N-[(2S)-1-amino-1-oxopropan-2-yl]-6-methoxy-3-naphthalen-2-yl-1H-indazole-5-carboxamide;N-(cyclopropylmethyl)-6-methoxy-3-naphthalen-2-yl-1H-indazole-5-carboxamide;N-[(2S)-1-hydroxy-3-methylbutan-2-yl]-6-methoxy-3-naphthalen-2-yl-1H-indazole-5-carboxamide;N-[(1S)-2-hydroxy-1-phenylethyl]-6-methoxy-3-naphthalen-2-yl-1H-indazole-5-carboxamide;6-methoxy-3-naphthalen-2-yl-N-(thiophen-2-ylmethyl)-1H-indazole-5-carboxamide

C120H108N16O13S — CID 159337959

IUPACN-[(2S)-1-amino-1-oxopropan-2-yl]-6-methoxy-3-naphthalen-2-yl-1H-indazole-5-carboxamide;N-(cyclopropylmethyl)-6-methoxy-3-naphthalen-2-yl-1H-indazole-5-carboxamide;N-[(2S)-1-hydroxy-3-methylbutan-2-yl]-6-methoxy-3-naphthalen-2-yl-1H-indazole-5-carboxamide;N-[(1S)-2-hydroxy-1-phenylethyl]-6-methoxy-3-naphthalen-2-yl-1H-indazole-5-carboxamide;6-methoxy-3-naphthalen-2-yl-N-(thiophen-2-ylmethyl)-1H-indazole-5-carboxamide
SMILESCOc1cc2[nH]nc(-c3ccc4ccccc4c3)c2cc1C(=O)NCC1CC1.COc1cc2[nH]nc(-c3ccc4ccccc4c3)c2cc1C(=O)NCc1cccs1.COc1cc2[nH]nc(-c3ccc4ccccc4c3)c2cc1C(=O)N[C@@H](C)C(N)=O.COc1cc2[nH]nc(-c3ccc4ccccc4c3)c2cc1C(=O)N[C@H](CO)C(C)C.COc1cc2[nH]nc(-c3ccc4ccccc4c3)c2cc1C(=O)N[C@H](CO)c1ccccc1
InChIInChI=1S/C27H23N3O3.C24H25N3O3.C24H19N3O2S.C23H21N3O2.C22H20N4O3/c1-33-25-15-23-21(14-22(25)27(32)28-24(16-31)18-8-3-2-4-9-18)26(30-29-23)20-12-11-17-7-5-6-10-19(17)13-20;1-14(2)21(13-28)25-24(29)19-11-18-20(12-22(19)30-3)26-27-23(18)17-9-8-15-6-4-5-7-16(15)10-17;1-29-22-13-21-19(12-20(22)24(28)25-14-18-7-4-10-30-18)23(27-26-21)17-9-8-15-5-2-3-6-16(15)11-17;1-28-21-12-20-18(11-19(21)23(27)24-13-14-6-7-14)22(26-25-20)17-9-8-15-4-2-3-5-16(15)10-17;1-12(21(23)27)24-22(28)17-10-16-18(11-19(17)29-2)25-26-20(16)15-8-7-13-5-3-4-6-14(13)9-15/h2-15,24,31H,16H2,1H3,(H,28,32)(H,29,30);4-12,14,21,28H,13H2,1-3H3,(H,25,29)(H,26,27);2-13H,14H2,1H3,(H,25,28)(H,26,27);2-5,8-12,14H,6-7,13H2,1H3,(H,24,27)(H,25,26);3-12H,1-2H3,(H2,23,27)(H,24,28)(H,25,26)/t24-;21-;;;12-/m11..0/s1
InChIKeyLFTZIMHERCEIOM-AWLKYZGRSA-N
MW2014.35 g/mol
LogP21.90
Rot. Bonds27

About N-[(2S)-1-amino-1-oxopropan-2-yl]-6-methoxy-3-naphthalen-2-yl-1H-indazole-5-carboxamide;N-(cyclopropylmethyl)-6-methoxy-3-naphthalen-2-yl-1H-indazole-5-carboxamide;N-[(2S)-1-hydroxy-3-methylbutan-2-yl]-6-methoxy-3-naphthalen-2-yl-1H-indazole-5-carboxamide;N-[(1S)-2-hydroxy-1-phenylethyl]-6-methoxy-3-naphthalen-2-yl-1H-indazole-5-carboxamide;6-methoxy-3-naphthalen-2-yl-N-(thiophen-2-ylmethyl)-1H-indazole-5-carboxamide

N-[(2S)-1-amino-1-oxopropan-2-yl]-6-methoxy-3-naphthalen-2-yl-1H-indazole-5-carboxamide;N-(cyclopropylmethyl)-6-methoxy-3-naphthalen-2-yl-1H-indazole-5-carboxamide;N-[(2S)-1-hydroxy-3-methylbutan-2-yl]-6-methoxy-3-naphthalen-2-yl-1H-indazole-5-carboxamide;N-[(1S)-2-hydroxy-1-phenylethyl]-6-methoxy-3-naphthalen-2-yl-1H-indazole-5-carboxamide;6-methoxy-3-naphthalen-2-yl-N-(thiophen-2-ylmethyl)-1H-indazole-5-carboxamide (PubChem CID 159337959) has the molecular formula C120H108N16O13S and a molecular weight of 2014.35 g/mol. Its IUPAC name is N-[(2S)-1-amino-1-oxopropan-2-yl]-6-methoxy-3-naphthalen-2-yl-1H-indazole-5-carboxamide;N-(cyclopropylmethyl)-6-methoxy-3-naphthalen-2-yl-1H-indazole-5-carboxamide;N-[(2S)-1-hydroxy-3-methylbutan-2-yl]-6-methoxy-3-naphthalen-2-yl-1H-indazole-5-carboxamide;N-[(1S)-2-hydroxy-1-phenylethyl]-6-methoxy-3-naphthalen-2-yl-1H-indazole-5-carboxamide;6-methoxy-3-naphthalen-2-yl-N-(thiophen-2-ylmethyl)-1H-indazole-5-carboxamide.

Molecular Properties

Compound NameN-[(2S)-1-amino-1-oxopropan-2-yl]-6-methoxy-3-naphthalen-2-yl-1H-indazole-5-carboxamide;N-(cyclopropylmethyl)-6-methoxy-3-naphthalen-2-yl-1H-indazole-5-carboxamide;N-[(2S)-1-hydroxy-3-methylbutan-2-yl]-6-methoxy-3-naphthalen-2-yl-1H-indazole-5-carboxamide;N-[(1S)-2-hydroxy-1-phenylethyl]-6-methoxy-3-naphthalen-2-yl-1H-indazole-5-carboxamide;6-methoxy-3-naphthalen-2-yl-N-(thiophen-2-ylmethyl)-1H-indazole-5-carboxamide
PubChem CID159337959
Molecular FormulaC120H108N16O13S
Molecular Weight2014.35 g/mol
Exact Mass2012.80
IUPAC NameN-[(2S)-1-amino-1-oxopropan-2-yl]-6-methoxy-3-naphthalen-2-yl-1H-indazole-5-carboxamide;N-(cyclopropylmethyl)-6-methoxy-3-naphthalen-2-yl-1H-indazole-5-carboxamide;N-[(2S)-1-hydroxy-3-methylbutan-2-yl]-6-methoxy-3-naphthalen-2-yl-1H-indazole-5-carboxamide;N-[(1S)-2-hydroxy-1-phenylethyl]-6-methoxy-3-naphthalen-2-yl-1H-indazole-5-carboxamide;6-methoxy-3-naphthalen-2-yl-N-(thiophen-2-ylmethyl)-1H-indazole-5-carboxamide
SMILESCOc1cc2[nH]nc(-c3ccc4ccccc4c3)c2cc1C(=O)NCC1CC1.COc1cc2[nH]nc(-c3ccc4ccccc4c3)c2cc1C(=O)NCc1cccs1.COc1cc2[nH]nc(-c3ccc4ccccc4c3)c2cc1C(=O)N[C@@H](C)C(N)=O.COc1cc2[nH]nc(-c3ccc4ccccc4c3)c2cc1C(=O)N[C@H](CO)C(C)C.COc1cc2[nH]nc(-c3ccc4ccccc4c3)c2cc1C(=O)N[C@H](CO)c1ccccc1
InChIInChI=1S/C27H23N3O3.C24H25N3O3.C24H19N3O2S.C23H21N3O2.C22H20N4O3/c1-33-25-15-23-21(14-22(25)27(32)28-24(16-31)18-8-3-2-4-9-18)26(30-29-23)20-12-11-17-7-5-6-10-19(17)13-20;1-14(2)21(13-28)25-24(29)19-11-18-20(12-22(19)30-3)26-27-23(18)17-9-8-15-6-4-5-7-16(15)10-17;1-29-22-13-21-19(12-20(22)24(28)25-14-18-7-4-10-30-18)23(27-26-21)17-9-8-15-5-2-3-6-16(15)11-17;1-28-21-12-20-18(11-19(21)23(27)24-13-14-6-7-14)22(26-25-20)17-9-8-15-4-2-3-5-16(15)10-17;1-12(21(23)27)24-22(28)17-10-16-18(11-19(17)29-2)25-26-20(16)15-8-7-13-5-3-4-6-14(13)9-15/h2-15,24,31H,16H2,1H3,(H,28,32)(H,29,30);4-12,14,21,28H,13H2,1-3H3,(H,25,29)(H,26,27);2-13H,14H2,1H3,(H,25,28)(H,26,27);2-5,8-12,14H,6-7,13H2,1H3,(H,24,27)(H,25,26);3-12H,1-2H3,(H2,23,27)(H,24,28)(H,25,26)/t24-;21-;;;12-/m11..0/s1
InChIKeyLFTZIMHERCEIOM-AWLKYZGRSA-N
XLogP21.90
TPSA418.60 Ų
H-Bond Donors13
H-Bond Acceptors19
Rotatable Bonds27
Heavy Atoms150
Complexity—

Lipinski Rule of Five

4 violations

RuleValue
MW ≤ 5002014.35
LogP ≤ 521.90
H-Bond Donors ≤ 513
H-Bond Acceptors ≤ 1019

Analyze N-[(2S)-1-amino-1-oxopropan-2-yl]-6-methoxy-3-naphthalen-2-yl-1H-indazole-5-carboxamide;N-(cyclopropylmethyl)-6-methoxy-3-naphthalen-2-yl-1H-indazole-5-carboxamide;N-[(2S)-1-hydroxy-3-methylbutan-2-yl]-6-methoxy-3-naphthalen-2-yl-1H-indazole-5-carboxamide;N-[(1S)-2-hydroxy-1-phenylethyl]-6-methoxy-3-naphthalen-2-yl-1H-indazole-5-carboxamide;6-methoxy-3-naphthalen-2-yl-N-(thiophen-2-ylmethyl)-1H-indazole-5-carboxamide with MolForge

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Related Compounds

N-cyclopropyl-3-[(E)-2-[3-(hydroxymethyl)phenyl]ethenyl]-4-methoxy-2H-indazole-5-carboxamide;N-cyclopropyl-4-methoxy-3-[(E)-2-(2-methoxyphenyl)ethenyl]-2H-indazole-5-carboxamide;N-cyclopropyl-4-methoxy-3-[(E)-2-(3-methoxyphenyl)ethenyl]-2H-indazole-5-carboxamide;N-cyclopropyl-4-methoxy-3-[(E)-2-(4-methoxyphenyl)ethenyl]-2H-indazole-5-carboxamide;7-fluoro-N-[(1S)-2-hydroxy-1-phenylethyl]-3-[(E)-2-[4-(trifluoromethyl)phenyl]ethenyl]-2H-indazole-5-carboxamide
CID 160081203
N-cyclopropyl-3-[(E)-2-[4-(hydroxymethyl)phenyl]ethenyl]-4-methoxy-2H-indazole-5-carboxamide;N-cyclopropyl-4-methoxy-3-[(E)-2-(2-methoxyphenyl)ethenyl]-2H-indazole-5-carboxamide;N-cyclopropyl-4-methoxy-3-[(E)-2-(3-methoxyphenyl)ethenyl]-2H-indazole-5-carboxamide;N-cyclopropyl-4-methoxy-3-[(E)-2-(4-methoxyphenyl)ethenyl]-2H-indazole-5-carboxamide;7-fluoro-N-[(1S)-2-hydroxy-1-phenylethyl]-3-[(E)-2-[4-(trifluoromethyl)phenyl]ethenyl]-2H-indazole-5-carboxamide
CID 160581110
N-cyclopropyl-3-[(E)-2-[2-(hydroxymethyl)phenyl]ethenyl]-4-methoxy-2H-indazole-5-carboxamide;N-cyclopropyl-3-[(E)-2-[3-(hydroxymethyl)phenyl]ethenyl]-4-methoxy-2H-indazole-5-carboxamide;N-cyclopropyl-4-methoxy-3-[(E)-2-(2-methoxyphenyl)ethenyl]-2H-indazole-5-carboxamide;7-fluoro-N-[(1S)-2-hydroxy-1-phenylethyl]-3-[(E)-2-[4-(trifluoromethyl)phenyl]ethenyl]-2H-indazole-5-carboxamide
CID 160923552
3-(1-benzothiophen-2-yl)-N-(1-hydroxy-3-methylbutan-2-yl)-6-methoxy-1H-indazole-5-carboxamide
CID 23589769
4-methoxy-3-naphthalen-2-yl-N-(2-thiophen-2-ylethyl)-1H-indazole-5-carboxamide
CID 23589805
4-methoxy-3-naphthalen-2-yl-N-(thiophen-2-ylmethyl)-1H-indazole-5-carboxamide
CID 23589808
6-methoxy-3-naphthalen-2-yl-N-(thiophen-2-ylmethyl)-1H-indazole-5-carboxamide
CID 23589828
3-(1-benzothiophen-2-yl)-N-[(2S)-1-hydroxy-3-methylbutan-2-yl]-6-methoxy-1H-indazole-5-carboxamide
CID 58582181
3-(1-benzothiophen-2-yl)-N-[(1S)-2-hydroxy-1-phenylethyl]-6-methoxy-1H-indazole-5-carboxamide
CID 58582225
4-methoxy-3-naphthalen-2-yl-N-(2-thiophen-2-ylethyl)-2H-indazole-5-carboxamide
CID 135617771
N-cyclopropyl-3-[(E)-2-[4-(2-hydroxyethyl)phenyl]ethenyl]-4-methoxy-2H-indazole-5-carboxamide;N-cyclopropyl-3-[(E)-2-[4-(hydroxymethyl)phenyl]ethenyl]-4-methoxy-2H-indazole-5-carboxamide;N-cyclopropyl-4-methoxy-3-[(E)-2-(3-methoxyphenyl)ethenyl]-2H-indazole-5-carboxamide;N-cyclopropyl-4-methoxy-3-[(E)-2-(4-methoxyphenyl)ethenyl]-2H-indazole-5-carboxamide
CID 157248359
N-cyclopropyl-4-methoxy-3-[(E)-2-thiophen-2-ylethenyl]-2H-indazole-5-carboxamide;N-(furan-2-ylmethyl)-4-methoxy-3-[(E)-2-thiophen-2-ylethenyl]-2H-indazole-5-carboxamide;N-(1-hydroxy-3-methylbutan-2-yl)-4-methoxy-3-[(E)-2-thiophen-2-ylethenyl]-2H-indazole-5-carboxamide;N-(2-hydroxy-1-phenylethyl)-4-methoxy-3-[(E)-2-thiophen-2-ylethenyl]-2H-indazole-5-carboxamide;4-methoxy-3-[(E)-2-thiophen-2-ylethenyl]-2H-indazole-5-carboxylic acid;4-methoxy-3-[(E)-2-thiophen-2-ylethenyl]-N-(thiophen-2-ylmethyl)-2H-indazole-5-carboxamide
CID 157442797

Frequently Asked Questions

What is the IUPAC name of N-[(2S)-1-amino-1-oxopropan-2-yl]-6-methoxy-3-naphthalen-2-yl-1H-indazole-5-carboxamide;N-(cyclopropylmethyl)-6-methoxy-3-naphthalen-2-yl-1H-indazole-5-carboxamide;N-[(2S)-1-hydroxy-3-methylbutan-2-yl]-6-methoxy-3-naphthalen-2-yl-1H-indazole-5-carboxamide;N-[(1S)-2-hydroxy-1-phenylethyl]-6-methoxy-3-naphthalen-2-yl-1H-indazole-5-carboxamide;6-methoxy-3-naphthalen-2-yl-N-(thiophen-2-ylmethyl)-1H-indazole-5-carboxamide?
The IUPAC name of N-[(2S)-1-amino-1-oxopropan-2-yl]-6-methoxy-3-naphthalen-2-yl-1H-indazole-5-carboxamide;N-(cyclopropylmethyl)-6-methoxy-3-naphthalen-2-yl-1H-indazole-5-carboxamide;N-[(2S)-1-hydroxy-3-methylbutan-2-yl]-6-methoxy-3-naphthalen-2-yl-1H-indazole-5-carboxamide;N-[(1S)-2-hydroxy-1-phenylethyl]-6-methoxy-3-naphthalen-2-yl-1H-indazole-5-carboxamide;6-methoxy-3-naphthalen-2-yl-N-(thiophen-2-ylmethyl)-1H-indazole-5-carboxamide (CID 159337959) is N-[(2S)-1-amino-1-oxopropan-2-yl]-6-methoxy-3-naphthalen-2-yl-1H-indazole-5-carboxamide;N-(cyclopropylmethyl)-6-methoxy-3-naphthalen-2-yl-1H-indazole-5-carboxamide;N-[(2S)-1-hydroxy-3-methylbutan-2-yl]-6-methoxy-3-naphthalen-2-yl-1H-indazole-5-carboxamide;N-[(1S)-2-hydroxy-1-phenylethyl]-6-methoxy-3-naphthalen-2-yl-1H-indazole-5-carboxamide;6-methoxy-3-naphthalen-2-yl-N-(thiophen-2-ylmethyl)-1H-indazole-5-carboxamide.
What is the SMILES notation for N-[(2S)-1-amino-1-oxopropan-2-yl]-6-methoxy-3-naphthalen-2-yl-1H-indazole-5-carboxamide;N-(cyclopropylmethyl)-6-methoxy-3-naphthalen-2-yl-1H-indazole-5-carboxamide;N-[(2S)-1-hydroxy-3-methylbutan-2-yl]-6-methoxy-3-naphthalen-2-yl-1H-indazole-5-carboxamide;N-[(1S)-2-hydroxy-1-phenylethyl]-6-methoxy-3-naphthalen-2-yl-1H-indazole-5-carboxamide;6-methoxy-3-naphthalen-2-yl-N-(thiophen-2-ylmethyl)-1H-indazole-5-carboxamide?
The canonical SMILES for N-[(2S)-1-amino-1-oxopropan-2-yl]-6-methoxy-3-naphthalen-2-yl-1H-indazole-5-carboxamide;N-(cyclopropylmethyl)-6-methoxy-3-naphthalen-2-yl-1H-indazole-5-carboxamide;N-[(2S)-1-hydroxy-3-methylbutan-2-yl]-6-methoxy-3-naphthalen-2-yl-1H-indazole-5-carboxamide;N-[(1S)-2-hydroxy-1-phenylethyl]-6-methoxy-3-naphthalen-2-yl-1H-indazole-5-carboxamide;6-methoxy-3-naphthalen-2-yl-N-(thiophen-2-ylmethyl)-1H-indazole-5-carboxamide is COc1cc2[nH]nc(-c3ccc4ccccc4c3)c2cc1C(=O)NCC1CC1.COc1cc2[nH]nc(-c3ccc4ccccc4c3)c2cc1C(=O)NCc1cccs1.COc1cc2[nH]nc(-c3ccc4ccccc4c3)c2cc1C(=O)N[C@@H](C)C(N)=O.COc1cc2[nH]nc(-c3ccc4ccccc4c3)c2cc1C(=O)N[C@H](CO)C(C)C.COc1cc2[nH]nc(-c3ccc4ccccc4c3)c2cc1C(=O)N[C@H](CO)c1ccccc1.
What is the InChIKey of N-[(2S)-1-amino-1-oxopropan-2-yl]-6-methoxy-3-naphthalen-2-yl-1H-indazole-5-carboxamide;N-(cyclopropylmethyl)-6-methoxy-3-naphthalen-2-yl-1H-indazole-5-carboxamide;N-[(2S)-1-hydroxy-3-methylbutan-2-yl]-6-methoxy-3-naphthalen-2-yl-1H-indazole-5-carboxamide;N-[(1S)-2-hydroxy-1-phenylethyl]-6-methoxy-3-naphthalen-2-yl-1H-indazole-5-carboxamide;6-methoxy-3-naphthalen-2-yl-N-(thiophen-2-ylmethyl)-1H-indazole-5-carboxamide?
The InChIKey is LFTZIMHERCEIOM-AWLKYZGRSA-N. The full InChI is InChI=1S/C27H23N3O3.C24H25N3O3.C24H19N3O2S.C23H21N3O2.C22H20N4O3/c1-33-25-15-23-21(14-22(25)27(32)28-24(16-31)18-8-3-2-4-9-18)26(30-29-23)20-12-11-17-7-5-6-10-19(17)13-20;1-14(2)21(13-28)25-24(29)19-11-18-20(12-22(19)30-3)26-27-23(18)17-9-8-15-6-4-5-7-16(15)10-17;1-29-22-13-21-19(12-20(22)24(28)25-14-18-7-4-10-30-18)23(27-26-21)17-9-8-15-5-2-3-6-16(15)11-17;1-28-21-12-20-18(11-19(21)23(27)24-13-14-6-7-14)22(26-25-20)17-9-8-15-4-2-3-5-16(15)10-17;1-12(21(23)27)24-22(28)17-10-16-18(11-19(17)29-2)25-26-20(16)15-8-7-13-5-3-4-6-14(13)9-15/h2-15,24,31H,16H2,1H3,(H,28,32)(H,29,30);4-12,14,21,28H,13H2,1-3H3,(H,25,29)(H,26,27);2-13H,14H2,1H3,(H,25,28)(H,26,27);2-5,8-12,14H,6-7,13H2,1H3,(H,24,27)(H,25,26);3-12H,1-2H3,(H2,23,27)(H,24,28)(H,25,26)/t24-;21-;;;12-/m11..0/s1.
What are the key properties of N-[(2S)-1-amino-1-oxopropan-2-yl]-6-methoxy-3-naphthalen-2-yl-1H-indazole-5-carboxamide;N-(cyclopropylmethyl)-6-methoxy-3-naphthalen-2-yl-1H-indazole-5-carboxamide;N-[(2S)-1-hydroxy-3-methylbutan-2-yl]-6-methoxy-3-naphthalen-2-yl-1H-indazole-5-carboxamide;N-[(1S)-2-hydroxy-1-phenylethyl]-6-methoxy-3-naphthalen-2-yl-1H-indazole-5-carboxamide;6-methoxy-3-naphthalen-2-yl-N-(thiophen-2-ylmethyl)-1H-indazole-5-carboxamide?
N-[(2S)-1-amino-1-oxopropan-2-yl]-6-methoxy-3-naphthalen-2-yl-1H-indazole-5-carboxamide;N-(cyclopropylmethyl)-6-methoxy-3-naphthalen-2-yl-1H-indazole-5-carboxamide;N-[(2S)-1-hydroxy-3-methylbutan-2-yl]-6-methoxy-3-naphthalen-2-yl-1H-indazole-5-carboxamide;N-[(1S)-2-hydroxy-1-phenylethyl]-6-methoxy-3-naphthalen-2-yl-1H-indazole-5-carboxamide;6-methoxy-3-naphthalen-2-yl-N-(thiophen-2-ylmethyl)-1H-indazole-5-carboxamide has a molecular weight of 2014.35 g/mol, XLogP of 21.90, 27 rotatable bonds, 13 hydrogen bond donors, and 19 hydrogen bond acceptors.
Where does this data come from?
All data for N-[(2S)-1-amino-1-oxopropan-2-yl]-6-methoxy-3-naphthalen-2-yl-1H-indazole-5-carboxamide;N-(cyclopropylmethyl)-6-methoxy-3-naphthalen-2-yl-1H-indazole-5-carboxamide;N-[(2S)-1-hydroxy-3-methylbutan-2-yl]-6-methoxy-3-naphthalen-2-yl-1H-indazole-5-carboxamide;N-[(1S)-2-hydroxy-1-phenylethyl]-6-methoxy-3-naphthalen-2-yl-1H-indazole-5-carboxamide;6-methoxy-3-naphthalen-2-yl-N-(thiophen-2-ylmethyl)-1H-indazole-5-carboxamide is sourced from PubChem (CID 159337959), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).