(1S,5R)-N-[1-(2-chlorophenoxy)-2-methylpropan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1S,5R)-N-[1-[(5-fluoro-3-methyl-2-pyridinyl)oxy]-2-methylpropan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1R,5S)-N-[1-(2-fluorophenoxy)-2-methylpropan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1S,5R)-N-(2-imidazo[1,2-b]pyridazin-3-ylpropan-2-yl)-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1R,5S)-N-[2-methyl-1-(2-methylphenoxy)propan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1R,5S)-N-[2-methyl-1-(3-methylphenoxy)propan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1S,5R)-N-[2-methyl-1-[(3-methyl-2-pyridinyl)oxy]propan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide

C113H154ClF2N19O13 — CID 159371182

IUPAC(1S,5R)-N-[1-(2-chlorophenoxy)-2-methylpropan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1S,5R)-N-[1-[(5-fluoro-3-methyl-2-pyridinyl)oxy]-2-methylpropan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1R,5S)-N-[1-(2-fluorophenoxy)-2-methylpropan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1S,5R)-N-(2-imidazo[1,2-b]pyridazin-3-ylpropan-2-yl)-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1R,5S)-N-[2-methyl-1-(2-methylphenoxy)propan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1R,5S)-N-[2-methyl-1-(3-methylphenoxy)propan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1S,5R)-N-[2-methyl-1-[(3-methyl-2-pyridinyl)oxy]propan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide
SMILESCC(C)(COc1ccccc1Cl)NC(=O)C1[C@H]2CNC[C@@H]12.CC(C)(COc1ccccc1F)NC(=O)C1[C@H]2CNC[C@@H]12.CC(C)(NC(=O)C1[C@H]2CNC[C@@H]12)c1cnc2cccnn12.Cc1cc(F)cnc1OCC(C)(C)NC(=O)C1[C@H]2CNC[C@@H]12.Cc1cccc(OCC(C)(C)NC(=O)C2[C@H]3CNC[C@@H]23)c1.Cc1ccccc1OCC(C)(C)NC(=O)C1[C@H]2CNC[C@@H]12.Cc1cccnc1OCC(C)(C)NC(=O)C1[C@H]2CNC[C@@H]12
InChIInChI=1S/2C17H24N2O2.C16H21ClN2O2.C16H22FN3O2.C16H21FN2O2.C16H23N3O2.C15H19N5O/c1-11-5-4-6-12(7-11)21-10-17(2,3)19-16(20)15-13-8-18-9-14(13)15;1-11-6-4-5-7-14(11)21-10-17(2,3)19-16(20)15-12-8-18-9-13(12)15;1-16(2,9-21-13-6-4-3-5-12(13)17)19-15(20)14-10-7-18-8-11(10)14;1-9-4-10(17)5-19-15(9)22-8-16(2,3)20-14(21)13-11-6-18-7-12(11)13;1-16(2,9-21-13-6-4-3-5-12(13)17)19-15(20)14-10-7-18-8-11(10)14;1-10-5-4-6-18-15(10)21-9-16(2,3)19-14(20)13-11-7-17-8-12(11)13;1-15(2,11-8-17-12-4-3-5-18-20(11)12)19-14(21)13-9-6-16-7-10(9)13/h4-7,13-15,18H,8-10H2,1-3H3,(H,19,20);4-7,12-13,15,18H,8-10H2,1-3H3,(H,19,20);3-6,10-11,14,18H,7-9H2,1-2H3,(H,19,20);4-5,11-13,18H,6-8H2,1-3H3,(H,20,21);3-6,10-11,14,18H,7-9H2,1-2H3,(H,19,20);4-6,11-13,17H,7-9H2,1-3H3,(H,19,20);3-5,8-10,13,16H,6-7H2,1-2H3,(H,19,21)/t13-,14+,15?;12-,13+,15?;10-,11+,14?;11-,12+,13?;10-,11+,14?;11-,12+,13?;9-,10+,13?
InChIKeyLJTMXTCQWBAPNO-IZQOKFDXSA-N
MW2060.04 g/mol
LogP10.05
Rot. Bonds33

About (1S,5R)-N-[1-(2-chlorophenoxy)-2-methylpropan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1S,5R)-N-[1-[(5-fluoro-3-methyl-2-pyridinyl)oxy]-2-methylpropan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1R,5S)-N-[1-(2-fluorophenoxy)-2-methylpropan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1S,5R)-N-(2-imidazo[1,2-b]pyridazin-3-ylpropan-2-yl)-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1R,5S)-N-[2-methyl-1-(2-methylphenoxy)propan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1R,5S)-N-[2-methyl-1-(3-methylphenoxy)propan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1S,5R)-N-[2-methyl-1-[(3-methyl-2-pyridinyl)oxy]propan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide

(1S,5R)-N-[1-(2-chlorophenoxy)-2-methylpropan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1S,5R)-N-[1-[(5-fluoro-3-methyl-2-pyridinyl)oxy]-2-methylpropan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1R,5S)-N-[1-(2-fluorophenoxy)-2-methylpropan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1S,5R)-N-(2-imidazo[1,2-b]pyridazin-3-ylpropan-2-yl)-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1R,5S)-N-[2-methyl-1-(2-methylphenoxy)propan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1R,5S)-N-[2-methyl-1-(3-methylphenoxy)propan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1S,5R)-N-[2-methyl-1-[(3-methyl-2-pyridinyl)oxy]propan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide (PubChem CID 159371182) has the molecular formula C113H154ClF2N19O13 and a molecular weight of 2060.04 g/mol. Its IUPAC name is (1S,5R)-N-[1-(2-chlorophenoxy)-2-methylpropan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1S,5R)-N-[1-[(5-fluoro-3-methyl-2-pyridinyl)oxy]-2-methylpropan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1R,5S)-N-[1-(2-fluorophenoxy)-2-methylpropan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1S,5R)-N-(2-imidazo[1,2-b]pyridazin-3-ylpropan-2-yl)-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1R,5S)-N-[2-methyl-1-(2-methylphenoxy)propan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1R,5S)-N-[2-methyl-1-(3-methylphenoxy)propan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1S,5R)-N-[2-methyl-1-[(3-methyl-2-pyridinyl)oxy]propan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide.

Molecular Properties

Compound Name(1S,5R)-N-[1-(2-chlorophenoxy)-2-methylpropan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1S,5R)-N-[1-[(5-fluoro-3-methyl-2-pyridinyl)oxy]-2-methylpropan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1R,5S)-N-[1-(2-fluorophenoxy)-2-methylpropan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1S,5R)-N-(2-imidazo[1,2-b]pyridazin-3-ylpropan-2-yl)-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1R,5S)-N-[2-methyl-1-(2-methylphenoxy)propan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1R,5S)-N-[2-methyl-1-(3-methylphenoxy)propan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1S,5R)-N-[2-methyl-1-[(3-methyl-2-pyridinyl)oxy]propan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide
PubChem CID159371182
Molecular FormulaC113H154ClF2N19O13
Molecular Weight2060.04 g/mol
Exact Mass2058.16
IUPAC Name(1S,5R)-N-[1-(2-chlorophenoxy)-2-methylpropan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1S,5R)-N-[1-[(5-fluoro-3-methyl-2-pyridinyl)oxy]-2-methylpropan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1R,5S)-N-[1-(2-fluorophenoxy)-2-methylpropan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1S,5R)-N-(2-imidazo[1,2-b]pyridazin-3-ylpropan-2-yl)-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1R,5S)-N-[2-methyl-1-(2-methylphenoxy)propan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1R,5S)-N-[2-methyl-1-(3-methylphenoxy)propan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1S,5R)-N-[2-methyl-1-[(3-methyl-2-pyridinyl)oxy]propan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide
SMILESCC(C)(COc1ccccc1Cl)NC(=O)C1[C@H]2CNC[C@@H]12.CC(C)(COc1ccccc1F)NC(=O)C1[C@H]2CNC[C@@H]12.CC(C)(NC(=O)C1[C@H]2CNC[C@@H]12)c1cnc2cccnn12.Cc1cc(F)cnc1OCC(C)(C)NC(=O)C1[C@H]2CNC[C@@H]12.Cc1cccc(OCC(C)(C)NC(=O)C2[C@H]3CNC[C@@H]23)c1.Cc1ccccc1OCC(C)(C)NC(=O)C1[C@H]2CNC[C@@H]12.Cc1cccnc1OCC(C)(C)NC(=O)C1[C@H]2CNC[C@@H]12
InChIInChI=1S/2C17H24N2O2.C16H21ClN2O2.C16H22FN3O2.C16H21FN2O2.C16H23N3O2.C15H19N5O/c1-11-5-4-6-12(7-11)21-10-17(2,3)19-16(20)15-13-8-18-9-14(13)15;1-11-6-4-5-7-14(11)21-10-17(2,3)19-16(20)15-12-8-18-9-13(12)15;1-16(2,9-21-13-6-4-3-5-12(13)17)19-15(20)14-10-7-18-8-11(10)14;1-9-4-10(17)5-19-15(9)22-8-16(2,3)20-14(21)13-11-6-18-7-12(11)13;1-16(2,9-21-13-6-4-3-5-12(13)17)19-15(20)14-10-7-18-8-11(10)14;1-10-5-4-6-18-15(10)21-9-16(2,3)19-14(20)13-11-7-17-8-12(11)13;1-15(2,11-8-17-12-4-3-5-18-20(11)12)19-14(21)13-9-6-16-7-10(9)13/h4-7,13-15,18H,8-10H2,1-3H3,(H,19,20);4-7,12-13,15,18H,8-10H2,1-3H3,(H,19,20);3-6,10-11,14,18H,7-9H2,1-2H3,(H,19,20);4-5,11-13,18H,6-8H2,1-3H3,(H,20,21);3-6,10-11,14,18H,7-9H2,1-2H3,(H,19,20);4-6,11-13,17H,7-9H2,1-3H3,(H,19,20);3-5,8-10,13,16H,6-7H2,1-2H3,(H,19,21)/t13-,14+,15?;12-,13+,15?;10-,11+,14?;11-,12+,13?;10-,11+,14?;11-,12+,13?;9-,10+,13?
InChIKeyLJTMXTCQWBAPNO-IZQOKFDXSA-N
XLogP10.05
TPSA399.26 Ų
H-Bond Donors14
H-Bond Acceptors25
Rotatable Bonds33
Heavy Atoms148
Complexity—

Lipinski Rule of Five

4 violations

RuleValue
MW ≤ 5002060.04
LogP ≤ 510.05
H-Bond Donors ≤ 514
H-Bond Acceptors ≤ 1025

Analyze (1S,5R)-N-[1-(2-chlorophenoxy)-2-methylpropan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1S,5R)-N-[1-[(5-fluoro-3-methyl-2-pyridinyl)oxy]-2-methylpropan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1R,5S)-N-[1-(2-fluorophenoxy)-2-methylpropan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1S,5R)-N-(2-imidazo[1,2-b]pyridazin-3-ylpropan-2-yl)-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1R,5S)-N-[2-methyl-1-(2-methylphenoxy)propan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1R,5S)-N-[2-methyl-1-(3-methylphenoxy)propan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1S,5R)-N-[2-methyl-1-[(3-methyl-2-pyridinyl)oxy]propan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide with MolForge

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Related Compounds

N-[2-[[5-[3-[6-amino-5-(trifluoromethyl)-3-pyridinyl]imidazo[1,2-b]pyridazin-6-yl]-2-pyridinyl]oxy]ethyl]cyclopropanecarboxamide;N-[3-[[5-[3-[6-amino-5-(trifluoromethyl)-3-pyridinyl]imidazo[1,2-b]pyridazin-6-yl]-2-pyridinyl]oxy]propyl]-2-methylpropanamide;N-[3-[[5-[3-(2-methyl-4-pyridinyl)imidazo[1,2-b]pyridazin-6-yl]-2-pyridinyl]oxy]propyl]cyclopropanecarboxamide;N-[3-[[5-[3-[2-(trifluoromethyl)-4-pyridinyl]imidazo[1,2-b]pyridazin-6-yl]-2-pyridinyl]oxy]propyl]cyclopropanecarboxamide
CID 157597360
(1S,5R)-N-[1-[(4-cyclopropyl-3-pyridinyl)oxy]-2-methylpropan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1R,5S)-N-(1-imidazo[1,2-a]pyridin-8-yloxy-2-methylpropan-2-yl)-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1S,5R)-N-[2-methyl-1-(2-methylpyrazol-3-yl)oxypropan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1S,5R)-N-[1-(2-methylphenoxy)propan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1S,5R)-N-[2-methyl-1-[4-(trifluoromethyl)pyridazin-3-yl]oxypropan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide
CID 158274742
(1S,5R)-N-[1-(2-ethylphenoxy)-2-methylpropan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1S,5R)-N-[2-methyl-1-(3-methylpyrazin-2-yl)oxypropan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1S,5R)-N-[2-methyl-1-[(4-methyl-3-pyridinyl)oxy]propan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1R,5S)-N-[2-(1-methylpyrazolo[5,4-b]pyridin-3-yl)propan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1R,5S)-N-[2-(2-methylquinolin-4-yl)propan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1S,5R)-N-[2-[1-(trifluoromethyl)imidazo[1,5-a]pyridin-3-yl]propan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide
CID 158599699
CID 159459122
CID 159459122
(1R,5S)-N-[2-(3,4-dihydro-2H-chromen-2-yl)propan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1S,5R)-N-[2-methyl-4-(3-methyl-2-pyridinyl)butan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1R,5S)-N-[2-(1-methylpyrazolo[5,4-b]pyridin-3-yl)propan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1S,5R)-N-[2-methyl-4-[3-(trifluoromethyl)-2-pyridinyl]butan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1R,5S)-N-[2-[1-(trifluoromethyl)imidazo[1,5-a]pyridin-3-yl]propan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide
CID 160302057
2-(4-chloro-3-fluorophenoxy)-N-[3-[(3-methylpyrazolo[1,5-a]pyrimidin-5-yl)amino]-1-bicyclo[1.1.1]pentanyl]acetamide;2-(4-chloro-3-methylphenoxy)-N-[3-(pyrazolo[1,5-a]pyrimidin-5-ylamino)-1-bicyclo[1.1.1]pentanyl]acetamide;2-(4-fluorophenoxy)-N-[3-[(2-methylpyrazolo[1,5-a]pyrazin-4-yl)amino]-1-bicyclo[1.1.1]pentanyl]acetamide;2-[3-fluoro-4-(trifluoromethoxy)phenoxy]-N-[3-[(2-methylpyrazolo[1,5-a]pyrazin-4-yl)amino]-1-bicyclo[1.1.1]pentanyl]acetamide;N-[3-[(2-methylpyrazolo[1,5-a]pyrazin-4-yl)amino]-1-bicyclo[1.1.1]pentanyl]-2-(3,4,5-trifluorophenoxy)acetamide
CID 165029160
N-[5-chloro-4-(trifluoromethyl)-2-pyridinyl]-2-(4-imidazo[1,2-a]pyrazin-3-ylanilino)acetamide;1-N'-[5-chloro-4-(trifluoromethyl)-2-pyridinyl]-1-N-(4-imidazo[1,2-a]pyrazin-3-ylphenyl)cyclopropane-1,1-dicarboxamide;2-(3-fluoro-4-imidazo[1,2-a]pyrazin-3-ylanilino)-N-[1-methyl-5-(trifluoromethyl)pyrazol-3-yl]acetamide;1-N-(3-fluoro-4-imidazo[1,2-a]pyrazin-3-ylphenyl)-1-N'-[1-methyl-5-(trifluoromethyl)pyrazol-3-yl]cyclopropane-1,1-dicarboxamide;2-(4-imidazo[1,2-a]pyrazin-3-ylanilino)-N-[1-methyl-5-(trifluoromethyl)pyrazol-3-yl]acetamide;1-N-(4-imidazo[1,2-a]pyrazin-3-ylphenyl)-1-N'-[1-methyl-5-(trifluoromethyl)pyrazol-3-yl]cyclopropane-1,1-dicarboxamide;N-[1-methyl-5-(trifluoromethyl)pyrazol-3-yl]-2-(4-pyrazolo[1,5-a]pyrimidin-3-ylphenoxy)acetamide
CID 167558731
N-[5-chloro-4-(trifluoromethyl)-2-pyridinyl]-2-(4-imidazo[1,2-a]pyrazin-3-ylanilino)acetamide;1-N'-[5-chloro-4-(trifluoromethyl)-2-pyridinyl]-1-N-(4-imidazo[1,2-a]pyrazin-3-ylphenyl)cyclopropane-1,1-dicarboxamide;1-N'-[5-(1,1-difluoroethyl)-1-methylpyrazol-3-yl]-1-N-(4-imidazo[1,2-a]pyrazin-3-ylphenyl)cyclopropane-1,1-dicarboxamide;2-(3-fluoro-4-imidazo[1,2-a]pyrazin-3-ylanilino)-N-[1-methyl-5-(trifluoromethyl)pyrazol-3-yl]acetamide;1-N-(3-fluoro-4-imidazo[1,2-a]pyrazin-3-ylphenyl)-1-N'-[1-methyl-5-(trifluoromethyl)pyrazol-3-yl]cyclopropane-1,1-dicarboxamide;2-(4-imidazo[1,2-a]pyrazin-3-ylanilino)-N-[1-methyl-5-(trifluoromethyl)pyrazol-3-yl]acetamide;N-[1-methyl-5-(trifluoromethyl)pyrazol-3-yl]-2-(4-pyrazolo[1,5-a]pyrimidin-3-ylphenoxy)acetamide
CID 167667485
N-[1-[(1R,5S)-3-azabicyclo[3.1.0]hexan-6-yl]ethenyl]-2-methyl-1-[(3-methyl-2-pyridinyl)oxy]propan-2-amine;(1R,5S)-N-[1-(2-chlorophenoxy)-2-methylpropan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1R,5S)-N-[1-(2-ethylphenoxy)-2-methylpropan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1R,5S)-N-[1-[(5-fluoro-3-methyl-2-pyridinyl)oxy]-2-methylpropan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1R,5S)-N-[1-(2-fluorophenoxy)-2-methylpropan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1R,5S)-N-(imidazo[1,2-b]pyridazin-3-ylmethyl)-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1S,5R)-N-[2-methyl-1-(2-methylphenoxy)propan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1R,5S)-N-[2-methyl-1-(3-methylphenoxy)propan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide
CID 157050463
(4Z)-4-[[5-[[(1S)-1-(5-chloro-2-fluorophenyl)ethyl]amino]-7-(cyclopropylamino)pyrazolo[1,5-a]pyrimidin-3-yl]methylidene]-5-methylideneimidazolidin-2-one;(4E)-4-[[5-(3-chloro-2-methoxyanilino)-7-(cyclopropylamino)pyrazolo[1,5-a]pyrimidin-3-yl]methylidene]-5-methylidenepyrrolidin-2-one;(4E)-4-[[7-(cyclopropylamino)-5-(3-fluoro-2-methoxyanilino)pyrazolo[1,5-a]pyrimidin-3-yl]methylidene]-5-methylidenepyrrolidin-2-one;2-[4-[7-(cyclopropylamino)-3-[(E)-(2-methylidene-5-oxopyrrolidin-3-ylidene)methyl]pyrazolo[1,5-a]pyrimidin-5-yl]piperazine-1-carbonyl]cyclopropane-1-carbonitrile;(4E)-4-[[7-(cyclopropylamino)-5-(4-piperidin-1-ylanilino)pyrazolo[1,5-a]pyrimidin-3-yl]methylidene]-5-methylidenepyrrolidin-2-one
CID 157325631
N-[1-[(1S,5R)-3-azabicyclo[3.1.0]hexan-6-yl]ethenyl]-2-methyl-1-[(2-methyl-3-pyridinyl)oxy]propan-2-amine;(1S,5R)-N-[1-(2-chlorophenoxy)-2-methylpropan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1S,5R)-N-[1-(2-ethylphenoxy)-2-methylpropan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1S,5R)-N-[1-(2-fluorophenoxy)-2-methylpropan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1S,5R)-N-[2-(1-methylimidazo[1,5-a]pyridin-3-yl)propan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1R,5S)-N-[2-methyl-1-(2-methylphenoxy)propan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1R,5S)-N-[2-methyl-1-(3-methylphenoxy)propan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide
CID 157546760
(16R)-10-fluoro-16-methyl-18-methylidene-2,12,17,21,25,26-hexazahexacyclo[17.5.2.02,7.05,7.08,13.022,26]hexacosa-1(25),8(13),9,11,19,21,23-heptaene;(15S)-10-fluoro-15-methyl-18-methylidene-14-oxa-2,12,17,21,25,26-hexazahexacyclo[17.5.2.02,7.05,7.08,13.022,26]hexacosa-1(25),8(13),9,11,19,21,23-heptaene;(15S)-10-fluoro-15-methyl-18-methylidene-14-oxa-2,17,21,25,26-pentazahexacyclo[17.5.2.02,7.05,7.08,13.022,26]hexacosa-1(25),8(13),9,11,19,21,23-heptaene;(5S,7R,16S)-10-fluoro-16-methyl-18-methylidene-2,17,21,22,25-pentazahexacyclo[17.5.2.02,7.05,7.08,13.022,26]hexacosa-1(25),8(13),9,11,19(26),20,23-heptaene;(16R)-10-fluoro-16-methyl-18-methylidene-2,17,21,25,26-pentazahexacyclo[17.5.2.02,7.05,7.08,13.022,26]hexacosa-1(25),8(13),9,11,19,21,23-heptaene
CID 157649303

Frequently Asked Questions

What is the IUPAC name of (1S,5R)-N-[1-(2-chlorophenoxy)-2-methylpropan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1S,5R)-N-[1-[(5-fluoro-3-methyl-2-pyridinyl)oxy]-2-methylpropan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1R,5S)-N-[1-(2-fluorophenoxy)-2-methylpropan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1S,5R)-N-(2-imidazo[1,2-b]pyridazin-3-ylpropan-2-yl)-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1R,5S)-N-[2-methyl-1-(2-methylphenoxy)propan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1R,5S)-N-[2-methyl-1-(3-methylphenoxy)propan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1S,5R)-N-[2-methyl-1-[(3-methyl-2-pyridinyl)oxy]propan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide?
The IUPAC name of (1S,5R)-N-[1-(2-chlorophenoxy)-2-methylpropan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1S,5R)-N-[1-[(5-fluoro-3-methyl-2-pyridinyl)oxy]-2-methylpropan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1R,5S)-N-[1-(2-fluorophenoxy)-2-methylpropan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1S,5R)-N-(2-imidazo[1,2-b]pyridazin-3-ylpropan-2-yl)-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1R,5S)-N-[2-methyl-1-(2-methylphenoxy)propan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1R,5S)-N-[2-methyl-1-(3-methylphenoxy)propan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1S,5R)-N-[2-methyl-1-[(3-methyl-2-pyridinyl)oxy]propan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide (CID 159371182) is (1S,5R)-N-[1-(2-chlorophenoxy)-2-methylpropan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1S,5R)-N-[1-[(5-fluoro-3-methyl-2-pyridinyl)oxy]-2-methylpropan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1R,5S)-N-[1-(2-fluorophenoxy)-2-methylpropan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1S,5R)-N-(2-imidazo[1,2-b]pyridazin-3-ylpropan-2-yl)-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1R,5S)-N-[2-methyl-1-(2-methylphenoxy)propan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1R,5S)-N-[2-methyl-1-(3-methylphenoxy)propan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1S,5R)-N-[2-methyl-1-[(3-methyl-2-pyridinyl)oxy]propan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide.
What is the SMILES notation for (1S,5R)-N-[1-(2-chlorophenoxy)-2-methylpropan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1S,5R)-N-[1-[(5-fluoro-3-methyl-2-pyridinyl)oxy]-2-methylpropan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1R,5S)-N-[1-(2-fluorophenoxy)-2-methylpropan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1S,5R)-N-(2-imidazo[1,2-b]pyridazin-3-ylpropan-2-yl)-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1R,5S)-N-[2-methyl-1-(2-methylphenoxy)propan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1R,5S)-N-[2-methyl-1-(3-methylphenoxy)propan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1S,5R)-N-[2-methyl-1-[(3-methyl-2-pyridinyl)oxy]propan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide?
The canonical SMILES for (1S,5R)-N-[1-(2-chlorophenoxy)-2-methylpropan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1S,5R)-N-[1-[(5-fluoro-3-methyl-2-pyridinyl)oxy]-2-methylpropan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1R,5S)-N-[1-(2-fluorophenoxy)-2-methylpropan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1S,5R)-N-(2-imidazo[1,2-b]pyridazin-3-ylpropan-2-yl)-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1R,5S)-N-[2-methyl-1-(2-methylphenoxy)propan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1R,5S)-N-[2-methyl-1-(3-methylphenoxy)propan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1S,5R)-N-[2-methyl-1-[(3-methyl-2-pyridinyl)oxy]propan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide is CC(C)(COc1ccccc1Cl)NC(=O)C1[C@H]2CNC[C@@H]12.CC(C)(COc1ccccc1F)NC(=O)C1[C@H]2CNC[C@@H]12.CC(C)(NC(=O)C1[C@H]2CNC[C@@H]12)c1cnc2cccnn12.Cc1cc(F)cnc1OCC(C)(C)NC(=O)C1[C@H]2CNC[C@@H]12.Cc1cccc(OCC(C)(C)NC(=O)C2[C@H]3CNC[C@@H]23)c1.Cc1ccccc1OCC(C)(C)NC(=O)C1[C@H]2CNC[C@@H]12.Cc1cccnc1OCC(C)(C)NC(=O)C1[C@H]2CNC[C@@H]12.
What is the InChIKey of (1S,5R)-N-[1-(2-chlorophenoxy)-2-methylpropan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1S,5R)-N-[1-[(5-fluoro-3-methyl-2-pyridinyl)oxy]-2-methylpropan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1R,5S)-N-[1-(2-fluorophenoxy)-2-methylpropan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1S,5R)-N-(2-imidazo[1,2-b]pyridazin-3-ylpropan-2-yl)-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1R,5S)-N-[2-methyl-1-(2-methylphenoxy)propan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1R,5S)-N-[2-methyl-1-(3-methylphenoxy)propan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1S,5R)-N-[2-methyl-1-[(3-methyl-2-pyridinyl)oxy]propan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide?
The InChIKey is LJTMXTCQWBAPNO-IZQOKFDXSA-N. The full InChI is InChI=1S/2C17H24N2O2.C16H21ClN2O2.C16H22FN3O2.C16H21FN2O2.C16H23N3O2.C15H19N5O/c1-11-5-4-6-12(7-11)21-10-17(2,3)19-16(20)15-13-8-18-9-14(13)15;1-11-6-4-5-7-14(11)21-10-17(2,3)19-16(20)15-12-8-18-9-13(12)15;1-16(2,9-21-13-6-4-3-5-12(13)17)19-15(20)14-10-7-18-8-11(10)14;1-9-4-10(17)5-19-15(9)22-8-16(2,3)20-14(21)13-11-6-18-7-12(11)13;1-16(2,9-21-13-6-4-3-5-12(13)17)19-15(20)14-10-7-18-8-11(10)14;1-10-5-4-6-18-15(10)21-9-16(2,3)19-14(20)13-11-7-17-8-12(11)13;1-15(2,11-8-17-12-4-3-5-18-20(11)12)19-14(21)13-9-6-16-7-10(9)13/h4-7,13-15,18H,8-10H2,1-3H3,(H,19,20);4-7,12-13,15,18H,8-10H2,1-3H3,(H,19,20);3-6,10-11,14,18H,7-9H2,1-2H3,(H,19,20);4-5,11-13,18H,6-8H2,1-3H3,(H,20,21);3-6,10-11,14,18H,7-9H2,1-2H3,(H,19,20);4-6,11-13,17H,7-9H2,1-3H3,(H,19,20);3-5,8-10,13,16H,6-7H2,1-2H3,(H,19,21)/t13-,14+,15?;12-,13+,15?;10-,11+,14?;11-,12+,13?;10-,11+,14?;11-,12+,13?;9-,10+,13?.
What are the key properties of (1S,5R)-N-[1-(2-chlorophenoxy)-2-methylpropan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1S,5R)-N-[1-[(5-fluoro-3-methyl-2-pyridinyl)oxy]-2-methylpropan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1R,5S)-N-[1-(2-fluorophenoxy)-2-methylpropan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1S,5R)-N-(2-imidazo[1,2-b]pyridazin-3-ylpropan-2-yl)-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1R,5S)-N-[2-methyl-1-(2-methylphenoxy)propan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1R,5S)-N-[2-methyl-1-(3-methylphenoxy)propan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1S,5R)-N-[2-methyl-1-[(3-methyl-2-pyridinyl)oxy]propan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide?
(1S,5R)-N-[1-(2-chlorophenoxy)-2-methylpropan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1S,5R)-N-[1-[(5-fluoro-3-methyl-2-pyridinyl)oxy]-2-methylpropan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1R,5S)-N-[1-(2-fluorophenoxy)-2-methylpropan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1S,5R)-N-(2-imidazo[1,2-b]pyridazin-3-ylpropan-2-yl)-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1R,5S)-N-[2-methyl-1-(2-methylphenoxy)propan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1R,5S)-N-[2-methyl-1-(3-methylphenoxy)propan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1S,5R)-N-[2-methyl-1-[(3-methyl-2-pyridinyl)oxy]propan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide has a molecular weight of 2060.04 g/mol, XLogP of 10.05, 33 rotatable bonds, 14 hydrogen bond donors, and 25 hydrogen bond acceptors.
Where does this data come from?
All data for (1S,5R)-N-[1-(2-chlorophenoxy)-2-methylpropan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1S,5R)-N-[1-[(5-fluoro-3-methyl-2-pyridinyl)oxy]-2-methylpropan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1R,5S)-N-[1-(2-fluorophenoxy)-2-methylpropan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1S,5R)-N-(2-imidazo[1,2-b]pyridazin-3-ylpropan-2-yl)-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1R,5S)-N-[2-methyl-1-(2-methylphenoxy)propan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1R,5S)-N-[2-methyl-1-(3-methylphenoxy)propan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1S,5R)-N-[2-methyl-1-[(3-methyl-2-pyridinyl)oxy]propan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide is sourced from PubChem (CID 159371182), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).