(3R)-2',3'-dimethyl-8-pyrimidin-5-ylspiro[2,4-dihydro-1H-naphthalene-3,5'-4H-imidazole];(3S)-2',3'-dimethyl-8-pyrimidin-5-ylspiro[2,4-dihydro-1H-naphthalene-3,5'-4H-imidazole];(3S)-8-(furan-2-yl)-3'-methylspiro[2,4-dihydro-1H-naphthalene-3,5'-4H-imidazole]-2'-amine;(5S)-8'-(furan-2-yl)spiro[1,4-dihydroimidazole-5,3'-2,4-dihydro-1H-naphthalene]-2-amine;(3R)-8-(furan-2-yl)spiro[2,4-dihydro-1H-naphthalene-3,2'-3,4-dihydropyrrole];(3R)-3'-methyl-8-pyrimidin-5-ylspiro[2,4-dihydro-1H-naphthalene-3,5'-4H-imidazole]-2'-amine;(3S)-3'-methyl-8-pyrimidin-5-ylspiro[2,4-dihydro-1H-naphthalene-3,5'-4H-imidazole]-2'-amine;(3S)-3'-methyl-8-thiophen-3-ylspiro[2,4-dihydro-1H-naphthalene-3,5'-4H-imidazole]-2'-amine;(5S)-8'-phenylspiro[1,4-dihydroimidazole-5,3'-2,4-dihydro-1H-naphthalene]-2-amine;(5S)-8'-thiophen-3-ylspiro[1,4-dihydroimidazole-5,3'-2,4-dihydro-1H-naphthalene]-2-amine

C171H186N34O3S2 — CID 159570783

IUPAC(3R)-2',3'-dimethyl-8-pyrimidin-5-ylspiro[2,4-dihydro-1H-naphthalene-3,5'-4H-imidazole];(3S)-2',3'-dimethyl-8-pyrimidin-5-ylspiro[2,4-dihydro-1H-naphthalene-3,5'-4H-imidazole];(3S)-8-(furan-2-yl)-3'-methylspiro[2,4-dihydro-1H-naphthalene-3,5'-4H-imidazole]-2'-amine;(5S)-8'-(furan-2-yl)spiro[1,4-dihydroimidazole-5,3'-2,4-dihydro-1H-naphthalene]-2-amine;(3R)-8-(furan-2-yl)spiro[2,4-dihydro-1H-naphthalene-3,2'-3,4-dihydropyrrole];(3R)-3'-methyl-8-pyrimidin-5-ylspiro[2,4-dihydro-1H-naphthalene-3,5'-4H-imidazole]-2'-amine;(3S)-3'-methyl-8-pyrimidin-5-ylspiro[2,4-dihydro-1H-naphthalene-3,5'-4H-imidazole]-2'-amine;(3S)-3'-methyl-8-thiophen-3-ylspiro[2,4-dihydro-1H-naphthalene-3,5'-4H-imidazole]-2'-amine;(5S)-8'-phenylspiro[1,4-dihydroimidazole-5,3'-2,4-dihydro-1H-naphthalene]-2-amine;(5S)-8'-thiophen-3-ylspiro[1,4-dihydroimidazole-5,3'-2,4-dihydro-1H-naphthalene]-2-amine
SMILESC1=N[C@@]2(CC1)CCc1c(cccc1-c1ccco1)C2.CC1=N[C@@]2(CCc3c(cccc3-c3cncnc3)C2)CN1C.CC1=N[C@]2(CCc3c(cccc3-c3cncnc3)C2)CN1C.CN1C[C@@]2(CCc3c(cccc3-c3ccco3)C2)N=C1N.CN1C[C@@]2(CCc3c(cccc3-c3ccsc3)C2)N=C1N.CN1C[C@@]2(CCc3c(cccc3-c3cncnc3)C2)N=C1N.CN1C[C@]2(CCc3c(cccc3-c3cncnc3)C2)N=C1N.NC1=NC[C@@]2(CCc3c(cccc3-c3ccccc3)C2)N1.NC1=NC[C@@]2(CCc3c(cccc3-c3ccco3)C2)N1.NC1=NC[C@@]2(CCc3c(cccc3-c3ccsc3)C2)N1
InChIInChI=1S/2C18H20N4.C18H19N3.2C17H19N5.C17H19N3O.C17H19N3S.C17H17NO.C16H17N3O.C16H17N3S/c2*1-13-21-18(11-22(13)2)7-6-17-14(8-18)4-3-5-16(17)15-9-19-12-20-10-15;19-17-20-12-18(21-17)10-9-16-14(11-18)7-4-8-15(16)13-5-2-1-3-6-13;2*1-22-10-17(21-16(22)18)6-5-15-12(7-17)3-2-4-14(15)13-8-19-11-20-9-13;1-20-11-17(19-16(20)18)8-7-13-12(10-17)4-2-5-14(13)15-6-3-9-21-15;1-20-11-17(19-16(20)18)7-5-15-12(9-17)3-2-4-14(15)13-6-8-21-10-13;1-4-13-12-17(8-3-10-18-17)9-7-14(13)15(5-1)16-6-2-11-19-16;17-15-18-10-16(19-15)7-6-12-11(9-16)3-1-4-13(12)14-5-2-8-20-14;17-15-18-10-16(19-15)6-4-14-11(8-16)2-1-3-13(14)12-5-7-20-9-12/h2*3-5,9-10,12H,6-8,11H2,1-2H3;1-8H,9-12H2,(H3,19,20,21);2*2-4,8-9,11H,5-7,10H2,1H3,(H2,18,21);2-6,9H,7-8,10-11H2,1H3,(H2,18,19);2-4,6,8,10H,5,7,9,11H2,1H3,(H2,18,19);1-2,4-6,10-11H,3,7-9,12H2;1-5,8H,6-7,9-10H2,(H3,17,18,19);1-3,5,7,9H,4,6,8,10H2,(H3,17,18,19)/t3*18-;5*17-;2*16-/m1001000000/s1
InChIKeyMHUAXIPGALJAFG-XSNAKOEFSA-N
MW2829.74 g/mol
LogP25.26
Rot. Bonds10

About (3R)-2',3'-dimethyl-8-pyrimidin-5-ylspiro[2,4-dihydro-1H-naphthalene-3,5'-4H-imidazole];(3S)-2',3'-dimethyl-8-pyrimidin-5-ylspiro[2,4-dihydro-1H-naphthalene-3,5'-4H-imidazole];(3S)-8-(furan-2-yl)-3'-methylspiro[2,4-dihydro-1H-naphthalene-3,5'-4H-imidazole]-2'-amine;(5S)-8'-(furan-2-yl)spiro[1,4-dihydroimidazole-5,3'-2,4-dihydro-1H-naphthalene]-2-amine;(3R)-8-(furan-2-yl)spiro[2,4-dihydro-1H-naphthalene-3,2'-3,4-dihydropyrrole];(3R)-3'-methyl-8-pyrimidin-5-ylspiro[2,4-dihydro-1H-naphthalene-3,5'-4H-imidazole]-2'-amine;(3S)-3'-methyl-8-pyrimidin-5-ylspiro[2,4-dihydro-1H-naphthalene-3,5'-4H-imidazole]-2'-amine;(3S)-3'-methyl-8-thiophen-3-ylspiro[2,4-dihydro-1H-naphthalene-3,5'-4H-imidazole]-2'-amine;(5S)-8'-phenylspiro[1,4-dihydroimidazole-5,3'-2,4-dihydro-1H-naphthalene]-2-amine;(5S)-8'-thiophen-3-ylspiro[1,4-dihydroimidazole-5,3'-2,4-dihydro-1H-naphthalene]-2-amine

(3R)-2',3'-dimethyl-8-pyrimidin-5-ylspiro[2,4-dihydro-1H-naphthalene-3,5'-4H-imidazole];(3S)-2',3'-dimethyl-8-pyrimidin-5-ylspiro[2,4-dihydro-1H-naphthalene-3,5'-4H-imidazole];(3S)-8-(furan-2-yl)-3'-methylspiro[2,4-dihydro-1H-naphthalene-3,5'-4H-imidazole]-2'-amine;(5S)-8'-(furan-2-yl)spiro[1,4-dihydroimidazole-5,3'-2,4-dihydro-1H-naphthalene]-2-amine;(3R)-8-(furan-2-yl)spiro[2,4-dihydro-1H-naphthalene-3,2'-3,4-dihydropyrrole];(3R)-3'-methyl-8-pyrimidin-5-ylspiro[2,4-dihydro-1H-naphthalene-3,5'-4H-imidazole]-2'-amine;(3S)-3'-methyl-8-pyrimidin-5-ylspiro[2,4-dihydro-1H-naphthalene-3,5'-4H-imidazole]-2'-amine;(3S)-3'-methyl-8-thiophen-3-ylspiro[2,4-dihydro-1H-naphthalene-3,5'-4H-imidazole]-2'-amine;(5S)-8'-phenylspiro[1,4-dihydroimidazole-5,3'-2,4-dihydro-1H-naphthalene]-2-amine;(5S)-8'-thiophen-3-ylspiro[1,4-dihydroimidazole-5,3'-2,4-dihydro-1H-naphthalene]-2-amine (PubChem CID 159570783) has the molecular formula C171H186N34O3S2 and a molecular weight of 2829.74 g/mol. Its IUPAC name is (3R)-2',3'-dimethyl-8-pyrimidin-5-ylspiro[2,4-dihydro-1H-naphthalene-3,5'-4H-imidazole];(3S)-2',3'-dimethyl-8-pyrimidin-5-ylspiro[2,4-dihydro-1H-naphthalene-3,5'-4H-imidazole];(3S)-8-(furan-2-yl)-3'-methylspiro[2,4-dihydro-1H-naphthalene-3,5'-4H-imidazole]-2'-amine;(5S)-8'-(furan-2-yl)spiro[1,4-dihydroimidazole-5,3'-2,4-dihydro-1H-naphthalene]-2-amine;(3R)-8-(furan-2-yl)spiro[2,4-dihydro-1H-naphthalene-3,2'-3,4-dihydropyrrole];(3R)-3'-methyl-8-pyrimidin-5-ylspiro[2,4-dihydro-1H-naphthalene-3,5'-4H-imidazole]-2'-amine;(3S)-3'-methyl-8-pyrimidin-5-ylspiro[2,4-dihydro-1H-naphthalene-3,5'-4H-imidazole]-2'-amine;(3S)-3'-methyl-8-thiophen-3-ylspiro[2,4-dihydro-1H-naphthalene-3,5'-4H-imidazole]-2'-amine;(5S)-8'-phenylspiro[1,4-dihydroimidazole-5,3'-2,4-dihydro-1H-naphthalene]-2-amine;(5S)-8'-thiophen-3-ylspiro[1,4-dihydroimidazole-5,3'-2,4-dihydro-1H-naphthalene]-2-amine.

Molecular Properties

Compound Name(3R)-2',3'-dimethyl-8-pyrimidin-5-ylspiro[2,4-dihydro-1H-naphthalene-3,5'-4H-imidazole];(3S)-2',3'-dimethyl-8-pyrimidin-5-ylspiro[2,4-dihydro-1H-naphthalene-3,5'-4H-imidazole];(3S)-8-(furan-2-yl)-3'-methylspiro[2,4-dihydro-1H-naphthalene-3,5'-4H-imidazole]-2'-amine;(5S)-8'-(furan-2-yl)spiro[1,4-dihydroimidazole-5,3'-2,4-dihydro-1H-naphthalene]-2-amine;(3R)-8-(furan-2-yl)spiro[2,4-dihydro-1H-naphthalene-3,2'-3,4-dihydropyrrole];(3R)-3'-methyl-8-pyrimidin-5-ylspiro[2,4-dihydro-1H-naphthalene-3,5'-4H-imidazole]-2'-amine;(3S)-3'-methyl-8-pyrimidin-5-ylspiro[2,4-dihydro-1H-naphthalene-3,5'-4H-imidazole]-2'-amine;(3S)-3'-methyl-8-thiophen-3-ylspiro[2,4-dihydro-1H-naphthalene-3,5'-4H-imidazole]-2'-amine;(5S)-8'-phenylspiro[1,4-dihydroimidazole-5,3'-2,4-dihydro-1H-naphthalene]-2-amine;(5S)-8'-thiophen-3-ylspiro[1,4-dihydroimidazole-5,3'-2,4-dihydro-1H-naphthalene]-2-amine
PubChem CID159570783
Molecular FormulaC171H186N34O3S2
Molecular Weight2829.74 g/mol
Exact Mass2827.49
IUPAC Name(3R)-2',3'-dimethyl-8-pyrimidin-5-ylspiro[2,4-dihydro-1H-naphthalene-3,5'-4H-imidazole];(3S)-2',3'-dimethyl-8-pyrimidin-5-ylspiro[2,4-dihydro-1H-naphthalene-3,5'-4H-imidazole];(3S)-8-(furan-2-yl)-3'-methylspiro[2,4-dihydro-1H-naphthalene-3,5'-4H-imidazole]-2'-amine;(5S)-8'-(furan-2-yl)spiro[1,4-dihydroimidazole-5,3'-2,4-dihydro-1H-naphthalene]-2-amine;(3R)-8-(furan-2-yl)spiro[2,4-dihydro-1H-naphthalene-3,2'-3,4-dihydropyrrole];(3R)-3'-methyl-8-pyrimidin-5-ylspiro[2,4-dihydro-1H-naphthalene-3,5'-4H-imidazole]-2'-amine;(3S)-3'-methyl-8-pyrimidin-5-ylspiro[2,4-dihydro-1H-naphthalene-3,5'-4H-imidazole]-2'-amine;(3S)-3'-methyl-8-thiophen-3-ylspiro[2,4-dihydro-1H-naphthalene-3,5'-4H-imidazole]-2'-amine;(5S)-8'-phenylspiro[1,4-dihydroimidazole-5,3'-2,4-dihydro-1H-naphthalene]-2-amine;(5S)-8'-thiophen-3-ylspiro[1,4-dihydroimidazole-5,3'-2,4-dihydro-1H-naphthalene]-2-amine
SMILESC1=N[C@@]2(CC1)CCc1c(cccc1-c1ccco1)C2.CC1=N[C@@]2(CCc3c(cccc3-c3cncnc3)C2)CN1C.CC1=N[C@]2(CCc3c(cccc3-c3cncnc3)C2)CN1C.CN1C[C@@]2(CCc3c(cccc3-c3ccco3)C2)N=C1N.CN1C[C@@]2(CCc3c(cccc3-c3ccsc3)C2)N=C1N.CN1C[C@@]2(CCc3c(cccc3-c3cncnc3)C2)N=C1N.CN1C[C@]2(CCc3c(cccc3-c3cncnc3)C2)N=C1N.NC1=NC[C@@]2(CCc3c(cccc3-c3ccccc3)C2)N1.NC1=NC[C@@]2(CCc3c(cccc3-c3ccco3)C2)N1.NC1=NC[C@@]2(CCc3c(cccc3-c3ccsc3)C2)N1
InChIInChI=1S/2C18H20N4.C18H19N3.2C17H19N5.C17H19N3O.C17H19N3S.C17H17NO.C16H17N3O.C16H17N3S/c2*1-13-21-18(11-22(13)2)7-6-17-14(8-18)4-3-5-16(17)15-9-19-12-20-10-15;19-17-20-12-18(21-17)10-9-16-14(11-18)7-4-8-15(16)13-5-2-1-3-6-13;2*1-22-10-17(21-16(22)18)6-5-15-12(7-17)3-2-4-14(15)13-8-19-11-20-9-13;1-20-11-17(19-16(20)18)8-7-13-12(10-17)4-2-5-14(13)15-6-3-9-21-15;1-20-11-17(19-16(20)18)7-5-15-12(9-17)3-2-4-14(15)13-6-8-21-10-13;1-4-13-12-17(8-3-10-18-17)9-7-14(13)15(5-1)16-6-2-11-19-16;17-15-18-10-16(19-15)7-6-12-11(9-16)3-1-4-13(12)14-5-2-8-20-14;17-15-18-10-16(19-15)6-4-14-11(8-16)2-1-3-13(14)12-5-7-20-9-12/h2*3-5,9-10,12H,6-8,11H2,1-2H3;1-8H,9-12H2,(H3,19,20,21);2*2-4,8-9,11H,5-7,10H2,1H3,(H2,18,21);2-6,9H,7-8,10-11H2,1H3,(H2,18,19);2-4,6,8,10H,5,7,9,11H2,1H3,(H2,18,19);1-2,4-6,10-11H,3,7-9,12H2;1-5,8H,6-7,9-10H2,(H3,17,18,19);1-3,5,7,9H,4,6,8,10H2,(H3,17,18,19)/t3*18-;5*17-;2*16-/m1001000000/s1
InChIKeyMHUAXIPGALJAFG-XSNAKOEFSA-N
XLogP25.26
TPSA503.81 Ų
H-Bond Donors10
H-Bond Acceptors39
Rotatable Bonds10
Heavy Atoms210
Complexity—

Lipinski Rule of Five

4 violations

RuleValue
MW ≤ 5002829.74
LogP ≤ 525.26
H-Bond Donors ≤ 510
H-Bond Acceptors ≤ 1039

Analyze (3R)-2',3'-dimethyl-8-pyrimidin-5-ylspiro[2,4-dihydro-1H-naphthalene-3,5'-4H-imidazole];(3S)-2',3'-dimethyl-8-pyrimidin-5-ylspiro[2,4-dihydro-1H-naphthalene-3,5'-4H-imidazole];(3S)-8-(furan-2-yl)-3'-methylspiro[2,4-dihydro-1H-naphthalene-3,5'-4H-imidazole]-2'-amine;(5S)-8'-(furan-2-yl)spiro[1,4-dihydroimidazole-5,3'-2,4-dihydro-1H-naphthalene]-2-amine;(3R)-8-(furan-2-yl)spiro[2,4-dihydro-1H-naphthalene-3,2'-3,4-dihydropyrrole];(3R)-3'-methyl-8-pyrimidin-5-ylspiro[2,4-dihydro-1H-naphthalene-3,5'-4H-imidazole]-2'-amine;(3S)-3'-methyl-8-pyrimidin-5-ylspiro[2,4-dihydro-1H-naphthalene-3,5'-4H-imidazole]-2'-amine;(3S)-3'-methyl-8-thiophen-3-ylspiro[2,4-dihydro-1H-naphthalene-3,5'-4H-imidazole]-2'-amine;(5S)-8'-phenylspiro[1,4-dihydroimidazole-5,3'-2,4-dihydro-1H-naphthalene]-2-amine;(5S)-8'-thiophen-3-ylspiro[1,4-dihydroimidazole-5,3'-2,4-dihydro-1H-naphthalene]-2-amine with MolForge

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Related Compounds

(5Z)-5-[[2-[[4-[[4-fluoro-2-(furan-2-yl)phenyl]methylamino]cyclohexyl]methyl]pyrimidin-4-yl]methylidene]thiolane-2,4-dione;(5Z)-5-[[2-[[4-[1-(6-thiophen-3-yl-2-pyridinyl)ethylamino]cyclohexyl]methyl]pyrimidin-4-yl]methylidene]thiolane-2,4-dione;(5Z)-5-[[2-[[4-[(6-thiophen-2-yl-2-pyridinyl)methylamino]cyclohexyl]methyl]pyrimidin-4-yl]methylidene]thiolane-2,4-dione;(5Z)-5-[[2-[[4-[[6-[2-(trifluoromethyl)phenyl]-2-pyridinyl]methylamino]cyclohexyl]methyl]pyrimidin-4-yl]methylidene]thiolane-2,4-dione
CID 157512391
(5Z)-5-[[2-[[4-[[4-fluoro-2-(furan-2-yl)phenyl]methylamino]cyclohexyl]methyl]pyrimidin-4-yl]methylidene]thiolane-2,4-dione;(5Z)-5-[[2-[[4-[(6-fluoronaphthalen-2-yl)methylamino]cyclohexyl]methyl]pyrimidin-4-yl]methylidene]thiolane-2,4-dione;(5Z)-5-[[2-[[4-[[3-(furan-2-yl)phenyl]methylamino]cyclohexyl]methyl]pyrimidin-4-yl]methylidene]thiolane-2,4-dione;bis((5Z)-5-[[2-[[4-(2-phenylethylamino)cyclohexyl]methyl]pyrimidin-4-yl]methylidene]thiolane-2,4-dione);bis((5Z)-5-[[2-[[4-(2-pyridin-2-ylethylamino)cyclohexyl]methyl]pyrimidin-4-yl]methylidene]thiolane-2,4-dione);(5Z)-5-[[2-[[4-[1-(6-thiophen-3-yl-2-pyridinyl)ethylamino]cyclohexyl]methyl]pyrimidin-4-yl]methylidene]thiolane-2,4-dione;(5Z)-5-[[2-[[4-[[6-[2-(trifluoromethyl)phenyl]-2-pyridinyl]methylamino]cyclohexyl]methyl]pyrimidin-4-yl]methylidene]thiolane-2,4-dione
CID 159592312
CID 160790822
CID 160790822
3-[6-(4,4-difluoropiperidin-1-yl)pyrimidin-4-yl]-5-(furan-3-yl)-1H-isoindole;3-[6-(4,4-difluoropiperidin-1-yl)pyrimidin-4-yl]-5-(4-methoxy-3-pyridinyl)-1H-isoindole;3-[6-(4,4-difluoropiperidin-1-yl)pyrimidin-4-yl]-5-pyridin-3-yl-1H-isoindole;3-[6-(4,4-difluoropiperidin-1-yl)pyrimidin-4-yl]-5-(1,2,3,6-tetrahydropyridin-4-yl)-1H-isoindole;3-[6-(4,4-difluoropiperidin-1-yl)pyrimidin-4-yl]-5-thiophen-3-yl-1H-isoindole;3-[6-(4-methylsulfonylpiperazin-1-yl)pyrimidin-4-yl]-5-pyridin-3-yl-1H-isoindole
CID 161136576
2-phenyl-5-propan-2-ylpyrazine;2-phenyl-3-propan-2-ylpyridine;5-phenyl-2-propan-2-ylpyridine;3-phenyl-2-propan-2-yl-1H-pyrrole;2-phenyl-5-propan-2-yl-1,3-thiazole;2-phenyl-4-propan-2-ylthiophene;2-(4-propan-2-ylphenyl)furan;2-(4-propan-2-ylphenyl)pyridine;4-(3-propan-2-ylphenyl)pyridine;5-(4-propan-2-ylphenyl)pyrimidine;3-(4-propan-2-ylphenyl)-1H-pyrrole;2-(4-propan-2-ylphenyl)-1,3-thiazole
CID 157099887
(3S)-8-(furan-2-yl)-3'-methylspiro[2,4-dihydro-1H-naphthalene-3,5'-4H-imidazole];(5R)-2-methyl-8'-pyrimidin-5-ylspiro[1,4-dihydroimidazole-5,3'-2,4-dihydro-1H-naphthalene];(5S)-2-methyl-8'-pyrimidin-5-ylspiro[1,4-dihydroimidazole-5,3'-2,4-dihydro-1H-naphthalene];(3S)-8-pyrimidin-5-ylspiro[2,4-dihydro-1H-naphthalene-3,2'-3,4-dihydropyrrole];(3R)-8-pyrimidin-5-ylspiro[2,4-dihydro-1H-naphthalene-3,2'-3,4-dihydropyrrole];(3R)-8-thiophen-3-ylspiro[2,4-dihydro-1H-naphthalene-3,2'-3,4-dihydropyrrole]
CID 157102802
8-(furan-3-yl)spiro[2,4-dihydro-1H-naphthalene-3,2'-3,4-dihydropyrrole];bis(2-methyl-8'-pyrimidin-5-ylspiro[1,4-dihydroimidazole-5,3'-2,4-dihydro-1H-naphthalene]);(2R)-2'-methyl-4-pyrimidin-5-ylspiro[1,3-dihydroindene-2,4'-5H-1,3-oxazole];2'-methyl-4-pyrimidin-5-ylspiro[1,3-dihydroindene-2,4'-5H-1,3-oxazole];3'-methyl-8-pyrimidin-5-ylspiro[2,4-dihydro-1H-naphthalene-3,5'-4H-imidazole];(2S)-2'-methyl-5-pyrimidin-5-ylspiro[3,4-dihydro-1H-naphthalene-2,4'-5H-1,3-oxazole]-1-ol;1'-methyl-8-pyrimidin-5-ylspiro[2,4-dihydro-1H-naphthalene-3,2'-3H-pyrrole];8-phenylspiro[2,4-dihydro-1H-naphthalene-3,2'-3,4-dihydropyrrole];8'-pyrimidin-5-ylspiro[1,4-dihydroimidazole-5,3'-2,4-dihydro-1H-naphthalene];8-thiophen-2-ylspiro[2,4-dihydro-1H-naphthalene-3,2'-3,4-dihydropyrrole];8-thiophen-3-ylspiro[2,4-dihydro-1H-naphthalene-3,2'-3,4-dihydropyrrole]
CID 157225556
2-Dibenzofuran-4-yl-5-[6-(6-dibenzothiophen-4-yl-3-pyridinyl)naphthalen-2-yl]pyrimidine;2-dibenzofuran-4-yl-5-[6-(2-dibenzothiophen-4-ylpyrimidin-5-yl)naphthalen-2-yl]pyrimidine;5-[6-(6-dibenzofuran-4-yl-3-pyridinyl)naphthalen-2-yl]-2-dibenzothiophen-4-ylpyrimidine
CID 157369836
(5R)-8'-(furan-2-yl)-2-methylspiro[1,4-dihydroimidazole-5,3'-2,4-dihydro-1H-naphthalene];(3R)-2'-methyl-5-(4-methyl-3-pyridinyl)spiro[2,4-dihydro-1H-naphthalene-3,4'-5H-1,3-oxazole];(3S)-2'-methyl-5-(4-methyl-3-pyridinyl)spiro[2,4-dihydro-1H-naphthalene-3,4'-5H-1,3-oxazole];(3R)-2'-methyl-5-pyridin-3-ylspiro[2,4-dihydro-1H-naphthalene-3,4'-5H-1,3-oxazole];(3S)-5'-methyl-8-pyrimidin-5-ylspiro[2,4-dihydro-1H-naphthalene-3,2'-3,4-dihydropyrrole];(3S)-2'-methyl-5-pyrimidin-5-ylspiro[2,4-dihydro-1H-naphthalene-3,4'-5H-1,3-oxazole]
CID 157406931
8-(furan-3-yl)spiro[2,4-dihydro-1H-naphthalene-3,2'-3,4-dihydropyrrole];2-methyl-8'-pyrimidin-5-ylspiro[1,4-dihydroimidazole-5,3'-2,4-dihydro-1H-naphthalene];5'-methyl-8-pyrimidin-5-ylspiro[2,4-dihydro-1H-naphthalene-3,2'-3,4-dihydropyrrole];8-thiophen-2-ylspiro[2,4-dihydro-1H-naphthalene-3,2'-3,4-dihydropyrrole];8-thiophen-3-ylspiro[2,4-dihydro-1H-naphthalene-3,2'-3,4-dihydropyrrole]
CID 157437545
(5Z)-5-[[2-[[4-[3-[4-fluoro-2-(furan-2-yl)phenyl]propyl]cyclohexyl]methyl]pyrimidin-4-yl]methylidene]-1,3-thiazolidine-2,4-dione;(5Z)-5-[[2-[[4-[3-(6-fluoronaphthalen-2-yl)propyl]cyclohexyl]methyl]pyrimidin-4-yl]methylidene]-1,3-thiazolidine-2,4-dione;(5Z)-5-[[2-[[4-(3-naphthalen-1-ylpropyl)cyclohexyl]methyl]pyrimidin-4-yl]methylidene]-1,3-thiazolidine-2,4-dione;(5Z)-5-[[2-[[4-(4-phenylbutyl)cyclohexyl]methyl]pyrimidin-4-yl]methylidene]-1,3-thiazolidine-2,4-dione;(5Z)-5-[[2-[[4-(4-pyridin-2-ylbutyl)cyclohexyl]methyl]pyrimidin-4-yl]methylidene]-1,3-thiazolidine-2,4-dione;(5Z)-5-[[2-[[4-[3-(2-pyridin-3-ylphenyl)propyl]cyclohexyl]methyl]pyrimidin-4-yl]methylidene]-1,3-thiazolidine-2,4-dione;(5Z)-5-[[2-[[4-[3-(2-thiophen-3-yl-3-pyridinyl)propyl]cyclohexyl]methyl]pyrimidin-4-yl]methylidene]-1,3-thiazolidine-2,4-dione
CID 157457754
2-Methyl-5-(4-propan-2-ylphenyl)pyrimidine;tris(5-methyl-2-(4-propan-2-ylphenyl)pyrimidine);1-phenyl-4-propan-2-ylbenzene;3-(3-propan-2-ylphenyl)furan;2-(4-propan-2-ylphenyl)pyrazine;2-(4-propan-2-ylphenyl)pyridine;2-(4-propan-2-ylphenyl)pyrimidine;2-(4-propan-2-ylphenyl)-1,3-thiazole;2-(3-propan-2-ylphenyl)thiophene;3-(3-propan-2-ylphenyl)thiophene
CID 157462105

Frequently Asked Questions

What is the IUPAC name of (3R)-2',3'-dimethyl-8-pyrimidin-5-ylspiro[2,4-dihydro-1H-naphthalene-3,5'-4H-imidazole];(3S)-2',3'-dimethyl-8-pyrimidin-5-ylspiro[2,4-dihydro-1H-naphthalene-3,5'-4H-imidazole];(3S)-8-(furan-2-yl)-3'-methylspiro[2,4-dihydro-1H-naphthalene-3,5'-4H-imidazole]-2'-amine;(5S)-8'-(furan-2-yl)spiro[1,4-dihydroimidazole-5,3'-2,4-dihydro-1H-naphthalene]-2-amine;(3R)-8-(furan-2-yl)spiro[2,4-dihydro-1H-naphthalene-3,2'-3,4-dihydropyrrole];(3R)-3'-methyl-8-pyrimidin-5-ylspiro[2,4-dihydro-1H-naphthalene-3,5'-4H-imidazole]-2'-amine;(3S)-3'-methyl-8-pyrimidin-5-ylspiro[2,4-dihydro-1H-naphthalene-3,5'-4H-imidazole]-2'-amine;(3S)-3'-methyl-8-thiophen-3-ylspiro[2,4-dihydro-1H-naphthalene-3,5'-4H-imidazole]-2'-amine;(5S)-8'-phenylspiro[1,4-dihydroimidazole-5,3'-2,4-dihydro-1H-naphthalene]-2-amine;(5S)-8'-thiophen-3-ylspiro[1,4-dihydroimidazole-5,3'-2,4-dihydro-1H-naphthalene]-2-amine?
The IUPAC name of (3R)-2',3'-dimethyl-8-pyrimidin-5-ylspiro[2,4-dihydro-1H-naphthalene-3,5'-4H-imidazole];(3S)-2',3'-dimethyl-8-pyrimidin-5-ylspiro[2,4-dihydro-1H-naphthalene-3,5'-4H-imidazole];(3S)-8-(furan-2-yl)-3'-methylspiro[2,4-dihydro-1H-naphthalene-3,5'-4H-imidazole]-2'-amine;(5S)-8'-(furan-2-yl)spiro[1,4-dihydroimidazole-5,3'-2,4-dihydro-1H-naphthalene]-2-amine;(3R)-8-(furan-2-yl)spiro[2,4-dihydro-1H-naphthalene-3,2'-3,4-dihydropyrrole];(3R)-3'-methyl-8-pyrimidin-5-ylspiro[2,4-dihydro-1H-naphthalene-3,5'-4H-imidazole]-2'-amine;(3S)-3'-methyl-8-pyrimidin-5-ylspiro[2,4-dihydro-1H-naphthalene-3,5'-4H-imidazole]-2'-amine;(3S)-3'-methyl-8-thiophen-3-ylspiro[2,4-dihydro-1H-naphthalene-3,5'-4H-imidazole]-2'-amine;(5S)-8'-phenylspiro[1,4-dihydroimidazole-5,3'-2,4-dihydro-1H-naphthalene]-2-amine;(5S)-8'-thiophen-3-ylspiro[1,4-dihydroimidazole-5,3'-2,4-dihydro-1H-naphthalene]-2-amine (CID 159570783) is (3R)-2',3'-dimethyl-8-pyrimidin-5-ylspiro[2,4-dihydro-1H-naphthalene-3,5'-4H-imidazole];(3S)-2',3'-dimethyl-8-pyrimidin-5-ylspiro[2,4-dihydro-1H-naphthalene-3,5'-4H-imidazole];(3S)-8-(furan-2-yl)-3'-methylspiro[2,4-dihydro-1H-naphthalene-3,5'-4H-imidazole]-2'-amine;(5S)-8'-(furan-2-yl)spiro[1,4-dihydroimidazole-5,3'-2,4-dihydro-1H-naphthalene]-2-amine;(3R)-8-(furan-2-yl)spiro[2,4-dihydro-1H-naphthalene-3,2'-3,4-dihydropyrrole];(3R)-3'-methyl-8-pyrimidin-5-ylspiro[2,4-dihydro-1H-naphthalene-3,5'-4H-imidazole]-2'-amine;(3S)-3'-methyl-8-pyrimidin-5-ylspiro[2,4-dihydro-1H-naphthalene-3,5'-4H-imidazole]-2'-amine;(3S)-3'-methyl-8-thiophen-3-ylspiro[2,4-dihydro-1H-naphthalene-3,5'-4H-imidazole]-2'-amine;(5S)-8'-phenylspiro[1,4-dihydroimidazole-5,3'-2,4-dihydro-1H-naphthalene]-2-amine;(5S)-8'-thiophen-3-ylspiro[1,4-dihydroimidazole-5,3'-2,4-dihydro-1H-naphthalene]-2-amine.
What is the SMILES notation for (3R)-2',3'-dimethyl-8-pyrimidin-5-ylspiro[2,4-dihydro-1H-naphthalene-3,5'-4H-imidazole];(3S)-2',3'-dimethyl-8-pyrimidin-5-ylspiro[2,4-dihydro-1H-naphthalene-3,5'-4H-imidazole];(3S)-8-(furan-2-yl)-3'-methylspiro[2,4-dihydro-1H-naphthalene-3,5'-4H-imidazole]-2'-amine;(5S)-8'-(furan-2-yl)spiro[1,4-dihydroimidazole-5,3'-2,4-dihydro-1H-naphthalene]-2-amine;(3R)-8-(furan-2-yl)spiro[2,4-dihydro-1H-naphthalene-3,2'-3,4-dihydropyrrole];(3R)-3'-methyl-8-pyrimidin-5-ylspiro[2,4-dihydro-1H-naphthalene-3,5'-4H-imidazole]-2'-amine;(3S)-3'-methyl-8-pyrimidin-5-ylspiro[2,4-dihydro-1H-naphthalene-3,5'-4H-imidazole]-2'-amine;(3S)-3'-methyl-8-thiophen-3-ylspiro[2,4-dihydro-1H-naphthalene-3,5'-4H-imidazole]-2'-amine;(5S)-8'-phenylspiro[1,4-dihydroimidazole-5,3'-2,4-dihydro-1H-naphthalene]-2-amine;(5S)-8'-thiophen-3-ylspiro[1,4-dihydroimidazole-5,3'-2,4-dihydro-1H-naphthalene]-2-amine?
The canonical SMILES for (3R)-2',3'-dimethyl-8-pyrimidin-5-ylspiro[2,4-dihydro-1H-naphthalene-3,5'-4H-imidazole];(3S)-2',3'-dimethyl-8-pyrimidin-5-ylspiro[2,4-dihydro-1H-naphthalene-3,5'-4H-imidazole];(3S)-8-(furan-2-yl)-3'-methylspiro[2,4-dihydro-1H-naphthalene-3,5'-4H-imidazole]-2'-amine;(5S)-8'-(furan-2-yl)spiro[1,4-dihydroimidazole-5,3'-2,4-dihydro-1H-naphthalene]-2-amine;(3R)-8-(furan-2-yl)spiro[2,4-dihydro-1H-naphthalene-3,2'-3,4-dihydropyrrole];(3R)-3'-methyl-8-pyrimidin-5-ylspiro[2,4-dihydro-1H-naphthalene-3,5'-4H-imidazole]-2'-amine;(3S)-3'-methyl-8-pyrimidin-5-ylspiro[2,4-dihydro-1H-naphthalene-3,5'-4H-imidazole]-2'-amine;(3S)-3'-methyl-8-thiophen-3-ylspiro[2,4-dihydro-1H-naphthalene-3,5'-4H-imidazole]-2'-amine;(5S)-8'-phenylspiro[1,4-dihydroimidazole-5,3'-2,4-dihydro-1H-naphthalene]-2-amine;(5S)-8'-thiophen-3-ylspiro[1,4-dihydroimidazole-5,3'-2,4-dihydro-1H-naphthalene]-2-amine is C1=N[C@@]2(CC1)CCc1c(cccc1-c1ccco1)C2.CC1=N[C@@]2(CCc3c(cccc3-c3cncnc3)C2)CN1C.CC1=N[C@]2(CCc3c(cccc3-c3cncnc3)C2)CN1C.CN1C[C@@]2(CCc3c(cccc3-c3ccco3)C2)N=C1N.CN1C[C@@]2(CCc3c(cccc3-c3ccsc3)C2)N=C1N.CN1C[C@@]2(CCc3c(cccc3-c3cncnc3)C2)N=C1N.CN1C[C@]2(CCc3c(cccc3-c3cncnc3)C2)N=C1N.NC1=NC[C@@]2(CCc3c(cccc3-c3ccccc3)C2)N1.NC1=NC[C@@]2(CCc3c(cccc3-c3ccco3)C2)N1.NC1=NC[C@@]2(CCc3c(cccc3-c3ccsc3)C2)N1.
What is the InChIKey of (3R)-2',3'-dimethyl-8-pyrimidin-5-ylspiro[2,4-dihydro-1H-naphthalene-3,5'-4H-imidazole];(3S)-2',3'-dimethyl-8-pyrimidin-5-ylspiro[2,4-dihydro-1H-naphthalene-3,5'-4H-imidazole];(3S)-8-(furan-2-yl)-3'-methylspiro[2,4-dihydro-1H-naphthalene-3,5'-4H-imidazole]-2'-amine;(5S)-8'-(furan-2-yl)spiro[1,4-dihydroimidazole-5,3'-2,4-dihydro-1H-naphthalene]-2-amine;(3R)-8-(furan-2-yl)spiro[2,4-dihydro-1H-naphthalene-3,2'-3,4-dihydropyrrole];(3R)-3'-methyl-8-pyrimidin-5-ylspiro[2,4-dihydro-1H-naphthalene-3,5'-4H-imidazole]-2'-amine;(3S)-3'-methyl-8-pyrimidin-5-ylspiro[2,4-dihydro-1H-naphthalene-3,5'-4H-imidazole]-2'-amine;(3S)-3'-methyl-8-thiophen-3-ylspiro[2,4-dihydro-1H-naphthalene-3,5'-4H-imidazole]-2'-amine;(5S)-8'-phenylspiro[1,4-dihydroimidazole-5,3'-2,4-dihydro-1H-naphthalene]-2-amine;(5S)-8'-thiophen-3-ylspiro[1,4-dihydroimidazole-5,3'-2,4-dihydro-1H-naphthalene]-2-amine?
The InChIKey is MHUAXIPGALJAFG-XSNAKOEFSA-N. The full InChI is InChI=1S/2C18H20N4.C18H19N3.2C17H19N5.C17H19N3O.C17H19N3S.C17H17NO.C16H17N3O.C16H17N3S/c2*1-13-21-18(11-22(13)2)7-6-17-14(8-18)4-3-5-16(17)15-9-19-12-20-10-15;19-17-20-12-18(21-17)10-9-16-14(11-18)7-4-8-15(16)13-5-2-1-3-6-13;2*1-22-10-17(21-16(22)18)6-5-15-12(7-17)3-2-4-14(15)13-8-19-11-20-9-13;1-20-11-17(19-16(20)18)8-7-13-12(10-17)4-2-5-14(13)15-6-3-9-21-15;1-20-11-17(19-16(20)18)7-5-15-12(9-17)3-2-4-14(15)13-6-8-21-10-13;1-4-13-12-17(8-3-10-18-17)9-7-14(13)15(5-1)16-6-2-11-19-16;17-15-18-10-16(19-15)7-6-12-11(9-16)3-1-4-13(12)14-5-2-8-20-14;17-15-18-10-16(19-15)6-4-14-11(8-16)2-1-3-13(14)12-5-7-20-9-12/h2*3-5,9-10,12H,6-8,11H2,1-2H3;1-8H,9-12H2,(H3,19,20,21);2*2-4,8-9,11H,5-7,10H2,1H3,(H2,18,21);2-6,9H,7-8,10-11H2,1H3,(H2,18,19);2-4,6,8,10H,5,7,9,11H2,1H3,(H2,18,19);1-2,4-6,10-11H,3,7-9,12H2;1-5,8H,6-7,9-10H2,(H3,17,18,19);1-3,5,7,9H,4,6,8,10H2,(H3,17,18,19)/t3*18-;5*17-;2*16-/m1001000000/s1.
What are the key properties of (3R)-2',3'-dimethyl-8-pyrimidin-5-ylspiro[2,4-dihydro-1H-naphthalene-3,5'-4H-imidazole];(3S)-2',3'-dimethyl-8-pyrimidin-5-ylspiro[2,4-dihydro-1H-naphthalene-3,5'-4H-imidazole];(3S)-8-(furan-2-yl)-3'-methylspiro[2,4-dihydro-1H-naphthalene-3,5'-4H-imidazole]-2'-amine;(5S)-8'-(furan-2-yl)spiro[1,4-dihydroimidazole-5,3'-2,4-dihydro-1H-naphthalene]-2-amine;(3R)-8-(furan-2-yl)spiro[2,4-dihydro-1H-naphthalene-3,2'-3,4-dihydropyrrole];(3R)-3'-methyl-8-pyrimidin-5-ylspiro[2,4-dihydro-1H-naphthalene-3,5'-4H-imidazole]-2'-amine;(3S)-3'-methyl-8-pyrimidin-5-ylspiro[2,4-dihydro-1H-naphthalene-3,5'-4H-imidazole]-2'-amine;(3S)-3'-methyl-8-thiophen-3-ylspiro[2,4-dihydro-1H-naphthalene-3,5'-4H-imidazole]-2'-amine;(5S)-8'-phenylspiro[1,4-dihydroimidazole-5,3'-2,4-dihydro-1H-naphthalene]-2-amine;(5S)-8'-thiophen-3-ylspiro[1,4-dihydroimidazole-5,3'-2,4-dihydro-1H-naphthalene]-2-amine?
(3R)-2',3'-dimethyl-8-pyrimidin-5-ylspiro[2,4-dihydro-1H-naphthalene-3,5'-4H-imidazole];(3S)-2',3'-dimethyl-8-pyrimidin-5-ylspiro[2,4-dihydro-1H-naphthalene-3,5'-4H-imidazole];(3S)-8-(furan-2-yl)-3'-methylspiro[2,4-dihydro-1H-naphthalene-3,5'-4H-imidazole]-2'-amine;(5S)-8'-(furan-2-yl)spiro[1,4-dihydroimidazole-5,3'-2,4-dihydro-1H-naphthalene]-2-amine;(3R)-8-(furan-2-yl)spiro[2,4-dihydro-1H-naphthalene-3,2'-3,4-dihydropyrrole];(3R)-3'-methyl-8-pyrimidin-5-ylspiro[2,4-dihydro-1H-naphthalene-3,5'-4H-imidazole]-2'-amine;(3S)-3'-methyl-8-pyrimidin-5-ylspiro[2,4-dihydro-1H-naphthalene-3,5'-4H-imidazole]-2'-amine;(3S)-3'-methyl-8-thiophen-3-ylspiro[2,4-dihydro-1H-naphthalene-3,5'-4H-imidazole]-2'-amine;(5S)-8'-phenylspiro[1,4-dihydroimidazole-5,3'-2,4-dihydro-1H-naphthalene]-2-amine;(5S)-8'-thiophen-3-ylspiro[1,4-dihydroimidazole-5,3'-2,4-dihydro-1H-naphthalene]-2-amine has a molecular weight of 2829.74 g/mol, XLogP of 25.26, 10 rotatable bonds, 10 hydrogen bond donors, and 39 hydrogen bond acceptors.
Where does this data come from?
All data for (3R)-2',3'-dimethyl-8-pyrimidin-5-ylspiro[2,4-dihydro-1H-naphthalene-3,5'-4H-imidazole];(3S)-2',3'-dimethyl-8-pyrimidin-5-ylspiro[2,4-dihydro-1H-naphthalene-3,5'-4H-imidazole];(3S)-8-(furan-2-yl)-3'-methylspiro[2,4-dihydro-1H-naphthalene-3,5'-4H-imidazole]-2'-amine;(5S)-8'-(furan-2-yl)spiro[1,4-dihydroimidazole-5,3'-2,4-dihydro-1H-naphthalene]-2-amine;(3R)-8-(furan-2-yl)spiro[2,4-dihydro-1H-naphthalene-3,2'-3,4-dihydropyrrole];(3R)-3'-methyl-8-pyrimidin-5-ylspiro[2,4-dihydro-1H-naphthalene-3,5'-4H-imidazole]-2'-amine;(3S)-3'-methyl-8-pyrimidin-5-ylspiro[2,4-dihydro-1H-naphthalene-3,5'-4H-imidazole]-2'-amine;(3S)-3'-methyl-8-thiophen-3-ylspiro[2,4-dihydro-1H-naphthalene-3,5'-4H-imidazole]-2'-amine;(5S)-8'-phenylspiro[1,4-dihydroimidazole-5,3'-2,4-dihydro-1H-naphthalene]-2-amine;(5S)-8'-thiophen-3-ylspiro[1,4-dihydroimidazole-5,3'-2,4-dihydro-1H-naphthalene]-2-amine is sourced from PubChem (CID 159570783), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).