5-(2-aminopyrimidin-5-yl)-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;6-chloro-5-(1H-imidazol-2-yl)-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;5-[1-(2-hydroxyethyl)pyrazol-4-yl]-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;6-(2-hydroxypropan-2-yl)-5-pyrimidin-5-yl-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;5-(2-methoxy-3-pyridinyl)-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;2-(2-methoxypyrimidin-5-yl)-N-[4-(trifluoromethoxy)phenyl]pyridine-4-carboxamide;5-(2-oxo-1H-pyridin-3-yl)-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;6-pyrimidin-5-yl-N-[4-(trifluoromethoxy)phenyl]pyrazine-2-carboxamide;2-pyrimidin-5-yl-N-[4-(trifluoromethoxy)phenyl]pyridine-4-carboxamide;4-pyrimidin-5-yl-N-[4-(trifluoromethoxy)phenyl]pyridine-2-carboxamide

C176H125ClF30N40O25 — CID 159480833

IUPAC5-(2-aminopyrimidin-5-yl)-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;6-chloro-5-(1H-imidazol-2-yl)-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;5-[1-(2-hydroxyethyl)pyrazol-4-yl]-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;6-(2-hydroxypropan-2-yl)-5-pyrimidin-5-yl-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;5-(2-methoxy-3-pyridinyl)-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;2-(2-methoxypyrimidin-5-yl)-N-[4-(trifluoromethoxy)phenyl]pyridine-4-carboxamide;5-(2-oxo-1H-pyridin-3-yl)-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;6-pyrimidin-5-yl-N-[4-(trifluoromethoxy)phenyl]pyrazine-2-carboxamide;2-pyrimidin-5-yl-N-[4-(trifluoromethoxy)phenyl]pyridine-4-carboxamide;4-pyrimidin-5-yl-N-[4-(trifluoromethoxy)phenyl]pyridine-2-carboxamide
SMILESCC(C)(O)c1ncc(C(=O)Nc2ccc(OC(F)(F)F)cc2)cc1-c1cncnc1.COc1ncc(-c2cc(C(=O)Nc3ccc(OC(F)(F)F)cc3)ccn2)cn1.COc1ncccc1-c1cncc(C(=O)Nc2ccc(OC(F)(F)F)cc2)c1.Nc1ncc(-c2cncc(C(=O)Nc3ccc(OC(F)(F)F)cc3)c2)cn1.O=C(Nc1ccc(OC(F)(F)F)cc1)c1cc(-c2cncnc2)ccn1.O=C(Nc1ccc(OC(F)(F)F)cc1)c1ccnc(-c2cncnc2)c1.O=C(Nc1ccc(OC(F)(F)F)cc1)c1cnc(Cl)c(-c2ncc[nH]2)c1.O=C(Nc1ccc(OC(F)(F)F)cc1)c1cncc(-c2ccc[nH]c2=O)c1.O=C(Nc1ccc(OC(F)(F)F)cc1)c1cncc(-c2cncnc2)n1.O=C(Nc1ccc(OC(F)(F)F)cc1)c1cncc(-c2cnn(CCO)c2)c1
InChIInChI=1S/C20H17F3N4O3.C19H14F3N3O3.C18H13F3N4O3.C18H15F3N4O3.C18H12F3N3O3.C17H12F3N5O2.2C17H11F3N4O2.C16H10ClF3N4O2.C16H10F3N5O2/c1-19(2,29)17-16(13-8-24-11-25-9-13)7-12(10-26-17)18(28)27-14-3-5-15(6-4-14)30-20(21,22)23;1-27-18-16(3-2-8-24-18)12-9-13(11-23-10-12)17(26)25-14-4-6-15(7-5-14)28-19(20,21)22;1-27-17-23-9-12(10-24-17)15-8-11(6-7-22-15)16(26)25-13-2-4-14(5-3-13)28-18(19,20)21;19-18(20,21)28-16-3-1-15(2-4-16)24-17(27)13-7-12(8-22-9-13)14-10-23-25(11-14)5-6-26;19-18(20,21)27-14-5-3-13(4-6-14)24-16(25)12-8-11(9-22-10-12)15-2-1-7-23-17(15)26;18-17(19,20)27-14-3-1-13(2-4-14)25-15(26)11-5-10(6-22-7-11)12-8-23-16(21)24-9-12;18-17(19,20)26-14-3-1-13(2-4-14)24-16(25)11-5-6-23-15(7-11)12-8-21-10-22-9-12;18-17(19,20)26-14-3-1-13(2-4-14)24-16(25)15-7-11(5-6-23-15)12-8-21-10-22-9-12;17-13-12(14-21-5-6-22-14)7-9(8-23-13)15(25)24-10-1-3-11(4-2-10)26-16(18,19)20;17-16(18,19)26-12-3-1-11(2-4-12)23-15(25)14-8-20-7-13(24-14)10-5-21-9-22-6-10/h3-11,29H,1-2H3,(H,27,28);2-11H,1H3,(H,25,26);2-10H,1H3,(H,25,26);1-4,7-11,26H,5-6H2,(H,24,27);1-10H,(H,23,26)(H,24,25);1-9H,(H,25,26)(H2,21,23,24);2*1-10H,(H,24,25);1-8H,(H,21,22)(H,24,25);1-9H,(H,23,25)
InChIKeyLWZDWJBNURMNFD-UHFFFAOYSA-N
MW3805.58 g/mol
LogP36.61
Rot. Bonds45

About 5-(2-aminopyrimidin-5-yl)-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;6-chloro-5-(1H-imidazol-2-yl)-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;5-[1-(2-hydroxyethyl)pyrazol-4-yl]-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;6-(2-hydroxypropan-2-yl)-5-pyrimidin-5-yl-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;5-(2-methoxy-3-pyridinyl)-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;2-(2-methoxypyrimidin-5-yl)-N-[4-(trifluoromethoxy)phenyl]pyridine-4-carboxamide;5-(2-oxo-1H-pyridin-3-yl)-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;6-pyrimidin-5-yl-N-[4-(trifluoromethoxy)phenyl]pyrazine-2-carboxamide;2-pyrimidin-5-yl-N-[4-(trifluoromethoxy)phenyl]pyridine-4-carboxamide;4-pyrimidin-5-yl-N-[4-(trifluoromethoxy)phenyl]pyridine-2-carboxamide

5-(2-aminopyrimidin-5-yl)-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;6-chloro-5-(1H-imidazol-2-yl)-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;5-[1-(2-hydroxyethyl)pyrazol-4-yl]-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;6-(2-hydroxypropan-2-yl)-5-pyrimidin-5-yl-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;5-(2-methoxy-3-pyridinyl)-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;2-(2-methoxypyrimidin-5-yl)-N-[4-(trifluoromethoxy)phenyl]pyridine-4-carboxamide;5-(2-oxo-1H-pyridin-3-yl)-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;6-pyrimidin-5-yl-N-[4-(trifluoromethoxy)phenyl]pyrazine-2-carboxamide;2-pyrimidin-5-yl-N-[4-(trifluoromethoxy)phenyl]pyridine-4-carboxamide;4-pyrimidin-5-yl-N-[4-(trifluoromethoxy)phenyl]pyridine-2-carboxamide (PubChem CID 159480833) has the molecular formula C176H125ClF30N40O25 and a molecular weight of 3805.58 g/mol. Its IUPAC name is 5-(2-aminopyrimidin-5-yl)-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;6-chloro-5-(1H-imidazol-2-yl)-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;5-[1-(2-hydroxyethyl)pyrazol-4-yl]-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;6-(2-hydroxypropan-2-yl)-5-pyrimidin-5-yl-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;5-(2-methoxy-3-pyridinyl)-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;2-(2-methoxypyrimidin-5-yl)-N-[4-(trifluoromethoxy)phenyl]pyridine-4-carboxamide;5-(2-oxo-1H-pyridin-3-yl)-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;6-pyrimidin-5-yl-N-[4-(trifluoromethoxy)phenyl]pyrazine-2-carboxamide;2-pyrimidin-5-yl-N-[4-(trifluoromethoxy)phenyl]pyridine-4-carboxamide;4-pyrimidin-5-yl-N-[4-(trifluoromethoxy)phenyl]pyridine-2-carboxamide.

Molecular Properties

Compound Name5-(2-aminopyrimidin-5-yl)-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;6-chloro-5-(1H-imidazol-2-yl)-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;5-[1-(2-hydroxyethyl)pyrazol-4-yl]-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;6-(2-hydroxypropan-2-yl)-5-pyrimidin-5-yl-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;5-(2-methoxy-3-pyridinyl)-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;2-(2-methoxypyrimidin-5-yl)-N-[4-(trifluoromethoxy)phenyl]pyridine-4-carboxamide;5-(2-oxo-1H-pyridin-3-yl)-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;6-pyrimidin-5-yl-N-[4-(trifluoromethoxy)phenyl]pyrazine-2-carboxamide;2-pyrimidin-5-yl-N-[4-(trifluoromethoxy)phenyl]pyridine-4-carboxamide;4-pyrimidin-5-yl-N-[4-(trifluoromethoxy)phenyl]pyridine-2-carboxamide
PubChem CID159480833
Molecular FormulaC176H125ClF30N40O25
Molecular Weight3805.58 g/mol
Exact Mass3802.89
IUPAC Name5-(2-aminopyrimidin-5-yl)-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;6-chloro-5-(1H-imidazol-2-yl)-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;5-[1-(2-hydroxyethyl)pyrazol-4-yl]-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;6-(2-hydroxypropan-2-yl)-5-pyrimidin-5-yl-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;5-(2-methoxy-3-pyridinyl)-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;2-(2-methoxypyrimidin-5-yl)-N-[4-(trifluoromethoxy)phenyl]pyridine-4-carboxamide;5-(2-oxo-1H-pyridin-3-yl)-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;6-pyrimidin-5-yl-N-[4-(trifluoromethoxy)phenyl]pyrazine-2-carboxamide;2-pyrimidin-5-yl-N-[4-(trifluoromethoxy)phenyl]pyridine-4-carboxamide;4-pyrimidin-5-yl-N-[4-(trifluoromethoxy)phenyl]pyridine-2-carboxamide
SMILESCC(C)(O)c1ncc(C(=O)Nc2ccc(OC(F)(F)F)cc2)cc1-c1cncnc1.COc1ncc(-c2cc(C(=O)Nc3ccc(OC(F)(F)F)cc3)ccn2)cn1.COc1ncccc1-c1cncc(C(=O)Nc2ccc(OC(F)(F)F)cc2)c1.Nc1ncc(-c2cncc(C(=O)Nc3ccc(OC(F)(F)F)cc3)c2)cn1.O=C(Nc1ccc(OC(F)(F)F)cc1)c1cc(-c2cncnc2)ccn1.O=C(Nc1ccc(OC(F)(F)F)cc1)c1ccnc(-c2cncnc2)c1.O=C(Nc1ccc(OC(F)(F)F)cc1)c1cnc(Cl)c(-c2ncc[nH]2)c1.O=C(Nc1ccc(OC(F)(F)F)cc1)c1cncc(-c2ccc[nH]c2=O)c1.O=C(Nc1ccc(OC(F)(F)F)cc1)c1cncc(-c2cncnc2)n1.O=C(Nc1ccc(OC(F)(F)F)cc1)c1cncc(-c2cnn(CCO)c2)c1
InChIInChI=1S/C20H17F3N4O3.C19H14F3N3O3.C18H13F3N4O3.C18H15F3N4O3.C18H12F3N3O3.C17H12F3N5O2.2C17H11F3N4O2.C16H10ClF3N4O2.C16H10F3N5O2/c1-19(2,29)17-16(13-8-24-11-25-9-13)7-12(10-26-17)18(28)27-14-3-5-15(6-4-14)30-20(21,22)23;1-27-18-16(3-2-8-24-18)12-9-13(11-23-10-12)17(26)25-14-4-6-15(7-5-14)28-19(20,21)22;1-27-17-23-9-12(10-24-17)15-8-11(6-7-22-15)16(26)25-13-2-4-14(5-3-13)28-18(19,20)21;19-18(20,21)28-16-3-1-15(2-4-16)24-17(27)13-7-12(8-22-9-13)14-10-23-25(11-14)5-6-26;19-18(20,21)27-14-5-3-13(4-6-14)24-16(25)12-8-11(9-22-10-12)15-2-1-7-23-17(15)26;18-17(19,20)27-14-3-1-13(2-4-14)25-15(26)11-5-10(6-22-7-11)12-8-23-16(21)24-9-12;18-17(19,20)26-14-3-1-13(2-4-14)24-16(25)11-5-6-23-15(7-11)12-8-21-10-22-9-12;18-17(19,20)26-14-3-1-13(2-4-14)24-16(25)15-7-11(5-6-23-15)12-8-21-10-22-9-12;17-13-12(14-21-5-6-22-14)7-9(8-23-13)15(25)24-10-1-3-11(4-2-10)26-16(18,19)20;17-16(18,19)26-12-3-1-11(2-4-12)23-15(25)14-8-20-7-13(24-14)10-5-21-9-22-6-10/h3-11,29H,1-2H3,(H,27,28);2-11H,1H3,(H,25,26);2-10H,1H3,(H,25,26);1-4,7-11,26H,5-6H2,(H,24,27);1-10H,(H,23,26)(H,24,25);1-9H,(H,25,26)(H2,21,23,24);2*1-10H,(H,24,25);1-8H,(H,21,22)(H,24,25);1-9H,(H,23,25)
InChIKeyLWZDWJBNURMNFD-UHFFFAOYSA-N
XLogP36.61
TPSA856.96 Ų
H-Bond Donors15
H-Bond Acceptors53
Rotatable Bonds45
Heavy Atoms272
Complexity—

Lipinski Rule of Five

4 violations

RuleValue
MW ≤ 5003805.58
LogP ≤ 536.61
H-Bond Donors ≤ 515
H-Bond Acceptors ≤ 1053

Computed Properties (RDKit)

Structural Alerts{'alert_name': '2-halo_pyridine', 'substructure': 'N/A'}

Analyze 5-(2-aminopyrimidin-5-yl)-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;6-chloro-5-(1H-imidazol-2-yl)-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;5-[1-(2-hydroxyethyl)pyrazol-4-yl]-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;6-(2-hydroxypropan-2-yl)-5-pyrimidin-5-yl-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;5-(2-methoxy-3-pyridinyl)-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;2-(2-methoxypyrimidin-5-yl)-N-[4-(trifluoromethoxy)phenyl]pyridine-4-carboxamide;5-(2-oxo-1H-pyridin-3-yl)-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;6-pyrimidin-5-yl-N-[4-(trifluoromethoxy)phenyl]pyrazine-2-carboxamide;2-pyrimidin-5-yl-N-[4-(trifluoromethoxy)phenyl]pyridine-4-carboxamide;4-pyrimidin-5-yl-N-[4-(trifluoromethoxy)phenyl]pyridine-2-carboxamide with MolForge

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Related Compounds

6-chloro-N-[4-[chloro(difluoro)methoxy]phenyl]-5-pyrimidin-5-ylpyridine-3-carboxamide;6-chloro-5-(5-fluoro-3-pyridinyl)-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;5-(5-fluoro-3-pyridinyl)-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;2-fluoro-5-pyrimidin-5-yl-N-[4-(trifluoromethoxy)phenyl]benzamide;2-(2-methoxypyrimidin-5-yl)-N-[4-(trifluoromethoxy)phenyl]pyridine-4-carboxamide;5-pyridin-3-yl-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;6-pyrimidin-5-yl-N-[4-(trifluoromethoxy)phenyl]pyrazine-2-carboxamide;2-pyrimidin-5-yl-N-[4-(trifluoromethoxy)phenyl]pyridine-4-carboxamide;4-pyrimidin-5-yl-N-[4-(trifluoromethoxy)phenyl]pyridine-2-carboxamide;6-pyrimidin-5-yl-N-[4-(trifluoromethoxy)phenyl]pyridine-2-carboxamide
CID 158547225
N-[4-[chloro(difluoro)methoxy]phenyl]-6-[(3R)-3-hydroxypiperidin-1-yl]-5-(1H-pyrazol-5-yl)pyridine-3-carboxamide;N-[4-[chloro(difluoro)methoxy]phenyl]-6-[(3S)-3-hydroxypiperidin-1-yl]-5-(1H-pyrazol-5-yl)pyridine-3-carboxamide;N-[4-[chloro(difluoro)methoxy]phenyl]-6-(4-hydroxypiperidin-1-yl)-5-(1H-pyrazol-5-yl)pyridine-3-carboxamide;N-[4-[chloro(difluoro)methoxy]phenyl]-6-[(3R)-3-hydroxypyrrolidin-1-yl]-5-(1H-imidazol-2-yl)pyridine-3-carboxamide;6-(3-hydroxy-3-methylazetidin-1-yl)-5-(1H-imidazol-2-yl)-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;6-[(3R)-3-hydroxypyrrolidin-1-yl]-5-(1H-imidazol-2-yl)-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;5-(5-methyl-1H-imidazol-2-yl)-6-[(3R)-3-methylpyrrolidin-1-yl]-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide
CID 158790696
4-chloro-3-(1-methylpyrazol-4-yl)-N-[4-(trifluoromethoxy)phenyl]benzamide;4-chloro-3-(1H-pyrazol-5-yl)-N-[4-(trifluoromethoxy)phenyl]benzamide;4-chloro-3-pyridin-3-yl-N-[4-(trifluoromethoxy)phenyl]benzamide;4-chloro-3-pyridin-4-yl-N-[4-(trifluoromethoxy)phenyl]benzamide;6-(3,6-dihydro-2H-pyran-4-yl)-5-pyrimidin-5-yl-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;6-methyl-5-pyrimidin-5-yl-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;6-(oxan-4-yl)-5-pyrimidin-5-yl-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;5-pyrimidin-5-yl-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide
CID 159610291
4-chloro-3-(1-methylpyrazol-4-yl)-N-[4-(trifluoromethoxy)phenyl]benzamide;4-chloro-3-(1H-pyrazol-5-yl)-N-[4-(trifluoromethoxy)phenyl]benzamide;6-(3,6-dihydro-2H-pyran-4-yl)-5-pyrimidin-5-yl-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;6-methyl-5-pyrimidin-5-yl-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;6-(oxan-4-yl)-5-pyrimidin-5-yl-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;5-pyrimidin-5-yl-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide
CID 159909995
6-chloro-N-[4-[chloro(difluoro)methoxy]phenyl]-5-pyrimidin-5-ylpyridine-3-carboxamide;5-(5-fluoro-3-pyridinyl)-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;2-fluoro-5-pyrimidin-5-yl-N-[4-(trifluoromethoxy)phenyl]benzamide;5-pyridin-3-yl-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;6-pyrimidin-5-yl-N-[4-(trifluoromethoxy)phenyl]pyrazine-2-carboxamide;2-pyrimidin-5-yl-N-[4-(trifluoromethoxy)phenyl]pyridine-4-carboxamide;4-pyrimidin-5-yl-N-[4-(trifluoromethoxy)phenyl]pyridine-2-carboxamide;6-pyrimidin-5-yl-N-[4-(trifluoromethoxy)phenyl]pyridine-2-carboxamide
CID 160276110
bis(6-chloro-N-[4-[chloro(difluoro)methoxy]phenyl]-5-(5-fluoro-3-pyridinyl)pyridine-3-carboxamide);6-chloro-5-(1H-pyrazol-5-yl)-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;6-chloro-5-pyridin-3-yl-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;6-chloro-5-pyrimidin-5-yl-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;5-(5-fluoro-3-pyridinyl)-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;2-fluoro-5-pyrimidin-5-yl-N-[4-(trifluoromethoxy)phenyl]benzamide;5-pyridin-3-yl-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;6-pyrimidin-5-yl-N-[4-(trifluoromethoxy)phenyl]pyridine-2-carboxamide
CID 160605296
5-(2-aminopyrimidin-5-yl)-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;6-chloro-5-(1H-imidazol-2-yl)-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;2-fluoro-3-pyrimidin-5-yl-N-[4-(trifluoromethoxy)phenyl]benzamide;5-[1-(2-hydroxyethyl)pyrazol-4-yl]-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;6-(2-hydroxypropan-2-yl)-5-pyrimidin-5-yl-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;2-(2-methoxypyrimidin-5-yl)-N-[4-(trifluoromethoxy)phenyl]pyridine-4-carboxamide
CID 160679059
4-chloro-3-(2-methoxypyrimidin-5-yl)-N-[4-(trifluoromethoxy)phenyl]benzamide;4-chloro-3-pyrimidin-5-yl-N-[4-(trifluoromethoxy)phenyl]benzamide;4-fluoro-3-(2-methoxypyrimidin-5-yl)-N-[4-(trifluoromethoxy)phenyl]benzamide;4-fluoro-3-(1-methylpyrazol-4-yl)-N-[4-(trifluoromethoxy)phenyl]benzamide;4-fluoro-3-(1H-pyrazol-5-yl)-N-[4-(trifluoromethoxy)phenyl]benzamide;4-fluoro-3-pyridin-3-yl-N-[4-(trifluoromethoxy)phenyl]benzamide;4-fluoro-3-pyridin-4-yl-N-[4-(trifluoromethoxy)phenyl]benzamide;4-fluoro-3-pyrimidin-5-yl-N-[4-(trifluoromethoxy)phenyl]benzamide
CID 161040466
5-(2-aminopyrimidin-5-yl)-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;6-chloro-5-(1H-imidazol-2-yl)-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;2-fluoro-3-pyrimidin-5-yl-N-[4-(trifluoromethoxy)phenyl]benzamide;5-[1-(2-hydroxyethyl)pyrazol-4-yl]-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;6-(2-hydroxypropan-2-yl)-5-pyrimidin-5-yl-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;5-(2-methoxy-3-pyridinyl)-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;2-(2-methoxypyrimidin-5-yl)-N-[4-(trifluoromethoxy)phenyl]pyridine-4-carboxamide;5-(2-oxo-1H-pyridin-3-yl)-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide
CID 161574823
4-chloro-3-(2-methoxypyrimidin-5-yl)-N-[4-(trifluoromethoxy)phenyl]benzamide;4-chloro-3-(1-methylpyrazol-4-yl)-N-[4-(trifluoromethoxy)phenyl]benzamide;4-chloro-3-(1H-pyrazol-5-yl)-N-[4-(trifluoromethoxy)phenyl]benzamide;4-chloro-3-pyridin-3-yl-N-[4-(trifluoromethoxy)phenyl]benzamide;4-chloro-3-pyridin-4-yl-N-[4-(trifluoromethoxy)phenyl]benzamide;4-chloro-3-pyrimidin-5-yl-N-[4-(trifluoromethoxy)phenyl]benzamide;6-(3,6-dihydro-2H-pyran-4-yl)-5-pyrimidin-5-yl-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;6-methyl-5-pyrimidin-5-yl-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;5-pyrimidin-5-yl-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide
CID 161927497
6-chloro-N-[4-[chloro(difluoro)methoxy]phenyl]-5-(5-fluoro-3-pyridinyl)pyridine-3-carboxamide;6-chloro-5-(5-fluoro-3-pyridinyl)-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;6-chloro-5-(1H-pyrazol-5-yl)-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;6-chloro-5-pyridin-3-yl-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;6-chloro-5-pyrimidin-5-yl-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;5-(5-fluoro-3-pyridinyl)-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;2-fluoro-5-pyrimidin-5-yl-N-[4-(trifluoromethoxy)phenyl]benzamide;5-pyridin-3-yl-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;6-pyrimidin-5-yl-N-[4-(trifluoromethoxy)phenyl]pyridine-2-carboxamide
CID 161932764
1-(7-chloro-4-methoxy-1H-pyrrolo[2,3-c]pyridin-3-yl)-2-(5-pyridin-3-yl-3,4-dihydro-1H-isoquinolin-2-yl)ethane-1,2-dione;1-[7-[3-(1,1-difluoroethyl)-1,2,4-triazol-1-yl]-4-methoxy-1H-pyrrolo[2,3-c]pyridin-3-yl]-2-(5-pyridin-2-yl-3,4-dihydro-1H-isoquinolin-2-yl)ethane-1,2-dione;1-[7-[3-(hydroxymethyl)pyrazol-1-yl]-4-methoxy-1H-pyrrolo[2,3-c]pyridin-3-yl]-2-(5-pyridin-2-yl-3,4-dihydro-1H-isoquinolin-2-yl)ethane-1,2-dione;1-[7-[4-(hydroxymethyl)pyrazol-1-yl]-4-methoxy-1H-pyrrolo[2,3-c]pyridin-3-yl]-2-(5-pyridin-2-yl-3,4-dihydro-1H-isoquinolin-2-yl)ethane-1,2-dione;1-[4-methoxy-7-[5-(methoxymethyl)-1,2,4-triazol-1-yl]-1H-pyrrolo[2,3-c]pyridin-3-yl]-2-(5-pyridin-2-yl-3,4-dihydro-1H-isoquinolin-2-yl)ethane-1,2-dione;1-[4-methoxy-7-(triazol-1-yl)-1H-pyrrolo[2,3-c]pyridin-3-yl]-2-(4-pyridin-2-yl-6,8-dihydro-5H-pyrido[3,4-d]pyrimidin-7-yl)ethane-1,2-dione
CID 162067410

Frequently Asked Questions

What is the IUPAC name of 5-(2-aminopyrimidin-5-yl)-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;6-chloro-5-(1H-imidazol-2-yl)-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;5-[1-(2-hydroxyethyl)pyrazol-4-yl]-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;6-(2-hydroxypropan-2-yl)-5-pyrimidin-5-yl-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;5-(2-methoxy-3-pyridinyl)-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;2-(2-methoxypyrimidin-5-yl)-N-[4-(trifluoromethoxy)phenyl]pyridine-4-carboxamide;5-(2-oxo-1H-pyridin-3-yl)-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;6-pyrimidin-5-yl-N-[4-(trifluoromethoxy)phenyl]pyrazine-2-carboxamide;2-pyrimidin-5-yl-N-[4-(trifluoromethoxy)phenyl]pyridine-4-carboxamide;4-pyrimidin-5-yl-N-[4-(trifluoromethoxy)phenyl]pyridine-2-carboxamide?
The IUPAC name of 5-(2-aminopyrimidin-5-yl)-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;6-chloro-5-(1H-imidazol-2-yl)-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;5-[1-(2-hydroxyethyl)pyrazol-4-yl]-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;6-(2-hydroxypropan-2-yl)-5-pyrimidin-5-yl-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;5-(2-methoxy-3-pyridinyl)-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;2-(2-methoxypyrimidin-5-yl)-N-[4-(trifluoromethoxy)phenyl]pyridine-4-carboxamide;5-(2-oxo-1H-pyridin-3-yl)-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;6-pyrimidin-5-yl-N-[4-(trifluoromethoxy)phenyl]pyrazine-2-carboxamide;2-pyrimidin-5-yl-N-[4-(trifluoromethoxy)phenyl]pyridine-4-carboxamide;4-pyrimidin-5-yl-N-[4-(trifluoromethoxy)phenyl]pyridine-2-carboxamide (CID 159480833) is 5-(2-aminopyrimidin-5-yl)-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;6-chloro-5-(1H-imidazol-2-yl)-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;5-[1-(2-hydroxyethyl)pyrazol-4-yl]-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;6-(2-hydroxypropan-2-yl)-5-pyrimidin-5-yl-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;5-(2-methoxy-3-pyridinyl)-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;2-(2-methoxypyrimidin-5-yl)-N-[4-(trifluoromethoxy)phenyl]pyridine-4-carboxamide;5-(2-oxo-1H-pyridin-3-yl)-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;6-pyrimidin-5-yl-N-[4-(trifluoromethoxy)phenyl]pyrazine-2-carboxamide;2-pyrimidin-5-yl-N-[4-(trifluoromethoxy)phenyl]pyridine-4-carboxamide;4-pyrimidin-5-yl-N-[4-(trifluoromethoxy)phenyl]pyridine-2-carboxamide.
What is the SMILES notation for 5-(2-aminopyrimidin-5-yl)-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;6-chloro-5-(1H-imidazol-2-yl)-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;5-[1-(2-hydroxyethyl)pyrazol-4-yl]-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;6-(2-hydroxypropan-2-yl)-5-pyrimidin-5-yl-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;5-(2-methoxy-3-pyridinyl)-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;2-(2-methoxypyrimidin-5-yl)-N-[4-(trifluoromethoxy)phenyl]pyridine-4-carboxamide;5-(2-oxo-1H-pyridin-3-yl)-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;6-pyrimidin-5-yl-N-[4-(trifluoromethoxy)phenyl]pyrazine-2-carboxamide;2-pyrimidin-5-yl-N-[4-(trifluoromethoxy)phenyl]pyridine-4-carboxamide;4-pyrimidin-5-yl-N-[4-(trifluoromethoxy)phenyl]pyridine-2-carboxamide?
The canonical SMILES for 5-(2-aminopyrimidin-5-yl)-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;6-chloro-5-(1H-imidazol-2-yl)-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;5-[1-(2-hydroxyethyl)pyrazol-4-yl]-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;6-(2-hydroxypropan-2-yl)-5-pyrimidin-5-yl-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;5-(2-methoxy-3-pyridinyl)-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;2-(2-methoxypyrimidin-5-yl)-N-[4-(trifluoromethoxy)phenyl]pyridine-4-carboxamide;5-(2-oxo-1H-pyridin-3-yl)-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;6-pyrimidin-5-yl-N-[4-(trifluoromethoxy)phenyl]pyrazine-2-carboxamide;2-pyrimidin-5-yl-N-[4-(trifluoromethoxy)phenyl]pyridine-4-carboxamide;4-pyrimidin-5-yl-N-[4-(trifluoromethoxy)phenyl]pyridine-2-carboxamide is CC(C)(O)c1ncc(C(=O)Nc2ccc(OC(F)(F)F)cc2)cc1-c1cncnc1.COc1ncc(-c2cc(C(=O)Nc3ccc(OC(F)(F)F)cc3)ccn2)cn1.COc1ncccc1-c1cncc(C(=O)Nc2ccc(OC(F)(F)F)cc2)c1.Nc1ncc(-c2cncc(C(=O)Nc3ccc(OC(F)(F)F)cc3)c2)cn1.O=C(Nc1ccc(OC(F)(F)F)cc1)c1cc(-c2cncnc2)ccn1.O=C(Nc1ccc(OC(F)(F)F)cc1)c1ccnc(-c2cncnc2)c1.O=C(Nc1ccc(OC(F)(F)F)cc1)c1cnc(Cl)c(-c2ncc[nH]2)c1.O=C(Nc1ccc(OC(F)(F)F)cc1)c1cncc(-c2ccc[nH]c2=O)c1.O=C(Nc1ccc(OC(F)(F)F)cc1)c1cncc(-c2cncnc2)n1.O=C(Nc1ccc(OC(F)(F)F)cc1)c1cncc(-c2cnn(CCO)c2)c1.
What is the InChIKey of 5-(2-aminopyrimidin-5-yl)-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;6-chloro-5-(1H-imidazol-2-yl)-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;5-[1-(2-hydroxyethyl)pyrazol-4-yl]-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;6-(2-hydroxypropan-2-yl)-5-pyrimidin-5-yl-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;5-(2-methoxy-3-pyridinyl)-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;2-(2-methoxypyrimidin-5-yl)-N-[4-(trifluoromethoxy)phenyl]pyridine-4-carboxamide;5-(2-oxo-1H-pyridin-3-yl)-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;6-pyrimidin-5-yl-N-[4-(trifluoromethoxy)phenyl]pyrazine-2-carboxamide;2-pyrimidin-5-yl-N-[4-(trifluoromethoxy)phenyl]pyridine-4-carboxamide;4-pyrimidin-5-yl-N-[4-(trifluoromethoxy)phenyl]pyridine-2-carboxamide?
The InChIKey is LWZDWJBNURMNFD-UHFFFAOYSA-N. The full InChI is InChI=1S/C20H17F3N4O3.C19H14F3N3O3.C18H13F3N4O3.C18H15F3N4O3.C18H12F3N3O3.C17H12F3N5O2.2C17H11F3N4O2.C16H10ClF3N4O2.C16H10F3N5O2/c1-19(2,29)17-16(13-8-24-11-25-9-13)7-12(10-26-17)18(28)27-14-3-5-15(6-4-14)30-20(21,22)23;1-27-18-16(3-2-8-24-18)12-9-13(11-23-10-12)17(26)25-14-4-6-15(7-5-14)28-19(20,21)22;1-27-17-23-9-12(10-24-17)15-8-11(6-7-22-15)16(26)25-13-2-4-14(5-3-13)28-18(19,20)21;19-18(20,21)28-16-3-1-15(2-4-16)24-17(27)13-7-12(8-22-9-13)14-10-23-25(11-14)5-6-26;19-18(20,21)27-14-5-3-13(4-6-14)24-16(25)12-8-11(9-22-10-12)15-2-1-7-23-17(15)26;18-17(19,20)27-14-3-1-13(2-4-14)25-15(26)11-5-10(6-22-7-11)12-8-23-16(21)24-9-12;18-17(19,20)26-14-3-1-13(2-4-14)24-16(25)11-5-6-23-15(7-11)12-8-21-10-22-9-12;18-17(19,20)26-14-3-1-13(2-4-14)24-16(25)15-7-11(5-6-23-15)12-8-21-10-22-9-12;17-13-12(14-21-5-6-22-14)7-9(8-23-13)15(25)24-10-1-3-11(4-2-10)26-16(18,19)20;17-16(18,19)26-12-3-1-11(2-4-12)23-15(25)14-8-20-7-13(24-14)10-5-21-9-22-6-10/h3-11,29H,1-2H3,(H,27,28);2-11H,1H3,(H,25,26);2-10H,1H3,(H,25,26);1-4,7-11,26H,5-6H2,(H,24,27);1-10H,(H,23,26)(H,24,25);1-9H,(H,25,26)(H2,21,23,24);2*1-10H,(H,24,25);1-8H,(H,21,22)(H,24,25);1-9H,(H,23,25).
What are the key properties of 5-(2-aminopyrimidin-5-yl)-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;6-chloro-5-(1H-imidazol-2-yl)-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;5-[1-(2-hydroxyethyl)pyrazol-4-yl]-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;6-(2-hydroxypropan-2-yl)-5-pyrimidin-5-yl-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;5-(2-methoxy-3-pyridinyl)-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;2-(2-methoxypyrimidin-5-yl)-N-[4-(trifluoromethoxy)phenyl]pyridine-4-carboxamide;5-(2-oxo-1H-pyridin-3-yl)-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;6-pyrimidin-5-yl-N-[4-(trifluoromethoxy)phenyl]pyrazine-2-carboxamide;2-pyrimidin-5-yl-N-[4-(trifluoromethoxy)phenyl]pyridine-4-carboxamide;4-pyrimidin-5-yl-N-[4-(trifluoromethoxy)phenyl]pyridine-2-carboxamide?
5-(2-aminopyrimidin-5-yl)-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;6-chloro-5-(1H-imidazol-2-yl)-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;5-[1-(2-hydroxyethyl)pyrazol-4-yl]-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;6-(2-hydroxypropan-2-yl)-5-pyrimidin-5-yl-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;5-(2-methoxy-3-pyridinyl)-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;2-(2-methoxypyrimidin-5-yl)-N-[4-(trifluoromethoxy)phenyl]pyridine-4-carboxamide;5-(2-oxo-1H-pyridin-3-yl)-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;6-pyrimidin-5-yl-N-[4-(trifluoromethoxy)phenyl]pyrazine-2-carboxamide;2-pyrimidin-5-yl-N-[4-(trifluoromethoxy)phenyl]pyridine-4-carboxamide;4-pyrimidin-5-yl-N-[4-(trifluoromethoxy)phenyl]pyridine-2-carboxamide has a molecular weight of 3805.58 g/mol, XLogP of 36.61, 45 rotatable bonds, 15 hydrogen bond donors, and 53 hydrogen bond acceptors.
Where does this data come from?
All data for 5-(2-aminopyrimidin-5-yl)-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;6-chloro-5-(1H-imidazol-2-yl)-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;5-[1-(2-hydroxyethyl)pyrazol-4-yl]-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;6-(2-hydroxypropan-2-yl)-5-pyrimidin-5-yl-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;5-(2-methoxy-3-pyridinyl)-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;2-(2-methoxypyrimidin-5-yl)-N-[4-(trifluoromethoxy)phenyl]pyridine-4-carboxamide;5-(2-oxo-1H-pyridin-3-yl)-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;6-pyrimidin-5-yl-N-[4-(trifluoromethoxy)phenyl]pyrazine-2-carboxamide;2-pyrimidin-5-yl-N-[4-(trifluoromethoxy)phenyl]pyridine-4-carboxamide;4-pyrimidin-5-yl-N-[4-(trifluoromethoxy)phenyl]pyridine-2-carboxamide is sourced from PubChem (CID 159480833), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).