2-(4-methylidene-2-oxocyclohexyl)-4-[[6-(morpholin-4-ylmethyl)imidazo[1,2-a]pyridin-2-yl]methoxy]isoindole-1,3-dione;2-(6-methylidene-2-oxopiperidin-3-yl)-4-[[2-(morpholin-4-ylmethyl)imidazo[1,2-a]pyridin-6-yl]methoxy]-3H-isoindol-1-one;2-(6-methylidene-2-oxopiperidin-3-yl)-4-[[5-(morpholin-4-ylmethyl)-1,2-oxazol-3-yl]methoxy]-3H-isoindol-1-one;2-(6-methylidene-2-oxopiperidin-3-yl)-4-[[5-(morpholin-4-ylmethyl)-2-pyridinyl]methoxy]-3H-isoindol-1-one;2-(6-methylidene-2-oxopiperidin-3-yl)-4-[[3-[(4-propan-2-ylpiperidin-1-yl)methyl]-1,2-oxazol-5-yl]methoxy]-3H-isoindol-1-one

C130H145N21O22 — CID 159395369

About 2-(4-methylidene-2-oxocyclohexyl)-4-[[6-(morpholin-4-ylmethyl)imidazo[1,2-a]pyridin-2-yl]methoxy]isoindole-1,3-dione;2-(6-methylidene-2-oxopiperidin-3-yl)-4-[[2-(morpholin-4-ylmethyl)imidazo[1,2-a]pyridin-6-yl]methoxy]-3H-isoindol-1-one;2-(6-methylidene-2-oxopiperidin-3-yl)-4-[[5-(morpholin-4-ylmethyl)-1,2-oxazol-3-yl]methoxy]-3H-isoindol-1-one;2-(6-methylidene-2-oxopiperidin-3-yl)-4-[[5-(morpholin-4-ylmethyl)-2-pyridinyl]methoxy]-3H-isoindol-1-one;2-(6-methylidene-2-oxopiperidin-3-yl)-4-[[3-[(4-propan-2-ylpiperidin-1-yl)methyl]-1,2-oxazol-5-yl]methoxy]-3H-isoindol-1-one

2-(4-methylidene-2-oxocyclohexyl)-4-[[6-(morpholin-4-ylmethyl)imidazo[1,2-a]pyridin-2-yl]methoxy]isoindole-1,3-dione;2-(6-methylidene-2-oxopiperidin-3-yl)-4-[[2-(morpholin-4-ylmethyl)imidazo[1,2-a]pyridin-6-yl]methoxy]-3H-isoindol-1-one;2-(6-methylidene-2-oxopiperidin-3-yl)-4-[[5-(morpholin-4-ylmethyl)-1,2-oxazol-3-yl]methoxy]-3H-isoindol-1-one;2-(6-methylidene-2-oxopiperidin-3-yl)-4-[[5-(morpholin-4-ylmethyl)-2-pyridinyl]methoxy]-3H-isoindol-1-one;2-(6-methylidene-2-oxopiperidin-3-yl)-4-[[3-[(4-propan-2-ylpiperidin-1-yl)methyl]-1,2-oxazol-5-yl]methoxy]-3H-isoindol-1-one (PubChem CID 159395369) has the molecular formula C130H145N21O22 and a molecular weight of 2353.71 g/mol. Its IUPAC name is 2-(4-methylidene-2-oxocyclohexyl)-4-[[6-(morpholin-4-ylmethyl)imidazo[1,2-a]pyridin-2-yl]methoxy]isoindole-1,3-dione;2-(6-methylidene-2-oxopiperidin-3-yl)-4-[[2-(morpholin-4-ylmethyl)imidazo[1,2-a]pyridin-6-yl]methoxy]-3H-isoindol-1-one;2-(6-methylidene-2-oxopiperidin-3-yl)-4-[[5-(morpholin-4-ylmethyl)-1,2-oxazol-3-yl]methoxy]-3H-isoindol-1-one;2-(6-methylidene-2-oxopiperidin-3-yl)-4-[[5-(morpholin-4-ylmethyl)-2-pyridinyl]methoxy]-3H-isoindol-1-one;2-(6-methylidene-2-oxopiperidin-3-yl)-4-[[3-[(4-propan-2-ylpiperidin-1-yl)methyl]-1,2-oxazol-5-yl]methoxy]-3H-isoindol-1-one.

Molecular Properties

• Compound Name: 2-(4-methylidene-2-oxocyclohexyl)-4-[[6-(morpholin-4-ylmethyl)imidazo[1,2-a]pyridin-2-yl]methoxy]isoindole-1,3-dione;2-(6-methylidene-2-oxopiperidin-3-yl)-4-[[2-(morpholin-4-ylmethyl)imidazo[1,2-a]pyridin-6-yl]methoxy]-3H-isoindol-1-one;2-(6-methylidene-2-oxopiperidin-3-yl)-4-[[5-(morpholin-4-ylmethyl)-1,2-oxazol-3-yl]methoxy]-3H-isoindol-1-one;2-(6-methylidene-2-oxopiperidin-3-yl)-4-[[5-(morpholin-4-ylmethyl)-2-pyridinyl]methoxy]-3H-isoindol-1-one;2-(6-methylidene-2-oxopiperidin-3-yl)-4-[[3-[(4-propan-2-ylpiperidin-1-yl)methyl]-1,2-oxazol-5-yl]methoxy]-3H-isoindol-1-one
• PubChem CID: 159395369
• Molecular Formula: C130H145N21O22
• Molecular Weight: 2353.71 g/mol
• Exact Mass: 2352.09
• IUPAC Name: 2-(4-methylidene-2-oxocyclohexyl)-4-[[6-(morpholin-4-ylmethyl)imidazo[1,2-a]pyridin-2-yl]methoxy]isoindole-1,3-dione;2-(6-methylidene-2-oxopiperidin-3-yl)-4-[[2-(morpholin-4-ylmethyl)imidazo[1,2-a]pyridin-6-yl]methoxy]-3H-isoindol-1-one;2-(6-methylidene-2-oxopiperidin-3-yl)-4-[[5-(morpholin-4-ylmethyl)-1,2-oxazol-3-yl]methoxy]-3H-isoindol-1-one;2-(6-methylidene-2-oxopiperidin-3-yl)-4-[[5-(morpholin-4-ylmethyl)-2-pyridinyl]methoxy]-3H-isoindol-1-one;2-(6-methylidene-2-oxopiperidin-3-yl)-4-[[3-[(4-propan-2-ylpiperidin-1-yl)methyl]-1,2-oxazol-5-yl]methoxy]-3H-isoindol-1-one
• SMILES: C=C1CCC(N2C(=O)c3cccc(OCc4cn5cc(CN6CCOCC6)ccc5n4)c3C2=O)C(=O)C1.C=C1CCC(N2Cc3c(OCc4cc(CN5CCC(C(C)C)CC5)no4)cccc3C2=O)C(=O)N1.C=C1CCC(N2Cc3c(OCc4cc(CN5CCOCC5)on4)cccc3C2=O)C(=O)N1.C=C1CCC(N2Cc3c(OCc4ccc(CN5CCOCC5)cn4)cccc3C2=O)C(=O)N1.C=C1CCC(N2Cc3c(OCc4ccc5nc(CN6CCOCC6)cn5c4)cccc3C2=O)C(=O)N1
• InChI: InChI=1S/C28H28N4O5.C27H29N5O4.C27H34N4O4.C25H28N4O4.C23H26N4O5/c1-18-5-7-22(23(33)13-18)32-27(34)21-3-2-4-24(26(21)28(32)35)37-17-20-16-31-15-19(6-8-25(31)29-20)14-30-9-11-36-12-10-30;1-18-5-7-23(26(33)28-18)32-16-22-21(27(32)34)3-2-4-24(22)36-17-19-6-8-25-29-20(15-31(25)13-19)14-30-9-11-35-12-10-30;1-17(2)19-9-11-30(12-10-19)14-20-13-21(35-29-20)16-34-25-6-4-5-22-23(25)15-31(27(22)33)24-8-7-18(3)28-26(24)32;1-17-5-8-22(24(30)27-17)29-15-21-20(25(29)31)3-2-4-23(21)33-16-19-7-6-18(13-26-19)14-28-9-11-32-12-10-28;1-15-5-6-20(22(28)24-15)27-13-19-18(23(27)29)3-2-4-21(19)31-14-16-11-17(32-25-16)12-26-7-9-30-10-8-26/h2-4,6,8,15-16,22H,1,5,7,9-14,17H2;2-4,6,8,13,15,23H,1,5,7,9-12,14,16-17H2,(H,28,33);4-6,13,17,19,24H,3,7-12,14-16H2,1-2H3,(H,28,32);2-4,6-7,13,22H,1,5,8-12,14-16H2,(H,27,30);2-4,11,20H,1,5-10,12-14H2,(H,24,28)
• InChIKey: LMQJZBHJUMSJFA-UHFFFAOYSA-N
• XLogP: 13.46
• TPSA: 450.91 Ų
• H-Bond Donors: 4
• H-Bond Acceptors: 34
• Rotatable Bonds: 31
• Heavy Atoms: 173
• Complexity: —

Lipinski Rule of Five

3 violations

Rule	Value
MW ≤ 500	2353.71
LogP ≤ 5	13.46
H-Bond Donors ≤ 5	4
H-Bond Acceptors ≤ 10	34

Computed Properties (RDKit)

• Structural Alerts: {'alert_name': 'isolated_alkene', 'substructure': 'N/A'}, {'alert_name': 'phthalimide', 'substructure': 'N/A'}

Frequently Asked Questions

What is the IUPAC name of 2-(4-methylidene-2-oxocyclohexyl)-4-[[6-(morpholin-4-ylmethyl)imidazo[1,2-a]pyridin-2-yl]methoxy]isoindole-1,3-dione;2-(6-methylidene-2-oxopiperidin-3-yl)-4-[[2-(morpholin-4-ylmethyl)imidazo[1,2-a]pyridin-6-yl]methoxy]-3H-isoindol-1-one;2-(6-methylidene-2-oxopiperidin-3-yl)-4-[[5-(morpholin-4-ylmethyl)-1,2-oxazol-3-yl]methoxy]-3H-isoindol-1-one;2-(6-methylidene-2-oxopiperidin-3-yl)-4-[[5-(morpholin-4-ylmethyl)-2-pyridinyl]methoxy]-3H-isoindol-1-one;2-(6-methylidene-2-oxopiperidin-3-yl)-4-[[3-[(4-propan-2-ylpiperidin-1-yl)methyl]-1,2-oxazol-5-yl]methoxy]-3H-isoindol-1-one?

The IUPAC name of 2-(4-methylidene-2-oxocyclohexyl)-4-[[6-(morpholin-4-ylmethyl)imidazo[1,2-a]pyridin-2-yl]methoxy]isoindole-1,3-dione;2-(6-methylidene-2-oxopiperidin-3-yl)-4-[[2-(morpholin-4-ylmethyl)imidazo[1,2-a]pyridin-6-yl]methoxy]-3H-isoindol-1-one;2-(6-methylidene-2-oxopiperidin-3-yl)-4-[[5-(morpholin-4-ylmethyl)-1,2-oxazol-3-yl]methoxy]-3H-isoindol-1-one;2-(6-methylidene-2-oxopiperidin-3-yl)-4-[[5-(morpholin-4-ylmethyl)-2-pyridinyl]methoxy]-3H-isoindol-1-one;2-(6-methylidene-2-oxopiperidin-3-yl)-4-[[3-[(4-propan-2-ylpiperidin-1-yl)methyl]-1,2-oxazol-5-yl]methoxy]-3H-isoindol-1-one (CID 159395369) is 2-(4-methylidene-2-oxocyclohexyl)-4-[[6-(morpholin-4-ylmethyl)imidazo[1,2-a]pyridin-2-yl]methoxy]isoindole-1,3-dione;2-(6-methylidene-2-oxopiperidin-3-yl)-4-[[2-(morpholin-4-ylmethyl)imidazo[1,2-a]pyridin-6-yl]methoxy]-3H-isoindol-1-one;2-(6-methylidene-2-oxopiperidin-3-yl)-4-[[5-(morpholin-4-ylmethyl)-1,2-oxazol-3-yl]methoxy]-3H-isoindol-1-one;2-(6-methylidene-2-oxopiperidin-3-yl)-4-[[5-(morpholin-4-ylmethyl)-2-pyridinyl]methoxy]-3H-isoindol-1-one;2-(6-methylidene-2-oxopiperidin-3-yl)-4-[[3-[(4-propan-2-ylpiperidin-1-yl)methyl]-1,2-oxazol-5-yl]methoxy]-3H-isoindol-1-one.

What is the SMILES notation for 2-(4-methylidene-2-oxocyclohexyl)-4-[[6-(morpholin-4-ylmethyl)imidazo[1,2-a]pyridin-2-yl]methoxy]isoindole-1,3-dione;2-(6-methylidene-2-oxopiperidin-3-yl)-4-[[2-(morpholin-4-ylmethyl)imidazo[1,2-a]pyridin-6-yl]methoxy]-3H-isoindol-1-one;2-(6-methylidene-2-oxopiperidin-3-yl)-4-[[5-(morpholin-4-ylmethyl)-1,2-oxazol-3-yl]methoxy]-3H-isoindol-1-one;2-(6-methylidene-2-oxopiperidin-3-yl)-4-[[5-(morpholin-4-ylmethyl)-2-pyridinyl]methoxy]-3H-isoindol-1-one;2-(6-methylidene-2-oxopiperidin-3-yl)-4-[[3-[(4-propan-2-ylpiperidin-1-yl)methyl]-1,2-oxazol-5-yl]methoxy]-3H-isoindol-1-one?

The canonical SMILES for 2-(4-methylidene-2-oxocyclohexyl)-4-[[6-(morpholin-4-ylmethyl)imidazo[1,2-a]pyridin-2-yl]methoxy]isoindole-1,3-dione;2-(6-methylidene-2-oxopiperidin-3-yl)-4-[[2-(morpholin-4-ylmethyl)imidazo[1,2-a]pyridin-6-yl]methoxy]-3H-isoindol-1-one;2-(6-methylidene-2-oxopiperidin-3-yl)-4-[[5-(morpholin-4-ylmethyl)-1,2-oxazol-3-yl]methoxy]-3H-isoindol-1-one;2-(6-methylidene-2-oxopiperidin-3-yl)-4-[[5-(morpholin-4-ylmethyl)-2-pyridinyl]methoxy]-3H-isoindol-1-one;2-(6-methylidene-2-oxopiperidin-3-yl)-4-[[3-[(4-propan-2-ylpiperidin-1-yl)methyl]-1,2-oxazol-5-yl]methoxy]-3H-isoindol-1-one is C=C1CCC(N2C(=O)c3cccc(OCc4cn5cc(CN6CCOCC6)ccc5n4)c3C2=O)C(=O)C1.C=C1CCC(N2Cc3c(OCc4cc(CN5CCC(C(C)C)CC5)no4)cccc3C2=O)C(=O)N1.C=C1CCC(N2Cc3c(OCc4cc(CN5CCOCC5)on4)cccc3C2=O)C(=O)N1.C=C1CCC(N2Cc3c(OCc4ccc(CN5CCOCC5)cn4)cccc3C2=O)C(=O)N1.C=C1CCC(N2Cc3c(OCc4ccc5nc(CN6CCOCC6)cn5c4)cccc3C2=O)C(=O)N1.

What is the InChIKey of 2-(4-methylidene-2-oxocyclohexyl)-4-[[6-(morpholin-4-ylmethyl)imidazo[1,2-a]pyridin-2-yl]methoxy]isoindole-1,3-dione;2-(6-methylidene-2-oxopiperidin-3-yl)-4-[[2-(morpholin-4-ylmethyl)imidazo[1,2-a]pyridin-6-yl]methoxy]-3H-isoindol-1-one;2-(6-methylidene-2-oxopiperidin-3-yl)-4-[[5-(morpholin-4-ylmethyl)-1,2-oxazol-3-yl]methoxy]-3H-isoindol-1-one;2-(6-methylidene-2-oxopiperidin-3-yl)-4-[[5-(morpholin-4-ylmethyl)-2-pyridinyl]methoxy]-3H-isoindol-1-one;2-(6-methylidene-2-oxopiperidin-3-yl)-4-[[3-[(4-propan-2-ylpiperidin-1-yl)methyl]-1,2-oxazol-5-yl]methoxy]-3H-isoindol-1-one?

The InChIKey is LMQJZBHJUMSJFA-UHFFFAOYSA-N. The full InChI is InChI=1S/C28H28N4O5.C27H29N5O4.C27H34N4O4.C25H28N4O4.C23H26N4O5/c1-18-5-7-22(23(33)13-18)32-27(34)21-3-2-4-24(26(21)28(32)35)37-17-20-16-31-15-19(6-8-25(31)29-20)14-30-9-11-36-12-10-30;1-18-5-7-23(26(33)28-18)32-16-22-21(27(32)34)3-2-4-24(22)36-17-19-6-8-25-29-20(15-31(25)13-19)14-30-9-11-35-12-10-30;1-17(2)19-9-11-30(12-10-19)14-20-13-21(35-29-20)16-34-25-6-4-5-22-23(25)15-31(27(22)33)24-8-7-18(3)28-26(24)32;1-17-5-8-22(24(30)27-17)29-15-21-20(25(29)31)3-2-4-23(21)33-16-19-7-6-18(13-26-19)14-28-9-11-32-12-10-28;1-15-5-6-20(22(28)24-15)27-13-19-18(23(27)29)3-2-4-21(19)31-14-16-11-17(32-25-16)12-26-7-9-30-10-8-26/h2-4,6,8,15-16,22H,1,5,7,9-14,17H2;2-4,6,8,13,15,23H,1,5,7,9-12,14,16-17H2,(H,28,33);4-6,13,17,19,24H,3,7-12,14-16H2,1-2H3,(H,28,32);2-4,6-7,13,22H,1,5,8-12,14-16H2,(H,27,30);2-4,11,20H,1,5-10,12-14H2,(H,24,28).

What are the key properties of 2-(4-methylidene-2-oxocyclohexyl)-4-[[6-(morpholin-4-ylmethyl)imidazo[1,2-a]pyridin-2-yl]methoxy]isoindole-1,3-dione;2-(6-methylidene-2-oxopiperidin-3-yl)-4-[[2-(morpholin-4-ylmethyl)imidazo[1,2-a]pyridin-6-yl]methoxy]-3H-isoindol-1-one;2-(6-methylidene-2-oxopiperidin-3-yl)-4-[[5-(morpholin-4-ylmethyl)-1,2-oxazol-3-yl]methoxy]-3H-isoindol-1-one;2-(6-methylidene-2-oxopiperidin-3-yl)-4-[[5-(morpholin-4-ylmethyl)-2-pyridinyl]methoxy]-3H-isoindol-1-one;2-(6-methylidene-2-oxopiperidin-3-yl)-4-[[3-[(4-propan-2-ylpiperidin-1-yl)methyl]-1,2-oxazol-5-yl]methoxy]-3H-isoindol-1-one?

2-(4-methylidene-2-oxocyclohexyl)-4-[[6-(morpholin-4-ylmethyl)imidazo[1,2-a]pyridin-2-yl]methoxy]isoindole-1,3-dione;2-(6-methylidene-2-oxopiperidin-3-yl)-4-[[2-(morpholin-4-ylmethyl)imidazo[1,2-a]pyridin-6-yl]methoxy]-3H-isoindol-1-one;2-(6-methylidene-2-oxopiperidin-3-yl)-4-[[5-(morpholin-4-ylmethyl)-1,2-oxazol-3-yl]methoxy]-3H-isoindol-1-one;2-(6-methylidene-2-oxopiperidin-3-yl)-4-[[5-(morpholin-4-ylmethyl)-2-pyridinyl]methoxy]-3H-isoindol-1-one;2-(6-methylidene-2-oxopiperidin-3-yl)-4-[[3-[(4-propan-2-ylpiperidin-1-yl)methyl]-1,2-oxazol-5-yl]methoxy]-3H-isoindol-1-one has a molecular weight of 2353.71 g/mol, XLogP of 13.46, 31 rotatable bonds, 4 hydrogen bond donors, and 34 hydrogen bond acceptors.

Where does this data come from?

All data for 2-(4-methylidene-2-oxocyclohexyl)-4-[[6-(morpholin-4-ylmethyl)imidazo[1,2-a]pyridin-2-yl]methoxy]isoindole-1,3-dione;2-(6-methylidene-2-oxopiperidin-3-yl)-4-[[2-(morpholin-4-ylmethyl)imidazo[1,2-a]pyridin-6-yl]methoxy]-3H-isoindol-1-one;2-(6-methylidene-2-oxopiperidin-3-yl)-4-[[5-(morpholin-4-ylmethyl)-1,2-oxazol-3-yl]methoxy]-3H-isoindol-1-one;2-(6-methylidene-2-oxopiperidin-3-yl)-4-[[5-(morpholin-4-ylmethyl)-2-pyridinyl]methoxy]-3H-isoindol-1-one;2-(6-methylidene-2-oxopiperidin-3-yl)-4-[[3-[(4-propan-2-ylpiperidin-1-yl)methyl]-1,2-oxazol-5-yl]methoxy]-3H-isoindol-1-one is sourced from PubChem (CID 159395369), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).