3-benzyl-8-(6-bromo-1H-indazol-4-yl)-1,3,8-triazaspiro[4.5]decane-2,4-dione;N-[2-[4-(6-chloro-1H-indazol-4-yl)piperazin-1-yl]ethyl]methanesulfonamide;1'-(6-chloro-1H-indazol-4-yl)spiro[1,4-dihydroquinoxaline-3,4'-piperidine]-2-one;8-(6-chloro-1H-indazol-4-yl)-3-(2,2,2-trifluoroethyl)-1,3,8-triazaspiro[4.5]decane-2,4-dione

C70H73BrCl3F3N20O7S — CID 159482880

About 3-benzyl-8-(6-bromo-1H-indazol-4-yl)-1,3,8-triazaspiro[4.5]decane-2,4-dione;N-[2-[4-(6-chloro-1H-indazol-4-yl)piperazin-1-yl]ethyl]methanesulfonamide;1'-(6-chloro-1H-indazol-4-yl)spiro[1,4-dihydroquinoxaline-3,4'-piperidine]-2-one;8-(6-chloro-1H-indazol-4-yl)-3-(2,2,2-trifluoroethyl)-1,3,8-triazaspiro[4.5]decane-2,4-dione

3-benzyl-8-(6-bromo-1H-indazol-4-yl)-1,3,8-triazaspiro[4.5]decane-2,4-dione;N-[2-[4-(6-chloro-1H-indazol-4-yl)piperazin-1-yl]ethyl]methanesulfonamide;1'-(6-chloro-1H-indazol-4-yl)spiro[1,4-dihydroquinoxaline-3,4'-piperidine]-2-one;8-(6-chloro-1H-indazol-4-yl)-3-(2,2,2-trifluoroethyl)-1,3,8-triazaspiro[4.5]decane-2,4-dione (PubChem CID 159482880) has the molecular formula C70H73BrCl3F3N20O7S and a molecular weight of 1581.81 g/mol. Its IUPAC name is 3-benzyl-8-(6-bromo-1H-indazol-4-yl)-1,3,8-triazaspiro[4.5]decane-2,4-dione;N-[2-[4-(6-chloro-1H-indazol-4-yl)piperazin-1-yl]ethyl]methanesulfonamide;1'-(6-chloro-1H-indazol-4-yl)spiro[1,4-dihydroquinoxaline-3,4'-piperidine]-2-one;8-(6-chloro-1H-indazol-4-yl)-3-(2,2,2-trifluoroethyl)-1,3,8-triazaspiro[4.5]decane-2,4-dione.

Molecular Properties

• Compound Name: 3-benzyl-8-(6-bromo-1H-indazol-4-yl)-1,3,8-triazaspiro[4.5]decane-2,4-dione;N-[2-[4-(6-chloro-1H-indazol-4-yl)piperazin-1-yl]ethyl]methanesulfonamide;1'-(6-chloro-1H-indazol-4-yl)spiro[1,4-dihydroquinoxaline-3,4'-piperidine]-2-one;8-(6-chloro-1H-indazol-4-yl)-3-(2,2,2-trifluoroethyl)-1,3,8-triazaspiro[4.5]decane-2,4-dione
• PubChem CID: 159482880
• Molecular Formula: C70H73BrCl3F3N20O7S
• Molecular Weight: 1581.81 g/mol
• Exact Mass: 1578.39
• IUPAC Name: 3-benzyl-8-(6-bromo-1H-indazol-4-yl)-1,3,8-triazaspiro[4.5]decane-2,4-dione;N-[2-[4-(6-chloro-1H-indazol-4-yl)piperazin-1-yl]ethyl]methanesulfonamide;1'-(6-chloro-1H-indazol-4-yl)spiro[1,4-dihydroquinoxaline-3,4'-piperidine]-2-one;8-(6-chloro-1H-indazol-4-yl)-3-(2,2,2-trifluoroethyl)-1,3,8-triazaspiro[4.5]decane-2,4-dione
• SMILES: CS(=O)(=O)NCCN1CCN(c2cc(Cl)cc3[nH]ncc23)CC1.O=C1NC2(CCN(c3cc(Br)cc4[nH]ncc34)CC2)C(=O)N1Cc1ccccc1.O=C1NC2(CCN(c3cc(Cl)cc4[nH]ncc34)CC2)C(=O)N1CC(F)(F)F.O=C1Nc2ccccc2NC12CCN(c1cc(Cl)cc3[nH]ncc13)CC2
• InChI: InChI=1S/C21H20BrN5O2.C19H18ClN5O.C16H15ClF3N5O2.C14H20ClN5O2S/c22-15-10-17-16(12-23-25-17)18(11-15)26-8-6-21(7-9-26)19(28)27(20(29)24-21)13-14-4-2-1-3-5-14;20-12-9-16-13(11-21-24-16)17(10-12)25-7-5-19(6-8-25)18(26)22-14-3-1-2-4-15(14)23-19;17-9-5-11-10(7-21-23-11)12(6-9)24-3-1-15(2-4-24)13(26)25(14(27)22-15)8-16(18,19)20;1-23(21,22)17-2-3-19-4-6-20(7-5-19)14-9-11(15)8-13-12(14)10-16-18-13/h1-5,10-12H,6-9,13H2,(H,23,25)(H,24,29);1-4,9-11,23H,5-8H2,(H,21,24)(H,22,26);5-7H,1-4,8H2,(H,21,23)(H,22,27);8-10,17H,2-7H2,1H3,(H,16,18)
• InChIKey: LXFKIADFDURAOI-UHFFFAOYSA-N
• XLogP: 10.59
• TPSA: 317.04 Ų
• H-Bond Donors: 9
• H-Bond Acceptors: 17
• Rotatable Bonds: 11
• Heavy Atoms: 105
• Complexity: —

Lipinski Rule of Five

4 violations

Rule	Value
MW ≤ 500	1581.81
LogP ≤ 5	10.59
H-Bond Donors ≤ 5	9
H-Bond Acceptors ≤ 10	17

Computed Properties (RDKit)

• Structural Alerts: {'alert_name': 'hydantoin', 'substructure': 'N/A'}

Frequently Asked Questions

What is the IUPAC name of 3-benzyl-8-(6-bromo-1H-indazol-4-yl)-1,3,8-triazaspiro[4.5]decane-2,4-dione;N-[2-[4-(6-chloro-1H-indazol-4-yl)piperazin-1-yl]ethyl]methanesulfonamide;1'-(6-chloro-1H-indazol-4-yl)spiro[1,4-dihydroquinoxaline-3,4'-piperidine]-2-one;8-(6-chloro-1H-indazol-4-yl)-3-(2,2,2-trifluoroethyl)-1,3,8-triazaspiro[4.5]decane-2,4-dione?

The IUPAC name of 3-benzyl-8-(6-bromo-1H-indazol-4-yl)-1,3,8-triazaspiro[4.5]decane-2,4-dione;N-[2-[4-(6-chloro-1H-indazol-4-yl)piperazin-1-yl]ethyl]methanesulfonamide;1'-(6-chloro-1H-indazol-4-yl)spiro[1,4-dihydroquinoxaline-3,4'-piperidine]-2-one;8-(6-chloro-1H-indazol-4-yl)-3-(2,2,2-trifluoroethyl)-1,3,8-triazaspiro[4.5]decane-2,4-dione (CID 159482880) is 3-benzyl-8-(6-bromo-1H-indazol-4-yl)-1,3,8-triazaspiro[4.5]decane-2,4-dione;N-[2-[4-(6-chloro-1H-indazol-4-yl)piperazin-1-yl]ethyl]methanesulfonamide;1'-(6-chloro-1H-indazol-4-yl)spiro[1,4-dihydroquinoxaline-3,4'-piperidine]-2-one;8-(6-chloro-1H-indazol-4-yl)-3-(2,2,2-trifluoroethyl)-1,3,8-triazaspiro[4.5]decane-2,4-dione.

What is the SMILES notation for 3-benzyl-8-(6-bromo-1H-indazol-4-yl)-1,3,8-triazaspiro[4.5]decane-2,4-dione;N-[2-[4-(6-chloro-1H-indazol-4-yl)piperazin-1-yl]ethyl]methanesulfonamide;1'-(6-chloro-1H-indazol-4-yl)spiro[1,4-dihydroquinoxaline-3,4'-piperidine]-2-one;8-(6-chloro-1H-indazol-4-yl)-3-(2,2,2-trifluoroethyl)-1,3,8-triazaspiro[4.5]decane-2,4-dione?

The canonical SMILES for 3-benzyl-8-(6-bromo-1H-indazol-4-yl)-1,3,8-triazaspiro[4.5]decane-2,4-dione;N-[2-[4-(6-chloro-1H-indazol-4-yl)piperazin-1-yl]ethyl]methanesulfonamide;1'-(6-chloro-1H-indazol-4-yl)spiro[1,4-dihydroquinoxaline-3,4'-piperidine]-2-one;8-(6-chloro-1H-indazol-4-yl)-3-(2,2,2-trifluoroethyl)-1,3,8-triazaspiro[4.5]decane-2,4-dione is CS(=O)(=O)NCCN1CCN(c2cc(Cl)cc3[nH]ncc23)CC1.O=C1NC2(CCN(c3cc(Br)cc4[nH]ncc34)CC2)C(=O)N1Cc1ccccc1.O=C1NC2(CCN(c3cc(Cl)cc4[nH]ncc34)CC2)C(=O)N1CC(F)(F)F.O=C1Nc2ccccc2NC12CCN(c1cc(Cl)cc3[nH]ncc13)CC2.

What is the InChIKey of 3-benzyl-8-(6-bromo-1H-indazol-4-yl)-1,3,8-triazaspiro[4.5]decane-2,4-dione;N-[2-[4-(6-chloro-1H-indazol-4-yl)piperazin-1-yl]ethyl]methanesulfonamide;1'-(6-chloro-1H-indazol-4-yl)spiro[1,4-dihydroquinoxaline-3,4'-piperidine]-2-one;8-(6-chloro-1H-indazol-4-yl)-3-(2,2,2-trifluoroethyl)-1,3,8-triazaspiro[4.5]decane-2,4-dione?

The InChIKey is LXFKIADFDURAOI-UHFFFAOYSA-N. The full InChI is InChI=1S/C21H20BrN5O2.C19H18ClN5O.C16H15ClF3N5O2.C14H20ClN5O2S/c22-15-10-17-16(12-23-25-17)18(11-15)26-8-6-21(7-9-26)19(28)27(20(29)24-21)13-14-4-2-1-3-5-14;20-12-9-16-13(11-21-24-16)17(10-12)25-7-5-19(6-8-25)18(26)22-14-3-1-2-4-15(14)23-19;17-9-5-11-10(7-21-23-11)12(6-9)24-3-1-15(2-4-24)13(26)25(14(27)22-15)8-16(18,19)20;1-23(21,22)17-2-3-19-4-6-20(7-5-19)14-9-11(15)8-13-12(14)10-16-18-13/h1-5,10-12H,6-9,13H2,(H,23,25)(H,24,29);1-4,9-11,23H,5-8H2,(H,21,24)(H,22,26);5-7H,1-4,8H2,(H,21,23)(H,22,27);8-10,17H,2-7H2,1H3,(H,16,18).

What are the key properties of 3-benzyl-8-(6-bromo-1H-indazol-4-yl)-1,3,8-triazaspiro[4.5]decane-2,4-dione;N-[2-[4-(6-chloro-1H-indazol-4-yl)piperazin-1-yl]ethyl]methanesulfonamide;1'-(6-chloro-1H-indazol-4-yl)spiro[1,4-dihydroquinoxaline-3,4'-piperidine]-2-one;8-(6-chloro-1H-indazol-4-yl)-3-(2,2,2-trifluoroethyl)-1,3,8-triazaspiro[4.5]decane-2,4-dione?

3-benzyl-8-(6-bromo-1H-indazol-4-yl)-1,3,8-triazaspiro[4.5]decane-2,4-dione;N-[2-[4-(6-chloro-1H-indazol-4-yl)piperazin-1-yl]ethyl]methanesulfonamide;1'-(6-chloro-1H-indazol-4-yl)spiro[1,4-dihydroquinoxaline-3,4'-piperidine]-2-one;8-(6-chloro-1H-indazol-4-yl)-3-(2,2,2-trifluoroethyl)-1,3,8-triazaspiro[4.5]decane-2,4-dione has a molecular weight of 1581.81 g/mol, XLogP of 10.59, 11 rotatable bonds, 9 hydrogen bond donors, and 17 hydrogen bond acceptors.

Where does this data come from?

All data for 3-benzyl-8-(6-bromo-1H-indazol-4-yl)-1,3,8-triazaspiro[4.5]decane-2,4-dione;N-[2-[4-(6-chloro-1H-indazol-4-yl)piperazin-1-yl]ethyl]methanesulfonamide;1'-(6-chloro-1H-indazol-4-yl)spiro[1,4-dihydroquinoxaline-3,4'-piperidine]-2-one;8-(6-chloro-1H-indazol-4-yl)-3-(2,2,2-trifluoroethyl)-1,3,8-triazaspiro[4.5]decane-2,4-dione is sourced from PubChem (CID 159482880), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).