(4R)-8-[8-(2-amino-5-chloro-4-pyridinyl)-7-methylimidazo[1,2-c]pyrimidin-5-yl]-N-methyl-8-azaspiro[4.5]decan-4-amine;(4R)-8-[8-[(2-amino-3-chloro-4-pyridinyl)sulfanyl]-7-methylimidazo[1,2-c]pyrimidin-5-yl]-N-methyl-8-azaspiro[4.5]decan-4-amine;(4R)-8-[8-[[6-amino-2-(trifluoromethyl)-3-pyridinyl]sulfanyl]-7-methylimidazo[1,2-c]pyrimidin-5-yl]-N-methyl-8-azaspiro[4.5]decan-4-amine;(4R)-8-[8-(3,5-dimethyl-1,2-oxazol-4-yl)-7-methylimidazo[1,2-c]pyrimidin-5-yl]-N-methyl-8-azaspiro[4.5]decan-4-amine;(4R)-N-methyl-8-[7-methyl-8-[2-(trifluoromethyl)-3-pyridinyl]imidazo[1,2-c]pyrimidin-5-yl]-8-azaspiro[4.5]decan-4-amine

C112H141Cl2F6N33OS2 — CID 159582524

IUPAC(4R)-8-[8-(2-amino-5-chloro-4-pyridinyl)-7-methylimidazo[1,2-c]pyrimidin-5-yl]-N-methyl-8-azaspiro[4.5]decan-4-amine;(4R)-8-[8-[(2-amino-3-chloro-4-pyridinyl)sulfanyl]-7-methylimidazo[1,2-c]pyrimidin-5-yl]-N-methyl-8-azaspiro[4.5]decan-4-amine;(4R)-8-[8-[[6-amino-2-(trifluoromethyl)-3-pyridinyl]sulfanyl]-7-methylimidazo[1,2-c]pyrimidin-5-yl]-N-methyl-8-azaspiro[4.5]decan-4-amine;(4R)-8-[8-(3,5-dimethyl-1,2-oxazol-4-yl)-7-methylimidazo[1,2-c]pyrimidin-5-yl]-N-methyl-8-azaspiro[4.5]decan-4-amine;(4R)-N-methyl-8-[7-methyl-8-[2-(trifluoromethyl)-3-pyridinyl]imidazo[1,2-c]pyrimidin-5-yl]-8-azaspiro[4.5]decan-4-amine
SMILESCN[C@@H]1CCCC12CCN(c1nc(C)c(-c3c(C)noc3C)c3nccn13)CC2.CN[C@@H]1CCCC12CCN(c1nc(C)c(-c3cc(N)ncc3Cl)c3nccn13)CC2.CN[C@@H]1CCCC12CCN(c1nc(C)c(-c3cccnc3C(F)(F)F)c3nccn13)CC2.CN[C@@H]1CCCC12CCN(c1nc(C)c(Sc3ccc(N)nc3C(F)(F)F)c3nccn13)CC2.CN[C@@H]1CCCC12CCN(c1nc(C)c(Sc3ccnc(N)c3Cl)c3nccn13)CC2
InChIInChI=1S/C23H28F3N7S.C23H27F3N6.C22H28ClN7S.C22H28ClN7.C22H30N6O/c1-14-18(34-15-5-6-17(27)31-19(15)23(24,25)26)20-29-10-13-33(20)21(30-14)32-11-8-22(9-12-32)7-3-4-16(22)28-2;1-15-18(16-5-4-10-28-19(16)23(24,25)26)20-29-11-14-32(20)21(30-15)31-12-8-22(9-13-31)7-3-6-17(22)27-2;1-14-18(31-15-5-9-26-19(24)17(15)23)20-27-10-13-30(20)21(28-14)29-11-7-22(8-12-29)6-3-4-16(22)25-2;1-14-19(15-12-18(24)27-13-16(15)23)20-26-8-11-30(20)21(28-14)29-9-6-22(7-10-29)5-3-4-17(22)25-2;1-14-19(18-15(2)26-29-16(18)3)20-24-10-13-28(20)21(25-14)27-11-8-22(9-12-27)7-5-6-17(22)23-4/h5-6,10,13,16,28H,3-4,7-9,11-12H2,1-2H3,(H2,27,31);4-5,10-11,14,17,27H,3,6-9,12-13H2,1-2H3;5,9-10,13,16,25H,3-4,6-8,11-12H2,1-2H3,(H2,24,26);8,11-13,17,25H,3-7,9-10H2,1-2H3,(H2,24,27);10,13,17,23H,5-9,11-12H2,1-4H3/t16-;17-;16-;2*17-/m11111/s1
InChIKeyMJEXOLRWVMGYTG-HZPOMJFPSA-N
MW2214.62 g/mol
LogP20.56
Rot. Bonds17

About (4R)-8-[8-(2-amino-5-chloro-4-pyridinyl)-7-methylimidazo[1,2-c]pyrimidin-5-yl]-N-methyl-8-azaspiro[4.5]decan-4-amine;(4R)-8-[8-[(2-amino-3-chloro-4-pyridinyl)sulfanyl]-7-methylimidazo[1,2-c]pyrimidin-5-yl]-N-methyl-8-azaspiro[4.5]decan-4-amine;(4R)-8-[8-[[6-amino-2-(trifluoromethyl)-3-pyridinyl]sulfanyl]-7-methylimidazo[1,2-c]pyrimidin-5-yl]-N-methyl-8-azaspiro[4.5]decan-4-amine;(4R)-8-[8-(3,5-dimethyl-1,2-oxazol-4-yl)-7-methylimidazo[1,2-c]pyrimidin-5-yl]-N-methyl-8-azaspiro[4.5]decan-4-amine;(4R)-N-methyl-8-[7-methyl-8-[2-(trifluoromethyl)-3-pyridinyl]imidazo[1,2-c]pyrimidin-5-yl]-8-azaspiro[4.5]decan-4-amine

(4R)-8-[8-(2-amino-5-chloro-4-pyridinyl)-7-methylimidazo[1,2-c]pyrimidin-5-yl]-N-methyl-8-azaspiro[4.5]decan-4-amine;(4R)-8-[8-[(2-amino-3-chloro-4-pyridinyl)sulfanyl]-7-methylimidazo[1,2-c]pyrimidin-5-yl]-N-methyl-8-azaspiro[4.5]decan-4-amine;(4R)-8-[8-[[6-amino-2-(trifluoromethyl)-3-pyridinyl]sulfanyl]-7-methylimidazo[1,2-c]pyrimidin-5-yl]-N-methyl-8-azaspiro[4.5]decan-4-amine;(4R)-8-[8-(3,5-dimethyl-1,2-oxazol-4-yl)-7-methylimidazo[1,2-c]pyrimidin-5-yl]-N-methyl-8-azaspiro[4.5]decan-4-amine;(4R)-N-methyl-8-[7-methyl-8-[2-(trifluoromethyl)-3-pyridinyl]imidazo[1,2-c]pyrimidin-5-yl]-8-azaspiro[4.5]decan-4-amine (PubChem CID 159582524) has the molecular formula C112H141Cl2F6N33OS2 and a molecular weight of 2214.62 g/mol. Its IUPAC name is (4R)-8-[8-(2-amino-5-chloro-4-pyridinyl)-7-methylimidazo[1,2-c]pyrimidin-5-yl]-N-methyl-8-azaspiro[4.5]decan-4-amine;(4R)-8-[8-[(2-amino-3-chloro-4-pyridinyl)sulfanyl]-7-methylimidazo[1,2-c]pyrimidin-5-yl]-N-methyl-8-azaspiro[4.5]decan-4-amine;(4R)-8-[8-[[6-amino-2-(trifluoromethyl)-3-pyridinyl]sulfanyl]-7-methylimidazo[1,2-c]pyrimidin-5-yl]-N-methyl-8-azaspiro[4.5]decan-4-amine;(4R)-8-[8-(3,5-dimethyl-1,2-oxazol-4-yl)-7-methylimidazo[1,2-c]pyrimidin-5-yl]-N-methyl-8-azaspiro[4.5]decan-4-amine;(4R)-N-methyl-8-[7-methyl-8-[2-(trifluoromethyl)-3-pyridinyl]imidazo[1,2-c]pyrimidin-5-yl]-8-azaspiro[4.5]decan-4-amine.

Molecular Properties

Compound Name(4R)-8-[8-(2-amino-5-chloro-4-pyridinyl)-7-methylimidazo[1,2-c]pyrimidin-5-yl]-N-methyl-8-azaspiro[4.5]decan-4-amine;(4R)-8-[8-[(2-amino-3-chloro-4-pyridinyl)sulfanyl]-7-methylimidazo[1,2-c]pyrimidin-5-yl]-N-methyl-8-azaspiro[4.5]decan-4-amine;(4R)-8-[8-[[6-amino-2-(trifluoromethyl)-3-pyridinyl]sulfanyl]-7-methylimidazo[1,2-c]pyrimidin-5-yl]-N-methyl-8-azaspiro[4.5]decan-4-amine;(4R)-8-[8-(3,5-dimethyl-1,2-oxazol-4-yl)-7-methylimidazo[1,2-c]pyrimidin-5-yl]-N-methyl-8-azaspiro[4.5]decan-4-amine;(4R)-N-methyl-8-[7-methyl-8-[2-(trifluoromethyl)-3-pyridinyl]imidazo[1,2-c]pyrimidin-5-yl]-8-azaspiro[4.5]decan-4-amine
PubChem CID159582524
Molecular FormulaC112H141Cl2F6N33OS2
Molecular Weight2214.62 g/mol
Exact Mass2212.07
IUPAC Name(4R)-8-[8-(2-amino-5-chloro-4-pyridinyl)-7-methylimidazo[1,2-c]pyrimidin-5-yl]-N-methyl-8-azaspiro[4.5]decan-4-amine;(4R)-8-[8-[(2-amino-3-chloro-4-pyridinyl)sulfanyl]-7-methylimidazo[1,2-c]pyrimidin-5-yl]-N-methyl-8-azaspiro[4.5]decan-4-amine;(4R)-8-[8-[[6-amino-2-(trifluoromethyl)-3-pyridinyl]sulfanyl]-7-methylimidazo[1,2-c]pyrimidin-5-yl]-N-methyl-8-azaspiro[4.5]decan-4-amine;(4R)-8-[8-(3,5-dimethyl-1,2-oxazol-4-yl)-7-methylimidazo[1,2-c]pyrimidin-5-yl]-N-methyl-8-azaspiro[4.5]decan-4-amine;(4R)-N-methyl-8-[7-methyl-8-[2-(trifluoromethyl)-3-pyridinyl]imidazo[1,2-c]pyrimidin-5-yl]-8-azaspiro[4.5]decan-4-amine
SMILESCN[C@@H]1CCCC12CCN(c1nc(C)c(-c3c(C)noc3C)c3nccn13)CC2.CN[C@@H]1CCCC12CCN(c1nc(C)c(-c3cc(N)ncc3Cl)c3nccn13)CC2.CN[C@@H]1CCCC12CCN(c1nc(C)c(-c3cccnc3C(F)(F)F)c3nccn13)CC2.CN[C@@H]1CCCC12CCN(c1nc(C)c(Sc3ccc(N)nc3C(F)(F)F)c3nccn13)CC2.CN[C@@H]1CCCC12CCN(c1nc(C)c(Sc3ccnc(N)c3Cl)c3nccn13)CC2
InChIInChI=1S/C23H28F3N7S.C23H27F3N6.C22H28ClN7S.C22H28ClN7.C22H30N6O/c1-14-18(34-15-5-6-17(27)31-19(15)23(24,25)26)20-29-10-13-33(20)21(30-14)32-11-8-22(9-12-32)7-3-4-16(22)28-2;1-15-18(16-5-4-10-28-19(16)23(24,25)26)20-29-11-14-32(20)21(30-15)31-12-8-22(9-13-31)7-3-6-17(22)27-2;1-14-18(31-15-5-9-26-19(24)17(15)23)20-27-10-13-30(20)21(28-14)29-11-7-22(8-12-29)6-3-4-16(22)25-2;1-14-19(15-12-18(24)27-13-16(15)23)20-26-8-11-30(20)21(28-14)29-9-6-22(7-10-29)5-3-4-17(22)25-2;1-14-19(18-15(2)26-29-16(18)3)20-24-10-13-28(20)21(25-14)27-11-8-22(9-12-27)7-5-6-17(22)23-4/h5-6,10,13,16,28H,3-4,7-9,11-12H2,1-2H3,(H2,27,31);4-5,10-11,14,17,27H,3,6-9,12-13H2,1-2H3;5,9-10,13,16,25H,3-4,6-8,11-12H2,1-2H3,(H2,24,26);8,11-13,17,25H,3-7,9-10H2,1-2H3,(H2,24,27);10,13,17,23H,5-9,11-12H2,1-4H3/t16-;17-;16-;2*17-/m11111/s1
InChIKeyMJEXOLRWVMGYTG-HZPOMJFPSA-N
XLogP20.56
TPSA382.95 Ų
H-Bond Donors8
H-Bond Acceptors36
Rotatable Bonds17
Heavy Atoms156
Complexity—

Lipinski Rule of Five

4 violations

RuleValue
MW ≤ 5002214.62
LogP ≤ 520.56
H-Bond Donors ≤ 58
H-Bond Acceptors ≤ 1036

Analyze (4R)-8-[8-(2-amino-5-chloro-4-pyridinyl)-7-methylimidazo[1,2-c]pyrimidin-5-yl]-N-methyl-8-azaspiro[4.5]decan-4-amine;(4R)-8-[8-[(2-amino-3-chloro-4-pyridinyl)sulfanyl]-7-methylimidazo[1,2-c]pyrimidin-5-yl]-N-methyl-8-azaspiro[4.5]decan-4-amine;(4R)-8-[8-[[6-amino-2-(trifluoromethyl)-3-pyridinyl]sulfanyl]-7-methylimidazo[1,2-c]pyrimidin-5-yl]-N-methyl-8-azaspiro[4.5]decan-4-amine;(4R)-8-[8-(3,5-dimethyl-1,2-oxazol-4-yl)-7-methylimidazo[1,2-c]pyrimidin-5-yl]-N-methyl-8-azaspiro[4.5]decan-4-amine;(4R)-N-methyl-8-[7-methyl-8-[2-(trifluoromethyl)-3-pyridinyl]imidazo[1,2-c]pyrimidin-5-yl]-8-azaspiro[4.5]decan-4-amine with MolForge

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Launch Full Analysis

Related Compounds

3-chloro-2-[(4,6-dimethylpyrimidin-2-yl)sulfanylmethyl]imidazo[1,2-a]pyridine;2-[(2-chloro-3-ethylimidazol-4-yl)methylsulfanyl]-4,6-dimethylpyrimidine;2-[(5-chloro-3-methylimidazol-4-yl)methylsulfanyl]-4,6-dimethylpyrimidine;2-[(2-chloro-3-propan-2-ylimidazol-4-yl)methylsulfanyl]-4,6-dimethylpyrimidine;2-[(3-cyclopentylimidazol-4-yl)methylsulfanyl]-4,6-dimethylpyrimidine;2-[(3,5-dichloro-4-pyridinyl)methylsulfanyl]-4,6-dimethylpyrimidine;4,6-dimethyl-2-[(1-methylimidazol-4-yl)methylsulfanyl]pyrimidine;4,6-dimethyl-2-[(1-propan-2-ylimidazol-2-yl)methylsulfanyl]pyrimidine;2-[(3-ethyl-5-methyl-1,2-oxazol-4-yl)methylsulfanyl]-4-methyl-1H-pyrimidin-6-one
CID 158395340
3-chloro-2-[(4,6-dimethylpyrimidin-2-yl)sulfanylmethyl]imidazo[1,2-a]pyridine;2-[(2-chloro-3-ethylimidazol-4-yl)methylsulfanyl]-4,6-dimethylpyrimidine;2-[(5-chloro-3-methylimidazol-4-yl)methylsulfanyl]-4,6-dimethylpyrimidine;2-[(2-chloro-3-propan-2-ylimidazol-4-yl)methylsulfanyl]-4,6-dimethylpyrimidine;2-[(3,5-dichloro-4-pyridinyl)methylsulfanyl]-4,6-dimethylpyrimidine;4,6-dimethyl-2-[[3-(2-methylpropyl)imidazol-4-yl]methylsulfanyl]pyrimidine;2-[(3-ethyl-5-methyl-1,2-oxazol-4-yl)methylsulfanyl]-4-methyl-1H-pyrimidin-6-one
CID 160994075

Frequently Asked Questions

What is the IUPAC name of (4R)-8-[8-(2-amino-5-chloro-4-pyridinyl)-7-methylimidazo[1,2-c]pyrimidin-5-yl]-N-methyl-8-azaspiro[4.5]decan-4-amine;(4R)-8-[8-[(2-amino-3-chloro-4-pyridinyl)sulfanyl]-7-methylimidazo[1,2-c]pyrimidin-5-yl]-N-methyl-8-azaspiro[4.5]decan-4-amine;(4R)-8-[8-[[6-amino-2-(trifluoromethyl)-3-pyridinyl]sulfanyl]-7-methylimidazo[1,2-c]pyrimidin-5-yl]-N-methyl-8-azaspiro[4.5]decan-4-amine;(4R)-8-[8-(3,5-dimethyl-1,2-oxazol-4-yl)-7-methylimidazo[1,2-c]pyrimidin-5-yl]-N-methyl-8-azaspiro[4.5]decan-4-amine;(4R)-N-methyl-8-[7-methyl-8-[2-(trifluoromethyl)-3-pyridinyl]imidazo[1,2-c]pyrimidin-5-yl]-8-azaspiro[4.5]decan-4-amine?
The IUPAC name of (4R)-8-[8-(2-amino-5-chloro-4-pyridinyl)-7-methylimidazo[1,2-c]pyrimidin-5-yl]-N-methyl-8-azaspiro[4.5]decan-4-amine;(4R)-8-[8-[(2-amino-3-chloro-4-pyridinyl)sulfanyl]-7-methylimidazo[1,2-c]pyrimidin-5-yl]-N-methyl-8-azaspiro[4.5]decan-4-amine;(4R)-8-[8-[[6-amino-2-(trifluoromethyl)-3-pyridinyl]sulfanyl]-7-methylimidazo[1,2-c]pyrimidin-5-yl]-N-methyl-8-azaspiro[4.5]decan-4-amine;(4R)-8-[8-(3,5-dimethyl-1,2-oxazol-4-yl)-7-methylimidazo[1,2-c]pyrimidin-5-yl]-N-methyl-8-azaspiro[4.5]decan-4-amine;(4R)-N-methyl-8-[7-methyl-8-[2-(trifluoromethyl)-3-pyridinyl]imidazo[1,2-c]pyrimidin-5-yl]-8-azaspiro[4.5]decan-4-amine (CID 159582524) is (4R)-8-[8-(2-amino-5-chloro-4-pyridinyl)-7-methylimidazo[1,2-c]pyrimidin-5-yl]-N-methyl-8-azaspiro[4.5]decan-4-amine;(4R)-8-[8-[(2-amino-3-chloro-4-pyridinyl)sulfanyl]-7-methylimidazo[1,2-c]pyrimidin-5-yl]-N-methyl-8-azaspiro[4.5]decan-4-amine;(4R)-8-[8-[[6-amino-2-(trifluoromethyl)-3-pyridinyl]sulfanyl]-7-methylimidazo[1,2-c]pyrimidin-5-yl]-N-methyl-8-azaspiro[4.5]decan-4-amine;(4R)-8-[8-(3,5-dimethyl-1,2-oxazol-4-yl)-7-methylimidazo[1,2-c]pyrimidin-5-yl]-N-methyl-8-azaspiro[4.5]decan-4-amine;(4R)-N-methyl-8-[7-methyl-8-[2-(trifluoromethyl)-3-pyridinyl]imidazo[1,2-c]pyrimidin-5-yl]-8-azaspiro[4.5]decan-4-amine.
What is the SMILES notation for (4R)-8-[8-(2-amino-5-chloro-4-pyridinyl)-7-methylimidazo[1,2-c]pyrimidin-5-yl]-N-methyl-8-azaspiro[4.5]decan-4-amine;(4R)-8-[8-[(2-amino-3-chloro-4-pyridinyl)sulfanyl]-7-methylimidazo[1,2-c]pyrimidin-5-yl]-N-methyl-8-azaspiro[4.5]decan-4-amine;(4R)-8-[8-[[6-amino-2-(trifluoromethyl)-3-pyridinyl]sulfanyl]-7-methylimidazo[1,2-c]pyrimidin-5-yl]-N-methyl-8-azaspiro[4.5]decan-4-amine;(4R)-8-[8-(3,5-dimethyl-1,2-oxazol-4-yl)-7-methylimidazo[1,2-c]pyrimidin-5-yl]-N-methyl-8-azaspiro[4.5]decan-4-amine;(4R)-N-methyl-8-[7-methyl-8-[2-(trifluoromethyl)-3-pyridinyl]imidazo[1,2-c]pyrimidin-5-yl]-8-azaspiro[4.5]decan-4-amine?
The canonical SMILES for (4R)-8-[8-(2-amino-5-chloro-4-pyridinyl)-7-methylimidazo[1,2-c]pyrimidin-5-yl]-N-methyl-8-azaspiro[4.5]decan-4-amine;(4R)-8-[8-[(2-amino-3-chloro-4-pyridinyl)sulfanyl]-7-methylimidazo[1,2-c]pyrimidin-5-yl]-N-methyl-8-azaspiro[4.5]decan-4-amine;(4R)-8-[8-[[6-amino-2-(trifluoromethyl)-3-pyridinyl]sulfanyl]-7-methylimidazo[1,2-c]pyrimidin-5-yl]-N-methyl-8-azaspiro[4.5]decan-4-amine;(4R)-8-[8-(3,5-dimethyl-1,2-oxazol-4-yl)-7-methylimidazo[1,2-c]pyrimidin-5-yl]-N-methyl-8-azaspiro[4.5]decan-4-amine;(4R)-N-methyl-8-[7-methyl-8-[2-(trifluoromethyl)-3-pyridinyl]imidazo[1,2-c]pyrimidin-5-yl]-8-azaspiro[4.5]decan-4-amine is CN[C@@H]1CCCC12CCN(c1nc(C)c(-c3c(C)noc3C)c3nccn13)CC2.CN[C@@H]1CCCC12CCN(c1nc(C)c(-c3cc(N)ncc3Cl)c3nccn13)CC2.CN[C@@H]1CCCC12CCN(c1nc(C)c(-c3cccnc3C(F)(F)F)c3nccn13)CC2.CN[C@@H]1CCCC12CCN(c1nc(C)c(Sc3ccc(N)nc3C(F)(F)F)c3nccn13)CC2.CN[C@@H]1CCCC12CCN(c1nc(C)c(Sc3ccnc(N)c3Cl)c3nccn13)CC2.
What is the InChIKey of (4R)-8-[8-(2-amino-5-chloro-4-pyridinyl)-7-methylimidazo[1,2-c]pyrimidin-5-yl]-N-methyl-8-azaspiro[4.5]decan-4-amine;(4R)-8-[8-[(2-amino-3-chloro-4-pyridinyl)sulfanyl]-7-methylimidazo[1,2-c]pyrimidin-5-yl]-N-methyl-8-azaspiro[4.5]decan-4-amine;(4R)-8-[8-[[6-amino-2-(trifluoromethyl)-3-pyridinyl]sulfanyl]-7-methylimidazo[1,2-c]pyrimidin-5-yl]-N-methyl-8-azaspiro[4.5]decan-4-amine;(4R)-8-[8-(3,5-dimethyl-1,2-oxazol-4-yl)-7-methylimidazo[1,2-c]pyrimidin-5-yl]-N-methyl-8-azaspiro[4.5]decan-4-amine;(4R)-N-methyl-8-[7-methyl-8-[2-(trifluoromethyl)-3-pyridinyl]imidazo[1,2-c]pyrimidin-5-yl]-8-azaspiro[4.5]decan-4-amine?
The InChIKey is MJEXOLRWVMGYTG-HZPOMJFPSA-N. The full InChI is InChI=1S/C23H28F3N7S.C23H27F3N6.C22H28ClN7S.C22H28ClN7.C22H30N6O/c1-14-18(34-15-5-6-17(27)31-19(15)23(24,25)26)20-29-10-13-33(20)21(30-14)32-11-8-22(9-12-32)7-3-4-16(22)28-2;1-15-18(16-5-4-10-28-19(16)23(24,25)26)20-29-11-14-32(20)21(30-15)31-12-8-22(9-13-31)7-3-6-17(22)27-2;1-14-18(31-15-5-9-26-19(24)17(15)23)20-27-10-13-30(20)21(28-14)29-11-7-22(8-12-29)6-3-4-16(22)25-2;1-14-19(15-12-18(24)27-13-16(15)23)20-26-8-11-30(20)21(28-14)29-9-6-22(7-10-29)5-3-4-17(22)25-2;1-14-19(18-15(2)26-29-16(18)3)20-24-10-13-28(20)21(25-14)27-11-8-22(9-12-27)7-5-6-17(22)23-4/h5-6,10,13,16,28H,3-4,7-9,11-12H2,1-2H3,(H2,27,31);4-5,10-11,14,17,27H,3,6-9,12-13H2,1-2H3;5,9-10,13,16,25H,3-4,6-8,11-12H2,1-2H3,(H2,24,26);8,11-13,17,25H,3-7,9-10H2,1-2H3,(H2,24,27);10,13,17,23H,5-9,11-12H2,1-4H3/t16-;17-;16-;2*17-/m11111/s1.
What are the key properties of (4R)-8-[8-(2-amino-5-chloro-4-pyridinyl)-7-methylimidazo[1,2-c]pyrimidin-5-yl]-N-methyl-8-azaspiro[4.5]decan-4-amine;(4R)-8-[8-[(2-amino-3-chloro-4-pyridinyl)sulfanyl]-7-methylimidazo[1,2-c]pyrimidin-5-yl]-N-methyl-8-azaspiro[4.5]decan-4-amine;(4R)-8-[8-[[6-amino-2-(trifluoromethyl)-3-pyridinyl]sulfanyl]-7-methylimidazo[1,2-c]pyrimidin-5-yl]-N-methyl-8-azaspiro[4.5]decan-4-amine;(4R)-8-[8-(3,5-dimethyl-1,2-oxazol-4-yl)-7-methylimidazo[1,2-c]pyrimidin-5-yl]-N-methyl-8-azaspiro[4.5]decan-4-amine;(4R)-N-methyl-8-[7-methyl-8-[2-(trifluoromethyl)-3-pyridinyl]imidazo[1,2-c]pyrimidin-5-yl]-8-azaspiro[4.5]decan-4-amine?
(4R)-8-[8-(2-amino-5-chloro-4-pyridinyl)-7-methylimidazo[1,2-c]pyrimidin-5-yl]-N-methyl-8-azaspiro[4.5]decan-4-amine;(4R)-8-[8-[(2-amino-3-chloro-4-pyridinyl)sulfanyl]-7-methylimidazo[1,2-c]pyrimidin-5-yl]-N-methyl-8-azaspiro[4.5]decan-4-amine;(4R)-8-[8-[[6-amino-2-(trifluoromethyl)-3-pyridinyl]sulfanyl]-7-methylimidazo[1,2-c]pyrimidin-5-yl]-N-methyl-8-azaspiro[4.5]decan-4-amine;(4R)-8-[8-(3,5-dimethyl-1,2-oxazol-4-yl)-7-methylimidazo[1,2-c]pyrimidin-5-yl]-N-methyl-8-azaspiro[4.5]decan-4-amine;(4R)-N-methyl-8-[7-methyl-8-[2-(trifluoromethyl)-3-pyridinyl]imidazo[1,2-c]pyrimidin-5-yl]-8-azaspiro[4.5]decan-4-amine has a molecular weight of 2214.62 g/mol, XLogP of 20.56, 17 rotatable bonds, 8 hydrogen bond donors, and 36 hydrogen bond acceptors.
Where does this data come from?
All data for (4R)-8-[8-(2-amino-5-chloro-4-pyridinyl)-7-methylimidazo[1,2-c]pyrimidin-5-yl]-N-methyl-8-azaspiro[4.5]decan-4-amine;(4R)-8-[8-[(2-amino-3-chloro-4-pyridinyl)sulfanyl]-7-methylimidazo[1,2-c]pyrimidin-5-yl]-N-methyl-8-azaspiro[4.5]decan-4-amine;(4R)-8-[8-[[6-amino-2-(trifluoromethyl)-3-pyridinyl]sulfanyl]-7-methylimidazo[1,2-c]pyrimidin-5-yl]-N-methyl-8-azaspiro[4.5]decan-4-amine;(4R)-8-[8-(3,5-dimethyl-1,2-oxazol-4-yl)-7-methylimidazo[1,2-c]pyrimidin-5-yl]-N-methyl-8-azaspiro[4.5]decan-4-amine;(4R)-N-methyl-8-[7-methyl-8-[2-(trifluoromethyl)-3-pyridinyl]imidazo[1,2-c]pyrimidin-5-yl]-8-azaspiro[4.5]decan-4-amine is sourced from PubChem (CID 159582524), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).