6-cyclopropyl-2-methyl-N-[3-[5-(trifluoromethyl)-2-pyridinyl]oxolan-3-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;2,6-dimethyl-N-[3-[5-(trifluoromethyl)-2-pyridinyl]oxolan-3-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;2,6-dimethyl-N-[3-[6-(trifluoromethyl)-3-pyridinyl]oxolan-3-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[4-[2-fluoro-4-(trifluoromethyl)phenyl]-3-hydroxyoxan-4-yl]-6-methylpyrazolo[1,5-a]pyrimidine-3-carboxamide

C79H74F13N19O9 — CID 159294282

IUPAC6-cyclopropyl-2-methyl-N-[3-[5-(trifluoromethyl)-2-pyridinyl]oxolan-3-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;2,6-dimethyl-N-[3-[5-(trifluoromethyl)-2-pyridinyl]oxolan-3-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;2,6-dimethyl-N-[3-[6-(trifluoromethyl)-3-pyridinyl]oxolan-3-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[4-[2-fluoro-4-(trifluoromethyl)phenyl]-3-hydroxyoxan-4-yl]-6-methylpyrazolo[1,5-a]pyrimidine-3-carboxamide
SMILESCc1cnc2c(C(=O)NC3(c4ccc(C(F)(F)F)cc4F)CCOCC3O)cnn2c1.Cc1cnc2c(C(=O)NC3(c4ccc(C(F)(F)F)cn4)CCOC3)c(C)nn2c1.Cc1cnc2c(C(=O)NC3(c4ccc(C(F)(F)F)nc4)CCOC3)c(C)nn2c1.Cc1nn2cc(C3CC3)cnc2c1C(=O)NC1(c2ccc(C(F)(F)F)cn2)CCOC1
InChIInChI=1S/C21H20F3N5O2.C20H18F4N4O3.2C19H18F3N5O2/c1-12-17(18-26-8-14(13-2-3-13)10-29(18)28-12)19(30)27-20(6-7-31-11-20)16-5-4-15(9-25-16)21(22,23)24;1-11-7-25-17-13(8-26-28(17)9-11)18(30)27-19(4-5-31-10-16(19)29)14-3-2-12(6-15(14)21)20(22,23)24;1-11-7-24-16-15(12(2)26-27(16)9-11)17(28)25-18(5-6-29-10-18)14-4-3-13(8-23-14)19(20,21)22;1-11-7-24-16-15(12(2)26-27(16)9-11)17(28)25-18(5-6-29-10-18)13-3-4-14(23-8-13)19(20,21)22/h4-5,8-10,13H,2-3,6-7,11H2,1H3,(H,27,30);2-3,6-9,16,29H,4-5,10H2,1H3,(H,27,30);2*3-4,7-9H,5-6,10H2,1-2H3,(H,25,28)
InChIKeyLANBNKWCHRNRBG-UHFFFAOYSA-N
MW1680.56 g/mol
LogP11.59
Rot. Bonds13

About 6-cyclopropyl-2-methyl-N-[3-[5-(trifluoromethyl)-2-pyridinyl]oxolan-3-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;2,6-dimethyl-N-[3-[5-(trifluoromethyl)-2-pyridinyl]oxolan-3-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;2,6-dimethyl-N-[3-[6-(trifluoromethyl)-3-pyridinyl]oxolan-3-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[4-[2-fluoro-4-(trifluoromethyl)phenyl]-3-hydroxyoxan-4-yl]-6-methylpyrazolo[1,5-a]pyrimidine-3-carboxamide

6-cyclopropyl-2-methyl-N-[3-[5-(trifluoromethyl)-2-pyridinyl]oxolan-3-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;2,6-dimethyl-N-[3-[5-(trifluoromethyl)-2-pyridinyl]oxolan-3-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;2,6-dimethyl-N-[3-[6-(trifluoromethyl)-3-pyridinyl]oxolan-3-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[4-[2-fluoro-4-(trifluoromethyl)phenyl]-3-hydroxyoxan-4-yl]-6-methylpyrazolo[1,5-a]pyrimidine-3-carboxamide (PubChem CID 159294282) has the molecular formula C79H74F13N19O9 and a molecular weight of 1680.56 g/mol. Its IUPAC name is 6-cyclopropyl-2-methyl-N-[3-[5-(trifluoromethyl)-2-pyridinyl]oxolan-3-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;2,6-dimethyl-N-[3-[5-(trifluoromethyl)-2-pyridinyl]oxolan-3-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;2,6-dimethyl-N-[3-[6-(trifluoromethyl)-3-pyridinyl]oxolan-3-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[4-[2-fluoro-4-(trifluoromethyl)phenyl]-3-hydroxyoxan-4-yl]-6-methylpyrazolo[1,5-a]pyrimidine-3-carboxamide.

Molecular Properties

Compound Name6-cyclopropyl-2-methyl-N-[3-[5-(trifluoromethyl)-2-pyridinyl]oxolan-3-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;2,6-dimethyl-N-[3-[5-(trifluoromethyl)-2-pyridinyl]oxolan-3-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;2,6-dimethyl-N-[3-[6-(trifluoromethyl)-3-pyridinyl]oxolan-3-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[4-[2-fluoro-4-(trifluoromethyl)phenyl]-3-hydroxyoxan-4-yl]-6-methylpyrazolo[1,5-a]pyrimidine-3-carboxamide
PubChem CID159294282
Molecular FormulaC79H74F13N19O9
Molecular Weight1680.56 g/mol
Exact Mass1679.57
IUPAC Name6-cyclopropyl-2-methyl-N-[3-[5-(trifluoromethyl)-2-pyridinyl]oxolan-3-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;2,6-dimethyl-N-[3-[5-(trifluoromethyl)-2-pyridinyl]oxolan-3-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;2,6-dimethyl-N-[3-[6-(trifluoromethyl)-3-pyridinyl]oxolan-3-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[4-[2-fluoro-4-(trifluoromethyl)phenyl]-3-hydroxyoxan-4-yl]-6-methylpyrazolo[1,5-a]pyrimidine-3-carboxamide
SMILESCc1cnc2c(C(=O)NC3(c4ccc(C(F)(F)F)cc4F)CCOCC3O)cnn2c1.Cc1cnc2c(C(=O)NC3(c4ccc(C(F)(F)F)cn4)CCOC3)c(C)nn2c1.Cc1cnc2c(C(=O)NC3(c4ccc(C(F)(F)F)nc4)CCOC3)c(C)nn2c1.Cc1nn2cc(C3CC3)cnc2c1C(=O)NC1(c2ccc(C(F)(F)F)cn2)CCOC1
InChIInChI=1S/C21H20F3N5O2.C20H18F4N4O3.2C19H18F3N5O2/c1-12-17(18-26-8-14(13-2-3-13)10-29(18)28-12)19(30)27-20(6-7-31-11-20)16-5-4-15(9-25-16)21(22,23)24;1-11-7-25-17-13(8-26-28(17)9-11)18(30)27-19(4-5-31-10-16(19)29)14-3-2-12(6-15(14)21)20(22,23)24;1-11-7-24-16-15(12(2)26-27(16)9-11)17(28)25-18(5-6-29-10-18)14-4-3-13(8-23-14)19(20,21)22;1-11-7-24-16-15(12(2)26-27(16)9-11)17(28)25-18(5-6-29-10-18)13-3-4-14(23-8-13)19(20,21)22/h4-5,8-10,13H,2-3,6-7,11H2,1H3,(H,27,30);2-3,6-9,16,29H,4-5,10H2,1H3,(H,27,30);2*3-4,7-9H,5-6,10H2,1-2H3,(H,25,28)
InChIKeyLANBNKWCHRNRBG-UHFFFAOYSA-N
XLogP11.59
TPSA332.98 Ų
H-Bond Donors5
H-Bond Acceptors24
Rotatable Bonds13
Heavy Atoms120
Complexity—

Lipinski Rule of Five

3 violations

RuleValue
MW ≤ 5001680.56
LogP ≤ 511.59
H-Bond Donors ≤ 55
H-Bond Acceptors ≤ 1024

Analyze 6-cyclopropyl-2-methyl-N-[3-[5-(trifluoromethyl)-2-pyridinyl]oxolan-3-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;2,6-dimethyl-N-[3-[5-(trifluoromethyl)-2-pyridinyl]oxolan-3-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;2,6-dimethyl-N-[3-[6-(trifluoromethyl)-3-pyridinyl]oxolan-3-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[4-[2-fluoro-4-(trifluoromethyl)phenyl]-3-hydroxyoxan-4-yl]-6-methylpyrazolo[1,5-a]pyrimidine-3-carboxamide with MolForge

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Related Compounds

US10023575, Example 89a
CID 126763818
US10023575, Example 90a
CID 126763820
US10023575, Example 65
CID 126763822
US10023575, Example 63
CID 126763829
US10023575, Example 88a
CID 126763869
US10875867, Example 90b
CID 135224311
US10875867, Example 88a
CID 156023205
US10875867, Example 89a
CID 156023206
US10875867, Example 90a
CID 156023207
US11691977, Example 88a
CID 168474828
US11691977, Example 89a
CID 168474830
US11691977, Example 90a
CID 168474831

Frequently Asked Questions

What is the IUPAC name of 6-cyclopropyl-2-methyl-N-[3-[5-(trifluoromethyl)-2-pyridinyl]oxolan-3-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;2,6-dimethyl-N-[3-[5-(trifluoromethyl)-2-pyridinyl]oxolan-3-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;2,6-dimethyl-N-[3-[6-(trifluoromethyl)-3-pyridinyl]oxolan-3-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[4-[2-fluoro-4-(trifluoromethyl)phenyl]-3-hydroxyoxan-4-yl]-6-methylpyrazolo[1,5-a]pyrimidine-3-carboxamide?
The IUPAC name of 6-cyclopropyl-2-methyl-N-[3-[5-(trifluoromethyl)-2-pyridinyl]oxolan-3-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;2,6-dimethyl-N-[3-[5-(trifluoromethyl)-2-pyridinyl]oxolan-3-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;2,6-dimethyl-N-[3-[6-(trifluoromethyl)-3-pyridinyl]oxolan-3-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[4-[2-fluoro-4-(trifluoromethyl)phenyl]-3-hydroxyoxan-4-yl]-6-methylpyrazolo[1,5-a]pyrimidine-3-carboxamide (CID 159294282) is 6-cyclopropyl-2-methyl-N-[3-[5-(trifluoromethyl)-2-pyridinyl]oxolan-3-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;2,6-dimethyl-N-[3-[5-(trifluoromethyl)-2-pyridinyl]oxolan-3-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;2,6-dimethyl-N-[3-[6-(trifluoromethyl)-3-pyridinyl]oxolan-3-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[4-[2-fluoro-4-(trifluoromethyl)phenyl]-3-hydroxyoxan-4-yl]-6-methylpyrazolo[1,5-a]pyrimidine-3-carboxamide.
What is the SMILES notation for 6-cyclopropyl-2-methyl-N-[3-[5-(trifluoromethyl)-2-pyridinyl]oxolan-3-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;2,6-dimethyl-N-[3-[5-(trifluoromethyl)-2-pyridinyl]oxolan-3-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;2,6-dimethyl-N-[3-[6-(trifluoromethyl)-3-pyridinyl]oxolan-3-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[4-[2-fluoro-4-(trifluoromethyl)phenyl]-3-hydroxyoxan-4-yl]-6-methylpyrazolo[1,5-a]pyrimidine-3-carboxamide?
The canonical SMILES for 6-cyclopropyl-2-methyl-N-[3-[5-(trifluoromethyl)-2-pyridinyl]oxolan-3-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;2,6-dimethyl-N-[3-[5-(trifluoromethyl)-2-pyridinyl]oxolan-3-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;2,6-dimethyl-N-[3-[6-(trifluoromethyl)-3-pyridinyl]oxolan-3-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[4-[2-fluoro-4-(trifluoromethyl)phenyl]-3-hydroxyoxan-4-yl]-6-methylpyrazolo[1,5-a]pyrimidine-3-carboxamide is Cc1cnc2c(C(=O)NC3(c4ccc(C(F)(F)F)cc4F)CCOCC3O)cnn2c1.Cc1cnc2c(C(=O)NC3(c4ccc(C(F)(F)F)cn4)CCOC3)c(C)nn2c1.Cc1cnc2c(C(=O)NC3(c4ccc(C(F)(F)F)nc4)CCOC3)c(C)nn2c1.Cc1nn2cc(C3CC3)cnc2c1C(=O)NC1(c2ccc(C(F)(F)F)cn2)CCOC1.
What is the InChIKey of 6-cyclopropyl-2-methyl-N-[3-[5-(trifluoromethyl)-2-pyridinyl]oxolan-3-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;2,6-dimethyl-N-[3-[5-(trifluoromethyl)-2-pyridinyl]oxolan-3-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;2,6-dimethyl-N-[3-[6-(trifluoromethyl)-3-pyridinyl]oxolan-3-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[4-[2-fluoro-4-(trifluoromethyl)phenyl]-3-hydroxyoxan-4-yl]-6-methylpyrazolo[1,5-a]pyrimidine-3-carboxamide?
The InChIKey is LANBNKWCHRNRBG-UHFFFAOYSA-N. The full InChI is InChI=1S/C21H20F3N5O2.C20H18F4N4O3.2C19H18F3N5O2/c1-12-17(18-26-8-14(13-2-3-13)10-29(18)28-12)19(30)27-20(6-7-31-11-20)16-5-4-15(9-25-16)21(22,23)24;1-11-7-25-17-13(8-26-28(17)9-11)18(30)27-19(4-5-31-10-16(19)29)14-3-2-12(6-15(14)21)20(22,23)24;1-11-7-24-16-15(12(2)26-27(16)9-11)17(28)25-18(5-6-29-10-18)14-4-3-13(8-23-14)19(20,21)22;1-11-7-24-16-15(12(2)26-27(16)9-11)17(28)25-18(5-6-29-10-18)13-3-4-14(23-8-13)19(20,21)22/h4-5,8-10,13H,2-3,6-7,11H2,1H3,(H,27,30);2-3,6-9,16,29H,4-5,10H2,1H3,(H,27,30);2*3-4,7-9H,5-6,10H2,1-2H3,(H,25,28).
What are the key properties of 6-cyclopropyl-2-methyl-N-[3-[5-(trifluoromethyl)-2-pyridinyl]oxolan-3-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;2,6-dimethyl-N-[3-[5-(trifluoromethyl)-2-pyridinyl]oxolan-3-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;2,6-dimethyl-N-[3-[6-(trifluoromethyl)-3-pyridinyl]oxolan-3-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[4-[2-fluoro-4-(trifluoromethyl)phenyl]-3-hydroxyoxan-4-yl]-6-methylpyrazolo[1,5-a]pyrimidine-3-carboxamide?
6-cyclopropyl-2-methyl-N-[3-[5-(trifluoromethyl)-2-pyridinyl]oxolan-3-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;2,6-dimethyl-N-[3-[5-(trifluoromethyl)-2-pyridinyl]oxolan-3-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;2,6-dimethyl-N-[3-[6-(trifluoromethyl)-3-pyridinyl]oxolan-3-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[4-[2-fluoro-4-(trifluoromethyl)phenyl]-3-hydroxyoxan-4-yl]-6-methylpyrazolo[1,5-a]pyrimidine-3-carboxamide has a molecular weight of 1680.56 g/mol, XLogP of 11.59, 13 rotatable bonds, 5 hydrogen bond donors, and 24 hydrogen bond acceptors.
Where does this data come from?
All data for 6-cyclopropyl-2-methyl-N-[3-[5-(trifluoromethyl)-2-pyridinyl]oxolan-3-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;2,6-dimethyl-N-[3-[5-(trifluoromethyl)-2-pyridinyl]oxolan-3-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;2,6-dimethyl-N-[3-[6-(trifluoromethyl)-3-pyridinyl]oxolan-3-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[4-[2-fluoro-4-(trifluoromethyl)phenyl]-3-hydroxyoxan-4-yl]-6-methylpyrazolo[1,5-a]pyrimidine-3-carboxamide is sourced from PubChem (CID 159294282), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).