2,4-difluoro-N-[5-[2-(1-methylpyrazol-4-yl)-5-propan-2-yl-1,3-thiazol-4-yl]-2-pyridinyl]benzamide;2,6-difluoro-N-[5-[3-methyl-5-(pyridine-3-carbonyl)thiophen-2-yl]-2-pyridinyl]benzamide;2,6-difluoro-N-[5-(5-methyl-2-pyridin-2-yl-1,3-thiazol-4-yl)-2-pyridinyl]benzamide;2,6-difluoro-N-[5-(5-methyl-2-pyridin-3-yl-1,3-thiazol-4-yl)-2-pyridinyl]benzamide;2,4-difluoro-N-[5-(5-propan-2-yl-2-pyridin-3-yl-1,3-thiazol-4-yl)-2-pyridinyl]benzamide;2,6-difluoro-N-[5-(5-propan-2-yl-2-pyridin-3-yl-1,3-thiazol-4-yl)-2-pyridinyl]benzamide

C133H98F12N24O7S6 — CID 159387873

About 2,4-difluoro-N-[5-[2-(1-methylpyrazol-4-yl)-5-propan-2-yl-1,3-thiazol-4-yl]-2-pyridinyl]benzamide;2,6-difluoro-N-[5-[3-methyl-5-(pyridine-3-carbonyl)thiophen-2-yl]-2-pyridinyl]benzamide;2,6-difluoro-N-[5-(5-methyl-2-pyridin-2-yl-1,3-thiazol-4-yl)-2-pyridinyl]benzamide;2,6-difluoro-N-[5-(5-methyl-2-pyridin-3-yl-1,3-thiazol-4-yl)-2-pyridinyl]benzamide;2,4-difluoro-N-[5-(5-propan-2-yl-2-pyridin-3-yl-1,3-thiazol-4-yl)-2-pyridinyl]benzamide;2,6-difluoro-N-[5-(5-propan-2-yl-2-pyridin-3-yl-1,3-thiazol-4-yl)-2-pyridinyl]benzamide

2,4-difluoro-N-[5-[2-(1-methylpyrazol-4-yl)-5-propan-2-yl-1,3-thiazol-4-yl]-2-pyridinyl]benzamide;2,6-difluoro-N-[5-[3-methyl-5-(pyridine-3-carbonyl)thiophen-2-yl]-2-pyridinyl]benzamide;2,6-difluoro-N-[5-(5-methyl-2-pyridin-2-yl-1,3-thiazol-4-yl)-2-pyridinyl]benzamide;2,6-difluoro-N-[5-(5-methyl-2-pyridin-3-yl-1,3-thiazol-4-yl)-2-pyridinyl]benzamide;2,4-difluoro-N-[5-(5-propan-2-yl-2-pyridin-3-yl-1,3-thiazol-4-yl)-2-pyridinyl]benzamide;2,6-difluoro-N-[5-(5-propan-2-yl-2-pyridin-3-yl-1,3-thiazol-4-yl)-2-pyridinyl]benzamide (PubChem CID 159387873) has the molecular formula C133H98F12N24O7S6 and a molecular weight of 2564.79 g/mol. Its IUPAC name is 2,4-difluoro-N-[5-[2-(1-methylpyrazol-4-yl)-5-propan-2-yl-1,3-thiazol-4-yl]-2-pyridinyl]benzamide;2,6-difluoro-N-[5-[3-methyl-5-(pyridine-3-carbonyl)thiophen-2-yl]-2-pyridinyl]benzamide;2,6-difluoro-N-[5-(5-methyl-2-pyridin-2-yl-1,3-thiazol-4-yl)-2-pyridinyl]benzamide;2,6-difluoro-N-[5-(5-methyl-2-pyridin-3-yl-1,3-thiazol-4-yl)-2-pyridinyl]benzamide;2,4-difluoro-N-[5-(5-propan-2-yl-2-pyridin-3-yl-1,3-thiazol-4-yl)-2-pyridinyl]benzamide;2,6-difluoro-N-[5-(5-propan-2-yl-2-pyridin-3-yl-1,3-thiazol-4-yl)-2-pyridinyl]benzamide.

Molecular Properties

• Compound Name: 2,4-difluoro-N-[5-[2-(1-methylpyrazol-4-yl)-5-propan-2-yl-1,3-thiazol-4-yl]-2-pyridinyl]benzamide;2,6-difluoro-N-[5-[3-methyl-5-(pyridine-3-carbonyl)thiophen-2-yl]-2-pyridinyl]benzamide;2,6-difluoro-N-[5-(5-methyl-2-pyridin-2-yl-1,3-thiazol-4-yl)-2-pyridinyl]benzamide;2,6-difluoro-N-[5-(5-methyl-2-pyridin-3-yl-1,3-thiazol-4-yl)-2-pyridinyl]benzamide;2,4-difluoro-N-[5-(5-propan-2-yl-2-pyridin-3-yl-1,3-thiazol-4-yl)-2-pyridinyl]benzamide;2,6-difluoro-N-[5-(5-propan-2-yl-2-pyridin-3-yl-1,3-thiazol-4-yl)-2-pyridinyl]benzamide
• PubChem CID: 159387873
• Molecular Formula: C133H98F12N24O7S6
• Molecular Weight: 2564.79 g/mol
• Exact Mass: 2562.62
• IUPAC Name: 2,4-difluoro-N-[5-[2-(1-methylpyrazol-4-yl)-5-propan-2-yl-1,3-thiazol-4-yl]-2-pyridinyl]benzamide;2,6-difluoro-N-[5-[3-methyl-5-(pyridine-3-carbonyl)thiophen-2-yl]-2-pyridinyl]benzamide;2,6-difluoro-N-[5-(5-methyl-2-pyridin-2-yl-1,3-thiazol-4-yl)-2-pyridinyl]benzamide;2,6-difluoro-N-[5-(5-methyl-2-pyridin-3-yl-1,3-thiazol-4-yl)-2-pyridinyl]benzamide;2,4-difluoro-N-[5-(5-propan-2-yl-2-pyridin-3-yl-1,3-thiazol-4-yl)-2-pyridinyl]benzamide;2,6-difluoro-N-[5-(5-propan-2-yl-2-pyridin-3-yl-1,3-thiazol-4-yl)-2-pyridinyl]benzamide
• SMILES: CC(C)c1sc(-c2cccnc2)nc1-c1ccc(NC(=O)c2c(F)cccc2F)nc1.CC(C)c1sc(-c2cccnc2)nc1-c1ccc(NC(=O)c2ccc(F)cc2F)nc1.CC(C)c1sc(-c2cnn(C)c2)nc1-c1ccc(NC(=O)c2ccc(F)cc2F)nc1.Cc1cc(C(=O)c2cccnc2)sc1-c1ccc(NC(=O)c2c(F)cccc2F)nc1.Cc1sc(-c2ccccn2)nc1-c1ccc(NC(=O)c2c(F)cccc2F)nc1.Cc1sc(-c2cccnc2)nc1-c1ccc(NC(=O)c2c(F)cccc2F)nc1
• InChI: InChI=1S/2C23H18F2N4OS.C23H15F2N3O2S.C22H19F2N5OS.2C21H14F2N4OS/c1-13(2)21-20(29-23(31-21)15-5-4-10-26-11-15)14-8-9-18(27-12-14)28-22(30)19-16(24)6-3-7-17(19)25;1-13(2)21-20(29-23(31-21)15-4-3-9-26-11-15)14-5-8-19(27-12-14)28-22(30)17-7-6-16(24)10-18(17)25;1-13-10-18(21(29)14-4-3-9-26-11-14)31-22(13)15-7-8-19(27-12-15)28-23(30)20-16(24)5-2-6-17(20)25;1-12(2)20-19(28-22(31-20)14-10-26-29(3)11-14)13-4-7-18(25-9-13)27-21(30)16-6-5-15(23)8-17(16)24;1-12-19(27-21(29-12)14-4-3-9-24-10-14)13-7-8-17(25-11-13)26-20(28)18-15(22)5-2-6-16(18)23;1-12-19(27-21(29-12)16-7-2-3-10-24-16)13-8-9-17(25-11-13)26-20(28)18-14(22)5-4-6-15(18)23/h2*3-13H,1-2H3,(H,27,28,30);2-12H,1H3,(H,27,28,30);4-12H,1-3H3,(H,25,27,30);2*2-11H,1H3,(H,25,26,28)
• InChIKey: LLSRLICHAWIMJU-UHFFFAOYSA-N
• XLogP: 32.59
• TPSA: 415.73 Ų
• H-Bond Donors: 6
• H-Bond Acceptors: 31
• Rotatable Bonds: 28
• Heavy Atoms: 182
• Complexity: —

Lipinski Rule of Five

4 violations

Rule	Value
MW ≤ 500	2564.79
LogP ≤ 5	32.59
H-Bond Donors ≤ 5	6
H-Bond Acceptors ≤ 10	31

Frequently Asked Questions

What is the IUPAC name of 2,4-difluoro-N-[5-[2-(1-methylpyrazol-4-yl)-5-propan-2-yl-1,3-thiazol-4-yl]-2-pyridinyl]benzamide;2,6-difluoro-N-[5-[3-methyl-5-(pyridine-3-carbonyl)thiophen-2-yl]-2-pyridinyl]benzamide;2,6-difluoro-N-[5-(5-methyl-2-pyridin-2-yl-1,3-thiazol-4-yl)-2-pyridinyl]benzamide;2,6-difluoro-N-[5-(5-methyl-2-pyridin-3-yl-1,3-thiazol-4-yl)-2-pyridinyl]benzamide;2,4-difluoro-N-[5-(5-propan-2-yl-2-pyridin-3-yl-1,3-thiazol-4-yl)-2-pyridinyl]benzamide;2,6-difluoro-N-[5-(5-propan-2-yl-2-pyridin-3-yl-1,3-thiazol-4-yl)-2-pyridinyl]benzamide?

The IUPAC name of 2,4-difluoro-N-[5-[2-(1-methylpyrazol-4-yl)-5-propan-2-yl-1,3-thiazol-4-yl]-2-pyridinyl]benzamide;2,6-difluoro-N-[5-[3-methyl-5-(pyridine-3-carbonyl)thiophen-2-yl]-2-pyridinyl]benzamide;2,6-difluoro-N-[5-(5-methyl-2-pyridin-2-yl-1,3-thiazol-4-yl)-2-pyridinyl]benzamide;2,6-difluoro-N-[5-(5-methyl-2-pyridin-3-yl-1,3-thiazol-4-yl)-2-pyridinyl]benzamide;2,4-difluoro-N-[5-(5-propan-2-yl-2-pyridin-3-yl-1,3-thiazol-4-yl)-2-pyridinyl]benzamide;2,6-difluoro-N-[5-(5-propan-2-yl-2-pyridin-3-yl-1,3-thiazol-4-yl)-2-pyridinyl]benzamide (CID 159387873) is 2,4-difluoro-N-[5-[2-(1-methylpyrazol-4-yl)-5-propan-2-yl-1,3-thiazol-4-yl]-2-pyridinyl]benzamide;2,6-difluoro-N-[5-[3-methyl-5-(pyridine-3-carbonyl)thiophen-2-yl]-2-pyridinyl]benzamide;2,6-difluoro-N-[5-(5-methyl-2-pyridin-2-yl-1,3-thiazol-4-yl)-2-pyridinyl]benzamide;2,6-difluoro-N-[5-(5-methyl-2-pyridin-3-yl-1,3-thiazol-4-yl)-2-pyridinyl]benzamide;2,4-difluoro-N-[5-(5-propan-2-yl-2-pyridin-3-yl-1,3-thiazol-4-yl)-2-pyridinyl]benzamide;2,6-difluoro-N-[5-(5-propan-2-yl-2-pyridin-3-yl-1,3-thiazol-4-yl)-2-pyridinyl]benzamide.

What is the SMILES notation for 2,4-difluoro-N-[5-[2-(1-methylpyrazol-4-yl)-5-propan-2-yl-1,3-thiazol-4-yl]-2-pyridinyl]benzamide;2,6-difluoro-N-[5-[3-methyl-5-(pyridine-3-carbonyl)thiophen-2-yl]-2-pyridinyl]benzamide;2,6-difluoro-N-[5-(5-methyl-2-pyridin-2-yl-1,3-thiazol-4-yl)-2-pyridinyl]benzamide;2,6-difluoro-N-[5-(5-methyl-2-pyridin-3-yl-1,3-thiazol-4-yl)-2-pyridinyl]benzamide;2,4-difluoro-N-[5-(5-propan-2-yl-2-pyridin-3-yl-1,3-thiazol-4-yl)-2-pyridinyl]benzamide;2,6-difluoro-N-[5-(5-propan-2-yl-2-pyridin-3-yl-1,3-thiazol-4-yl)-2-pyridinyl]benzamide?

The canonical SMILES for 2,4-difluoro-N-[5-[2-(1-methylpyrazol-4-yl)-5-propan-2-yl-1,3-thiazol-4-yl]-2-pyridinyl]benzamide;2,6-difluoro-N-[5-[3-methyl-5-(pyridine-3-carbonyl)thiophen-2-yl]-2-pyridinyl]benzamide;2,6-difluoro-N-[5-(5-methyl-2-pyridin-2-yl-1,3-thiazol-4-yl)-2-pyridinyl]benzamide;2,6-difluoro-N-[5-(5-methyl-2-pyridin-3-yl-1,3-thiazol-4-yl)-2-pyridinyl]benzamide;2,4-difluoro-N-[5-(5-propan-2-yl-2-pyridin-3-yl-1,3-thiazol-4-yl)-2-pyridinyl]benzamide;2,6-difluoro-N-[5-(5-propan-2-yl-2-pyridin-3-yl-1,3-thiazol-4-yl)-2-pyridinyl]benzamide is CC(C)c1sc(-c2cccnc2)nc1-c1ccc(NC(=O)c2c(F)cccc2F)nc1.CC(C)c1sc(-c2cccnc2)nc1-c1ccc(NC(=O)c2ccc(F)cc2F)nc1.CC(C)c1sc(-c2cnn(C)c2)nc1-c1ccc(NC(=O)c2ccc(F)cc2F)nc1.Cc1cc(C(=O)c2cccnc2)sc1-c1ccc(NC(=O)c2c(F)cccc2F)nc1.Cc1sc(-c2ccccn2)nc1-c1ccc(NC(=O)c2c(F)cccc2F)nc1.Cc1sc(-c2cccnc2)nc1-c1ccc(NC(=O)c2c(F)cccc2F)nc1.

What is the InChIKey of 2,4-difluoro-N-[5-[2-(1-methylpyrazol-4-yl)-5-propan-2-yl-1,3-thiazol-4-yl]-2-pyridinyl]benzamide;2,6-difluoro-N-[5-[3-methyl-5-(pyridine-3-carbonyl)thiophen-2-yl]-2-pyridinyl]benzamide;2,6-difluoro-N-[5-(5-methyl-2-pyridin-2-yl-1,3-thiazol-4-yl)-2-pyridinyl]benzamide;2,6-difluoro-N-[5-(5-methyl-2-pyridin-3-yl-1,3-thiazol-4-yl)-2-pyridinyl]benzamide;2,4-difluoro-N-[5-(5-propan-2-yl-2-pyridin-3-yl-1,3-thiazol-4-yl)-2-pyridinyl]benzamide;2,6-difluoro-N-[5-(5-propan-2-yl-2-pyridin-3-yl-1,3-thiazol-4-yl)-2-pyridinyl]benzamide?

The InChIKey is LLSRLICHAWIMJU-UHFFFAOYSA-N. The full InChI is InChI=1S/2C23H18F2N4OS.C23H15F2N3O2S.C22H19F2N5OS.2C21H14F2N4OS/c1-13(2)21-20(29-23(31-21)15-5-4-10-26-11-15)14-8-9-18(27-12-14)28-22(30)19-16(24)6-3-7-17(19)25;1-13(2)21-20(29-23(31-21)15-4-3-9-26-11-15)14-5-8-19(27-12-14)28-22(30)17-7-6-16(24)10-18(17)25;1-13-10-18(21(29)14-4-3-9-26-11-14)31-22(13)15-7-8-19(27-12-15)28-23(30)20-16(24)5-2-6-17(20)25;1-12(2)20-19(28-22(31-20)14-10-26-29(3)11-14)13-4-7-18(25-9-13)27-21(30)16-6-5-15(23)8-17(16)24;1-12-19(27-21(29-12)14-4-3-9-24-10-14)13-7-8-17(25-11-13)26-20(28)18-15(22)5-2-6-16(18)23;1-12-19(27-21(29-12)16-7-2-3-10-24-16)13-8-9-17(25-11-13)26-20(28)18-14(22)5-4-6-15(18)23/h2*3-13H,1-2H3,(H,27,28,30);2-12H,1H3,(H,27,28,30);4-12H,1-3H3,(H,25,27,30);2*2-11H,1H3,(H,25,26,28).

What are the key properties of 2,4-difluoro-N-[5-[2-(1-methylpyrazol-4-yl)-5-propan-2-yl-1,3-thiazol-4-yl]-2-pyridinyl]benzamide;2,6-difluoro-N-[5-[3-methyl-5-(pyridine-3-carbonyl)thiophen-2-yl]-2-pyridinyl]benzamide;2,6-difluoro-N-[5-(5-methyl-2-pyridin-2-yl-1,3-thiazol-4-yl)-2-pyridinyl]benzamide;2,6-difluoro-N-[5-(5-methyl-2-pyridin-3-yl-1,3-thiazol-4-yl)-2-pyridinyl]benzamide;2,4-difluoro-N-[5-(5-propan-2-yl-2-pyridin-3-yl-1,3-thiazol-4-yl)-2-pyridinyl]benzamide;2,6-difluoro-N-[5-(5-propan-2-yl-2-pyridin-3-yl-1,3-thiazol-4-yl)-2-pyridinyl]benzamide?

2,4-difluoro-N-[5-[2-(1-methylpyrazol-4-yl)-5-propan-2-yl-1,3-thiazol-4-yl]-2-pyridinyl]benzamide;2,6-difluoro-N-[5-[3-methyl-5-(pyridine-3-carbonyl)thiophen-2-yl]-2-pyridinyl]benzamide;2,6-difluoro-N-[5-(5-methyl-2-pyridin-2-yl-1,3-thiazol-4-yl)-2-pyridinyl]benzamide;2,6-difluoro-N-[5-(5-methyl-2-pyridin-3-yl-1,3-thiazol-4-yl)-2-pyridinyl]benzamide;2,4-difluoro-N-[5-(5-propan-2-yl-2-pyridin-3-yl-1,3-thiazol-4-yl)-2-pyridinyl]benzamide;2,6-difluoro-N-[5-(5-propan-2-yl-2-pyridin-3-yl-1,3-thiazol-4-yl)-2-pyridinyl]benzamide has a molecular weight of 2564.79 g/mol, XLogP of 32.59, 28 rotatable bonds, 6 hydrogen bond donors, and 31 hydrogen bond acceptors.

Where does this data come from?

All data for 2,4-difluoro-N-[5-[2-(1-methylpyrazol-4-yl)-5-propan-2-yl-1,3-thiazol-4-yl]-2-pyridinyl]benzamide;2,6-difluoro-N-[5-[3-methyl-5-(pyridine-3-carbonyl)thiophen-2-yl]-2-pyridinyl]benzamide;2,6-difluoro-N-[5-(5-methyl-2-pyridin-2-yl-1,3-thiazol-4-yl)-2-pyridinyl]benzamide;2,6-difluoro-N-[5-(5-methyl-2-pyridin-3-yl-1,3-thiazol-4-yl)-2-pyridinyl]benzamide;2,4-difluoro-N-[5-(5-propan-2-yl-2-pyridin-3-yl-1,3-thiazol-4-yl)-2-pyridinyl]benzamide;2,6-difluoro-N-[5-(5-propan-2-yl-2-pyridin-3-yl-1,3-thiazol-4-yl)-2-pyridinyl]benzamide is sourced from PubChem (CID 159387873), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).