(2R,3R)-4-[(2R)-2-(2-amino-1,3-thiazol-4-yl)pyrrolidin-1-yl]-N-[[4-[(2-chlorophenyl)methyl]thiophen-2-yl]methyl]-2,3-dihydroxy-4-oxobutanamide;(2R,3R)-4-[(2R)-2-(4-tert-butyl-1,3-thiazol-2-yl)pyrrolidin-1-yl]-N-[[4-[(2-chlorophenyl)methyl]thiophen-2-yl]methyl]-2,3-dihydroxy-4-oxobutanamide;(2R,3R)-N-[[4-[(5-chloro-2-methylbenzimidazol-1-yl)methyl]-1,3-thiazol-2-yl]methyl]-4-[2-[3-(dimethylamino)phenyl]pyrrolidin-1-yl]-2,3-dihydroxy-4-oxobutanamide;(2R,3R)-N-[[4-[(2-chlorophenyl)methyl]thiophen-2-yl]methyl]-4-[(2R)-2-(5,6-dihydro-4H-cyclopenta[d][1,3]thiazol-2-yl)pyrrolidin-1-yl]-2,3-dihydroxy-4-oxobutanamide;(2R,3R)-N-[[4-[(2-chlorophenyl)methyl]thiophen-2-yl]methyl]-2,3-dihydroxy-4-[(2R)-2-(4-methyl-1,3-thiazol-2-yl)pyrrolidin-1-yl]-4-oxobutanamide;(2R,3R)-N-[[4-[(2-chlorophenyl)methyl]thiophen-2-yl]methyl]-2,3-dihydroxy-4-oxo-4-[(2R)-2-[4-(trifluoromethyl)-1,3-thiazol-2-yl]pyrrolidin-1-yl]butanamide;(2R,3R)-4-[(2R)-2-(5,6-dihydro-4H-cyclopenta[d][1,3]thiazol-2-yl)pyrrolidin-1-yl]-2,3-dihydroxy-4-oxo-N-(2-thiophen-2-ylethyl)butanamide;(2R,3R)-2,3-dihydroxy-4-[2-(1H-imidazol-2-yl)pyrrolidin-1-yl]-N-[[4-[(2-methylphenyl)methyl]-1,3-thiazol-2-yl]methyl]-4-oxobutanamide;(2R,3R)-2,3-dihydroxy-4-[2-(1H-imidazol-2-yl)pyrrolidin-1-yl]-4-oxo-N-(2-thiophen-2-ylethyl)butanamide;(2R,3R)-2,3-dihydroxy-4-[(2R)-2-(4-methyl-1,3-thiazol-2-yl)pyrrolidin-1-yl]-4-oxo-N-(2-thiophen-2-ylethyl)butanamide;(2R,3R)-2,3-dihydroxy-4-oxo-N-(2-thiophen-2-ylethyl)-4-[(2R)-2-[4-(trifluoromethyl)-1,3-thiazol-2-yl]pyrrolidin-1-yl]butanamide;ethyl 2-[(2R)-1-[(2R,3R)-4-[[4-[(2-chlorophenyl)methyl]thiophen-2-yl]methylamino]-2,3-dihydroxy-4-oxobutanoyl]pyrrolidin-2-yl]-1,3-thiazole-4-carboxylate

C275H312Cl7F6N43O50S21 — CID 159286767

About (2R,3R)-4-[(2R)-2-(2-amino-1,3-thiazol-4-yl)pyrrolidin-1-yl]-N-[[4-[(2-chlorophenyl)methyl]thiophen-2-yl]methyl]-2,3-dihydroxy-4-oxobutanamide;(2R,3R)-4-[(2R)-2-(4-tert-butyl-1,3-thiazol-2-yl)pyrrolidin-1-yl]-N-[[4-[(2-chlorophenyl)methyl]thiophen-2-yl]methyl]-2,3-dihydroxy-4-oxobutanamide;(2R,3R)-N-[[4-[(5-chloro-2-methylbenzimidazol-1-yl)methyl]-1,3-thiazol-2-yl]methyl]-4-[2-[3-(dimethylamino)phenyl]pyrrolidin-1-yl]-2,3-dihydroxy-4-oxobutanamide;(2R,3R)-N-[[4-[(2-chlorophenyl)methyl]thiophen-2-yl]methyl]-4-[(2R)-2-(5,6-dihydro-4H-cyclopenta[d][1,3]thiazol-2-yl)pyrrolidin-1-yl]-2,3-dihydroxy-4-oxobutanamide;(2R,3R)-N-[[4-[(2-chlorophenyl)methyl]thiophen-2-yl]methyl]-2,3-dihydroxy-4-[(2R)-2-(4-methyl-1,3-thiazol-2-yl)pyrrolidin-1-yl]-4-oxobutanamide;(2R,3R)-N-[[4-[(2-chlorophenyl)methyl]thiophen-2-yl]methyl]-2,3-dihydroxy-4-oxo-4-[(2R)-2-[4-(trifluoromethyl)-1,3-thiazol-2-yl]pyrrolidin-1-yl]butanamide;(2R,3R)-4-[(2R)-2-(5,6-dihydro-4H-cyclopenta[d][1,3]thiazol-2-yl)pyrrolidin-1-yl]-2,3-dihydroxy-4-oxo-N-(2-thiophen-2-ylethyl)butanamide;(2R,3R)-2,3-dihydroxy-4-[2-(1H-imidazol-2-yl)pyrrolidin-1-yl]-N-[[4-[(2-methylphenyl)methyl]-1,3-thiazol-2-yl]methyl]-4-oxobutanamide;(2R,3R)-2,3-dihydroxy-4-[2-(1H-imidazol-2-yl)pyrrolidin-1-yl]-4-oxo-N-(2-thiophen-2-ylethyl)butanamide;(2R,3R)-2,3-dihydroxy-4-[(2R)-2-(4-methyl-1,3-thiazol-2-yl)pyrrolidin-1-yl]-4-oxo-N-(2-thiophen-2-ylethyl)butanamide;(2R,3R)-2,3-dihydroxy-4-oxo-N-(2-thiophen-2-ylethyl)-4-[(2R)-2-[4-(trifluoromethyl)-1,3-thiazol-2-yl]pyrrolidin-1-yl]butanamide;ethyl 2-[(2R)-1-[(2R,3R)-4-[[4-[(2-chlorophenyl)methyl]thiophen-2-yl]methylamino]-2,3-dihydroxy-4-oxobutanoyl]pyrrolidin-2-yl]-1,3-thiazole-4-carboxylate

(2R,3R)-4-[(2R)-2-(2-amino-1,3-thiazol-4-yl)pyrrolidin-1-yl]-N-[[4-[(2-chlorophenyl)methyl]thiophen-2-yl]methyl]-2,3-dihydroxy-4-oxobutanamide;(2R,3R)-4-[(2R)-2-(4-tert-butyl-1,3-thiazol-2-yl)pyrrolidin-1-yl]-N-[[4-[(2-chlorophenyl)methyl]thiophen-2-yl]methyl]-2,3-dihydroxy-4-oxobutanamide;(2R,3R)-N-[[4-[(5-chloro-2-methylbenzimidazol-1-yl)methyl]-1,3-thiazol-2-yl]methyl]-4-[2-[3-(dimethylamino)phenyl]pyrrolidin-1-yl]-2,3-dihydroxy-4-oxobutanamide;(2R,3R)-N-[[4-[(2-chlorophenyl)methyl]thiophen-2-yl]methyl]-4-[(2R)-2-(5,6-dihydro-4H-cyclopenta[d][1,3]thiazol-2-yl)pyrrolidin-1-yl]-2,3-dihydroxy-4-oxobutanamide;(2R,3R)-N-[[4-[(2-chlorophenyl)methyl]thiophen-2-yl]methyl]-2,3-dihydroxy-4-[(2R)-2-(4-methyl-1,3-thiazol-2-yl)pyrrolidin-1-yl]-4-oxobutanamide;(2R,3R)-N-[[4-[(2-chlorophenyl)methyl]thiophen-2-yl]methyl]-2,3-dihydroxy-4-oxo-4-[(2R)-2-[4-(trifluoromethyl)-1,3-thiazol-2-yl]pyrrolidin-1-yl]butanamide;(2R,3R)-4-[(2R)-2-(5,6-dihydro-4H-cyclopenta[d][1,3]thiazol-2-yl)pyrrolidin-1-yl]-2,3-dihydroxy-4-oxo-N-(2-thiophen-2-ylethyl)butanamide;(2R,3R)-2,3-dihydroxy-4-[2-(1H-imidazol-2-yl)pyrrolidin-1-yl]-N-[[4-[(2-methylphenyl)methyl]-1,3-thiazol-2-yl]methyl]-4-oxobutanamide;(2R,3R)-2,3-dihydroxy-4-[2-(1H-imidazol-2-yl)pyrrolidin-1-yl]-4-oxo-N-(2-thiophen-2-ylethyl)butanamide;(2R,3R)-2,3-dihydroxy-4-[(2R)-2-(4-methyl-1,3-thiazol-2-yl)pyrrolidin-1-yl]-4-oxo-N-(2-thiophen-2-ylethyl)butanamide;(2R,3R)-2,3-dihydroxy-4-oxo-N-(2-thiophen-2-ylethyl)-4-[(2R)-2-[4-(trifluoromethyl)-1,3-thiazol-2-yl]pyrrolidin-1-yl]butanamide;ethyl 2-[(2R)-1-[(2R,3R)-4-[[4-[(2-chlorophenyl)methyl]thiophen-2-yl]methylamino]-2,3-dihydroxy-4-oxobutanoyl]pyrrolidin-2-yl]-1,3-thiazole-4-carboxylate (PubChem CID 159286767) has the molecular formula C275H312Cl7F6N43O50S21 and a molecular weight of 6055.34 g/mol. Its IUPAC name is (2R,3R)-4-[(2R)-2-(2-amino-1,3-thiazol-4-yl)pyrrolidin-1-yl]-N-[[4-[(2-chlorophenyl)methyl]thiophen-2-yl]methyl]-2,3-dihydroxy-4-oxobutanamide;(2R,3R)-4-[(2R)-2-(4-tert-butyl-1,3-thiazol-2-yl)pyrrolidin-1-yl]-N-[[4-[(2-chlorophenyl)methyl]thiophen-2-yl]methyl]-2,3-dihydroxy-4-oxobutanamide;(2R,3R)-N-[[4-[(5-chloro-2-methylbenzimidazol-1-yl)methyl]-1,3-thiazol-2-yl]methyl]-4-[2-[3-(dimethylamino)phenyl]pyrrolidin-1-yl]-2,3-dihydroxy-4-oxobutanamide;(2R,3R)-N-[[4-[(2-chlorophenyl)methyl]thiophen-2-yl]methyl]-4-[(2R)-2-(5,6-dihydro-4H-cyclopenta[d][1,3]thiazol-2-yl)pyrrolidin-1-yl]-2,3-dihydroxy-4-oxobutanamide;(2R,3R)-N-[[4-[(2-chlorophenyl)methyl]thiophen-2-yl]methyl]-2,3-dihydroxy-4-[(2R)-2-(4-methyl-1,3-thiazol-2-yl)pyrrolidin-1-yl]-4-oxobutanamide;(2R,3R)-N-[[4-[(2-chlorophenyl)methyl]thiophen-2-yl]methyl]-2,3-dihydroxy-4-oxo-4-[(2R)-2-[4-(trifluoromethyl)-1,3-thiazol-2-yl]pyrrolidin-1-yl]butanamide;(2R,3R)-4-[(2R)-2-(5,6-dihydro-4H-cyclopenta[d][1,3]thiazol-2-yl)pyrrolidin-1-yl]-2,3-dihydroxy-4-oxo-N-(2-thiophen-2-ylethyl)butanamide;(2R,3R)-2,3-dihydroxy-4-[2-(1H-imidazol-2-yl)pyrrolidin-1-yl]-N-[[4-[(2-methylphenyl)methyl]-1,3-thiazol-2-yl]methyl]-4-oxobutanamide;(2R,3R)-2,3-dihydroxy-4-[2-(1H-imidazol-2-yl)pyrrolidin-1-yl]-4-oxo-N-(2-thiophen-2-ylethyl)butanamide;(2R,3R)-2,3-dihydroxy-4-[(2R)-2-(4-methyl-1,3-thiazol-2-yl)pyrrolidin-1-yl]-4-oxo-N-(2-thiophen-2-ylethyl)butanamide;(2R,3R)-2,3-dihydroxy-4-oxo-N-(2-thiophen-2-ylethyl)-4-[(2R)-2-[4-(trifluoromethyl)-1,3-thiazol-2-yl]pyrrolidin-1-yl]butanamide;ethyl 2-[(2R)-1-[(2R,3R)-4-[[4-[(2-chlorophenyl)methyl]thiophen-2-yl]methylamino]-2,3-dihydroxy-4-oxobutanoyl]pyrrolidin-2-yl]-1,3-thiazole-4-carboxylate.

Molecular Properties

• Compound Name: (2R,3R)-4-[(2R)-2-(2-amino-1,3-thiazol-4-yl)pyrrolidin-1-yl]-N-[[4-[(2-chlorophenyl)methyl]thiophen-2-yl]methyl]-2,3-dihydroxy-4-oxobutanamide;(2R,3R)-4-[(2R)-2-(4-tert-butyl-1,3-thiazol-2-yl)pyrrolidin-1-yl]-N-[[4-[(2-chlorophenyl)methyl]thiophen-2-yl]methyl]-2,3-dihydroxy-4-oxobutanamide;(2R,3R)-N-[[4-[(5-chloro-2-methylbenzimidazol-1-yl)methyl]-1,3-thiazol-2-yl]methyl]-4-[2-[3-(dimethylamino)phenyl]pyrrolidin-1-yl]-2,3-dihydroxy-4-oxobutanamide;(2R,3R)-N-[[4-[(2-chlorophenyl)methyl]thiophen-2-yl]methyl]-4-[(2R)-2-(5,6-dihydro-4H-cyclopenta[d][1,3]thiazol-2-yl)pyrrolidin-1-yl]-2,3-dihydroxy-4-oxobutanamide;(2R,3R)-N-[[4-[(2-chlorophenyl)methyl]thiophen-2-yl]methyl]-2,3-dihydroxy-4-[(2R)-2-(4-methyl-1,3-thiazol-2-yl)pyrrolidin-1-yl]-4-oxobutanamide;(2R,3R)-N-[[4-[(2-chlorophenyl)methyl]thiophen-2-yl]methyl]-2,3-dihydroxy-4-oxo-4-[(2R)-2-[4-(trifluoromethyl)-1,3-thiazol-2-yl]pyrrolidin-1-yl]butanamide;(2R,3R)-4-[(2R)-2-(5,6-dihydro-4H-cyclopenta[d][1,3]thiazol-2-yl)pyrrolidin-1-yl]-2,3-dihydroxy-4-oxo-N-(2-thiophen-2-ylethyl)butanamide;(2R,3R)-2,3-dihydroxy-4-[2-(1H-imidazol-2-yl)pyrrolidin-1-yl]-N-[[4-[(2-methylphenyl)methyl]-1,3-thiazol-2-yl]methyl]-4-oxobutanamide;(2R,3R)-2,3-dihydroxy-4-[2-(1H-imidazol-2-yl)pyrrolidin-1-yl]-4-oxo-N-(2-thiophen-2-ylethyl)butanamide;(2R,3R)-2,3-dihydroxy-4-[(2R)-2-(4-methyl-1,3-thiazol-2-yl)pyrrolidin-1-yl]-4-oxo-N-(2-thiophen-2-ylethyl)butanamide;(2R,3R)-2,3-dihydroxy-4-oxo-N-(2-thiophen-2-ylethyl)-4-[(2R)-2-[4-(trifluoromethyl)-1,3-thiazol-2-yl]pyrrolidin-1-yl]butanamide;ethyl 2-[(2R)-1-[(2R,3R)-4-[[4-[(2-chlorophenyl)methyl]thiophen-2-yl]methylamino]-2,3-dihydroxy-4-oxobutanoyl]pyrrolidin-2-yl]-1,3-thiazole-4-carboxylate
• PubChem CID: 159286767
• Molecular Formula: C275H312Cl7F6N43O50S21
• Molecular Weight: 6055.34 g/mol
• Exact Mass: 6046.51
• IUPAC Name: (2R,3R)-4-[(2R)-2-(2-amino-1,3-thiazol-4-yl)pyrrolidin-1-yl]-N-[[4-[(2-chlorophenyl)methyl]thiophen-2-yl]methyl]-2,3-dihydroxy-4-oxobutanamide;(2R,3R)-4-[(2R)-2-(4-tert-butyl-1,3-thiazol-2-yl)pyrrolidin-1-yl]-N-[[4-[(2-chlorophenyl)methyl]thiophen-2-yl]methyl]-2,3-dihydroxy-4-oxobutanamide;(2R,3R)-N-[[4-[(5-chloro-2-methylbenzimidazol-1-yl)methyl]-1,3-thiazol-2-yl]methyl]-4-[2-[3-(dimethylamino)phenyl]pyrrolidin-1-yl]-2,3-dihydroxy-4-oxobutanamide;(2R,3R)-N-[[4-[(2-chlorophenyl)methyl]thiophen-2-yl]methyl]-4-[(2R)-2-(5,6-dihydro-4H-cyclopenta[d][1,3]thiazol-2-yl)pyrrolidin-1-yl]-2,3-dihydroxy-4-oxobutanamide;(2R,3R)-N-[[4-[(2-chlorophenyl)methyl]thiophen-2-yl]methyl]-2,3-dihydroxy-4-[(2R)-2-(4-methyl-1,3-thiazol-2-yl)pyrrolidin-1-yl]-4-oxobutanamide;(2R,3R)-N-[[4-[(2-chlorophenyl)methyl]thiophen-2-yl]methyl]-2,3-dihydroxy-4-oxo-4-[(2R)-2-[4-(trifluoromethyl)-1,3-thiazol-2-yl]pyrrolidin-1-yl]butanamide;(2R,3R)-4-[(2R)-2-(5,6-dihydro-4H-cyclopenta[d][1,3]thiazol-2-yl)pyrrolidin-1-yl]-2,3-dihydroxy-4-oxo-N-(2-thiophen-2-ylethyl)butanamide;(2R,3R)-2,3-dihydroxy-4-[2-(1H-imidazol-2-yl)pyrrolidin-1-yl]-N-[[4-[(2-methylphenyl)methyl]-1,3-thiazol-2-yl]methyl]-4-oxobutanamide;(2R,3R)-2,3-dihydroxy-4-[2-(1H-imidazol-2-yl)pyrrolidin-1-yl]-4-oxo-N-(2-thiophen-2-ylethyl)butanamide;(2R,3R)-2,3-dihydroxy-4-[(2R)-2-(4-methyl-1,3-thiazol-2-yl)pyrrolidin-1-yl]-4-oxo-N-(2-thiophen-2-ylethyl)butanamide;(2R,3R)-2,3-dihydroxy-4-oxo-N-(2-thiophen-2-ylethyl)-4-[(2R)-2-[4-(trifluoromethyl)-1,3-thiazol-2-yl]pyrrolidin-1-yl]butanamide;ethyl 2-[(2R)-1-[(2R,3R)-4-[[4-[(2-chlorophenyl)methyl]thiophen-2-yl]methylamino]-2,3-dihydroxy-4-oxobutanoyl]pyrrolidin-2-yl]-1,3-thiazole-4-carboxylate
• SMILES: CC(C)(C)c1csc([C@H]2CCCN2C(=O)[C@H](O)[C@@H](O)C(=O)NCc2cc(Cc3ccccc3Cl)cs2)n1.CCOC(=O)c1csc([C@H]2CCCN2C(=O)[C@H](O)[C@@H](O)C(=O)NCc2cc(Cc3ccccc3Cl)cs2)n1.Cc1ccccc1Cc1csc(CNC(=O)[C@H](O)[C@@H](O)C(=O)N2CCCC2c2ncc[nH]2)n1.Cc1csc([C@H]2CCCN2C(=O)[C@H](O)[C@@H](O)C(=O)NCCc2cccs2)n1.Cc1csc([C@H]2CCCN2C(=O)[C@H](O)[C@@H](O)C(=O)NCc2cc(Cc3ccccc3Cl)cs2)n1.Cc1nc2cc(Cl)ccc2n1Cc1csc(CNC(=O)[C@H](O)[C@@H](O)C(=O)N2CCCC2c2cccc(N(C)C)c2)n1.Nc1nc([C@H]2CCCN2C(=O)[C@H](O)[C@@H](O)C(=O)NCc2cc(Cc3ccccc3Cl)cs2)cs1.O=C(NCCc1cccs1)[C@H](O)[C@@H](O)C(=O)N1CCCC1c1ncc[nH]1.O=C(NCCc1cccs1)[C@H](O)[C@@H](O)C(=O)N1CCC[C@@H]1c1nc(C(F)(F)F)cs1.O=C(NCCc1cccs1)[C@H](O)[C@@H](O)C(=O)N1CCC[C@@H]1c1nc2c(s1)CCC2.O=C(NCc1cc(Cc2ccccc2Cl)cs1)[C@H](O)[C@@H](O)C(=O)N1CCC[C@@H]1c1nc(C(F)(F)F)cs1.O=C(NCc1cc(Cc2ccccc2Cl)cs1)[C@H](O)[C@@H](O)C(=O)N1CCC[C@@H]1c1nc2c(s1)CCC2
• InChI: InChI=1S/C29H33ClN6O4S.C27H32ClN3O4S2.C26H28ClN3O6S2.C26H28ClN3O4S2.C24H23ClF3N3O4S2.C24H26ClN3O4S2.C23H25ClN4O4S2.C23H27N5O4S.C20H25N3O4S2.C18H20F3N3O4S2.C18H23N3O4S2.C17H22N4O4S/c1-17-32-22-13-19(30)9-10-24(22)36(17)15-20-16-41-25(33-20)14-31-28(39)26(37)27(38)29(40)35-11-5-8-23(35)18-6-4-7-21(12-18)34(2)3;1-27(2,3)21-15-37-25(30-21)20-9-6-10-31(20)26(35)23(33)22(32)24(34)29-13-18-12-16(14-36-18)11-17-7-4-5-8-19(17)28;1-2-36-26(35)19-14-38-24(29-19)20-8-5-9-30(20)25(34)22(32)21(31)23(33)28-12-17-11-15(13-37-17)10-16-6-3-4-7-18(16)27;27-18-6-2-1-5-16(18)11-15-12-17(35-14-15)13-28-24(33)22(31)23(32)26(34)30-10-4-8-20(30)25-29-19-7-3-9-21(19)36-25;25-16-5-2-1-4-14(16)8-13-9-15(36-11-13)10-29-21(34)19(32)20(33)23(35)31-7-3-6-17(31)22-30-18(12-37-22)24(26,27)28;1-14-12-34-23(27-14)19-7-4-8-28(19)24(32)21(30)20(29)22(31)26-11-17-10-15(13-33-17)9-16-5-2-3-6-18(16)25;24-16-5-2-1-4-14(16)8-13-9-15(33-11-13)10-26-21(31)19(29)20(30)22(32)28-7-3-6-18(28)17-12-34-23(25)27-17;1-14-5-2-3-6-15(14)11-16-13-33-18(27-16)12-26-22(31)19(29)20(30)23(32)28-10-4-7-17(28)21-24-8-9-25-21;24-16(18(26)21-9-8-12-4-3-11-28-12)17(25)20(27)23-10-2-6-14(23)19-22-13-5-1-7-15(13)29-19;19-18(20,21)12-9-30-16(23-12)11-4-1-7-24(11)17(28)14(26)13(25)15(27)22-6-5-10-3-2-8-29-10;1-11-10-27-17(20-11)13-5-2-8-21(13)18(25)15(23)14(22)16(24)19-7-6-12-4-3-9-26-12;22-13(16(24)20-6-5-11-3-2-10-26-11)14(23)17(25)21-9-1-4-12(21)15-18-7-8-19-15/h4,6-7,9-10,12-13,16,23,26-27,37-38H,5,8,11,14-15H2,1-3H3,(H,31,39);4-5,7-8,12,14-15,20,22-23,32-33H,6,9-11,13H2,1-3H3,(H,29,34);3-4,6-7,11,13-14,20-22,31-32H,2,5,8-10,12H2,1H3,(H,28,33);1-2,5-6,12,14,20,22-23,31-32H,3-4,7-11,13H2,(H,28,33);1-2,4-5,9,11-12,17,19-20,32-33H,3,6-8,10H2,(H,29,34);2-3,5-6,10,12-13,19-21,29-30H,4,7-9,11H2,1H3,(H,26,31);1-2,4-5,9,11-12,18-20,29-30H,3,6-8,10H2,(H2,25,27)(H,26,31);2-3,5-6,8-9,13,17,19-20,29-30H,4,7,10-12H2,1H3,(H,24,25)(H,26,31);3-4,11,14,16-17,24-25H,1-2,5-10H2,(H,21,26);2-3,8-9,11,13-14,25-26H,1,4-7H2,(H,22,27);3-4,9-10,13-15,22-23H,2,5-8H2,1H3,(H,19,24);2-3,7-8,10,12-14,22-23H,1,4-6,9H2,(H,18,19)(H,20,24)/t23?,26-,27-;20-,22-,23-;20-,21-,22-;20-,22-,23-;17-,19-,20-;19-,20-,21-;18-,19-,20-;17?,19-,20-;14-,16-,17-;11-,13-,14-;13-,14-,15-;12?,13-,14-/m111111111111/s1
• InChIKey: KZPMAIHJPXBMSC-CBNSJUFKSA-N
• XLogP: 31.39
• TPSA: 1350.97 Ų
• H-Bond Donors: 39
• H-Bond Acceptors: 88
• Rotatable Bonds: 95
• Heavy Atoms: 402
• Complexity: —

Lipinski Rule of Five

4 violations

Rule	Value
MW ≤ 500	6055.34
LogP ≤ 5	31.39
H-Bond Donors ≤ 5	39
H-Bond Acceptors ≤ 10	88

Frequently Asked Questions

What is the IUPAC name of (2R,3R)-4-[(2R)-2-(2-amino-1,3-thiazol-4-yl)pyrrolidin-1-yl]-N-[[4-[(2-chlorophenyl)methyl]thiophen-2-yl]methyl]-2,3-dihydroxy-4-oxobutanamide;(2R,3R)-4-[(2R)-2-(4-tert-butyl-1,3-thiazol-2-yl)pyrrolidin-1-yl]-N-[[4-[(2-chlorophenyl)methyl]thiophen-2-yl]methyl]-2,3-dihydroxy-4-oxobutanamide;(2R,3R)-N-[[4-[(5-chloro-2-methylbenzimidazol-1-yl)methyl]-1,3-thiazol-2-yl]methyl]-4-[2-[3-(dimethylamino)phenyl]pyrrolidin-1-yl]-2,3-dihydroxy-4-oxobutanamide;(2R,3R)-N-[[4-[(2-chlorophenyl)methyl]thiophen-2-yl]methyl]-4-[(2R)-2-(5,6-dihydro-4H-cyclopenta[d][1,3]thiazol-2-yl)pyrrolidin-1-yl]-2,3-dihydroxy-4-oxobutanamide;(2R,3R)-N-[[4-[(2-chlorophenyl)methyl]thiophen-2-yl]methyl]-2,3-dihydroxy-4-[(2R)-2-(4-methyl-1,3-thiazol-2-yl)pyrrolidin-1-yl]-4-oxobutanamide;(2R,3R)-N-[[4-[(2-chlorophenyl)methyl]thiophen-2-yl]methyl]-2,3-dihydroxy-4-oxo-4-[(2R)-2-[4-(trifluoromethyl)-1,3-thiazol-2-yl]pyrrolidin-1-yl]butanamide;(2R,3R)-4-[(2R)-2-(5,6-dihydro-4H-cyclopenta[d][1,3]thiazol-2-yl)pyrrolidin-1-yl]-2,3-dihydroxy-4-oxo-N-(2-thiophen-2-ylethyl)butanamide;(2R,3R)-2,3-dihydroxy-4-[2-(1H-imidazol-2-yl)pyrrolidin-1-yl]-N-[[4-[(2-methylphenyl)methyl]-1,3-thiazol-2-yl]methyl]-4-oxobutanamide;(2R,3R)-2,3-dihydroxy-4-[2-(1H-imidazol-2-yl)pyrrolidin-1-yl]-4-oxo-N-(2-thiophen-2-ylethyl)butanamide;(2R,3R)-2,3-dihydroxy-4-[(2R)-2-(4-methyl-1,3-thiazol-2-yl)pyrrolidin-1-yl]-4-oxo-N-(2-thiophen-2-ylethyl)butanamide;(2R,3R)-2,3-dihydroxy-4-oxo-N-(2-thiophen-2-ylethyl)-4-[(2R)-2-[4-(trifluoromethyl)-1,3-thiazol-2-yl]pyrrolidin-1-yl]butanamide;ethyl 2-[(2R)-1-[(2R,3R)-4-[[4-[(2-chlorophenyl)methyl]thiophen-2-yl]methylamino]-2,3-dihydroxy-4-oxobutanoyl]pyrrolidin-2-yl]-1,3-thiazole-4-carboxylate?

The IUPAC name of (2R,3R)-4-[(2R)-2-(2-amino-1,3-thiazol-4-yl)pyrrolidin-1-yl]-N-[[4-[(2-chlorophenyl)methyl]thiophen-2-yl]methyl]-2,3-dihydroxy-4-oxobutanamide;(2R,3R)-4-[(2R)-2-(4-tert-butyl-1,3-thiazol-2-yl)pyrrolidin-1-yl]-N-[[4-[(2-chlorophenyl)methyl]thiophen-2-yl]methyl]-2,3-dihydroxy-4-oxobutanamide;(2R,3R)-N-[[4-[(5-chloro-2-methylbenzimidazol-1-yl)methyl]-1,3-thiazol-2-yl]methyl]-4-[2-[3-(dimethylamino)phenyl]pyrrolidin-1-yl]-2,3-dihydroxy-4-oxobutanamide;(2R,3R)-N-[[4-[(2-chlorophenyl)methyl]thiophen-2-yl]methyl]-4-[(2R)-2-(5,6-dihydro-4H-cyclopenta[d][1,3]thiazol-2-yl)pyrrolidin-1-yl]-2,3-dihydroxy-4-oxobutanamide;(2R,3R)-N-[[4-[(2-chlorophenyl)methyl]thiophen-2-yl]methyl]-2,3-dihydroxy-4-[(2R)-2-(4-methyl-1,3-thiazol-2-yl)pyrrolidin-1-yl]-4-oxobutanamide;(2R,3R)-N-[[4-[(2-chlorophenyl)methyl]thiophen-2-yl]methyl]-2,3-dihydroxy-4-oxo-4-[(2R)-2-[4-(trifluoromethyl)-1,3-thiazol-2-yl]pyrrolidin-1-yl]butanamide;(2R,3R)-4-[(2R)-2-(5,6-dihydro-4H-cyclopenta[d][1,3]thiazol-2-yl)pyrrolidin-1-yl]-2,3-dihydroxy-4-oxo-N-(2-thiophen-2-ylethyl)butanamide;(2R,3R)-2,3-dihydroxy-4-[2-(1H-imidazol-2-yl)pyrrolidin-1-yl]-N-[[4-[(2-methylphenyl)methyl]-1,3-thiazol-2-yl]methyl]-4-oxobutanamide;(2R,3R)-2,3-dihydroxy-4-[2-(1H-imidazol-2-yl)pyrrolidin-1-yl]-4-oxo-N-(2-thiophen-2-ylethyl)butanamide;(2R,3R)-2,3-dihydroxy-4-[(2R)-2-(4-methyl-1,3-thiazol-2-yl)pyrrolidin-1-yl]-4-oxo-N-(2-thiophen-2-ylethyl)butanamide;(2R,3R)-2,3-dihydroxy-4-oxo-N-(2-thiophen-2-ylethyl)-4-[(2R)-2-[4-(trifluoromethyl)-1,3-thiazol-2-yl]pyrrolidin-1-yl]butanamide;ethyl 2-[(2R)-1-[(2R,3R)-4-[[4-[(2-chlorophenyl)methyl]thiophen-2-yl]methylamino]-2,3-dihydroxy-4-oxobutanoyl]pyrrolidin-2-yl]-1,3-thiazole-4-carboxylate (CID 159286767) is (2R,3R)-4-[(2R)-2-(2-amino-1,3-thiazol-4-yl)pyrrolidin-1-yl]-N-[[4-[(2-chlorophenyl)methyl]thiophen-2-yl]methyl]-2,3-dihydroxy-4-oxobutanamide;(2R,3R)-4-[(2R)-2-(4-tert-butyl-1,3-thiazol-2-yl)pyrrolidin-1-yl]-N-[[4-[(2-chlorophenyl)methyl]thiophen-2-yl]methyl]-2,3-dihydroxy-4-oxobutanamide;(2R,3R)-N-[[4-[(5-chloro-2-methylbenzimidazol-1-yl)methyl]-1,3-thiazol-2-yl]methyl]-4-[2-[3-(dimethylamino)phenyl]pyrrolidin-1-yl]-2,3-dihydroxy-4-oxobutanamide;(2R,3R)-N-[[4-[(2-chlorophenyl)methyl]thiophen-2-yl]methyl]-4-[(2R)-2-(5,6-dihydro-4H-cyclopenta[d][1,3]thiazol-2-yl)pyrrolidin-1-yl]-2,3-dihydroxy-4-oxobutanamide;(2R,3R)-N-[[4-[(2-chlorophenyl)methyl]thiophen-2-yl]methyl]-2,3-dihydroxy-4-[(2R)-2-(4-methyl-1,3-thiazol-2-yl)pyrrolidin-1-yl]-4-oxobutanamide;(2R,3R)-N-[[4-[(2-chlorophenyl)methyl]thiophen-2-yl]methyl]-2,3-dihydroxy-4-oxo-4-[(2R)-2-[4-(trifluoromethyl)-1,3-thiazol-2-yl]pyrrolidin-1-yl]butanamide;(2R,3R)-4-[(2R)-2-(5,6-dihydro-4H-cyclopenta[d][1,3]thiazol-2-yl)pyrrolidin-1-yl]-2,3-dihydroxy-4-oxo-N-(2-thiophen-2-ylethyl)butanamide;(2R,3R)-2,3-dihydroxy-4-[2-(1H-imidazol-2-yl)pyrrolidin-1-yl]-N-[[4-[(2-methylphenyl)methyl]-1,3-thiazol-2-yl]methyl]-4-oxobutanamide;(2R,3R)-2,3-dihydroxy-4-[2-(1H-imidazol-2-yl)pyrrolidin-1-yl]-4-oxo-N-(2-thiophen-2-ylethyl)butanamide;(2R,3R)-2,3-dihydroxy-4-[(2R)-2-(4-methyl-1,3-thiazol-2-yl)pyrrolidin-1-yl]-4-oxo-N-(2-thiophen-2-ylethyl)butanamide;(2R,3R)-2,3-dihydroxy-4-oxo-N-(2-thiophen-2-ylethyl)-4-[(2R)-2-[4-(trifluoromethyl)-1,3-thiazol-2-yl]pyrrolidin-1-yl]butanamide;ethyl 2-[(2R)-1-[(2R,3R)-4-[[4-[(2-chlorophenyl)methyl]thiophen-2-yl]methylamino]-2,3-dihydroxy-4-oxobutanoyl]pyrrolidin-2-yl]-1,3-thiazole-4-carboxylate.

What is the SMILES notation for (2R,3R)-4-[(2R)-2-(2-amino-1,3-thiazol-4-yl)pyrrolidin-1-yl]-N-[[4-[(2-chlorophenyl)methyl]thiophen-2-yl]methyl]-2,3-dihydroxy-4-oxobutanamide;(2R,3R)-4-[(2R)-2-(4-tert-butyl-1,3-thiazol-2-yl)pyrrolidin-1-yl]-N-[[4-[(2-chlorophenyl)methyl]thiophen-2-yl]methyl]-2,3-dihydroxy-4-oxobutanamide;(2R,3R)-N-[[4-[(5-chloro-2-methylbenzimidazol-1-yl)methyl]-1,3-thiazol-2-yl]methyl]-4-[2-[3-(dimethylamino)phenyl]pyrrolidin-1-yl]-2,3-dihydroxy-4-oxobutanamide;(2R,3R)-N-[[4-[(2-chlorophenyl)methyl]thiophen-2-yl]methyl]-4-[(2R)-2-(5,6-dihydro-4H-cyclopenta[d][1,3]thiazol-2-yl)pyrrolidin-1-yl]-2,3-dihydroxy-4-oxobutanamide;(2R,3R)-N-[[4-[(2-chlorophenyl)methyl]thiophen-2-yl]methyl]-2,3-dihydroxy-4-[(2R)-2-(4-methyl-1,3-thiazol-2-yl)pyrrolidin-1-yl]-4-oxobutanamide;(2R,3R)-N-[[4-[(2-chlorophenyl)methyl]thiophen-2-yl]methyl]-2,3-dihydroxy-4-oxo-4-[(2R)-2-[4-(trifluoromethyl)-1,3-thiazol-2-yl]pyrrolidin-1-yl]butanamide;(2R,3R)-4-[(2R)-2-(5,6-dihydro-4H-cyclopenta[d][1,3]thiazol-2-yl)pyrrolidin-1-yl]-2,3-dihydroxy-4-oxo-N-(2-thiophen-2-ylethyl)butanamide;(2R,3R)-2,3-dihydroxy-4-[2-(1H-imidazol-2-yl)pyrrolidin-1-yl]-N-[[4-[(2-methylphenyl)methyl]-1,3-thiazol-2-yl]methyl]-4-oxobutanamide;(2R,3R)-2,3-dihydroxy-4-[2-(1H-imidazol-2-yl)pyrrolidin-1-yl]-4-oxo-N-(2-thiophen-2-ylethyl)butanamide;(2R,3R)-2,3-dihydroxy-4-[(2R)-2-(4-methyl-1,3-thiazol-2-yl)pyrrolidin-1-yl]-4-oxo-N-(2-thiophen-2-ylethyl)butanamide;(2R,3R)-2,3-dihydroxy-4-oxo-N-(2-thiophen-2-ylethyl)-4-[(2R)-2-[4-(trifluoromethyl)-1,3-thiazol-2-yl]pyrrolidin-1-yl]butanamide;ethyl 2-[(2R)-1-[(2R,3R)-4-[[4-[(2-chlorophenyl)methyl]thiophen-2-yl]methylamino]-2,3-dihydroxy-4-oxobutanoyl]pyrrolidin-2-yl]-1,3-thiazole-4-carboxylate?

The canonical SMILES for (2R,3R)-4-[(2R)-2-(2-amino-1,3-thiazol-4-yl)pyrrolidin-1-yl]-N-[[4-[(2-chlorophenyl)methyl]thiophen-2-yl]methyl]-2,3-dihydroxy-4-oxobutanamide;(2R,3R)-4-[(2R)-2-(4-tert-butyl-1,3-thiazol-2-yl)pyrrolidin-1-yl]-N-[[4-[(2-chlorophenyl)methyl]thiophen-2-yl]methyl]-2,3-dihydroxy-4-oxobutanamide;(2R,3R)-N-[[4-[(5-chloro-2-methylbenzimidazol-1-yl)methyl]-1,3-thiazol-2-yl]methyl]-4-[2-[3-(dimethylamino)phenyl]pyrrolidin-1-yl]-2,3-dihydroxy-4-oxobutanamide;(2R,3R)-N-[[4-[(2-chlorophenyl)methyl]thiophen-2-yl]methyl]-4-[(2R)-2-(5,6-dihydro-4H-cyclopenta[d][1,3]thiazol-2-yl)pyrrolidin-1-yl]-2,3-dihydroxy-4-oxobutanamide;(2R,3R)-N-[[4-[(2-chlorophenyl)methyl]thiophen-2-yl]methyl]-2,3-dihydroxy-4-[(2R)-2-(4-methyl-1,3-thiazol-2-yl)pyrrolidin-1-yl]-4-oxobutanamide;(2R,3R)-N-[[4-[(2-chlorophenyl)methyl]thiophen-2-yl]methyl]-2,3-dihydroxy-4-oxo-4-[(2R)-2-[4-(trifluoromethyl)-1,3-thiazol-2-yl]pyrrolidin-1-yl]butanamide;(2R,3R)-4-[(2R)-2-(5,6-dihydro-4H-cyclopenta[d][1,3]thiazol-2-yl)pyrrolidin-1-yl]-2,3-dihydroxy-4-oxo-N-(2-thiophen-2-ylethyl)butanamide;(2R,3R)-2,3-dihydroxy-4-[2-(1H-imidazol-2-yl)pyrrolidin-1-yl]-N-[[4-[(2-methylphenyl)methyl]-1,3-thiazol-2-yl]methyl]-4-oxobutanamide;(2R,3R)-2,3-dihydroxy-4-[2-(1H-imidazol-2-yl)pyrrolidin-1-yl]-4-oxo-N-(2-thiophen-2-ylethyl)butanamide;(2R,3R)-2,3-dihydroxy-4-[(2R)-2-(4-methyl-1,3-thiazol-2-yl)pyrrolidin-1-yl]-4-oxo-N-(2-thiophen-2-ylethyl)butanamide;(2R,3R)-2,3-dihydroxy-4-oxo-N-(2-thiophen-2-ylethyl)-4-[(2R)-2-[4-(trifluoromethyl)-1,3-thiazol-2-yl]pyrrolidin-1-yl]butanamide;ethyl 2-[(2R)-1-[(2R,3R)-4-[[4-[(2-chlorophenyl)methyl]thiophen-2-yl]methylamino]-2,3-dihydroxy-4-oxobutanoyl]pyrrolidin-2-yl]-1,3-thiazole-4-carboxylate is CC(C)(C)c1csc([C@H]2CCCN2C(=O)[C@H](O)[C@@H](O)C(=O)NCc2cc(Cc3ccccc3Cl)cs2)n1.CCOC(=O)c1csc([C@H]2CCCN2C(=O)[C@H](O)[C@@H](O)C(=O)NCc2cc(Cc3ccccc3Cl)cs2)n1.Cc1ccccc1Cc1csc(CNC(=O)[C@H](O)[C@@H](O)C(=O)N2CCCC2c2ncc[nH]2)n1.Cc1csc([C@H]2CCCN2C(=O)[C@H](O)[C@@H](O)C(=O)NCCc2cccs2)n1.Cc1csc([C@H]2CCCN2C(=O)[C@H](O)[C@@H](O)C(=O)NCc2cc(Cc3ccccc3Cl)cs2)n1.Cc1nc2cc(Cl)ccc2n1Cc1csc(CNC(=O)[C@H](O)[C@@H](O)C(=O)N2CCCC2c2cccc(N(C)C)c2)n1.Nc1nc([C@H]2CCCN2C(=O)[C@H](O)[C@@H](O)C(=O)NCc2cc(Cc3ccccc3Cl)cs2)cs1.O=C(NCCc1cccs1)[C@H](O)[C@@H](O)C(=O)N1CCCC1c1ncc[nH]1.O=C(NCCc1cccs1)[C@H](O)[C@@H](O)C(=O)N1CCC[C@@H]1c1nc(C(F)(F)F)cs1.O=C(NCCc1cccs1)[C@H](O)[C@@H](O)C(=O)N1CCC[C@@H]1c1nc2c(s1)CCC2.O=C(NCc1cc(Cc2ccccc2Cl)cs1)[C@H](O)[C@@H](O)C(=O)N1CCC[C@@H]1c1nc(C(F)(F)F)cs1.O=C(NCc1cc(Cc2ccccc2Cl)cs1)[C@H](O)[C@@H](O)C(=O)N1CCC[C@@H]1c1nc2c(s1)CCC2.

What is the InChIKey of (2R,3R)-4-[(2R)-2-(2-amino-1,3-thiazol-4-yl)pyrrolidin-1-yl]-N-[[4-[(2-chlorophenyl)methyl]thiophen-2-yl]methyl]-2,3-dihydroxy-4-oxobutanamide;(2R,3R)-4-[(2R)-2-(4-tert-butyl-1,3-thiazol-2-yl)pyrrolidin-1-yl]-N-[[4-[(2-chlorophenyl)methyl]thiophen-2-yl]methyl]-2,3-dihydroxy-4-oxobutanamide;(2R,3R)-N-[[4-[(5-chloro-2-methylbenzimidazol-1-yl)methyl]-1,3-thiazol-2-yl]methyl]-4-[2-[3-(dimethylamino)phenyl]pyrrolidin-1-yl]-2,3-dihydroxy-4-oxobutanamide;(2R,3R)-N-[[4-[(2-chlorophenyl)methyl]thiophen-2-yl]methyl]-4-[(2R)-2-(5,6-dihydro-4H-cyclopenta[d][1,3]thiazol-2-yl)pyrrolidin-1-yl]-2,3-dihydroxy-4-oxobutanamide;(2R,3R)-N-[[4-[(2-chlorophenyl)methyl]thiophen-2-yl]methyl]-2,3-dihydroxy-4-[(2R)-2-(4-methyl-1,3-thiazol-2-yl)pyrrolidin-1-yl]-4-oxobutanamide;(2R,3R)-N-[[4-[(2-chlorophenyl)methyl]thiophen-2-yl]methyl]-2,3-dihydroxy-4-oxo-4-[(2R)-2-[4-(trifluoromethyl)-1,3-thiazol-2-yl]pyrrolidin-1-yl]butanamide;(2R,3R)-4-[(2R)-2-(5,6-dihydro-4H-cyclopenta[d][1,3]thiazol-2-yl)pyrrolidin-1-yl]-2,3-dihydroxy-4-oxo-N-(2-thiophen-2-ylethyl)butanamide;(2R,3R)-2,3-dihydroxy-4-[2-(1H-imidazol-2-yl)pyrrolidin-1-yl]-N-[[4-[(2-methylphenyl)methyl]-1,3-thiazol-2-yl]methyl]-4-oxobutanamide;(2R,3R)-2,3-dihydroxy-4-[2-(1H-imidazol-2-yl)pyrrolidin-1-yl]-4-oxo-N-(2-thiophen-2-ylethyl)butanamide;(2R,3R)-2,3-dihydroxy-4-[(2R)-2-(4-methyl-1,3-thiazol-2-yl)pyrrolidin-1-yl]-4-oxo-N-(2-thiophen-2-ylethyl)butanamide;(2R,3R)-2,3-dihydroxy-4-oxo-N-(2-thiophen-2-ylethyl)-4-[(2R)-2-[4-(trifluoromethyl)-1,3-thiazol-2-yl]pyrrolidin-1-yl]butanamide;ethyl 2-[(2R)-1-[(2R,3R)-4-[[4-[(2-chlorophenyl)methyl]thiophen-2-yl]methylamino]-2,3-dihydroxy-4-oxobutanoyl]pyrrolidin-2-yl]-1,3-thiazole-4-carboxylate?

The InChIKey is KZPMAIHJPXBMSC-CBNSJUFKSA-N. The full InChI is InChI=1S/C29H33ClN6O4S.C27H32ClN3O4S2.C26H28ClN3O6S2.C26H28ClN3O4S2.C24H23ClF3N3O4S2.C24H26ClN3O4S2.C23H25ClN4O4S2.C23H27N5O4S.C20H25N3O4S2.C18H20F3N3O4S2.C18H23N3O4S2.C17H22N4O4S/c1-17-32-22-13-19(30)9-10-24(22)36(17)15-20-16-41-25(33-20)14-31-28(39)26(37)27(38)29(40)35-11-5-8-23(35)18-6-4-7-21(12-18)34(2)3;1-27(2,3)21-15-37-25(30-21)20-9-6-10-31(20)26(35)23(33)22(32)24(34)29-13-18-12-16(14-36-18)11-17-7-4-5-8-19(17)28;1-2-36-26(35)19-14-38-24(29-19)20-8-5-9-30(20)25(34)22(32)21(31)23(33)28-12-17-11-15(13-37-17)10-16-6-3-4-7-18(16)27;27-18-6-2-1-5-16(18)11-15-12-17(35-14-15)13-28-24(33)22(31)23(32)26(34)30-10-4-8-20(30)25-29-19-7-3-9-21(19)36-25;25-16-5-2-1-4-14(16)8-13-9-15(36-11-13)10-29-21(34)19(32)20(33)23(35)31-7-3-6-17(31)22-30-18(12-37-22)24(26,27)28;1-14-12-34-23(27-14)19-7-4-8-28(19)24(32)21(30)20(29)22(31)26-11-17-10-15(13-33-17)9-16-5-2-3-6-18(16)25;24-16-5-2-1-4-14(16)8-13-9-15(33-11-13)10-26-21(31)19(29)20(30)22(32)28-7-3-6-18(28)17-12-34-23(25)27-17;1-14-5-2-3-6-15(14)11-16-13-33-18(27-16)12-26-22(31)19(29)20(30)23(32)28-10-4-7-17(28)21-24-8-9-25-21;24-16(18(26)21-9-8-12-4-3-11-28-12)17(25)20(27)23-10-2-6-14(23)19-22-13-5-1-7-15(13)29-19;19-18(20,21)12-9-30-16(23-12)11-4-1-7-24(11)17(28)14(26)13(25)15(27)22-6-5-10-3-2-8-29-10;1-11-10-27-17(20-11)13-5-2-8-21(13)18(25)15(23)14(22)16(24)19-7-6-12-4-3-9-26-12;22-13(16(24)20-6-5-11-3-2-10-26-11)14(23)17(25)21-9-1-4-12(21)15-18-7-8-19-15/h4,6-7,9-10,12-13,16,23,26-27,37-38H,5,8,11,14-15H2,1-3H3,(H,31,39);4-5,7-8,12,14-15,20,22-23,32-33H,6,9-11,13H2,1-3H3,(H,29,34);3-4,6-7,11,13-14,20-22,31-32H,2,5,8-10,12H2,1H3,(H,28,33);1-2,5-6,12,14,20,22-23,31-32H,3-4,7-11,13H2,(H,28,33);1-2,4-5,9,11-12,17,19-20,32-33H,3,6-8,10H2,(H,29,34);2-3,5-6,10,12-13,19-21,29-30H,4,7-9,11H2,1H3,(H,26,31);1-2,4-5,9,11-12,18-20,29-30H,3,6-8,10H2,(H2,25,27)(H,26,31);2-3,5-6,8-9,13,17,19-20,29-30H,4,7,10-12H2,1H3,(H,24,25)(H,26,31);3-4,11,14,16-17,24-25H,1-2,5-10H2,(H,21,26);2-3,8-9,11,13-14,25-26H,1,4-7H2,(H,22,27);3-4,9-10,13-15,22-23H,2,5-8H2,1H3,(H,19,24);2-3,7-8,10,12-14,22-23H,1,4-6,9H2,(H,18,19)(H,20,24)/t23?,26-,27-;20-,22-,23-;20-,21-,22-;20-,22-,23-;17-,19-,20-;19-,20-,21-;18-,19-,20-;17?,19-,20-;14-,16-,17-;11-,13-,14-;13-,14-,15-;12?,13-,14-/m111111111111/s1.

What are the key properties of (2R,3R)-4-[(2R)-2-(2-amino-1,3-thiazol-4-yl)pyrrolidin-1-yl]-N-[[4-[(2-chlorophenyl)methyl]thiophen-2-yl]methyl]-2,3-dihydroxy-4-oxobutanamide;(2R,3R)-4-[(2R)-2-(4-tert-butyl-1,3-thiazol-2-yl)pyrrolidin-1-yl]-N-[[4-[(2-chlorophenyl)methyl]thiophen-2-yl]methyl]-2,3-dihydroxy-4-oxobutanamide;(2R,3R)-N-[[4-[(5-chloro-2-methylbenzimidazol-1-yl)methyl]-1,3-thiazol-2-yl]methyl]-4-[2-[3-(dimethylamino)phenyl]pyrrolidin-1-yl]-2,3-dihydroxy-4-oxobutanamide;(2R,3R)-N-[[4-[(2-chlorophenyl)methyl]thiophen-2-yl]methyl]-4-[(2R)-2-(5,6-dihydro-4H-cyclopenta[d][1,3]thiazol-2-yl)pyrrolidin-1-yl]-2,3-dihydroxy-4-oxobutanamide;(2R,3R)-N-[[4-[(2-chlorophenyl)methyl]thiophen-2-yl]methyl]-2,3-dihydroxy-4-[(2R)-2-(4-methyl-1,3-thiazol-2-yl)pyrrolidin-1-yl]-4-oxobutanamide;(2R,3R)-N-[[4-[(2-chlorophenyl)methyl]thiophen-2-yl]methyl]-2,3-dihydroxy-4-oxo-4-[(2R)-2-[4-(trifluoromethyl)-1,3-thiazol-2-yl]pyrrolidin-1-yl]butanamide;(2R,3R)-4-[(2R)-2-(5,6-dihydro-4H-cyclopenta[d][1,3]thiazol-2-yl)pyrrolidin-1-yl]-2,3-dihydroxy-4-oxo-N-(2-thiophen-2-ylethyl)butanamide;(2R,3R)-2,3-dihydroxy-4-[2-(1H-imidazol-2-yl)pyrrolidin-1-yl]-N-[[4-[(2-methylphenyl)methyl]-1,3-thiazol-2-yl]methyl]-4-oxobutanamide;(2R,3R)-2,3-dihydroxy-4-[2-(1H-imidazol-2-yl)pyrrolidin-1-yl]-4-oxo-N-(2-thiophen-2-ylethyl)butanamide;(2R,3R)-2,3-dihydroxy-4-[(2R)-2-(4-methyl-1,3-thiazol-2-yl)pyrrolidin-1-yl]-4-oxo-N-(2-thiophen-2-ylethyl)butanamide;(2R,3R)-2,3-dihydroxy-4-oxo-N-(2-thiophen-2-ylethyl)-4-[(2R)-2-[4-(trifluoromethyl)-1,3-thiazol-2-yl]pyrrolidin-1-yl]butanamide;ethyl 2-[(2R)-1-[(2R,3R)-4-[[4-[(2-chlorophenyl)methyl]thiophen-2-yl]methylamino]-2,3-dihydroxy-4-oxobutanoyl]pyrrolidin-2-yl]-1,3-thiazole-4-carboxylate?

(2R,3R)-4-[(2R)-2-(2-amino-1,3-thiazol-4-yl)pyrrolidin-1-yl]-N-[[4-[(2-chlorophenyl)methyl]thiophen-2-yl]methyl]-2,3-dihydroxy-4-oxobutanamide;(2R,3R)-4-[(2R)-2-(4-tert-butyl-1,3-thiazol-2-yl)pyrrolidin-1-yl]-N-[[4-[(2-chlorophenyl)methyl]thiophen-2-yl]methyl]-2,3-dihydroxy-4-oxobutanamide;(2R,3R)-N-[[4-[(5-chloro-2-methylbenzimidazol-1-yl)methyl]-1,3-thiazol-2-yl]methyl]-4-[2-[3-(dimethylamino)phenyl]pyrrolidin-1-yl]-2,3-dihydroxy-4-oxobutanamide;(2R,3R)-N-[[4-[(2-chlorophenyl)methyl]thiophen-2-yl]methyl]-4-[(2R)-2-(5,6-dihydro-4H-cyclopenta[d][1,3]thiazol-2-yl)pyrrolidin-1-yl]-2,3-dihydroxy-4-oxobutanamide;(2R,3R)-N-[[4-[(2-chlorophenyl)methyl]thiophen-2-yl]methyl]-2,3-dihydroxy-4-[(2R)-2-(4-methyl-1,3-thiazol-2-yl)pyrrolidin-1-yl]-4-oxobutanamide;(2R,3R)-N-[[4-[(2-chlorophenyl)methyl]thiophen-2-yl]methyl]-2,3-dihydroxy-4-oxo-4-[(2R)-2-[4-(trifluoromethyl)-1,3-thiazol-2-yl]pyrrolidin-1-yl]butanamide;(2R,3R)-4-[(2R)-2-(5,6-dihydro-4H-cyclopenta[d][1,3]thiazol-2-yl)pyrrolidin-1-yl]-2,3-dihydroxy-4-oxo-N-(2-thiophen-2-ylethyl)butanamide;(2R,3R)-2,3-dihydroxy-4-[2-(1H-imidazol-2-yl)pyrrolidin-1-yl]-N-[[4-[(2-methylphenyl)methyl]-1,3-thiazol-2-yl]methyl]-4-oxobutanamide;(2R,3R)-2,3-dihydroxy-4-[2-(1H-imidazol-2-yl)pyrrolidin-1-yl]-4-oxo-N-(2-thiophen-2-ylethyl)butanamide;(2R,3R)-2,3-dihydroxy-4-[(2R)-2-(4-methyl-1,3-thiazol-2-yl)pyrrolidin-1-yl]-4-oxo-N-(2-thiophen-2-ylethyl)butanamide;(2R,3R)-2,3-dihydroxy-4-oxo-N-(2-thiophen-2-ylethyl)-4-[(2R)-2-[4-(trifluoromethyl)-1,3-thiazol-2-yl]pyrrolidin-1-yl]butanamide;ethyl 2-[(2R)-1-[(2R,3R)-4-[[4-[(2-chlorophenyl)methyl]thiophen-2-yl]methylamino]-2,3-dihydroxy-4-oxobutanoyl]pyrrolidin-2-yl]-1,3-thiazole-4-carboxylate has a molecular weight of 6055.34 g/mol, XLogP of 31.39, 95 rotatable bonds, 39 hydrogen bond donors, and 88 hydrogen bond acceptors.

Where does this data come from?

All data for (2R,3R)-4-[(2R)-2-(2-amino-1,3-thiazol-4-yl)pyrrolidin-1-yl]-N-[[4-[(2-chlorophenyl)methyl]thiophen-2-yl]methyl]-2,3-dihydroxy-4-oxobutanamide;(2R,3R)-4-[(2R)-2-(4-tert-butyl-1,3-thiazol-2-yl)pyrrolidin-1-yl]-N-[[4-[(2-chlorophenyl)methyl]thiophen-2-yl]methyl]-2,3-dihydroxy-4-oxobutanamide;(2R,3R)-N-[[4-[(5-chloro-2-methylbenzimidazol-1-yl)methyl]-1,3-thiazol-2-yl]methyl]-4-[2-[3-(dimethylamino)phenyl]pyrrolidin-1-yl]-2,3-dihydroxy-4-oxobutanamide;(2R,3R)-N-[[4-[(2-chlorophenyl)methyl]thiophen-2-yl]methyl]-4-[(2R)-2-(5,6-dihydro-4H-cyclopenta[d][1,3]thiazol-2-yl)pyrrolidin-1-yl]-2,3-dihydroxy-4-oxobutanamide;(2R,3R)-N-[[4-[(2-chlorophenyl)methyl]thiophen-2-yl]methyl]-2,3-dihydroxy-4-[(2R)-2-(4-methyl-1,3-thiazol-2-yl)pyrrolidin-1-yl]-4-oxobutanamide;(2R,3R)-N-[[4-[(2-chlorophenyl)methyl]thiophen-2-yl]methyl]-2,3-dihydroxy-4-oxo-4-[(2R)-2-[4-(trifluoromethyl)-1,3-thiazol-2-yl]pyrrolidin-1-yl]butanamide;(2R,3R)-4-[(2R)-2-(5,6-dihydro-4H-cyclopenta[d][1,3]thiazol-2-yl)pyrrolidin-1-yl]-2,3-dihydroxy-4-oxo-N-(2-thiophen-2-ylethyl)butanamide;(2R,3R)-2,3-dihydroxy-4-[2-(1H-imidazol-2-yl)pyrrolidin-1-yl]-N-[[4-[(2-methylphenyl)methyl]-1,3-thiazol-2-yl]methyl]-4-oxobutanamide;(2R,3R)-2,3-dihydroxy-4-[2-(1H-imidazol-2-yl)pyrrolidin-1-yl]-4-oxo-N-(2-thiophen-2-ylethyl)butanamide;(2R,3R)-2,3-dihydroxy-4-[(2R)-2-(4-methyl-1,3-thiazol-2-yl)pyrrolidin-1-yl]-4-oxo-N-(2-thiophen-2-ylethyl)butanamide;(2R,3R)-2,3-dihydroxy-4-oxo-N-(2-thiophen-2-ylethyl)-4-[(2R)-2-[4-(trifluoromethyl)-1,3-thiazol-2-yl]pyrrolidin-1-yl]butanamide;ethyl 2-[(2R)-1-[(2R,3R)-4-[[4-[(2-chlorophenyl)methyl]thiophen-2-yl]methylamino]-2,3-dihydroxy-4-oxobutanoyl]pyrrolidin-2-yl]-1,3-thiazole-4-carboxylate is sourced from PubChem (CID 159286767), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).