2-methyl-N-(pyridin-2-ylmethyl)-1,8-naphthyridine-3-carboxamide;2-methyl-N-(pyridin-4-ylmethyl)-1,8-naphthyridine-3-carboxamide;2-methyl-N-[2-(1,3-thiazol-4-yl)ethyl]-1,8-naphthyridine-3-carboxamide;2-methyl-N-[[3-(trifluoromethyl)phenyl]methyl]-1,8-naphthyridine-3-carboxamide;N-(pyridin-2-ylmethyl)-2-(trifluoromethyl)-1,8-naphthyridine-3-carboxamide;N-(pyridin-4-ylmethyl)-2-(trifluoromethyl)-1,8-naphthyridine-3-carboxamide;2-(trifluoromethyl)-N-[[3-(trifluoromethyl)phenyl]methyl]-1,8-naphthyridine-3-carboxamide

C115H89F15N26O7S — CID 159480476

IUPAC2-methyl-N-(pyridin-2-ylmethyl)-1,8-naphthyridine-3-carboxamide;2-methyl-N-(pyridin-4-ylmethyl)-1,8-naphthyridine-3-carboxamide;2-methyl-N-[2-(1,3-thiazol-4-yl)ethyl]-1,8-naphthyridine-3-carboxamide;2-methyl-N-[[3-(trifluoromethyl)phenyl]methyl]-1,8-naphthyridine-3-carboxamide;N-(pyridin-2-ylmethyl)-2-(trifluoromethyl)-1,8-naphthyridine-3-carboxamide;N-(pyridin-4-ylmethyl)-2-(trifluoromethyl)-1,8-naphthyridine-3-carboxamide;2-(trifluoromethyl)-N-[[3-(trifluoromethyl)phenyl]methyl]-1,8-naphthyridine-3-carboxamide
SMILESCc1nc2ncccc2cc1C(=O)NCCc1cscn1.Cc1nc2ncccc2cc1C(=O)NCc1cccc(C(F)(F)F)c1.Cc1nc2ncccc2cc1C(=O)NCc1ccccn1.Cc1nc2ncccc2cc1C(=O)NCc1ccncc1.O=C(NCc1cccc(C(F)(F)F)c1)c1cc2cccnc2nc1C(F)(F)F.O=C(NCc1ccccn1)c1cc2cccnc2nc1C(F)(F)F.O=C(NCc1ccncc1)c1cc2cccnc2nc1C(F)(F)F
InChIInChI=1S/C18H11F6N3O.C18H14F3N3O.2C16H11F3N4O.2C16H14N4O.C15H14N4OS/c19-17(20,21)12-5-1-3-10(7-12)9-26-16(28)13-8-11-4-2-6-25-15(11)27-14(13)18(22,23)24;1-11-15(9-13-5-3-7-22-16(13)24-11)17(25)23-10-12-4-2-6-14(8-12)18(19,20)21;17-16(18,19)13-12(8-11-2-1-5-21-14(11)23-13)15(24)22-9-10-3-6-20-7-4-10;17-16(18,19)13-12(8-10-4-3-7-21-14(10)23-13)15(24)22-9-11-5-1-2-6-20-11;1-11-14(9-13-3-2-6-18-15(13)20-11)16(21)19-10-12-4-7-17-8-5-12;1-11-14(9-12-5-4-8-18-15(12)20-11)16(21)19-10-13-6-2-3-7-17-13;1-10-13(7-11-3-2-5-16-14(11)19-10)15(20)17-6-4-12-8-21-9-18-12/h1-8H,9H2,(H,26,28);2-9H,10H2,1H3,(H,23,25);2*1-8H,9H2,(H,22,24);2*2-9H,10H2,1H3,(H,19,21);2-3,5,7-9H,4,6H2,1H3,(H,17,20)
InChIKeyLWYALMNNTUMXBQ-UHFFFAOYSA-N
MW2264.19 g/mol
LogP21.33
Rot. Bonds22

About 2-methyl-N-(pyridin-2-ylmethyl)-1,8-naphthyridine-3-carboxamide;2-methyl-N-(pyridin-4-ylmethyl)-1,8-naphthyridine-3-carboxamide;2-methyl-N-[2-(1,3-thiazol-4-yl)ethyl]-1,8-naphthyridine-3-carboxamide;2-methyl-N-[[3-(trifluoromethyl)phenyl]methyl]-1,8-naphthyridine-3-carboxamide;N-(pyridin-2-ylmethyl)-2-(trifluoromethyl)-1,8-naphthyridine-3-carboxamide;N-(pyridin-4-ylmethyl)-2-(trifluoromethyl)-1,8-naphthyridine-3-carboxamide;2-(trifluoromethyl)-N-[[3-(trifluoromethyl)phenyl]methyl]-1,8-naphthyridine-3-carboxamide

2-methyl-N-(pyridin-2-ylmethyl)-1,8-naphthyridine-3-carboxamide;2-methyl-N-(pyridin-4-ylmethyl)-1,8-naphthyridine-3-carboxamide;2-methyl-N-[2-(1,3-thiazol-4-yl)ethyl]-1,8-naphthyridine-3-carboxamide;2-methyl-N-[[3-(trifluoromethyl)phenyl]methyl]-1,8-naphthyridine-3-carboxamide;N-(pyridin-2-ylmethyl)-2-(trifluoromethyl)-1,8-naphthyridine-3-carboxamide;N-(pyridin-4-ylmethyl)-2-(trifluoromethyl)-1,8-naphthyridine-3-carboxamide;2-(trifluoromethyl)-N-[[3-(trifluoromethyl)phenyl]methyl]-1,8-naphthyridine-3-carboxamide (PubChem CID 159480476) has the molecular formula C115H89F15N26O7S and a molecular weight of 2264.19 g/mol. Its IUPAC name is 2-methyl-N-(pyridin-2-ylmethyl)-1,8-naphthyridine-3-carboxamide;2-methyl-N-(pyridin-4-ylmethyl)-1,8-naphthyridine-3-carboxamide;2-methyl-N-[2-(1,3-thiazol-4-yl)ethyl]-1,8-naphthyridine-3-carboxamide;2-methyl-N-[[3-(trifluoromethyl)phenyl]methyl]-1,8-naphthyridine-3-carboxamide;N-(pyridin-2-ylmethyl)-2-(trifluoromethyl)-1,8-naphthyridine-3-carboxamide;N-(pyridin-4-ylmethyl)-2-(trifluoromethyl)-1,8-naphthyridine-3-carboxamide;2-(trifluoromethyl)-N-[[3-(trifluoromethyl)phenyl]methyl]-1,8-naphthyridine-3-carboxamide.

Molecular Properties

Compound Name2-methyl-N-(pyridin-2-ylmethyl)-1,8-naphthyridine-3-carboxamide;2-methyl-N-(pyridin-4-ylmethyl)-1,8-naphthyridine-3-carboxamide;2-methyl-N-[2-(1,3-thiazol-4-yl)ethyl]-1,8-naphthyridine-3-carboxamide;2-methyl-N-[[3-(trifluoromethyl)phenyl]methyl]-1,8-naphthyridine-3-carboxamide;N-(pyridin-2-ylmethyl)-2-(trifluoromethyl)-1,8-naphthyridine-3-carboxamide;N-(pyridin-4-ylmethyl)-2-(trifluoromethyl)-1,8-naphthyridine-3-carboxamide;2-(trifluoromethyl)-N-[[3-(trifluoromethyl)phenyl]methyl]-1,8-naphthyridine-3-carboxamide
PubChem CID159480476
Molecular FormulaC115H89F15N26O7S
Molecular Weight2264.19 g/mol
Exact Mass2262.69
IUPAC Name2-methyl-N-(pyridin-2-ylmethyl)-1,8-naphthyridine-3-carboxamide;2-methyl-N-(pyridin-4-ylmethyl)-1,8-naphthyridine-3-carboxamide;2-methyl-N-[2-(1,3-thiazol-4-yl)ethyl]-1,8-naphthyridine-3-carboxamide;2-methyl-N-[[3-(trifluoromethyl)phenyl]methyl]-1,8-naphthyridine-3-carboxamide;N-(pyridin-2-ylmethyl)-2-(trifluoromethyl)-1,8-naphthyridine-3-carboxamide;N-(pyridin-4-ylmethyl)-2-(trifluoromethyl)-1,8-naphthyridine-3-carboxamide;2-(trifluoromethyl)-N-[[3-(trifluoromethyl)phenyl]methyl]-1,8-naphthyridine-3-carboxamide
SMILESCc1nc2ncccc2cc1C(=O)NCCc1cscn1.Cc1nc2ncccc2cc1C(=O)NCc1cccc(C(F)(F)F)c1.Cc1nc2ncccc2cc1C(=O)NCc1ccccn1.Cc1nc2ncccc2cc1C(=O)NCc1ccncc1.O=C(NCc1cccc(C(F)(F)F)c1)c1cc2cccnc2nc1C(F)(F)F.O=C(NCc1ccccn1)c1cc2cccnc2nc1C(F)(F)F.O=C(NCc1ccncc1)c1cc2cccnc2nc1C(F)(F)F
InChIInChI=1S/C18H11F6N3O.C18H14F3N3O.2C16H11F3N4O.2C16H14N4O.C15H14N4OS/c19-17(20,21)12-5-1-3-10(7-12)9-26-16(28)13-8-11-4-2-6-25-15(11)27-14(13)18(22,23)24;1-11-15(9-13-5-3-7-22-16(13)24-11)17(25)23-10-12-4-2-6-14(8-12)18(19,20)21;17-16(18,19)13-12(8-11-2-1-5-21-14(11)23-13)15(24)22-9-10-3-6-20-7-4-10;17-16(18,19)13-12(8-10-4-3-7-21-14(10)23-13)15(24)22-9-11-5-1-2-6-20-11;1-11-14(9-13-3-2-6-18-15(13)20-11)16(21)19-10-12-4-7-17-8-5-12;1-11-14(9-12-5-4-8-18-15(12)20-11)16(21)19-10-13-6-2-3-7-17-13;1-10-13(7-11-3-2-5-16-14(11)19-10)15(20)17-6-4-12-8-21-9-18-12/h1-8H,9H2,(H,26,28);2-9H,10H2,1H3,(H,23,25);2*1-8H,9H2,(H,22,24);2*2-9H,10H2,1H3,(H,19,21);2-3,5,7-9H,4,6H2,1H3,(H,17,20)
InChIKeyLWYALMNNTUMXBQ-UHFFFAOYSA-N
XLogP21.33
TPSA448.61 Ų
H-Bond Donors7
H-Bond Acceptors27
Rotatable Bonds22
Heavy Atoms164
Complexity—

Lipinski Rule of Five

4 violations

RuleValue
MW ≤ 5002264.19
LogP ≤ 521.33
H-Bond Donors ≤ 57
H-Bond Acceptors ≤ 1027

Analyze 2-methyl-N-(pyridin-2-ylmethyl)-1,8-naphthyridine-3-carboxamide;2-methyl-N-(pyridin-4-ylmethyl)-1,8-naphthyridine-3-carboxamide;2-methyl-N-[2-(1,3-thiazol-4-yl)ethyl]-1,8-naphthyridine-3-carboxamide;2-methyl-N-[[3-(trifluoromethyl)phenyl]methyl]-1,8-naphthyridine-3-carboxamide;N-(pyridin-2-ylmethyl)-2-(trifluoromethyl)-1,8-naphthyridine-3-carboxamide;N-(pyridin-4-ylmethyl)-2-(trifluoromethyl)-1,8-naphthyridine-3-carboxamide;2-(trifluoromethyl)-N-[[3-(trifluoromethyl)phenyl]methyl]-1,8-naphthyridine-3-carboxamide with MolForge

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Related Compounds

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US20250090540, Example I-209
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[5-(4-Fluorophenyl)-2-methyl-1,3-thiazol-4-yl]-[2-[(1,8-naphthyridin-2-ylamino)methyl]piperidin-1-yl]methanone
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N-[4-[6-fluoro-1-[3-[4-[[4-(4-methylpiperazin-1-yl)piperidin-1-yl]methyl]phenyl]phenyl]-2,4-dioxopyrido[2,3-d]pyrimidin-3-yl]cyclohexyl]-2-methyl-1,3-thiazole-4-carboxamide
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N-[4-[6-fluoro-2,4-dioxo-1-(thian-4-yl)pyrido[2,3-d]pyrimidin-3-yl]cyclohexyl]-2-methyl-4-[2-(3-methylphenyl)ethyl]-1,3-thiazole-5-carboxamide
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3-(8-(2,6-difluorophenyl)-2-{[2-(dimethylamino)ethyl]amino}-7-oxo-5,6,7,8-tetrahydropyrimido[4,5-d]pyrimidin-4-yl)-N-1,3-thiazol-2-ylbenzamide
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[4-[4-[4-(2,6-Naphthyridin-1-yl)piperazine-1-carbonyl]-1,3-thiazol-2-yl]piperidin-1-yl]-[2-[4-(trifluoromethyl)phenyl]phenyl]methanone
CID 59210265

Frequently Asked Questions

What is the IUPAC name of 2-methyl-N-(pyridin-2-ylmethyl)-1,8-naphthyridine-3-carboxamide;2-methyl-N-(pyridin-4-ylmethyl)-1,8-naphthyridine-3-carboxamide;2-methyl-N-[2-(1,3-thiazol-4-yl)ethyl]-1,8-naphthyridine-3-carboxamide;2-methyl-N-[[3-(trifluoromethyl)phenyl]methyl]-1,8-naphthyridine-3-carboxamide;N-(pyridin-2-ylmethyl)-2-(trifluoromethyl)-1,8-naphthyridine-3-carboxamide;N-(pyridin-4-ylmethyl)-2-(trifluoromethyl)-1,8-naphthyridine-3-carboxamide;2-(trifluoromethyl)-N-[[3-(trifluoromethyl)phenyl]methyl]-1,8-naphthyridine-3-carboxamide?
The IUPAC name of 2-methyl-N-(pyridin-2-ylmethyl)-1,8-naphthyridine-3-carboxamide;2-methyl-N-(pyridin-4-ylmethyl)-1,8-naphthyridine-3-carboxamide;2-methyl-N-[2-(1,3-thiazol-4-yl)ethyl]-1,8-naphthyridine-3-carboxamide;2-methyl-N-[[3-(trifluoromethyl)phenyl]methyl]-1,8-naphthyridine-3-carboxamide;N-(pyridin-2-ylmethyl)-2-(trifluoromethyl)-1,8-naphthyridine-3-carboxamide;N-(pyridin-4-ylmethyl)-2-(trifluoromethyl)-1,8-naphthyridine-3-carboxamide;2-(trifluoromethyl)-N-[[3-(trifluoromethyl)phenyl]methyl]-1,8-naphthyridine-3-carboxamide (CID 159480476) is 2-methyl-N-(pyridin-2-ylmethyl)-1,8-naphthyridine-3-carboxamide;2-methyl-N-(pyridin-4-ylmethyl)-1,8-naphthyridine-3-carboxamide;2-methyl-N-[2-(1,3-thiazol-4-yl)ethyl]-1,8-naphthyridine-3-carboxamide;2-methyl-N-[[3-(trifluoromethyl)phenyl]methyl]-1,8-naphthyridine-3-carboxamide;N-(pyridin-2-ylmethyl)-2-(trifluoromethyl)-1,8-naphthyridine-3-carboxamide;N-(pyridin-4-ylmethyl)-2-(trifluoromethyl)-1,8-naphthyridine-3-carboxamide;2-(trifluoromethyl)-N-[[3-(trifluoromethyl)phenyl]methyl]-1,8-naphthyridine-3-carboxamide.
What is the SMILES notation for 2-methyl-N-(pyridin-2-ylmethyl)-1,8-naphthyridine-3-carboxamide;2-methyl-N-(pyridin-4-ylmethyl)-1,8-naphthyridine-3-carboxamide;2-methyl-N-[2-(1,3-thiazol-4-yl)ethyl]-1,8-naphthyridine-3-carboxamide;2-methyl-N-[[3-(trifluoromethyl)phenyl]methyl]-1,8-naphthyridine-3-carboxamide;N-(pyridin-2-ylmethyl)-2-(trifluoromethyl)-1,8-naphthyridine-3-carboxamide;N-(pyridin-4-ylmethyl)-2-(trifluoromethyl)-1,8-naphthyridine-3-carboxamide;2-(trifluoromethyl)-N-[[3-(trifluoromethyl)phenyl]methyl]-1,8-naphthyridine-3-carboxamide?
The canonical SMILES for 2-methyl-N-(pyridin-2-ylmethyl)-1,8-naphthyridine-3-carboxamide;2-methyl-N-(pyridin-4-ylmethyl)-1,8-naphthyridine-3-carboxamide;2-methyl-N-[2-(1,3-thiazol-4-yl)ethyl]-1,8-naphthyridine-3-carboxamide;2-methyl-N-[[3-(trifluoromethyl)phenyl]methyl]-1,8-naphthyridine-3-carboxamide;N-(pyridin-2-ylmethyl)-2-(trifluoromethyl)-1,8-naphthyridine-3-carboxamide;N-(pyridin-4-ylmethyl)-2-(trifluoromethyl)-1,8-naphthyridine-3-carboxamide;2-(trifluoromethyl)-N-[[3-(trifluoromethyl)phenyl]methyl]-1,8-naphthyridine-3-carboxamide is Cc1nc2ncccc2cc1C(=O)NCCc1cscn1.Cc1nc2ncccc2cc1C(=O)NCc1cccc(C(F)(F)F)c1.Cc1nc2ncccc2cc1C(=O)NCc1ccccn1.Cc1nc2ncccc2cc1C(=O)NCc1ccncc1.O=C(NCc1cccc(C(F)(F)F)c1)c1cc2cccnc2nc1C(F)(F)F.O=C(NCc1ccccn1)c1cc2cccnc2nc1C(F)(F)F.O=C(NCc1ccncc1)c1cc2cccnc2nc1C(F)(F)F.
What is the InChIKey of 2-methyl-N-(pyridin-2-ylmethyl)-1,8-naphthyridine-3-carboxamide;2-methyl-N-(pyridin-4-ylmethyl)-1,8-naphthyridine-3-carboxamide;2-methyl-N-[2-(1,3-thiazol-4-yl)ethyl]-1,8-naphthyridine-3-carboxamide;2-methyl-N-[[3-(trifluoromethyl)phenyl]methyl]-1,8-naphthyridine-3-carboxamide;N-(pyridin-2-ylmethyl)-2-(trifluoromethyl)-1,8-naphthyridine-3-carboxamide;N-(pyridin-4-ylmethyl)-2-(trifluoromethyl)-1,8-naphthyridine-3-carboxamide;2-(trifluoromethyl)-N-[[3-(trifluoromethyl)phenyl]methyl]-1,8-naphthyridine-3-carboxamide?
The InChIKey is LWYALMNNTUMXBQ-UHFFFAOYSA-N. The full InChI is InChI=1S/C18H11F6N3O.C18H14F3N3O.2C16H11F3N4O.2C16H14N4O.C15H14N4OS/c19-17(20,21)12-5-1-3-10(7-12)9-26-16(28)13-8-11-4-2-6-25-15(11)27-14(13)18(22,23)24;1-11-15(9-13-5-3-7-22-16(13)24-11)17(25)23-10-12-4-2-6-14(8-12)18(19,20)21;17-16(18,19)13-12(8-11-2-1-5-21-14(11)23-13)15(24)22-9-10-3-6-20-7-4-10;17-16(18,19)13-12(8-10-4-3-7-21-14(10)23-13)15(24)22-9-11-5-1-2-6-20-11;1-11-14(9-13-3-2-6-18-15(13)20-11)16(21)19-10-12-4-7-17-8-5-12;1-11-14(9-12-5-4-8-18-15(12)20-11)16(21)19-10-13-6-2-3-7-17-13;1-10-13(7-11-3-2-5-16-14(11)19-10)15(20)17-6-4-12-8-21-9-18-12/h1-8H,9H2,(H,26,28);2-9H,10H2,1H3,(H,23,25);2*1-8H,9H2,(H,22,24);2*2-9H,10H2,1H3,(H,19,21);2-3,5,7-9H,4,6H2,1H3,(H,17,20).
What are the key properties of 2-methyl-N-(pyridin-2-ylmethyl)-1,8-naphthyridine-3-carboxamide;2-methyl-N-(pyridin-4-ylmethyl)-1,8-naphthyridine-3-carboxamide;2-methyl-N-[2-(1,3-thiazol-4-yl)ethyl]-1,8-naphthyridine-3-carboxamide;2-methyl-N-[[3-(trifluoromethyl)phenyl]methyl]-1,8-naphthyridine-3-carboxamide;N-(pyridin-2-ylmethyl)-2-(trifluoromethyl)-1,8-naphthyridine-3-carboxamide;N-(pyridin-4-ylmethyl)-2-(trifluoromethyl)-1,8-naphthyridine-3-carboxamide;2-(trifluoromethyl)-N-[[3-(trifluoromethyl)phenyl]methyl]-1,8-naphthyridine-3-carboxamide?
2-methyl-N-(pyridin-2-ylmethyl)-1,8-naphthyridine-3-carboxamide;2-methyl-N-(pyridin-4-ylmethyl)-1,8-naphthyridine-3-carboxamide;2-methyl-N-[2-(1,3-thiazol-4-yl)ethyl]-1,8-naphthyridine-3-carboxamide;2-methyl-N-[[3-(trifluoromethyl)phenyl]methyl]-1,8-naphthyridine-3-carboxamide;N-(pyridin-2-ylmethyl)-2-(trifluoromethyl)-1,8-naphthyridine-3-carboxamide;N-(pyridin-4-ylmethyl)-2-(trifluoromethyl)-1,8-naphthyridine-3-carboxamide;2-(trifluoromethyl)-N-[[3-(trifluoromethyl)phenyl]methyl]-1,8-naphthyridine-3-carboxamide has a molecular weight of 2264.19 g/mol, XLogP of 21.33, 22 rotatable bonds, 7 hydrogen bond donors, and 27 hydrogen bond acceptors.
Where does this data come from?
All data for 2-methyl-N-(pyridin-2-ylmethyl)-1,8-naphthyridine-3-carboxamide;2-methyl-N-(pyridin-4-ylmethyl)-1,8-naphthyridine-3-carboxamide;2-methyl-N-[2-(1,3-thiazol-4-yl)ethyl]-1,8-naphthyridine-3-carboxamide;2-methyl-N-[[3-(trifluoromethyl)phenyl]methyl]-1,8-naphthyridine-3-carboxamide;N-(pyridin-2-ylmethyl)-2-(trifluoromethyl)-1,8-naphthyridine-3-carboxamide;N-(pyridin-4-ylmethyl)-2-(trifluoromethyl)-1,8-naphthyridine-3-carboxamide;2-(trifluoromethyl)-N-[[3-(trifluoromethyl)phenyl]methyl]-1,8-naphthyridine-3-carboxamide is sourced from PubChem (CID 159480476), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).