7-[1-[3-(3,3-difluoroazetidin-1-yl)propyl]pyrazol-4-yl]-N-(5-propan-2-ylpyridazin-3-yl)-1,5-naphthyridin-2-amine;7-[1-[3-[(2R,6S)-2,6-dimethylmorpholin-4-yl]propyl]pyrazol-4-yl]-N-(5-propan-2-ylpyridazin-3-yl)-1,5-naphthyridin-2-amine;N,N-dimethyl-1-[3-[4-[6-[(5-propan-2-ylpyridazin-3-yl)amino]-1,5-naphthyridin-3-yl]pyrazol-1-yl]propyl]azetidine-3-carboxamide;7-[1-[3-(3-isocyanoazetidin-1-yl)propyl]pyrazol-4-yl]-N-(5-propan-2-ylpyridazin-3-yl)-1,5-naphthyridin-2-amine;7-[1-[3-(3-methoxyazetidin-1-yl)propyl]pyrazol-4-yl]-N-(5-propan-2-ylpyridazin-3-yl)-1,5-naphthyridin-2-amine

C128H150F2N42O3 — CID 159539628

About 7-[1-[3-(3,3-difluoroazetidin-1-yl)propyl]pyrazol-4-yl]-N-(5-propan-2-ylpyridazin-3-yl)-1,5-naphthyridin-2-amine;7-[1-[3-[(2R,6S)-2,6-dimethylmorpholin-4-yl]propyl]pyrazol-4-yl]-N-(5-propan-2-ylpyridazin-3-yl)-1,5-naphthyridin-2-amine;N,N-dimethyl-1-[3-[4-[6-[(5-propan-2-ylpyridazin-3-yl)amino]-1,5-naphthyridin-3-yl]pyrazol-1-yl]propyl]azetidine-3-carboxamide;7-[1-[3-(3-isocyanoazetidin-1-yl)propyl]pyrazol-4-yl]-N-(5-propan-2-ylpyridazin-3-yl)-1,5-naphthyridin-2-amine;7-[1-[3-(3-methoxyazetidin-1-yl)propyl]pyrazol-4-yl]-N-(5-propan-2-ylpyridazin-3-yl)-1,5-naphthyridin-2-amine

7-[1-[3-(3,3-difluoroazetidin-1-yl)propyl]pyrazol-4-yl]-N-(5-propan-2-ylpyridazin-3-yl)-1,5-naphthyridin-2-amine;7-[1-[3-[(2R,6S)-2,6-dimethylmorpholin-4-yl]propyl]pyrazol-4-yl]-N-(5-propan-2-ylpyridazin-3-yl)-1,5-naphthyridin-2-amine;N,N-dimethyl-1-[3-[4-[6-[(5-propan-2-ylpyridazin-3-yl)amino]-1,5-naphthyridin-3-yl]pyrazol-1-yl]propyl]azetidine-3-carboxamide;7-[1-[3-(3-isocyanoazetidin-1-yl)propyl]pyrazol-4-yl]-N-(5-propan-2-ylpyridazin-3-yl)-1,5-naphthyridin-2-amine;7-[1-[3-(3-methoxyazetidin-1-yl)propyl]pyrazol-4-yl]-N-(5-propan-2-ylpyridazin-3-yl)-1,5-naphthyridin-2-amine (PubChem CID 159539628) has the molecular formula C128H150F2N42O3 and a molecular weight of 2362.89 g/mol. Its IUPAC name is 7-[1-[3-(3,3-difluoroazetidin-1-yl)propyl]pyrazol-4-yl]-N-(5-propan-2-ylpyridazin-3-yl)-1,5-naphthyridin-2-amine;7-[1-[3-[(2R,6S)-2,6-dimethylmorpholin-4-yl]propyl]pyrazol-4-yl]-N-(5-propan-2-ylpyridazin-3-yl)-1,5-naphthyridin-2-amine;N,N-dimethyl-1-[3-[4-[6-[(5-propan-2-ylpyridazin-3-yl)amino]-1,5-naphthyridin-3-yl]pyrazol-1-yl]propyl]azetidine-3-carboxamide;7-[1-[3-(3-isocyanoazetidin-1-yl)propyl]pyrazol-4-yl]-N-(5-propan-2-ylpyridazin-3-yl)-1,5-naphthyridin-2-amine;7-[1-[3-(3-methoxyazetidin-1-yl)propyl]pyrazol-4-yl]-N-(5-propan-2-ylpyridazin-3-yl)-1,5-naphthyridin-2-amine.

Molecular Properties

• Compound Name: 7-[1-[3-(3,3-difluoroazetidin-1-yl)propyl]pyrazol-4-yl]-N-(5-propan-2-ylpyridazin-3-yl)-1,5-naphthyridin-2-amine;7-[1-[3-[(2R,6S)-2,6-dimethylmorpholin-4-yl]propyl]pyrazol-4-yl]-N-(5-propan-2-ylpyridazin-3-yl)-1,5-naphthyridin-2-amine;N,N-dimethyl-1-[3-[4-[6-[(5-propan-2-ylpyridazin-3-yl)amino]-1,5-naphthyridin-3-yl]pyrazol-1-yl]propyl]azetidine-3-carboxamide;7-[1-[3-(3-isocyanoazetidin-1-yl)propyl]pyrazol-4-yl]-N-(5-propan-2-ylpyridazin-3-yl)-1,5-naphthyridin-2-amine;7-[1-[3-(3-methoxyazetidin-1-yl)propyl]pyrazol-4-yl]-N-(5-propan-2-ylpyridazin-3-yl)-1,5-naphthyridin-2-amine
• PubChem CID: 159539628
• Molecular Formula: C128H150F2N42O3
• Molecular Weight: 2362.89 g/mol
• Exact Mass: 2361.28
• IUPAC Name: 7-[1-[3-(3,3-difluoroazetidin-1-yl)propyl]pyrazol-4-yl]-N-(5-propan-2-ylpyridazin-3-yl)-1,5-naphthyridin-2-amine;7-[1-[3-[(2R,6S)-2,6-dimethylmorpholin-4-yl]propyl]pyrazol-4-yl]-N-(5-propan-2-ylpyridazin-3-yl)-1,5-naphthyridin-2-amine;N,N-dimethyl-1-[3-[4-[6-[(5-propan-2-ylpyridazin-3-yl)amino]-1,5-naphthyridin-3-yl]pyrazol-1-yl]propyl]azetidine-3-carboxamide;7-[1-[3-(3-isocyanoazetidin-1-yl)propyl]pyrazol-4-yl]-N-(5-propan-2-ylpyridazin-3-yl)-1,5-naphthyridin-2-amine;7-[1-[3-(3-methoxyazetidin-1-yl)propyl]pyrazol-4-yl]-N-(5-propan-2-ylpyridazin-3-yl)-1,5-naphthyridin-2-amine
• SMILES: CC(C)c1cnnc(Nc2ccc3ncc(-c4cnn(CCCN5CC(C(=O)N(C)C)C5)c4)cc3n2)c1.CC(C)c1cnnc(Nc2ccc3ncc(-c4cnn(CCCN5CC(F)(F)C5)c4)cc3n2)c1.CC(C)c1cnnc(Nc2ccc3ncc(-c4cnn(CCCN5C[C@@H](C)O[C@@H](C)C5)c4)cc3n2)c1.COC1CN(CCCn2cc(-c3cnc4ccc(Nc5cc(C(C)C)cnn5)nc4c3)cn2)C1.[C-]#[N+]C1CN(CCCn2cc(-c3cnc4ccc(Nc5cc(C(C)C)cnn5)nc4c3)cn2)C1
• InChI: InChI=1S/C27H33N9O.C27H34N8O.C25H27N9.C25H30N8O.C24H26F2N8/c1-18(2)19-11-26(33-29-13-19)32-25-7-6-23-24(31-25)10-20(12-28-23)21-14-30-36(17-21)9-5-8-35-15-22(16-35)27(37)34(3)4;1-18(2)21-11-27(33-29-13-21)32-26-7-6-24-25(31-26)10-22(12-28-24)23-14-30-35(17-23)9-5-8-34-15-19(3)36-20(4)16-34;1-17(2)18-10-25(32-28-12-18)31-24-6-5-22-23(30-24)9-19(11-27-22)20-13-29-34(14-20)8-4-7-33-15-21(16-33)26-3;1-17(2)18-10-25(31-27-12-18)30-24-6-5-22-23(29-24)9-19(11-26-22)20-13-28-33(14-20)8-4-7-32-15-21(16-32)34-3;1-16(2)17-9-23(32-28-11-17)31-22-5-4-20-21(30-22)8-18(10-27-20)19-12-29-34(13-19)7-3-6-33-14-24(25,26)15-33/h6-7,10-14,17-18,22H,5,8-9,15-16H2,1-4H3,(H,31,32,33);6-7,10-14,17-20H,5,8-9,15-16H2,1-4H3,(H,31,32,33);5-6,9-14,17,21H,4,7-8,15-16H2,1-2H3,(H,30,31,32);5-6,9-14,17,21H,4,7-8,15-16H2,1-3H3,(H,29,30,31);4-5,8-13,16H,3,6-7,14-15H2,1-2H3,(H,30,31,32)/t;19-,20+
• InChIKey: MEAOFLPMXBEEEA-KCZQTPGJSA-N
• XLogP: 20.72
• TPSA: 466.38 Ų
• H-Bond Donors: 5
• H-Bond Acceptors: 43
• Rotatable Bonds: 42
• Heavy Atoms: 175
• Complexity: —

Lipinski Rule of Five

3 violations

Rule	Value
MW ≤ 500	2362.89
LogP ≤ 5	20.72
H-Bond Donors ≤ 5	5
H-Bond Acceptors ≤ 10	43

Computed Properties (RDKit)

• Structural Alerts: {'alert_name': 'Carbo_cation/anion', 'substructure': 'N/A'}

Frequently Asked Questions

What is the IUPAC name of 7-[1-[3-(3,3-difluoroazetidin-1-yl)propyl]pyrazol-4-yl]-N-(5-propan-2-ylpyridazin-3-yl)-1,5-naphthyridin-2-amine;7-[1-[3-[(2R,6S)-2,6-dimethylmorpholin-4-yl]propyl]pyrazol-4-yl]-N-(5-propan-2-ylpyridazin-3-yl)-1,5-naphthyridin-2-amine;N,N-dimethyl-1-[3-[4-[6-[(5-propan-2-ylpyridazin-3-yl)amino]-1,5-naphthyridin-3-yl]pyrazol-1-yl]propyl]azetidine-3-carboxamide;7-[1-[3-(3-isocyanoazetidin-1-yl)propyl]pyrazol-4-yl]-N-(5-propan-2-ylpyridazin-3-yl)-1,5-naphthyridin-2-amine;7-[1-[3-(3-methoxyazetidin-1-yl)propyl]pyrazol-4-yl]-N-(5-propan-2-ylpyridazin-3-yl)-1,5-naphthyridin-2-amine?

The IUPAC name of 7-[1-[3-(3,3-difluoroazetidin-1-yl)propyl]pyrazol-4-yl]-N-(5-propan-2-ylpyridazin-3-yl)-1,5-naphthyridin-2-amine;7-[1-[3-[(2R,6S)-2,6-dimethylmorpholin-4-yl]propyl]pyrazol-4-yl]-N-(5-propan-2-ylpyridazin-3-yl)-1,5-naphthyridin-2-amine;N,N-dimethyl-1-[3-[4-[6-[(5-propan-2-ylpyridazin-3-yl)amino]-1,5-naphthyridin-3-yl]pyrazol-1-yl]propyl]azetidine-3-carboxamide;7-[1-[3-(3-isocyanoazetidin-1-yl)propyl]pyrazol-4-yl]-N-(5-propan-2-ylpyridazin-3-yl)-1,5-naphthyridin-2-amine;7-[1-[3-(3-methoxyazetidin-1-yl)propyl]pyrazol-4-yl]-N-(5-propan-2-ylpyridazin-3-yl)-1,5-naphthyridin-2-amine (CID 159539628) is 7-[1-[3-(3,3-difluoroazetidin-1-yl)propyl]pyrazol-4-yl]-N-(5-propan-2-ylpyridazin-3-yl)-1,5-naphthyridin-2-amine;7-[1-[3-[(2R,6S)-2,6-dimethylmorpholin-4-yl]propyl]pyrazol-4-yl]-N-(5-propan-2-ylpyridazin-3-yl)-1,5-naphthyridin-2-amine;N,N-dimethyl-1-[3-[4-[6-[(5-propan-2-ylpyridazin-3-yl)amino]-1,5-naphthyridin-3-yl]pyrazol-1-yl]propyl]azetidine-3-carboxamide;7-[1-[3-(3-isocyanoazetidin-1-yl)propyl]pyrazol-4-yl]-N-(5-propan-2-ylpyridazin-3-yl)-1,5-naphthyridin-2-amine;7-[1-[3-(3-methoxyazetidin-1-yl)propyl]pyrazol-4-yl]-N-(5-propan-2-ylpyridazin-3-yl)-1,5-naphthyridin-2-amine.

What is the SMILES notation for 7-[1-[3-(3,3-difluoroazetidin-1-yl)propyl]pyrazol-4-yl]-N-(5-propan-2-ylpyridazin-3-yl)-1,5-naphthyridin-2-amine;7-[1-[3-[(2R,6S)-2,6-dimethylmorpholin-4-yl]propyl]pyrazol-4-yl]-N-(5-propan-2-ylpyridazin-3-yl)-1,5-naphthyridin-2-amine;N,N-dimethyl-1-[3-[4-[6-[(5-propan-2-ylpyridazin-3-yl)amino]-1,5-naphthyridin-3-yl]pyrazol-1-yl]propyl]azetidine-3-carboxamide;7-[1-[3-(3-isocyanoazetidin-1-yl)propyl]pyrazol-4-yl]-N-(5-propan-2-ylpyridazin-3-yl)-1,5-naphthyridin-2-amine;7-[1-[3-(3-methoxyazetidin-1-yl)propyl]pyrazol-4-yl]-N-(5-propan-2-ylpyridazin-3-yl)-1,5-naphthyridin-2-amine?

The canonical SMILES for 7-[1-[3-(3,3-difluoroazetidin-1-yl)propyl]pyrazol-4-yl]-N-(5-propan-2-ylpyridazin-3-yl)-1,5-naphthyridin-2-amine;7-[1-[3-[(2R,6S)-2,6-dimethylmorpholin-4-yl]propyl]pyrazol-4-yl]-N-(5-propan-2-ylpyridazin-3-yl)-1,5-naphthyridin-2-amine;N,N-dimethyl-1-[3-[4-[6-[(5-propan-2-ylpyridazin-3-yl)amino]-1,5-naphthyridin-3-yl]pyrazol-1-yl]propyl]azetidine-3-carboxamide;7-[1-[3-(3-isocyanoazetidin-1-yl)propyl]pyrazol-4-yl]-N-(5-propan-2-ylpyridazin-3-yl)-1,5-naphthyridin-2-amine;7-[1-[3-(3-methoxyazetidin-1-yl)propyl]pyrazol-4-yl]-N-(5-propan-2-ylpyridazin-3-yl)-1,5-naphthyridin-2-amine is CC(C)c1cnnc(Nc2ccc3ncc(-c4cnn(CCCN5CC(C(=O)N(C)C)C5)c4)cc3n2)c1.CC(C)c1cnnc(Nc2ccc3ncc(-c4cnn(CCCN5CC(F)(F)C5)c4)cc3n2)c1.CC(C)c1cnnc(Nc2ccc3ncc(-c4cnn(CCCN5C[C@@H](C)O[C@@H](C)C5)c4)cc3n2)c1.COC1CN(CCCn2cc(-c3cnc4ccc(Nc5cc(C(C)C)cnn5)nc4c3)cn2)C1.[C-]#[N+]C1CN(CCCn2cc(-c3cnc4ccc(Nc5cc(C(C)C)cnn5)nc4c3)cn2)C1.

What is the InChIKey of 7-[1-[3-(3,3-difluoroazetidin-1-yl)propyl]pyrazol-4-yl]-N-(5-propan-2-ylpyridazin-3-yl)-1,5-naphthyridin-2-amine;7-[1-[3-[(2R,6S)-2,6-dimethylmorpholin-4-yl]propyl]pyrazol-4-yl]-N-(5-propan-2-ylpyridazin-3-yl)-1,5-naphthyridin-2-amine;N,N-dimethyl-1-[3-[4-[6-[(5-propan-2-ylpyridazin-3-yl)amino]-1,5-naphthyridin-3-yl]pyrazol-1-yl]propyl]azetidine-3-carboxamide;7-[1-[3-(3-isocyanoazetidin-1-yl)propyl]pyrazol-4-yl]-N-(5-propan-2-ylpyridazin-3-yl)-1,5-naphthyridin-2-amine;7-[1-[3-(3-methoxyazetidin-1-yl)propyl]pyrazol-4-yl]-N-(5-propan-2-ylpyridazin-3-yl)-1,5-naphthyridin-2-amine?

The InChIKey is MEAOFLPMXBEEEA-KCZQTPGJSA-N. The full InChI is InChI=1S/C27H33N9O.C27H34N8O.C25H27N9.C25H30N8O.C24H26F2N8/c1-18(2)19-11-26(33-29-13-19)32-25-7-6-23-24(31-25)10-20(12-28-23)21-14-30-36(17-21)9-5-8-35-15-22(16-35)27(37)34(3)4;1-18(2)21-11-27(33-29-13-21)32-26-7-6-24-25(31-26)10-22(12-28-24)23-14-30-35(17-23)9-5-8-34-15-19(3)36-20(4)16-34;1-17(2)18-10-25(32-28-12-18)31-24-6-5-22-23(30-24)9-19(11-27-22)20-13-29-34(14-20)8-4-7-33-15-21(16-33)26-3;1-17(2)18-10-25(31-27-12-18)30-24-6-5-22-23(29-24)9-19(11-26-22)20-13-28-33(14-20)8-4-7-32-15-21(16-32)34-3;1-16(2)17-9-23(32-28-11-17)31-22-5-4-20-21(30-22)8-18(10-27-20)19-12-29-34(13-19)7-3-6-33-14-24(25,26)15-33/h6-7,10-14,17-18,22H,5,8-9,15-16H2,1-4H3,(H,31,32,33);6-7,10-14,17-20H,5,8-9,15-16H2,1-4H3,(H,31,32,33);5-6,9-14,17,21H,4,7-8,15-16H2,1-2H3,(H,30,31,32);5-6,9-14,17,21H,4,7-8,15-16H2,1-3H3,(H,29,30,31);4-5,8-13,16H,3,6-7,14-15H2,1-2H3,(H,30,31,32)/t;19-,20+;;;.

What are the key properties of 7-[1-[3-(3,3-difluoroazetidin-1-yl)propyl]pyrazol-4-yl]-N-(5-propan-2-ylpyridazin-3-yl)-1,5-naphthyridin-2-amine;7-[1-[3-[(2R,6S)-2,6-dimethylmorpholin-4-yl]propyl]pyrazol-4-yl]-N-(5-propan-2-ylpyridazin-3-yl)-1,5-naphthyridin-2-amine;N,N-dimethyl-1-[3-[4-[6-[(5-propan-2-ylpyridazin-3-yl)amino]-1,5-naphthyridin-3-yl]pyrazol-1-yl]propyl]azetidine-3-carboxamide;7-[1-[3-(3-isocyanoazetidin-1-yl)propyl]pyrazol-4-yl]-N-(5-propan-2-ylpyridazin-3-yl)-1,5-naphthyridin-2-amine;7-[1-[3-(3-methoxyazetidin-1-yl)propyl]pyrazol-4-yl]-N-(5-propan-2-ylpyridazin-3-yl)-1,5-naphthyridin-2-amine?

7-[1-[3-(3,3-difluoroazetidin-1-yl)propyl]pyrazol-4-yl]-N-(5-propan-2-ylpyridazin-3-yl)-1,5-naphthyridin-2-amine;7-[1-[3-[(2R,6S)-2,6-dimethylmorpholin-4-yl]propyl]pyrazol-4-yl]-N-(5-propan-2-ylpyridazin-3-yl)-1,5-naphthyridin-2-amine;N,N-dimethyl-1-[3-[4-[6-[(5-propan-2-ylpyridazin-3-yl)amino]-1,5-naphthyridin-3-yl]pyrazol-1-yl]propyl]azetidine-3-carboxamide;7-[1-[3-(3-isocyanoazetidin-1-yl)propyl]pyrazol-4-yl]-N-(5-propan-2-ylpyridazin-3-yl)-1,5-naphthyridin-2-amine;7-[1-[3-(3-methoxyazetidin-1-yl)propyl]pyrazol-4-yl]-N-(5-propan-2-ylpyridazin-3-yl)-1,5-naphthyridin-2-amine has a molecular weight of 2362.89 g/mol, XLogP of 20.72, 42 rotatable bonds, 5 hydrogen bond donors, and 43 hydrogen bond acceptors.

Where does this data come from?

All data for 7-[1-[3-(3,3-difluoroazetidin-1-yl)propyl]pyrazol-4-yl]-N-(5-propan-2-ylpyridazin-3-yl)-1,5-naphthyridin-2-amine;7-[1-[3-[(2R,6S)-2,6-dimethylmorpholin-4-yl]propyl]pyrazol-4-yl]-N-(5-propan-2-ylpyridazin-3-yl)-1,5-naphthyridin-2-amine;N,N-dimethyl-1-[3-[4-[6-[(5-propan-2-ylpyridazin-3-yl)amino]-1,5-naphthyridin-3-yl]pyrazol-1-yl]propyl]azetidine-3-carboxamide;7-[1-[3-(3-isocyanoazetidin-1-yl)propyl]pyrazol-4-yl]-N-(5-propan-2-ylpyridazin-3-yl)-1,5-naphthyridin-2-amine;7-[1-[3-(3-methoxyazetidin-1-yl)propyl]pyrazol-4-yl]-N-(5-propan-2-ylpyridazin-3-yl)-1,5-naphthyridin-2-amine is sourced from PubChem (CID 159539628), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).