5-chloro-N-[2-(2-cyclopropyl-4-piperidin-1-ylphenyl)ethyl]-3-ethyl-1H-indole-2-carboxamide;5-chloro-3-ethyl-N-[(2R)-2-hydroxy-2-(4-piperidin-1-ylphenyl)ethyl]-1H-indole-2-carboxamide;5-chloro-3-ethyl-N-[(2S)-2-hydroxy-2-(4-piperidin-1-ylphenyl)ethyl]-1H-indole-2-carboxamide;5-chloro-3-ethyl-N-[2-(4-piperidin-1-ylphenyl)ethyl]-1H-indole-2-carboxamide;5-chloro-3-ethyl-N-[2-(5-piperidin-1-yl-2-pyridinyl)ethyl]-1H-indole-2-carboxamide;3-ethyl-6-fluoro-N-[2-(4-piperidin-1-ylphenyl)ethyl]-1H-indole-2-carboxamide

C146H171Cl5FN19O8 — CID 159320437

About 5-chloro-N-[2-(2-cyclopropyl-4-piperidin-1-ylphenyl)ethyl]-3-ethyl-1H-indole-2-carboxamide;5-chloro-3-ethyl-N-[(2R)-2-hydroxy-2-(4-piperidin-1-ylphenyl)ethyl]-1H-indole-2-carboxamide;5-chloro-3-ethyl-N-[(2S)-2-hydroxy-2-(4-piperidin-1-ylphenyl)ethyl]-1H-indole-2-carboxamide;5-chloro-3-ethyl-N-[2-(4-piperidin-1-ylphenyl)ethyl]-1H-indole-2-carboxamide;5-chloro-3-ethyl-N-[2-(5-piperidin-1-yl-2-pyridinyl)ethyl]-1H-indole-2-carboxamide;3-ethyl-6-fluoro-N-[2-(4-piperidin-1-ylphenyl)ethyl]-1H-indole-2-carboxamide

5-chloro-N-[2-(2-cyclopropyl-4-piperidin-1-ylphenyl)ethyl]-3-ethyl-1H-indole-2-carboxamide;5-chloro-3-ethyl-N-[(2R)-2-hydroxy-2-(4-piperidin-1-ylphenyl)ethyl]-1H-indole-2-carboxamide;5-chloro-3-ethyl-N-[(2S)-2-hydroxy-2-(4-piperidin-1-ylphenyl)ethyl]-1H-indole-2-carboxamide;5-chloro-3-ethyl-N-[2-(4-piperidin-1-ylphenyl)ethyl]-1H-indole-2-carboxamide;5-chloro-3-ethyl-N-[2-(5-piperidin-1-yl-2-pyridinyl)ethyl]-1H-indole-2-carboxamide;3-ethyl-6-fluoro-N-[2-(4-piperidin-1-ylphenyl)ethyl]-1H-indole-2-carboxamide (PubChem CID 159320437) has the molecular formula C146H171Cl5FN19O8 and a molecular weight of 2516.36 g/mol. Its IUPAC name is 5-chloro-N-[2-(2-cyclopropyl-4-piperidin-1-ylphenyl)ethyl]-3-ethyl-1H-indole-2-carboxamide;5-chloro-3-ethyl-N-[(2R)-2-hydroxy-2-(4-piperidin-1-ylphenyl)ethyl]-1H-indole-2-carboxamide;5-chloro-3-ethyl-N-[(2S)-2-hydroxy-2-(4-piperidin-1-ylphenyl)ethyl]-1H-indole-2-carboxamide;5-chloro-3-ethyl-N-[2-(4-piperidin-1-ylphenyl)ethyl]-1H-indole-2-carboxamide;5-chloro-3-ethyl-N-[2-(5-piperidin-1-yl-2-pyridinyl)ethyl]-1H-indole-2-carboxamide;3-ethyl-6-fluoro-N-[2-(4-piperidin-1-ylphenyl)ethyl]-1H-indole-2-carboxamide.

Molecular Properties

• Compound Name: 5-chloro-N-[2-(2-cyclopropyl-4-piperidin-1-ylphenyl)ethyl]-3-ethyl-1H-indole-2-carboxamide;5-chloro-3-ethyl-N-[(2R)-2-hydroxy-2-(4-piperidin-1-ylphenyl)ethyl]-1H-indole-2-carboxamide;5-chloro-3-ethyl-N-[(2S)-2-hydroxy-2-(4-piperidin-1-ylphenyl)ethyl]-1H-indole-2-carboxamide;5-chloro-3-ethyl-N-[2-(4-piperidin-1-ylphenyl)ethyl]-1H-indole-2-carboxamide;5-chloro-3-ethyl-N-[2-(5-piperidin-1-yl-2-pyridinyl)ethyl]-1H-indole-2-carboxamide;3-ethyl-6-fluoro-N-[2-(4-piperidin-1-ylphenyl)ethyl]-1H-indole-2-carboxamide
• PubChem CID: 159320437
• Molecular Formula: C146H171Cl5FN19O8
• Molecular Weight: 2516.36 g/mol
• Exact Mass: 2512.20
• IUPAC Name: 5-chloro-N-[2-(2-cyclopropyl-4-piperidin-1-ylphenyl)ethyl]-3-ethyl-1H-indole-2-carboxamide;5-chloro-3-ethyl-N-[(2R)-2-hydroxy-2-(4-piperidin-1-ylphenyl)ethyl]-1H-indole-2-carboxamide;5-chloro-3-ethyl-N-[(2S)-2-hydroxy-2-(4-piperidin-1-ylphenyl)ethyl]-1H-indole-2-carboxamide;5-chloro-3-ethyl-N-[2-(4-piperidin-1-ylphenyl)ethyl]-1H-indole-2-carboxamide;5-chloro-3-ethyl-N-[2-(5-piperidin-1-yl-2-pyridinyl)ethyl]-1H-indole-2-carboxamide;3-ethyl-6-fluoro-N-[2-(4-piperidin-1-ylphenyl)ethyl]-1H-indole-2-carboxamide
• SMILES: CCc1c(C(=O)NCCc2ccc(N3CCCCC3)cc2)[nH]c2cc(F)ccc12.CCc1c(C(=O)NCCc2ccc(N3CCCCC3)cc2)[nH]c2ccc(Cl)cc12.CCc1c(C(=O)NCCc2ccc(N3CCCCC3)cc2C2CC2)[nH]c2ccc(Cl)cc12.CCc1c(C(=O)NCCc2ccc(N3CCCCC3)cn2)[nH]c2ccc(Cl)cc12.CCc1c(C(=O)NC[C@@H](O)c2ccc(N3CCCCC3)cc2)[nH]c2ccc(Cl)cc12.CCc1c(C(=O)NC[C@H](O)c2ccc(N3CCCCC3)cc2)[nH]c2ccc(Cl)cc12
• InChI: InChI=1S/C27H32ClN3O.2C24H28ClN3O2.C24H28ClN3O.C24H28FN3O.C23H27ClN4O/c1-2-22-24-16-20(28)9-11-25(24)30-26(22)27(32)29-13-12-19-8-10-21(17-23(19)18-6-7-18)31-14-4-3-5-15-31;2*1-2-19-20-14-17(25)8-11-21(20)27-23(19)24(30)26-15-22(29)16-6-9-18(10-7-16)28-12-4-3-5-13-28;1-2-20-21-16-18(25)8-11-22(21)27-23(20)24(29)26-13-12-17-6-9-19(10-7-17)28-14-4-3-5-15-28;1-2-20-21-11-8-18(25)16-22(21)27-23(20)24(29)26-13-12-17-6-9-19(10-7-17)28-14-4-3-5-15-28;1-2-19-20-14-16(24)6-9-21(20)27-22(19)23(29)25-11-10-17-7-8-18(15-26-17)28-12-4-3-5-13-28/h8-11,16-18,30H,2-7,12-15H2,1H3,(H,29,32);2*6-11,14,22,27,29H,2-5,12-13,15H2,1H3,(H,26,30);2*6-11,16,27H,2-5,12-15H2,1H3,(H,26,29);6-9,14-15,27H,2-5,10-13H2,1H3,(H,25,29)/t;2*22-;;;/m.10.../s1
• InChIKey: LDRPEQRQPVZMSB-UIEJEQTNSA-N
• XLogP: 30.82
• TPSA: 342.13 Ų
• H-Bond Donors: 14
• H-Bond Acceptors: 15
• Rotatable Bonds: 37
• Heavy Atoms: 179
• Complexity: —

Lipinski Rule of Five

4 violations

Rule	Value
MW ≤ 500	2516.36
LogP ≤ 5	30.82
H-Bond Donors ≤ 5	14
H-Bond Acceptors ≤ 10	15

Computed Properties (RDKit)

• Structural Alerts: {'alert_name': 'indol_3yl_alk(461)', 'substructure': 'N/A'}, {'alert_name': 'anil_di_alk_D(198)', 'substructure': 'N/A'}, {'alert_name': 'anil_di_alk_E(186)', 'substructure': 'N/A'}

Frequently Asked Questions

What is the IUPAC name of 5-chloro-N-[2-(2-cyclopropyl-4-piperidin-1-ylphenyl)ethyl]-3-ethyl-1H-indole-2-carboxamide;5-chloro-3-ethyl-N-[(2R)-2-hydroxy-2-(4-piperidin-1-ylphenyl)ethyl]-1H-indole-2-carboxamide;5-chloro-3-ethyl-N-[(2S)-2-hydroxy-2-(4-piperidin-1-ylphenyl)ethyl]-1H-indole-2-carboxamide;5-chloro-3-ethyl-N-[2-(4-piperidin-1-ylphenyl)ethyl]-1H-indole-2-carboxamide;5-chloro-3-ethyl-N-[2-(5-piperidin-1-yl-2-pyridinyl)ethyl]-1H-indole-2-carboxamide;3-ethyl-6-fluoro-N-[2-(4-piperidin-1-ylphenyl)ethyl]-1H-indole-2-carboxamide?

The IUPAC name of 5-chloro-N-[2-(2-cyclopropyl-4-piperidin-1-ylphenyl)ethyl]-3-ethyl-1H-indole-2-carboxamide;5-chloro-3-ethyl-N-[(2R)-2-hydroxy-2-(4-piperidin-1-ylphenyl)ethyl]-1H-indole-2-carboxamide;5-chloro-3-ethyl-N-[(2S)-2-hydroxy-2-(4-piperidin-1-ylphenyl)ethyl]-1H-indole-2-carboxamide;5-chloro-3-ethyl-N-[2-(4-piperidin-1-ylphenyl)ethyl]-1H-indole-2-carboxamide;5-chloro-3-ethyl-N-[2-(5-piperidin-1-yl-2-pyridinyl)ethyl]-1H-indole-2-carboxamide;3-ethyl-6-fluoro-N-[2-(4-piperidin-1-ylphenyl)ethyl]-1H-indole-2-carboxamide (CID 159320437) is 5-chloro-N-[2-(2-cyclopropyl-4-piperidin-1-ylphenyl)ethyl]-3-ethyl-1H-indole-2-carboxamide;5-chloro-3-ethyl-N-[(2R)-2-hydroxy-2-(4-piperidin-1-ylphenyl)ethyl]-1H-indole-2-carboxamide;5-chloro-3-ethyl-N-[(2S)-2-hydroxy-2-(4-piperidin-1-ylphenyl)ethyl]-1H-indole-2-carboxamide;5-chloro-3-ethyl-N-[2-(4-piperidin-1-ylphenyl)ethyl]-1H-indole-2-carboxamide;5-chloro-3-ethyl-N-[2-(5-piperidin-1-yl-2-pyridinyl)ethyl]-1H-indole-2-carboxamide;3-ethyl-6-fluoro-N-[2-(4-piperidin-1-ylphenyl)ethyl]-1H-indole-2-carboxamide.

What is the SMILES notation for 5-chloro-N-[2-(2-cyclopropyl-4-piperidin-1-ylphenyl)ethyl]-3-ethyl-1H-indole-2-carboxamide;5-chloro-3-ethyl-N-[(2R)-2-hydroxy-2-(4-piperidin-1-ylphenyl)ethyl]-1H-indole-2-carboxamide;5-chloro-3-ethyl-N-[(2S)-2-hydroxy-2-(4-piperidin-1-ylphenyl)ethyl]-1H-indole-2-carboxamide;5-chloro-3-ethyl-N-[2-(4-piperidin-1-ylphenyl)ethyl]-1H-indole-2-carboxamide;5-chloro-3-ethyl-N-[2-(5-piperidin-1-yl-2-pyridinyl)ethyl]-1H-indole-2-carboxamide;3-ethyl-6-fluoro-N-[2-(4-piperidin-1-ylphenyl)ethyl]-1H-indole-2-carboxamide?

The canonical SMILES for 5-chloro-N-[2-(2-cyclopropyl-4-piperidin-1-ylphenyl)ethyl]-3-ethyl-1H-indole-2-carboxamide;5-chloro-3-ethyl-N-[(2R)-2-hydroxy-2-(4-piperidin-1-ylphenyl)ethyl]-1H-indole-2-carboxamide;5-chloro-3-ethyl-N-[(2S)-2-hydroxy-2-(4-piperidin-1-ylphenyl)ethyl]-1H-indole-2-carboxamide;5-chloro-3-ethyl-N-[2-(4-piperidin-1-ylphenyl)ethyl]-1H-indole-2-carboxamide;5-chloro-3-ethyl-N-[2-(5-piperidin-1-yl-2-pyridinyl)ethyl]-1H-indole-2-carboxamide;3-ethyl-6-fluoro-N-[2-(4-piperidin-1-ylphenyl)ethyl]-1H-indole-2-carboxamide is CCc1c(C(=O)NCCc2ccc(N3CCCCC3)cc2)[nH]c2cc(F)ccc12.CCc1c(C(=O)NCCc2ccc(N3CCCCC3)cc2)[nH]c2ccc(Cl)cc12.CCc1c(C(=O)NCCc2ccc(N3CCCCC3)cc2C2CC2)[nH]c2ccc(Cl)cc12.CCc1c(C(=O)NCCc2ccc(N3CCCCC3)cn2)[nH]c2ccc(Cl)cc12.CCc1c(C(=O)NC[C@@H](O)c2ccc(N3CCCCC3)cc2)[nH]c2ccc(Cl)cc12.CCc1c(C(=O)NC[C@H](O)c2ccc(N3CCCCC3)cc2)[nH]c2ccc(Cl)cc12.

What is the InChIKey of 5-chloro-N-[2-(2-cyclopropyl-4-piperidin-1-ylphenyl)ethyl]-3-ethyl-1H-indole-2-carboxamide;5-chloro-3-ethyl-N-[(2R)-2-hydroxy-2-(4-piperidin-1-ylphenyl)ethyl]-1H-indole-2-carboxamide;5-chloro-3-ethyl-N-[(2S)-2-hydroxy-2-(4-piperidin-1-ylphenyl)ethyl]-1H-indole-2-carboxamide;5-chloro-3-ethyl-N-[2-(4-piperidin-1-ylphenyl)ethyl]-1H-indole-2-carboxamide;5-chloro-3-ethyl-N-[2-(5-piperidin-1-yl-2-pyridinyl)ethyl]-1H-indole-2-carboxamide;3-ethyl-6-fluoro-N-[2-(4-piperidin-1-ylphenyl)ethyl]-1H-indole-2-carboxamide?

The InChIKey is LDRPEQRQPVZMSB-UIEJEQTNSA-N. The full InChI is InChI=1S/C27H32ClN3O.2C24H28ClN3O2.C24H28ClN3O.C24H28FN3O.C23H27ClN4O/c1-2-22-24-16-20(28)9-11-25(24)30-26(22)27(32)29-13-12-19-8-10-21(17-23(19)18-6-7-18)31-14-4-3-5-15-31;2*1-2-19-20-14-17(25)8-11-21(20)27-23(19)24(30)26-15-22(29)16-6-9-18(10-7-16)28-12-4-3-5-13-28;1-2-20-21-16-18(25)8-11-22(21)27-23(20)24(29)26-13-12-17-6-9-19(10-7-17)28-14-4-3-5-15-28;1-2-20-21-11-8-18(25)16-22(21)27-23(20)24(29)26-13-12-17-6-9-19(10-7-17)28-14-4-3-5-15-28;1-2-19-20-14-16(24)6-9-21(20)27-22(19)23(29)25-11-10-17-7-8-18(15-26-17)28-12-4-3-5-13-28/h8-11,16-18,30H,2-7,12-15H2,1H3,(H,29,32);2*6-11,14,22,27,29H,2-5,12-13,15H2,1H3,(H,26,30);2*6-11,16,27H,2-5,12-15H2,1H3,(H,26,29);6-9,14-15,27H,2-5,10-13H2,1H3,(H,25,29)/t;2*22-;;;/m.10.../s1.

What are the key properties of 5-chloro-N-[2-(2-cyclopropyl-4-piperidin-1-ylphenyl)ethyl]-3-ethyl-1H-indole-2-carboxamide;5-chloro-3-ethyl-N-[(2R)-2-hydroxy-2-(4-piperidin-1-ylphenyl)ethyl]-1H-indole-2-carboxamide;5-chloro-3-ethyl-N-[(2S)-2-hydroxy-2-(4-piperidin-1-ylphenyl)ethyl]-1H-indole-2-carboxamide;5-chloro-3-ethyl-N-[2-(4-piperidin-1-ylphenyl)ethyl]-1H-indole-2-carboxamide;5-chloro-3-ethyl-N-[2-(5-piperidin-1-yl-2-pyridinyl)ethyl]-1H-indole-2-carboxamide;3-ethyl-6-fluoro-N-[2-(4-piperidin-1-ylphenyl)ethyl]-1H-indole-2-carboxamide?

5-chloro-N-[2-(2-cyclopropyl-4-piperidin-1-ylphenyl)ethyl]-3-ethyl-1H-indole-2-carboxamide;5-chloro-3-ethyl-N-[(2R)-2-hydroxy-2-(4-piperidin-1-ylphenyl)ethyl]-1H-indole-2-carboxamide;5-chloro-3-ethyl-N-[(2S)-2-hydroxy-2-(4-piperidin-1-ylphenyl)ethyl]-1H-indole-2-carboxamide;5-chloro-3-ethyl-N-[2-(4-piperidin-1-ylphenyl)ethyl]-1H-indole-2-carboxamide;5-chloro-3-ethyl-N-[2-(5-piperidin-1-yl-2-pyridinyl)ethyl]-1H-indole-2-carboxamide;3-ethyl-6-fluoro-N-[2-(4-piperidin-1-ylphenyl)ethyl]-1H-indole-2-carboxamide has a molecular weight of 2516.36 g/mol, XLogP of 30.82, 37 rotatable bonds, 14 hydrogen bond donors, and 15 hydrogen bond acceptors.

Where does this data come from?

All data for 5-chloro-N-[2-(2-cyclopropyl-4-piperidin-1-ylphenyl)ethyl]-3-ethyl-1H-indole-2-carboxamide;5-chloro-3-ethyl-N-[(2R)-2-hydroxy-2-(4-piperidin-1-ylphenyl)ethyl]-1H-indole-2-carboxamide;5-chloro-3-ethyl-N-[(2S)-2-hydroxy-2-(4-piperidin-1-ylphenyl)ethyl]-1H-indole-2-carboxamide;5-chloro-3-ethyl-N-[2-(4-piperidin-1-ylphenyl)ethyl]-1H-indole-2-carboxamide;5-chloro-3-ethyl-N-[2-(5-piperidin-1-yl-2-pyridinyl)ethyl]-1H-indole-2-carboxamide;3-ethyl-6-fluoro-N-[2-(4-piperidin-1-ylphenyl)ethyl]-1H-indole-2-carboxamide is sourced from PubChem (CID 159320437), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).