5-(1H-benzimidazol-2-yl)-N-(4-piperazin-1-yl-3-pyridinyl)-1,3-oxazole-2-carboxamide;5-(1-benzofuran-3-yl)-N-(4-piperazin-1-yl-3-pyridinyl)-1,3-oxazole-2-carboxamide;bis(5-(1H-indazol-3-yl)-N-(4-piperazin-1-yl-3-pyridinyl)-1,3-oxazole-2-carboxamide);5-(1H-indol-3-yl)-N-(4-piperazin-1-yl-3-pyridinyl)-1,3-oxazole-2-carboxamide;5-(1H-indol-5-yl)-N-(4-piperazin-1-yl-3-pyridinyl)-1,3-oxazole-2-carboxamide

C123H116N38O13 — CID 159382757

About 5-(1H-benzimidazol-2-yl)-N-(4-piperazin-1-yl-3-pyridinyl)-1,3-oxazole-2-carboxamide;5-(1-benzofuran-3-yl)-N-(4-piperazin-1-yl-3-pyridinyl)-1,3-oxazole-2-carboxamide;bis(5-(1H-indazol-3-yl)-N-(4-piperazin-1-yl-3-pyridinyl)-1,3-oxazole-2-carboxamide);5-(1H-indol-3-yl)-N-(4-piperazin-1-yl-3-pyridinyl)-1,3-oxazole-2-carboxamide;5-(1H-indol-5-yl)-N-(4-piperazin-1-yl-3-pyridinyl)-1,3-oxazole-2-carboxamide

5-(1H-benzimidazol-2-yl)-N-(4-piperazin-1-yl-3-pyridinyl)-1,3-oxazole-2-carboxamide;5-(1-benzofuran-3-yl)-N-(4-piperazin-1-yl-3-pyridinyl)-1,3-oxazole-2-carboxamide;bis(5-(1H-indazol-3-yl)-N-(4-piperazin-1-yl-3-pyridinyl)-1,3-oxazole-2-carboxamide);5-(1H-indol-3-yl)-N-(4-piperazin-1-yl-3-pyridinyl)-1,3-oxazole-2-carboxamide;5-(1H-indol-5-yl)-N-(4-piperazin-1-yl-3-pyridinyl)-1,3-oxazole-2-carboxamide (PubChem CID 159382757) has the molecular formula C123H116N38O13 and a molecular weight of 2334.53 g/mol. Its IUPAC name is 5-(1H-benzimidazol-2-yl)-N-(4-piperazin-1-yl-3-pyridinyl)-1,3-oxazole-2-carboxamide;5-(1-benzofuran-3-yl)-N-(4-piperazin-1-yl-3-pyridinyl)-1,3-oxazole-2-carboxamide;bis(5-(1H-indazol-3-yl)-N-(4-piperazin-1-yl-3-pyridinyl)-1,3-oxazole-2-carboxamide);5-(1H-indol-3-yl)-N-(4-piperazin-1-yl-3-pyridinyl)-1,3-oxazole-2-carboxamide;5-(1H-indol-5-yl)-N-(4-piperazin-1-yl-3-pyridinyl)-1,3-oxazole-2-carboxamide.

Molecular Properties

• Compound Name: 5-(1H-benzimidazol-2-yl)-N-(4-piperazin-1-yl-3-pyridinyl)-1,3-oxazole-2-carboxamide;5-(1-benzofuran-3-yl)-N-(4-piperazin-1-yl-3-pyridinyl)-1,3-oxazole-2-carboxamide;bis(5-(1H-indazol-3-yl)-N-(4-piperazin-1-yl-3-pyridinyl)-1,3-oxazole-2-carboxamide);5-(1H-indol-3-yl)-N-(4-piperazin-1-yl-3-pyridinyl)-1,3-oxazole-2-carboxamide;5-(1H-indol-5-yl)-N-(4-piperazin-1-yl-3-pyridinyl)-1,3-oxazole-2-carboxamide
• PubChem CID: 159382757
• Molecular Formula: C123H116N38O13
• Molecular Weight: 2334.53 g/mol
• Exact Mass: 2332.96
• IUPAC Name: 5-(1H-benzimidazol-2-yl)-N-(4-piperazin-1-yl-3-pyridinyl)-1,3-oxazole-2-carboxamide;5-(1-benzofuran-3-yl)-N-(4-piperazin-1-yl-3-pyridinyl)-1,3-oxazole-2-carboxamide;bis(5-(1H-indazol-3-yl)-N-(4-piperazin-1-yl-3-pyridinyl)-1,3-oxazole-2-carboxamide);5-(1H-indol-3-yl)-N-(4-piperazin-1-yl-3-pyridinyl)-1,3-oxazole-2-carboxamide;5-(1H-indol-5-yl)-N-(4-piperazin-1-yl-3-pyridinyl)-1,3-oxazole-2-carboxamide
• SMILES: O=C(Nc1cnccc1N1CCNCC1)c1ncc(-c2c[nH]c3ccccc23)o1.O=C(Nc1cnccc1N1CCNCC1)c1ncc(-c2ccc3[nH]ccc3c2)o1.O=C(Nc1cnccc1N1CCNCC1)c1ncc(-c2coc3ccccc23)o1.O=C(Nc1cnccc1N1CCNCC1)c1ncc(-c2n[nH]c3ccccc23)o1.O=C(Nc1cnccc1N1CCNCC1)c1ncc(-c2n[nH]c3ccccc23)o1.O=C(Nc1cnccc1N1CCNCC1)c1ncc(-c2nc3ccccc3[nH]2)o1
• InChI: InChI=1S/2C21H20N6O2.C21H19N5O3.3C20H19N7O2/c28-20(26-17-12-23-5-4-18(17)27-9-7-22-8-10-27)21-25-13-19(29-21)15-1-2-16-14(11-15)3-6-24-16;28-20(26-17-12-23-6-5-18(17)27-9-7-22-8-10-27)21-25-13-19(29-21)15-11-24-16-4-2-1-3-14(15)16;27-20(25-16-11-23-6-5-17(16)26-9-7-22-8-10-26)21-24-12-19(29-21)15-13-28-18-4-2-1-3-14(15)18;28-19(26-15-11-22-6-5-16(15)27-9-7-21-8-10-27)20-23-12-17(29-20)18-24-13-3-1-2-4-14(13)25-18;2*28-19(24-15-11-22-6-5-16(15)27-9-7-21-8-10-27)20-23-12-17(29-20)18-13-3-1-2-4-14(13)25-26-18/h2*1-6,11-13,22,24H,7-10H2,(H,26,28);1-6,11-13,22H,7-10H2,(H,25,27);1-6,11-12,21H,7-10H2,(H,24,25)(H,26,28);2*1-6,11-12,21H,7-10H2,(H,24,28)(H,25,26)
• InChIKey: LLCUOIZECDQSNO-UHFFFAOYSA-N
• XLogP: 15.73
• TPSA: 630.50 Ų
• H-Bond Donors: 17
• H-Bond Acceptors: 40
• Rotatable Bonds: 24
• Heavy Atoms: 174
• Complexity: —

Lipinski Rule of Five

4 violations

Rule	Value
MW ≤ 500	2334.53
LogP ≤ 5	15.73
H-Bond Donors ≤ 5	17
H-Bond Acceptors ≤ 10	40

Frequently Asked Questions

What is the IUPAC name of 5-(1H-benzimidazol-2-yl)-N-(4-piperazin-1-yl-3-pyridinyl)-1,3-oxazole-2-carboxamide;5-(1-benzofuran-3-yl)-N-(4-piperazin-1-yl-3-pyridinyl)-1,3-oxazole-2-carboxamide;bis(5-(1H-indazol-3-yl)-N-(4-piperazin-1-yl-3-pyridinyl)-1,3-oxazole-2-carboxamide);5-(1H-indol-3-yl)-N-(4-piperazin-1-yl-3-pyridinyl)-1,3-oxazole-2-carboxamide;5-(1H-indol-5-yl)-N-(4-piperazin-1-yl-3-pyridinyl)-1,3-oxazole-2-carboxamide?

The IUPAC name of 5-(1H-benzimidazol-2-yl)-N-(4-piperazin-1-yl-3-pyridinyl)-1,3-oxazole-2-carboxamide;5-(1-benzofuran-3-yl)-N-(4-piperazin-1-yl-3-pyridinyl)-1,3-oxazole-2-carboxamide;bis(5-(1H-indazol-3-yl)-N-(4-piperazin-1-yl-3-pyridinyl)-1,3-oxazole-2-carboxamide);5-(1H-indol-3-yl)-N-(4-piperazin-1-yl-3-pyridinyl)-1,3-oxazole-2-carboxamide;5-(1H-indol-5-yl)-N-(4-piperazin-1-yl-3-pyridinyl)-1,3-oxazole-2-carboxamide (CID 159382757) is 5-(1H-benzimidazol-2-yl)-N-(4-piperazin-1-yl-3-pyridinyl)-1,3-oxazole-2-carboxamide;5-(1-benzofuran-3-yl)-N-(4-piperazin-1-yl-3-pyridinyl)-1,3-oxazole-2-carboxamide;bis(5-(1H-indazol-3-yl)-N-(4-piperazin-1-yl-3-pyridinyl)-1,3-oxazole-2-carboxamide);5-(1H-indol-3-yl)-N-(4-piperazin-1-yl-3-pyridinyl)-1,3-oxazole-2-carboxamide;5-(1H-indol-5-yl)-N-(4-piperazin-1-yl-3-pyridinyl)-1,3-oxazole-2-carboxamide.

What is the SMILES notation for 5-(1H-benzimidazol-2-yl)-N-(4-piperazin-1-yl-3-pyridinyl)-1,3-oxazole-2-carboxamide;5-(1-benzofuran-3-yl)-N-(4-piperazin-1-yl-3-pyridinyl)-1,3-oxazole-2-carboxamide;bis(5-(1H-indazol-3-yl)-N-(4-piperazin-1-yl-3-pyridinyl)-1,3-oxazole-2-carboxamide);5-(1H-indol-3-yl)-N-(4-piperazin-1-yl-3-pyridinyl)-1,3-oxazole-2-carboxamide;5-(1H-indol-5-yl)-N-(4-piperazin-1-yl-3-pyridinyl)-1,3-oxazole-2-carboxamide?

The canonical SMILES for 5-(1H-benzimidazol-2-yl)-N-(4-piperazin-1-yl-3-pyridinyl)-1,3-oxazole-2-carboxamide;5-(1-benzofuran-3-yl)-N-(4-piperazin-1-yl-3-pyridinyl)-1,3-oxazole-2-carboxamide;bis(5-(1H-indazol-3-yl)-N-(4-piperazin-1-yl-3-pyridinyl)-1,3-oxazole-2-carboxamide);5-(1H-indol-3-yl)-N-(4-piperazin-1-yl-3-pyridinyl)-1,3-oxazole-2-carboxamide;5-(1H-indol-5-yl)-N-(4-piperazin-1-yl-3-pyridinyl)-1,3-oxazole-2-carboxamide is O=C(Nc1cnccc1N1CCNCC1)c1ncc(-c2c[nH]c3ccccc23)o1.O=C(Nc1cnccc1N1CCNCC1)c1ncc(-c2ccc3[nH]ccc3c2)o1.O=C(Nc1cnccc1N1CCNCC1)c1ncc(-c2coc3ccccc23)o1.O=C(Nc1cnccc1N1CCNCC1)c1ncc(-c2n[nH]c3ccccc23)o1.O=C(Nc1cnccc1N1CCNCC1)c1ncc(-c2n[nH]c3ccccc23)o1.O=C(Nc1cnccc1N1CCNCC1)c1ncc(-c2nc3ccccc3[nH]2)o1.

What is the InChIKey of 5-(1H-benzimidazol-2-yl)-N-(4-piperazin-1-yl-3-pyridinyl)-1,3-oxazole-2-carboxamide;5-(1-benzofuran-3-yl)-N-(4-piperazin-1-yl-3-pyridinyl)-1,3-oxazole-2-carboxamide;bis(5-(1H-indazol-3-yl)-N-(4-piperazin-1-yl-3-pyridinyl)-1,3-oxazole-2-carboxamide);5-(1H-indol-3-yl)-N-(4-piperazin-1-yl-3-pyridinyl)-1,3-oxazole-2-carboxamide;5-(1H-indol-5-yl)-N-(4-piperazin-1-yl-3-pyridinyl)-1,3-oxazole-2-carboxamide?

The InChIKey is LLCUOIZECDQSNO-UHFFFAOYSA-N. The full InChI is InChI=1S/2C21H20N6O2.C21H19N5O3.3C20H19N7O2/c28-20(26-17-12-23-5-4-18(17)27-9-7-22-8-10-27)21-25-13-19(29-21)15-1-2-16-14(11-15)3-6-24-16;28-20(26-17-12-23-6-5-18(17)27-9-7-22-8-10-27)21-25-13-19(29-21)15-11-24-16-4-2-1-3-14(15)16;27-20(25-16-11-23-6-5-17(16)26-9-7-22-8-10-26)21-24-12-19(29-21)15-13-28-18-4-2-1-3-14(15)18;28-19(26-15-11-22-6-5-16(15)27-9-7-21-8-10-27)20-23-12-17(29-20)18-24-13-3-1-2-4-14(13)25-18;2*28-19(24-15-11-22-6-5-16(15)27-9-7-21-8-10-27)20-23-12-17(29-20)18-13-3-1-2-4-14(13)25-26-18/h2*1-6,11-13,22,24H,7-10H2,(H,26,28);1-6,11-13,22H,7-10H2,(H,25,27);1-6,11-12,21H,7-10H2,(H,24,25)(H,26,28);2*1-6,11-12,21H,7-10H2,(H,24,28)(H,25,26).

What are the key properties of 5-(1H-benzimidazol-2-yl)-N-(4-piperazin-1-yl-3-pyridinyl)-1,3-oxazole-2-carboxamide;5-(1-benzofuran-3-yl)-N-(4-piperazin-1-yl-3-pyridinyl)-1,3-oxazole-2-carboxamide;bis(5-(1H-indazol-3-yl)-N-(4-piperazin-1-yl-3-pyridinyl)-1,3-oxazole-2-carboxamide);5-(1H-indol-3-yl)-N-(4-piperazin-1-yl-3-pyridinyl)-1,3-oxazole-2-carboxamide;5-(1H-indol-5-yl)-N-(4-piperazin-1-yl-3-pyridinyl)-1,3-oxazole-2-carboxamide?

5-(1H-benzimidazol-2-yl)-N-(4-piperazin-1-yl-3-pyridinyl)-1,3-oxazole-2-carboxamide;5-(1-benzofuran-3-yl)-N-(4-piperazin-1-yl-3-pyridinyl)-1,3-oxazole-2-carboxamide;bis(5-(1H-indazol-3-yl)-N-(4-piperazin-1-yl-3-pyridinyl)-1,3-oxazole-2-carboxamide);5-(1H-indol-3-yl)-N-(4-piperazin-1-yl-3-pyridinyl)-1,3-oxazole-2-carboxamide;5-(1H-indol-5-yl)-N-(4-piperazin-1-yl-3-pyridinyl)-1,3-oxazole-2-carboxamide has a molecular weight of 2334.53 g/mol, XLogP of 15.73, 24 rotatable bonds, 17 hydrogen bond donors, and 40 hydrogen bond acceptors.

Where does this data come from?

All data for 5-(1H-benzimidazol-2-yl)-N-(4-piperazin-1-yl-3-pyridinyl)-1,3-oxazole-2-carboxamide;5-(1-benzofuran-3-yl)-N-(4-piperazin-1-yl-3-pyridinyl)-1,3-oxazole-2-carboxamide;bis(5-(1H-indazol-3-yl)-N-(4-piperazin-1-yl-3-pyridinyl)-1,3-oxazole-2-carboxamide);5-(1H-indol-3-yl)-N-(4-piperazin-1-yl-3-pyridinyl)-1,3-oxazole-2-carboxamide;5-(1H-indol-5-yl)-N-(4-piperazin-1-yl-3-pyridinyl)-1,3-oxazole-2-carboxamide is sourced from PubChem (CID 159382757), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).