2-(difluoromethyl)-5-[3-(2,3-difluorophenyl)imidazo[1,5-a]pyridin-8-yl]-N-(4-methylphenyl)benzamide;5-[3-(3-fluorophenyl)imidazo[1,5-a]pyridin-8-yl]-N-(4-methylphenyl)-2-(trifluoromethyl)benzamide;2-methyl-N-(4-methylphenyl)-5-[3-(1,3-oxazol-2-yl)imidazo[1,5-a]pyridin-8-yl]benzamide;2-methyl-N-(4-methylphenyl)-5-(3-pyrimidin-2-ylimidazo[1,5-a]pyridin-8-yl)benzamide

C107H79F8N15O5 — CID 159495245

About 2-(difluoromethyl)-5-[3-(2,3-difluorophenyl)imidazo[1,5-a]pyridin-8-yl]-N-(4-methylphenyl)benzamide;5-[3-(3-fluorophenyl)imidazo[1,5-a]pyridin-8-yl]-N-(4-methylphenyl)-2-(trifluoromethyl)benzamide;2-methyl-N-(4-methylphenyl)-5-[3-(1,3-oxazol-2-yl)imidazo[1,5-a]pyridin-8-yl]benzamide;2-methyl-N-(4-methylphenyl)-5-(3-pyrimidin-2-ylimidazo[1,5-a]pyridin-8-yl)benzamide

2-(difluoromethyl)-5-[3-(2,3-difluorophenyl)imidazo[1,5-a]pyridin-8-yl]-N-(4-methylphenyl)benzamide;5-[3-(3-fluorophenyl)imidazo[1,5-a]pyridin-8-yl]-N-(4-methylphenyl)-2-(trifluoromethyl)benzamide;2-methyl-N-(4-methylphenyl)-5-[3-(1,3-oxazol-2-yl)imidazo[1,5-a]pyridin-8-yl]benzamide;2-methyl-N-(4-methylphenyl)-5-(3-pyrimidin-2-ylimidazo[1,5-a]pyridin-8-yl)benzamide (PubChem CID 159495245) has the molecular formula C107H79F8N15O5 and a molecular weight of 1806.89 g/mol. Its IUPAC name is 2-(difluoromethyl)-5-[3-(2,3-difluorophenyl)imidazo[1,5-a]pyridin-8-yl]-N-(4-methylphenyl)benzamide;5-[3-(3-fluorophenyl)imidazo[1,5-a]pyridin-8-yl]-N-(4-methylphenyl)-2-(trifluoromethyl)benzamide;2-methyl-N-(4-methylphenyl)-5-[3-(1,3-oxazol-2-yl)imidazo[1,5-a]pyridin-8-yl]benzamide;2-methyl-N-(4-methylphenyl)-5-(3-pyrimidin-2-ylimidazo[1,5-a]pyridin-8-yl)benzamide.

Molecular Properties

• Compound Name: 2-(difluoromethyl)-5-[3-(2,3-difluorophenyl)imidazo[1,5-a]pyridin-8-yl]-N-(4-methylphenyl)benzamide;5-[3-(3-fluorophenyl)imidazo[1,5-a]pyridin-8-yl]-N-(4-methylphenyl)-2-(trifluoromethyl)benzamide;2-methyl-N-(4-methylphenyl)-5-[3-(1,3-oxazol-2-yl)imidazo[1,5-a]pyridin-8-yl]benzamide;2-methyl-N-(4-methylphenyl)-5-(3-pyrimidin-2-ylimidazo[1,5-a]pyridin-8-yl)benzamide
• PubChem CID: 159495245
• Molecular Formula: C107H79F8N15O5
• Molecular Weight: 1806.89 g/mol
• Exact Mass: 1805.63
• IUPAC Name: 2-(difluoromethyl)-5-[3-(2,3-difluorophenyl)imidazo[1,5-a]pyridin-8-yl]-N-(4-methylphenyl)benzamide;5-[3-(3-fluorophenyl)imidazo[1,5-a]pyridin-8-yl]-N-(4-methylphenyl)-2-(trifluoromethyl)benzamide;2-methyl-N-(4-methylphenyl)-5-[3-(1,3-oxazol-2-yl)imidazo[1,5-a]pyridin-8-yl]benzamide;2-methyl-N-(4-methylphenyl)-5-(3-pyrimidin-2-ylimidazo[1,5-a]pyridin-8-yl)benzamide
• SMILES: Cc1ccc(NC(=O)c2cc(-c3cccn4c(-c5cccc(F)c5)ncc34)ccc2C(F)(F)F)cc1.Cc1ccc(NC(=O)c2cc(-c3cccn4c(-c5cccc(F)c5F)ncc34)ccc2C(F)F)cc1.Cc1ccc(NC(=O)c2cc(-c3cccn4c(-c5ncccn5)ncc34)ccc2C)cc1.Cc1ccc(NC(=O)c2cc(-c3cccn4c(-c5ncco5)ncc34)ccc2C)cc1
• InChI: InChI=1S/2C28H19F4N3O.C26H21N5O.C25H20N4O2/c1-16-7-10-18(11-8-16)34-28(36)22-14-17(9-12-20(22)26(31)32)19-5-3-13-35-24(19)15-33-27(35)21-4-2-6-23(29)25(21)30;1-17-7-10-21(11-8-17)34-27(36)23-15-18(9-12-24(23)28(30,31)32)22-6-3-13-35-25(22)16-33-26(35)19-4-2-5-20(29)14-19;1-17-6-10-20(11-7-17)30-26(32)22-15-19(9-8-18(22)2)21-5-3-14-31-23(21)16-29-25(31)24-27-12-4-13-28-24;1-16-5-9-19(10-6-16)28-24(30)21-14-18(8-7-17(21)2)20-4-3-12-29-22(20)15-27-23(29)25-26-11-13-31-25/h2-15,26H,1H3,(H,34,36);2-16H,1H3,(H,34,36);3-16H,1-2H3,(H,30,32);3-15H,1-2H3,(H,28,30)
• InChIKey: LYRUPZJKRAYJQE-UHFFFAOYSA-N
• XLogP: 25.68
• TPSA: 237.41 Ų
• H-Bond Donors: 4
• H-Bond Acceptors: 16
• Rotatable Bonds: 17
• Heavy Atoms: 135
• Complexity: —

Lipinski Rule of Five

3 violations

Rule	Value
MW ≤ 500	1806.89
LogP ≤ 5	25.68
H-Bond Donors ≤ 5	4
H-Bond Acceptors ≤ 10	16

Frequently Asked Questions

What is the IUPAC name of 2-(difluoromethyl)-5-[3-(2,3-difluorophenyl)imidazo[1,5-a]pyridin-8-yl]-N-(4-methylphenyl)benzamide;5-[3-(3-fluorophenyl)imidazo[1,5-a]pyridin-8-yl]-N-(4-methylphenyl)-2-(trifluoromethyl)benzamide;2-methyl-N-(4-methylphenyl)-5-[3-(1,3-oxazol-2-yl)imidazo[1,5-a]pyridin-8-yl]benzamide;2-methyl-N-(4-methylphenyl)-5-(3-pyrimidin-2-ylimidazo[1,5-a]pyridin-8-yl)benzamide?

The IUPAC name of 2-(difluoromethyl)-5-[3-(2,3-difluorophenyl)imidazo[1,5-a]pyridin-8-yl]-N-(4-methylphenyl)benzamide;5-[3-(3-fluorophenyl)imidazo[1,5-a]pyridin-8-yl]-N-(4-methylphenyl)-2-(trifluoromethyl)benzamide;2-methyl-N-(4-methylphenyl)-5-[3-(1,3-oxazol-2-yl)imidazo[1,5-a]pyridin-8-yl]benzamide;2-methyl-N-(4-methylphenyl)-5-(3-pyrimidin-2-ylimidazo[1,5-a]pyridin-8-yl)benzamide (CID 159495245) is 2-(difluoromethyl)-5-[3-(2,3-difluorophenyl)imidazo[1,5-a]pyridin-8-yl]-N-(4-methylphenyl)benzamide;5-[3-(3-fluorophenyl)imidazo[1,5-a]pyridin-8-yl]-N-(4-methylphenyl)-2-(trifluoromethyl)benzamide;2-methyl-N-(4-methylphenyl)-5-[3-(1,3-oxazol-2-yl)imidazo[1,5-a]pyridin-8-yl]benzamide;2-methyl-N-(4-methylphenyl)-5-(3-pyrimidin-2-ylimidazo[1,5-a]pyridin-8-yl)benzamide.

What is the SMILES notation for 2-(difluoromethyl)-5-[3-(2,3-difluorophenyl)imidazo[1,5-a]pyridin-8-yl]-N-(4-methylphenyl)benzamide;5-[3-(3-fluorophenyl)imidazo[1,5-a]pyridin-8-yl]-N-(4-methylphenyl)-2-(trifluoromethyl)benzamide;2-methyl-N-(4-methylphenyl)-5-[3-(1,3-oxazol-2-yl)imidazo[1,5-a]pyridin-8-yl]benzamide;2-methyl-N-(4-methylphenyl)-5-(3-pyrimidin-2-ylimidazo[1,5-a]pyridin-8-yl)benzamide?

The canonical SMILES for 2-(difluoromethyl)-5-[3-(2,3-difluorophenyl)imidazo[1,5-a]pyridin-8-yl]-N-(4-methylphenyl)benzamide;5-[3-(3-fluorophenyl)imidazo[1,5-a]pyridin-8-yl]-N-(4-methylphenyl)-2-(trifluoromethyl)benzamide;2-methyl-N-(4-methylphenyl)-5-[3-(1,3-oxazol-2-yl)imidazo[1,5-a]pyridin-8-yl]benzamide;2-methyl-N-(4-methylphenyl)-5-(3-pyrimidin-2-ylimidazo[1,5-a]pyridin-8-yl)benzamide is Cc1ccc(NC(=O)c2cc(-c3cccn4c(-c5cccc(F)c5)ncc34)ccc2C(F)(F)F)cc1.Cc1ccc(NC(=O)c2cc(-c3cccn4c(-c5cccc(F)c5F)ncc34)ccc2C(F)F)cc1.Cc1ccc(NC(=O)c2cc(-c3cccn4c(-c5ncccn5)ncc34)ccc2C)cc1.Cc1ccc(NC(=O)c2cc(-c3cccn4c(-c5ncco5)ncc34)ccc2C)cc1.

What is the InChIKey of 2-(difluoromethyl)-5-[3-(2,3-difluorophenyl)imidazo[1,5-a]pyridin-8-yl]-N-(4-methylphenyl)benzamide;5-[3-(3-fluorophenyl)imidazo[1,5-a]pyridin-8-yl]-N-(4-methylphenyl)-2-(trifluoromethyl)benzamide;2-methyl-N-(4-methylphenyl)-5-[3-(1,3-oxazol-2-yl)imidazo[1,5-a]pyridin-8-yl]benzamide;2-methyl-N-(4-methylphenyl)-5-(3-pyrimidin-2-ylimidazo[1,5-a]pyridin-8-yl)benzamide?

The InChIKey is LYRUPZJKRAYJQE-UHFFFAOYSA-N. The full InChI is InChI=1S/2C28H19F4N3O.C26H21N5O.C25H20N4O2/c1-16-7-10-18(11-8-16)34-28(36)22-14-17(9-12-20(22)26(31)32)19-5-3-13-35-24(19)15-33-27(35)21-4-2-6-23(29)25(21)30;1-17-7-10-21(11-8-17)34-27(36)23-15-18(9-12-24(23)28(30,31)32)22-6-3-13-35-25(22)16-33-26(35)19-4-2-5-20(29)14-19;1-17-6-10-20(11-7-17)30-26(32)22-15-19(9-8-18(22)2)21-5-3-14-31-23(21)16-29-25(31)24-27-12-4-13-28-24;1-16-5-9-19(10-6-16)28-24(30)21-14-18(8-7-17(21)2)20-4-3-12-29-22(20)15-27-23(29)25-26-11-13-31-25/h2-15,26H,1H3,(H,34,36);2-16H,1H3,(H,34,36);3-16H,1-2H3,(H,30,32);3-15H,1-2H3,(H,28,30).

What are the key properties of 2-(difluoromethyl)-5-[3-(2,3-difluorophenyl)imidazo[1,5-a]pyridin-8-yl]-N-(4-methylphenyl)benzamide;5-[3-(3-fluorophenyl)imidazo[1,5-a]pyridin-8-yl]-N-(4-methylphenyl)-2-(trifluoromethyl)benzamide;2-methyl-N-(4-methylphenyl)-5-[3-(1,3-oxazol-2-yl)imidazo[1,5-a]pyridin-8-yl]benzamide;2-methyl-N-(4-methylphenyl)-5-(3-pyrimidin-2-ylimidazo[1,5-a]pyridin-8-yl)benzamide?

2-(difluoromethyl)-5-[3-(2,3-difluorophenyl)imidazo[1,5-a]pyridin-8-yl]-N-(4-methylphenyl)benzamide;5-[3-(3-fluorophenyl)imidazo[1,5-a]pyridin-8-yl]-N-(4-methylphenyl)-2-(trifluoromethyl)benzamide;2-methyl-N-(4-methylphenyl)-5-[3-(1,3-oxazol-2-yl)imidazo[1,5-a]pyridin-8-yl]benzamide;2-methyl-N-(4-methylphenyl)-5-(3-pyrimidin-2-ylimidazo[1,5-a]pyridin-8-yl)benzamide has a molecular weight of 1806.89 g/mol, XLogP of 25.68, 17 rotatable bonds, 4 hydrogen bond donors, and 16 hydrogen bond acceptors.

Where does this data come from?

All data for 2-(difluoromethyl)-5-[3-(2,3-difluorophenyl)imidazo[1,5-a]pyridin-8-yl]-N-(4-methylphenyl)benzamide;5-[3-(3-fluorophenyl)imidazo[1,5-a]pyridin-8-yl]-N-(4-methylphenyl)-2-(trifluoromethyl)benzamide;2-methyl-N-(4-methylphenyl)-5-[3-(1,3-oxazol-2-yl)imidazo[1,5-a]pyridin-8-yl]benzamide;2-methyl-N-(4-methylphenyl)-5-(3-pyrimidin-2-ylimidazo[1,5-a]pyridin-8-yl)benzamide is sourced from PubChem (CID 159495245), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).