N-[2-[3-cyano-4-[(4R)-3,3-difluoro-1-(2-hydroxyacetyl)piperidin-4-yl]oxyphenyl]-4-pyridinyl]cyclopropanecarboxamide;N-[2-[3-cyano-4-[(3R,4R)-3-fluoro-1-(2-hydroxyacetyl)piperidin-4-yl]oxyphenyl]-4-pyridinyl]cyclopropanecarboxamide;N-[2-[3-cyano-4-[(2S,4S)-1-(2-hydroxyacetyl)-2-methylpiperidin-4-yl]oxyphenyl]-4-pyridinyl]cyclopropanecarboxamide;trans-(1R,2R)-N-[2-[3-cyano-4-[(4S)-3,3-difluoro-1-(2-hydroxyacetyl)piperidin-4-yl]oxyphenyl]-4-pyridinyl]-2-(6-methoxy-3-pyridinyl)cyclopropane-1-carboxamide

C99H98F5N17O17 — CID 159596912

IUPACN-[2-[3-cyano-4-[(4R)-3,3-difluoro-1-(2-hydroxyacetyl)piperidin-4-yl]oxyphenyl]-4-pyridinyl]cyclopropanecarboxamide;N-[2-[3-cyano-4-[(3R,4R)-3-fluoro-1-(2-hydroxyacetyl)piperidin-4-yl]oxyphenyl]-4-pyridinyl]cyclopropanecarboxamide;N-[2-[3-cyano-4-[(2S,4S)-1-(2-hydroxyacetyl)-2-methylpiperidin-4-yl]oxyphenyl]-4-pyridinyl]cyclopropanecarboxamide;trans-(1R,2R)-N-[2-[3-cyano-4-[(4S)-3,3-difluoro-1-(2-hydroxyacetyl)piperidin-4-yl]oxyphenyl]-4-pyridinyl]-2-(6-methoxy-3-pyridinyl)cyclopropane-1-carboxamide
SMILESCOc1ccc([C@@H]2C[C@H]2C(=O)Nc2ccnc(-c3ccc(O[C@H]4CCN(C(=O)CO)CC4(F)F)c(C#N)c3)c2)cn1.C[C@H]1C[C@@H](Oc2ccc(-c3cc(NC(=O)C4CC4)ccn3)cc2C#N)CCN1C(=O)CO.N#Cc1cc(-c2cc(NC(=O)C3CC3)ccn2)ccc1O[C@@H]1CCN(C(=O)CO)CC1(F)F.N#Cc1cc(-c2cc(NC(=O)C3CC3)ccn2)ccc1O[C@@H]1CCN(C(=O)CO)C[C@H]1F
InChIInChI=1S/C29H27F2N5O5.C24H26N4O4.C23H22F2N4O4.C23H23FN4O4/c1-40-26-5-3-18(14-34-26)21-12-22(21)28(39)35-20-6-8-33-23(11-20)17-2-4-24(19(10-17)13-32)41-25-7-9-36(27(38)15-37)16-29(25,30)31;1-15-10-20(7-9-28(15)23(30)14-29)32-22-5-4-17(11-18(22)13-25)21-12-19(6-8-26-21)27-24(31)16-2-3-16;24-23(25)13-29(21(31)12-30)8-6-20(23)33-19-4-3-15(9-16(19)11-26)18-10-17(5-7-27-18)28-22(32)14-1-2-14;24-18-12-28(22(30)13-29)8-6-21(18)32-20-4-3-15(9-16(20)11-25)19-10-17(5-7-26-19)27-23(31)14-1-2-14/h2-6,8,10-11,14,21-22,25,37H,7,9,12,15-16H2,1H3,(H,33,35,39);4-6,8,11-12,15-16,20,29H,2-3,7,9-10,14H2,1H3,(H,26,27,31);3-5,7,9-10,14,20,30H,1-2,6,8,12-13H2,(H,27,28,32);3-5,7,9-10,14,18,21,29H,1-2,6,8,12-13H2,(H,26,27,31)/t21-,22+,25-;15-,20-;20-;18-,21-/m0011/s1
InChIKeyMKYUUVBSTQRWLR-OSYBZOBVSA-N
MW1892.96 g/mol
LogP10.95
Rot. Bonds26

About N-[2-[3-cyano-4-[(4R)-3,3-difluoro-1-(2-hydroxyacetyl)piperidin-4-yl]oxyphenyl]-4-pyridinyl]cyclopropanecarboxamide;N-[2-[3-cyano-4-[(3R,4R)-3-fluoro-1-(2-hydroxyacetyl)piperidin-4-yl]oxyphenyl]-4-pyridinyl]cyclopropanecarboxamide;N-[2-[3-cyano-4-[(2S,4S)-1-(2-hydroxyacetyl)-2-methylpiperidin-4-yl]oxyphenyl]-4-pyridinyl]cyclopropanecarboxamide;trans-(1R,2R)-N-[2-[3-cyano-4-[(4S)-3,3-difluoro-1-(2-hydroxyacetyl)piperidin-4-yl]oxyphenyl]-4-pyridinyl]-2-(6-methoxy-3-pyridinyl)cyclopropane-1-carboxamide

N-[2-[3-cyano-4-[(4R)-3,3-difluoro-1-(2-hydroxyacetyl)piperidin-4-yl]oxyphenyl]-4-pyridinyl]cyclopropanecarboxamide;N-[2-[3-cyano-4-[(3R,4R)-3-fluoro-1-(2-hydroxyacetyl)piperidin-4-yl]oxyphenyl]-4-pyridinyl]cyclopropanecarboxamide;N-[2-[3-cyano-4-[(2S,4S)-1-(2-hydroxyacetyl)-2-methylpiperidin-4-yl]oxyphenyl]-4-pyridinyl]cyclopropanecarboxamide;trans-(1R,2R)-N-[2-[3-cyano-4-[(4S)-3,3-difluoro-1-(2-hydroxyacetyl)piperidin-4-yl]oxyphenyl]-4-pyridinyl]-2-(6-methoxy-3-pyridinyl)cyclopropane-1-carboxamide (PubChem CID 159596912) has the molecular formula C99H98F5N17O17 and a molecular weight of 1892.96 g/mol. Its IUPAC name is N-[2-[3-cyano-4-[(4R)-3,3-difluoro-1-(2-hydroxyacetyl)piperidin-4-yl]oxyphenyl]-4-pyridinyl]cyclopropanecarboxamide;N-[2-[3-cyano-4-[(3R,4R)-3-fluoro-1-(2-hydroxyacetyl)piperidin-4-yl]oxyphenyl]-4-pyridinyl]cyclopropanecarboxamide;N-[2-[3-cyano-4-[(2S,4S)-1-(2-hydroxyacetyl)-2-methylpiperidin-4-yl]oxyphenyl]-4-pyridinyl]cyclopropanecarboxamide;trans-(1R,2R)-N-[2-[3-cyano-4-[(4S)-3,3-difluoro-1-(2-hydroxyacetyl)piperidin-4-yl]oxyphenyl]-4-pyridinyl]-2-(6-methoxy-3-pyridinyl)cyclopropane-1-carboxamide.

Molecular Properties

Compound NameN-[2-[3-cyano-4-[(4R)-3,3-difluoro-1-(2-hydroxyacetyl)piperidin-4-yl]oxyphenyl]-4-pyridinyl]cyclopropanecarboxamide;N-[2-[3-cyano-4-[(3R,4R)-3-fluoro-1-(2-hydroxyacetyl)piperidin-4-yl]oxyphenyl]-4-pyridinyl]cyclopropanecarboxamide;N-[2-[3-cyano-4-[(2S,4S)-1-(2-hydroxyacetyl)-2-methylpiperidin-4-yl]oxyphenyl]-4-pyridinyl]cyclopropanecarboxamide;trans-(1R,2R)-N-[2-[3-cyano-4-[(4S)-3,3-difluoro-1-(2-hydroxyacetyl)piperidin-4-yl]oxyphenyl]-4-pyridinyl]-2-(6-methoxy-3-pyridinyl)cyclopropane-1-carboxamide
PubChem CID159596912
Molecular FormulaC99H98F5N17O17
Molecular Weight1892.96 g/mol
Exact Mass1891.72
IUPAC NameN-[2-[3-cyano-4-[(4R)-3,3-difluoro-1-(2-hydroxyacetyl)piperidin-4-yl]oxyphenyl]-4-pyridinyl]cyclopropanecarboxamide;N-[2-[3-cyano-4-[(3R,4R)-3-fluoro-1-(2-hydroxyacetyl)piperidin-4-yl]oxyphenyl]-4-pyridinyl]cyclopropanecarboxamide;N-[2-[3-cyano-4-[(2S,4S)-1-(2-hydroxyacetyl)-2-methylpiperidin-4-yl]oxyphenyl]-4-pyridinyl]cyclopropanecarboxamide;trans-(1R,2R)-N-[2-[3-cyano-4-[(4S)-3,3-difluoro-1-(2-hydroxyacetyl)piperidin-4-yl]oxyphenyl]-4-pyridinyl]-2-(6-methoxy-3-pyridinyl)cyclopropane-1-carboxamide
SMILESCOc1ccc([C@@H]2C[C@H]2C(=O)Nc2ccnc(-c3ccc(O[C@H]4CCN(C(=O)CO)CC4(F)F)c(C#N)c3)c2)cn1.C[C@H]1C[C@@H](Oc2ccc(-c3cc(NC(=O)C4CC4)ccn3)cc2C#N)CCN1C(=O)CO.N#Cc1cc(-c2cc(NC(=O)C3CC3)ccn2)ccc1O[C@@H]1CCN(C(=O)CO)CC1(F)F.N#Cc1cc(-c2cc(NC(=O)C3CC3)ccn2)ccc1O[C@@H]1CCN(C(=O)CO)C[C@H]1F
InChIInChI=1S/C29H27F2N5O5.C24H26N4O4.C23H22F2N4O4.C23H23FN4O4/c1-40-26-5-3-18(14-34-26)21-12-22(21)28(39)35-20-6-8-33-23(11-20)17-2-4-24(19(10-17)13-32)41-25-7-9-36(27(38)15-37)16-29(25,30)31;1-15-10-20(7-9-28(15)23(30)14-29)32-22-5-4-17(11-18(22)13-25)21-12-19(6-8-26-21)27-24(31)16-2-3-16;24-23(25)13-29(21(31)12-30)8-6-20(23)33-19-4-3-15(9-16(19)11-26)18-10-17(5-7-27-18)28-22(32)14-1-2-14;24-18-12-28(22(30)13-29)8-6-21(18)32-20-4-3-15(9-16(20)11-25)19-10-17(5-7-26-19)27-23(31)14-1-2-14/h2-6,8,10-11,14,21-22,25,37H,7,9,12,15-16H2,1H3,(H,33,35,39);4-6,8,11-12,15-16,20,29H,2-3,7,9-10,14H2,1H3,(H,26,27,31);3-5,7,9-10,14,20,30H,1-2,6,8,12-13H2,(H,27,28,32);3-5,7,9-10,14,18,21,29H,1-2,6,8,12-13H2,(H,26,27,31)/t21-,22+,25-;15-,20-;20-;18-,21-/m0011/s1
InChIKeyMKYUUVBSTQRWLR-OSYBZOBVSA-N
XLogP10.95
TPSA484.32 Ų
H-Bond Donors8
H-Bond Acceptors26
Rotatable Bonds26
Heavy Atoms138
Complexity—

Lipinski Rule of Five

4 violations

RuleValue
MW ≤ 5001892.96
LogP ≤ 510.95
H-Bond Donors ≤ 58
H-Bond Acceptors ≤ 1026

Analyze N-[2-[3-cyano-4-[(4R)-3,3-difluoro-1-(2-hydroxyacetyl)piperidin-4-yl]oxyphenyl]-4-pyridinyl]cyclopropanecarboxamide;N-[2-[3-cyano-4-[(3R,4R)-3-fluoro-1-(2-hydroxyacetyl)piperidin-4-yl]oxyphenyl]-4-pyridinyl]cyclopropanecarboxamide;N-[2-[3-cyano-4-[(2S,4S)-1-(2-hydroxyacetyl)-2-methylpiperidin-4-yl]oxyphenyl]-4-pyridinyl]cyclopropanecarboxamide;trans-(1R,2R)-N-[2-[3-cyano-4-[(4S)-3,3-difluoro-1-(2-hydroxyacetyl)piperidin-4-yl]oxyphenyl]-4-pyridinyl]-2-(6-methoxy-3-pyridinyl)cyclopropane-1-carboxamide with MolForge

Explore ADMET properties, 3D molecular structure, drug-likeness score, and discover similar compounds using our AI-powered platform.

Launch Full Analysis

Related Compounds

N-[2-[3-cyano-4-[3,3-difluoro-1-(2-hydroxyacetyl)piperidin-4-yl]oxyphenyl]-4-pyridinyl]cyclopropanecarboxamide
CID 129256300
trans-(1R,2R)-N-[2-[3-cyano-4-[(4S)-3,3-difluoro-1-(2-hydroxyacetyl)piperidin-4-yl]oxyphenyl]-4-pyridinyl]-2-(6-methoxy-3-pyridinyl)cyclopropane-1-carboxamide
CID 129256302
N-[2-[3-cyano-4-[(3R,4R)-3-fluoro-1-(2-hydroxyacetyl)piperidin-4-yl]oxyphenyl]-4-pyridinyl]cyclopropanecarboxamide
CID 129256304
trans-(1R,2R)-N-[3-[3-cyano-4-[(4S)-3,3-difluoro-1-(2-hydroxyacetyl)piperidin-4-yl]oxyphenyl]phenyl]-2-(6-cyclopropyl-3-pyridinyl)cyclopropane-1-carboxamide
CID 129256306
trans-(1R,2R)-N-[3-[3-cyano-4-[(3R,4S)-3-fluoro-1-(2-hydroxyacetyl)piperidin-4-yl]oxyphenyl]phenyl]-2-pyridin-3-ylcyclopropane-1-carboxamide
CID 129256319
trans-(1R,2R)-N-[2-[3-cyano-4-[(4S)-3,3-difluoro-1-(2-hydroxyacetyl)piperidin-4-yl]oxyphenyl]-4-pyridinyl]-2-(1-methylpyrazol-4-yl)cyclopropane-1-carboxamide
CID 129256320
trans-(1R,2R)-N-[2-[3-cyano-4-[(4S)-3,3-difluoro-1-(2-hydroxyacetyl)piperidin-4-yl]oxyphenyl]-4-pyridinyl]-2-pyridin-3-ylcyclopropane-1-carboxamide
CID 129256323
trans-(1R,2R)-N-[3-[3-cyano-4-[(4S)-3,3-difluoro-1-(2-hydroxyacetyl)piperidin-4-yl]oxyphenyl]phenyl]-2-pyridin-3-ylcyclopropane-1-carboxamide
CID 129256324
(2S)-N-[2-[3-cyano-4-[(4S)-3,3-difluoro-1-(2-hydroxyacetyl)piperidin-4-yl]oxyphenyl]-4-pyridinyl]-2-(1-methylpyrazol-4-yl)cyclopropane-1-carboxamide
CID 129256325
trans-(1S,2S)-N-[3-[3-cyano-4-[(4S)-3,3-difluoro-1-(2-hydroxyacetyl)piperidin-4-yl]oxyphenyl]phenyl]-2-pyridin-3-ylcyclopropane-1-carboxamide
CID 129256327
trans-(1R,2R)-N-[2-[3-cyano-4-[(4S)-1-[(2S)-2,3-dihydroxypropanoyl]-3,3-difluoropiperidin-4-yl]oxyphenyl]-4-pyridinyl]-2-pyridin-3-ylcyclopropane-1-carboxamide
CID 129256328
trans-(1R,2R)-N-[2-[3-cyano-4-[(3R,4S)-3-fluoro-1-(2-hydroxyacetyl)piperidin-4-yl]oxyphenyl]-4-pyridinyl]-2-pyridin-3-ylcyclopropane-1-carboxamide
CID 129256332

Frequently Asked Questions

What is the IUPAC name of N-[2-[3-cyano-4-[(4R)-3,3-difluoro-1-(2-hydroxyacetyl)piperidin-4-yl]oxyphenyl]-4-pyridinyl]cyclopropanecarboxamide;N-[2-[3-cyano-4-[(3R,4R)-3-fluoro-1-(2-hydroxyacetyl)piperidin-4-yl]oxyphenyl]-4-pyridinyl]cyclopropanecarboxamide;N-[2-[3-cyano-4-[(2S,4S)-1-(2-hydroxyacetyl)-2-methylpiperidin-4-yl]oxyphenyl]-4-pyridinyl]cyclopropanecarboxamide;trans-(1R,2R)-N-[2-[3-cyano-4-[(4S)-3,3-difluoro-1-(2-hydroxyacetyl)piperidin-4-yl]oxyphenyl]-4-pyridinyl]-2-(6-methoxy-3-pyridinyl)cyclopropane-1-carboxamide?
The IUPAC name of N-[2-[3-cyano-4-[(4R)-3,3-difluoro-1-(2-hydroxyacetyl)piperidin-4-yl]oxyphenyl]-4-pyridinyl]cyclopropanecarboxamide;N-[2-[3-cyano-4-[(3R,4R)-3-fluoro-1-(2-hydroxyacetyl)piperidin-4-yl]oxyphenyl]-4-pyridinyl]cyclopropanecarboxamide;N-[2-[3-cyano-4-[(2S,4S)-1-(2-hydroxyacetyl)-2-methylpiperidin-4-yl]oxyphenyl]-4-pyridinyl]cyclopropanecarboxamide;trans-(1R,2R)-N-[2-[3-cyano-4-[(4S)-3,3-difluoro-1-(2-hydroxyacetyl)piperidin-4-yl]oxyphenyl]-4-pyridinyl]-2-(6-methoxy-3-pyridinyl)cyclopropane-1-carboxamide (CID 159596912) is N-[2-[3-cyano-4-[(4R)-3,3-difluoro-1-(2-hydroxyacetyl)piperidin-4-yl]oxyphenyl]-4-pyridinyl]cyclopropanecarboxamide;N-[2-[3-cyano-4-[(3R,4R)-3-fluoro-1-(2-hydroxyacetyl)piperidin-4-yl]oxyphenyl]-4-pyridinyl]cyclopropanecarboxamide;N-[2-[3-cyano-4-[(2S,4S)-1-(2-hydroxyacetyl)-2-methylpiperidin-4-yl]oxyphenyl]-4-pyridinyl]cyclopropanecarboxamide;trans-(1R,2R)-N-[2-[3-cyano-4-[(4S)-3,3-difluoro-1-(2-hydroxyacetyl)piperidin-4-yl]oxyphenyl]-4-pyridinyl]-2-(6-methoxy-3-pyridinyl)cyclopropane-1-carboxamide.
What is the SMILES notation for N-[2-[3-cyano-4-[(4R)-3,3-difluoro-1-(2-hydroxyacetyl)piperidin-4-yl]oxyphenyl]-4-pyridinyl]cyclopropanecarboxamide;N-[2-[3-cyano-4-[(3R,4R)-3-fluoro-1-(2-hydroxyacetyl)piperidin-4-yl]oxyphenyl]-4-pyridinyl]cyclopropanecarboxamide;N-[2-[3-cyano-4-[(2S,4S)-1-(2-hydroxyacetyl)-2-methylpiperidin-4-yl]oxyphenyl]-4-pyridinyl]cyclopropanecarboxamide;trans-(1R,2R)-N-[2-[3-cyano-4-[(4S)-3,3-difluoro-1-(2-hydroxyacetyl)piperidin-4-yl]oxyphenyl]-4-pyridinyl]-2-(6-methoxy-3-pyridinyl)cyclopropane-1-carboxamide?
The canonical SMILES for N-[2-[3-cyano-4-[(4R)-3,3-difluoro-1-(2-hydroxyacetyl)piperidin-4-yl]oxyphenyl]-4-pyridinyl]cyclopropanecarboxamide;N-[2-[3-cyano-4-[(3R,4R)-3-fluoro-1-(2-hydroxyacetyl)piperidin-4-yl]oxyphenyl]-4-pyridinyl]cyclopropanecarboxamide;N-[2-[3-cyano-4-[(2S,4S)-1-(2-hydroxyacetyl)-2-methylpiperidin-4-yl]oxyphenyl]-4-pyridinyl]cyclopropanecarboxamide;trans-(1R,2R)-N-[2-[3-cyano-4-[(4S)-3,3-difluoro-1-(2-hydroxyacetyl)piperidin-4-yl]oxyphenyl]-4-pyridinyl]-2-(6-methoxy-3-pyridinyl)cyclopropane-1-carboxamide is COc1ccc([C@@H]2C[C@H]2C(=O)Nc2ccnc(-c3ccc(O[C@H]4CCN(C(=O)CO)CC4(F)F)c(C#N)c3)c2)cn1.C[C@H]1C[C@@H](Oc2ccc(-c3cc(NC(=O)C4CC4)ccn3)cc2C#N)CCN1C(=O)CO.N#Cc1cc(-c2cc(NC(=O)C3CC3)ccn2)ccc1O[C@@H]1CCN(C(=O)CO)CC1(F)F.N#Cc1cc(-c2cc(NC(=O)C3CC3)ccn2)ccc1O[C@@H]1CCN(C(=O)CO)C[C@H]1F.
What is the InChIKey of N-[2-[3-cyano-4-[(4R)-3,3-difluoro-1-(2-hydroxyacetyl)piperidin-4-yl]oxyphenyl]-4-pyridinyl]cyclopropanecarboxamide;N-[2-[3-cyano-4-[(3R,4R)-3-fluoro-1-(2-hydroxyacetyl)piperidin-4-yl]oxyphenyl]-4-pyridinyl]cyclopropanecarboxamide;N-[2-[3-cyano-4-[(2S,4S)-1-(2-hydroxyacetyl)-2-methylpiperidin-4-yl]oxyphenyl]-4-pyridinyl]cyclopropanecarboxamide;trans-(1R,2R)-N-[2-[3-cyano-4-[(4S)-3,3-difluoro-1-(2-hydroxyacetyl)piperidin-4-yl]oxyphenyl]-4-pyridinyl]-2-(6-methoxy-3-pyridinyl)cyclopropane-1-carboxamide?
The InChIKey is MKYUUVBSTQRWLR-OSYBZOBVSA-N. The full InChI is InChI=1S/C29H27F2N5O5.C24H26N4O4.C23H22F2N4O4.C23H23FN4O4/c1-40-26-5-3-18(14-34-26)21-12-22(21)28(39)35-20-6-8-33-23(11-20)17-2-4-24(19(10-17)13-32)41-25-7-9-36(27(38)15-37)16-29(25,30)31;1-15-10-20(7-9-28(15)23(30)14-29)32-22-5-4-17(11-18(22)13-25)21-12-19(6-8-26-21)27-24(31)16-2-3-16;24-23(25)13-29(21(31)12-30)8-6-20(23)33-19-4-3-15(9-16(19)11-26)18-10-17(5-7-27-18)28-22(32)14-1-2-14;24-18-12-28(22(30)13-29)8-6-21(18)32-20-4-3-15(9-16(20)11-25)19-10-17(5-7-26-19)27-23(31)14-1-2-14/h2-6,8,10-11,14,21-22,25,37H,7,9,12,15-16H2,1H3,(H,33,35,39);4-6,8,11-12,15-16,20,29H,2-3,7,9-10,14H2,1H3,(H,26,27,31);3-5,7,9-10,14,20,30H,1-2,6,8,12-13H2,(H,27,28,32);3-5,7,9-10,14,18,21,29H,1-2,6,8,12-13H2,(H,26,27,31)/t21-,22+,25-;15-,20-;20-;18-,21-/m0011/s1.
What are the key properties of N-[2-[3-cyano-4-[(4R)-3,3-difluoro-1-(2-hydroxyacetyl)piperidin-4-yl]oxyphenyl]-4-pyridinyl]cyclopropanecarboxamide;N-[2-[3-cyano-4-[(3R,4R)-3-fluoro-1-(2-hydroxyacetyl)piperidin-4-yl]oxyphenyl]-4-pyridinyl]cyclopropanecarboxamide;N-[2-[3-cyano-4-[(2S,4S)-1-(2-hydroxyacetyl)-2-methylpiperidin-4-yl]oxyphenyl]-4-pyridinyl]cyclopropanecarboxamide;trans-(1R,2R)-N-[2-[3-cyano-4-[(4S)-3,3-difluoro-1-(2-hydroxyacetyl)piperidin-4-yl]oxyphenyl]-4-pyridinyl]-2-(6-methoxy-3-pyridinyl)cyclopropane-1-carboxamide?
N-[2-[3-cyano-4-[(4R)-3,3-difluoro-1-(2-hydroxyacetyl)piperidin-4-yl]oxyphenyl]-4-pyridinyl]cyclopropanecarboxamide;N-[2-[3-cyano-4-[(3R,4R)-3-fluoro-1-(2-hydroxyacetyl)piperidin-4-yl]oxyphenyl]-4-pyridinyl]cyclopropanecarboxamide;N-[2-[3-cyano-4-[(2S,4S)-1-(2-hydroxyacetyl)-2-methylpiperidin-4-yl]oxyphenyl]-4-pyridinyl]cyclopropanecarboxamide;trans-(1R,2R)-N-[2-[3-cyano-4-[(4S)-3,3-difluoro-1-(2-hydroxyacetyl)piperidin-4-yl]oxyphenyl]-4-pyridinyl]-2-(6-methoxy-3-pyridinyl)cyclopropane-1-carboxamide has a molecular weight of 1892.96 g/mol, XLogP of 10.95, 26 rotatable bonds, 8 hydrogen bond donors, and 26 hydrogen bond acceptors.
Where does this data come from?
All data for N-[2-[3-cyano-4-[(4R)-3,3-difluoro-1-(2-hydroxyacetyl)piperidin-4-yl]oxyphenyl]-4-pyridinyl]cyclopropanecarboxamide;N-[2-[3-cyano-4-[(3R,4R)-3-fluoro-1-(2-hydroxyacetyl)piperidin-4-yl]oxyphenyl]-4-pyridinyl]cyclopropanecarboxamide;N-[2-[3-cyano-4-[(2S,4S)-1-(2-hydroxyacetyl)-2-methylpiperidin-4-yl]oxyphenyl]-4-pyridinyl]cyclopropanecarboxamide;trans-(1R,2R)-N-[2-[3-cyano-4-[(4S)-3,3-difluoro-1-(2-hydroxyacetyl)piperidin-4-yl]oxyphenyl]-4-pyridinyl]-2-(6-methoxy-3-pyridinyl)cyclopropane-1-carboxamide is sourced from PubChem (CID 159596912), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).