan-4-ylmethyl)pyrido[2,3-d]pyrimidin-7-one is sourced from PubChem (CID 159265388), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).