1-(1-cyclobutylpyrazol-3-yl)sulfonyl-3-[5-(2-methoxy-4-pyridinyl)-2,3-dihydro-1H-inden-4-yl]urea;1-[1-[1-(3-fluoroazetidin-1-yl)-2-methylpropan-2-yl]pyrazol-3-yl]sulfonyl-3-[5-(2-methoxy-4-pyridinyl)-2,3-dihydro-1H-inden-4-yl]urea;1-[5-(2-methoxy-4-pyridinyl)-2,3-dihydro-1H-inden-4-yl]-3-[1-(2-methyl-1-pyrrolidin-1-ylpropan-2-yl)pyrazol-3-yl]sulfonylurea;1-[5-(2-methyl-4-pyridinyl)-2,3-dihydro-1H-inden-4-yl]-3-(1-propan-2-ylpyrazol-3-yl)sulfonylurea;1-(1-propan-2-ylpyrazol-3-yl)sulfonyl-3-(5-pyrimidin-5-yl-2,3-dihydro-1H-inden-4-yl)urea

C118H137FN28O18S5 — CID 159385373

About 1-(1-cyclobutylpyrazol-3-yl)sulfonyl-3-[5-(2-methoxy-4-pyridinyl)-2,3-dihydro-1H-inden-4-yl]urea;1-[1-[1-(3-fluoroazetidin-1-yl)-2-methylpropan-2-yl]pyrazol-3-yl]sulfonyl-3-[5-(2-methoxy-4-pyridinyl)-2,3-dihydro-1H-inden-4-yl]urea;1-[5-(2-methoxy-4-pyridinyl)-2,3-dihydro-1H-inden-4-yl]-3-[1-(2-methyl-1-pyrrolidin-1-ylpropan-2-yl)pyrazol-3-yl]sulfonylurea;1-[5-(2-methyl-4-pyridinyl)-2,3-dihydro-1H-inden-4-yl]-3-(1-propan-2-ylpyrazol-3-yl)sulfonylurea;1-(1-propan-2-ylpyrazol-3-yl)sulfonyl-3-(5-pyrimidin-5-yl-2,3-dihydro-1H-inden-4-yl)urea

1-(1-cyclobutylpyrazol-3-yl)sulfonyl-3-[5-(2-methoxy-4-pyridinyl)-2,3-dihydro-1H-inden-4-yl]urea;1-[1-[1-(3-fluoroazetidin-1-yl)-2-methylpropan-2-yl]pyrazol-3-yl]sulfonyl-3-[5-(2-methoxy-4-pyridinyl)-2,3-dihydro-1H-inden-4-yl]urea;1-[5-(2-methoxy-4-pyridinyl)-2,3-dihydro-1H-inden-4-yl]-3-[1-(2-methyl-1-pyrrolidin-1-ylpropan-2-yl)pyrazol-3-yl]sulfonylurea;1-[5-(2-methyl-4-pyridinyl)-2,3-dihydro-1H-inden-4-yl]-3-(1-propan-2-ylpyrazol-3-yl)sulfonylurea;1-(1-propan-2-ylpyrazol-3-yl)sulfonyl-3-(5-pyrimidin-5-yl-2,3-dihydro-1H-inden-4-yl)urea (PubChem CID 159385373) has the molecular formula C118H137FN28O18S5 and a molecular weight of 2414.90 g/mol. Its IUPAC name is 1-(1-cyclobutylpyrazol-3-yl)sulfonyl-3-[5-(2-methoxy-4-pyridinyl)-2,3-dihydro-1H-inden-4-yl]urea;1-[1-[1-(3-fluoroazetidin-1-yl)-2-methylpropan-2-yl]pyrazol-3-yl]sulfonyl-3-[5-(2-methoxy-4-pyridinyl)-2,3-dihydro-1H-inden-4-yl]urea;1-[5-(2-methoxy-4-pyridinyl)-2,3-dihydro-1H-inden-4-yl]-3-[1-(2-methyl-1-pyrrolidin-1-ylpropan-2-yl)pyrazol-3-yl]sulfonylurea;1-[5-(2-methyl-4-pyridinyl)-2,3-dihydro-1H-inden-4-yl]-3-(1-propan-2-ylpyrazol-3-yl)sulfonylurea;1-(1-propan-2-ylpyrazol-3-yl)sulfonyl-3-(5-pyrimidin-5-yl-2,3-dihydro-1H-inden-4-yl)urea.

Molecular Properties

• Compound Name: 1-(1-cyclobutylpyrazol-3-yl)sulfonyl-3-[5-(2-methoxy-4-pyridinyl)-2,3-dihydro-1H-inden-4-yl]urea;1-[1-[1-(3-fluoroazetidin-1-yl)-2-methylpropan-2-yl]pyrazol-3-yl]sulfonyl-3-[5-(2-methoxy-4-pyridinyl)-2,3-dihydro-1H-inden-4-yl]urea;1-[5-(2-methoxy-4-pyridinyl)-2,3-dihydro-1H-inden-4-yl]-3-[1-(2-methyl-1-pyrrolidin-1-ylpropan-2-yl)pyrazol-3-yl]sulfonylurea;1-[5-(2-methyl-4-pyridinyl)-2,3-dihydro-1H-inden-4-yl]-3-(1-propan-2-ylpyrazol-3-yl)sulfonylurea;1-(1-propan-2-ylpyrazol-3-yl)sulfonyl-3-(5-pyrimidin-5-yl-2,3-dihydro-1H-inden-4-yl)urea
• PubChem CID: 159385373
• Molecular Formula: C118H137FN28O18S5
• Molecular Weight: 2414.90 g/mol
• Exact Mass: 2412.93
• IUPAC Name: 1-(1-cyclobutylpyrazol-3-yl)sulfonyl-3-[5-(2-methoxy-4-pyridinyl)-2,3-dihydro-1H-inden-4-yl]urea;1-[1-[1-(3-fluoroazetidin-1-yl)-2-methylpropan-2-yl]pyrazol-3-yl]sulfonyl-3-[5-(2-methoxy-4-pyridinyl)-2,3-dihydro-1H-inden-4-yl]urea;1-[5-(2-methoxy-4-pyridinyl)-2,3-dihydro-1H-inden-4-yl]-3-[1-(2-methyl-1-pyrrolidin-1-ylpropan-2-yl)pyrazol-3-yl]sulfonylurea;1-[5-(2-methyl-4-pyridinyl)-2,3-dihydro-1H-inden-4-yl]-3-(1-propan-2-ylpyrazol-3-yl)sulfonylurea;1-(1-propan-2-ylpyrazol-3-yl)sulfonyl-3-(5-pyrimidin-5-yl-2,3-dihydro-1H-inden-4-yl)urea
• SMILES: CC(C)n1ccc(S(=O)(=O)NC(=O)Nc2c(-c3cncnc3)ccc3c2CCC3)n1.COc1cc(-c2ccc3c(c2NC(=O)NS(=O)(=O)c2ccn(C(C)(C)CN4CC(F)C4)n2)CCC3)ccn1.COc1cc(-c2ccc3c(c2NC(=O)NS(=O)(=O)c2ccn(C(C)(C)CN4CCCC4)n2)CCC3)ccn1.COc1cc(-c2ccc3c(c2NC(=O)NS(=O)(=O)c2ccn(C4CCC4)n2)CCC3)ccn1.Cc1cc(-c2ccc3c(c2NC(=O)NS(=O)(=O)c2ccn(C(C)C)n2)CCC3)ccn1
• InChI: InChI=1S/C27H34N6O4S.C26H31FN6O4S.C23H25N5O4S.C22H25N5O3S.C20H22N6O3S/c1-27(2,18-32-14-4-5-15-32)33-16-12-24(30-33)38(35,36)31-26(34)29-25-21-8-6-7-19(21)9-10-22(25)20-11-13-28-23(17-20)37-3;1-26(2,16-32-14-19(27)15-32)33-12-10-23(30-33)38(35,36)31-25(34)29-24-20-6-4-5-17(20)7-8-21(24)18-9-11-28-22(13-18)37-3;1-32-20-14-16(10-12-24-20)19-9-8-15-4-2-7-18(15)22(19)25-23(29)27-33(30,31)21-11-13-28(26-21)17-5-3-6-17;1-14(2)27-12-10-20(25-27)31(29,30)26-22(28)24-21-18-6-4-5-16(18)7-8-19(21)17-9-11-23-15(3)13-17;1-13(2)26-9-8-18(24-26)30(28,29)25-20(27)23-19-16-5-3-4-14(16)6-7-17(19)15-10-21-12-22-11-15/h9-13,16-17H,4-8,14-15,18H2,1-3H3,(H2,29,31,34);7-13,19H,4-6,14-16H2,1-3H3,(H2,29,31,34);8-14,17H,2-7H2,1H3,(H2,25,27,29);7-14H,4-6H2,1-3H3,(H2,24,26,28);6-13H,3-5H2,1-2H3,(H2,23,25,27)
• InChIKey: LLKRNVLFYYKBJN-UHFFFAOYSA-N
• XLogP: 17.56
• TPSA: 576.96 Ų
• H-Bond Donors: 10
• H-Bond Acceptors: 36
• Rotatable Bonds: 32
• Heavy Atoms: 170
• Complexity: —

Lipinski Rule of Five

4 violations

Rule	Value
MW ≤ 500	2414.90
LogP ≤ 5	17.56
H-Bond Donors ≤ 5	10
H-Bond Acceptors ≤ 10	36

Frequently Asked Questions

What is the IUPAC name of 1-(1-cyclobutylpyrazol-3-yl)sulfonyl-3-[5-(2-methoxy-4-pyridinyl)-2,3-dihydro-1H-inden-4-yl]urea;1-[1-[1-(3-fluoroazetidin-1-yl)-2-methylpropan-2-yl]pyrazol-3-yl]sulfonyl-3-[5-(2-methoxy-4-pyridinyl)-2,3-dihydro-1H-inden-4-yl]urea;1-[5-(2-methoxy-4-pyridinyl)-2,3-dihydro-1H-inden-4-yl]-3-[1-(2-methyl-1-pyrrolidin-1-ylpropan-2-yl)pyrazol-3-yl]sulfonylurea;1-[5-(2-methyl-4-pyridinyl)-2,3-dihydro-1H-inden-4-yl]-3-(1-propan-2-ylpyrazol-3-yl)sulfonylurea;1-(1-propan-2-ylpyrazol-3-yl)sulfonyl-3-(5-pyrimidin-5-yl-2,3-dihydro-1H-inden-4-yl)urea?

The IUPAC name of 1-(1-cyclobutylpyrazol-3-yl)sulfonyl-3-[5-(2-methoxy-4-pyridinyl)-2,3-dihydro-1H-inden-4-yl]urea;1-[1-[1-(3-fluoroazetidin-1-yl)-2-methylpropan-2-yl]pyrazol-3-yl]sulfonyl-3-[5-(2-methoxy-4-pyridinyl)-2,3-dihydro-1H-inden-4-yl]urea;1-[5-(2-methoxy-4-pyridinyl)-2,3-dihydro-1H-inden-4-yl]-3-[1-(2-methyl-1-pyrrolidin-1-ylpropan-2-yl)pyrazol-3-yl]sulfonylurea;1-[5-(2-methyl-4-pyridinyl)-2,3-dihydro-1H-inden-4-yl]-3-(1-propan-2-ylpyrazol-3-yl)sulfonylurea;1-(1-propan-2-ylpyrazol-3-yl)sulfonyl-3-(5-pyrimidin-5-yl-2,3-dihydro-1H-inden-4-yl)urea (CID 159385373) is 1-(1-cyclobutylpyrazol-3-yl)sulfonyl-3-[5-(2-methoxy-4-pyridinyl)-2,3-dihydro-1H-inden-4-yl]urea;1-[1-[1-(3-fluoroazetidin-1-yl)-2-methylpropan-2-yl]pyrazol-3-yl]sulfonyl-3-[5-(2-methoxy-4-pyridinyl)-2,3-dihydro-1H-inden-4-yl]urea;1-[5-(2-methoxy-4-pyridinyl)-2,3-dihydro-1H-inden-4-yl]-3-[1-(2-methyl-1-pyrrolidin-1-ylpropan-2-yl)pyrazol-3-yl]sulfonylurea;1-[5-(2-methyl-4-pyridinyl)-2,3-dihydro-1H-inden-4-yl]-3-(1-propan-2-ylpyrazol-3-yl)sulfonylurea;1-(1-propan-2-ylpyrazol-3-yl)sulfonyl-3-(5-pyrimidin-5-yl-2,3-dihydro-1H-inden-4-yl)urea.

What is the SMILES notation for 1-(1-cyclobutylpyrazol-3-yl)sulfonyl-3-[5-(2-methoxy-4-pyridinyl)-2,3-dihydro-1H-inden-4-yl]urea;1-[1-[1-(3-fluoroazetidin-1-yl)-2-methylpropan-2-yl]pyrazol-3-yl]sulfonyl-3-[5-(2-methoxy-4-pyridinyl)-2,3-dihydro-1H-inden-4-yl]urea;1-[5-(2-methoxy-4-pyridinyl)-2,3-dihydro-1H-inden-4-yl]-3-[1-(2-methyl-1-pyrrolidin-1-ylpropan-2-yl)pyrazol-3-yl]sulfonylurea;1-[5-(2-methyl-4-pyridinyl)-2,3-dihydro-1H-inden-4-yl]-3-(1-propan-2-ylpyrazol-3-yl)sulfonylurea;1-(1-propan-2-ylpyrazol-3-yl)sulfonyl-3-(5-pyrimidin-5-yl-2,3-dihydro-1H-inden-4-yl)urea?

The canonical SMILES for 1-(1-cyclobutylpyrazol-3-yl)sulfonyl-3-[5-(2-methoxy-4-pyridinyl)-2,3-dihydro-1H-inden-4-yl]urea;1-[1-[1-(3-fluoroazetidin-1-yl)-2-methylpropan-2-yl]pyrazol-3-yl]sulfonyl-3-[5-(2-methoxy-4-pyridinyl)-2,3-dihydro-1H-inden-4-yl]urea;1-[5-(2-methoxy-4-pyridinyl)-2,3-dihydro-1H-inden-4-yl]-3-[1-(2-methyl-1-pyrrolidin-1-ylpropan-2-yl)pyrazol-3-yl]sulfonylurea;1-[5-(2-methyl-4-pyridinyl)-2,3-dihydro-1H-inden-4-yl]-3-(1-propan-2-ylpyrazol-3-yl)sulfonylurea;1-(1-propan-2-ylpyrazol-3-yl)sulfonyl-3-(5-pyrimidin-5-yl-2,3-dihydro-1H-inden-4-yl)urea is CC(C)n1ccc(S(=O)(=O)NC(=O)Nc2c(-c3cncnc3)ccc3c2CCC3)n1.COc1cc(-c2ccc3c(c2NC(=O)NS(=O)(=O)c2ccn(C(C)(C)CN4CC(F)C4)n2)CCC3)ccn1.COc1cc(-c2ccc3c(c2NC(=O)NS(=O)(=O)c2ccn(C(C)(C)CN4CCCC4)n2)CCC3)ccn1.COc1cc(-c2ccc3c(c2NC(=O)NS(=O)(=O)c2ccn(C4CCC4)n2)CCC3)ccn1.Cc1cc(-c2ccc3c(c2NC(=O)NS(=O)(=O)c2ccn(C(C)C)n2)CCC3)ccn1.

What is the InChIKey of 1-(1-cyclobutylpyrazol-3-yl)sulfonyl-3-[5-(2-methoxy-4-pyridinyl)-2,3-dihydro-1H-inden-4-yl]urea;1-[1-[1-(3-fluoroazetidin-1-yl)-2-methylpropan-2-yl]pyrazol-3-yl]sulfonyl-3-[5-(2-methoxy-4-pyridinyl)-2,3-dihydro-1H-inden-4-yl]urea;1-[5-(2-methoxy-4-pyridinyl)-2,3-dihydro-1H-inden-4-yl]-3-[1-(2-methyl-1-pyrrolidin-1-ylpropan-2-yl)pyrazol-3-yl]sulfonylurea;1-[5-(2-methyl-4-pyridinyl)-2,3-dihydro-1H-inden-4-yl]-3-(1-propan-2-ylpyrazol-3-yl)sulfonylurea;1-(1-propan-2-ylpyrazol-3-yl)sulfonyl-3-(5-pyrimidin-5-yl-2,3-dihydro-1H-inden-4-yl)urea?

The InChIKey is LLKRNVLFYYKBJN-UHFFFAOYSA-N. The full InChI is InChI=1S/C27H34N6O4S.C26H31FN6O4S.C23H25N5O4S.C22H25N5O3S.C20H22N6O3S/c1-27(2,18-32-14-4-5-15-32)33-16-12-24(30-33)38(35,36)31-26(34)29-25-21-8-6-7-19(21)9-10-22(25)20-11-13-28-23(17-20)37-3;1-26(2,16-32-14-19(27)15-32)33-12-10-23(30-33)38(35,36)31-25(34)29-24-20-6-4-5-17(20)7-8-21(24)18-9-11-28-22(13-18)37-3;1-32-20-14-16(10-12-24-20)19-9-8-15-4-2-7-18(15)22(19)25-23(29)27-33(30,31)21-11-13-28(26-21)17-5-3-6-17;1-14(2)27-12-10-20(25-27)31(29,30)26-22(28)24-21-18-6-4-5-16(18)7-8-19(21)17-9-11-23-15(3)13-17;1-13(2)26-9-8-18(24-26)30(28,29)25-20(27)23-19-16-5-3-4-14(16)6-7-17(19)15-10-21-12-22-11-15/h9-13,16-17H,4-8,14-15,18H2,1-3H3,(H2,29,31,34);7-13,19H,4-6,14-16H2,1-3H3,(H2,29,31,34);8-14,17H,2-7H2,1H3,(H2,25,27,29);7-14H,4-6H2,1-3H3,(H2,24,26,28);6-13H,3-5H2,1-2H3,(H2,23,25,27).

What are the key properties of 1-(1-cyclobutylpyrazol-3-yl)sulfonyl-3-[5-(2-methoxy-4-pyridinyl)-2,3-dihydro-1H-inden-4-yl]urea;1-[1-[1-(3-fluoroazetidin-1-yl)-2-methylpropan-2-yl]pyrazol-3-yl]sulfonyl-3-[5-(2-methoxy-4-pyridinyl)-2,3-dihydro-1H-inden-4-yl]urea;1-[5-(2-methoxy-4-pyridinyl)-2,3-dihydro-1H-inden-4-yl]-3-[1-(2-methyl-1-pyrrolidin-1-ylpropan-2-yl)pyrazol-3-yl]sulfonylurea;1-[5-(2-methyl-4-pyridinyl)-2,3-dihydro-1H-inden-4-yl]-3-(1-propan-2-ylpyrazol-3-yl)sulfonylurea;1-(1-propan-2-ylpyrazol-3-yl)sulfonyl-3-(5-pyrimidin-5-yl-2,3-dihydro-1H-inden-4-yl)urea?

1-(1-cyclobutylpyrazol-3-yl)sulfonyl-3-[5-(2-methoxy-4-pyridinyl)-2,3-dihydro-1H-inden-4-yl]urea;1-[1-[1-(3-fluoroazetidin-1-yl)-2-methylpropan-2-yl]pyrazol-3-yl]sulfonyl-3-[5-(2-methoxy-4-pyridinyl)-2,3-dihydro-1H-inden-4-yl]urea;1-[5-(2-methoxy-4-pyridinyl)-2,3-dihydro-1H-inden-4-yl]-3-[1-(2-methyl-1-pyrrolidin-1-ylpropan-2-yl)pyrazol-3-yl]sulfonylurea;1-[5-(2-methyl-4-pyridinyl)-2,3-dihydro-1H-inden-4-yl]-3-(1-propan-2-ylpyrazol-3-yl)sulfonylurea;1-(1-propan-2-ylpyrazol-3-yl)sulfonyl-3-(5-pyrimidin-5-yl-2,3-dihydro-1H-inden-4-yl)urea has a molecular weight of 2414.90 g/mol, XLogP of 17.56, 32 rotatable bonds, 10 hydrogen bond donors, and 36 hydrogen bond acceptors.

Where does this data come from?

All data for 1-(1-cyclobutylpyrazol-3-yl)sulfonyl-3-[5-(2-methoxy-4-pyridinyl)-2,3-dihydro-1H-inden-4-yl]urea;1-[1-[1-(3-fluoroazetidin-1-yl)-2-methylpropan-2-yl]pyrazol-3-yl]sulfonyl-3-[5-(2-methoxy-4-pyridinyl)-2,3-dihydro-1H-inden-4-yl]urea;1-[5-(2-methoxy-4-pyridinyl)-2,3-dihydro-1H-inden-4-yl]-3-[1-(2-methyl-1-pyrrolidin-1-ylpropan-2-yl)pyrazol-3-yl]sulfonylurea;1-[5-(2-methyl-4-pyridinyl)-2,3-dihydro-1H-inden-4-yl]-3-(1-propan-2-ylpyrazol-3-yl)sulfonylurea;1-(1-propan-2-ylpyrazol-3-yl)sulfonyl-3-(5-pyrimidin-5-yl-2,3-dihydro-1H-inden-4-yl)urea is sourced from PubChem (CID 159385373), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).