N-tert-butyl-4-ethyl-2-(1,2-thiazol-5-yl)imidazo[1,5-a]pyrimidine-8-carboxamide;N-tert-butyl-2-(2-fluoro-5-methoxyphenyl)-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;N-(1-cyclopropyl-2,2-difluoropropyl)-4-ethyl-2-(1,2-thiazol-3-yl)imidazo[1,5-a]pyrimidine-8-carboxamide;N-[(1S)-1-cyclopropylethyl]-4-methyl-2-[6-(trifluoromethoxy)-2-pyridinyl]imidazo[1,5-a]pyrimidine-8-carboxamide;N-(1-cyclopropyl-2,2,2-trifluoroethyl)-2-(6-ethoxy-2-pyridinyl)-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;N-(1-cyclopropyl-2,2,2-trifluoroethyl)-4-methyl-2-(2-phenylacetyl)imidazo[1,5-a]pyrimidine-8-carboxamide;2-(2-fluoro-5-methoxyphenyl)-4-methyl-N-propan-2-ylimidazo[1,5-a]pyrimidine-8-carboxamide

C131H135F13N32O12S2 — CID 159483355

About N-tert-butyl-4-ethyl-2-(1,2-thiazol-5-yl)imidazo[1,5-a]pyrimidine-8-carboxamide;N-tert-butyl-2-(2-fluoro-5-methoxyphenyl)-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;N-(1-cyclopropyl-2,2-difluoropropyl)-4-ethyl-2-(1,2-thiazol-3-yl)imidazo[1,5-a]pyrimidine-8-carboxamide;N-[(1S)-1-cyclopropylethyl]-4-methyl-2-[6-(trifluoromethoxy)-2-pyridinyl]imidazo[1,5-a]pyrimidine-8-carboxamide;N-(1-cyclopropyl-2,2,2-trifluoroethyl)-2-(6-ethoxy-2-pyridinyl)-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;N-(1-cyclopropyl-2,2,2-trifluoroethyl)-4-methyl-2-(2-phenylacetyl)imidazo[1,5-a]pyrimidine-8-carboxamide;2-(2-fluoro-5-methoxyphenyl)-4-methyl-N-propan-2-ylimidazo[1,5-a]pyrimidine-8-carboxamide

N-tert-butyl-4-ethyl-2-(1,2-thiazol-5-yl)imidazo[1,5-a]pyrimidine-8-carboxamide;N-tert-butyl-2-(2-fluoro-5-methoxyphenyl)-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;N-(1-cyclopropyl-2,2-difluoropropyl)-4-ethyl-2-(1,2-thiazol-3-yl)imidazo[1,5-a]pyrimidine-8-carboxamide;N-[(1S)-1-cyclopropylethyl]-4-methyl-2-[6-(trifluoromethoxy)-2-pyridinyl]imidazo[1,5-a]pyrimidine-8-carboxamide;N-(1-cyclopropyl-2,2,2-trifluoroethyl)-2-(6-ethoxy-2-pyridinyl)-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;N-(1-cyclopropyl-2,2,2-trifluoroethyl)-4-methyl-2-(2-phenylacetyl)imidazo[1,5-a]pyrimidine-8-carboxamide;2-(2-fluoro-5-methoxyphenyl)-4-methyl-N-propan-2-ylimidazo[1,5-a]pyrimidine-8-carboxamide (PubChem CID 159483355) has the molecular formula C131H135F13N32O12S2 and a molecular weight of 2660.84 g/mol. Its IUPAC name is N-tert-butyl-4-ethyl-2-(1,2-thiazol-5-yl)imidazo[1,5-a]pyrimidine-8-carboxamide;N-tert-butyl-2-(2-fluoro-5-methoxyphenyl)-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;N-(1-cyclopropyl-2,2-difluoropropyl)-4-ethyl-2-(1,2-thiazol-3-yl)imidazo[1,5-a]pyrimidine-8-carboxamide;N-[(1S)-1-cyclopropylethyl]-4-methyl-2-[6-(trifluoromethoxy)-2-pyridinyl]imidazo[1,5-a]pyrimidine-8-carboxamide;N-(1-cyclopropyl-2,2,2-trifluoroethyl)-2-(6-ethoxy-2-pyridinyl)-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;N-(1-cyclopropyl-2,2,2-trifluoroethyl)-4-methyl-2-(2-phenylacetyl)imidazo[1,5-a]pyrimidine-8-carboxamide;2-(2-fluoro-5-methoxyphenyl)-4-methyl-N-propan-2-ylimidazo[1,5-a]pyrimidine-8-carboxamide.

Molecular Properties

• Compound Name: N-tert-butyl-4-ethyl-2-(1,2-thiazol-5-yl)imidazo[1,5-a]pyrimidine-8-carboxamide;N-tert-butyl-2-(2-fluoro-5-methoxyphenyl)-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;N-(1-cyclopropyl-2,2-difluoropropyl)-4-ethyl-2-(1,2-thiazol-3-yl)imidazo[1,5-a]pyrimidine-8-carboxamide;N-[(1S)-1-cyclopropylethyl]-4-methyl-2-[6-(trifluoromethoxy)-2-pyridinyl]imidazo[1,5-a]pyrimidine-8-carboxamide;N-(1-cyclopropyl-2,2,2-trifluoroethyl)-2-(6-ethoxy-2-pyridinyl)-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;N-(1-cyclopropyl-2,2,2-trifluoroethyl)-4-methyl-2-(2-phenylacetyl)imidazo[1,5-a]pyrimidine-8-carboxamide;2-(2-fluoro-5-methoxyphenyl)-4-methyl-N-propan-2-ylimidazo[1,5-a]pyrimidine-8-carboxamide
• PubChem CID: 159483355
• Molecular Formula: C131H135F13N32O12S2
• Molecular Weight: 2660.84 g/mol
• Exact Mass: 2659.02
• IUPAC Name: N-tert-butyl-4-ethyl-2-(1,2-thiazol-5-yl)imidazo[1,5-a]pyrimidine-8-carboxamide;N-tert-butyl-2-(2-fluoro-5-methoxyphenyl)-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;N-(1-cyclopropyl-2,2-difluoropropyl)-4-ethyl-2-(1,2-thiazol-3-yl)imidazo[1,5-a]pyrimidine-8-carboxamide;N-[(1S)-1-cyclopropylethyl]-4-methyl-2-[6-(trifluoromethoxy)-2-pyridinyl]imidazo[1,5-a]pyrimidine-8-carboxamide;N-(1-cyclopropyl-2,2,2-trifluoroethyl)-2-(6-ethoxy-2-pyridinyl)-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;N-(1-cyclopropyl-2,2,2-trifluoroethyl)-4-methyl-2-(2-phenylacetyl)imidazo[1,5-a]pyrimidine-8-carboxamide;2-(2-fluoro-5-methoxyphenyl)-4-methyl-N-propan-2-ylimidazo[1,5-a]pyrimidine-8-carboxamide
• SMILES: CCOc1cccc(-c2cc(C)n3cnc(C(=O)NC(C4CC4)C(F)(F)F)c3n2)n1.CCc1cc(-c2ccns2)nc2c(C(=O)NC(C)(C)C)ncn12.CCc1cc(-c2ccsn2)nc2c(C(=O)NC(C3CC3)C(C)(F)F)ncn12.COc1ccc(F)c(-c2cc(C)n3cnc(C(=O)NC(C)(C)C)c3n2)c1.COc1ccc(F)c(-c2cc(C)n3cnc(C(=O)NC(C)C)c3n2)c1.Cc1cc(-c2cccc(OC(F)(F)F)n2)nc2c(C(=O)N[C@@H](C)C3CC3)ncn12.Cc1cc(C(=O)Cc2ccccc2)nc2c(C(=O)NC(C3CC3)C(F)(F)F)ncn12
• InChI: InChI=1S/C21H19F3N4O2.C20H20F3N5O2.C19H18F3N5O2.C19H21FN4O2.C18H19F2N5OS.C18H19FN4O2.C16H19N5OS/c1-12-9-15(16(29)10-13-5-3-2-4-6-13)26-19-17(25-11-28(12)19)20(30)27-18(14-7-8-14)21(22,23)24;1-3-30-15-6-4-5-13(25-15)14-9-11(2)28-10-24-16(18(28)26-14)19(29)27-17(12-7-8-12)20(21,22)23;1-10-8-14(13-4-3-5-15(25-13)29-19(20,21)22)26-17-16(23-9-27(10)17)18(28)24-11(2)12-6-7-12;1-11-8-15(13-9-12(26-5)6-7-14(13)20)22-17-16(21-10-24(11)17)18(25)23-19(2,3)4;1-3-11-8-13(12-6-7-27-24-12)22-16-14(21-9-25(11)16)17(26)23-15(10-4-5-10)18(2,19)20;1-10(2)21-18(24)16-17-22-15(7-11(3)23(17)9-20-16)13-8-12(25-4)5-6-14(13)19;1-5-10-8-11(12-6-7-18-23-12)19-14-13(17-9-21(10)14)15(22)20-16(2,3)4/h2-6,9,11,14,18H,7-8,10H2,1H3,(H,27,30);4-6,9-10,12,17H,3,7-8H2,1-2H3,(H,27,29);3-5,8-9,11-12H,6-7H2,1-2H3,(H,24,28);6-10H,1-5H3,(H,23,25);6-10,15H,3-5H2,1-2H3,(H,23,26);5-10H,1-4H3,(H,21,24);6-9H,5H2,1-4H3,(H,20,22)/t;;11-;;;;/m..0..../s1
• InChIKey: LXGVTKPASLPQPD-CHKIJZOGSA-N
• XLogP: 23.52
• TPSA: 520.58 Ų
• H-Bond Donors: 7
• H-Bond Acceptors: 39
• Rotatable Bonds: 33
• Heavy Atoms: 190
• Complexity: —

Lipinski Rule of Five

4 violations

Rule	Value
MW ≤ 500	2660.84
LogP ≤ 5	23.52
H-Bond Donors ≤ 5	7
H-Bond Acceptors ≤ 10	39

Frequently Asked Questions

What is the IUPAC name of N-tert-butyl-4-ethyl-2-(1,2-thiazol-5-yl)imidazo[1,5-a]pyrimidine-8-carboxamide;N-tert-butyl-2-(2-fluoro-5-methoxyphenyl)-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;N-(1-cyclopropyl-2,2-difluoropropyl)-4-ethyl-2-(1,2-thiazol-3-yl)imidazo[1,5-a]pyrimidine-8-carboxamide;N-[(1S)-1-cyclopropylethyl]-4-methyl-2-[6-(trifluoromethoxy)-2-pyridinyl]imidazo[1,5-a]pyrimidine-8-carboxamide;N-(1-cyclopropyl-2,2,2-trifluoroethyl)-2-(6-ethoxy-2-pyridinyl)-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;N-(1-cyclopropyl-2,2,2-trifluoroethyl)-4-methyl-2-(2-phenylacetyl)imidazo[1,5-a]pyrimidine-8-carboxamide;2-(2-fluoro-5-methoxyphenyl)-4-methyl-N-propan-2-ylimidazo[1,5-a]pyrimidine-8-carboxamide?

The IUPAC name of N-tert-butyl-4-ethyl-2-(1,2-thiazol-5-yl)imidazo[1,5-a]pyrimidine-8-carboxamide;N-tert-butyl-2-(2-fluoro-5-methoxyphenyl)-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;N-(1-cyclopropyl-2,2-difluoropropyl)-4-ethyl-2-(1,2-thiazol-3-yl)imidazo[1,5-a]pyrimidine-8-carboxamide;N-[(1S)-1-cyclopropylethyl]-4-methyl-2-[6-(trifluoromethoxy)-2-pyridinyl]imidazo[1,5-a]pyrimidine-8-carboxamide;N-(1-cyclopropyl-2,2,2-trifluoroethyl)-2-(6-ethoxy-2-pyridinyl)-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;N-(1-cyclopropyl-2,2,2-trifluoroethyl)-4-methyl-2-(2-phenylacetyl)imidazo[1,5-a]pyrimidine-8-carboxamide;2-(2-fluoro-5-methoxyphenyl)-4-methyl-N-propan-2-ylimidazo[1,5-a]pyrimidine-8-carboxamide (CID 159483355) is N-tert-butyl-4-ethyl-2-(1,2-thiazol-5-yl)imidazo[1,5-a]pyrimidine-8-carboxamide;N-tert-butyl-2-(2-fluoro-5-methoxyphenyl)-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;N-(1-cyclopropyl-2,2-difluoropropyl)-4-ethyl-2-(1,2-thiazol-3-yl)imidazo[1,5-a]pyrimidine-8-carboxamide;N-[(1S)-1-cyclopropylethyl]-4-methyl-2-[6-(trifluoromethoxy)-2-pyridinyl]imidazo[1,5-a]pyrimidine-8-carboxamide;N-(1-cyclopropyl-2,2,2-trifluoroethyl)-2-(6-ethoxy-2-pyridinyl)-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;N-(1-cyclopropyl-2,2,2-trifluoroethyl)-4-methyl-2-(2-phenylacetyl)imidazo[1,5-a]pyrimidine-8-carboxamide;2-(2-fluoro-5-methoxyphenyl)-4-methyl-N-propan-2-ylimidazo[1,5-a]pyrimidine-8-carboxamide.

What is the SMILES notation for N-tert-butyl-4-ethyl-2-(1,2-thiazol-5-yl)imidazo[1,5-a]pyrimidine-8-carboxamide;N-tert-butyl-2-(2-fluoro-5-methoxyphenyl)-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;N-(1-cyclopropyl-2,2-difluoropropyl)-4-ethyl-2-(1,2-thiazol-3-yl)imidazo[1,5-a]pyrimidine-8-carboxamide;N-[(1S)-1-cyclopropylethyl]-4-methyl-2-[6-(trifluoromethoxy)-2-pyridinyl]imidazo[1,5-a]pyrimidine-8-carboxamide;N-(1-cyclopropyl-2,2,2-trifluoroethyl)-2-(6-ethoxy-2-pyridinyl)-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;N-(1-cyclopropyl-2,2,2-trifluoroethyl)-4-methyl-2-(2-phenylacetyl)imidazo[1,5-a]pyrimidine-8-carboxamide;2-(2-fluoro-5-methoxyphenyl)-4-methyl-N-propan-2-ylimidazo[1,5-a]pyrimidine-8-carboxamide?

The canonical SMILES for N-tert-butyl-4-ethyl-2-(1,2-thiazol-5-yl)imidazo[1,5-a]pyrimidine-8-carboxamide;N-tert-butyl-2-(2-fluoro-5-methoxyphenyl)-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;N-(1-cyclopropyl-2,2-difluoropropyl)-4-ethyl-2-(1,2-thiazol-3-yl)imidazo[1,5-a]pyrimidine-8-carboxamide;N-[(1S)-1-cyclopropylethyl]-4-methyl-2-[6-(trifluoromethoxy)-2-pyridinyl]imidazo[1,5-a]pyrimidine-8-carboxamide;N-(1-cyclopropyl-2,2,2-trifluoroethyl)-2-(6-ethoxy-2-pyridinyl)-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;N-(1-cyclopropyl-2,2,2-trifluoroethyl)-4-methyl-2-(2-phenylacetyl)imidazo[1,5-a]pyrimidine-8-carboxamide;2-(2-fluoro-5-methoxyphenyl)-4-methyl-N-propan-2-ylimidazo[1,5-a]pyrimidine-8-carboxamide is CCOc1cccc(-c2cc(C)n3cnc(C(=O)NC(C4CC4)C(F)(F)F)c3n2)n1.CCc1cc(-c2ccns2)nc2c(C(=O)NC(C)(C)C)ncn12.CCc1cc(-c2ccsn2)nc2c(C(=O)NC(C3CC3)C(C)(F)F)ncn12.COc1ccc(F)c(-c2cc(C)n3cnc(C(=O)NC(C)(C)C)c3n2)c1.COc1ccc(F)c(-c2cc(C)n3cnc(C(=O)NC(C)C)c3n2)c1.Cc1cc(-c2cccc(OC(F)(F)F)n2)nc2c(C(=O)N[C@@H](C)C3CC3)ncn12.Cc1cc(C(=O)Cc2ccccc2)nc2c(C(=O)NC(C3CC3)C(F)(F)F)ncn12.

What is the InChIKey of N-tert-butyl-4-ethyl-2-(1,2-thiazol-5-yl)imidazo[1,5-a]pyrimidine-8-carboxamide;N-tert-butyl-2-(2-fluoro-5-methoxyphenyl)-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;N-(1-cyclopropyl-2,2-difluoropropyl)-4-ethyl-2-(1,2-thiazol-3-yl)imidazo[1,5-a]pyrimidine-8-carboxamide;N-[(1S)-1-cyclopropylethyl]-4-methyl-2-[6-(trifluoromethoxy)-2-pyridinyl]imidazo[1,5-a]pyrimidine-8-carboxamide;N-(1-cyclopropyl-2,2,2-trifluoroethyl)-2-(6-ethoxy-2-pyridinyl)-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;N-(1-cyclopropyl-2,2,2-trifluoroethyl)-4-methyl-2-(2-phenylacetyl)imidazo[1,5-a]pyrimidine-8-carboxamide;2-(2-fluoro-5-methoxyphenyl)-4-methyl-N-propan-2-ylimidazo[1,5-a]pyrimidine-8-carboxamide?

The InChIKey is LXGVTKPASLPQPD-CHKIJZOGSA-N. The full InChI is InChI=1S/C21H19F3N4O2.C20H20F3N5O2.C19H18F3N5O2.C19H21FN4O2.C18H19F2N5OS.C18H19FN4O2.C16H19N5OS/c1-12-9-15(16(29)10-13-5-3-2-4-6-13)26-19-17(25-11-28(12)19)20(30)27-18(14-7-8-14)21(22,23)24;1-3-30-15-6-4-5-13(25-15)14-9-11(2)28-10-24-16(18(28)26-14)19(29)27-17(12-7-8-12)20(21,22)23;1-10-8-14(13-4-3-5-15(25-13)29-19(20,21)22)26-17-16(23-9-27(10)17)18(28)24-11(2)12-6-7-12;1-11-8-15(13-9-12(26-5)6-7-14(13)20)22-17-16(21-10-24(11)17)18(25)23-19(2,3)4;1-3-11-8-13(12-6-7-27-24-12)22-16-14(21-9-25(11)16)17(26)23-15(10-4-5-10)18(2,19)20;1-10(2)21-18(24)16-17-22-15(7-11(3)23(17)9-20-16)13-8-12(25-4)5-6-14(13)19;1-5-10-8-11(12-6-7-18-23-12)19-14-13(17-9-21(10)14)15(22)20-16(2,3)4/h2-6,9,11,14,18H,7-8,10H2,1H3,(H,27,30);4-6,9-10,12,17H,3,7-8H2,1-2H3,(H,27,29);3-5,8-9,11-12H,6-7H2,1-2H3,(H,24,28);6-10H,1-5H3,(H,23,25);6-10,15H,3-5H2,1-2H3,(H,23,26);5-10H,1-4H3,(H,21,24);6-9H,5H2,1-4H3,(H,20,22)/t;;11-;;;;/m..0..../s1.

What are the key properties of N-tert-butyl-4-ethyl-2-(1,2-thiazol-5-yl)imidazo[1,5-a]pyrimidine-8-carboxamide;N-tert-butyl-2-(2-fluoro-5-methoxyphenyl)-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;N-(1-cyclopropyl-2,2-difluoropropyl)-4-ethyl-2-(1,2-thiazol-3-yl)imidazo[1,5-a]pyrimidine-8-carboxamide;N-[(1S)-1-cyclopropylethyl]-4-methyl-2-[6-(trifluoromethoxy)-2-pyridinyl]imidazo[1,5-a]pyrimidine-8-carboxamide;N-(1-cyclopropyl-2,2,2-trifluoroethyl)-2-(6-ethoxy-2-pyridinyl)-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;N-(1-cyclopropyl-2,2,2-trifluoroethyl)-4-methyl-2-(2-phenylacetyl)imidazo[1,5-a]pyrimidine-8-carboxamide;2-(2-fluoro-5-methoxyphenyl)-4-methyl-N-propan-2-ylimidazo[1,5-a]pyrimidine-8-carboxamide?

N-tert-butyl-4-ethyl-2-(1,2-thiazol-5-yl)imidazo[1,5-a]pyrimidine-8-carboxamide;N-tert-butyl-2-(2-fluoro-5-methoxyphenyl)-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;N-(1-cyclopropyl-2,2-difluoropropyl)-4-ethyl-2-(1,2-thiazol-3-yl)imidazo[1,5-a]pyrimidine-8-carboxamide;N-[(1S)-1-cyclopropylethyl]-4-methyl-2-[6-(trifluoromethoxy)-2-pyridinyl]imidazo[1,5-a]pyrimidine-8-carboxamide;N-(1-cyclopropyl-2,2,2-trifluoroethyl)-2-(6-ethoxy-2-pyridinyl)-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;N-(1-cyclopropyl-2,2,2-trifluoroethyl)-4-methyl-2-(2-phenylacetyl)imidazo[1,5-a]pyrimidine-8-carboxamide;2-(2-fluoro-5-methoxyphenyl)-4-methyl-N-propan-2-ylimidazo[1,5-a]pyrimidine-8-carboxamide has a molecular weight of 2660.84 g/mol, XLogP of 23.52, 33 rotatable bonds, 7 hydrogen bond donors, and 39 hydrogen bond acceptors.

Where does this data come from?

All data for N-tert-butyl-4-ethyl-2-(1,2-thiazol-5-yl)imidazo[1,5-a]pyrimidine-8-carboxamide;N-tert-butyl-2-(2-fluoro-5-methoxyphenyl)-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;N-(1-cyclopropyl-2,2-difluoropropyl)-4-ethyl-2-(1,2-thiazol-3-yl)imidazo[1,5-a]pyrimidine-8-carboxamide;N-[(1S)-1-cyclopropylethyl]-4-methyl-2-[6-(trifluoromethoxy)-2-pyridinyl]imidazo[1,5-a]pyrimidine-8-carboxamide;N-(1-cyclopropyl-2,2,2-trifluoroethyl)-2-(6-ethoxy-2-pyridinyl)-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;N-(1-cyclopropyl-2,2,2-trifluoroethyl)-4-methyl-2-(2-phenylacetyl)imidazo[1,5-a]pyrimidine-8-carboxamide;2-(2-fluoro-5-methoxyphenyl)-4-methyl-N-propan-2-ylimidazo[1,5-a]pyrimidine-8-carboxamide is sourced from PubChem (CID 159483355), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).