2-[3-[(5S,10R)-8-amino-2-(cyclopropylmethyl)-7,10-dimethyl-6,6-dioxo-6λ6-thia-2,7,9-triazaspiro[4.5]dec-8-en-10-yl]-4-fluorophenyl]-1-(5-fluoro-2-pyridinyl)ethanone;2-[3-[(5S,10R)-8-amino-2-(3,3-difluorobutyl)-7,10-dimethyl-6,6-dioxo-6λ6-thia-2,7,9-triazaspiro[4.5]dec-8-en-10-yl]-4-fluorophenyl]-1-(5-fluoro-2-pyridinyl)ethanone;2-[3-[(5S,10R)-8-amino-7,10-dimethyl-6,6-dioxo-2-(3H-pyrrol-5-ylmethyl)-6λ6-thia-2,7,9-triazaspiro[4.5]dec-8-en-10-yl]-4-fluorophenyl]-1-(5-fluoro-2-pyridinyl)ethanone;2-[3-[(5S,10R)-8-amino-7,10-dimethyl-2-(1,3-oxazol-5-ylmethyl)-6,6-dioxo-6λ6-thia-2,7,9-triazaspiro[4.5]dec-8-en-10-yl]-4-fluorophenyl]-1-(5-fluoro-2-pyridinyl)ethanone;2-[3-[(5R,10R)-8-amino-2-ethyl-7,10-dimethyl-6,6-dioxo-6λ6-thia-2,7,9-triazaspiro[4.5]dec-8-en-10-yl]-4-fluorophenyl]-1-(5-methoxy-2-pyridinyl)ethanone;2-[3-[(5R,10R)-8-amino-2-ethylsulfonyl-7,10-dimethyl-6,6-dioxo-6λ6-thia-2,7,9-triazaspiro[4.5]dec-8-en-10-yl]-4-fluorophenyl]-1-(5-methoxy-2-pyridinyl)ethanone

C149H172F12N32O23S7 — CID 159568376

IUPAC2-[3-[(5S,10R)-8-amino-2-(cyclopropylmethyl)-7,10-dimethyl-6,6-dioxo-6λ6-thia-2,7,9-triazaspiro[4.5]dec-8-en-10-yl]-4-fluorophenyl]-1-(5-fluoro-2-pyridinyl)ethanone;2-[3-[(5S,10R)-8-amino-2-(3,3-difluorobutyl)-7,10-dimethyl-6,6-dioxo-6λ6-thia-2,7,9-triazaspiro[4.5]dec-8-en-10-yl]-4-fluorophenyl]-1-(5-fluoro-2-pyridinyl)ethanone;2-[3-[(5S,10R)-8-amino-7,10-dimethyl-6,6-dioxo-2-(3H-pyrrol-5-ylmethyl)-6λ6-thia-2,7,9-triazaspiro[4.5]dec-8-en-10-yl]-4-fluorophenyl]-1-(5-fluoro-2-pyridinyl)ethanone;2-[3-[(5S,10R)-8-amino-7,10-dimethyl-2-(1,3-oxazol-5-ylmethyl)-6,6-dioxo-6λ6-thia-2,7,9-triazaspiro[4.5]dec-8-en-10-yl]-4-fluorophenyl]-1-(5-fluoro-2-pyridinyl)ethanone;2-[3-[(5R,10R)-8-amino-2-ethyl-7,10-dimethyl-6,6-dioxo-6λ6-thia-2,7,9-triazaspiro[4.5]dec-8-en-10-yl]-4-fluorophenyl]-1-(5-methoxy-2-pyridinyl)ethanone;2-[3-[(5R,10R)-8-amino-2-ethylsulfonyl-7,10-dimethyl-6,6-dioxo-6λ6-thia-2,7,9-triazaspiro[4.5]dec-8-en-10-yl]-4-fluorophenyl]-1-(5-methoxy-2-pyridinyl)ethanone
SMILESCCN1CC[C@@]2(C1)[C@@](C)(c1cc(CC(=O)c3ccc(OC)cn3)ccc1F)N=C(N)N(C)S2(=O)=O.CCS(=O)(=O)N1CC[C@@]2(C1)[C@@](C)(c1cc(CC(=O)c3ccc(OC)cn3)ccc1F)N=C(N)N(C)S2(=O)=O.CN1C(N)=N[C@](C)(c2cc(CC(=O)c3ccc(F)cn3)ccc2F)[C@@]2(CCN(CC3=CCC=N3)C2)S1(=O)=O.CN1C(N)=N[C@](C)(c2cc(CC(=O)c3ccc(F)cn3)ccc2F)[C@@]2(CCN(CC3CC3)C2)S1(=O)=O.CN1C(N)=N[C@](C)(c2cc(CC(=O)c3ccc(F)cn3)ccc2F)[C@@]2(CCN(CCC(C)(F)F)C2)S1(=O)=O.CN1C(N)=N[C@](C)(c2cc(CC(=O)c3ccc(F)cn3)ccc2F)[C@@]2(CCN(Cc3cnco3)C2)S1(=O)=O
InChIInChI=1S/C26H28F2N6O3S.C25H29F4N5O3S.C25H26F2N6O4S.C25H29F2N5O3S.C24H30FN5O6S2.C24H30FN5O4S/c1-25(20-12-17(5-7-21(20)28)13-23(35)22-8-6-18(27)14-31-22)26(38(36,37)33(2)24(29)32-25)9-11-34(16-26)15-19-4-3-10-30-19;1-23(28,29)8-10-34-11-9-25(15-34)24(2,32-22(30)33(3)38(25,36)37)18-12-16(4-6-19(18)27)13-21(35)20-7-5-17(26)14-31-20;1-24(19-9-16(3-5-20(19)27)10-22(34)21-6-4-17(26)11-30-21)25(38(35,36)32(2)23(28)31-24)7-8-33(14-25)13-18-12-29-15-37-18;1-24(19-11-17(5-7-20(19)27)12-22(33)21-8-6-18(26)13-29-21)25(36(34,35)31(2)23(28)30-24)9-10-32(15-25)14-16-3-4-16;1-5-37(32,33)30-11-10-24(15-30)23(2,28-22(26)29(3)38(24,34)35)18-12-16(6-8-19(18)25)13-21(31)20-9-7-17(36-4)14-27-20;1-5-30-11-10-24(15-30)23(2,28-22(26)29(3)35(24,32)33)18-12-16(6-8-19(18)25)13-21(31)20-9-7-17(34-4)14-27-20/h4-8,10,12,14H,3,9,11,13,15-16H2,1-2H3,(H2,29,32);4-7,12,14H,8-11,13,15H2,1-3H3,(H2,30,32);3-6,9,11-12,15H,7-8,10,13-14H2,1-2H3,(H2,28,31);5-8,11,13,16H,3-4,9-10,12,14-15H2,1-2H3,(H2,28,30);6-9,12,14H,5,10-11,13,15H2,1-4H3,(H2,26,28);6-9,12,14H,5,10-11,13,15H2,1-4H3,(H2,26,28)/t25-,26+;3*24-,25+;2*23-,24-/m111111/s1
InChIKeyMHMMHJZIVBLKII-LYAWNDLTSA-N
MW3231.66 g/mol
LogP13.32
Rot. Bonds38

About 2-[3-[(5S,10R)-8-amino-2-(cyclopropylmethyl)-7,10-dimethyl-6,6-dioxo-6λ6-thia-2,7,9-triazaspiro[4.5]dec-8-en-10-yl]-4-fluorophenyl]-1-(5-fluoro-2-pyridinyl)ethanone;2-[3-[(5S,10R)-8-amino-2-(3,3-difluorobutyl)-7,10-dimethyl-6,6-dioxo-6λ6-thia-2,7,9-triazaspiro[4.5]dec-8-en-10-yl]-4-fluorophenyl]-1-(5-fluoro-2-pyridinyl)ethanone;2-[3-[(5S,10R)-8-amino-7,10-dimethyl-6,6-dioxo-2-(3H-pyrrol-5-ylmethyl)-6λ6-thia-2,7,9-triazaspiro[4.5]dec-8-en-10-yl]-4-fluorophenyl]-1-(5-fluoro-2-pyridinyl)ethanone;2-[3-[(5S,10R)-8-amino-7,10-dimethyl-2-(1,3-oxazol-5-ylmethyl)-6,6-dioxo-6λ6-thia-2,7,9-triazaspiro[4.5]dec-8-en-10-yl]-4-fluorophenyl]-1-(5-fluoro-2-pyridinyl)ethanone;2-[3-[(5R,10R)-8-amino-2-ethyl-7,10-dimethyl-6,6-dioxo-6λ6-thia-2,7,9-triazaspiro[4.5]dec-8-en-10-yl]-4-fluorophenyl]-1-(5-methoxy-2-pyridinyl)ethanone;2-[3-[(5R,10R)-8-amino-2-ethylsulfonyl-7,10-dimethyl-6,6-dioxo-6λ6-thia-2,7,9-triazaspiro[4.5]dec-8-en-10-yl]-4-fluorophenyl]-1-(5-methoxy-2-pyridinyl)ethanone

2-[3-[(5S,10R)-8-amino-2-(cyclopropylmethyl)-7,10-dimethyl-6,6-dioxo-6λ6-thia-2,7,9-triazaspiro[4.5]dec-8-en-10-yl]-4-fluorophenyl]-1-(5-fluoro-2-pyridinyl)ethanone;2-[3-[(5S,10R)-8-amino-2-(3,3-difluorobutyl)-7,10-dimethyl-6,6-dioxo-6λ6-thia-2,7,9-triazaspiro[4.5]dec-8-en-10-yl]-4-fluorophenyl]-1-(5-fluoro-2-pyridinyl)ethanone;2-[3-[(5S,10R)-8-amino-7,10-dimethyl-6,6-dioxo-2-(3H-pyrrol-5-ylmethyl)-6λ6-thia-2,7,9-triazaspiro[4.5]dec-8-en-10-yl]-4-fluorophenyl]-1-(5-fluoro-2-pyridinyl)ethanone;2-[3-[(5S,10R)-8-amino-7,10-dimethyl-2-(1,3-oxazol-5-ylmethyl)-6,6-dioxo-6λ6-thia-2,7,9-triazaspiro[4.5]dec-8-en-10-yl]-4-fluorophenyl]-1-(5-fluoro-2-pyridinyl)ethanone;2-[3-[(5R,10R)-8-amino-2-ethyl-7,10-dimethyl-6,6-dioxo-6λ6-thia-2,7,9-triazaspiro[4.5]dec-8-en-10-yl]-4-fluorophenyl]-1-(5-methoxy-2-pyridinyl)ethanone;2-[3-[(5R,10R)-8-amino-2-ethylsulfonyl-7,10-dimethyl-6,6-dioxo-6λ6-thia-2,7,9-triazaspiro[4.5]dec-8-en-10-yl]-4-fluorophenyl]-1-(5-methoxy-2-pyridinyl)ethanone (PubChem CID 159568376) has the molecular formula C149H172F12N32O23S7 and a molecular weight of 3231.66 g/mol. Its IUPAC name is 2-[3-[(5S,10R)-8-amino-2-(cyclopropylmethyl)-7,10-dimethyl-6,6-dioxo-6λ6-thia-2,7,9-triazaspiro[4.5]dec-8-en-10-yl]-4-fluorophenyl]-1-(5-fluoro-2-pyridinyl)ethanone;2-[3-[(5S,10R)-8-amino-2-(3,3-difluorobutyl)-7,10-dimethyl-6,6-dioxo-6λ6-thia-2,7,9-triazaspiro[4.5]dec-8-en-10-yl]-4-fluorophenyl]-1-(5-fluoro-2-pyridinyl)ethanone;2-[3-[(5S,10R)-8-amino-7,10-dimethyl-6,6-dioxo-2-(3H-pyrrol-5-ylmethyl)-6λ6-thia-2,7,9-triazaspiro[4.5]dec-8-en-10-yl]-4-fluorophenyl]-1-(5-fluoro-2-pyridinyl)ethanone;2-[3-[(5S,10R)-8-amino-7,10-dimethyl-2-(1,3-oxazol-5-ylmethyl)-6,6-dioxo-6λ6-thia-2,7,9-triazaspiro[4.5]dec-8-en-10-yl]-4-fluorophenyl]-1-(5-fluoro-2-pyridinyl)ethanone;2-[3-[(5R,10R)-8-amino-2-ethyl-7,10-dimethyl-6,6-dioxo-6λ6-thia-2,7,9-triazaspiro[4.5]dec-8-en-10-yl]-4-fluorophenyl]-1-(5-methoxy-2-pyridinyl)ethanone;2-[3-[(5R,10R)-8-amino-2-ethylsulfonyl-7,10-dimethyl-6,6-dioxo-6λ6-thia-2,7,9-triazaspiro[4.5]dec-8-en-10-yl]-4-fluorophenyl]-1-(5-methoxy-2-pyridinyl)ethanone.

Molecular Properties

Compound Name2-[3-[(5S,10R)-8-amino-2-(cyclopropylmethyl)-7,10-dimethyl-6,6-dioxo-6λ6-thia-2,7,9-triazaspiro[4.5]dec-8-en-10-yl]-4-fluorophenyl]-1-(5-fluoro-2-pyridinyl)ethanone;2-[3-[(5S,10R)-8-amino-2-(3,3-difluorobutyl)-7,10-dimethyl-6,6-dioxo-6λ6-thia-2,7,9-triazaspiro[4.5]dec-8-en-10-yl]-4-fluorophenyl]-1-(5-fluoro-2-pyridinyl)ethanone;2-[3-[(5S,10R)-8-amino-7,10-dimethyl-6,6-dioxo-2-(3H-pyrrol-5-ylmethyl)-6λ6-thia-2,7,9-triazaspiro[4.5]dec-8-en-10-yl]-4-fluorophenyl]-1-(5-fluoro-2-pyridinyl)ethanone;2-[3-[(5S,10R)-8-amino-7,10-dimethyl-2-(1,3-oxazol-5-ylmethyl)-6,6-dioxo-6λ6-thia-2,7,9-triazaspiro[4.5]dec-8-en-10-yl]-4-fluorophenyl]-1-(5-fluoro-2-pyridinyl)ethanone;2-[3-[(5R,10R)-8-amino-2-ethyl-7,10-dimethyl-6,6-dioxo-6λ6-thia-2,7,9-triazaspiro[4.5]dec-8-en-10-yl]-4-fluorophenyl]-1-(5-methoxy-2-pyridinyl)ethanone;2-[3-[(5R,10R)-8-amino-2-ethylsulfonyl-7,10-dimethyl-6,6-dioxo-6λ6-thia-2,7,9-triazaspiro[4.5]dec-8-en-10-yl]-4-fluorophenyl]-1-(5-methoxy-2-pyridinyl)ethanone
PubChem CID159568376
Molecular FormulaC149H172F12N32O23S7
Molecular Weight3231.66 g/mol
Exact Mass3229.11
IUPAC Name2-[3-[(5S,10R)-8-amino-2-(cyclopropylmethyl)-7,10-dimethyl-6,6-dioxo-6λ6-thia-2,7,9-triazaspiro[4.5]dec-8-en-10-yl]-4-fluorophenyl]-1-(5-fluoro-2-pyridinyl)ethanone;2-[3-[(5S,10R)-8-amino-2-(3,3-difluorobutyl)-7,10-dimethyl-6,6-dioxo-6λ6-thia-2,7,9-triazaspiro[4.5]dec-8-en-10-yl]-4-fluorophenyl]-1-(5-fluoro-2-pyridinyl)ethanone;2-[3-[(5S,10R)-8-amino-7,10-dimethyl-6,6-dioxo-2-(3H-pyrrol-5-ylmethyl)-6λ6-thia-2,7,9-triazaspiro[4.5]dec-8-en-10-yl]-4-fluorophenyl]-1-(5-fluoro-2-pyridinyl)ethanone;2-[3-[(5S,10R)-8-amino-7,10-dimethyl-2-(1,3-oxazol-5-ylmethyl)-6,6-dioxo-6λ6-thia-2,7,9-triazaspiro[4.5]dec-8-en-10-yl]-4-fluorophenyl]-1-(5-fluoro-2-pyridinyl)ethanone;2-[3-[(5R,10R)-8-amino-2-ethyl-7,10-dimethyl-6,6-dioxo-6λ6-thia-2,7,9-triazaspiro[4.5]dec-8-en-10-yl]-4-fluorophenyl]-1-(5-methoxy-2-pyridinyl)ethanone;2-[3-[(5R,10R)-8-amino-2-ethylsulfonyl-7,10-dimethyl-6,6-dioxo-6λ6-thia-2,7,9-triazaspiro[4.5]dec-8-en-10-yl]-4-fluorophenyl]-1-(5-methoxy-2-pyridinyl)ethanone
SMILESCCN1CC[C@@]2(C1)[C@@](C)(c1cc(CC(=O)c3ccc(OC)cn3)ccc1F)N=C(N)N(C)S2(=O)=O.CCS(=O)(=O)N1CC[C@@]2(C1)[C@@](C)(c1cc(CC(=O)c3ccc(OC)cn3)ccc1F)N=C(N)N(C)S2(=O)=O.CN1C(N)=N[C@](C)(c2cc(CC(=O)c3ccc(F)cn3)ccc2F)[C@@]2(CCN(CC3=CCC=N3)C2)S1(=O)=O.CN1C(N)=N[C@](C)(c2cc(CC(=O)c3ccc(F)cn3)ccc2F)[C@@]2(CCN(CC3CC3)C2)S1(=O)=O.CN1C(N)=N[C@](C)(c2cc(CC(=O)c3ccc(F)cn3)ccc2F)[C@@]2(CCN(CCC(C)(F)F)C2)S1(=O)=O.CN1C(N)=N[C@](C)(c2cc(CC(=O)c3ccc(F)cn3)ccc2F)[C@@]2(CCN(Cc3cnco3)C2)S1(=O)=O
InChIInChI=1S/C26H28F2N6O3S.C25H29F4N5O3S.C25H26F2N6O4S.C25H29F2N5O3S.C24H30FN5O6S2.C24H30FN5O4S/c1-25(20-12-17(5-7-21(20)28)13-23(35)22-8-6-18(27)14-31-22)26(38(36,37)33(2)24(29)32-25)9-11-34(16-26)15-19-4-3-10-30-19;1-23(28,29)8-10-34-11-9-25(15-34)24(2,32-22(30)33(3)38(25,36)37)18-12-16(4-6-19(18)27)13-21(35)20-7-5-17(26)14-31-20;1-24(19-9-16(3-5-20(19)27)10-22(34)21-6-4-17(26)11-30-21)25(38(35,36)32(2)23(28)31-24)7-8-33(14-25)13-18-12-29-15-37-18;1-24(19-11-17(5-7-20(19)27)12-22(33)21-8-6-18(26)13-29-21)25(36(34,35)31(2)23(28)30-24)9-10-32(15-25)14-16-3-4-16;1-5-37(32,33)30-11-10-24(15-30)23(2,28-22(26)29(3)38(24,34)35)18-12-16(6-8-19(18)25)13-21(31)20-9-7-17(36-4)14-27-20;1-5-30-11-10-24(15-30)23(2,28-22(26)29(3)35(24,32)33)18-12-16(6-8-19(18)25)13-21(31)20-9-7-17(34-4)14-27-20/h4-8,10,12,14H,3,9,11,13,15-16H2,1-2H3,(H2,29,32);4-7,12,14H,8-11,13,15H2,1-3H3,(H2,30,32);3-6,9,11-12,15H,7-8,10,13-14H2,1-2H3,(H2,28,31);5-8,11,13,16H,3-4,9-10,12,14-15H2,1-2H3,(H2,28,30);6-9,12,14H,5,10-11,13,15H2,1-4H3,(H2,26,28);6-9,12,14H,5,10-11,13,15H2,1-4H3,(H2,26,28)/t25-,26+;3*24-,25+;2*23-,24-/m111111/s1
InChIKeyMHMMHJZIVBLKII-LYAWNDLTSA-N
XLogP13.32
TPSA744.75 Ų
H-Bond Donors6
H-Bond Acceptors48
Rotatable Bonds38
Heavy Atoms223
Complexity—

Lipinski Rule of Five

4 violations

RuleValue
MW ≤ 5003231.66
LogP ≤ 513.32
H-Bond Donors ≤ 56
H-Bond Acceptors ≤ 1048

Analyze 2-[3-[(5S,10R)-8-amino-2-(cyclopropylmethyl)-7,10-dimethyl-6,6-dioxo-6λ6-thia-2,7,9-triazaspiro[4.5]dec-8-en-10-yl]-4-fluorophenyl]-1-(5-fluoro-2-pyridinyl)ethanone;2-[3-[(5S,10R)-8-amino-2-(3,3-difluorobutyl)-7,10-dimethyl-6,6-dioxo-6λ6-thia-2,7,9-triazaspiro[4.5]dec-8-en-10-yl]-4-fluorophenyl]-1-(5-fluoro-2-pyridinyl)ethanone;2-[3-[(5S,10R)-8-amino-7,10-dimethyl-6,6-dioxo-2-(3H-pyrrol-5-ylmethyl)-6λ6-thia-2,7,9-triazaspiro[4.5]dec-8-en-10-yl]-4-fluorophenyl]-1-(5-fluoro-2-pyridinyl)ethanone;2-[3-[(5S,10R)-8-amino-7,10-dimethyl-2-(1,3-oxazol-5-ylmethyl)-6,6-dioxo-6λ6-thia-2,7,9-triazaspiro[4.5]dec-8-en-10-yl]-4-fluorophenyl]-1-(5-fluoro-2-pyridinyl)ethanone;2-[3-[(5R,10R)-8-amino-2-ethyl-7,10-dimethyl-6,6-dioxo-6λ6-thia-2,7,9-triazaspiro[4.5]dec-8-en-10-yl]-4-fluorophenyl]-1-(5-methoxy-2-pyridinyl)ethanone;2-[3-[(5R,10R)-8-amino-2-ethylsulfonyl-7,10-dimethyl-6,6-dioxo-6λ6-thia-2,7,9-triazaspiro[4.5]dec-8-en-10-yl]-4-fluorophenyl]-1-(5-methoxy-2-pyridinyl)ethanone with MolForge

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Launch Full Analysis

Related Compounds

2-[3-[(5S,10R)-8-amino-2-(cyclopentylmethyl)-7,10-dimethyl-6,6-dioxo-6lambda6-thia-2,7,9-triazaspiro[4.5]dec-8-en-10-yl]-4-fluorophenyl]-1-(5-methoxy-2-pyridinyl)ethanone;2-[3-[(5S,10R)-8-amino-2-(3,3-difluorobutyl)-7,10-dimethyl-6,6-dioxo-6lambda6-thia-2,7,9-triazaspiro[4.5]dec-8-en-10-yl]-4-fluorophenyl]-1-(5-methoxy-2-pyridinyl)ethanone;2-[3-[(5S,10R)-8-amino-7,10-dimethyl-6,6-dioxo-2-(pyridin-3-ylmethyl)-6lambda6-thia-2,7,9-triazaspiro[4.5]dec-8-en-10-yl]-4-fluorophenyl]-1-(5-methoxy-2-pyridinyl)ethanone;bis(2-[3-[(5S,10R)-8-amino-7,10-dimethyl-6,6-dioxo-2-(3H-pyrrol-5-ylmethyl)-6lambda6-thia-2,7,9-triazaspiro[4.5]dec-8-en-10-yl]-4-fluorophenyl]-1-(5-methoxy-2-pyridinyl)ethanone);2-[3-[(5S,10R)-8-amino-7,10-dimethyl-2-[(1-methylpyrrol-3-yl)methyl]-6,6-dioxo-6lambda6-thia-2,7,9-triazaspiro[4.5]dec-8-en-10-yl]-4-fluorophenyl]-1-(5-methoxy-2-pyridinyl)ethanone
CID 158393693
CID 160614359
CID 160614359
CID 157161214
CID 157161214
2-[3-[(5S,10R)-8-amino-7,10-dimethyl-6,6-dioxo-2-(oxolan-2-ylmethylsulfonyl)-6lambda6-thia-2,7,9-triazaspiro[4.5]dec-8-en-10-yl]-4-fluorophenyl]-1-(5-methoxy-2-pyridinyl)ethanone;2-[3-[(5R,10R)-8-amino-7,10-dimethyl-6,6-dioxo-2-(oxolan-2-ylmethylsulfonyl)-6lambda6-thia-2,7,9-triazaspiro[4.5]dec-8-en-10-yl]-4-fluorophenyl]-1-(5-methoxy-2-pyridinyl)ethanone;2-[3-[(5S,10R)-8-amino-7,10-dimethyl-6,6-dioxo-2-(1H-pyrazol-4-ylsulfonyl)-6lambda6-thia-2,7,9-triazaspiro[4.5]dec-8-en-10-yl]-4-fluorophenyl]-1-(5-methoxy-2-pyridinyl)ethanone;2-[3-[(5R,10R)-8-amino-7,10-dimethyl-2-(1-methylpyrrol-3-yl)sulfonyl-6,6-dioxo-6lambda6-thia-2,7,9-triazaspiro[4.5]dec-8-en-10-yl]-4-fluorophenyl]-1-(5-methoxy-2-pyridinyl)ethanone
CID 157513988
2-[3-[(5S,10R)-8-amino-2-(benzenesulfonyl)-7,10-dimethyl-6,6-dioxo-6lambda6-thia-2,7,9-triazaspiro[4.5]dec-8-en-10-yl]-4-fluorophenyl]-1-(5-methoxy-2-pyridinyl)ethanone;2-[3-[(5S,10R)-8-amino-7,10-dimethyl-2-(2-methylpropylsulfonyl)-6,6-dioxo-6lambda6-thia-2,7,9-triazaspiro[4.5]dec-8-en-10-yl]-4-fluorophenyl]-1-(5-methoxy-2-pyridinyl)ethanone;2-[3-[(5R,10R)-8-amino-2-ethyl-7,10-dimethyl-6,6-dioxo-6lambda6-thia-2,7,9-triazaspiro[4.5]dec-8-en-10-yl]-4-fluorophenyl]-1-(5-fluoro-2-pyridinyl)ethanone;2-[3-[(5S,10R)-8-amino-2-ethyl-7,10-dimethyl-6,6-dioxo-6lambda6-thia-2,7,9-triazaspiro[4.5]dec-8-en-10-yl]-4-fluorophenyl]-1-(5-methoxy-2-pyridinyl)ethanone;2-[3-[(5S,10R)-8-amino-2-ethylsulfonyl-7,10-dimethyl-6,6-dioxo-6lambda6-thia-2,7,9-triazaspiro[4.5]dec-8-en-10-yl]-4-fluorophenyl]-1-(5-methoxy-2-pyridinyl)ethanone
CID 158131708
2-[3-[(5R,10R)-8-amino-2-(benzenesulfonyl)-7,10-dimethyl-6,6-dioxo-6lambda6-thia-2,7,9-triazaspiro[4.5]dec-8-en-10-yl]-4-fluorophenyl]-1-(5-methoxy-2-pyridinyl)ethanone;2-[3-[(5S,10R)-8-amino-2-(cyclopropylmethyl)-7,10-dimethyl-6,6-dioxo-6lambda6-thia-2,7,9-triazaspiro[4.5]dec-8-en-10-yl]-4-fluorophenyl]-1-(5-methoxy-2-pyridinyl)ethanone;2-[3-[(5R,10R)-8-amino-2-(cyclopropylmethyl)-7,10-dimethyl-6,6-dioxo-6lambda6-thia-2,7,9-triazaspiro[4.5]dec-8-en-10-yl]-4-fluorophenyl]-1-(5-methoxy-2-pyridinyl)ethanone;2-[3-[(5S,10R)-8-amino-7,10-dimethyl-2-(1-methylpyrrol-3-yl)sulfonyl-6,6-dioxo-6lambda6-thia-2,7,9-triazaspiro[4.5]dec-8-en-10-yl]-4-fluorophenyl]-1-(5-methoxy-2-pyridinyl)ethanone
CID 158430705
2-[3-[(5R,10R)-8-amino-7,10-dimethyl-2-(2-methylpropylsulfonyl)-6,6-dioxo-6lambda6-thia-2,7,9-triazaspiro[4.5]dec-8-en-10-yl]-4-fluorophenyl]-1-(5-fluoro-2-pyridinyl)ethanone;2-[3-[(5R,10R)-8-amino-2-ethylsulfonyl-7,10-dimethyl-6,6-dioxo-6lambda6-thia-2,7,9-triazaspiro[4.5]dec-8-en-10-yl]-4-fluorophenyl]-1-(5-fluoro-2-pyridinyl)ethanone;2-[3-[(5S,10R)-8-amino-2-ethylsulfonyl-7,10-dimethyl-6,6-dioxo-6lambda6-thia-2,7,9-triazaspiro[4.5]dec-8-en-10-yl]-4-fluorophenyl]-1-(5-methoxy-2-pyridinyl)ethanone;2-[3-[(5S,10R)-8-amino-2-(4-fluorophenyl)sulfonyl-7,10-dimethyl-6,6-dioxo-6lambda6-thia-2,7,9-triazaspiro[4.5]dec-8-en-10-yl]-4-fluorophenyl]-1-(5-methoxy-2-pyridinyl)ethanone
CID 159388169
2-[3-[(5R,10R)-8-amino-2-(cyclopropylmethyl)-7,10-dimethyl-6,6-dioxo-6lambda6-thia-2,7,9-triazaspiro[4.5]dec-8-en-10-yl]-4-fluorophenyl]-1-(5-methoxy-2-pyridinyl)ethanone;2-[3-[(5R,10R)-8-amino-7,10-dimethyl-6,6-dioxo-2-(pyridin-2-ylmethyl)-6lambda6-thia-2,7,9-triazaspiro[4.5]dec-8-en-10-yl]-4-fluorophenyl]-1-(5-methoxy-2-pyridinyl)ethanone;bis(2-[3-[(5R,10R)-8-amino-7,10-dimethyl-6,6-dioxo-2-(pyridin-3-ylmethyl)-6lambda6-thia-2,7,9-triazaspiro[4.5]dec-8-en-10-yl]-4-fluorophenyl]-1-(5-methoxy-2-pyridinyl)ethanone);2-[3-[(5R,10R)-8-amino-7,10-dimethyl-2-[(1-methylpyrrol-3-yl)methyl]-6,6-dioxo-6lambda6-thia-2,7,9-triazaspiro[4.5]dec-8-en-10-yl]-4-fluorophenyl]-1-(5-methoxy-2-pyridinyl)ethanone;2-[3-[(5R,10R)-8-amino-2-[(3-methoxycyclobutyl)methyl]-7,10-dimethyl-6,6-dioxo-6lambda6-thia-2,7,9-triazaspiro[4.5]dec-8-en-10-yl]-4-fluorophenyl]-1-(5-methoxy-2-pyridinyl)ethanone
CID 160182979
CID 160359328
CID 160359328
CID 160652561
CID 160652561
2-[3-[(8R)-10-amino-2,8-dimethyl-6,6-dioxo-6lambda6-thia-2,9-diazaspiro[4.5]dec-9-en-8-yl]-4-fluorophenyl]-1-(5-chloropyrazin-2-yl)ethanone;2-[3-[(8R)-10-amino-2,8-dimethyl-6,6-dioxo-6lambda6-thia-2,9-diazaspiro[4.5]dec-9-en-8-yl]-4-fluorophenyl]-1-[5-(difluoromethoxy)-2-pyridinyl]ethanone;2-[3-[(8R)-10-amino-2,8-dimethyl-6,6-dioxo-6lambda6-thia-2,9-diazaspiro[4.5]dec-9-en-8-yl]-4-fluorophenyl]-1-(5-fluoro-2-pyridinyl)ethanone;2-[3-[(8R)-10-amino-2,8-dimethyl-6,6-dioxo-6lambda6-thia-2,9-diazaspiro[4.5]dec-9-en-8-yl]-4-fluorophenyl]-1-(5-isocyano-2-pyridinyl)ethanone;2-[3-[(8R)-10-amino-2,8-dimethyl-6,6-dioxo-6lambda6-thia-2,9-diazaspiro[4.5]dec-9-en-8-yl]-4-fluorophenyl]-1-(5-methylpyrazin-2-yl)ethanone;bis(2-[3-[(8R)-10-amino-2,8-dimethyl-6,6-dioxo-6lambda6-thia-2,9-diazaspiro[4.5]dec-9-en-8-yl]-4-fluorophenyl]-1-(5-methyl-2-pyridinyl)ethanone)
CID 160713873
2-[3-[(5S,10R)-8-amino-2-butyl-7,10-dimethyl-6,6-dioxo-6lambda6-thia-2,7,9-triazaspiro[4.5]dec-8-en-10-yl]-4-fluorophenyl]-1-(5-fluoro-2-pyridinyl)ethanone;2-[3-[(5S,10R)-8-amino-7,10-dimethyl-6,6-dioxo-2-(pyridin-3-ylmethyl)-6lambda6-thia-2,7,9-triazaspiro[4.5]dec-8-en-10-yl]-4-fluorophenyl]-1-(5-fluoro-2-pyridinyl)ethanone;2-[3-[(5R,10R)-8-amino-7,10-dimethyl-2-(2-methylpropylsulfonyl)-6,6-dioxo-6lambda6-thia-2,7,9-triazaspiro[4.5]dec-8-en-10-yl]-4-fluorophenyl]-1-(5-methoxy-2-pyridinyl)ethanone;2-[3-[(5S,10R)-8-amino-7,10-dimethyl-2-[(1-methylpyrrol-3-yl)methyl]-6,6-dioxo-6lambda6-thia-2,7,9-triazaspiro[4.5]dec-8-en-10-yl]-4-fluorophenyl]-1-(5-fluoro-2-pyridinyl)ethanone;2-[3-[(5R,10R)-8-amino-2-(4-fluorophenyl)sulfonyl-7,10-dimethyl-6,6-dioxo-6lambda6-thia-2,7,9-triazaspiro[4.5]dec-8-en-10-yl]-4-fluorophenyl]-1-(5-methoxy-2-pyridinyl)ethanone
CID 162007019

Frequently Asked Questions

What is the IUPAC name of 2-[3-[(5S,10R)-8-amino-2-(cyclopropylmethyl)-7,10-dimethyl-6,6-dioxo-6λ6-thia-2,7,9-triazaspiro[4.5]dec-8-en-10-yl]-4-fluorophenyl]-1-(5-fluoro-2-pyridinyl)ethanone;2-[3-[(5S,10R)-8-amino-2-(3,3-difluorobutyl)-7,10-dimethyl-6,6-dioxo-6λ6-thia-2,7,9-triazaspiro[4.5]dec-8-en-10-yl]-4-fluorophenyl]-1-(5-fluoro-2-pyridinyl)ethanone;2-[3-[(5S,10R)-8-amino-7,10-dimethyl-6,6-dioxo-2-(3H-pyrrol-5-ylmethyl)-6λ6-thia-2,7,9-triazaspiro[4.5]dec-8-en-10-yl]-4-fluorophenyl]-1-(5-fluoro-2-pyridinyl)ethanone;2-[3-[(5S,10R)-8-amino-7,10-dimethyl-2-(1,3-oxazol-5-ylmethyl)-6,6-dioxo-6λ6-thia-2,7,9-triazaspiro[4.5]dec-8-en-10-yl]-4-fluorophenyl]-1-(5-fluoro-2-pyridinyl)ethanone;2-[3-[(5R,10R)-8-amino-2-ethyl-7,10-dimethyl-6,6-dioxo-6λ6-thia-2,7,9-triazaspiro[4.5]dec-8-en-10-yl]-4-fluorophenyl]-1-(5-methoxy-2-pyridinyl)ethanone;2-[3-[(5R,10R)-8-amino-2-ethylsulfonyl-7,10-dimethyl-6,6-dioxo-6λ6-thia-2,7,9-triazaspiro[4.5]dec-8-en-10-yl]-4-fluorophenyl]-1-(5-methoxy-2-pyridinyl)ethanone?
The IUPAC name of 2-[3-[(5S,10R)-8-amino-2-(cyclopropylmethyl)-7,10-dimethyl-6,6-dioxo-6λ6-thia-2,7,9-triazaspiro[4.5]dec-8-en-10-yl]-4-fluorophenyl]-1-(5-fluoro-2-pyridinyl)ethanone;2-[3-[(5S,10R)-8-amino-2-(3,3-difluorobutyl)-7,10-dimethyl-6,6-dioxo-6λ6-thia-2,7,9-triazaspiro[4.5]dec-8-en-10-yl]-4-fluorophenyl]-1-(5-fluoro-2-pyridinyl)ethanone;2-[3-[(5S,10R)-8-amino-7,10-dimethyl-6,6-dioxo-2-(3H-pyrrol-5-ylmethyl)-6λ6-thia-2,7,9-triazaspiro[4.5]dec-8-en-10-yl]-4-fluorophenyl]-1-(5-fluoro-2-pyridinyl)ethanone;2-[3-[(5S,10R)-8-amino-7,10-dimethyl-2-(1,3-oxazol-5-ylmethyl)-6,6-dioxo-6λ6-thia-2,7,9-triazaspiro[4.5]dec-8-en-10-yl]-4-fluorophenyl]-1-(5-fluoro-2-pyridinyl)ethanone;2-[3-[(5R,10R)-8-amino-2-ethyl-7,10-dimethyl-6,6-dioxo-6λ6-thia-2,7,9-triazaspiro[4.5]dec-8-en-10-yl]-4-fluorophenyl]-1-(5-methoxy-2-pyridinyl)ethanone;2-[3-[(5R,10R)-8-amino-2-ethylsulfonyl-7,10-dimethyl-6,6-dioxo-6λ6-thia-2,7,9-triazaspiro[4.5]dec-8-en-10-yl]-4-fluorophenyl]-1-(5-methoxy-2-pyridinyl)ethanone (CID 159568376) is 2-[3-[(5S,10R)-8-amino-2-(cyclopropylmethyl)-7,10-dimethyl-6,6-dioxo-6λ6-thia-2,7,9-triazaspiro[4.5]dec-8-en-10-yl]-4-fluorophenyl]-1-(5-fluoro-2-pyridinyl)ethanone;2-[3-[(5S,10R)-8-amino-2-(3,3-difluorobutyl)-7,10-dimethyl-6,6-dioxo-6λ6-thia-2,7,9-triazaspiro[4.5]dec-8-en-10-yl]-4-fluorophenyl]-1-(5-fluoro-2-pyridinyl)ethanone;2-[3-[(5S,10R)-8-amino-7,10-dimethyl-6,6-dioxo-2-(3H-pyrrol-5-ylmethyl)-6λ6-thia-2,7,9-triazaspiro[4.5]dec-8-en-10-yl]-4-fluorophenyl]-1-(5-fluoro-2-pyridinyl)ethanone;2-[3-[(5S,10R)-8-amino-7,10-dimethyl-2-(1,3-oxazol-5-ylmethyl)-6,6-dioxo-6λ6-thia-2,7,9-triazaspiro[4.5]dec-8-en-10-yl]-4-fluorophenyl]-1-(5-fluoro-2-pyridinyl)ethanone;2-[3-[(5R,10R)-8-amino-2-ethyl-7,10-dimethyl-6,6-dioxo-6λ6-thia-2,7,9-triazaspiro[4.5]dec-8-en-10-yl]-4-fluorophenyl]-1-(5-methoxy-2-pyridinyl)ethanone;2-[3-[(5R,10R)-8-amino-2-ethylsulfonyl-7,10-dimethyl-6,6-dioxo-6λ6-thia-2,7,9-triazaspiro[4.5]dec-8-en-10-yl]-4-fluorophenyl]-1-(5-methoxy-2-pyridinyl)ethanone.
What is the SMILES notation for 2-[3-[(5S,10R)-8-amino-2-(cyclopropylmethyl)-7,10-dimethyl-6,6-dioxo-6λ6-thia-2,7,9-triazaspiro[4.5]dec-8-en-10-yl]-4-fluorophenyl]-1-(5-fluoro-2-pyridinyl)ethanone;2-[3-[(5S,10R)-8-amino-2-(3,3-difluorobutyl)-7,10-dimethyl-6,6-dioxo-6λ6-thia-2,7,9-triazaspiro[4.5]dec-8-en-10-yl]-4-fluorophenyl]-1-(5-fluoro-2-pyridinyl)ethanone;2-[3-[(5S,10R)-8-amino-7,10-dimethyl-6,6-dioxo-2-(3H-pyrrol-5-ylmethyl)-6λ6-thia-2,7,9-triazaspiro[4.5]dec-8-en-10-yl]-4-fluorophenyl]-1-(5-fluoro-2-pyridinyl)ethanone;2-[3-[(5S,10R)-8-amino-7,10-dimethyl-2-(1,3-oxazol-5-ylmethyl)-6,6-dioxo-6λ6-thia-2,7,9-triazaspiro[4.5]dec-8-en-10-yl]-4-fluorophenyl]-1-(5-fluoro-2-pyridinyl)ethanone;2-[3-[(5R,10R)-8-amino-2-ethyl-7,10-dimethyl-6,6-dioxo-6λ6-thia-2,7,9-triazaspiro[4.5]dec-8-en-10-yl]-4-fluorophenyl]-1-(5-methoxy-2-pyridinyl)ethanone;2-[3-[(5R,10R)-8-amino-2-ethylsulfonyl-7,10-dimethyl-6,6-dioxo-6λ6-thia-2,7,9-triazaspiro[4.5]dec-8-en-10-yl]-4-fluorophenyl]-1-(5-methoxy-2-pyridinyl)ethanone?
The canonical SMILES for 2-[3-[(5S,10R)-8-amino-2-(cyclopropylmethyl)-7,10-dimethyl-6,6-dioxo-6λ6-thia-2,7,9-triazaspiro[4.5]dec-8-en-10-yl]-4-fluorophenyl]-1-(5-fluoro-2-pyridinyl)ethanone;2-[3-[(5S,10R)-8-amino-2-(3,3-difluorobutyl)-7,10-dimethyl-6,6-dioxo-6λ6-thia-2,7,9-triazaspiro[4.5]dec-8-en-10-yl]-4-fluorophenyl]-1-(5-fluoro-2-pyridinyl)ethanone;2-[3-[(5S,10R)-8-amino-7,10-dimethyl-6,6-dioxo-2-(3H-pyrrol-5-ylmethyl)-6λ6-thia-2,7,9-triazaspiro[4.5]dec-8-en-10-yl]-4-fluorophenyl]-1-(5-fluoro-2-pyridinyl)ethanone;2-[3-[(5S,10R)-8-amino-7,10-dimethyl-2-(1,3-oxazol-5-ylmethyl)-6,6-dioxo-6λ6-thia-2,7,9-triazaspiro[4.5]dec-8-en-10-yl]-4-fluorophenyl]-1-(5-fluoro-2-pyridinyl)ethanone;2-[3-[(5R,10R)-8-amino-2-ethyl-7,10-dimethyl-6,6-dioxo-6λ6-thia-2,7,9-triazaspiro[4.5]dec-8-en-10-yl]-4-fluorophenyl]-1-(5-methoxy-2-pyridinyl)ethanone;2-[3-[(5R,10R)-8-amino-2-ethylsulfonyl-7,10-dimethyl-6,6-dioxo-6λ6-thia-2,7,9-triazaspiro[4.5]dec-8-en-10-yl]-4-fluorophenyl]-1-(5-methoxy-2-pyridinyl)ethanone is CCN1CC[C@@]2(C1)[C@@](C)(c1cc(CC(=O)c3ccc(OC)cn3)ccc1F)N=C(N)N(C)S2(=O)=O.CCS(=O)(=O)N1CC[C@@]2(C1)[C@@](C)(c1cc(CC(=O)c3ccc(OC)cn3)ccc1F)N=C(N)N(C)S2(=O)=O.CN1C(N)=N[C@](C)(c2cc(CC(=O)c3ccc(F)cn3)ccc2F)[C@@]2(CCN(CC3=CCC=N3)C2)S1(=O)=O.CN1C(N)=N[C@](C)(c2cc(CC(=O)c3ccc(F)cn3)ccc2F)[C@@]2(CCN(CC3CC3)C2)S1(=O)=O.CN1C(N)=N[C@](C)(c2cc(CC(=O)c3ccc(F)cn3)ccc2F)[C@@]2(CCN(CCC(C)(F)F)C2)S1(=O)=O.CN1C(N)=N[C@](C)(c2cc(CC(=O)c3ccc(F)cn3)ccc2F)[C@@]2(CCN(Cc3cnco3)C2)S1(=O)=O.
What is the InChIKey of 2-[3-[(5S,10R)-8-amino-2-(cyclopropylmethyl)-7,10-dimethyl-6,6-dioxo-6λ6-thia-2,7,9-triazaspiro[4.5]dec-8-en-10-yl]-4-fluorophenyl]-1-(5-fluoro-2-pyridinyl)ethanone;2-[3-[(5S,10R)-8-amino-2-(3,3-difluorobutyl)-7,10-dimethyl-6,6-dioxo-6λ6-thia-2,7,9-triazaspiro[4.5]dec-8-en-10-yl]-4-fluorophenyl]-1-(5-fluoro-2-pyridinyl)ethanone;2-[3-[(5S,10R)-8-amino-7,10-dimethyl-6,6-dioxo-2-(3H-pyrrol-5-ylmethyl)-6λ6-thia-2,7,9-triazaspiro[4.5]dec-8-en-10-yl]-4-fluorophenyl]-1-(5-fluoro-2-pyridinyl)ethanone;2-[3-[(5S,10R)-8-amino-7,10-dimethyl-2-(1,3-oxazol-5-ylmethyl)-6,6-dioxo-6λ6-thia-2,7,9-triazaspiro[4.5]dec-8-en-10-yl]-4-fluorophenyl]-1-(5-fluoro-2-pyridinyl)ethanone;2-[3-[(5R,10R)-8-amino-2-ethyl-7,10-dimethyl-6,6-dioxo-6λ6-thia-2,7,9-triazaspiro[4.5]dec-8-en-10-yl]-4-fluorophenyl]-1-(5-methoxy-2-pyridinyl)ethanone;2-[3-[(5R,10R)-8-amino-2-ethylsulfonyl-7,10-dimethyl-6,6-dioxo-6λ6-thia-2,7,9-triazaspiro[4.5]dec-8-en-10-yl]-4-fluorophenyl]-1-(5-methoxy-2-pyridinyl)ethanone?
The InChIKey is MHMMHJZIVBLKII-LYAWNDLTSA-N. The full InChI is InChI=1S/C26H28F2N6O3S.C25H29F4N5O3S.C25H26F2N6O4S.C25H29F2N5O3S.C24H30FN5O6S2.C24H30FN5O4S/c1-25(20-12-17(5-7-21(20)28)13-23(35)22-8-6-18(27)14-31-22)26(38(36,37)33(2)24(29)32-25)9-11-34(16-26)15-19-4-3-10-30-19;1-23(28,29)8-10-34-11-9-25(15-34)24(2,32-22(30)33(3)38(25,36)37)18-12-16(4-6-19(18)27)13-21(35)20-7-5-17(26)14-31-20;1-24(19-9-16(3-5-20(19)27)10-22(34)21-6-4-17(26)11-30-21)25(38(35,36)32(2)23(28)31-24)7-8-33(14-25)13-18-12-29-15-37-18;1-24(19-11-17(5-7-20(19)27)12-22(33)21-8-6-18(26)13-29-21)25(36(34,35)31(2)23(28)30-24)9-10-32(15-25)14-16-3-4-16;1-5-37(32,33)30-11-10-24(15-30)23(2,28-22(26)29(3)38(24,34)35)18-12-16(6-8-19(18)25)13-21(31)20-9-7-17(36-4)14-27-20;1-5-30-11-10-24(15-30)23(2,28-22(26)29(3)35(24,32)33)18-12-16(6-8-19(18)25)13-21(31)20-9-7-17(34-4)14-27-20/h4-8,10,12,14H,3,9,11,13,15-16H2,1-2H3,(H2,29,32);4-7,12,14H,8-11,13,15H2,1-3H3,(H2,30,32);3-6,9,11-12,15H,7-8,10,13-14H2,1-2H3,(H2,28,31);5-8,11,13,16H,3-4,9-10,12,14-15H2,1-2H3,(H2,28,30);6-9,12,14H,5,10-11,13,15H2,1-4H3,(H2,26,28);6-9,12,14H,5,10-11,13,15H2,1-4H3,(H2,26,28)/t25-,26+;3*24-,25+;2*23-,24-/m111111/s1.
What are the key properties of 2-[3-[(5S,10R)-8-amino-2-(cyclopropylmethyl)-7,10-dimethyl-6,6-dioxo-6λ6-thia-2,7,9-triazaspiro[4.5]dec-8-en-10-yl]-4-fluorophenyl]-1-(5-fluoro-2-pyridinyl)ethanone;2-[3-[(5S,10R)-8-amino-2-(3,3-difluorobutyl)-7,10-dimethyl-6,6-dioxo-6λ6-thia-2,7,9-triazaspiro[4.5]dec-8-en-10-yl]-4-fluorophenyl]-1-(5-fluoro-2-pyridinyl)ethanone;2-[3-[(5S,10R)-8-amino-7,10-dimethyl-6,6-dioxo-2-(3H-pyrrol-5-ylmethyl)-6λ6-thia-2,7,9-triazaspiro[4.5]dec-8-en-10-yl]-4-fluorophenyl]-1-(5-fluoro-2-pyridinyl)ethanone;2-[3-[(5S,10R)-8-amino-7,10-dimethyl-2-(1,3-oxazol-5-ylmethyl)-6,6-dioxo-6λ6-thia-2,7,9-triazaspiro[4.5]dec-8-en-10-yl]-4-fluorophenyl]-1-(5-fluoro-2-pyridinyl)ethanone;2-[3-[(5R,10R)-8-amino-2-ethyl-7,10-dimethyl-6,6-dioxo-6λ6-thia-2,7,9-triazaspiro[4.5]dec-8-en-10-yl]-4-fluorophenyl]-1-(5-methoxy-2-pyridinyl)ethanone;2-[3-[(5R,10R)-8-amino-2-ethylsulfonyl-7,10-dimethyl-6,6-dioxo-6λ6-thia-2,7,9-triazaspiro[4.5]dec-8-en-10-yl]-4-fluorophenyl]-1-(5-methoxy-2-pyridinyl)ethanone?
2-[3-[(5S,10R)-8-amino-2-(cyclopropylmethyl)-7,10-dimethyl-6,6-dioxo-6λ6-thia-2,7,9-triazaspiro[4.5]dec-8-en-10-yl]-4-fluorophenyl]-1-(5-fluoro-2-pyridinyl)ethanone;2-[3-[(5S,10R)-8-amino-2-(3,3-difluorobutyl)-7,10-dimethyl-6,6-dioxo-6λ6-thia-2,7,9-triazaspiro[4.5]dec-8-en-10-yl]-4-fluorophenyl]-1-(5-fluoro-2-pyridinyl)ethanone;2-[3-[(5S,10R)-8-amino-7,10-dimethyl-6,6-dioxo-2-(3H-pyrrol-5-ylmethyl)-6λ6-thia-2,7,9-triazaspiro[4.5]dec-8-en-10-yl]-4-fluorophenyl]-1-(5-fluoro-2-pyridinyl)ethanone;2-[3-[(5S,10R)-8-amino-7,10-dimethyl-2-(1,3-oxazol-5-ylmethyl)-6,6-dioxo-6λ6-thia-2,7,9-triazaspiro[4.5]dec-8-en-10-yl]-4-fluorophenyl]-1-(5-fluoro-2-pyridinyl)ethanone;2-[3-[(5R,10R)-8-amino-2-ethyl-7,10-dimethyl-6,6-dioxo-6λ6-thia-2,7,9-triazaspiro[4.5]dec-8-en-10-yl]-4-fluorophenyl]-1-(5-methoxy-2-pyridinyl)ethanone;2-[3-[(5R,10R)-8-amino-2-ethylsulfonyl-7,10-dimethyl-6,6-dioxo-6λ6-thia-2,7,9-triazaspiro[4.5]dec-8-en-10-yl]-4-fluorophenyl]-1-(5-methoxy-2-pyridinyl)ethanone has a molecular weight of 3231.66 g/mol, XLogP of 13.32, 38 rotatable bonds, 6 hydrogen bond donors, and 48 hydrogen bond acceptors.
Where does this data come from?
All data for 2-[3-[(5S,10R)-8-amino-2-(cyclopropylmethyl)-7,10-dimethyl-6,6-dioxo-6λ6-thia-2,7,9-triazaspiro[4.5]dec-8-en-10-yl]-4-fluorophenyl]-1-(5-fluoro-2-pyridinyl)ethanone;2-[3-[(5S,10R)-8-amino-2-(3,3-difluorobutyl)-7,10-dimethyl-6,6-dioxo-6λ6-thia-2,7,9-triazaspiro[4.5]dec-8-en-10-yl]-4-fluorophenyl]-1-(5-fluoro-2-pyridinyl)ethanone;2-[3-[(5S,10R)-8-amino-7,10-dimethyl-6,6-dioxo-2-(3H-pyrrol-5-ylmethyl)-6λ6-thia-2,7,9-triazaspiro[4.5]dec-8-en-10-yl]-4-fluorophenyl]-1-(5-fluoro-2-pyridinyl)ethanone;2-[3-[(5S,10R)-8-amino-7,10-dimethyl-2-(1,3-oxazol-5-ylmethyl)-6,6-dioxo-6λ6-thia-2,7,9-triazaspiro[4.5]dec-8-en-10-yl]-4-fluorophenyl]-1-(5-fluoro-2-pyridinyl)ethanone;2-[3-[(5R,10R)-8-amino-2-ethyl-7,10-dimethyl-6,6-dioxo-6λ6-thia-2,7,9-triazaspiro[4.5]dec-8-en-10-yl]-4-fluorophenyl]-1-(5-methoxy-2-pyridinyl)ethanone;2-[3-[(5R,10R)-8-amino-2-ethylsulfonyl-7,10-dimethyl-6,6-dioxo-6λ6-thia-2,7,9-triazaspiro[4.5]dec-8-en-10-yl]-4-fluorophenyl]-1-(5-methoxy-2-pyridinyl)ethanone is sourced from PubChem (CID 159568376), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).