2-[6-(3,4-dimethoxyphenyl)-2-methylimidazo[1,2-a]pyridin-3-yl]-4-phenyl-5-(1H-1,2,4-triazol-5-yl)-1,3-thiazole;2-(6-ethenyl-2-methylimidazo[1,2-a]pyridin-3-yl)-5-(4H-imidazol-2-yl)-4-phenyl-1,3-thiazole;2-[6-(2-fluoro-6-methoxyphenyl)-2-methylimidazo[1,2-a]pyridin-3-yl]-5-(4H-imidazol-2-yl)-4-phenyl-1,3-thiazole;5-(4H-imidazol-2-yl)-2-[2-methyl-6-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyridin-3-yl]-4-phenyl-1,3-thiazole

C100H78FN23O3S4 — CID 159578634

About 2-[6-(3,4-dimethoxyphenyl)-2-methylimidazo[1,2-a]pyridin-3-yl]-4-phenyl-5-(1H-1,2,4-triazol-5-yl)-1,3-thiazole;2-(6-ethenyl-2-methylimidazo[1,2-a]pyridin-3-yl)-5-(4H-imidazol-2-yl)-4-phenyl-1,3-thiazole;2-[6-(2-fluoro-6-methoxyphenyl)-2-methylimidazo[1,2-a]pyridin-3-yl]-5-(4H-imidazol-2-yl)-4-phenyl-1,3-thiazole;5-(4H-imidazol-2-yl)-2-[2-methyl-6-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyridin-3-yl]-4-phenyl-1,3-thiazole

2-[6-(3,4-dimethoxyphenyl)-2-methylimidazo[1,2-a]pyridin-3-yl]-4-phenyl-5-(1H-1,2,4-triazol-5-yl)-1,3-thiazole;2-(6-ethenyl-2-methylimidazo[1,2-a]pyridin-3-yl)-5-(4H-imidazol-2-yl)-4-phenyl-1,3-thiazole;2-[6-(2-fluoro-6-methoxyphenyl)-2-methylimidazo[1,2-a]pyridin-3-yl]-5-(4H-imidazol-2-yl)-4-phenyl-1,3-thiazole;5-(4H-imidazol-2-yl)-2-[2-methyl-6-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyridin-3-yl]-4-phenyl-1,3-thiazole (PubChem CID 159578634) has the molecular formula C100H78FN23O3S4 and a molecular weight of 1797.15 g/mol. Its IUPAC name is 2-[6-(3,4-dimethoxyphenyl)-2-methylimidazo[1,2-a]pyridin-3-yl]-4-phenyl-5-(1H-1,2,4-triazol-5-yl)-1,3-thiazole;2-(6-ethenyl-2-methylimidazo[1,2-a]pyridin-3-yl)-5-(4H-imidazol-2-yl)-4-phenyl-1,3-thiazole;2-[6-(2-fluoro-6-methoxyphenyl)-2-methylimidazo[1,2-a]pyridin-3-yl]-5-(4H-imidazol-2-yl)-4-phenyl-1,3-thiazole;5-(4H-imidazol-2-yl)-2-[2-methyl-6-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyridin-3-yl]-4-phenyl-1,3-thiazole.

Molecular Properties

• Compound Name: 2-[6-(3,4-dimethoxyphenyl)-2-methylimidazo[1,2-a]pyridin-3-yl]-4-phenyl-5-(1H-1,2,4-triazol-5-yl)-1,3-thiazole;2-(6-ethenyl-2-methylimidazo[1,2-a]pyridin-3-yl)-5-(4H-imidazol-2-yl)-4-phenyl-1,3-thiazole;2-[6-(2-fluoro-6-methoxyphenyl)-2-methylimidazo[1,2-a]pyridin-3-yl]-5-(4H-imidazol-2-yl)-4-phenyl-1,3-thiazole;5-(4H-imidazol-2-yl)-2-[2-methyl-6-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyridin-3-yl]-4-phenyl-1,3-thiazole
• PubChem CID: 159578634
• Molecular Formula: C100H78FN23O3S4
• Molecular Weight: 1797.15 g/mol
• Exact Mass: 1795.55
• IUPAC Name: 2-[6-(3,4-dimethoxyphenyl)-2-methylimidazo[1,2-a]pyridin-3-yl]-4-phenyl-5-(1H-1,2,4-triazol-5-yl)-1,3-thiazole;2-(6-ethenyl-2-methylimidazo[1,2-a]pyridin-3-yl)-5-(4H-imidazol-2-yl)-4-phenyl-1,3-thiazole;2-[6-(2-fluoro-6-methoxyphenyl)-2-methylimidazo[1,2-a]pyridin-3-yl]-5-(4H-imidazol-2-yl)-4-phenyl-1,3-thiazole;5-(4H-imidazol-2-yl)-2-[2-methyl-6-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyridin-3-yl]-4-phenyl-1,3-thiazole
• SMILES: C=Cc1ccc2nc(C)c(-c3nc(-c4ccccc4)c(C4=NCC=N4)s3)n2c1.COc1ccc(-c2ccc3nc(C)c(-c4nc(-c5ccccc5)c(-c5ncn[nH]5)s4)n3c2)cc1OC.COc1cccc(F)c1-c1ccc2nc(C)c(-c3nc(-c4ccccc4)c(C4=NCC=N4)s3)n2c1.Cc1nc2ccc(-c3cnn(C)c3)cn2c1-c1nc(-c2ccccc2)c(C2=NCC=N2)s1
• InChI: InChI=1S/C27H20FN5OS.C27H22N6O2S.C24H19N7S.C22H17N5S/c1-16-24(27-32-23(17-7-4-3-5-8-17)25(35-27)26-29-13-14-30-26)33-15-18(11-12-21(33)31-16)22-19(28)9-6-10-20(22)34-2;1-16-24(27-31-23(17-7-5-4-6-8-17)25(36-27)26-28-15-29-32-26)33-14-19(10-12-22(33)30-16)18-9-11-20(34-2)21(13-18)35-3;1-15-21(31-14-17(8-9-19(31)28-15)18-12-27-30(2)13-18)24-29-20(16-6-4-3-5-7-16)22(32-24)23-25-10-11-26-23;1-3-15-9-10-17-25-14(2)19(27(17)13-15)22-26-18(16-7-5-4-6-8-16)20(28-22)21-23-11-12-24-21/h3-13,15H,14H2,1-2H3;4-15H,1-3H3,(H,28,29,32);3-10,12-14H,11H2,1-2H3;3-11,13H,1,12H2,2H3
• InChIKey: MISMYBDCLSSKMQ-UHFFFAOYSA-N
• XLogP: 21.55
• TPSA: 282.00 Ų
• H-Bond Donors: 1
• H-Bond Acceptors: 29
• Rotatable Bonds: 19
• Heavy Atoms: 131
• Complexity: —

Lipinski Rule of Five

3 violations

Rule	Value
MW ≤ 500	1797.15
LogP ≤ 5	21.55
H-Bond Donors ≤ 5	1
H-Bond Acceptors ≤ 10	29

Frequently Asked Questions

What is the IUPAC name of 2-[6-(3,4-dimethoxyphenyl)-2-methylimidazo[1,2-a]pyridin-3-yl]-4-phenyl-5-(1H-1,2,4-triazol-5-yl)-1,3-thiazole;2-(6-ethenyl-2-methylimidazo[1,2-a]pyridin-3-yl)-5-(4H-imidazol-2-yl)-4-phenyl-1,3-thiazole;2-[6-(2-fluoro-6-methoxyphenyl)-2-methylimidazo[1,2-a]pyridin-3-yl]-5-(4H-imidazol-2-yl)-4-phenyl-1,3-thiazole;5-(4H-imidazol-2-yl)-2-[2-methyl-6-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyridin-3-yl]-4-phenyl-1,3-thiazole?

The IUPAC name of 2-[6-(3,4-dimethoxyphenyl)-2-methylimidazo[1,2-a]pyridin-3-yl]-4-phenyl-5-(1H-1,2,4-triazol-5-yl)-1,3-thiazole;2-(6-ethenyl-2-methylimidazo[1,2-a]pyridin-3-yl)-5-(4H-imidazol-2-yl)-4-phenyl-1,3-thiazole;2-[6-(2-fluoro-6-methoxyphenyl)-2-methylimidazo[1,2-a]pyridin-3-yl]-5-(4H-imidazol-2-yl)-4-phenyl-1,3-thiazole;5-(4H-imidazol-2-yl)-2-[2-methyl-6-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyridin-3-yl]-4-phenyl-1,3-thiazole (CID 159578634) is 2-[6-(3,4-dimethoxyphenyl)-2-methylimidazo[1,2-a]pyridin-3-yl]-4-phenyl-5-(1H-1,2,4-triazol-5-yl)-1,3-thiazole;2-(6-ethenyl-2-methylimidazo[1,2-a]pyridin-3-yl)-5-(4H-imidazol-2-yl)-4-phenyl-1,3-thiazole;2-[6-(2-fluoro-6-methoxyphenyl)-2-methylimidazo[1,2-a]pyridin-3-yl]-5-(4H-imidazol-2-yl)-4-phenyl-1,3-thiazole;5-(4H-imidazol-2-yl)-2-[2-methyl-6-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyridin-3-yl]-4-phenyl-1,3-thiazole.

What is the SMILES notation for 2-[6-(3,4-dimethoxyphenyl)-2-methylimidazo[1,2-a]pyridin-3-yl]-4-phenyl-5-(1H-1,2,4-triazol-5-yl)-1,3-thiazole;2-(6-ethenyl-2-methylimidazo[1,2-a]pyridin-3-yl)-5-(4H-imidazol-2-yl)-4-phenyl-1,3-thiazole;2-[6-(2-fluoro-6-methoxyphenyl)-2-methylimidazo[1,2-a]pyridin-3-yl]-5-(4H-imidazol-2-yl)-4-phenyl-1,3-thiazole;5-(4H-imidazol-2-yl)-2-[2-methyl-6-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyridin-3-yl]-4-phenyl-1,3-thiazole?

The canonical SMILES for 2-[6-(3,4-dimethoxyphenyl)-2-methylimidazo[1,2-a]pyridin-3-yl]-4-phenyl-5-(1H-1,2,4-triazol-5-yl)-1,3-thiazole;2-(6-ethenyl-2-methylimidazo[1,2-a]pyridin-3-yl)-5-(4H-imidazol-2-yl)-4-phenyl-1,3-thiazole;2-[6-(2-fluoro-6-methoxyphenyl)-2-methylimidazo[1,2-a]pyridin-3-yl]-5-(4H-imidazol-2-yl)-4-phenyl-1,3-thiazole;5-(4H-imidazol-2-yl)-2-[2-methyl-6-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyridin-3-yl]-4-phenyl-1,3-thiazole is C=Cc1ccc2nc(C)c(-c3nc(-c4ccccc4)c(C4=NCC=N4)s3)n2c1.COc1ccc(-c2ccc3nc(C)c(-c4nc(-c5ccccc5)c(-c5ncn[nH]5)s4)n3c2)cc1OC.COc1cccc(F)c1-c1ccc2nc(C)c(-c3nc(-c4ccccc4)c(C4=NCC=N4)s3)n2c1.Cc1nc2ccc(-c3cnn(C)c3)cn2c1-c1nc(-c2ccccc2)c(C2=NCC=N2)s1.

What is the InChIKey of 2-[6-(3,4-dimethoxyphenyl)-2-methylimidazo[1,2-a]pyridin-3-yl]-4-phenyl-5-(1H-1,2,4-triazol-5-yl)-1,3-thiazole;2-(6-ethenyl-2-methylimidazo[1,2-a]pyridin-3-yl)-5-(4H-imidazol-2-yl)-4-phenyl-1,3-thiazole;2-[6-(2-fluoro-6-methoxyphenyl)-2-methylimidazo[1,2-a]pyridin-3-yl]-5-(4H-imidazol-2-yl)-4-phenyl-1,3-thiazole;5-(4H-imidazol-2-yl)-2-[2-methyl-6-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyridin-3-yl]-4-phenyl-1,3-thiazole?

The InChIKey is MISMYBDCLSSKMQ-UHFFFAOYSA-N. The full InChI is InChI=1S/C27H20FN5OS.C27H22N6O2S.C24H19N7S.C22H17N5S/c1-16-24(27-32-23(17-7-4-3-5-8-17)25(35-27)26-29-13-14-30-26)33-15-18(11-12-21(33)31-16)22-19(28)9-6-10-20(22)34-2;1-16-24(27-31-23(17-7-5-4-6-8-17)25(36-27)26-28-15-29-32-26)33-14-19(10-12-22(33)30-16)18-9-11-20(34-2)21(13-18)35-3;1-15-21(31-14-17(8-9-19(31)28-15)18-12-27-30(2)13-18)24-29-20(16-6-4-3-5-7-16)22(32-24)23-25-10-11-26-23;1-3-15-9-10-17-25-14(2)19(27(17)13-15)22-26-18(16-7-5-4-6-8-16)20(28-22)21-23-11-12-24-21/h3-13,15H,14H2,1-2H3;4-15H,1-3H3,(H,28,29,32);3-10,12-14H,11H2,1-2H3;3-11,13H,1,12H2,2H3.

What are the key properties of 2-[6-(3,4-dimethoxyphenyl)-2-methylimidazo[1,2-a]pyridin-3-yl]-4-phenyl-5-(1H-1,2,4-triazol-5-yl)-1,3-thiazole;2-(6-ethenyl-2-methylimidazo[1,2-a]pyridin-3-yl)-5-(4H-imidazol-2-yl)-4-phenyl-1,3-thiazole;2-[6-(2-fluoro-6-methoxyphenyl)-2-methylimidazo[1,2-a]pyridin-3-yl]-5-(4H-imidazol-2-yl)-4-phenyl-1,3-thiazole;5-(4H-imidazol-2-yl)-2-[2-methyl-6-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyridin-3-yl]-4-phenyl-1,3-thiazole?

2-[6-(3,4-dimethoxyphenyl)-2-methylimidazo[1,2-a]pyridin-3-yl]-4-phenyl-5-(1H-1,2,4-triazol-5-yl)-1,3-thiazole;2-(6-ethenyl-2-methylimidazo[1,2-a]pyridin-3-yl)-5-(4H-imidazol-2-yl)-4-phenyl-1,3-thiazole;2-[6-(2-fluoro-6-methoxyphenyl)-2-methylimidazo[1,2-a]pyridin-3-yl]-5-(4H-imidazol-2-yl)-4-phenyl-1,3-thiazole;5-(4H-imidazol-2-yl)-2-[2-methyl-6-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyridin-3-yl]-4-phenyl-1,3-thiazole has a molecular weight of 1797.15 g/mol, XLogP of 21.55, 19 rotatable bonds, 1 hydrogen bond donors, and 29 hydrogen bond acceptors.

Where does this data come from?

All data for 2-[6-(3,4-dimethoxyphenyl)-2-methylimidazo[1,2-a]pyridin-3-yl]-4-phenyl-5-(1H-1,2,4-triazol-5-yl)-1,3-thiazole;2-(6-ethenyl-2-methylimidazo[1,2-a]pyridin-3-yl)-5-(4H-imidazol-2-yl)-4-phenyl-1,3-thiazole;2-[6-(2-fluoro-6-methoxyphenyl)-2-methylimidazo[1,2-a]pyridin-3-yl]-5-(4H-imidazol-2-yl)-4-phenyl-1,3-thiazole;5-(4H-imidazol-2-yl)-2-[2-methyl-6-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyridin-3-yl]-4-phenyl-1,3-thiazole is sourced from PubChem (CID 159578634), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).