N-[5-(7-chloro-1H-indazol-5-yl)-3-cyano-6-(1-methylpyrazol-3-yl)pyrazin-2-yl]-2-cyclopentylethanesulfonamide;N-[5-(7-chloro-1H-indazol-5-yl)-3-cyano-6-(1-methylpyrazol-3-yl)pyrazin-2-yl]-1-(1-methylpyrrol-3-yl)methanesulfonamide;N-[5-(7-chloro-1H-indazol-5-yl)-3-cyano-6-(1-methylpyrazol-3-yl)pyrazin-2-yl]-2-(oxan-4-yl)ethanesulfonamide;N-[5-(7-chloro-1H-indazol-5-yl)-3-cyano-6-(1-methylpyrazol-3-yl)pyrazin-2-yl]-2-pyridin-3-ylethanesulfonamide;N-[5-(7-chloro-1H-indazol-5-yl)-3-cyano-6-(1-methylpyrazol-3-yl)pyrazin-2-yl]-1-pyrimidin-5-ylmethanesulfonamide

C112H97Cl5N44O11S5 — CID 159593284

About N-[5-(7-chloro-1H-indazol-5-yl)-3-cyano-6-(1-methylpyrazol-3-yl)pyrazin-2-yl]-2-cyclopentylethanesulfonamide;N-[5-(7-chloro-1H-indazol-5-yl)-3-cyano-6-(1-methylpyrazol-3-yl)pyrazin-2-yl]-1-(1-methylpyrrol-3-yl)methanesulfonamide;N-[5-(7-chloro-1H-indazol-5-yl)-3-cyano-6-(1-methylpyrazol-3-yl)pyrazin-2-yl]-2-(oxan-4-yl)ethanesulfonamide;N-[5-(7-chloro-1H-indazol-5-yl)-3-cyano-6-(1-methylpyrazol-3-yl)pyrazin-2-yl]-2-pyridin-3-ylethanesulfonamide;N-[5-(7-chloro-1H-indazol-5-yl)-3-cyano-6-(1-methylpyrazol-3-yl)pyrazin-2-yl]-1-pyrimidin-5-ylmethanesulfonamide

N-[5-(7-chloro-1H-indazol-5-yl)-3-cyano-6-(1-methylpyrazol-3-yl)pyrazin-2-yl]-2-cyclopentylethanesulfonamide;N-[5-(7-chloro-1H-indazol-5-yl)-3-cyano-6-(1-methylpyrazol-3-yl)pyrazin-2-yl]-1-(1-methylpyrrol-3-yl)methanesulfonamide;N-[5-(7-chloro-1H-indazol-5-yl)-3-cyano-6-(1-methylpyrazol-3-yl)pyrazin-2-yl]-2-(oxan-4-yl)ethanesulfonamide;N-[5-(7-chloro-1H-indazol-5-yl)-3-cyano-6-(1-methylpyrazol-3-yl)pyrazin-2-yl]-2-pyridin-3-ylethanesulfonamide;N-[5-(7-chloro-1H-indazol-5-yl)-3-cyano-6-(1-methylpyrazol-3-yl)pyrazin-2-yl]-1-pyrimidin-5-ylmethanesulfonamide (PubChem CID 159593284) has the molecular formula C112H97Cl5N44O11S5 and a molecular weight of 2572.90 g/mol. Its IUPAC name is N-[5-(7-chloro-1H-indazol-5-yl)-3-cyano-6-(1-methylpyrazol-3-yl)pyrazin-2-yl]-2-cyclopentylethanesulfonamide;N-[5-(7-chloro-1H-indazol-5-yl)-3-cyano-6-(1-methylpyrazol-3-yl)pyrazin-2-yl]-1-(1-methylpyrrol-3-yl)methanesulfonamide;N-[5-(7-chloro-1H-indazol-5-yl)-3-cyano-6-(1-methylpyrazol-3-yl)pyrazin-2-yl]-2-(oxan-4-yl)ethanesulfonamide;N-[5-(7-chloro-1H-indazol-5-yl)-3-cyano-6-(1-methylpyrazol-3-yl)pyrazin-2-yl]-2-pyridin-3-ylethanesulfonamide;N-[5-(7-chloro-1H-indazol-5-yl)-3-cyano-6-(1-methylpyrazol-3-yl)pyrazin-2-yl]-1-pyrimidin-5-ylmethanesulfonamide.

Molecular Properties

• Compound Name: N-[5-(7-chloro-1H-indazol-5-yl)-3-cyano-6-(1-methylpyrazol-3-yl)pyrazin-2-yl]-2-cyclopentylethanesulfonamide;N-[5-(7-chloro-1H-indazol-5-yl)-3-cyano-6-(1-methylpyrazol-3-yl)pyrazin-2-yl]-1-(1-methylpyrrol-3-yl)methanesulfonamide;N-[5-(7-chloro-1H-indazol-5-yl)-3-cyano-6-(1-methylpyrazol-3-yl)pyrazin-2-yl]-2-(oxan-4-yl)ethanesulfonamide;N-[5-(7-chloro-1H-indazol-5-yl)-3-cyano-6-(1-methylpyrazol-3-yl)pyrazin-2-yl]-2-pyridin-3-ylethanesulfonamide;N-[5-(7-chloro-1H-indazol-5-yl)-3-cyano-6-(1-methylpyrazol-3-yl)pyrazin-2-yl]-1-pyrimidin-5-ylmethanesulfonamide
• PubChem CID: 159593284
• Molecular Formula: C112H97Cl5N44O11S5
• Molecular Weight: 2572.90 g/mol
• Exact Mass: 2568.54
• IUPAC Name: N-[5-(7-chloro-1H-indazol-5-yl)-3-cyano-6-(1-methylpyrazol-3-yl)pyrazin-2-yl]-2-cyclopentylethanesulfonamide;N-[5-(7-chloro-1H-indazol-5-yl)-3-cyano-6-(1-methylpyrazol-3-yl)pyrazin-2-yl]-1-(1-methylpyrrol-3-yl)methanesulfonamide;N-[5-(7-chloro-1H-indazol-5-yl)-3-cyano-6-(1-methylpyrazol-3-yl)pyrazin-2-yl]-2-(oxan-4-yl)ethanesulfonamide;N-[5-(7-chloro-1H-indazol-5-yl)-3-cyano-6-(1-methylpyrazol-3-yl)pyrazin-2-yl]-2-pyridin-3-ylethanesulfonamide;N-[5-(7-chloro-1H-indazol-5-yl)-3-cyano-6-(1-methylpyrazol-3-yl)pyrazin-2-yl]-1-pyrimidin-5-ylmethanesulfonamide
• SMILES: Cn1ccc(-c2nc(NS(=O)(=O)CCC3CCCC3)c(C#N)nc2-c2cc(Cl)c3[nH]ncc3c2)n1.Cn1ccc(-c2nc(NS(=O)(=O)CCC3CCOCC3)c(C#N)nc2-c2cc(Cl)c3[nH]ncc3c2)n1.Cn1ccc(-c2nc(NS(=O)(=O)CCc3cccnc3)c(C#N)nc2-c2cc(Cl)c3[nH]ncc3c2)n1.Cn1ccc(-c2nc(NS(=O)(=O)Cc3cncnc3)c(C#N)nc2-c2cc(Cl)c3[nH]ncc3c2)n1.Cn1ccc(CS(=O)(=O)Nc2nc(-c3ccn(C)n3)c(-c3cc(Cl)c4[nH]ncc4c3)nc2C#N)c1
• InChI: InChI=1S/C23H18ClN9O2S.C23H23ClN8O3S.C23H23ClN8O2S.C22H18ClN9O2S.C21H15ClN10O2S/c1-33-7-4-18(31-33)22-21(15-9-16-13-27-30-20(16)17(24)10-15)28-19(11-25)23(29-22)32-36(34,35)8-5-14-3-2-6-26-12-14;1-32-6-2-18(30-32)22-21(15-10-16-13-26-29-20(16)17(24)11-15)27-19(12-25)23(28-22)31-36(33,34)9-5-14-3-7-35-8-4-14;1-32-8-6-18(30-32)22-21(15-10-16-13-26-29-20(16)17(24)11-15)27-19(12-25)23(28-22)31-35(33,34)9-7-14-4-2-3-5-14;1-31-5-3-13(11-31)12-35(33,34)30-22-18(9-24)26-20(21(27-22)17-4-6-32(2)29-17)14-7-15-10-25-28-19(15)16(23)8-14;1-32-3-2-16(30-32)20-19(13-4-14-9-26-29-18(14)15(22)5-13)27-17(6-23)21(28-20)31-35(33,34)10-12-7-24-11-25-8-12/h2-4,6-7,9-10,12-13H,5,8H2,1H3,(H,27,30)(H,29,32);2,6,10-11,13-14H,3-5,7-9H2,1H3,(H,26,29)(H,28,31);6,8,10-11,13-14H,2-5,7,9H2,1H3,(H,26,29)(H,28,31);3-8,10-11H,12H2,1-2H3,(H,25,28)(H,27,30);2-5,7-9,11H,10H2,1H3,(H,26,29)(H,28,31)
• InChIKey: MKMXZRPZWGIDPU-UHFFFAOYSA-N
• XLogP: 17.00
• TPSA: 764.03 Ų
• H-Bond Donors: 10
• H-Bond Acceptors: 45
• Rotatable Bonds: 33
• Heavy Atoms: 177
• Complexity: —

Lipinski Rule of Five

4 violations

Rule	Value
MW ≤ 500	2572.90
LogP ≤ 5	17.00
H-Bond Donors ≤ 5	10
H-Bond Acceptors ≤ 10	45

Frequently Asked Questions

What is the IUPAC name of N-[5-(7-chloro-1H-indazol-5-yl)-3-cyano-6-(1-methylpyrazol-3-yl)pyrazin-2-yl]-2-cyclopentylethanesulfonamide;N-[5-(7-chloro-1H-indazol-5-yl)-3-cyano-6-(1-methylpyrazol-3-yl)pyrazin-2-yl]-1-(1-methylpyrrol-3-yl)methanesulfonamide;N-[5-(7-chloro-1H-indazol-5-yl)-3-cyano-6-(1-methylpyrazol-3-yl)pyrazin-2-yl]-2-(oxan-4-yl)ethanesulfonamide;N-[5-(7-chloro-1H-indazol-5-yl)-3-cyano-6-(1-methylpyrazol-3-yl)pyrazin-2-yl]-2-pyridin-3-ylethanesulfonamide;N-[5-(7-chloro-1H-indazol-5-yl)-3-cyano-6-(1-methylpyrazol-3-yl)pyrazin-2-yl]-1-pyrimidin-5-ylmethanesulfonamide?

The IUPAC name of N-[5-(7-chloro-1H-indazol-5-yl)-3-cyano-6-(1-methylpyrazol-3-yl)pyrazin-2-yl]-2-cyclopentylethanesulfonamide;N-[5-(7-chloro-1H-indazol-5-yl)-3-cyano-6-(1-methylpyrazol-3-yl)pyrazin-2-yl]-1-(1-methylpyrrol-3-yl)methanesulfonamide;N-[5-(7-chloro-1H-indazol-5-yl)-3-cyano-6-(1-methylpyrazol-3-yl)pyrazin-2-yl]-2-(oxan-4-yl)ethanesulfonamide;N-[5-(7-chloro-1H-indazol-5-yl)-3-cyano-6-(1-methylpyrazol-3-yl)pyrazin-2-yl]-2-pyridin-3-ylethanesulfonamide;N-[5-(7-chloro-1H-indazol-5-yl)-3-cyano-6-(1-methylpyrazol-3-yl)pyrazin-2-yl]-1-pyrimidin-5-ylmethanesulfonamide (CID 159593284) is N-[5-(7-chloro-1H-indazol-5-yl)-3-cyano-6-(1-methylpyrazol-3-yl)pyrazin-2-yl]-2-cyclopentylethanesulfonamide;N-[5-(7-chloro-1H-indazol-5-yl)-3-cyano-6-(1-methylpyrazol-3-yl)pyrazin-2-yl]-1-(1-methylpyrrol-3-yl)methanesulfonamide;N-[5-(7-chloro-1H-indazol-5-yl)-3-cyano-6-(1-methylpyrazol-3-yl)pyrazin-2-yl]-2-(oxan-4-yl)ethanesulfonamide;N-[5-(7-chloro-1H-indazol-5-yl)-3-cyano-6-(1-methylpyrazol-3-yl)pyrazin-2-yl]-2-pyridin-3-ylethanesulfonamide;N-[5-(7-chloro-1H-indazol-5-yl)-3-cyano-6-(1-methylpyrazol-3-yl)pyrazin-2-yl]-1-pyrimidin-5-ylmethanesulfonamide.

What is the SMILES notation for N-[5-(7-chloro-1H-indazol-5-yl)-3-cyano-6-(1-methylpyrazol-3-yl)pyrazin-2-yl]-2-cyclopentylethanesulfonamide;N-[5-(7-chloro-1H-indazol-5-yl)-3-cyano-6-(1-methylpyrazol-3-yl)pyrazin-2-yl]-1-(1-methylpyrrol-3-yl)methanesulfonamide;N-[5-(7-chloro-1H-indazol-5-yl)-3-cyano-6-(1-methylpyrazol-3-yl)pyrazin-2-yl]-2-(oxan-4-yl)ethanesulfonamide;N-[5-(7-chloro-1H-indazol-5-yl)-3-cyano-6-(1-methylpyrazol-3-yl)pyrazin-2-yl]-2-pyridin-3-ylethanesulfonamide;N-[5-(7-chloro-1H-indazol-5-yl)-3-cyano-6-(1-methylpyrazol-3-yl)pyrazin-2-yl]-1-pyrimidin-5-ylmethanesulfonamide?

The canonical SMILES for N-[5-(7-chloro-1H-indazol-5-yl)-3-cyano-6-(1-methylpyrazol-3-yl)pyrazin-2-yl]-2-cyclopentylethanesulfonamide;N-[5-(7-chloro-1H-indazol-5-yl)-3-cyano-6-(1-methylpyrazol-3-yl)pyrazin-2-yl]-1-(1-methylpyrrol-3-yl)methanesulfonamide;N-[5-(7-chloro-1H-indazol-5-yl)-3-cyano-6-(1-methylpyrazol-3-yl)pyrazin-2-yl]-2-(oxan-4-yl)ethanesulfonamide;N-[5-(7-chloro-1H-indazol-5-yl)-3-cyano-6-(1-methylpyrazol-3-yl)pyrazin-2-yl]-2-pyridin-3-ylethanesulfonamide;N-[5-(7-chloro-1H-indazol-5-yl)-3-cyano-6-(1-methylpyrazol-3-yl)pyrazin-2-yl]-1-pyrimidin-5-ylmethanesulfonamide is Cn1ccc(-c2nc(NS(=O)(=O)CCC3CCCC3)c(C#N)nc2-c2cc(Cl)c3[nH]ncc3c2)n1.Cn1ccc(-c2nc(NS(=O)(=O)CCC3CCOCC3)c(C#N)nc2-c2cc(Cl)c3[nH]ncc3c2)n1.Cn1ccc(-c2nc(NS(=O)(=O)CCc3cccnc3)c(C#N)nc2-c2cc(Cl)c3[nH]ncc3c2)n1.Cn1ccc(-c2nc(NS(=O)(=O)Cc3cncnc3)c(C#N)nc2-c2cc(Cl)c3[nH]ncc3c2)n1.Cn1ccc(CS(=O)(=O)Nc2nc(-c3ccn(C)n3)c(-c3cc(Cl)c4[nH]ncc4c3)nc2C#N)c1.

What is the InChIKey of N-[5-(7-chloro-1H-indazol-5-yl)-3-cyano-6-(1-methylpyrazol-3-yl)pyrazin-2-yl]-2-cyclopentylethanesulfonamide;N-[5-(7-chloro-1H-indazol-5-yl)-3-cyano-6-(1-methylpyrazol-3-yl)pyrazin-2-yl]-1-(1-methylpyrrol-3-yl)methanesulfonamide;N-[5-(7-chloro-1H-indazol-5-yl)-3-cyano-6-(1-methylpyrazol-3-yl)pyrazin-2-yl]-2-(oxan-4-yl)ethanesulfonamide;N-[5-(7-chloro-1H-indazol-5-yl)-3-cyano-6-(1-methylpyrazol-3-yl)pyrazin-2-yl]-2-pyridin-3-ylethanesulfonamide;N-[5-(7-chloro-1H-indazol-5-yl)-3-cyano-6-(1-methylpyrazol-3-yl)pyrazin-2-yl]-1-pyrimidin-5-ylmethanesulfonamide?

The InChIKey is MKMXZRPZWGIDPU-UHFFFAOYSA-N. The full InChI is InChI=1S/C23H18ClN9O2S.C23H23ClN8O3S.C23H23ClN8O2S.C22H18ClN9O2S.C21H15ClN10O2S/c1-33-7-4-18(31-33)22-21(15-9-16-13-27-30-20(16)17(24)10-15)28-19(11-25)23(29-22)32-36(34,35)8-5-14-3-2-6-26-12-14;1-32-6-2-18(30-32)22-21(15-10-16-13-26-29-20(16)17(24)11-15)27-19(12-25)23(28-22)31-36(33,34)9-5-14-3-7-35-8-4-14;1-32-8-6-18(30-32)22-21(15-10-16-13-26-29-20(16)17(24)11-15)27-19(12-25)23(28-22)31-35(33,34)9-7-14-4-2-3-5-14;1-31-5-3-13(11-31)12-35(33,34)30-22-18(9-24)26-20(21(27-22)17-4-6-32(2)29-17)14-7-15-10-25-28-19(15)16(23)8-14;1-32-3-2-16(30-32)20-19(13-4-14-9-26-29-18(14)15(22)5-13)27-17(6-23)21(28-20)31-35(33,34)10-12-7-24-11-25-8-12/h2-4,6-7,9-10,12-13H,5,8H2,1H3,(H,27,30)(H,29,32);2,6,10-11,13-14H,3-5,7-9H2,1H3,(H,26,29)(H,28,31);6,8,10-11,13-14H,2-5,7,9H2,1H3,(H,26,29)(H,28,31);3-8,10-11H,12H2,1-2H3,(H,25,28)(H,27,30);2-5,7-9,11H,10H2,1H3,(H,26,29)(H,28,31).

What are the key properties of N-[5-(7-chloro-1H-indazol-5-yl)-3-cyano-6-(1-methylpyrazol-3-yl)pyrazin-2-yl]-2-cyclopentylethanesulfonamide;N-[5-(7-chloro-1H-indazol-5-yl)-3-cyano-6-(1-methylpyrazol-3-yl)pyrazin-2-yl]-1-(1-methylpyrrol-3-yl)methanesulfonamide;N-[5-(7-chloro-1H-indazol-5-yl)-3-cyano-6-(1-methylpyrazol-3-yl)pyrazin-2-yl]-2-(oxan-4-yl)ethanesulfonamide;N-[5-(7-chloro-1H-indazol-5-yl)-3-cyano-6-(1-methylpyrazol-3-yl)pyrazin-2-yl]-2-pyridin-3-ylethanesulfonamide;N-[5-(7-chloro-1H-indazol-5-yl)-3-cyano-6-(1-methylpyrazol-3-yl)pyrazin-2-yl]-1-pyrimidin-5-ylmethanesulfonamide?

N-[5-(7-chloro-1H-indazol-5-yl)-3-cyano-6-(1-methylpyrazol-3-yl)pyrazin-2-yl]-2-cyclopentylethanesulfonamide;N-[5-(7-chloro-1H-indazol-5-yl)-3-cyano-6-(1-methylpyrazol-3-yl)pyrazin-2-yl]-1-(1-methylpyrrol-3-yl)methanesulfonamide;N-[5-(7-chloro-1H-indazol-5-yl)-3-cyano-6-(1-methylpyrazol-3-yl)pyrazin-2-yl]-2-(oxan-4-yl)ethanesulfonamide;N-[5-(7-chloro-1H-indazol-5-yl)-3-cyano-6-(1-methylpyrazol-3-yl)pyrazin-2-yl]-2-pyridin-3-ylethanesulfonamide;N-[5-(7-chloro-1H-indazol-5-yl)-3-cyano-6-(1-methylpyrazol-3-yl)pyrazin-2-yl]-1-pyrimidin-5-ylmethanesulfonamide has a molecular weight of 2572.90 g/mol, XLogP of 17.00, 33 rotatable bonds, 10 hydrogen bond donors, and 45 hydrogen bond acceptors.

Where does this data come from?

All data for N-[5-(7-chloro-1H-indazol-5-yl)-3-cyano-6-(1-methylpyrazol-3-yl)pyrazin-2-yl]-2-cyclopentylethanesulfonamide;N-[5-(7-chloro-1H-indazol-5-yl)-3-cyano-6-(1-methylpyrazol-3-yl)pyrazin-2-yl]-1-(1-methylpyrrol-3-yl)methanesulfonamide;N-[5-(7-chloro-1H-indazol-5-yl)-3-cyano-6-(1-methylpyrazol-3-yl)pyrazin-2-yl]-2-(oxan-4-yl)ethanesulfonamide;N-[5-(7-chloro-1H-indazol-5-yl)-3-cyano-6-(1-methylpyrazol-3-yl)pyrazin-2-yl]-2-pyridin-3-ylethanesulfonamide;N-[5-(7-chloro-1H-indazol-5-yl)-3-cyano-6-(1-methylpyrazol-3-yl)pyrazin-2-yl]-1-pyrimidin-5-ylmethanesulfonamide is sourced from PubChem (CID 159593284), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).