2-(2-tert-butyl-1,3-thiazol-5-yl)-5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-N-methyl-6-[methyl(methylsulfonyl)amino]-1-benzofuran-3-carboxamide;2-cyclopropyl-5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-N-methyl-6-[methyl(methylsulfonyl)amino]-1-benzofuran-3-carboxamide;2-(5,6-dihydro-4H-pyrrolo[2,1-e]pyrazol-3-yl)-5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-N-methyl-6-[methyl(methylsulfonyl)amino]-1-benzofuran-3-carboxamide;5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-N-methyl-6-[methyl(methylsulfonyl)amino]-2-(1-phenylpyrazol-4-yl)-1-benzofuran-3-carboxamide;5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-N-methyl-6-[methyl(methylsulfonyl)amino]-2-(1-propan-2-ylpyrrol-2-yl)-1-benzofuran-3-carboxamide;5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-N-methyl-6-[methyl(methylsulfonyl)amino]-2-(2-pyrrolidin-1-yl-1,3-thiazol-5-yl)-1-benzofuran-3-carboxamide;5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-N-methyl-6-[methyl(methylsulfonyl)amino]-2-(4,5,6,7-tetrahydropyrazolo[1,5-a]pyridin-3-yl)-1-benzofuran-3-carboxamide

C235H211F7N38O28S9 — CID 159500408

IUPAC2-(2-tert-butyl-1,3-thiazol-5-yl)-5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-N-methyl-6-[methyl(methylsulfonyl)amino]-1-benzofuran-3-carboxamide;2-cyclopropyl-5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-N-methyl-6-[methyl(methylsulfonyl)amino]-1-benzofuran-3-carboxamide;2-(5,6-dihydro-4H-pyrrolo[2,1-e]pyrazol-3-yl)-5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-N-methyl-6-[methyl(methylsulfonyl)amino]-1-benzofuran-3-carboxamide;5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-N-methyl-6-[methyl(methylsulfonyl)amino]-2-(1-phenylpyrazol-4-yl)-1-benzofuran-3-carboxamide;5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-N-methyl-6-[methyl(methylsulfonyl)amino]-2-(1-propan-2-ylpyrrol-2-yl)-1-benzofuran-3-carboxamide;5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-N-methyl-6-[methyl(methylsulfonyl)amino]-2-(2-pyrrolidin-1-yl-1,3-thiazol-5-yl)-1-benzofuran-3-carboxamide;5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-N-methyl-6-[methyl(methylsulfonyl)amino]-2-(4,5,6,7-tetrahydropyrazolo[1,5-a]pyridin-3-yl)-1-benzofuran-3-carboxamide
SMILESCNC(=O)c1c(-c2cccn2C(C)C)oc2cc(N(C)S(C)(=O)=O)c(-c3ccc4c(n3)-c3cc5c(F)cccc5n3CC4)cc12.CNC(=O)c1c(-c2cnc(C(C)(C)C)s2)oc2cc(N(C)S(C)(=O)=O)c(-c3ccc4c(n3)-c3cc5c(F)cccc5n3CC4)cc12.CNC(=O)c1c(-c2cnc(N3CCCC3)s2)oc2cc(N(C)S(C)(=O)=O)c(-c3ccc4c(n3)-c3cc5c(F)cccc5n3CC4)cc12.CNC(=O)c1c(-c2cnn(-c3ccccc3)c2)oc2cc(N(C)S(C)(=O)=O)c(-c3ccc4c(n3)-c3cc5c(F)cccc5n3CC4)cc12.CNC(=O)c1c(-c2cnn3c2CCC3)oc2cc(N(C)S(C)(=O)=O)c(-c3ccc4c(n3)-c3cc5c(F)cccc5n3CC4)cc12.CNC(=O)c1c(-c2cnn3c2CCCC3)oc2cc(N(C)S(C)(=O)=O)c(-c3ccc4c(n3)-c3cc5c(F)cccc5n3CC4)cc12.CNC(=O)c1c(C2CC2)oc2cc(N(C)S(C)(=O)=O)c(-c3ccc4c(n3)-c3cc5c(F)cccc5n3CC4)cc12
InChIInChI=1S/C36H29FN6O4S.C34H31FN6O4S2.C34H31FN6O4S.C34H32FN5O4S2.C34H32FN5O4S.C33H29FN6O4S.C30H27FN4O4S/c1-38-36(44)33-26-16-25(28-13-12-21-14-15-42-29-11-7-10-27(37)24(29)17-31(42)34(21)40-28)30(41(2)48(3,45)46)18-32(26)47-35(33)22-19-39-43(20-22)23-8-5-4-6-9-23;1-36-33(42)30-22-15-21(24-10-9-19-11-14-41-25-8-6-7-23(35)20(25)16-27(41)31(19)38-24)26(39(2)47(3,43)44)17-28(22)45-32(30)29-18-37-34(46-29)40-12-4-5-13-40;1-36-34(42)31-22-15-21(25-11-10-19-12-14-40-26-9-6-7-24(35)20(26)16-29(40)32(19)38-25)28(39(2)46(3,43)44)17-30(22)45-33(31)23-18-37-41-13-5-4-8-27(23)41;1-34(2,3)33-37-17-28(45-33)31-29(32(41)36-4)21-14-20(25(16-27(21)44-31)39(5)46(6,42)43)23-11-10-18-12-13-40-24-9-7-8-22(35)19(24)15-26(40)30(18)38-23;1-19(2)39-14-7-10-27(39)33-31(34(41)36-3)23-16-22(28(18-30(23)44-33)38(4)45(5,42)43)25-12-11-20-13-15-40-26-9-6-8-24(35)21(26)17-29(40)32(20)37-25;1-35-33(41)30-21-14-20(24-10-9-18-11-13-39-25-7-4-6-23(34)19(25)15-28(39)31(18)37-24)27(38(2)45(3,42)43)16-29(21)44-32(30)22-17-36-40-12-5-8-26(22)40;1-32-30(36)27-20-13-19(24(34(2)40(3,37)38)15-26(20)39-29(27)17-7-8-17)22-10-9-16-11-12-35-23-6-4-5-21(31)18(23)14-25(35)28(16)33-22/h4-13,16-20H,14-15H2,1-3H3,(H,38,44);6-10,15-18H,4-5,11-14H2,1-3H3,(H,36,42);6-7,9-11,15-18H,4-5,8,12-14H2,1-3H3,(H,36,42);7-11,14-17H,12-13H2,1-6H3,(H,36,41);6-12,14,16-19H,13,15H2,1-5H3,(H,36,41);4,6-7,9-10,14-17H,5,8,11-13H2,1-3H3,(H,35,41);4-6,9-10,13-15,17H,7-8,11-12H2,1-3H3,(H,32,36)
InChIKeyLZHVCYHIWTTZHM-UHFFFAOYSA-N
MW4437.10 g/mol
LogP42.90
Rot. Bonds38

About 2-(2-tert-butyl-1,3-thiazol-5-yl)-5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-N-methyl-6-[methyl(methylsulfonyl)amino]-1-benzofuran-3-carboxamide;2-cyclopropyl-5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-N-methyl-6-[methyl(methylsulfonyl)amino]-1-benzofuran-3-carboxamide;2-(5,6-dihydro-4H-pyrrolo[2,1-e]pyrazol-3-yl)-5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-N-methyl-6-[methyl(methylsulfonyl)amino]-1-benzofuran-3-carboxamide;5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-N-methyl-6-[methyl(methylsulfonyl)amino]-2-(1-phenylpyrazol-4-yl)-1-benzofuran-3-carboxamide;5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-N-methyl-6-[methyl(methylsulfonyl)amino]-2-(1-propan-2-ylpyrrol-2-yl)-1-benzofuran-3-carboxamide;5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-N-methyl-6-[methyl(methylsulfonyl)amino]-2-(2-pyrrolidin-1-yl-1,3-thiazol-5-yl)-1-benzofuran-3-carboxamide;5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-N-methyl-6-[methyl(methylsulfonyl)amino]-2-(4,5,6,7-tetrahydropyrazolo[1,5-a]pyridin-3-yl)-1-benzofuran-3-carboxamide

2-(2-tert-butyl-1,3-thiazol-5-yl)-5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-N-methyl-6-[methyl(methylsulfonyl)amino]-1-benzofuran-3-carboxamide;2-cyclopropyl-5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-N-methyl-6-[methyl(methylsulfonyl)amino]-1-benzofuran-3-carboxamide;2-(5,6-dihydro-4H-pyrrolo[2,1-e]pyrazol-3-yl)-5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-N-methyl-6-[methyl(methylsulfonyl)amino]-1-benzofuran-3-carboxamide;5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-N-methyl-6-[methyl(methylsulfonyl)amino]-2-(1-phenylpyrazol-4-yl)-1-benzofuran-3-carboxamide;5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-N-methyl-6-[methyl(methylsulfonyl)amino]-2-(1-propan-2-ylpyrrol-2-yl)-1-benzofuran-3-carboxamide;5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-N-methyl-6-[methyl(methylsulfonyl)amino]-2-(2-pyrrolidin-1-yl-1,3-thiazol-5-yl)-1-benzofuran-3-carboxamide;5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-N-methyl-6-[methyl(methylsulfonyl)amino]-2-(4,5,6,7-tetrahydropyrazolo[1,5-a]pyridin-3-yl)-1-benzofuran-3-carboxamide (PubChem CID 159500408) has the molecular formula C235H211F7N38O28S9 and a molecular weight of 4437.10 g/mol. Its IUPAC name is 2-(2-tert-butyl-1,3-thiazol-5-yl)-5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-N-methyl-6-[methyl(methylsulfonyl)amino]-1-benzofuran-3-carboxamide;2-cyclopropyl-5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-N-methyl-6-[methyl(methylsulfonyl)amino]-1-benzofuran-3-carboxamide;2-(5,6-dihydro-4H-pyrrolo[2,1-e]pyrazol-3-yl)-5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-N-methyl-6-[methyl(methylsulfonyl)amino]-1-benzofuran-3-carboxamide;5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-N-methyl-6-[methyl(methylsulfonyl)amino]-2-(1-phenylpyrazol-4-yl)-1-benzofuran-3-carboxamide;5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-N-methyl-6-[methyl(methylsulfonyl)amino]-2-(1-propan-2-ylpyrrol-2-yl)-1-benzofuran-3-carboxamide;5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-N-methyl-6-[methyl(methylsulfonyl)amino]-2-(2-pyrrolidin-1-yl-1,3-thiazol-5-yl)-1-benzofuran-3-carboxamide;5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-N-methyl-6-[methyl(methylsulfonyl)amino]-2-(4,5,6,7-tetrahydropyrazolo[1,5-a]pyridin-3-yl)-1-benzofuran-3-carboxamide.

Molecular Properties

Compound Name2-(2-tert-butyl-1,3-thiazol-5-yl)-5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-N-methyl-6-[methyl(methylsulfonyl)amino]-1-benzofuran-3-carboxamide;2-cyclopropyl-5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-N-methyl-6-[methyl(methylsulfonyl)amino]-1-benzofuran-3-carboxamide;2-(5,6-dihydro-4H-pyrrolo[2,1-e]pyrazol-3-yl)-5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-N-methyl-6-[methyl(methylsulfonyl)amino]-1-benzofuran-3-carboxamide;5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-N-methyl-6-[methyl(methylsulfonyl)amino]-2-(1-phenylpyrazol-4-yl)-1-benzofuran-3-carboxamide;5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-N-methyl-6-[methyl(methylsulfonyl)amino]-2-(1-propan-2-ylpyrrol-2-yl)-1-benzofuran-3-carboxamide;5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-N-methyl-6-[methyl(methylsulfonyl)amino]-2-(2-pyrrolidin-1-yl-1,3-thiazol-5-yl)-1-benzofuran-3-carboxamide;5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-N-methyl-6-[methyl(methylsulfonyl)amino]-2-(4,5,6,7-tetrahydropyrazolo[1,5-a]pyridin-3-yl)-1-benzofuran-3-carboxamide
PubChem CID159500408
Molecular FormulaC235H211F7N38O28S9
Molecular Weight4437.10 g/mol
Exact Mass4433.36
IUPAC Name2-(2-tert-butyl-1,3-thiazol-5-yl)-5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-N-methyl-6-[methyl(methylsulfonyl)amino]-1-benzofuran-3-carboxamide;2-cyclopropyl-5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-N-methyl-6-[methyl(methylsulfonyl)amino]-1-benzofuran-3-carboxamide;2-(5,6-dihydro-4H-pyrrolo[2,1-e]pyrazol-3-yl)-5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-N-methyl-6-[methyl(methylsulfonyl)amino]-1-benzofuran-3-carboxamide;5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-N-methyl-6-[methyl(methylsulfonyl)amino]-2-(1-phenylpyrazol-4-yl)-1-benzofuran-3-carboxamide;5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-N-methyl-6-[methyl(methylsulfonyl)amino]-2-(1-propan-2-ylpyrrol-2-yl)-1-benzofuran-3-carboxamide;5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-N-methyl-6-[methyl(methylsulfonyl)amino]-2-(2-pyrrolidin-1-yl-1,3-thiazol-5-yl)-1-benzofuran-3-carboxamide;5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-N-methyl-6-[methyl(methylsulfonyl)amino]-2-(4,5,6,7-tetrahydropyrazolo[1,5-a]pyridin-3-yl)-1-benzofuran-3-carboxamide
SMILESCNC(=O)c1c(-c2cccn2C(C)C)oc2cc(N(C)S(C)(=O)=O)c(-c3ccc4c(n3)-c3cc5c(F)cccc5n3CC4)cc12.CNC(=O)c1c(-c2cnc(C(C)(C)C)s2)oc2cc(N(C)S(C)(=O)=O)c(-c3ccc4c(n3)-c3cc5c(F)cccc5n3CC4)cc12.CNC(=O)c1c(-c2cnc(N3CCCC3)s2)oc2cc(N(C)S(C)(=O)=O)c(-c3ccc4c(n3)-c3cc5c(F)cccc5n3CC4)cc12.CNC(=O)c1c(-c2cnn(-c3ccccc3)c2)oc2cc(N(C)S(C)(=O)=O)c(-c3ccc4c(n3)-c3cc5c(F)cccc5n3CC4)cc12.CNC(=O)c1c(-c2cnn3c2CCC3)oc2cc(N(C)S(C)(=O)=O)c(-c3ccc4c(n3)-c3cc5c(F)cccc5n3CC4)cc12.CNC(=O)c1c(-c2cnn3c2CCCC3)oc2cc(N(C)S(C)(=O)=O)c(-c3ccc4c(n3)-c3cc5c(F)cccc5n3CC4)cc12.CNC(=O)c1c(C2CC2)oc2cc(N(C)S(C)(=O)=O)c(-c3ccc4c(n3)-c3cc5c(F)cccc5n3CC4)cc12
InChIInChI=1S/C36H29FN6O4S.C34H31FN6O4S2.C34H31FN6O4S.C34H32FN5O4S2.C34H32FN5O4S.C33H29FN6O4S.C30H27FN4O4S/c1-38-36(44)33-26-16-25(28-13-12-21-14-15-42-29-11-7-10-27(37)24(29)17-31(42)34(21)40-28)30(41(2)48(3,45)46)18-32(26)47-35(33)22-19-39-43(20-22)23-8-5-4-6-9-23;1-36-33(42)30-22-15-21(24-10-9-19-11-14-41-25-8-6-7-23(35)20(25)16-27(41)31(19)38-24)26(39(2)47(3,43)44)17-28(22)45-32(30)29-18-37-34(46-29)40-12-4-5-13-40;1-36-34(42)31-22-15-21(25-11-10-19-12-14-40-26-9-6-7-24(35)20(26)16-29(40)32(19)38-25)28(39(2)46(3,43)44)17-30(22)45-33(31)23-18-37-41-13-5-4-8-27(23)41;1-34(2,3)33-37-17-28(45-33)31-29(32(41)36-4)21-14-20(25(16-27(21)44-31)39(5)46(6,42)43)23-11-10-18-12-13-40-24-9-7-8-22(35)19(24)15-26(40)30(18)38-23;1-19(2)39-14-7-10-27(39)33-31(34(41)36-3)23-16-22(28(18-30(23)44-33)38(4)45(5,42)43)25-12-11-20-13-15-40-26-9-6-8-24(35)21(26)17-29(40)32(20)37-25;1-35-33(41)30-21-14-20(24-10-9-18-11-13-39-25-7-4-6-23(34)19(25)15-28(39)31(18)37-24)27(38(2)45(3,42)43)16-29(21)44-32(30)22-17-36-40-12-5-8-26(22)40;1-32-30(36)27-20-13-19(24(34(2)40(3,37)38)15-26(20)39-29(27)17-7-8-17)22-10-9-16-11-12-35-23-6-4-5-21(31)18(23)14-25(35)28(16)33-22/h4-13,16-20H,14-15H2,1-3H3,(H,38,44);6-10,15-18H,4-5,11-14H2,1-3H3,(H,36,42);6-7,9-11,15-18H,4-5,8,12-14H2,1-3H3,(H,36,42);7-11,14-17H,12-13H2,1-6H3,(H,36,41);6-12,14,16-19H,13,15H2,1-5H3,(H,36,41);4,6-7,9-10,14-17H,5,8,11-13H2,1-3H3,(H,35,41);4-6,9-10,13-15,17H,7-8,11-12H2,1-3H3,(H,32,36)
InChIKeyLZHVCYHIWTTZHM-UHFFFAOYSA-N
XLogP42.90
TPSA769.49 Ų
H-Bond Donors7
H-Bond Acceptors54
Rotatable Bonds38
Heavy Atoms317
Complexity—

Lipinski Rule of Five

4 violations

RuleValue
MW ≤ 5004437.10
LogP ≤ 542.90
H-Bond Donors ≤ 57
H-Bond Acceptors ≤ 1054

Analyze 2-(2-tert-butyl-1,3-thiazol-5-yl)-5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-N-methyl-6-[methyl(methylsulfonyl)amino]-1-benzofuran-3-carboxamide;2-cyclopropyl-5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-N-methyl-6-[methyl(methylsulfonyl)amino]-1-benzofuran-3-carboxamide;2-(5,6-dihydro-4H-pyrrolo[2,1-e]pyrazol-3-yl)-5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-N-methyl-6-[methyl(methylsulfonyl)amino]-1-benzofuran-3-carboxamide;5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-N-methyl-6-[methyl(methylsulfonyl)amino]-2-(1-phenylpyrazol-4-yl)-1-benzofuran-3-carboxamide;5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-N-methyl-6-[methyl(methylsulfonyl)amino]-2-(1-propan-2-ylpyrrol-2-yl)-1-benzofuran-3-carboxamide;5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-N-methyl-6-[methyl(methylsulfonyl)amino]-2-(2-pyrrolidin-1-yl-1,3-thiazol-5-yl)-1-benzofuran-3-carboxamide;5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-N-methyl-6-[methyl(methylsulfonyl)amino]-2-(4,5,6,7-tetrahydropyrazolo[1,5-a]pyridin-3-yl)-1-benzofuran-3-carboxamide with MolForge

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What is the IUPAC name of 2-(2-tert-butyl-1,3-thiazol-5-yl)-5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-N-methyl-6-[methyl(methylsulfonyl)amino]-1-benzofuran-3-carboxamide;2-cyclopropyl-5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-N-methyl-6-[methyl(methylsulfonyl)amino]-1-benzofuran-3-carboxamide;2-(5,6-dihydro-4H-pyrrolo[2,1-e]pyrazol-3-yl)-5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-N-methyl-6-[methyl(methylsulfonyl)amino]-1-benzofuran-3-carboxamide;5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-N-methyl-6-[methyl(methylsulfonyl)amino]-2-(1-phenylpyrazol-4-yl)-1-benzofuran-3-carboxamide;5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-N-methyl-6-[methyl(methylsulfonyl)amino]-2-(1-propan-2-ylpyrrol-2-yl)-1-benzofuran-3-carboxamide;5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-N-methyl-6-[methyl(methylsulfonyl)amino]-2-(2-pyrrolidin-1-yl-1,3-thiazol-5-yl)-1-benzofuran-3-carboxamide;5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-N-methyl-6-[methyl(methylsulfonyl)amino]-2-(4,5,6,7-tetrahydropyrazolo[1,5-a]pyridin-3-yl)-1-benzofuran-3-carboxamide?
The IUPAC name of 2-(2-tert-butyl-1,3-thiazol-5-yl)-5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-N-methyl-6-[methyl(methylsulfonyl)amino]-1-benzofuran-3-carboxamide;2-cyclopropyl-5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-N-methyl-6-[methyl(methylsulfonyl)amino]-1-benzofuran-3-carboxamide;2-(5,6-dihydro-4H-pyrrolo[2,1-e]pyrazol-3-yl)-5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-N-methyl-6-[methyl(methylsulfonyl)amino]-1-benzofuran-3-carboxamide;5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-N-methyl-6-[methyl(methylsulfonyl)amino]-2-(1-phenylpyrazol-4-yl)-1-benzofuran-3-carboxamide;5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-N-methyl-6-[methyl(methylsulfonyl)amino]-2-(1-propan-2-ylpyrrol-2-yl)-1-benzofuran-3-carboxamide;5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-N-methyl-6-[methyl(methylsulfonyl)amino]-2-(2-pyrrolidin-1-yl-1,3-thiazol-5-yl)-1-benzofuran-3-carboxamide;5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-N-methyl-6-[methyl(methylsulfonyl)amino]-2-(4,5,6,7-tetrahydropyrazolo[1,5-a]pyridin-3-yl)-1-benzofuran-3-carboxamide (CID 159500408) is 2-(2-tert-butyl-1,3-thiazol-5-yl)-5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-N-methyl-6-[methyl(methylsulfonyl)amino]-1-benzofuran-3-carboxamide;2-cyclopropyl-5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-N-methyl-6-[methyl(methylsulfonyl)amino]-1-benzofuran-3-carboxamide;2-(5,6-dihydro-4H-pyrrolo[2,1-e]pyrazol-3-yl)-5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-N-methyl-6-[methyl(methylsulfonyl)amino]-1-benzofuran-3-carboxamide;5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-N-methyl-6-[methyl(methylsulfonyl)amino]-2-(1-phenylpyrazol-4-yl)-1-benzofuran-3-carboxamide;5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-N-methyl-6-[methyl(methylsulfonyl)amino]-2-(1-propan-2-ylpyrrol-2-yl)-1-benzofuran-3-carboxamide;5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-N-methyl-6-[methyl(methylsulfonyl)amino]-2-(2-pyrrolidin-1-yl-1,3-thiazol-5-yl)-1-benzofuran-3-carboxamide;5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-N-methyl-6-[methyl(methylsulfonyl)amino]-2-(4,5,6,7-tetrahydropyrazolo[1,5-a]pyridin-3-yl)-1-benzofuran-3-carboxamide.
What is the SMILES notation for 2-(2-tert-butyl-1,3-thiazol-5-yl)-5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-N-methyl-6-[methyl(methylsulfonyl)amino]-1-benzofuran-3-carboxamide;2-cyclopropyl-5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-N-methyl-6-[methyl(methylsulfonyl)amino]-1-benzofuran-3-carboxamide;2-(5,6-dihydro-4H-pyrrolo[2,1-e]pyrazol-3-yl)-5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-N-methyl-6-[methyl(methylsulfonyl)amino]-1-benzofuran-3-carboxamide;5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-N-methyl-6-[methyl(methylsulfonyl)amino]-2-(1-phenylpyrazol-4-yl)-1-benzofuran-3-carboxamide;5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-N-methyl-6-[methyl(methylsulfonyl)amino]-2-(1-propan-2-ylpyrrol-2-yl)-1-benzofuran-3-carboxamide;5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-N-methyl-6-[methyl(methylsulfonyl)amino]-2-(2-pyrrolidin-1-yl-1,3-thiazol-5-yl)-1-benzofuran-3-carboxamide;5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-N-methyl-6-[methyl(methylsulfonyl)amino]-2-(4,5,6,7-tetrahydropyrazolo[1,5-a]pyridin-3-yl)-1-benzofuran-3-carboxamide?
The canonical SMILES for 2-(2-tert-butyl-1,3-thiazol-5-yl)-5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-N-methyl-6-[methyl(methylsulfonyl)amino]-1-benzofuran-3-carboxamide;2-cyclopropyl-5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-N-methyl-6-[methyl(methylsulfonyl)amino]-1-benzofuran-3-carboxamide;2-(5,6-dihydro-4H-pyrrolo[2,1-e]pyrazol-3-yl)-5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-N-methyl-6-[methyl(methylsulfonyl)amino]-1-benzofuran-3-carboxamide;5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-N-methyl-6-[methyl(methylsulfonyl)amino]-2-(1-phenylpyrazol-4-yl)-1-benzofuran-3-carboxamide;5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-N-methyl-6-[methyl(methylsulfonyl)amino]-2-(1-propan-2-ylpyrrol-2-yl)-1-benzofuran-3-carboxamide;5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-N-methyl-6-[methyl(methylsulfonyl)amino]-2-(2-pyrrolidin-1-yl-1,3-thiazol-5-yl)-1-benzofuran-3-carboxamide;5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-N-methyl-6-[methyl(methylsulfonyl)amino]-2-(4,5,6,7-tetrahydropyrazolo[1,5-a]pyridin-3-yl)-1-benzofuran-3-carboxamide is CNC(=O)c1c(-c2cccn2C(C)C)oc2cc(N(C)S(C)(=O)=O)c(-c3ccc4c(n3)-c3cc5c(F)cccc5n3CC4)cc12.CNC(=O)c1c(-c2cnc(C(C)(C)C)s2)oc2cc(N(C)S(C)(=O)=O)c(-c3ccc4c(n3)-c3cc5c(F)cccc5n3CC4)cc12.CNC(=O)c1c(-c2cnc(N3CCCC3)s2)oc2cc(N(C)S(C)(=O)=O)c(-c3ccc4c(n3)-c3cc5c(F)cccc5n3CC4)cc12.CNC(=O)c1c(-c2cnn(-c3ccccc3)c2)oc2cc(N(C)S(C)(=O)=O)c(-c3ccc4c(n3)-c3cc5c(F)cccc5n3CC4)cc12.CNC(=O)c1c(-c2cnn3c2CCC3)oc2cc(N(C)S(C)(=O)=O)c(-c3ccc4c(n3)-c3cc5c(F)cccc5n3CC4)cc12.CNC(=O)c1c(-c2cnn3c2CCCC3)oc2cc(N(C)S(C)(=O)=O)c(-c3ccc4c(n3)-c3cc5c(F)cccc5n3CC4)cc12.CNC(=O)c1c(C2CC2)oc2cc(N(C)S(C)(=O)=O)c(-c3ccc4c(n3)-c3cc5c(F)cccc5n3CC4)cc12.
What is the InChIKey of 2-(2-tert-butyl-1,3-thiazol-5-yl)-5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-N-methyl-6-[methyl(methylsulfonyl)amino]-1-benzofuran-3-carboxamide;2-cyclopropyl-5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-N-methyl-6-[methyl(methylsulfonyl)amino]-1-benzofuran-3-carboxamide;2-(5,6-dihydro-4H-pyrrolo[2,1-e]pyrazol-3-yl)-5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-N-methyl-6-[methyl(methylsulfonyl)amino]-1-benzofuran-3-carboxamide;5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-N-methyl-6-[methyl(methylsulfonyl)amino]-2-(1-phenylpyrazol-4-yl)-1-benzofuran-3-carboxamide;5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-N-methyl-6-[methyl(methylsulfonyl)amino]-2-(1-propan-2-ylpyrrol-2-yl)-1-benzofuran-3-carboxamide;5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-N-methyl-6-[methyl(methylsulfonyl)amino]-2-(2-pyrrolidin-1-yl-1,3-thiazol-5-yl)-1-benzofuran-3-carboxamide;5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-N-methyl-6-[methyl(methylsulfonyl)amino]-2-(4,5,6,7-tetrahydropyrazolo[1,5-a]pyridin-3-yl)-1-benzofuran-3-carboxamide?
The InChIKey is LZHVCYHIWTTZHM-UHFFFAOYSA-N. The full InChI is InChI=1S/C36H29FN6O4S.C34H31FN6O4S2.C34H31FN6O4S.C34H32FN5O4S2.C34H32FN5O4S.C33H29FN6O4S.C30H27FN4O4S/c1-38-36(44)33-26-16-25(28-13-12-21-14-15-42-29-11-7-10-27(37)24(29)17-31(42)34(21)40-28)30(41(2)48(3,45)46)18-32(26)47-35(33)22-19-39-43(20-22)23-8-5-4-6-9-23;1-36-33(42)30-22-15-21(24-10-9-19-11-14-41-25-8-6-7-23(35)20(25)16-27(41)31(19)38-24)26(39(2)47(3,43)44)17-28(22)45-32(30)29-18-37-34(46-29)40-12-4-5-13-40;1-36-34(42)31-22-15-21(25-11-10-19-12-14-40-26-9-6-7-24(35)20(26)16-29(40)32(19)38-25)28(39(2)46(3,43)44)17-30(22)45-33(31)23-18-37-41-13-5-4-8-27(23)41;1-34(2,3)33-37-17-28(45-33)31-29(32(41)36-4)21-14-20(25(16-27(21)44-31)39(5)46(6,42)43)23-11-10-18-12-13-40-24-9-7-8-22(35)19(24)15-26(40)30(18)38-23;1-19(2)39-14-7-10-27(39)33-31(34(41)36-3)23-16-22(28(18-30(23)44-33)38(4)45(5,42)43)25-12-11-20-13-15-40-26-9-6-8-24(35)21(26)17-29(40)32(20)37-25;1-35-33(41)30-21-14-20(24-10-9-18-11-13-39-25-7-4-6-23(34)19(25)15-28(39)31(18)37-24)27(38(2)45(3,42)43)16-29(21)44-32(30)22-17-36-40-12-5-8-26(22)40;1-32-30(36)27-20-13-19(24(34(2)40(3,37)38)15-26(20)39-29(27)17-7-8-17)22-10-9-16-11-12-35-23-6-4-5-21(31)18(23)14-25(35)28(16)33-22/h4-13,16-20H,14-15H2,1-3H3,(H,38,44);6-10,15-18H,4-5,11-14H2,1-3H3,(H,36,42);6-7,9-11,15-18H,4-5,8,12-14H2,1-3H3,(H,36,42);7-11,14-17H,12-13H2,1-6H3,(H,36,41);6-12,14,16-19H,13,15H2,1-5H3,(H,36,41);4,6-7,9-10,14-17H,5,8,11-13H2,1-3H3,(H,35,41);4-6,9-10,13-15,17H,7-8,11-12H2,1-3H3,(H,32,36).
What are the key properties of 2-(2-tert-butyl-1,3-thiazol-5-yl)-5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-N-methyl-6-[methyl(methylsulfonyl)amino]-1-benzofuran-3-carboxamide;2-cyclopropyl-5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-N-methyl-6-[methyl(methylsulfonyl)amino]-1-benzofuran-3-carboxamide;2-(5,6-dihydro-4H-pyrrolo[2,1-e]pyrazol-3-yl)-5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-N-methyl-6-[methyl(methylsulfonyl)amino]-1-benzofuran-3-carboxamide;5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-N-methyl-6-[methyl(methylsulfonyl)amino]-2-(1-phenylpyrazol-4-yl)-1-benzofuran-3-carboxamide;5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-N-methyl-6-[methyl(methylsulfonyl)amino]-2-(1-propan-2-ylpyrrol-2-yl)-1-benzofuran-3-carboxamide;5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-N-methyl-6-[methyl(methylsulfonyl)amino]-2-(2-pyrrolidin-1-yl-1,3-thiazol-5-yl)-1-benzofuran-3-carboxamide;5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-N-methyl-6-[methyl(methylsulfonyl)amino]-2-(4,5,6,7-tetrahydropyrazolo[1,5-a]pyridin-3-yl)-1-benzofuran-3-carboxamide?
2-(2-tert-butyl-1,3-thiazol-5-yl)-5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-N-methyl-6-[methyl(methylsulfonyl)amino]-1-benzofuran-3-carboxamide;2-cyclopropyl-5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-N-methyl-6-[methyl(methylsulfonyl)amino]-1-benzofuran-3-carboxamide;2-(5,6-dihydro-4H-pyrrolo[2,1-e]pyrazol-3-yl)-5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-N-methyl-6-[methyl(methylsulfonyl)amino]-1-benzofuran-3-carboxamide;5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-N-methyl-6-[methyl(methylsulfonyl)amino]-2-(1-phenylpyrazol-4-yl)-1-benzofuran-3-carboxamide;5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-N-methyl-6-[methyl(methylsulfonyl)amino]-2-(1-propan-2-ylpyrrol-2-yl)-1-benzofuran-3-carboxamide;5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-N-methyl-6-[methyl(methylsulfonyl)amino]-2-(2-pyrrolidin-1-yl-1,3-thiazol-5-yl)-1-benzofuran-3-carboxamide;5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-N-methyl-6-[methyl(methylsulfonyl)amino]-2-(4,5,6,7-tetrahydropyrazolo[1,5-a]pyridin-3-yl)-1-benzofuran-3-carboxamide has a molecular weight of 4437.10 g/mol, XLogP of 42.90, 38 rotatable bonds, 7 hydrogen bond donors, and 54 hydrogen bond acceptors.
Where does this data come from?
All data for 2-(2-tert-butyl-1,3-thiazol-5-yl)-5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-N-methyl-6-[methyl(methylsulfonyl)amino]-1-benzofuran-3-carboxamide;2-cyclopropyl-5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-N-methyl-6-[methyl(methylsulfonyl)amino]-1-benzofuran-3-carboxamide;2-(5,6-dihydro-4H-pyrrolo[2,1-e]pyrazol-3-yl)-5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-N-methyl-6-[methyl(methylsulfonyl)amino]-1-benzofuran-3-carboxamide;5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-N-methyl-6-[methyl(methylsulfonyl)amino]-2-(1-phenylpyrazol-4-yl)-1-benzofuran-3-carboxamide;5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-N-methyl-6-[methyl(methylsulfonyl)amino]-2-(1-propan-2-ylpyrrol-2-yl)-1-benzofuran-3-carboxamide;5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-N-methyl-6-[methyl(methylsulfonyl)amino]-2-(2-pyrrolidin-1-yl-1,3-thiazol-5-yl)-1-benzofuran-3-carboxamide;5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-N-methyl-6-[methyl(methylsulfonyl)amino]-2-(4,5,6,7-tetrahydropyrazolo[1,5-a]pyridin-3-yl)-1-benzofuran-3-carboxamide is sourced from PubChem (CID 159500408), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).