N-[5-(4-chloro-1H-benzimidazol-2-yl)-1H-pyrazol-4-yl]-2,6-difluorobenzamide;N-[5-(4,5-difluoro-1H-benzimidazol-2-yl)-1H-pyrazol-4-yl]-2,6-difluorobenzamide;2,6-difluoro-N-[5-[6-(1-methylpiperidin-4-yl)oxy-1H-benzimidazol-2-yl]-1H-pyrazol-4-yl]benzamide;2,6-difluoro-N-[5-[6-(2-pyrrolidin-1-ylethoxy)-1H-benzimidazol-2-yl]-1H-pyrazol-4-yl]benzamide;2,6-difluoro-N-[5-(4,5,6,7-tetrafluoro-1H-benzimidazol-2-yl)-1H-pyrazol-4-yl]benzamide;N-[5-(5,6-dimethyl-1H-benzimidazol-2-yl)-1H-pyrazol-4-yl]-4-methylbenzamide

C117H89ClF16N32O8 — CID 159610933

About N-[5-(4-chloro-1H-benzimidazol-2-yl)-1H-pyrazol-4-yl]-2,6-difluorobenzamide;N-[5-(4,5-difluoro-1H-benzimidazol-2-yl)-1H-pyrazol-4-yl]-2,6-difluorobenzamide;2,6-difluoro-N-[5-[6-(1-methylpiperidin-4-yl)oxy-1H-benzimidazol-2-yl]-1H-pyrazol-4-yl]benzamide;2,6-difluoro-N-[5-[6-(2-pyrrolidin-1-ylethoxy)-1H-benzimidazol-2-yl]-1H-pyrazol-4-yl]benzamide;2,6-difluoro-N-[5-(4,5,6,7-tetrafluoro-1H-benzimidazol-2-yl)-1H-pyrazol-4-yl]benzamide;N-[5-(5,6-dimethyl-1H-benzimidazol-2-yl)-1H-pyrazol-4-yl]-4-methylbenzamide

N-[5-(4-chloro-1H-benzimidazol-2-yl)-1H-pyrazol-4-yl]-2,6-difluorobenzamide;N-[5-(4,5-difluoro-1H-benzimidazol-2-yl)-1H-pyrazol-4-yl]-2,6-difluorobenzamide;2,6-difluoro-N-[5-[6-(1-methylpiperidin-4-yl)oxy-1H-benzimidazol-2-yl]-1H-pyrazol-4-yl]benzamide;2,6-difluoro-N-[5-[6-(2-pyrrolidin-1-ylethoxy)-1H-benzimidazol-2-yl]-1H-pyrazol-4-yl]benzamide;2,6-difluoro-N-[5-(4,5,6,7-tetrafluoro-1H-benzimidazol-2-yl)-1H-pyrazol-4-yl]benzamide;N-[5-(5,6-dimethyl-1H-benzimidazol-2-yl)-1H-pyrazol-4-yl]-4-methylbenzamide (PubChem CID 159610933) has the molecular formula C117H89ClF16N32O8 and a molecular weight of 2410.64 g/mol. Its IUPAC name is N-[5-(4-chloro-1H-benzimidazol-2-yl)-1H-pyrazol-4-yl]-2,6-difluorobenzamide;N-[5-(4,5-difluoro-1H-benzimidazol-2-yl)-1H-pyrazol-4-yl]-2,6-difluorobenzamide;2,6-difluoro-N-[5-[6-(1-methylpiperidin-4-yl)oxy-1H-benzimidazol-2-yl]-1H-pyrazol-4-yl]benzamide;2,6-difluoro-N-[5-[6-(2-pyrrolidin-1-ylethoxy)-1H-benzimidazol-2-yl]-1H-pyrazol-4-yl]benzamide;2,6-difluoro-N-[5-(4,5,6,7-tetrafluoro-1H-benzimidazol-2-yl)-1H-pyrazol-4-yl]benzamide;N-[5-(5,6-dimethyl-1H-benzimidazol-2-yl)-1H-pyrazol-4-yl]-4-methylbenzamide.

Molecular Properties

• Compound Name: N-[5-(4-chloro-1H-benzimidazol-2-yl)-1H-pyrazol-4-yl]-2,6-difluorobenzamide;N-[5-(4,5-difluoro-1H-benzimidazol-2-yl)-1H-pyrazol-4-yl]-2,6-difluorobenzamide;2,6-difluoro-N-[5-[6-(1-methylpiperidin-4-yl)oxy-1H-benzimidazol-2-yl]-1H-pyrazol-4-yl]benzamide;2,6-difluoro-N-[5-[6-(2-pyrrolidin-1-ylethoxy)-1H-benzimidazol-2-yl]-1H-pyrazol-4-yl]benzamide;2,6-difluoro-N-[5-(4,5,6,7-tetrafluoro-1H-benzimidazol-2-yl)-1H-pyrazol-4-yl]benzamide;N-[5-(5,6-dimethyl-1H-benzimidazol-2-yl)-1H-pyrazol-4-yl]-4-methylbenzamide
• PubChem CID: 159610933
• Molecular Formula: C117H89ClF16N32O8
• Molecular Weight: 2410.64 g/mol
• Exact Mass: 2408.70
• IUPAC Name: N-[5-(4-chloro-1H-benzimidazol-2-yl)-1H-pyrazol-4-yl]-2,6-difluorobenzamide;N-[5-(4,5-difluoro-1H-benzimidazol-2-yl)-1H-pyrazol-4-yl]-2,6-difluorobenzamide;2,6-difluoro-N-[5-[6-(1-methylpiperidin-4-yl)oxy-1H-benzimidazol-2-yl]-1H-pyrazol-4-yl]benzamide;2,6-difluoro-N-[5-[6-(2-pyrrolidin-1-ylethoxy)-1H-benzimidazol-2-yl]-1H-pyrazol-4-yl]benzamide;2,6-difluoro-N-[5-(4,5,6,7-tetrafluoro-1H-benzimidazol-2-yl)-1H-pyrazol-4-yl]benzamide;N-[5-(5,6-dimethyl-1H-benzimidazol-2-yl)-1H-pyrazol-4-yl]-4-methylbenzamide
• SMILES: CN1CCC(Oc2ccc3nc(-c4[nH]ncc4NC(=O)c4c(F)cccc4F)[nH]c3c2)CC1.Cc1ccc(C(=O)Nc2cn[nH]c2-c2nc3cc(C)c(C)cc3[nH]2)cc1.O=C(Nc1cn[nH]c1-c1nc2c(Cl)cccc2[nH]1)c1c(F)cccc1F.O=C(Nc1cn[nH]c1-c1nc2c(F)c(F)c(F)c(F)c2[nH]1)c1c(F)cccc1F.O=C(Nc1cn[nH]c1-c1nc2c(F)c(F)ccc2[nH]1)c1c(F)cccc1F.O=C(Nc1cn[nH]c1-c1nc2ccc(OCCN3CCCC3)cc2[nH]1)c1c(F)cccc1F
• InChI: InChI=1S/2C23H22F2N6O2.C20H19N5O.C17H10ClF2N5O.C17H7F6N5O.C17H9F4N5O/c1-31-9-7-13(8-10-31)33-14-5-6-17-18(11-14)28-22(27-17)21-19(12-26-30-21)29-23(32)20-15(24)3-2-4-16(20)25;24-15-4-3-5-16(25)20(15)23(32)29-19-13-26-30-21(19)22-27-17-7-6-14(12-18(17)28-22)33-11-10-31-8-1-2-9-31;1-11-4-6-14(7-5-11)20(26)24-17-10-21-25-18(17)19-22-15-8-12(2)13(3)9-16(15)23-19;18-8-3-1-6-11-14(8)24-16(22-11)15-12(7-21-25-15)23-17(26)13-9(19)4-2-5-10(13)20;18-5-2-1-3-6(19)8(5)17(29)25-7-4-24-28-13(7)16-26-14-11(22)9(20)10(21)12(23)15(14)27-16;18-7-2-1-3-8(19)12(7)17(27)24-11-6-22-26-15(11)16-23-10-5-4-9(20)13(21)14(10)25-16/h2-6,11-13H,7-10H2,1H3,(H,26,30)(H,27,28)(H,29,32);3-7,12-13H,1-2,8-11H2,(H,26,30)(H,27,28)(H,29,32);4-10H,1-3H3,(H,21,25)(H,22,23)(H,24,26);1-7H,(H,21,25)(H,22,24)(H,23,26);1-4H,(H,24,28)(H,25,29)(H,26,27);1-6H,(H,22,26)(H,23,25)(H,24,27)
• InChIKey: MMRIEJVJMWFDNL-UHFFFAOYSA-N
• XLogP: 23.98
• TPSA: 543.70 Ų
• H-Bond Donors: 18
• H-Bond Acceptors: 22
• Rotatable Bonds: 24
• Heavy Atoms: 174
• Complexity: —

Lipinski Rule of Five

4 violations

Rule	Value
MW ≤ 500	2410.64
LogP ≤ 5	23.98
H-Bond Donors ≤ 5	18
H-Bond Acceptors ≤ 10	22

Computed Properties (RDKit)

• Structural Alerts: {'alert_name': 'halogenated_ring_1', 'substructure': 'N/A'}, {'alert_name': 'halogenated_ring_2', 'substructure': 'N/A'}

Frequently Asked Questions

What is the IUPAC name of N-[5-(4-chloro-1H-benzimidazol-2-yl)-1H-pyrazol-4-yl]-2,6-difluorobenzamide;N-[5-(4,5-difluoro-1H-benzimidazol-2-yl)-1H-pyrazol-4-yl]-2,6-difluorobenzamide;2,6-difluoro-N-[5-[6-(1-methylpiperidin-4-yl)oxy-1H-benzimidazol-2-yl]-1H-pyrazol-4-yl]benzamide;2,6-difluoro-N-[5-[6-(2-pyrrolidin-1-ylethoxy)-1H-benzimidazol-2-yl]-1H-pyrazol-4-yl]benzamide;2,6-difluoro-N-[5-(4,5,6,7-tetrafluoro-1H-benzimidazol-2-yl)-1H-pyrazol-4-yl]benzamide;N-[5-(5,6-dimethyl-1H-benzimidazol-2-yl)-1H-pyrazol-4-yl]-4-methylbenzamide?

The IUPAC name of N-[5-(4-chloro-1H-benzimidazol-2-yl)-1H-pyrazol-4-yl]-2,6-difluorobenzamide;N-[5-(4,5-difluoro-1H-benzimidazol-2-yl)-1H-pyrazol-4-yl]-2,6-difluorobenzamide;2,6-difluoro-N-[5-[6-(1-methylpiperidin-4-yl)oxy-1H-benzimidazol-2-yl]-1H-pyrazol-4-yl]benzamide;2,6-difluoro-N-[5-[6-(2-pyrrolidin-1-ylethoxy)-1H-benzimidazol-2-yl]-1H-pyrazol-4-yl]benzamide;2,6-difluoro-N-[5-(4,5,6,7-tetrafluoro-1H-benzimidazol-2-yl)-1H-pyrazol-4-yl]benzamide;N-[5-(5,6-dimethyl-1H-benzimidazol-2-yl)-1H-pyrazol-4-yl]-4-methylbenzamide (CID 159610933) is N-[5-(4-chloro-1H-benzimidazol-2-yl)-1H-pyrazol-4-yl]-2,6-difluorobenzamide;N-[5-(4,5-difluoro-1H-benzimidazol-2-yl)-1H-pyrazol-4-yl]-2,6-difluorobenzamide;2,6-difluoro-N-[5-[6-(1-methylpiperidin-4-yl)oxy-1H-benzimidazol-2-yl]-1H-pyrazol-4-yl]benzamide;2,6-difluoro-N-[5-[6-(2-pyrrolidin-1-ylethoxy)-1H-benzimidazol-2-yl]-1H-pyrazol-4-yl]benzamide;2,6-difluoro-N-[5-(4,5,6,7-tetrafluoro-1H-benzimidazol-2-yl)-1H-pyrazol-4-yl]benzamide;N-[5-(5,6-dimethyl-1H-benzimidazol-2-yl)-1H-pyrazol-4-yl]-4-methylbenzamide.

What is the SMILES notation for N-[5-(4-chloro-1H-benzimidazol-2-yl)-1H-pyrazol-4-yl]-2,6-difluorobenzamide;N-[5-(4,5-difluoro-1H-benzimidazol-2-yl)-1H-pyrazol-4-yl]-2,6-difluorobenzamide;2,6-difluoro-N-[5-[6-(1-methylpiperidin-4-yl)oxy-1H-benzimidazol-2-yl]-1H-pyrazol-4-yl]benzamide;2,6-difluoro-N-[5-[6-(2-pyrrolidin-1-ylethoxy)-1H-benzimidazol-2-yl]-1H-pyrazol-4-yl]benzamide;2,6-difluoro-N-[5-(4,5,6,7-tetrafluoro-1H-benzimidazol-2-yl)-1H-pyrazol-4-yl]benzamide;N-[5-(5,6-dimethyl-1H-benzimidazol-2-yl)-1H-pyrazol-4-yl]-4-methylbenzamide?

The canonical SMILES for N-[5-(4-chloro-1H-benzimidazol-2-yl)-1H-pyrazol-4-yl]-2,6-difluorobenzamide;N-[5-(4,5-difluoro-1H-benzimidazol-2-yl)-1H-pyrazol-4-yl]-2,6-difluorobenzamide;2,6-difluoro-N-[5-[6-(1-methylpiperidin-4-yl)oxy-1H-benzimidazol-2-yl]-1H-pyrazol-4-yl]benzamide;2,6-difluoro-N-[5-[6-(2-pyrrolidin-1-ylethoxy)-1H-benzimidazol-2-yl]-1H-pyrazol-4-yl]benzamide;2,6-difluoro-N-[5-(4,5,6,7-tetrafluoro-1H-benzimidazol-2-yl)-1H-pyrazol-4-yl]benzamide;N-[5-(5,6-dimethyl-1H-benzimidazol-2-yl)-1H-pyrazol-4-yl]-4-methylbenzamide is CN1CCC(Oc2ccc3nc(-c4[nH]ncc4NC(=O)c4c(F)cccc4F)[nH]c3c2)CC1.Cc1ccc(C(=O)Nc2cn[nH]c2-c2nc3cc(C)c(C)cc3[nH]2)cc1.O=C(Nc1cn[nH]c1-c1nc2c(Cl)cccc2[nH]1)c1c(F)cccc1F.O=C(Nc1cn[nH]c1-c1nc2c(F)c(F)c(F)c(F)c2[nH]1)c1c(F)cccc1F.O=C(Nc1cn[nH]c1-c1nc2c(F)c(F)ccc2[nH]1)c1c(F)cccc1F.O=C(Nc1cn[nH]c1-c1nc2ccc(OCCN3CCCC3)cc2[nH]1)c1c(F)cccc1F.

What is the InChIKey of N-[5-(4-chloro-1H-benzimidazol-2-yl)-1H-pyrazol-4-yl]-2,6-difluorobenzamide;N-[5-(4,5-difluoro-1H-benzimidazol-2-yl)-1H-pyrazol-4-yl]-2,6-difluorobenzamide;2,6-difluoro-N-[5-[6-(1-methylpiperidin-4-yl)oxy-1H-benzimidazol-2-yl]-1H-pyrazol-4-yl]benzamide;2,6-difluoro-N-[5-[6-(2-pyrrolidin-1-ylethoxy)-1H-benzimidazol-2-yl]-1H-pyrazol-4-yl]benzamide;2,6-difluoro-N-[5-(4,5,6,7-tetrafluoro-1H-benzimidazol-2-yl)-1H-pyrazol-4-yl]benzamide;N-[5-(5,6-dimethyl-1H-benzimidazol-2-yl)-1H-pyrazol-4-yl]-4-methylbenzamide?

The InChIKey is MMRIEJVJMWFDNL-UHFFFAOYSA-N. The full InChI is InChI=1S/2C23H22F2N6O2.C20H19N5O.C17H10ClF2N5O.C17H7F6N5O.C17H9F4N5O/c1-31-9-7-13(8-10-31)33-14-5-6-17-18(11-14)28-22(27-17)21-19(12-26-30-21)29-23(32)20-15(24)3-2-4-16(20)25;24-15-4-3-5-16(25)20(15)23(32)29-19-13-26-30-21(19)22-27-17-7-6-14(12-18(17)28-22)33-11-10-31-8-1-2-9-31;1-11-4-6-14(7-5-11)20(26)24-17-10-21-25-18(17)19-22-15-8-12(2)13(3)9-16(15)23-19;18-8-3-1-6-11-14(8)24-16(22-11)15-12(7-21-25-15)23-17(26)13-9(19)4-2-5-10(13)20;18-5-2-1-3-6(19)8(5)17(29)25-7-4-24-28-13(7)16-26-14-11(22)9(20)10(21)12(23)15(14)27-16;18-7-2-1-3-8(19)12(7)17(27)24-11-6-22-26-15(11)16-23-10-5-4-9(20)13(21)14(10)25-16/h2-6,11-13H,7-10H2,1H3,(H,26,30)(H,27,28)(H,29,32);3-7,12-13H,1-2,8-11H2,(H,26,30)(H,27,28)(H,29,32);4-10H,1-3H3,(H,21,25)(H,22,23)(H,24,26);1-7H,(H,21,25)(H,22,24)(H,23,26);1-4H,(H,24,28)(H,25,29)(H,26,27);1-6H,(H,22,26)(H,23,25)(H,24,27).

What are the key properties of N-[5-(4-chloro-1H-benzimidazol-2-yl)-1H-pyrazol-4-yl]-2,6-difluorobenzamide;N-[5-(4,5-difluoro-1H-benzimidazol-2-yl)-1H-pyrazol-4-yl]-2,6-difluorobenzamide;2,6-difluoro-N-[5-[6-(1-methylpiperidin-4-yl)oxy-1H-benzimidazol-2-yl]-1H-pyrazol-4-yl]benzamide;2,6-difluoro-N-[5-[6-(2-pyrrolidin-1-ylethoxy)-1H-benzimidazol-2-yl]-1H-pyrazol-4-yl]benzamide;2,6-difluoro-N-[5-(4,5,6,7-tetrafluoro-1H-benzimidazol-2-yl)-1H-pyrazol-4-yl]benzamide;N-[5-(5,6-dimethyl-1H-benzimidazol-2-yl)-1H-pyrazol-4-yl]-4-methylbenzamide?

N-[5-(4-chloro-1H-benzimidazol-2-yl)-1H-pyrazol-4-yl]-2,6-difluorobenzamide;N-[5-(4,5-difluoro-1H-benzimidazol-2-yl)-1H-pyrazol-4-yl]-2,6-difluorobenzamide;2,6-difluoro-N-[5-[6-(1-methylpiperidin-4-yl)oxy-1H-benzimidazol-2-yl]-1H-pyrazol-4-yl]benzamide;2,6-difluoro-N-[5-[6-(2-pyrrolidin-1-ylethoxy)-1H-benzimidazol-2-yl]-1H-pyrazol-4-yl]benzamide;2,6-difluoro-N-[5-(4,5,6,7-tetrafluoro-1H-benzimidazol-2-yl)-1H-pyrazol-4-yl]benzamide;N-[5-(5,6-dimethyl-1H-benzimidazol-2-yl)-1H-pyrazol-4-yl]-4-methylbenzamide has a molecular weight of 2410.64 g/mol, XLogP of 23.98, 24 rotatable bonds, 18 hydrogen bond donors, and 22 hydrogen bond acceptors.

Where does this data come from?

All data for N-[5-(4-chloro-1H-benzimidazol-2-yl)-1H-pyrazol-4-yl]-2,6-difluorobenzamide;N-[5-(4,5-difluoro-1H-benzimidazol-2-yl)-1H-pyrazol-4-yl]-2,6-difluorobenzamide;2,6-difluoro-N-[5-[6-(1-methylpiperidin-4-yl)oxy-1H-benzimidazol-2-yl]-1H-pyrazol-4-yl]benzamide;2,6-difluoro-N-[5-[6-(2-pyrrolidin-1-ylethoxy)-1H-benzimidazol-2-yl]-1H-pyrazol-4-yl]benzamide;2,6-difluoro-N-[5-(4,5,6,7-tetrafluoro-1H-benzimidazol-2-yl)-1H-pyrazol-4-yl]benzamide;N-[5-(5,6-dimethyl-1H-benzimidazol-2-yl)-1H-pyrazol-4-yl]-4-methylbenzamide is sourced from PubChem (CID 159610933), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).