4-(2,6-difluorophenyl)-5-(1H-imidazol-2-yl)-2-(2-methylpyrazolo[1,5-a]pyridin-3-yl)-1,3-thiazole;4-(2-ethoxy-6-fluorophenyl)-5-(4H-imidazol-2-yl)-2-(2-methylpyrazolo[1,5-a]pyridin-3-yl)-1,3-thiazole;4-(2-fluorophenyl)-5-(4H-imidazol-2-yl)-2-[2-methyl-5-(2-piperidin-1-ylethoxy)pyrazolo[1,5-a]pyridin-3-yl]-1,3-thiazole;4-[3-[5-(4H-imidazol-2-yl)-4-phenyl-1,3-thiazol-2-yl]-2-methylpyrazolo[1,5-a]pyridin-5-yl]morpholine;2-[2-methyl-5-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-3-yl]-5-(4-methyl-1,2,4-triazol-3-yl)-4-phenyl-1,3-thiazole

C117H100F4N30O3S5 — CID 159331336

About 4-(2,6-difluorophenyl)-5-(1H-imidazol-2-yl)-2-(2-methylpyrazolo[1,5-a]pyridin-3-yl)-1,3-thiazole;4-(2-ethoxy-6-fluorophenyl)-5-(4H-imidazol-2-yl)-2-(2-methylpyrazolo[1,5-a]pyridin-3-yl)-1,3-thiazole;4-(2-fluorophenyl)-5-(4H-imidazol-2-yl)-2-[2-methyl-5-(2-piperidin-1-ylethoxy)pyrazolo[1,5-a]pyridin-3-yl]-1,3-thiazole;4-[3-[5-(4H-imidazol-2-yl)-4-phenyl-1,3-thiazol-2-yl]-2-methylpyrazolo[1,5-a]pyridin-5-yl]morpholine;2-[2-methyl-5-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-3-yl]-5-(4-methyl-1,2,4-triazol-3-yl)-4-phenyl-1,3-thiazole

4-(2,6-difluorophenyl)-5-(1H-imidazol-2-yl)-2-(2-methylpyrazolo[1,5-a]pyridin-3-yl)-1,3-thiazole;4-(2-ethoxy-6-fluorophenyl)-5-(4H-imidazol-2-yl)-2-(2-methylpyrazolo[1,5-a]pyridin-3-yl)-1,3-thiazole;4-(2-fluorophenyl)-5-(4H-imidazol-2-yl)-2-[2-methyl-5-(2-piperidin-1-ylethoxy)pyrazolo[1,5-a]pyridin-3-yl]-1,3-thiazole;4-[3-[5-(4H-imidazol-2-yl)-4-phenyl-1,3-thiazol-2-yl]-2-methylpyrazolo[1,5-a]pyridin-5-yl]morpholine;2-[2-methyl-5-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-3-yl]-5-(4-methyl-1,2,4-triazol-3-yl)-4-phenyl-1,3-thiazole (PubChem CID 159331336) has the molecular formula C117H100F4N30O3S5 and a molecular weight of 2210.62 g/mol. Its IUPAC name is 4-(2,6-difluorophenyl)-5-(1H-imidazol-2-yl)-2-(2-methylpyrazolo[1,5-a]pyridin-3-yl)-1,3-thiazole;4-(2-ethoxy-6-fluorophenyl)-5-(4H-imidazol-2-yl)-2-(2-methylpyrazolo[1,5-a]pyridin-3-yl)-1,3-thiazole;4-(2-fluorophenyl)-5-(4H-imidazol-2-yl)-2-[2-methyl-5-(2-piperidin-1-ylethoxy)pyrazolo[1,5-a]pyridin-3-yl]-1,3-thiazole;4-[3-[5-(4H-imidazol-2-yl)-4-phenyl-1,3-thiazol-2-yl]-2-methylpyrazolo[1,5-a]pyridin-5-yl]morpholine;2-[2-methyl-5-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-3-yl]-5-(4-methyl-1,2,4-triazol-3-yl)-4-phenyl-1,3-thiazole.

Molecular Properties

• Compound Name: 4-(2,6-difluorophenyl)-5-(1H-imidazol-2-yl)-2-(2-methylpyrazolo[1,5-a]pyridin-3-yl)-1,3-thiazole;4-(2-ethoxy-6-fluorophenyl)-5-(4H-imidazol-2-yl)-2-(2-methylpyrazolo[1,5-a]pyridin-3-yl)-1,3-thiazole;4-(2-fluorophenyl)-5-(4H-imidazol-2-yl)-2-[2-methyl-5-(2-piperidin-1-ylethoxy)pyrazolo[1,5-a]pyridin-3-yl]-1,3-thiazole;4-[3-[5-(4H-imidazol-2-yl)-4-phenyl-1,3-thiazol-2-yl]-2-methylpyrazolo[1,5-a]pyridin-5-yl]morpholine;2-[2-methyl-5-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-3-yl]-5-(4-methyl-1,2,4-triazol-3-yl)-4-phenyl-1,3-thiazole
• PubChem CID: 159331336
• Molecular Formula: C117H100F4N30O3S5
• Molecular Weight: 2210.62 g/mol
• Exact Mass: 2208.71
• IUPAC Name: 4-(2,6-difluorophenyl)-5-(1H-imidazol-2-yl)-2-(2-methylpyrazolo[1,5-a]pyridin-3-yl)-1,3-thiazole;4-(2-ethoxy-6-fluorophenyl)-5-(4H-imidazol-2-yl)-2-(2-methylpyrazolo[1,5-a]pyridin-3-yl)-1,3-thiazole;4-(2-fluorophenyl)-5-(4H-imidazol-2-yl)-2-[2-methyl-5-(2-piperidin-1-ylethoxy)pyrazolo[1,5-a]pyridin-3-yl]-1,3-thiazole;4-[3-[5-(4H-imidazol-2-yl)-4-phenyl-1,3-thiazol-2-yl]-2-methylpyrazolo[1,5-a]pyridin-5-yl]morpholine;2-[2-methyl-5-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-3-yl]-5-(4-methyl-1,2,4-triazol-3-yl)-4-phenyl-1,3-thiazole
• SMILES: CCOc1cccc(F)c1-c1nc(-c2c(C)nn3ccccc23)sc1C1=NCC=N1.Cc1nn2ccc(-c3cnn(C)c3)cc2c1-c1nc(-c2ccccc2)c(-c2nncn2C)s1.Cc1nn2ccc(N3CCOCC3)cc2c1-c1nc(-c2ccccc2)c(C2=NCC=N2)s1.Cc1nn2ccc(OCCN3CCCCC3)cc2c1-c1nc(-c2ccccc2F)c(C2=NCC=N2)s1.Cc1nn2ccccc2c1-c1nc(-c2c(F)cccc2F)c(-c2ncc[nH]2)s1
• InChI: InChI=1S/C27H27FN6OS.C24H20N8S.C24H22N6OS.C22H18FN5OS.C20H13F2N5S/c1-18-23(22-17-19(9-14-34(22)32-18)35-16-15-33-12-5-2-6-13-33)27-31-24(20-7-3-4-8-21(20)28)25(36-27)26-29-10-11-30-26;1-15-20(19-11-17(9-10-32(19)29-15)18-12-26-31(3)13-18)24-27-21(16-7-5-4-6-8-16)22(33-24)23-28-25-14-30(23)2;1-16-20(19-15-18(7-10-30(19)28-16)29-11-13-31-14-12-29)24-27-21(17-5-3-2-4-6-17)22(32-24)23-25-8-9-26-23;1-3-29-16-9-6-7-14(23)18(16)19-20(21-24-10-11-25-21)30-22(26-19)17-13(2)27-28-12-5-4-8-15(17)28;1-11-15(14-7-2-3-10-27(14)26-11)20-25-17(16-12(21)5-4-6-13(16)22)18(28-20)19-23-8-9-24-19/h3-4,7-10,14,17H,2,5-6,11-13,15-16H2,1H3;4-14H,1-3H3;2-8,10,15H,9,11-14H2,1H3;4-10,12H,3,11H2,1-2H3;2-10H,1H3,(H,23,24)
• InChIKey: LEZVGGOCNFFPFQ-UHFFFAOYSA-N
• XLogP: 23.90
• TPSA: 336.49 Ų
• H-Bond Donors: 1
• H-Bond Acceptors: 37
• Rotatable Bonds: 23
• Heavy Atoms: 159
• Complexity: —

Lipinski Rule of Five

3 violations

Rule	Value
MW ≤ 500	2210.62
LogP ≤ 5	23.90
H-Bond Donors ≤ 5	1
H-Bond Acceptors ≤ 10	37

Frequently Asked Questions

What is the IUPAC name of 4-(2,6-difluorophenyl)-5-(1H-imidazol-2-yl)-2-(2-methylpyrazolo[1,5-a]pyridin-3-yl)-1,3-thiazole;4-(2-ethoxy-6-fluorophenyl)-5-(4H-imidazol-2-yl)-2-(2-methylpyrazolo[1,5-a]pyridin-3-yl)-1,3-thiazole;4-(2-fluorophenyl)-5-(4H-imidazol-2-yl)-2-[2-methyl-5-(2-piperidin-1-ylethoxy)pyrazolo[1,5-a]pyridin-3-yl]-1,3-thiazole;4-[3-[5-(4H-imidazol-2-yl)-4-phenyl-1,3-thiazol-2-yl]-2-methylpyrazolo[1,5-a]pyridin-5-yl]morpholine;2-[2-methyl-5-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-3-yl]-5-(4-methyl-1,2,4-triazol-3-yl)-4-phenyl-1,3-thiazole?

The IUPAC name of 4-(2,6-difluorophenyl)-5-(1H-imidazol-2-yl)-2-(2-methylpyrazolo[1,5-a]pyridin-3-yl)-1,3-thiazole;4-(2-ethoxy-6-fluorophenyl)-5-(4H-imidazol-2-yl)-2-(2-methylpyrazolo[1,5-a]pyridin-3-yl)-1,3-thiazole;4-(2-fluorophenyl)-5-(4H-imidazol-2-yl)-2-[2-methyl-5-(2-piperidin-1-ylethoxy)pyrazolo[1,5-a]pyridin-3-yl]-1,3-thiazole;4-[3-[5-(4H-imidazol-2-yl)-4-phenyl-1,3-thiazol-2-yl]-2-methylpyrazolo[1,5-a]pyridin-5-yl]morpholine;2-[2-methyl-5-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-3-yl]-5-(4-methyl-1,2,4-triazol-3-yl)-4-phenyl-1,3-thiazole (CID 159331336) is 4-(2,6-difluorophenyl)-5-(1H-imidazol-2-yl)-2-(2-methylpyrazolo[1,5-a]pyridin-3-yl)-1,3-thiazole;4-(2-ethoxy-6-fluorophenyl)-5-(4H-imidazol-2-yl)-2-(2-methylpyrazolo[1,5-a]pyridin-3-yl)-1,3-thiazole;4-(2-fluorophenyl)-5-(4H-imidazol-2-yl)-2-[2-methyl-5-(2-piperidin-1-ylethoxy)pyrazolo[1,5-a]pyridin-3-yl]-1,3-thiazole;4-[3-[5-(4H-imidazol-2-yl)-4-phenyl-1,3-thiazol-2-yl]-2-methylpyrazolo[1,5-a]pyridin-5-yl]morpholine;2-[2-methyl-5-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-3-yl]-5-(4-methyl-1,2,4-triazol-3-yl)-4-phenyl-1,3-thiazole.

What is the SMILES notation for 4-(2,6-difluorophenyl)-5-(1H-imidazol-2-yl)-2-(2-methylpyrazolo[1,5-a]pyridin-3-yl)-1,3-thiazole;4-(2-ethoxy-6-fluorophenyl)-5-(4H-imidazol-2-yl)-2-(2-methylpyrazolo[1,5-a]pyridin-3-yl)-1,3-thiazole;4-(2-fluorophenyl)-5-(4H-imidazol-2-yl)-2-[2-methyl-5-(2-piperidin-1-ylethoxy)pyrazolo[1,5-a]pyridin-3-yl]-1,3-thiazole;4-[3-[5-(4H-imidazol-2-yl)-4-phenyl-1,3-thiazol-2-yl]-2-methylpyrazolo[1,5-a]pyridin-5-yl]morpholine;2-[2-methyl-5-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-3-yl]-5-(4-methyl-1,2,4-triazol-3-yl)-4-phenyl-1,3-thiazole?

The canonical SMILES for 4-(2,6-difluorophenyl)-5-(1H-imidazol-2-yl)-2-(2-methylpyrazolo[1,5-a]pyridin-3-yl)-1,3-thiazole;4-(2-ethoxy-6-fluorophenyl)-5-(4H-imidazol-2-yl)-2-(2-methylpyrazolo[1,5-a]pyridin-3-yl)-1,3-thiazole;4-(2-fluorophenyl)-5-(4H-imidazol-2-yl)-2-[2-methyl-5-(2-piperidin-1-ylethoxy)pyrazolo[1,5-a]pyridin-3-yl]-1,3-thiazole;4-[3-[5-(4H-imidazol-2-yl)-4-phenyl-1,3-thiazol-2-yl]-2-methylpyrazolo[1,5-a]pyridin-5-yl]morpholine;2-[2-methyl-5-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-3-yl]-5-(4-methyl-1,2,4-triazol-3-yl)-4-phenyl-1,3-thiazole is CCOc1cccc(F)c1-c1nc(-c2c(C)nn3ccccc23)sc1C1=NCC=N1.Cc1nn2ccc(-c3cnn(C)c3)cc2c1-c1nc(-c2ccccc2)c(-c2nncn2C)s1.Cc1nn2ccc(N3CCOCC3)cc2c1-c1nc(-c2ccccc2)c(C2=NCC=N2)s1.Cc1nn2ccc(OCCN3CCCCC3)cc2c1-c1nc(-c2ccccc2F)c(C2=NCC=N2)s1.Cc1nn2ccccc2c1-c1nc(-c2c(F)cccc2F)c(-c2ncc[nH]2)s1.

What is the InChIKey of 4-(2,6-difluorophenyl)-5-(1H-imidazol-2-yl)-2-(2-methylpyrazolo[1,5-a]pyridin-3-yl)-1,3-thiazole;4-(2-ethoxy-6-fluorophenyl)-5-(4H-imidazol-2-yl)-2-(2-methylpyrazolo[1,5-a]pyridin-3-yl)-1,3-thiazole;4-(2-fluorophenyl)-5-(4H-imidazol-2-yl)-2-[2-methyl-5-(2-piperidin-1-ylethoxy)pyrazolo[1,5-a]pyridin-3-yl]-1,3-thiazole;4-[3-[5-(4H-imidazol-2-yl)-4-phenyl-1,3-thiazol-2-yl]-2-methylpyrazolo[1,5-a]pyridin-5-yl]morpholine;2-[2-methyl-5-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-3-yl]-5-(4-methyl-1,2,4-triazol-3-yl)-4-phenyl-1,3-thiazole?

The InChIKey is LEZVGGOCNFFPFQ-UHFFFAOYSA-N. The full InChI is InChI=1S/C27H27FN6OS.C24H20N8S.C24H22N6OS.C22H18FN5OS.C20H13F2N5S/c1-18-23(22-17-19(9-14-34(22)32-18)35-16-15-33-12-5-2-6-13-33)27-31-24(20-7-3-4-8-21(20)28)25(36-27)26-29-10-11-30-26;1-15-20(19-11-17(9-10-32(19)29-15)18-12-26-31(3)13-18)24-27-21(16-7-5-4-6-8-16)22(33-24)23-28-25-14-30(23)2;1-16-20(19-15-18(7-10-30(19)28-16)29-11-13-31-14-12-29)24-27-21(17-5-3-2-4-6-17)22(32-24)23-25-8-9-26-23;1-3-29-16-9-6-7-14(23)18(16)19-20(21-24-10-11-25-21)30-22(26-19)17-13(2)27-28-12-5-4-8-15(17)28;1-11-15(14-7-2-3-10-27(14)26-11)20-25-17(16-12(21)5-4-6-13(16)22)18(28-20)19-23-8-9-24-19/h3-4,7-10,14,17H,2,5-6,11-13,15-16H2,1H3;4-14H,1-3H3;2-8,10,15H,9,11-14H2,1H3;4-10,12H,3,11H2,1-2H3;2-10H,1H3,(H,23,24).

What are the key properties of 4-(2,6-difluorophenyl)-5-(1H-imidazol-2-yl)-2-(2-methylpyrazolo[1,5-a]pyridin-3-yl)-1,3-thiazole;4-(2-ethoxy-6-fluorophenyl)-5-(4H-imidazol-2-yl)-2-(2-methylpyrazolo[1,5-a]pyridin-3-yl)-1,3-thiazole;4-(2-fluorophenyl)-5-(4H-imidazol-2-yl)-2-[2-methyl-5-(2-piperidin-1-ylethoxy)pyrazolo[1,5-a]pyridin-3-yl]-1,3-thiazole;4-[3-[5-(4H-imidazol-2-yl)-4-phenyl-1,3-thiazol-2-yl]-2-methylpyrazolo[1,5-a]pyridin-5-yl]morpholine;2-[2-methyl-5-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-3-yl]-5-(4-methyl-1,2,4-triazol-3-yl)-4-phenyl-1,3-thiazole?

4-(2,6-difluorophenyl)-5-(1H-imidazol-2-yl)-2-(2-methylpyrazolo[1,5-a]pyridin-3-yl)-1,3-thiazole;4-(2-ethoxy-6-fluorophenyl)-5-(4H-imidazol-2-yl)-2-(2-methylpyrazolo[1,5-a]pyridin-3-yl)-1,3-thiazole;4-(2-fluorophenyl)-5-(4H-imidazol-2-yl)-2-[2-methyl-5-(2-piperidin-1-ylethoxy)pyrazolo[1,5-a]pyridin-3-yl]-1,3-thiazole;4-[3-[5-(4H-imidazol-2-yl)-4-phenyl-1,3-thiazol-2-yl]-2-methylpyrazolo[1,5-a]pyridin-5-yl]morpholine;2-[2-methyl-5-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-3-yl]-5-(4-methyl-1,2,4-triazol-3-yl)-4-phenyl-1,3-thiazole has a molecular weight of 2210.62 g/mol, XLogP of 23.90, 23 rotatable bonds, 1 hydrogen bond donors, and 37 hydrogen bond acceptors.

Where does this data come from?

All data for 4-(2,6-difluorophenyl)-5-(1H-imidazol-2-yl)-2-(2-methylpyrazolo[1,5-a]pyridin-3-yl)-1,3-thiazole;4-(2-ethoxy-6-fluorophenyl)-5-(4H-imidazol-2-yl)-2-(2-methylpyrazolo[1,5-a]pyridin-3-yl)-1,3-thiazole;4-(2-fluorophenyl)-5-(4H-imidazol-2-yl)-2-[2-methyl-5-(2-piperidin-1-ylethoxy)pyrazolo[1,5-a]pyridin-3-yl]-1,3-thiazole;4-[3-[5-(4H-imidazol-2-yl)-4-phenyl-1,3-thiazol-2-yl]-2-methylpyrazolo[1,5-a]pyridin-5-yl]morpholine;2-[2-methyl-5-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-3-yl]-5-(4-methyl-1,2,4-triazol-3-yl)-4-phenyl-1,3-thiazole is sourced from PubChem (CID 159331336), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).