N-[6-amino-5-[1-methyl-3-(trifluoromethyl)pyrazol-5-yl]-2-pyridinyl]-2-cyclohexylacetamide;N-[6-amino-5-[1-methyl-3-(trifluoromethyl)pyrazol-5-yl]-2-pyridinyl]-3-cyclopentylpropanamide;N-[6-amino-5-[1-methyl-3-(trifluoromethyl)pyrazol-5-yl]-2-pyridinyl]-3-phenylpropanamide;(E)-N-[6-amino-5-[1-methyl-3-(trifluoromethyl)pyrazol-5-yl]-2-pyridinyl]-3-phenylprop-2-enamide;N-[5-[1-ethyl-3-(trifluoromethyl)pyrazol-5-yl]-6-fluoro-2-pyridinyl]-3-methylbenzamide;N-[6-fluoro-5-(1-methylindol-2-yl)-2-pyridinyl]-3-methylbenzamide;N-[6-fluoro-5-(1-methylindol-2-yl)-2-pyridinyl]-4-methylbenzamide

C137H130F18N30O7 — CID 159409155

IUPACN-[6-amino-5-[1-methyl-3-(trifluoromethyl)pyrazol-5-yl]-2-pyridinyl]-2-cyclohexylacetamide;N-[6-amino-5-[1-methyl-3-(trifluoromethyl)pyrazol-5-yl]-2-pyridinyl]-3-cyclopentylpropanamide;N-[6-amino-5-[1-methyl-3-(trifluoromethyl)pyrazol-5-yl]-2-pyridinyl]-3-phenylpropanamide;(E)-N-[6-amino-5-[1-methyl-3-(trifluoromethyl)pyrazol-5-yl]-2-pyridinyl]-3-phenylprop-2-enamide;N-[5-[1-ethyl-3-(trifluoromethyl)pyrazol-5-yl]-6-fluoro-2-pyridinyl]-3-methylbenzamide;N-[6-fluoro-5-(1-methylindol-2-yl)-2-pyridinyl]-3-methylbenzamide;N-[6-fluoro-5-(1-methylindol-2-yl)-2-pyridinyl]-4-methylbenzamide
SMILESCCn1nc(C(F)(F)F)cc1-c1ccc(NC(=O)c2cccc(C)c2)nc1F.Cc1ccc(C(=O)Nc2ccc(-c3cc4ccccc4n3C)c(F)n2)cc1.Cc1cccc(C(=O)Nc2ccc(-c3cc4ccccc4n3C)c(F)n2)c1.Cn1nc(C(F)(F)F)cc1-c1ccc(NC(=O)/C=C/c2ccccc2)nc1N.Cn1nc(C(F)(F)F)cc1-c1ccc(NC(=O)CC2CCCCC2)nc1N.Cn1nc(C(F)(F)F)cc1-c1ccc(NC(=O)CCC2CCCC2)nc1N.Cn1nc(C(F)(F)F)cc1-c1ccc(NC(=O)CCc2ccccc2)nc1N
InChIInChI=1S/2C22H18FN3O.C19H16F4N4O.C19H18F3N5O.C19H16F3N5O.2C18H22F3N5O/c1-14-6-5-8-16(12-14)22(27)25-20-11-10-17(21(23)24-20)19-13-15-7-3-4-9-18(15)26(19)2;1-14-7-9-15(10-8-14)22(27)25-20-12-11-17(21(23)24-20)19-13-16-5-3-4-6-18(16)26(19)2;1-3-27-14(10-15(26-27)19(21,22)23)13-7-8-16(24-17(13)20)25-18(28)12-6-4-5-11(2)9-12;2*1-27-14(11-15(26-27)19(20,21)22)13-8-9-16(25-18(13)23)24-17(28)10-7-12-5-3-2-4-6-12;1-26-13(10-14(25-26)18(19,20)21)12-7-8-15(24-17(12)22)23-16(27)9-6-11-4-2-3-5-11;1-26-13(10-14(25-26)18(19,20)21)12-7-8-15(24-17(12)22)23-16(27)9-11-5-3-2-4-6-11/h2*3-13H,1-2H3,(H,24,25,27);4-10H,3H2,1-2H3,(H,24,25,28);2-6,8-9,11H,7,10H2,1H3,(H3,23,24,25,28);2-11H,1H3,(H3,23,24,25,28);2*7-8,10-11H,2-6,9H2,1H3,(H3,22,23,24,27)/b;;;;10-7+;;
InChIKeyLOIUVJAZNAEWJY-INCBJQFRSA-N
MW2650.71 g/mol
LogP29.94
Rot. Bonds28

About N-[6-amino-5-[1-methyl-3-(trifluoromethyl)pyrazol-5-yl]-2-pyridinyl]-2-cyclohexylacetamide;N-[6-amino-5-[1-methyl-3-(trifluoromethyl)pyrazol-5-yl]-2-pyridinyl]-3-cyclopentylpropanamide;N-[6-amino-5-[1-methyl-3-(trifluoromethyl)pyrazol-5-yl]-2-pyridinyl]-3-phenylpropanamide;(E)-N-[6-amino-5-[1-methyl-3-(trifluoromethyl)pyrazol-5-yl]-2-pyridinyl]-3-phenylprop-2-enamide;N-[5-[1-ethyl-3-(trifluoromethyl)pyrazol-5-yl]-6-fluoro-2-pyridinyl]-3-methylbenzamide;N-[6-fluoro-5-(1-methylindol-2-yl)-2-pyridinyl]-3-methylbenzamide;N-[6-fluoro-5-(1-methylindol-2-yl)-2-pyridinyl]-4-methylbenzamide

N-[6-amino-5-[1-methyl-3-(trifluoromethyl)pyrazol-5-yl]-2-pyridinyl]-2-cyclohexylacetamide;N-[6-amino-5-[1-methyl-3-(trifluoromethyl)pyrazol-5-yl]-2-pyridinyl]-3-cyclopentylpropanamide;N-[6-amino-5-[1-methyl-3-(trifluoromethyl)pyrazol-5-yl]-2-pyridinyl]-3-phenylpropanamide;(E)-N-[6-amino-5-[1-methyl-3-(trifluoromethyl)pyrazol-5-yl]-2-pyridinyl]-3-phenylprop-2-enamide;N-[5-[1-ethyl-3-(trifluoromethyl)pyrazol-5-yl]-6-fluoro-2-pyridinyl]-3-methylbenzamide;N-[6-fluoro-5-(1-methylindol-2-yl)-2-pyridinyl]-3-methylbenzamide;N-[6-fluoro-5-(1-methylindol-2-yl)-2-pyridinyl]-4-methylbenzamide (PubChem CID 159409155) has the molecular formula C137H130F18N30O7 and a molecular weight of 2650.71 g/mol. Its IUPAC name is N-[6-amino-5-[1-methyl-3-(trifluoromethyl)pyrazol-5-yl]-2-pyridinyl]-2-cyclohexylacetamide;N-[6-amino-5-[1-methyl-3-(trifluoromethyl)pyrazol-5-yl]-2-pyridinyl]-3-cyclopentylpropanamide;N-[6-amino-5-[1-methyl-3-(trifluoromethyl)pyrazol-5-yl]-2-pyridinyl]-3-phenylpropanamide;(E)-N-[6-amino-5-[1-methyl-3-(trifluoromethyl)pyrazol-5-yl]-2-pyridinyl]-3-phenylprop-2-enamide;N-[5-[1-ethyl-3-(trifluoromethyl)pyrazol-5-yl]-6-fluoro-2-pyridinyl]-3-methylbenzamide;N-[6-fluoro-5-(1-methylindol-2-yl)-2-pyridinyl]-3-methylbenzamide;N-[6-fluoro-5-(1-methylindol-2-yl)-2-pyridinyl]-4-methylbenzamide.

Molecular Properties

Compound NameN-[6-amino-5-[1-methyl-3-(trifluoromethyl)pyrazol-5-yl]-2-pyridinyl]-2-cyclohexylacetamide;N-[6-amino-5-[1-methyl-3-(trifluoromethyl)pyrazol-5-yl]-2-pyridinyl]-3-cyclopentylpropanamide;N-[6-amino-5-[1-methyl-3-(trifluoromethyl)pyrazol-5-yl]-2-pyridinyl]-3-phenylpropanamide;(E)-N-[6-amino-5-[1-methyl-3-(trifluoromethyl)pyrazol-5-yl]-2-pyridinyl]-3-phenylprop-2-enamide;N-[5-[1-ethyl-3-(trifluoromethyl)pyrazol-5-yl]-6-fluoro-2-pyridinyl]-3-methylbenzamide;N-[6-fluoro-5-(1-methylindol-2-yl)-2-pyridinyl]-3-methylbenzamide;N-[6-fluoro-5-(1-methylindol-2-yl)-2-pyridinyl]-4-methylbenzamide
PubChem CID159409155
Molecular FormulaC137H130F18N30O7
Molecular Weight2650.71 g/mol
Exact Mass2649.05
IUPAC NameN-[6-amino-5-[1-methyl-3-(trifluoromethyl)pyrazol-5-yl]-2-pyridinyl]-2-cyclohexylacetamide;N-[6-amino-5-[1-methyl-3-(trifluoromethyl)pyrazol-5-yl]-2-pyridinyl]-3-cyclopentylpropanamide;N-[6-amino-5-[1-methyl-3-(trifluoromethyl)pyrazol-5-yl]-2-pyridinyl]-3-phenylpropanamide;(E)-N-[6-amino-5-[1-methyl-3-(trifluoromethyl)pyrazol-5-yl]-2-pyridinyl]-3-phenylprop-2-enamide;N-[5-[1-ethyl-3-(trifluoromethyl)pyrazol-5-yl]-6-fluoro-2-pyridinyl]-3-methylbenzamide;N-[6-fluoro-5-(1-methylindol-2-yl)-2-pyridinyl]-3-methylbenzamide;N-[6-fluoro-5-(1-methylindol-2-yl)-2-pyridinyl]-4-methylbenzamide
SMILESCCn1nc(C(F)(F)F)cc1-c1ccc(NC(=O)c2cccc(C)c2)nc1F.Cc1ccc(C(=O)Nc2ccc(-c3cc4ccccc4n3C)c(F)n2)cc1.Cc1cccc(C(=O)Nc2ccc(-c3cc4ccccc4n3C)c(F)n2)c1.Cn1nc(C(F)(F)F)cc1-c1ccc(NC(=O)/C=C/c2ccccc2)nc1N.Cn1nc(C(F)(F)F)cc1-c1ccc(NC(=O)CC2CCCCC2)nc1N.Cn1nc(C(F)(F)F)cc1-c1ccc(NC(=O)CCC2CCCC2)nc1N.Cn1nc(C(F)(F)F)cc1-c1ccc(NC(=O)CCc2ccccc2)nc1N
InChIInChI=1S/2C22H18FN3O.C19H16F4N4O.C19H18F3N5O.C19H16F3N5O.2C18H22F3N5O/c1-14-6-5-8-16(12-14)22(27)25-20-11-10-17(21(23)24-20)19-13-15-7-3-4-9-18(15)26(19)2;1-14-7-9-15(10-8-14)22(27)25-20-12-11-17(21(23)24-20)19-13-16-5-3-4-6-18(16)26(19)2;1-3-27-14(10-15(26-27)19(21,22)23)13-7-8-16(24-17(13)20)25-18(28)12-6-4-5-11(2)9-12;2*1-27-14(11-15(26-27)19(20,21)22)13-8-9-16(25-18(13)23)24-17(28)10-7-12-5-3-2-4-6-12;1-26-13(10-14(25-26)18(19,20)21)12-7-8-15(24-17(12)22)23-16(27)9-6-11-4-2-3-5-11;1-26-13(10-14(25-26)18(19,20)21)12-7-8-15(24-17(12)22)23-16(27)9-11-5-3-2-4-6-11/h2*3-13H,1-2H3,(H,24,25,27);4-10H,3H2,1-2H3,(H,24,25,28);2-6,8-9,11H,7,10H2,1H3,(H3,23,24,25,28);2-11H,1H3,(H3,23,24,25,28);2*7-8,10-11H,2-6,9H2,1H3,(H3,22,23,24,27)/b;;;;10-7+;;
InChIKeyLOIUVJAZNAEWJY-INCBJQFRSA-N
XLogP29.94
TPSA496.97 Ų
H-Bond Donors11
H-Bond Acceptors30
Rotatable Bonds28
Heavy Atoms192
Complexity—

Lipinski Rule of Five

4 violations

RuleValue
MW ≤ 5002650.71
LogP ≤ 529.94
H-Bond Donors ≤ 511
H-Bond Acceptors ≤ 1030

Computed Properties (RDKit)

Structural Alerts{'alert_name': '2-halo_pyridine', 'substructure': 'N/A'}, {'alert_name': 'Michael_acceptor_1', 'substructure': 'N/A'}

Analyze N-[6-amino-5-[1-methyl-3-(trifluoromethyl)pyrazol-5-yl]-2-pyridinyl]-2-cyclohexylacetamide;N-[6-amino-5-[1-methyl-3-(trifluoromethyl)pyrazol-5-yl]-2-pyridinyl]-3-cyclopentylpropanamide;N-[6-amino-5-[1-methyl-3-(trifluoromethyl)pyrazol-5-yl]-2-pyridinyl]-3-phenylpropanamide;(E)-N-[6-amino-5-[1-methyl-3-(trifluoromethyl)pyrazol-5-yl]-2-pyridinyl]-3-phenylprop-2-enamide;N-[5-[1-ethyl-3-(trifluoromethyl)pyrazol-5-yl]-6-fluoro-2-pyridinyl]-3-methylbenzamide;N-[6-fluoro-5-(1-methylindol-2-yl)-2-pyridinyl]-3-methylbenzamide;N-[6-fluoro-5-(1-methylindol-2-yl)-2-pyridinyl]-4-methylbenzamide with MolForge

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Related Compounds

5-[5-[(4,4-difluoropiperidin-1-yl)methyl]-3-pyridinyl]-N-(6-pyrrolidin-1-yl-3-pyridinyl)-1-[1-[5-[[5-(5-pyrrolidin-1-yl-3-pyridinyl)-1H-indazole-3-carbonyl]amino]-2-pyridinyl]pyrrolidin-3-yl]indazole-3-carboxamide
CID 146233157
5-[5-[(4,4-difluoropiperidin-1-yl)methyl]-3-pyridinyl]-N-[6-(4-methylpiperidin-1-yl)-3-pyridinyl]-1H-indazole-3-carboxamide;5-[5-[(3,3-difluoropyrrolidin-1-yl)methyl]-3-pyridinyl]-N-[6-(4-methylpiperidin-1-yl)-3-pyridinyl]-1H-indazole-3-carboxamide;N-[6-(4-methylpiperidin-1-yl)-3-pyridinyl]-5-(5-pyrrolidin-1-yl-3-pyridinyl)-1H-indazole-3-carboxamide
CID 157052033
N-[6-amino-5-[1-methyl-3-(trifluoromethyl)pyrazol-5-yl]-2-pyridinyl]-2-cyclohexylacetamide;N-[6-amino-5-[1-methyl-3-(trifluoromethyl)pyrazol-5-yl]-2-pyridinyl]-3-cyclopentylpropanamide;(E)-N-[6-amino-5-[1-methyl-3-(trifluoromethyl)pyrazol-5-yl]-2-pyridinyl]-3-phenylprop-2-enamide;2-chloro-N-[5-[1-ethyl-3-(trifluoromethyl)pyrazol-5-yl]-6-fluoro-2-pyridinyl]benzamide;N-[5-[1-ethyl-3-(trifluoromethyl)pyrazol-5-yl]-6-fluoro-2-pyridinyl]-3-methylbenzamide;N-[6-fluoro-5-(1-methylindol-2-yl)-2-pyridinyl]-3-methylbenzamide;N-[6-fluoro-5-(1-methylindol-2-yl)-2-pyridinyl]-4-methylbenzamide
CID 157104187
N-benzyl-6-[3-pyridin-3-yl-5-(trifluoromethyl)pyrazol-1-yl]pyridine-3-carboxamide;N-cyclohexyl-6-[3-pyridin-3-yl-5-(trifluoromethyl)pyrazol-1-yl]pyridine-3-carboxamide;N-(3,3-diphenylpropyl)-6-[3-pyridin-3-yl-5-(trifluoromethyl)pyrazol-1-yl]pyridine-3-carboxamide;N-hexyl-6-[3-pyridin-3-yl-5-(trifluoromethyl)pyrazol-1-yl]pyridine-3-carboxamide;N-(2-phenylethyl)-4-[5-pyridin-3-yl-3-(trifluoromethyl)pyrazol-1-yl]benzamide;N-(3-phenylpropyl)-4-[5-pyridin-3-yl-3-(trifluoromethyl)pyrazol-1-yl]benzamide
CID 157141744
N-[6-amino-5-[1-ethyl-3-(trifluoromethyl)pyrazol-5-yl]-2-pyridinyl]benzamide;N-[6-amino-5-[1-ethyl-3-(trifluoromethyl)pyrazol-5-yl]-2-pyridinyl]-4-methylbenzamide;N-[6-amino-3-fluoro-5-[1-methyl-3-(trifluoromethyl)pyrazol-5-yl]-2-pyridinyl]-4-methylbenzamide;N-[6-amino-5-(4-methylnaphthalen-1-yl)-2-pyridinyl]-4-methylbenzamide;N-[6-amino-5-[1-propan-2-yl-3-(trifluoromethyl)pyrazol-5-yl]-2-pyridinyl]benzamide;N-[6-amino-5-[1-propan-2-yl-3-(trifluoromethyl)pyrazol-5-yl]-2-pyridinyl]-4-methylbenzamide
CID 157224718
N-[5-(1,3-diethylpyrazol-5-yl)-6-fluoro-2-pyridinyl]-2,6-difluorobenzamide;N-[5-(1,3-diethylpyrazol-5-yl)-6-fluoro-2-pyridinyl]-2-fluorobenzamide;2,6-difluoro-N-[6-fluoro-5-(1-methylindol-2-yl)-2-pyridinyl]benzamide;N-[5-[1-ethyl-3-(trifluoromethyl)pyrazol-5-yl]-6-fluoro-2-pyridinyl]-2,6-difluorobenzamide;N-[5-[1-ethyl-3-(trifluoromethyl)pyrazol-5-yl]-6-fluoro-2-pyridinyl]-2-fluorobenzamide;N-[5-[1-ethyl-3-(trifluoromethyl)pyrazol-5-yl]-6-fluoro-2-pyridinyl]-4-methylbenzamide
CID 157331920
5-[3,3-dimethyl-1-(1-methylpyrazol-4-yl)-2-oxoindol-4-yl]-N-(4-methylphenyl)-2-(trifluoromethyl)benzamide;3-(3,3-dimethyl-2-oxo-1-pyrimidin-2-ylindol-4-yl)-2-fluoro-6-methyl-N-(4-methylphenyl)benzamide;5-(3,3-dimethyl-2-oxo-1-pyrimidin-2-ylindol-4-yl)-2-methyl-N-(4-methylphenyl)pyridine-3-carboxamide;5-[1-(5-fluoro-3-pyridinyl)-3,3-dimethyl-2-oxoindol-4-yl]-N-(4-methylphenyl)-2-(trifluoromethyl)pyridine-3-carboxamide
CID 157356270
N-[4-(cyclopropanecarbonylamino)-3-pyridinyl]-5-pyridin-3-yl-1H-indazole-3-carboxamide;5-[5-[(3,3-difluoropyrrolidin-1-yl)methyl]-3-pyridinyl]-N-phenyl-1H-indazole-3-carboxamide;N-[3-(3-fluorophenyl)phenyl]-5-pyridin-3-yl-1H-indazole-3-carboxamide;N-[4-(4-methylpiperazin-1-yl)-3-pyridinyl]-5-pyridin-3-yl-1H-indazole-3-carboxamide;N-[6-(4-methylpiperazin-1-yl)-3-pyridinyl]-5-pyridin-3-yl-1H-indazole-3-carboxamide
CID 157356698
2-methyl-N-(4-methylphenyl)-5-[3-(1H-pyrazol-5-yl)imidazo[1,5-a]pyridin-8-yl]benzamide;bis(N-(4-methylphenyl)-5-(3-pyridin-2-ylimidazo[1,5-a]pyridin-8-yl)-2-(trifluoromethyl)benzamide);N-(4-methylphenyl)-5-(3-pyrimidin-4-ylimidazo[1,5-a]pyridin-8-yl)-2-(trifluoromethyl)benzamide
CID 157377466
5-[5-[(4,4-difluoropiperidin-1-yl)methyl]-3-pyridinyl]-N-(6-piperidin-1-yl-3-pyridinyl)-1H-indazole-3-carboxamide;5-[5-[(3,3-difluoropyrrolidin-1-yl)methyl]-3-pyridinyl]-N-(6-piperidin-1-yl-3-pyridinyl)-1H-indazole-3-carboxamide;5-(5-piperidin-1-yl-3-pyridinyl)-N-(6-piperidin-1-yl-3-pyridinyl)-1H-indazole-3-carboxamide;N-(6-piperidin-1-yl-3-pyridinyl)-5-(5-pyrrolidin-1-yl-3-pyridinyl)-1H-indazole-3-carboxamide
CID 157441604
5-[5-[(4,4-difluoropiperidin-1-yl)methyl]-3-pyridinyl]-N-(6-piperidin-1-yl-3-pyridinyl)-1H-indazole-3-carboxamide;5-[5-[(3,3-difluoropyrrolidin-1-yl)methyl]-3-pyridinyl]-N-(6-piperidin-1-yl-3-pyridinyl)-1H-indazole-3-carboxamide;methane;5-(5-piperidin-1-yl-3-pyridinyl)-N-(6-piperidin-1-yl-3-pyridinyl)-1H-indazole-3-carboxamide;N-(6-piperidin-1-yl-3-pyridinyl)-5-(5-pyrrolidin-1-yl-3-pyridinyl)-1H-indazole-3-carboxamide
CID 157478101
5-[3,3-dimethyl-1-(1-methylpyrazol-3-yl)-2-oxoindol-4-yl]-N-(4-methylphenyl)-2-(trifluoromethyl)benzamide;5-(3,3-dimethyl-2-oxo-1-pyridin-2-ylpyrrolo[2,3-b]pyridin-4-yl)-N-(4-methylphenyl)-2-(trifluoromethyl)benzamide;5-(3,3-dimethyl-2-oxo-1-pyrimidin-2-ylindol-4-yl)-N-phenyl-2-(trifluoromethyl)benzamide
CID 157505413

Frequently Asked Questions

What is the IUPAC name of N-[6-amino-5-[1-methyl-3-(trifluoromethyl)pyrazol-5-yl]-2-pyridinyl]-2-cyclohexylacetamide;N-[6-amino-5-[1-methyl-3-(trifluoromethyl)pyrazol-5-yl]-2-pyridinyl]-3-cyclopentylpropanamide;N-[6-amino-5-[1-methyl-3-(trifluoromethyl)pyrazol-5-yl]-2-pyridinyl]-3-phenylpropanamide;(E)-N-[6-amino-5-[1-methyl-3-(trifluoromethyl)pyrazol-5-yl]-2-pyridinyl]-3-phenylprop-2-enamide;N-[5-[1-ethyl-3-(trifluoromethyl)pyrazol-5-yl]-6-fluoro-2-pyridinyl]-3-methylbenzamide;N-[6-fluoro-5-(1-methylindol-2-yl)-2-pyridinyl]-3-methylbenzamide;N-[6-fluoro-5-(1-methylindol-2-yl)-2-pyridinyl]-4-methylbenzamide?
The IUPAC name of N-[6-amino-5-[1-methyl-3-(trifluoromethyl)pyrazol-5-yl]-2-pyridinyl]-2-cyclohexylacetamide;N-[6-amino-5-[1-methyl-3-(trifluoromethyl)pyrazol-5-yl]-2-pyridinyl]-3-cyclopentylpropanamide;N-[6-amino-5-[1-methyl-3-(trifluoromethyl)pyrazol-5-yl]-2-pyridinyl]-3-phenylpropanamide;(E)-N-[6-amino-5-[1-methyl-3-(trifluoromethyl)pyrazol-5-yl]-2-pyridinyl]-3-phenylprop-2-enamide;N-[5-[1-ethyl-3-(trifluoromethyl)pyrazol-5-yl]-6-fluoro-2-pyridinyl]-3-methylbenzamide;N-[6-fluoro-5-(1-methylindol-2-yl)-2-pyridinyl]-3-methylbenzamide;N-[6-fluoro-5-(1-methylindol-2-yl)-2-pyridinyl]-4-methylbenzamide (CID 159409155) is N-[6-amino-5-[1-methyl-3-(trifluoromethyl)pyrazol-5-yl]-2-pyridinyl]-2-cyclohexylacetamide;N-[6-amino-5-[1-methyl-3-(trifluoromethyl)pyrazol-5-yl]-2-pyridinyl]-3-cyclopentylpropanamide;N-[6-amino-5-[1-methyl-3-(trifluoromethyl)pyrazol-5-yl]-2-pyridinyl]-3-phenylpropanamide;(E)-N-[6-amino-5-[1-methyl-3-(trifluoromethyl)pyrazol-5-yl]-2-pyridinyl]-3-phenylprop-2-enamide;N-[5-[1-ethyl-3-(trifluoromethyl)pyrazol-5-yl]-6-fluoro-2-pyridinyl]-3-methylbenzamide;N-[6-fluoro-5-(1-methylindol-2-yl)-2-pyridinyl]-3-methylbenzamide;N-[6-fluoro-5-(1-methylindol-2-yl)-2-pyridinyl]-4-methylbenzamide.
What is the SMILES notation for N-[6-amino-5-[1-methyl-3-(trifluoromethyl)pyrazol-5-yl]-2-pyridinyl]-2-cyclohexylacetamide;N-[6-amino-5-[1-methyl-3-(trifluoromethyl)pyrazol-5-yl]-2-pyridinyl]-3-cyclopentylpropanamide;N-[6-amino-5-[1-methyl-3-(trifluoromethyl)pyrazol-5-yl]-2-pyridinyl]-3-phenylpropanamide;(E)-N-[6-amino-5-[1-methyl-3-(trifluoromethyl)pyrazol-5-yl]-2-pyridinyl]-3-phenylprop-2-enamide;N-[5-[1-ethyl-3-(trifluoromethyl)pyrazol-5-yl]-6-fluoro-2-pyridinyl]-3-methylbenzamide;N-[6-fluoro-5-(1-methylindol-2-yl)-2-pyridinyl]-3-methylbenzamide;N-[6-fluoro-5-(1-methylindol-2-yl)-2-pyridinyl]-4-methylbenzamide?
The canonical SMILES for N-[6-amino-5-[1-methyl-3-(trifluoromethyl)pyrazol-5-yl]-2-pyridinyl]-2-cyclohexylacetamide;N-[6-amino-5-[1-methyl-3-(trifluoromethyl)pyrazol-5-yl]-2-pyridinyl]-3-cyclopentylpropanamide;N-[6-amino-5-[1-methyl-3-(trifluoromethyl)pyrazol-5-yl]-2-pyridinyl]-3-phenylpropanamide;(E)-N-[6-amino-5-[1-methyl-3-(trifluoromethyl)pyrazol-5-yl]-2-pyridinyl]-3-phenylprop-2-enamide;N-[5-[1-ethyl-3-(trifluoromethyl)pyrazol-5-yl]-6-fluoro-2-pyridinyl]-3-methylbenzamide;N-[6-fluoro-5-(1-methylindol-2-yl)-2-pyridinyl]-3-methylbenzamide;N-[6-fluoro-5-(1-methylindol-2-yl)-2-pyridinyl]-4-methylbenzamide is CCn1nc(C(F)(F)F)cc1-c1ccc(NC(=O)c2cccc(C)c2)nc1F.Cc1ccc(C(=O)Nc2ccc(-c3cc4ccccc4n3C)c(F)n2)cc1.Cc1cccc(C(=O)Nc2ccc(-c3cc4ccccc4n3C)c(F)n2)c1.Cn1nc(C(F)(F)F)cc1-c1ccc(NC(=O)/C=C/c2ccccc2)nc1N.Cn1nc(C(F)(F)F)cc1-c1ccc(NC(=O)CC2CCCCC2)nc1N.Cn1nc(C(F)(F)F)cc1-c1ccc(NC(=O)CCC2CCCC2)nc1N.Cn1nc(C(F)(F)F)cc1-c1ccc(NC(=O)CCc2ccccc2)nc1N.
What is the InChIKey of N-[6-amino-5-[1-methyl-3-(trifluoromethyl)pyrazol-5-yl]-2-pyridinyl]-2-cyclohexylacetamide;N-[6-amino-5-[1-methyl-3-(trifluoromethyl)pyrazol-5-yl]-2-pyridinyl]-3-cyclopentylpropanamide;N-[6-amino-5-[1-methyl-3-(trifluoromethyl)pyrazol-5-yl]-2-pyridinyl]-3-phenylpropanamide;(E)-N-[6-amino-5-[1-methyl-3-(trifluoromethyl)pyrazol-5-yl]-2-pyridinyl]-3-phenylprop-2-enamide;N-[5-[1-ethyl-3-(trifluoromethyl)pyrazol-5-yl]-6-fluoro-2-pyridinyl]-3-methylbenzamide;N-[6-fluoro-5-(1-methylindol-2-yl)-2-pyridinyl]-3-methylbenzamide;N-[6-fluoro-5-(1-methylindol-2-yl)-2-pyridinyl]-4-methylbenzamide?
The InChIKey is LOIUVJAZNAEWJY-INCBJQFRSA-N. The full InChI is InChI=1S/2C22H18FN3O.C19H16F4N4O.C19H18F3N5O.C19H16F3N5O.2C18H22F3N5O/c1-14-6-5-8-16(12-14)22(27)25-20-11-10-17(21(23)24-20)19-13-15-7-3-4-9-18(15)26(19)2;1-14-7-9-15(10-8-14)22(27)25-20-12-11-17(21(23)24-20)19-13-16-5-3-4-6-18(16)26(19)2;1-3-27-14(10-15(26-27)19(21,22)23)13-7-8-16(24-17(13)20)25-18(28)12-6-4-5-11(2)9-12;2*1-27-14(11-15(26-27)19(20,21)22)13-8-9-16(25-18(13)23)24-17(28)10-7-12-5-3-2-4-6-12;1-26-13(10-14(25-26)18(19,20)21)12-7-8-15(24-17(12)22)23-16(27)9-6-11-4-2-3-5-11;1-26-13(10-14(25-26)18(19,20)21)12-7-8-15(24-17(12)22)23-16(27)9-11-5-3-2-4-6-11/h2*3-13H,1-2H3,(H,24,25,27);4-10H,3H2,1-2H3,(H,24,25,28);2-6,8-9,11H,7,10H2,1H3,(H3,23,24,25,28);2-11H,1H3,(H3,23,24,25,28);2*7-8,10-11H,2-6,9H2,1H3,(H3,22,23,24,27)/b;;;;10-7+;;.
What are the key properties of N-[6-amino-5-[1-methyl-3-(trifluoromethyl)pyrazol-5-yl]-2-pyridinyl]-2-cyclohexylacetamide;N-[6-amino-5-[1-methyl-3-(trifluoromethyl)pyrazol-5-yl]-2-pyridinyl]-3-cyclopentylpropanamide;N-[6-amino-5-[1-methyl-3-(trifluoromethyl)pyrazol-5-yl]-2-pyridinyl]-3-phenylpropanamide;(E)-N-[6-amino-5-[1-methyl-3-(trifluoromethyl)pyrazol-5-yl]-2-pyridinyl]-3-phenylprop-2-enamide;N-[5-[1-ethyl-3-(trifluoromethyl)pyrazol-5-yl]-6-fluoro-2-pyridinyl]-3-methylbenzamide;N-[6-fluoro-5-(1-methylindol-2-yl)-2-pyridinyl]-3-methylbenzamide;N-[6-fluoro-5-(1-methylindol-2-yl)-2-pyridinyl]-4-methylbenzamide?
N-[6-amino-5-[1-methyl-3-(trifluoromethyl)pyrazol-5-yl]-2-pyridinyl]-2-cyclohexylacetamide;N-[6-amino-5-[1-methyl-3-(trifluoromethyl)pyrazol-5-yl]-2-pyridinyl]-3-cyclopentylpropanamide;N-[6-amino-5-[1-methyl-3-(trifluoromethyl)pyrazol-5-yl]-2-pyridinyl]-3-phenylpropanamide;(E)-N-[6-amino-5-[1-methyl-3-(trifluoromethyl)pyrazol-5-yl]-2-pyridinyl]-3-phenylprop-2-enamide;N-[5-[1-ethyl-3-(trifluoromethyl)pyrazol-5-yl]-6-fluoro-2-pyridinyl]-3-methylbenzamide;N-[6-fluoro-5-(1-methylindol-2-yl)-2-pyridinyl]-3-methylbenzamide;N-[6-fluoro-5-(1-methylindol-2-yl)-2-pyridinyl]-4-methylbenzamide has a molecular weight of 2650.71 g/mol, XLogP of 29.94, 28 rotatable bonds, 11 hydrogen bond donors, and 30 hydrogen bond acceptors.
Where does this data come from?
All data for N-[6-amino-5-[1-methyl-3-(trifluoromethyl)pyrazol-5-yl]-2-pyridinyl]-2-cyclohexylacetamide;N-[6-amino-5-[1-methyl-3-(trifluoromethyl)pyrazol-5-yl]-2-pyridinyl]-3-cyclopentylpropanamide;N-[6-amino-5-[1-methyl-3-(trifluoromethyl)pyrazol-5-yl]-2-pyridinyl]-3-phenylpropanamide;(E)-N-[6-amino-5-[1-methyl-3-(trifluoromethyl)pyrazol-5-yl]-2-pyridinyl]-3-phenylprop-2-enamide;N-[5-[1-ethyl-3-(trifluoromethyl)pyrazol-5-yl]-6-fluoro-2-pyridinyl]-3-methylbenzamide;N-[6-fluoro-5-(1-methylindol-2-yl)-2-pyridinyl]-3-methylbenzamide;N-[6-fluoro-5-(1-methylindol-2-yl)-2-pyridinyl]-4-methylbenzamide is sourced from PubChem (CID 159409155), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).