1-N'-[6-fluoro-3-[(E)-2-(4-fluorophenyl)ethenyl]-1H-indazol-5-yl]cyclopropane-1,1-dicarboxamide;N-[6-fluoro-3-[(E)-2-(4-fluorophenyl)ethenyl]-1H-indazol-5-yl]-3-hydroxybutanamide;(3R)-N-[6-fluoro-3-[(E)-2-(4-fluorophenyl)ethenyl]-1H-indazol-5-yl]-3-hydroxy-3-phenylpropanamide;N-[6-fluoro-3-[(E)-2-pyridin-3-ylethenyl]-1H-indazol-5-yl]-3-hydroxy-2,2-dimethylpropanamide;N-[6-fluoro-3-[(E)-2-pyridin-3-ylethenyl]-1H-indazol-5-yl]-3-hydroxy-3-methylbutanamide

C101H90F8N18O10 — CID 159492171

About 1-N'-[6-fluoro-3-[(E)-2-(4-fluorophenyl)ethenyl]-1H-indazol-5-yl]cyclopropane-1,1-dicarboxamide;N-[6-fluoro-3-[(E)-2-(4-fluorophenyl)ethenyl]-1H-indazol-5-yl]-3-hydroxybutanamide;(3R)-N-[6-fluoro-3-[(E)-2-(4-fluorophenyl)ethenyl]-1H-indazol-5-yl]-3-hydroxy-3-phenylpropanamide;N-[6-fluoro-3-[(E)-2-pyridin-3-ylethenyl]-1H-indazol-5-yl]-3-hydroxy-2,2-dimethylpropanamide;N-[6-fluoro-3-[(E)-2-pyridin-3-ylethenyl]-1H-indazol-5-yl]-3-hydroxy-3-methylbutanamide

1-N'-[6-fluoro-3-[(E)-2-(4-fluorophenyl)ethenyl]-1H-indazol-5-yl]cyclopropane-1,1-dicarboxamide;N-[6-fluoro-3-[(E)-2-(4-fluorophenyl)ethenyl]-1H-indazol-5-yl]-3-hydroxybutanamide;(3R)-N-[6-fluoro-3-[(E)-2-(4-fluorophenyl)ethenyl]-1H-indazol-5-yl]-3-hydroxy-3-phenylpropanamide;N-[6-fluoro-3-[(E)-2-pyridin-3-ylethenyl]-1H-indazol-5-yl]-3-hydroxy-2,2-dimethylpropanamide;N-[6-fluoro-3-[(E)-2-pyridin-3-ylethenyl]-1H-indazol-5-yl]-3-hydroxy-3-methylbutanamide (PubChem CID 159492171) has the molecular formula C101H90F8N18O10 and a molecular weight of 1867.93 g/mol. Its IUPAC name is 1-N'-[6-fluoro-3-[(E)-2-(4-fluorophenyl)ethenyl]-1H-indazol-5-yl]cyclopropane-1,1-dicarboxamide;N-[6-fluoro-3-[(E)-2-(4-fluorophenyl)ethenyl]-1H-indazol-5-yl]-3-hydroxybutanamide;(3R)-N-[6-fluoro-3-[(E)-2-(4-fluorophenyl)ethenyl]-1H-indazol-5-yl]-3-hydroxy-3-phenylpropanamide;N-[6-fluoro-3-[(E)-2-pyridin-3-ylethenyl]-1H-indazol-5-yl]-3-hydroxy-2,2-dimethylpropanamide;N-[6-fluoro-3-[(E)-2-pyridin-3-ylethenyl]-1H-indazol-5-yl]-3-hydroxy-3-methylbutanamide.

Molecular Properties

• Compound Name: 1-N'-[6-fluoro-3-[(E)-2-(4-fluorophenyl)ethenyl]-1H-indazol-5-yl]cyclopropane-1,1-dicarboxamide;N-[6-fluoro-3-[(E)-2-(4-fluorophenyl)ethenyl]-1H-indazol-5-yl]-3-hydroxybutanamide;(3R)-N-[6-fluoro-3-[(E)-2-(4-fluorophenyl)ethenyl]-1H-indazol-5-yl]-3-hydroxy-3-phenylpropanamide;N-[6-fluoro-3-[(E)-2-pyridin-3-ylethenyl]-1H-indazol-5-yl]-3-hydroxy-2,2-dimethylpropanamide;N-[6-fluoro-3-[(E)-2-pyridin-3-ylethenyl]-1H-indazol-5-yl]-3-hydroxy-3-methylbutanamide
• PubChem CID: 159492171
• Molecular Formula: C101H90F8N18O10
• Molecular Weight: 1867.93 g/mol
• Exact Mass: 1866.70
• IUPAC Name: 1-N'-[6-fluoro-3-[(E)-2-(4-fluorophenyl)ethenyl]-1H-indazol-5-yl]cyclopropane-1,1-dicarboxamide;N-[6-fluoro-3-[(E)-2-(4-fluorophenyl)ethenyl]-1H-indazol-5-yl]-3-hydroxybutanamide;(3R)-N-[6-fluoro-3-[(E)-2-(4-fluorophenyl)ethenyl]-1H-indazol-5-yl]-3-hydroxy-3-phenylpropanamide;N-[6-fluoro-3-[(E)-2-pyridin-3-ylethenyl]-1H-indazol-5-yl]-3-hydroxy-2,2-dimethylpropanamide;N-[6-fluoro-3-[(E)-2-pyridin-3-ylethenyl]-1H-indazol-5-yl]-3-hydroxy-3-methylbutanamide
• SMILES: CC(C)(CO)C(=O)Nc1cc2c(/C=C/c3cccnc3)n[nH]c2cc1F.CC(C)(O)CC(=O)Nc1cc2c(/C=C/c3cccnc3)n[nH]c2cc1F.CC(O)CC(=O)Nc1cc2c(/C=C/c3ccc(F)cc3)n[nH]c2cc1F.NC(=O)C1(C(=O)Nc2cc3c(/C=C/c4ccc(F)cc4)n[nH]c3cc2F)CC1.O=C(C[C@@H](O)c1ccccc1)Nc1cc2c(/C=C/c3ccc(F)cc3)n[nH]c2cc1F
• InChI: InChI=1S/C24H19F2N3O2.C20H16F2N4O2.C19H17F2N3O2.2C19H19FN4O2/c25-17-9-6-15(7-10-17)8-11-20-18-12-22(19(26)13-21(18)29-28-20)27-24(31)14-23(30)16-4-2-1-3-5-16;21-12-4-1-11(2-5-12)3-6-15-13-9-17(14(22)10-16(13)26-25-15)24-19(28)20(7-8-20)18(23)27;1-11(25)8-19(26)22-18-9-14-16(23-24-17(14)10-15(18)21)7-4-12-2-5-13(20)6-3-12;1-19(2,26)10-18(25)22-17-8-13-15(23-24-16(13)9-14(17)20)6-5-12-4-3-7-21-11-12;1-19(2,11-25)18(26)22-17-8-13-15(23-24-16(13)9-14(17)20)6-5-12-4-3-7-21-10-12/h1-13,23,30H,14H2,(H,27,31)(H,28,29);1-6,9-10H,7-8H2,(H2,23,27)(H,24,28)(H,25,26);2-7,9-11,25H,8H2,1H3,(H,22,26)(H,23,24);3-9,11,26H,10H2,1-2H3,(H,22,25)(H,23,24);3-10,25H,11H2,1-2H3,(H,22,26)(H,23,24)/b11-8+;6-3+;7-4+;2*6-5+/t23-;;;;/m1..../s1
• InChIKey: LYIFZWOWDOWZHB-SPYRSNAPSA-N
• XLogP: 18.60
• TPSA: 438.69 Ų
• H-Bond Donors: 15
• H-Bond Acceptors: 17
• Rotatable Bonds: 26
• Heavy Atoms: 137
• Complexity: —

Lipinski Rule of Five

4 violations

Rule	Value
MW ≤ 500	1867.93
LogP ≤ 5	18.60
H-Bond Donors ≤ 5	15
H-Bond Acceptors ≤ 10	17

Computed Properties (RDKit)

• Structural Alerts: {'alert_name': 'beta-keto/anhydride', 'substructure': 'N/A'}

Frequently Asked Questions

What is the IUPAC name of 1-N'-[6-fluoro-3-[(E)-2-(4-fluorophenyl)ethenyl]-1H-indazol-5-yl]cyclopropane-1,1-dicarboxamide;N-[6-fluoro-3-[(E)-2-(4-fluorophenyl)ethenyl]-1H-indazol-5-yl]-3-hydroxybutanamide;(3R)-N-[6-fluoro-3-[(E)-2-(4-fluorophenyl)ethenyl]-1H-indazol-5-yl]-3-hydroxy-3-phenylpropanamide;N-[6-fluoro-3-[(E)-2-pyridin-3-ylethenyl]-1H-indazol-5-yl]-3-hydroxy-2,2-dimethylpropanamide;N-[6-fluoro-3-[(E)-2-pyridin-3-ylethenyl]-1H-indazol-5-yl]-3-hydroxy-3-methylbutanamide?

The IUPAC name of 1-N'-[6-fluoro-3-[(E)-2-(4-fluorophenyl)ethenyl]-1H-indazol-5-yl]cyclopropane-1,1-dicarboxamide;N-[6-fluoro-3-[(E)-2-(4-fluorophenyl)ethenyl]-1H-indazol-5-yl]-3-hydroxybutanamide;(3R)-N-[6-fluoro-3-[(E)-2-(4-fluorophenyl)ethenyl]-1H-indazol-5-yl]-3-hydroxy-3-phenylpropanamide;N-[6-fluoro-3-[(E)-2-pyridin-3-ylethenyl]-1H-indazol-5-yl]-3-hydroxy-2,2-dimethylpropanamide;N-[6-fluoro-3-[(E)-2-pyridin-3-ylethenyl]-1H-indazol-5-yl]-3-hydroxy-3-methylbutanamide (CID 159492171) is 1-N'-[6-fluoro-3-[(E)-2-(4-fluorophenyl)ethenyl]-1H-indazol-5-yl]cyclopropane-1,1-dicarboxamide;N-[6-fluoro-3-[(E)-2-(4-fluorophenyl)ethenyl]-1H-indazol-5-yl]-3-hydroxybutanamide;(3R)-N-[6-fluoro-3-[(E)-2-(4-fluorophenyl)ethenyl]-1H-indazol-5-yl]-3-hydroxy-3-phenylpropanamide;N-[6-fluoro-3-[(E)-2-pyridin-3-ylethenyl]-1H-indazol-5-yl]-3-hydroxy-2,2-dimethylpropanamide;N-[6-fluoro-3-[(E)-2-pyridin-3-ylethenyl]-1H-indazol-5-yl]-3-hydroxy-3-methylbutanamide.

What is the SMILES notation for 1-N'-[6-fluoro-3-[(E)-2-(4-fluorophenyl)ethenyl]-1H-indazol-5-yl]cyclopropane-1,1-dicarboxamide;N-[6-fluoro-3-[(E)-2-(4-fluorophenyl)ethenyl]-1H-indazol-5-yl]-3-hydroxybutanamide;(3R)-N-[6-fluoro-3-[(E)-2-(4-fluorophenyl)ethenyl]-1H-indazol-5-yl]-3-hydroxy-3-phenylpropanamide;N-[6-fluoro-3-[(E)-2-pyridin-3-ylethenyl]-1H-indazol-5-yl]-3-hydroxy-2,2-dimethylpropanamide;N-[6-fluoro-3-[(E)-2-pyridin-3-ylethenyl]-1H-indazol-5-yl]-3-hydroxy-3-methylbutanamide?

The canonical SMILES for 1-N'-[6-fluoro-3-[(E)-2-(4-fluorophenyl)ethenyl]-1H-indazol-5-yl]cyclopropane-1,1-dicarboxamide;N-[6-fluoro-3-[(E)-2-(4-fluorophenyl)ethenyl]-1H-indazol-5-yl]-3-hydroxybutanamide;(3R)-N-[6-fluoro-3-[(E)-2-(4-fluorophenyl)ethenyl]-1H-indazol-5-yl]-3-hydroxy-3-phenylpropanamide;N-[6-fluoro-3-[(E)-2-pyridin-3-ylethenyl]-1H-indazol-5-yl]-3-hydroxy-2,2-dimethylpropanamide;N-[6-fluoro-3-[(E)-2-pyridin-3-ylethenyl]-1H-indazol-5-yl]-3-hydroxy-3-methylbutanamide is CC(C)(CO)C(=O)Nc1cc2c(/C=C/c3cccnc3)n[nH]c2cc1F.CC(C)(O)CC(=O)Nc1cc2c(/C=C/c3cccnc3)n[nH]c2cc1F.CC(O)CC(=O)Nc1cc2c(/C=C/c3ccc(F)cc3)n[nH]c2cc1F.NC(=O)C1(C(=O)Nc2cc3c(/C=C/c4ccc(F)cc4)n[nH]c3cc2F)CC1.O=C(C[C@@H](O)c1ccccc1)Nc1cc2c(/C=C/c3ccc(F)cc3)n[nH]c2cc1F.

What is the InChIKey of 1-N'-[6-fluoro-3-[(E)-2-(4-fluorophenyl)ethenyl]-1H-indazol-5-yl]cyclopropane-1,1-dicarboxamide;N-[6-fluoro-3-[(E)-2-(4-fluorophenyl)ethenyl]-1H-indazol-5-yl]-3-hydroxybutanamide;(3R)-N-[6-fluoro-3-[(E)-2-(4-fluorophenyl)ethenyl]-1H-indazol-5-yl]-3-hydroxy-3-phenylpropanamide;N-[6-fluoro-3-[(E)-2-pyridin-3-ylethenyl]-1H-indazol-5-yl]-3-hydroxy-2,2-dimethylpropanamide;N-[6-fluoro-3-[(E)-2-pyridin-3-ylethenyl]-1H-indazol-5-yl]-3-hydroxy-3-methylbutanamide?

The InChIKey is LYIFZWOWDOWZHB-SPYRSNAPSA-N. The full InChI is InChI=1S/C24H19F2N3O2.C20H16F2N4O2.C19H17F2N3O2.2C19H19FN4O2/c25-17-9-6-15(7-10-17)8-11-20-18-12-22(19(26)13-21(18)29-28-20)27-24(31)14-23(30)16-4-2-1-3-5-16;21-12-4-1-11(2-5-12)3-6-15-13-9-17(14(22)10-16(13)26-25-15)24-19(28)20(7-8-20)18(23)27;1-11(25)8-19(26)22-18-9-14-16(23-24-17(14)10-15(18)21)7-4-12-2-5-13(20)6-3-12;1-19(2,26)10-18(25)22-17-8-13-15(23-24-16(13)9-14(17)20)6-5-12-4-3-7-21-11-12;1-19(2,11-25)18(26)22-17-8-13-15(23-24-16(13)9-14(17)20)6-5-12-4-3-7-21-10-12/h1-13,23,30H,14H2,(H,27,31)(H,28,29);1-6,9-10H,7-8H2,(H2,23,27)(H,24,28)(H,25,26);2-7,9-11,25H,8H2,1H3,(H,22,26)(H,23,24);3-9,11,26H,10H2,1-2H3,(H,22,25)(H,23,24);3-10,25H,11H2,1-2H3,(H,22,26)(H,23,24)/b11-8+;6-3+;7-4+;2*6-5+/t23-;;;;/m1..../s1.

What are the key properties of 1-N'-[6-fluoro-3-[(E)-2-(4-fluorophenyl)ethenyl]-1H-indazol-5-yl]cyclopropane-1,1-dicarboxamide;N-[6-fluoro-3-[(E)-2-(4-fluorophenyl)ethenyl]-1H-indazol-5-yl]-3-hydroxybutanamide;(3R)-N-[6-fluoro-3-[(E)-2-(4-fluorophenyl)ethenyl]-1H-indazol-5-yl]-3-hydroxy-3-phenylpropanamide;N-[6-fluoro-3-[(E)-2-pyridin-3-ylethenyl]-1H-indazol-5-yl]-3-hydroxy-2,2-dimethylpropanamide;N-[6-fluoro-3-[(E)-2-pyridin-3-ylethenyl]-1H-indazol-5-yl]-3-hydroxy-3-methylbutanamide?

1-N'-[6-fluoro-3-[(E)-2-(4-fluorophenyl)ethenyl]-1H-indazol-5-yl]cyclopropane-1,1-dicarboxamide;N-[6-fluoro-3-[(E)-2-(4-fluorophenyl)ethenyl]-1H-indazol-5-yl]-3-hydroxybutanamide;(3R)-N-[6-fluoro-3-[(E)-2-(4-fluorophenyl)ethenyl]-1H-indazol-5-yl]-3-hydroxy-3-phenylpropanamide;N-[6-fluoro-3-[(E)-2-pyridin-3-ylethenyl]-1H-indazol-5-yl]-3-hydroxy-2,2-dimethylpropanamide;N-[6-fluoro-3-[(E)-2-pyridin-3-ylethenyl]-1H-indazol-5-yl]-3-hydroxy-3-methylbutanamide has a molecular weight of 1867.93 g/mol, XLogP of 18.60, 26 rotatable bonds, 15 hydrogen bond donors, and 17 hydrogen bond acceptors.

Where does this data come from?

All data for 1-N'-[6-fluoro-3-[(E)-2-(4-fluorophenyl)ethenyl]-1H-indazol-5-yl]cyclopropane-1,1-dicarboxamide;N-[6-fluoro-3-[(E)-2-(4-fluorophenyl)ethenyl]-1H-indazol-5-yl]-3-hydroxybutanamide;(3R)-N-[6-fluoro-3-[(E)-2-(4-fluorophenyl)ethenyl]-1H-indazol-5-yl]-3-hydroxy-3-phenylpropanamide;N-[6-fluoro-3-[(E)-2-pyridin-3-ylethenyl]-1H-indazol-5-yl]-3-hydroxy-2,2-dimethylpropanamide;N-[6-fluoro-3-[(E)-2-pyridin-3-ylethenyl]-1H-indazol-5-yl]-3-hydroxy-3-methylbutanamide is sourced from PubChem (CID 159492171), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).