1-N-[3-(1-benzothiophen-2-yl)imidazo[1,2-a]pyrazin-8-yl]-3-N,3-N-dimethylbenzene-1,3-diamine;N-cyclohexyl-3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-amine;1-ethyl-3-[3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]urea;1-[3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]-3-phenylurea;N-[3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]pyridine-3-carboxamide;3-(1-methylpyrazol-4-yl)-N-(2-morpholin-4-ylethyl)imidazo[1,2-a]pyrazin-8-amine;3-(1-methylpyrazol-4-yl)-N-(piperidin-4-ylmethyl)imidazo[1,2-a]pyrazin-8-amine;3-(1-methylpyrazol-4-yl)-N-(pyrrolidin-3-ylmethyl)imidazo[1,2-a]pyrazin-8-amine

C131H143N53O4S — CID 159344670

IUPAC1-N-[3-(1-benzothiophen-2-yl)imidazo[1,2-a]pyrazin-8-yl]-3-N,3-N-dimethylbenzene-1,3-diamine;N-cyclohexyl-3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-amine;1-ethyl-3-[3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]urea;1-[3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]-3-phenylurea;N-[3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]pyridine-3-carboxamide;3-(1-methylpyrazol-4-yl)-N-(2-morpholin-4-ylethyl)imidazo[1,2-a]pyrazin-8-amine;3-(1-methylpyrazol-4-yl)-N-(piperidin-4-ylmethyl)imidazo[1,2-a]pyrazin-8-amine;3-(1-methylpyrazol-4-yl)-N-(pyrrolidin-3-ylmethyl)imidazo[1,2-a]pyrazin-8-amine
SMILESCCNC(=O)Nc1nccn2c(-c3cnn(C)c3)cnc12.CN(C)c1cccc(Nc2nccn3c(-c4cc5ccccc5s4)cnc23)c1.Cn1cc(-c2cnc3c(NC(=O)Nc4ccccc4)nccn23)cn1.Cn1cc(-c2cnc3c(NC(=O)c4cccnc4)nccn23)cn1.Cn1cc(-c2cnc3c(NC4CCCCC4)nccn23)cn1.Cn1cc(-c2cnc3c(NCC4CCNC4)nccn23)cn1.Cn1cc(-c2cnc3c(NCC4CCNCC4)nccn23)cn1.Cn1cc(-c2cnc3c(NCCN4CCOCC4)nccn23)cn1
InChIInChI=1S/C22H19N5S.C17H15N7O.C16H21N7O.C16H13N7O.C16H21N7.C16H20N6.C15H19N7.C13H15N7O/c1-26(2)17-8-5-7-16(13-17)25-21-22-24-14-18(27(22)11-10-23-21)20-12-15-6-3-4-9-19(15)28-20;1-23-11-12(9-20-23)14-10-19-16-15(18-7-8-24(14)16)22-17(25)21-13-5-3-2-4-6-13;1-21-12-13(10-20-21)14-11-19-16-15(18-3-5-23(14)16)17-2-4-22-6-8-24-9-7-22;1-22-10-12(8-20-22)13-9-19-15-14(18-5-6-23(13)15)21-16(24)11-3-2-4-17-7-11;1-22-11-13(9-21-22)14-10-20-16-15(18-6-7-23(14)16)19-8-12-2-4-17-5-3-12;1-21-11-12(9-19-21)14-10-18-16-15(17-7-8-22(14)16)20-13-5-3-2-4-6-13;1-21-10-12(8-20-21)13-9-19-15-14(17-4-5-22(13)15)18-7-11-2-3-16-6-11;1-3-14-13(21)18-11-12-16-7-10(20(12)5-4-15-11)9-6-17-19(2)8-9/h3-14H,1-2H3,(H,23,25);2-11H,1H3,(H2,18,21,22,25);3,5,10-12H,2,4,6-9H2,1H3,(H,17,18);2-10H,1H3,(H,18,21,24);6-7,9-12,17H,2-5,8H2,1H3,(H,18,19);7-11,13H,2-6H2,1H3,(H,17,20);4-5,8-11,16H,2-3,6-7H2,1H3,(H,17,18);4-8H,3H2,1-2H3,(H2,14,15,18,21)
InChIKeyLGOKBYJMAGTMFP-UHFFFAOYSA-N
MW2556.02 g/mol
LogP17.68
Rot. Bonds29

About 1-N-[3-(1-benzothiophen-2-yl)imidazo[1,2-a]pyrazin-8-yl]-3-N,3-N-dimethylbenzene-1,3-diamine;N-cyclohexyl-3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-amine;1-ethyl-3-[3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]urea;1-[3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]-3-phenylurea;N-[3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]pyridine-3-carboxamide;3-(1-methylpyrazol-4-yl)-N-(2-morpholin-4-ylethyl)imidazo[1,2-a]pyrazin-8-amine;3-(1-methylpyrazol-4-yl)-N-(piperidin-4-ylmethyl)imidazo[1,2-a]pyrazin-8-amine;3-(1-methylpyrazol-4-yl)-N-(pyrrolidin-3-ylmethyl)imidazo[1,2-a]pyrazin-8-amine

1-N-[3-(1-benzothiophen-2-yl)imidazo[1,2-a]pyrazin-8-yl]-3-N,3-N-dimethylbenzene-1,3-diamine;N-cyclohexyl-3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-amine;1-ethyl-3-[3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]urea;1-[3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]-3-phenylurea;N-[3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]pyridine-3-carboxamide;3-(1-methylpyrazol-4-yl)-N-(2-morpholin-4-ylethyl)imidazo[1,2-a]pyrazin-8-amine;3-(1-methylpyrazol-4-yl)-N-(piperidin-4-ylmethyl)imidazo[1,2-a]pyrazin-8-amine;3-(1-methylpyrazol-4-yl)-N-(pyrrolidin-3-ylmethyl)imidazo[1,2-a]pyrazin-8-amine (PubChem CID 159344670) has the molecular formula C131H143N53O4S and a molecular weight of 2556.02 g/mol. Its IUPAC name is 1-N-[3-(1-benzothiophen-2-yl)imidazo[1,2-a]pyrazin-8-yl]-3-N,3-N-dimethylbenzene-1,3-diamine;N-cyclohexyl-3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-amine;1-ethyl-3-[3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]urea;1-[3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]-3-phenylurea;N-[3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]pyridine-3-carboxamide;3-(1-methylpyrazol-4-yl)-N-(2-morpholin-4-ylethyl)imidazo[1,2-a]pyrazin-8-amine;3-(1-methylpyrazol-4-yl)-N-(piperidin-4-ylmethyl)imidazo[1,2-a]pyrazin-8-amine;3-(1-methylpyrazol-4-yl)-N-(pyrrolidin-3-ylmethyl)imidazo[1,2-a]pyrazin-8-amine.

Molecular Properties

Compound Name1-N-[3-(1-benzothiophen-2-yl)imidazo[1,2-a]pyrazin-8-yl]-3-N,3-N-dimethylbenzene-1,3-diamine;N-cyclohexyl-3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-amine;1-ethyl-3-[3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]urea;1-[3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]-3-phenylurea;N-[3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]pyridine-3-carboxamide;3-(1-methylpyrazol-4-yl)-N-(2-morpholin-4-ylethyl)imidazo[1,2-a]pyrazin-8-amine;3-(1-methylpyrazol-4-yl)-N-(piperidin-4-ylmethyl)imidazo[1,2-a]pyrazin-8-amine;3-(1-methylpyrazol-4-yl)-N-(pyrrolidin-3-ylmethyl)imidazo[1,2-a]pyrazin-8-amine
PubChem CID159344670
Molecular FormulaC131H143N53O4S
Molecular Weight2556.02 g/mol
Exact Mass2554.23
IUPAC Name1-N-[3-(1-benzothiophen-2-yl)imidazo[1,2-a]pyrazin-8-yl]-3-N,3-N-dimethylbenzene-1,3-diamine;N-cyclohexyl-3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-amine;1-ethyl-3-[3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]urea;1-[3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]-3-phenylurea;N-[3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]pyridine-3-carboxamide;3-(1-methylpyrazol-4-yl)-N-(2-morpholin-4-ylethyl)imidazo[1,2-a]pyrazin-8-amine;3-(1-methylpyrazol-4-yl)-N-(piperidin-4-ylmethyl)imidazo[1,2-a]pyrazin-8-amine;3-(1-methylpyrazol-4-yl)-N-(pyrrolidin-3-ylmethyl)imidazo[1,2-a]pyrazin-8-amine
SMILESCCNC(=O)Nc1nccn2c(-c3cnn(C)c3)cnc12.CN(C)c1cccc(Nc2nccn3c(-c4cc5ccccc5s4)cnc23)c1.Cn1cc(-c2cnc3c(NC(=O)Nc4ccccc4)nccn23)cn1.Cn1cc(-c2cnc3c(NC(=O)c4cccnc4)nccn23)cn1.Cn1cc(-c2cnc3c(NC4CCCCC4)nccn23)cn1.Cn1cc(-c2cnc3c(NCC4CCNC4)nccn23)cn1.Cn1cc(-c2cnc3c(NCC4CCNCC4)nccn23)cn1.Cn1cc(-c2cnc3c(NCCN4CCOCC4)nccn23)cn1
InChIInChI=1S/C22H19N5S.C17H15N7O.C16H21N7O.C16H13N7O.C16H21N7.C16H20N6.C15H19N7.C13H15N7O/c1-26(2)17-8-5-7-16(13-17)25-21-22-24-14-18(27(22)11-10-23-21)20-12-15-6-3-4-9-19(15)28-20;1-23-11-12(9-20-23)14-10-19-16-15(18-7-8-24(14)16)22-17(25)21-13-5-3-2-4-6-13;1-21-12-13(10-20-21)14-11-19-16-15(18-3-5-23(14)16)17-2-4-22-6-8-24-9-7-22;1-22-10-12(8-20-22)13-9-19-15-14(18-5-6-23(13)15)21-16(24)11-3-2-4-17-7-11;1-22-11-13(9-21-22)14-10-20-16-15(18-6-7-23(14)16)19-8-12-2-4-17-5-3-12;1-21-11-12(9-19-21)14-10-18-16-15(17-7-8-22(14)16)20-13-5-3-2-4-6-13;1-21-10-12(8-20-21)13-9-19-15-14(17-4-5-22(13)15)18-7-11-2-3-16-6-11;1-3-14-13(21)18-11-12-16-7-10(20(12)5-4-15-11)9-6-17-19(2)8-9/h3-14H,1-2H3,(H,23,25);2-11H,1H3,(H2,18,21,22,25);3,5,10-12H,2,4,6-9H2,1H3,(H,17,18);2-10H,1H3,(H,18,21,24);6-7,9-12,17H,2-5,8H2,1H3,(H,18,19);7-11,13H,2-6H2,1H3,(H,17,20);4-5,8-11,16H,2-3,6-7H2,1H3,(H,17,18);4-8H,3H2,1-2H3,(H2,14,15,18,21)
InChIKeyLGOKBYJMAGTMFP-UHFFFAOYSA-N
XLogP17.68
TPSA590.43 Ų
H-Bond Donors12
H-Bond Acceptors53
Rotatable Bonds29
Heavy Atoms189
Complexity—

Lipinski Rule of Five

4 violations

RuleValue
MW ≤ 5002556.02
LogP ≤ 517.68
H-Bond Donors ≤ 512
H-Bond Acceptors ≤ 1053

Analyze 1-N-[3-(1-benzothiophen-2-yl)imidazo[1,2-a]pyrazin-8-yl]-3-N,3-N-dimethylbenzene-1,3-diamine;N-cyclohexyl-3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-amine;1-ethyl-3-[3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]urea;1-[3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]-3-phenylurea;N-[3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]pyridine-3-carboxamide;3-(1-methylpyrazol-4-yl)-N-(2-morpholin-4-ylethyl)imidazo[1,2-a]pyrazin-8-amine;3-(1-methylpyrazol-4-yl)-N-(piperidin-4-ylmethyl)imidazo[1,2-a]pyrazin-8-amine;3-(1-methylpyrazol-4-yl)-N-(pyrrolidin-3-ylmethyl)imidazo[1,2-a]pyrazin-8-amine with MolForge

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Related Compounds

8-(dimethylamino)-3-(4,6-dimethyl-2-morpholin-4-ylpyrimidin-5-yl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-3-[1-methyl-3-(trifluoromethyl)pyrazol-5-yl]-8-thiophen-2-yl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-3-(2-morpholin-4-ylpyrimidin-5-yl)-8-thiophen-2-yl-1,3-diazaspiro[4.5]decan-2-one;6-[8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]pyridine-3-carboxamide;N-[5-[8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]pyrimidin-2-yl]acetamide;8-(dimethylamino)-8-phenyl-3-(1H-pyrrolo[2,3-b]pyridin-5-yl)-1,3-diazaspiro[4.5]decan-2-one;bis(8-[methyl(oxolan-3-ylmethyl)amino]-3-[2-(4-methylpiperazin-1-yl)pyrimidin-5-yl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one)
CID 158798655
N-[4-fluoro-3-(4-methylpiperazin-1-yl)-5-(trifluoromethyl)phenyl]-4-methyl-3-[4-(2-methyl-1,3-thiazol-5-yl)triazol-1-yl]benzamide;N-[4-fluoro-3-(4-methylpiperazin-1-yl)-5-(trifluoromethyl)phenyl]-4-methyl-3-[4-(5-morpholin-4-yl-3-pyridinyl)triazol-1-yl]benzamide;4-methyl-N-[3-(4-methylimidazol-1-yl)-5-(trifluoromethyl)phenyl]-3-[4-(1-methylpyrazol-4-yl)triazol-1-yl]benzamide;4-methyl-N-[3-(4-methylpiperazin-1-yl)-5-(trifluoromethyl)phenyl]-3-[4-(2-methyl-1,3-thiazol-5-yl)triazol-1-yl]benzamide;4-methyl-N-[3-(4-methylpiperazin-1-yl)-5-(trifluoromethyl)phenyl]-3-[4-(2-oxo-1,3-dihydroimidazo[4,5-b]pyridin-6-yl)triazol-1-yl]benzamide
CID 159011746
[(2S)-2-[5-[(3S)-3-aminopyrrolidin-1-yl]-6-methylpyrazolo[1,5-a]pyrimidin-2-yl]piperidin-1-yl]-[2-(difluoromethyl)-5-methylpyrazol-3-yl]methanone;[(2S)-2-[5-[(3S)-3-aminopyrrolidin-1-yl]-6-methylpyrazolo[1,5-a]pyrimidin-2-yl]piperidin-1-yl]-(5-ethylthiophen-2-yl)methanone;[(2S)-2-[5-[(3S)-3-aminopyrrolidin-1-yl]-6-methylpyrazolo[1,5-a]pyrimidin-2-yl]piperidin-1-yl]-[2-(2,2,2-trifluoroethyl)pyrazol-3-yl]methanone;(1,6-dimethylpyrazolo[3,4-b]pyridin-4-yl)-[(2S)-2-[6-methyl-5-[(3S)-3-methylpyrrolidin-1-yl]pyrazolo[1,5-a]pyrimidin-2-yl]piperidin-1-yl]methanone;[(2S)-2-[6-methyl-5-[(3S)-3-methylpyrrolidin-1-yl]pyrazolo[1,5-a]pyrimidin-2-yl]piperidin-1-yl]-(4,5,6,7-tetrahydro-1-benzothiophen-2-yl)methanone
CID 162193562
[4-[[(1R)-1-[3-amino-5-(trifluoromethyl)phenyl]ethyl]amino]-2-methylpyrrolo[2,1-f][1,2,4]triazin-6-yl]-morpholin-4-ylmethanone;[7-[[(1R)-1-[3-amino-5-(trifluoromethyl)phenyl]ethyl]amino]-[1,3]thiazolo[5,4-d]pyrimidin-2-yl]-morpholin-4-ylmethanone;N-[(1R)-1-[3-amino-5-(trifluoromethyl)phenyl]ethyl]-2-chloro-6-(cyclohexen-1-yl)-7-methylpyrrolo[2,3-d]pyrimidin-4-amine;N-[(1R)-1-[3-amino-5-(trifluoromethyl)phenyl]ethyl]-6-cyclohexyl-7-methylpyrrolo[2,3-d]pyrimidin-4-amine;6-(cyclohexen-1-yl)-2-methyl-N-[1-[5-[2-(methylaminomethyl)phenyl]thiophen-2-yl]ethyl]pyrrolo[2,1-f][1,2,4]triazin-4-amine
CID 164974987
[4-[[(1R)-1-[3-amino-5-(trifluoromethyl)phenyl]ethyl]amino]-6-methylpyrazolo[1,5-a]pyrazin-2-yl]-morpholin-4-ylmethanone;N-[(1R)-1-[3-amino-5-(trifluoromethyl)phenyl]ethyl]-2-(cyclohexen-1-yl)thieno[3,2-c]pyridin-4-amine;N-[(1R)-1-[3-amino-5-(trifluoromethyl)phenyl]ethyl]-2-(cyclohexen-1-yl)-[1,2,4]triazolo[1,5-a]pyridin-5-amine;N-[(1R)-1-[3-amino-5-(trifluoromethyl)phenyl]ethyl]-2-(cyclohexen-1-yl)-6-(trifluoromethyl)-[1,2,4]triazolo[1,5-a]pyridin-8-amine;[6-[(1R)-1-[3-amino-5-(trifluoromethyl)phenyl]ethyl]imino-1,4,5,7-tetrahydropurin-8-yl]-morpholin-4-ylmethanone
CID 165063065
[4-[[(1R)-1-[3-amino-5-(trifluoromethyl)phenyl]ethyl]amino]pyrrolo[2,1-f][1,2,4]triazin-6-yl]-morpholin-4-ylmethanone;N-[(1R)-1-[3-amino-5-(trifluoromethyl)phenyl]ethyl]-2-(cyclohexen-1-yl)pyrazolo[1,5-a]pyrimidin-7-amine;N-[(1R)-1-[3-amino-5-(trifluoromethyl)phenyl]ethyl]-6-(cyclohexen-1-yl)thieno[3,2-d]pyrimidin-4-amine;N-[(1R)-1-[3-amino-5-(trifluoromethyl)phenyl]ethyl]-2-(cyclohexen-1-yl)-[1,2,4]triazolo[1,5-a]pyrazin-8-amine;[4-[(1R)-1-[3-amino-5-(trifluoromethyl)phenyl]ethyl]imino-2-chloro-3,4a,5,7a-tetrahydropyrrolo[3,2-d]pyrimidin-6-yl]-morpholin-4-ylmethanone
CID 165091779
5-[[6-(cyclohexen-1-yl)-3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]amino]-N-ethyl-3-methylthiophene-2-carboxamide;5-[[6-(cyclohexen-1-yl)-3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]amino]-3-methyl-N-(1-methylsulfonylpiperidin-4-yl)thiophene-2-carboxamide;5-[[6-(cyclohexen-1-yl)-3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]amino]-3-methylthiophene-2-carboxamide;5-[[6-(cyclohexen-1-yl)-3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]amino]-N,N,3-trimethylthiophene-2-carboxamide
CID 123985435
8-amino-N,N-dibenzyl-2-thiophen-2-yl-[1,2,4]triazolo[1,5-a]pyridine-6-carboxamide;8-amino-N-ethyl-N-(2-pyridin-2-ylethyl)-2-thiophen-2-yl-[1,2,4]triazolo[1,5-a]pyridine-6-carboxamide;8-amino-N-(3-hydroxypropyl)-N-methyl-2-phenyl-[1,2,4]triazolo[1,5-a]pyridine-6-carboxamide;8-amino-N-methyl-N-propyl-2-thiophen-2-yl-[1,2,4]triazolo[1,5-a]pyridine-6-carboxamide;(8-amino-2-phenyl-[1,2,4]triazolo[1,5-a]pyridin-6-yl)-(2-methylpyrrolidin-1-yl)methanone;(8-amino-2-phenyl-[1,2,4]triazolo[1,5-a]pyridin-6-yl)-piperidin-1-ylmethanone;(8-amino-2-thiophen-2-yl-[1,2,4]triazolo[1,5-a]pyridin-6-yl)-piperidin-1-ylmethanone
CID 157053664
8-amino-N-butyl-N-methyl-2-(1,3-thiazol-2-yl)-[1,2,4]triazolo[1,5-a]pyridine-6-carboxamide;8-amino-N-methyl-2-(5-methylthiophen-2-yl)-N-(2-phenylethyl)-[1,2,4]triazolo[1,5-a]pyridine-6-carboxamide;8-amino-N-methyl-2-(5-methylthiophen-2-yl)-N-propyl-[1,2,4]triazolo[1,5-a]pyridine-6-carboxamide;[8-amino-2-(5-methylthiophen-2-yl)-[1,2,4]triazolo[1,5-a]pyridin-6-yl]-(3-methylpiperidin-1-yl)methanone;[8-amino-2-(5-methylthiophen-2-yl)-[1,2,4]triazolo[1,5-a]pyridin-6-yl]-thiomorpholin-4-ylmethanone;[8-amino-2-(1,3-thiazol-2-yl)-[1,2,4]triazolo[1,5-a]pyridin-6-yl]-(3-methylpiperidin-1-yl)methanone;[8-amino-2-(1,3-thiazol-2-yl)-[1,2,4]triazolo[1,5-a]pyridin-6-yl]-(2-methylpyrrolidin-1-yl)methanone;[8-amino-2-(1,3-thiazol-2-yl)-[1,2,4]triazolo[1,5-a]pyridin-6-yl]-pyrrolidin-1-ylmethanone
CID 157097527
(4Z)-4-[[7-(cyclopropylamino)-5-[5-(2,5-dimethyl-2,5-dihydropyrrole-1-carbonyl)thiophen-2-yl]pyrazolo[1,5-a]pyrimidin-3-yl]methylidene]-5-methylideneimidazolidin-2-one;5-[7-(cyclopropylamino)-3-[(Z)-(5-methylidene-2-oxoimidazolidin-4-ylidene)methyl]pyrazolo[1,5-a]pyrimidin-5-yl]-N-(2-morpholin-4-ylethyl)thiophene-2-carboxamide;5-[7-(cyclopropylamino)-3-[(Z)-(5-methylidene-2-oxoimidazolidin-4-ylidene)methyl]pyrazolo[1,5-a]pyrimidin-5-yl]-N-(2-pyridin-2-ylethyl)thiophene-2-carboxamide;5-[7-(cyclopropylamino)-3-[(Z)-(5-methylidene-2-oxoimidazolidin-4-ylidene)methyl]pyrazolo[1,5-a]pyrimidin-5-yl]-N-(4-pyrrolidin-1-ylbutyl)thiophene-2-carboxamide;(4Z)-4-[[7-(cyclopropylamino)-5-[5-(1,4-oxazepane-4-carbonyl)thiophen-2-yl]pyrazolo[1,5-a]pyrimidin-3-yl]methylidene]-5-methylideneimidazolidin-2-one
CID 157133015
(4Z)-4-[[7-(cyclopropylamino)-5-[5-(2,5-dimethyl-2,5-dihydropyrrole-1-carbonyl)thiophen-2-yl]pyrazolo[1,5-a]pyrimidin-3-yl]methylidene]-5-methylideneimidazolidin-2-one;5-[7-(cyclopropylamino)-3-[(Z)-(5-methylidene-2-oxoimidazolidin-4-ylidene)methyl]pyrazolo[1,5-a]pyrimidin-5-yl]-N-(2-pyridin-2-ylethyl)thiophene-2-carboxamide;5-[7-(cyclopropylamino)-3-[(Z)-(5-methylidene-2-oxoimidazolidin-4-ylidene)methyl]pyrazolo[1,5-a]pyrimidin-5-yl]-N-(4-pyrrolidin-1-ylbutyl)thiophene-2-carboxamide;(4Z)-4-[[7-(cyclopropylamino)-5-[5-(1,4-oxazepane-4-carbonyl)thiophen-2-yl]pyrazolo[1,5-a]pyrimidin-3-yl]methylidene]-5-methylideneimidazolidin-2-one
CID 157389274
(4E)-4-[[5-[5-[(3R)-3-aminopyrrolidine-1-carbonyl]thiophen-2-yl]-7-(cyclopropylamino)pyrazolo[1,5-a]pyrimidin-3-yl]methylidene]-5-methylidenepyrrolidin-2-one;(4E)-4-[[5-[5-[(3S)-3-aminopyrrolidine-1-carbonyl]thiophen-2-yl]-7-(cyclopropylamino)pyrazolo[1,5-a]pyrimidin-3-yl]methylidene]-5-methylidenepyrrolidin-2-one;5-[7-(cyclopropylamino)-3-[(Z)-(5-methylidene-2-oxoimidazolidin-4-ylidene)methyl]pyrazolo[1,5-a]pyrimidin-5-yl]-N-propan-2-ylthiophene-2-carboxamide;5-[7-(cyclopropylamino)-3-[(E)-(2-methylidene-5-oxopyrrolidin-3-ylidene)methyl]pyrazolo[1,5-a]pyrimidin-5-yl]-N-(2-ethoxyethyl)thiophene-2-carboxamide;5-[7-(cyclopropylamino)-3-[(E)-(2-methylidene-5-oxopyrrolidin-3-ylidene)methyl]pyrazolo[1,5-a]pyrimidin-5-yl]-N-pyrrolidin-3-ylthiophene-2-carboxamide
CID 157627185

Frequently Asked Questions

What is the IUPAC name of 1-N-[3-(1-benzothiophen-2-yl)imidazo[1,2-a]pyrazin-8-yl]-3-N,3-N-dimethylbenzene-1,3-diamine;N-cyclohexyl-3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-amine;1-ethyl-3-[3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]urea;1-[3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]-3-phenylurea;N-[3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]pyridine-3-carboxamide;3-(1-methylpyrazol-4-yl)-N-(2-morpholin-4-ylethyl)imidazo[1,2-a]pyrazin-8-amine;3-(1-methylpyrazol-4-yl)-N-(piperidin-4-ylmethyl)imidazo[1,2-a]pyrazin-8-amine;3-(1-methylpyrazol-4-yl)-N-(pyrrolidin-3-ylmethyl)imidazo[1,2-a]pyrazin-8-amine?
The IUPAC name of 1-N-[3-(1-benzothiophen-2-yl)imidazo[1,2-a]pyrazin-8-yl]-3-N,3-N-dimethylbenzene-1,3-diamine;N-cyclohexyl-3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-amine;1-ethyl-3-[3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]urea;1-[3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]-3-phenylurea;N-[3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]pyridine-3-carboxamide;3-(1-methylpyrazol-4-yl)-N-(2-morpholin-4-ylethyl)imidazo[1,2-a]pyrazin-8-amine;3-(1-methylpyrazol-4-yl)-N-(piperidin-4-ylmethyl)imidazo[1,2-a]pyrazin-8-amine;3-(1-methylpyrazol-4-yl)-N-(pyrrolidin-3-ylmethyl)imidazo[1,2-a]pyrazin-8-amine (CID 159344670) is 1-N-[3-(1-benzothiophen-2-yl)imidazo[1,2-a]pyrazin-8-yl]-3-N,3-N-dimethylbenzene-1,3-diamine;N-cyclohexyl-3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-amine;1-ethyl-3-[3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]urea;1-[3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]-3-phenylurea;N-[3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]pyridine-3-carboxamide;3-(1-methylpyrazol-4-yl)-N-(2-morpholin-4-ylethyl)imidazo[1,2-a]pyrazin-8-amine;3-(1-methylpyrazol-4-yl)-N-(piperidin-4-ylmethyl)imidazo[1,2-a]pyrazin-8-amine;3-(1-methylpyrazol-4-yl)-N-(pyrrolidin-3-ylmethyl)imidazo[1,2-a]pyrazin-8-amine.
What is the SMILES notation for 1-N-[3-(1-benzothiophen-2-yl)imidazo[1,2-a]pyrazin-8-yl]-3-N,3-N-dimethylbenzene-1,3-diamine;N-cyclohexyl-3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-amine;1-ethyl-3-[3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]urea;1-[3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]-3-phenylurea;N-[3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]pyridine-3-carboxamide;3-(1-methylpyrazol-4-yl)-N-(2-morpholin-4-ylethyl)imidazo[1,2-a]pyrazin-8-amine;3-(1-methylpyrazol-4-yl)-N-(piperidin-4-ylmethyl)imidazo[1,2-a]pyrazin-8-amine;3-(1-methylpyrazol-4-yl)-N-(pyrrolidin-3-ylmethyl)imidazo[1,2-a]pyrazin-8-amine?
The canonical SMILES for 1-N-[3-(1-benzothiophen-2-yl)imidazo[1,2-a]pyrazin-8-yl]-3-N,3-N-dimethylbenzene-1,3-diamine;N-cyclohexyl-3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-amine;1-ethyl-3-[3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]urea;1-[3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]-3-phenylurea;N-[3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]pyridine-3-carboxamide;3-(1-methylpyrazol-4-yl)-N-(2-morpholin-4-ylethyl)imidazo[1,2-a]pyrazin-8-amine;3-(1-methylpyrazol-4-yl)-N-(piperidin-4-ylmethyl)imidazo[1,2-a]pyrazin-8-amine;3-(1-methylpyrazol-4-yl)-N-(pyrrolidin-3-ylmethyl)imidazo[1,2-a]pyrazin-8-amine is CCNC(=O)Nc1nccn2c(-c3cnn(C)c3)cnc12.CN(C)c1cccc(Nc2nccn3c(-c4cc5ccccc5s4)cnc23)c1.Cn1cc(-c2cnc3c(NC(=O)Nc4ccccc4)nccn23)cn1.Cn1cc(-c2cnc3c(NC(=O)c4cccnc4)nccn23)cn1.Cn1cc(-c2cnc3c(NC4CCCCC4)nccn23)cn1.Cn1cc(-c2cnc3c(NCC4CCNC4)nccn23)cn1.Cn1cc(-c2cnc3c(NCC4CCNCC4)nccn23)cn1.Cn1cc(-c2cnc3c(NCCN4CCOCC4)nccn23)cn1.
What is the InChIKey of 1-N-[3-(1-benzothiophen-2-yl)imidazo[1,2-a]pyrazin-8-yl]-3-N,3-N-dimethylbenzene-1,3-diamine;N-cyclohexyl-3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-amine;1-ethyl-3-[3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]urea;1-[3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]-3-phenylurea;N-[3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]pyridine-3-carboxamide;3-(1-methylpyrazol-4-yl)-N-(2-morpholin-4-ylethyl)imidazo[1,2-a]pyrazin-8-amine;3-(1-methylpyrazol-4-yl)-N-(piperidin-4-ylmethyl)imidazo[1,2-a]pyrazin-8-amine;3-(1-methylpyrazol-4-yl)-N-(pyrrolidin-3-ylmethyl)imidazo[1,2-a]pyrazin-8-amine?
The InChIKey is LGOKBYJMAGTMFP-UHFFFAOYSA-N. The full InChI is InChI=1S/C22H19N5S.C17H15N7O.C16H21N7O.C16H13N7O.C16H21N7.C16H20N6.C15H19N7.C13H15N7O/c1-26(2)17-8-5-7-16(13-17)25-21-22-24-14-18(27(22)11-10-23-21)20-12-15-6-3-4-9-19(15)28-20;1-23-11-12(9-20-23)14-10-19-16-15(18-7-8-24(14)16)22-17(25)21-13-5-3-2-4-6-13;1-21-12-13(10-20-21)14-11-19-16-15(18-3-5-23(14)16)17-2-4-22-6-8-24-9-7-22;1-22-10-12(8-20-22)13-9-19-15-14(18-5-6-23(13)15)21-16(24)11-3-2-4-17-7-11;1-22-11-13(9-21-22)14-10-20-16-15(18-6-7-23(14)16)19-8-12-2-4-17-5-3-12;1-21-11-12(9-19-21)14-10-18-16-15(17-7-8-22(14)16)20-13-5-3-2-4-6-13;1-21-10-12(8-20-21)13-9-19-15-14(17-4-5-22(13)15)18-7-11-2-3-16-6-11;1-3-14-13(21)18-11-12-16-7-10(20(12)5-4-15-11)9-6-17-19(2)8-9/h3-14H,1-2H3,(H,23,25);2-11H,1H3,(H2,18,21,22,25);3,5,10-12H,2,4,6-9H2,1H3,(H,17,18);2-10H,1H3,(H,18,21,24);6-7,9-12,17H,2-5,8H2,1H3,(H,18,19);7-11,13H,2-6H2,1H3,(H,17,20);4-5,8-11,16H,2-3,6-7H2,1H3,(H,17,18);4-8H,3H2,1-2H3,(H2,14,15,18,21).
What are the key properties of 1-N-[3-(1-benzothiophen-2-yl)imidazo[1,2-a]pyrazin-8-yl]-3-N,3-N-dimethylbenzene-1,3-diamine;N-cyclohexyl-3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-amine;1-ethyl-3-[3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]urea;1-[3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]-3-phenylurea;N-[3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]pyridine-3-carboxamide;3-(1-methylpyrazol-4-yl)-N-(2-morpholin-4-ylethyl)imidazo[1,2-a]pyrazin-8-amine;3-(1-methylpyrazol-4-yl)-N-(piperidin-4-ylmethyl)imidazo[1,2-a]pyrazin-8-amine;3-(1-methylpyrazol-4-yl)-N-(pyrrolidin-3-ylmethyl)imidazo[1,2-a]pyrazin-8-amine?
1-N-[3-(1-benzothiophen-2-yl)imidazo[1,2-a]pyrazin-8-yl]-3-N,3-N-dimethylbenzene-1,3-diamine;N-cyclohexyl-3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-amine;1-ethyl-3-[3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]urea;1-[3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]-3-phenylurea;N-[3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]pyridine-3-carboxamide;3-(1-methylpyrazol-4-yl)-N-(2-morpholin-4-ylethyl)imidazo[1,2-a]pyrazin-8-amine;3-(1-methylpyrazol-4-yl)-N-(piperidin-4-ylmethyl)imidazo[1,2-a]pyrazin-8-amine;3-(1-methylpyrazol-4-yl)-N-(pyrrolidin-3-ylmethyl)imidazo[1,2-a]pyrazin-8-amine has a molecular weight of 2556.02 g/mol, XLogP of 17.68, 29 rotatable bonds, 12 hydrogen bond donors, and 53 hydrogen bond acceptors.
Where does this data come from?
All data for 1-N-[3-(1-benzothiophen-2-yl)imidazo[1,2-a]pyrazin-8-yl]-3-N,3-N-dimethylbenzene-1,3-diamine;N-cyclohexyl-3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-amine;1-ethyl-3-[3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]urea;1-[3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]-3-phenylurea;N-[3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]pyridine-3-carboxamide;3-(1-methylpyrazol-4-yl)-N-(2-morpholin-4-ylethyl)imidazo[1,2-a]pyrazin-8-amine;3-(1-methylpyrazol-4-yl)-N-(piperidin-4-ylmethyl)imidazo[1,2-a]pyrazin-8-amine;3-(1-methylpyrazol-4-yl)-N-(pyrrolidin-3-ylmethyl)imidazo[1,2-a]pyrazin-8-amine is sourced from PubChem (CID 159344670), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).