(5S,6S)-2-amino-5-[4-(1,1-difluoroethyl)phenyl]-3,6-dimethyl-6-[3-(trifluoromethyl)phenyl]-5H-pyrimidin-4-one;(5R,6S)-2-amino-5-[4-(1,1-difluoroethyl)phenyl]-3,6-dimethyl-6-[3-(trifluoromethyl)phenyl]-5H-pyrimidin-4-one;3-[3-[(4S,5S)-2-amino-1,4-dimethyl-6-oxo-5-prop-2-ynyl-5H-pyrimidin-4-yl]phenyl]benzonitrile;3-[3-[(4S,5R)-2-amino-1,4-dimethyl-6-oxo-5-prop-2-ynyl-5H-pyrimidin-4-yl]phenyl]benzonitrile;3-[3-[(4S)-2-amino-1,4-dimethyl-6-oxo-5H-pyrimidin-4-yl]piperidin-1-yl]sulfonylbenzonitrile;(6S)-2-amino-3,6-dimethyl-6-(7-pyridin-3-yl-1-benzothiophen-3-yl)-5H-pyrimidin-4-one

C123H121F10N23O8S2 — CID 159598404

IUPAC(5S,6S)-2-amino-5-[4-(1,1-difluoroethyl)phenyl]-3,6-dimethyl-6-[3-(trifluoromethyl)phenyl]-5H-pyrimidin-4-one;(5R,6S)-2-amino-5-[4-(1,1-difluoroethyl)phenyl]-3,6-dimethyl-6-[3-(trifluoromethyl)phenyl]-5H-pyrimidin-4-one;3-[3-[(4S,5S)-2-amino-1,4-dimethyl-6-oxo-5-prop-2-ynyl-5H-pyrimidin-4-yl]phenyl]benzonitrile;3-[3-[(4S,5R)-2-amino-1,4-dimethyl-6-oxo-5-prop-2-ynyl-5H-pyrimidin-4-yl]phenyl]benzonitrile;3-[3-[(4S)-2-amino-1,4-dimethyl-6-oxo-5H-pyrimidin-4-yl]piperidin-1-yl]sulfonylbenzonitrile;(6S)-2-amino-3,6-dimethyl-6-(7-pyridin-3-yl-1-benzothiophen-3-yl)-5H-pyrimidin-4-one
SMILESC#CC[C@@H]1C(=O)N(C)C(N)=N[C@]1(C)c1cccc(-c2cccc(C#N)c2)c1.C#CC[C@H]1C(=O)N(C)C(N)=N[C@]1(C)c1cccc(-c2cccc(C#N)c2)c1.CN1C(=O)C[C@@](C)(C2CCCN(S(=O)(=O)c3cccc(C#N)c3)C2)N=C1N.CN1C(=O)C[C@@](C)(c2csc3c(-c4cccnc4)cccc23)N=C1N.CN1C(=O)[C@@H](c2ccc(C(C)(F)F)cc2)[C@@](C)(c2cccc(C(F)(F)F)c2)N=C1N.CN1C(=O)[C@H](c2ccc(C(C)(F)F)cc2)[C@@](C)(c2cccc(C(F)(F)F)c2)N=C1N
InChIInChI=1S/2C22H20N4O.2C21H20F5N3O.C19H18N4OS.C18H23N5O3S/c2*1-4-7-19-20(27)26(3)21(24)25-22(19,2)18-11-6-10-17(13-18)16-9-5-8-15(12-16)14-23;2*1-19(14-5-4-6-15(11-14)21(24,25)26)16(17(30)29(3)18(27)28-19)12-7-9-13(10-8-12)20(2,22)23;1-19(9-16(24)23(2)18(20)22-19)15-11-25-17-13(6-3-7-14(15)17)12-5-4-8-21-10-12;1-18(10-16(24)22(2)17(20)21-18)14-6-4-8-23(12-14)27(25,26)15-7-3-5-13(9-15)11-19/h2*1,5-6,8-13,19H,7H2,2-3H3,(H2,24,25);2*4-11,16H,1-3H3,(H2,27,28);3-8,10-11H,9H2,1-2H3,(H2,20,22);3,5,7,9,14H,4,6,8,10,12H2,1-2H3,(H2,20,21)/t19-,22+;19-,22-;16-,19+;16-,19-;19-;14?,18-/m010100/s1
InChIKeyMLDMIIDWRCMMNS-KDHGKMBRSA-N
MW2303.59 g/mol
LogP19.19
Rot. Bonds17

About (5S,6S)-2-amino-5-[4-(1,1-difluoroethyl)phenyl]-3,6-dimethyl-6-[3-(trifluoromethyl)phenyl]-5H-pyrimidin-4-one;(5R,6S)-2-amino-5-[4-(1,1-difluoroethyl)phenyl]-3,6-dimethyl-6-[3-(trifluoromethyl)phenyl]-5H-pyrimidin-4-one;3-[3-[(4S,5S)-2-amino-1,4-dimethyl-6-oxo-5-prop-2-ynyl-5H-pyrimidin-4-yl]phenyl]benzonitrile;3-[3-[(4S,5R)-2-amino-1,4-dimethyl-6-oxo-5-prop-2-ynyl-5H-pyrimidin-4-yl]phenyl]benzonitrile;3-[3-[(4S)-2-amino-1,4-dimethyl-6-oxo-5H-pyrimidin-4-yl]piperidin-1-yl]sulfonylbenzonitrile;(6S)-2-amino-3,6-dimethyl-6-(7-pyridin-3-yl-1-benzothiophen-3-yl)-5H-pyrimidin-4-one

(5S,6S)-2-amino-5-[4-(1,1-difluoroethyl)phenyl]-3,6-dimethyl-6-[3-(trifluoromethyl)phenyl]-5H-pyrimidin-4-one;(5R,6S)-2-amino-5-[4-(1,1-difluoroethyl)phenyl]-3,6-dimethyl-6-[3-(trifluoromethyl)phenyl]-5H-pyrimidin-4-one;3-[3-[(4S,5S)-2-amino-1,4-dimethyl-6-oxo-5-prop-2-ynyl-5H-pyrimidin-4-yl]phenyl]benzonitrile;3-[3-[(4S,5R)-2-amino-1,4-dimethyl-6-oxo-5-prop-2-ynyl-5H-pyrimidin-4-yl]phenyl]benzonitrile;3-[3-[(4S)-2-amino-1,4-dimethyl-6-oxo-5H-pyrimidin-4-yl]piperidin-1-yl]sulfonylbenzonitrile;(6S)-2-amino-3,6-dimethyl-6-(7-pyridin-3-yl-1-benzothiophen-3-yl)-5H-pyrimidin-4-one (PubChem CID 159598404) has the molecular formula C123H121F10N23O8S2 and a molecular weight of 2303.59 g/mol. Its IUPAC name is (5S,6S)-2-amino-5-[4-(1,1-difluoroethyl)phenyl]-3,6-dimethyl-6-[3-(trifluoromethyl)phenyl]-5H-pyrimidin-4-one;(5R,6S)-2-amino-5-[4-(1,1-difluoroethyl)phenyl]-3,6-dimethyl-6-[3-(trifluoromethyl)phenyl]-5H-pyrimidin-4-one;3-[3-[(4S,5S)-2-amino-1,4-dimethyl-6-oxo-5-prop-2-ynyl-5H-pyrimidin-4-yl]phenyl]benzonitrile;3-[3-[(4S,5R)-2-amino-1,4-dimethyl-6-oxo-5-prop-2-ynyl-5H-pyrimidin-4-yl]phenyl]benzonitrile;3-[3-[(4S)-2-amino-1,4-dimethyl-6-oxo-5H-pyrimidin-4-yl]piperidin-1-yl]sulfonylbenzonitrile;(6S)-2-amino-3,6-dimethyl-6-(7-pyridin-3-yl-1-benzothiophen-3-yl)-5H-pyrimidin-4-one.

Molecular Properties

Compound Name(5S,6S)-2-amino-5-[4-(1,1-difluoroethyl)phenyl]-3,6-dimethyl-6-[3-(trifluoromethyl)phenyl]-5H-pyrimidin-4-one;(5R,6S)-2-amino-5-[4-(1,1-difluoroethyl)phenyl]-3,6-dimethyl-6-[3-(trifluoromethyl)phenyl]-5H-pyrimidin-4-one;3-[3-[(4S,5S)-2-amino-1,4-dimethyl-6-oxo-5-prop-2-ynyl-5H-pyrimidin-4-yl]phenyl]benzonitrile;3-[3-[(4S,5R)-2-amino-1,4-dimethyl-6-oxo-5-prop-2-ynyl-5H-pyrimidin-4-yl]phenyl]benzonitrile;3-[3-[(4S)-2-amino-1,4-dimethyl-6-oxo-5H-pyrimidin-4-yl]piperidin-1-yl]sulfonylbenzonitrile;(6S)-2-amino-3,6-dimethyl-6-(7-pyridin-3-yl-1-benzothiophen-3-yl)-5H-pyrimidin-4-one
PubChem CID159598404
Molecular FormulaC123H121F10N23O8S2
Molecular Weight2303.59 g/mol
Exact Mass2301.91
IUPAC Name(5S,6S)-2-amino-5-[4-(1,1-difluoroethyl)phenyl]-3,6-dimethyl-6-[3-(trifluoromethyl)phenyl]-5H-pyrimidin-4-one;(5R,6S)-2-amino-5-[4-(1,1-difluoroethyl)phenyl]-3,6-dimethyl-6-[3-(trifluoromethyl)phenyl]-5H-pyrimidin-4-one;3-[3-[(4S,5S)-2-amino-1,4-dimethyl-6-oxo-5-prop-2-ynyl-5H-pyrimidin-4-yl]phenyl]benzonitrile;3-[3-[(4S,5R)-2-amino-1,4-dimethyl-6-oxo-5-prop-2-ynyl-5H-pyrimidin-4-yl]phenyl]benzonitrile;3-[3-[(4S)-2-amino-1,4-dimethyl-6-oxo-5H-pyrimidin-4-yl]piperidin-1-yl]sulfonylbenzonitrile;(6S)-2-amino-3,6-dimethyl-6-(7-pyridin-3-yl-1-benzothiophen-3-yl)-5H-pyrimidin-4-one
SMILESC#CC[C@@H]1C(=O)N(C)C(N)=N[C@]1(C)c1cccc(-c2cccc(C#N)c2)c1.C#CC[C@H]1C(=O)N(C)C(N)=N[C@]1(C)c1cccc(-c2cccc(C#N)c2)c1.CN1C(=O)C[C@@](C)(C2CCCN(S(=O)(=O)c3cccc(C#N)c3)C2)N=C1N.CN1C(=O)C[C@@](C)(c2csc3c(-c4cccnc4)cccc23)N=C1N.CN1C(=O)[C@@H](c2ccc(C(C)(F)F)cc2)[C@@](C)(c2cccc(C(F)(F)F)c2)N=C1N.CN1C(=O)[C@H](c2ccc(C(C)(F)F)cc2)[C@@](C)(c2cccc(C(F)(F)F)c2)N=C1N
InChIInChI=1S/2C22H20N4O.2C21H20F5N3O.C19H18N4OS.C18H23N5O3S/c2*1-4-7-19-20(27)26(3)21(24)25-22(19,2)18-11-6-10-17(13-18)16-9-5-8-15(12-16)14-23;2*1-19(14-5-4-6-15(11-14)21(24,25)26)16(17(30)29(3)18(27)28-19)12-7-9-13(10-8-12)20(2,22)23;1-19(9-16(24)23(2)18(20)22-19)15-11-25-17-13(6-3-7-14(15)17)12-5-4-8-21-10-12;1-18(10-16(24)22(2)17(20)21-18)14-6-4-8-23(12-14)27(25,26)15-7-3-5-13(9-15)11-19/h2*1,5-6,8-13,19H,7H2,2-3H3,(H2,24,25);2*4-11,16H,1-3H3,(H2,27,28);3-8,10-11H,9H2,1-2H3,(H2,20,22);3,5,7,9,14H,4,6,8,10,12H2,1-2H3,(H2,20,21)/t19-,22+;19-,22-;16-,19+;16-,19-;19-;14?,18-/m010100/s1
InChIKeyMLDMIIDWRCMMNS-KDHGKMBRSA-N
XLogP19.19
TPSA473.78 Ų
H-Bond Donors6
H-Bond Acceptors25
Rotatable Bonds17
Heavy Atoms166
Complexity—

Lipinski Rule of Five

4 violations

RuleValue
MW ≤ 5002303.59
LogP ≤ 519.19
H-Bond Donors ≤ 56
H-Bond Acceptors ≤ 1025

Computed Properties (RDKit)

Structural Alerts{'alert_name': 'triple_bond', 'substructure': 'N/A'}

Analyze (5S,6S)-2-amino-5-[4-(1,1-difluoroethyl)phenyl]-3,6-dimethyl-6-[3-(trifluoromethyl)phenyl]-5H-pyrimidin-4-one;(5R,6S)-2-amino-5-[4-(1,1-difluoroethyl)phenyl]-3,6-dimethyl-6-[3-(trifluoromethyl)phenyl]-5H-pyrimidin-4-one;3-[3-[(4S,5S)-2-amino-1,4-dimethyl-6-oxo-5-prop-2-ynyl-5H-pyrimidin-4-yl]phenyl]benzonitrile;3-[3-[(4S,5R)-2-amino-1,4-dimethyl-6-oxo-5-prop-2-ynyl-5H-pyrimidin-4-yl]phenyl]benzonitrile;3-[3-[(4S)-2-amino-1,4-dimethyl-6-oxo-5H-pyrimidin-4-yl]piperidin-1-yl]sulfonylbenzonitrile;(6S)-2-amino-3,6-dimethyl-6-(7-pyridin-3-yl-1-benzothiophen-3-yl)-5H-pyrimidin-4-one with MolForge

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Frequently Asked Questions

What is the IUPAC name of (5S,6S)-2-amino-5-[4-(1,1-difluoroethyl)phenyl]-3,6-dimethyl-6-[3-(trifluoromethyl)phenyl]-5H-pyrimidin-4-one;(5R,6S)-2-amino-5-[4-(1,1-difluoroethyl)phenyl]-3,6-dimethyl-6-[3-(trifluoromethyl)phenyl]-5H-pyrimidin-4-one;3-[3-[(4S,5S)-2-amino-1,4-dimethyl-6-oxo-5-prop-2-ynyl-5H-pyrimidin-4-yl]phenyl]benzonitrile;3-[3-[(4S,5R)-2-amino-1,4-dimethyl-6-oxo-5-prop-2-ynyl-5H-pyrimidin-4-yl]phenyl]benzonitrile;3-[3-[(4S)-2-amino-1,4-dimethyl-6-oxo-5H-pyrimidin-4-yl]piperidin-1-yl]sulfonylbenzonitrile;(6S)-2-amino-3,6-dimethyl-6-(7-pyridin-3-yl-1-benzothiophen-3-yl)-5H-pyrimidin-4-one?
The IUPAC name of (5S,6S)-2-amino-5-[4-(1,1-difluoroethyl)phenyl]-3,6-dimethyl-6-[3-(trifluoromethyl)phenyl]-5H-pyrimidin-4-one;(5R,6S)-2-amino-5-[4-(1,1-difluoroethyl)phenyl]-3,6-dimethyl-6-[3-(trifluoromethyl)phenyl]-5H-pyrimidin-4-one;3-[3-[(4S,5S)-2-amino-1,4-dimethyl-6-oxo-5-prop-2-ynyl-5H-pyrimidin-4-yl]phenyl]benzonitrile;3-[3-[(4S,5R)-2-amino-1,4-dimethyl-6-oxo-5-prop-2-ynyl-5H-pyrimidin-4-yl]phenyl]benzonitrile;3-[3-[(4S)-2-amino-1,4-dimethyl-6-oxo-5H-pyrimidin-4-yl]piperidin-1-yl]sulfonylbenzonitrile;(6S)-2-amino-3,6-dimethyl-6-(7-pyridin-3-yl-1-benzothiophen-3-yl)-5H-pyrimidin-4-one (CID 159598404) is (5S,6S)-2-amino-5-[4-(1,1-difluoroethyl)phenyl]-3,6-dimethyl-6-[3-(trifluoromethyl)phenyl]-5H-pyrimidin-4-one;(5R,6S)-2-amino-5-[4-(1,1-difluoroethyl)phenyl]-3,6-dimethyl-6-[3-(trifluoromethyl)phenyl]-5H-pyrimidin-4-one;3-[3-[(4S,5S)-2-amino-1,4-dimethyl-6-oxo-5-prop-2-ynyl-5H-pyrimidin-4-yl]phenyl]benzonitrile;3-[3-[(4S,5R)-2-amino-1,4-dimethyl-6-oxo-5-prop-2-ynyl-5H-pyrimidin-4-yl]phenyl]benzonitrile;3-[3-[(4S)-2-amino-1,4-dimethyl-6-oxo-5H-pyrimidin-4-yl]piperidin-1-yl]sulfonylbenzonitrile;(6S)-2-amino-3,6-dimethyl-6-(7-pyridin-3-yl-1-benzothiophen-3-yl)-5H-pyrimidin-4-one.
What is the SMILES notation for (5S,6S)-2-amino-5-[4-(1,1-difluoroethyl)phenyl]-3,6-dimethyl-6-[3-(trifluoromethyl)phenyl]-5H-pyrimidin-4-one;(5R,6S)-2-amino-5-[4-(1,1-difluoroethyl)phenyl]-3,6-dimethyl-6-[3-(trifluoromethyl)phenyl]-5H-pyrimidin-4-one;3-[3-[(4S,5S)-2-amino-1,4-dimethyl-6-oxo-5-prop-2-ynyl-5H-pyrimidin-4-yl]phenyl]benzonitrile;3-[3-[(4S,5R)-2-amino-1,4-dimethyl-6-oxo-5-prop-2-ynyl-5H-pyrimidin-4-yl]phenyl]benzonitrile;3-[3-[(4S)-2-amino-1,4-dimethyl-6-oxo-5H-pyrimidin-4-yl]piperidin-1-yl]sulfonylbenzonitrile;(6S)-2-amino-3,6-dimethyl-6-(7-pyridin-3-yl-1-benzothiophen-3-yl)-5H-pyrimidin-4-one?
The canonical SMILES for (5S,6S)-2-amino-5-[4-(1,1-difluoroethyl)phenyl]-3,6-dimethyl-6-[3-(trifluoromethyl)phenyl]-5H-pyrimidin-4-one;(5R,6S)-2-amino-5-[4-(1,1-difluoroethyl)phenyl]-3,6-dimethyl-6-[3-(trifluoromethyl)phenyl]-5H-pyrimidin-4-one;3-[3-[(4S,5S)-2-amino-1,4-dimethyl-6-oxo-5-prop-2-ynyl-5H-pyrimidin-4-yl]phenyl]benzonitrile;3-[3-[(4S,5R)-2-amino-1,4-dimethyl-6-oxo-5-prop-2-ynyl-5H-pyrimidin-4-yl]phenyl]benzonitrile;3-[3-[(4S)-2-amino-1,4-dimethyl-6-oxo-5H-pyrimidin-4-yl]piperidin-1-yl]sulfonylbenzonitrile;(6S)-2-amino-3,6-dimethyl-6-(7-pyridin-3-yl-1-benzothiophen-3-yl)-5H-pyrimidin-4-one is C#CC[C@@H]1C(=O)N(C)C(N)=N[C@]1(C)c1cccc(-c2cccc(C#N)c2)c1.C#CC[C@H]1C(=O)N(C)C(N)=N[C@]1(C)c1cccc(-c2cccc(C#N)c2)c1.CN1C(=O)C[C@@](C)(C2CCCN(S(=O)(=O)c3cccc(C#N)c3)C2)N=C1N.CN1C(=O)C[C@@](C)(c2csc3c(-c4cccnc4)cccc23)N=C1N.CN1C(=O)[C@@H](c2ccc(C(C)(F)F)cc2)[C@@](C)(c2cccc(C(F)(F)F)c2)N=C1N.CN1C(=O)[C@H](c2ccc(C(C)(F)F)cc2)[C@@](C)(c2cccc(C(F)(F)F)c2)N=C1N.
What is the InChIKey of (5S,6S)-2-amino-5-[4-(1,1-difluoroethyl)phenyl]-3,6-dimethyl-6-[3-(trifluoromethyl)phenyl]-5H-pyrimidin-4-one;(5R,6S)-2-amino-5-[4-(1,1-difluoroethyl)phenyl]-3,6-dimethyl-6-[3-(trifluoromethyl)phenyl]-5H-pyrimidin-4-one;3-[3-[(4S,5S)-2-amino-1,4-dimethyl-6-oxo-5-prop-2-ynyl-5H-pyrimidin-4-yl]phenyl]benzonitrile;3-[3-[(4S,5R)-2-amino-1,4-dimethyl-6-oxo-5-prop-2-ynyl-5H-pyrimidin-4-yl]phenyl]benzonitrile;3-[3-[(4S)-2-amino-1,4-dimethyl-6-oxo-5H-pyrimidin-4-yl]piperidin-1-yl]sulfonylbenzonitrile;(6S)-2-amino-3,6-dimethyl-6-(7-pyridin-3-yl-1-benzothiophen-3-yl)-5H-pyrimidin-4-one?
The InChIKey is MLDMIIDWRCMMNS-KDHGKMBRSA-N. The full InChI is InChI=1S/2C22H20N4O.2C21H20F5N3O.C19H18N4OS.C18H23N5O3S/c2*1-4-7-19-20(27)26(3)21(24)25-22(19,2)18-11-6-10-17(13-18)16-9-5-8-15(12-16)14-23;2*1-19(14-5-4-6-15(11-14)21(24,25)26)16(17(30)29(3)18(27)28-19)12-7-9-13(10-8-12)20(2,22)23;1-19(9-16(24)23(2)18(20)22-19)15-11-25-17-13(6-3-7-14(15)17)12-5-4-8-21-10-12;1-18(10-16(24)22(2)17(20)21-18)14-6-4-8-23(12-14)27(25,26)15-7-3-5-13(9-15)11-19/h2*1,5-6,8-13,19H,7H2,2-3H3,(H2,24,25);2*4-11,16H,1-3H3,(H2,27,28);3-8,10-11H,9H2,1-2H3,(H2,20,22);3,5,7,9,14H,4,6,8,10,12H2,1-2H3,(H2,20,21)/t19-,22+;19-,22-;16-,19+;16-,19-;19-;14?,18-/m010100/s1.
What are the key properties of (5S,6S)-2-amino-5-[4-(1,1-difluoroethyl)phenyl]-3,6-dimethyl-6-[3-(trifluoromethyl)phenyl]-5H-pyrimidin-4-one;(5R,6S)-2-amino-5-[4-(1,1-difluoroethyl)phenyl]-3,6-dimethyl-6-[3-(trifluoromethyl)phenyl]-5H-pyrimidin-4-one;3-[3-[(4S,5S)-2-amino-1,4-dimethyl-6-oxo-5-prop-2-ynyl-5H-pyrimidin-4-yl]phenyl]benzonitrile;3-[3-[(4S,5R)-2-amino-1,4-dimethyl-6-oxo-5-prop-2-ynyl-5H-pyrimidin-4-yl]phenyl]benzonitrile;3-[3-[(4S)-2-amino-1,4-dimethyl-6-oxo-5H-pyrimidin-4-yl]piperidin-1-yl]sulfonylbenzonitrile;(6S)-2-amino-3,6-dimethyl-6-(7-pyridin-3-yl-1-benzothiophen-3-yl)-5H-pyrimidin-4-one?
(5S,6S)-2-amino-5-[4-(1,1-difluoroethyl)phenyl]-3,6-dimethyl-6-[3-(trifluoromethyl)phenyl]-5H-pyrimidin-4-one;(5R,6S)-2-amino-5-[4-(1,1-difluoroethyl)phenyl]-3,6-dimethyl-6-[3-(trifluoromethyl)phenyl]-5H-pyrimidin-4-one;3-[3-[(4S,5S)-2-amino-1,4-dimethyl-6-oxo-5-prop-2-ynyl-5H-pyrimidin-4-yl]phenyl]benzonitrile;3-[3-[(4S,5R)-2-amino-1,4-dimethyl-6-oxo-5-prop-2-ynyl-5H-pyrimidin-4-yl]phenyl]benzonitrile;3-[3-[(4S)-2-amino-1,4-dimethyl-6-oxo-5H-pyrimidin-4-yl]piperidin-1-yl]sulfonylbenzonitrile;(6S)-2-amino-3,6-dimethyl-6-(7-pyridin-3-yl-1-benzothiophen-3-yl)-5H-pyrimidin-4-one has a molecular weight of 2303.59 g/mol, XLogP of 19.19, 17 rotatable bonds, 6 hydrogen bond donors, and 25 hydrogen bond acceptors.
Where does this data come from?
All data for (5S,6S)-2-amino-5-[4-(1,1-difluoroethyl)phenyl]-3,6-dimethyl-6-[3-(trifluoromethyl)phenyl]-5H-pyrimidin-4-one;(5R,6S)-2-amino-5-[4-(1,1-difluoroethyl)phenyl]-3,6-dimethyl-6-[3-(trifluoromethyl)phenyl]-5H-pyrimidin-4-one;3-[3-[(4S,5S)-2-amino-1,4-dimethyl-6-oxo-5-prop-2-ynyl-5H-pyrimidin-4-yl]phenyl]benzonitrile;3-[3-[(4S,5R)-2-amino-1,4-dimethyl-6-oxo-5-prop-2-ynyl-5H-pyrimidin-4-yl]phenyl]benzonitrile;3-[3-[(4S)-2-amino-1,4-dimethyl-6-oxo-5H-pyrimidin-4-yl]piperidin-1-yl]sulfonylbenzonitrile;(6S)-2-amino-3,6-dimethyl-6-(7-pyridin-3-yl-1-benzothiophen-3-yl)-5H-pyrimidin-4-one is sourced from PubChem (CID 159598404), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).