3-[6-[2-(3-chloro-4-fluorophenyl)-3-pyridinyl]quinazolin-4-yl]oxy-N,N-dimethylpropan-1-amine;6-[2-(4-fluoro-3-methylphenyl)-3-pyridinyl]-4-[2-(4-methylpiperazin-1-yl)ethoxy]quinazoline;6-[2-(4-fluoro-3-methylphenyl)-3-pyridinyl]-4-[3-(4-methylpiperazin-1-yl)propoxy]quinazoline;6-[2-(4-fluoro-3-methylphenyl)-3-pyridinyl]-4-[(6-methyl-3-pyridinyl)oxy]quinazoline;1-[3-[6-[2-(4-fluoro-3-methylphenyl)-3-pyridinyl]quinazolin-4-yl]oxypropyl]pyrrolidin-2-one

C132H124ClF5N22O6 — CID 159621308

IUPAC3-[6-[2-(3-chloro-4-fluorophenyl)-3-pyridinyl]quinazolin-4-yl]oxy-N,N-dimethylpropan-1-amine;6-[2-(4-fluoro-3-methylphenyl)-3-pyridinyl]-4-[2-(4-methylpiperazin-1-yl)ethoxy]quinazoline;6-[2-(4-fluoro-3-methylphenyl)-3-pyridinyl]-4-[3-(4-methylpiperazin-1-yl)propoxy]quinazoline;6-[2-(4-fluoro-3-methylphenyl)-3-pyridinyl]-4-[(6-methyl-3-pyridinyl)oxy]quinazoline;1-[3-[6-[2-(4-fluoro-3-methylphenyl)-3-pyridinyl]quinazolin-4-yl]oxypropyl]pyrrolidin-2-one
SMILESCN(C)CCCOc1ncnc2ccc(-c3cccnc3-c3ccc(F)c(Cl)c3)cc12.Cc1cc(-c2ncccc2-c2ccc3ncnc(OCCCN4CCCC4=O)c3c2)ccc1F.Cc1cc(-c2ncccc2-c2ccc3ncnc(OCCCN4CCN(C)CC4)c3c2)ccc1F.Cc1cc(-c2ncccc2-c2ccc3ncnc(OCCN4CCN(C)CC4)c3c2)ccc1F.Cc1ccc(Oc2ncnc3ccc(-c4cccnc4-c4ccc(F)c(C)c4)cc23)cn1
InChIInChI=1S/C28H30FN5O.C27H28FN5O.C27H25FN4O2.C26H19FN4O.C24H22ClFN4O/c1-20-17-22(6-8-25(20)29)27-23(5-3-10-30-27)21-7-9-26-24(18-21)28(32-19-31-26)35-16-4-11-34-14-12-33(2)13-15-34;1-19-16-21(5-7-24(19)28)26-22(4-3-9-29-26)20-6-8-25-23(17-20)27(31-18-30-25)34-15-14-33-12-10-32(2)11-13-33;1-18-15-20(7-9-23(18)28)26-21(5-2-11-29-26)19-8-10-24-22(16-19)27(31-17-30-24)34-14-4-13-32-12-3-6-25(32)33;1-16-12-19(6-9-23(16)27)25-21(4-3-11-28-25)18-7-10-24-22(13-18)26(31-15-30-24)32-20-8-5-17(2)29-14-20;1-30(2)11-4-12-31-24-19-13-16(7-9-22(19)28-15-29-24)18-5-3-10-27-23(18)17-6-8-21(26)20(25)14-17/h3,5-10,17-19H,4,11-16H2,1-2H3;3-9,16-18H,10-15H2,1-2H3;2,5,7-11,15-17H,3-4,6,12-14H2,1H3;3-15H,1-2H3;3,5-10,13-15H,4,11-12H2,1-2H3
InChIKeyMNXOVOBNNBZDBF-UHFFFAOYSA-N
MW2245.03 g/mol
LogP26.24
Rot. Bonds31

About 3-[6-[2-(3-chloro-4-fluorophenyl)-3-pyridinyl]quinazolin-4-yl]oxy-N,N-dimethylpropan-1-amine;6-[2-(4-fluoro-3-methylphenyl)-3-pyridinyl]-4-[2-(4-methylpiperazin-1-yl)ethoxy]quinazoline;6-[2-(4-fluoro-3-methylphenyl)-3-pyridinyl]-4-[3-(4-methylpiperazin-1-yl)propoxy]quinazoline;6-[2-(4-fluoro-3-methylphenyl)-3-pyridinyl]-4-[(6-methyl-3-pyridinyl)oxy]quinazoline;1-[3-[6-[2-(4-fluoro-3-methylphenyl)-3-pyridinyl]quinazolin-4-yl]oxypropyl]pyrrolidin-2-one

3-[6-[2-(3-chloro-4-fluorophenyl)-3-pyridinyl]quinazolin-4-yl]oxy-N,N-dimethylpropan-1-amine;6-[2-(4-fluoro-3-methylphenyl)-3-pyridinyl]-4-[2-(4-methylpiperazin-1-yl)ethoxy]quinazoline;6-[2-(4-fluoro-3-methylphenyl)-3-pyridinyl]-4-[3-(4-methylpiperazin-1-yl)propoxy]quinazoline;6-[2-(4-fluoro-3-methylphenyl)-3-pyridinyl]-4-[(6-methyl-3-pyridinyl)oxy]quinazoline;1-[3-[6-[2-(4-fluoro-3-methylphenyl)-3-pyridinyl]quinazolin-4-yl]oxypropyl]pyrrolidin-2-one (PubChem CID 159621308) has the molecular formula C132H124ClF5N22O6 and a molecular weight of 2245.03 g/mol. Its IUPAC name is 3-[6-[2-(3-chloro-4-fluorophenyl)-3-pyridinyl]quinazolin-4-yl]oxy-N,N-dimethylpropan-1-amine;6-[2-(4-fluoro-3-methylphenyl)-3-pyridinyl]-4-[2-(4-methylpiperazin-1-yl)ethoxy]quinazoline;6-[2-(4-fluoro-3-methylphenyl)-3-pyridinyl]-4-[3-(4-methylpiperazin-1-yl)propoxy]quinazoline;6-[2-(4-fluoro-3-methylphenyl)-3-pyridinyl]-4-[(6-methyl-3-pyridinyl)oxy]quinazoline;1-[3-[6-[2-(4-fluoro-3-methylphenyl)-3-pyridinyl]quinazolin-4-yl]oxypropyl]pyrrolidin-2-one.

Molecular Properties

Compound Name3-[6-[2-(3-chloro-4-fluorophenyl)-3-pyridinyl]quinazolin-4-yl]oxy-N,N-dimethylpropan-1-amine;6-[2-(4-fluoro-3-methylphenyl)-3-pyridinyl]-4-[2-(4-methylpiperazin-1-yl)ethoxy]quinazoline;6-[2-(4-fluoro-3-methylphenyl)-3-pyridinyl]-4-[3-(4-methylpiperazin-1-yl)propoxy]quinazoline;6-[2-(4-fluoro-3-methylphenyl)-3-pyridinyl]-4-[(6-methyl-3-pyridinyl)oxy]quinazoline;1-[3-[6-[2-(4-fluoro-3-methylphenyl)-3-pyridinyl]quinazolin-4-yl]oxypropyl]pyrrolidin-2-one
PubChem CID159621308
Molecular FormulaC132H124ClF5N22O6
Molecular Weight2245.03 g/mol
Exact Mass2242.97
IUPAC Name3-[6-[2-(3-chloro-4-fluorophenyl)-3-pyridinyl]quinazolin-4-yl]oxy-N,N-dimethylpropan-1-amine;6-[2-(4-fluoro-3-methylphenyl)-3-pyridinyl]-4-[2-(4-methylpiperazin-1-yl)ethoxy]quinazoline;6-[2-(4-fluoro-3-methylphenyl)-3-pyridinyl]-4-[3-(4-methylpiperazin-1-yl)propoxy]quinazoline;6-[2-(4-fluoro-3-methylphenyl)-3-pyridinyl]-4-[(6-methyl-3-pyridinyl)oxy]quinazoline;1-[3-[6-[2-(4-fluoro-3-methylphenyl)-3-pyridinyl]quinazolin-4-yl]oxypropyl]pyrrolidin-2-one
SMILESCN(C)CCCOc1ncnc2ccc(-c3cccnc3-c3ccc(F)c(Cl)c3)cc12.Cc1cc(-c2ncccc2-c2ccc3ncnc(OCCCN4CCCC4=O)c3c2)ccc1F.Cc1cc(-c2ncccc2-c2ccc3ncnc(OCCCN4CCN(C)CC4)c3c2)ccc1F.Cc1cc(-c2ncccc2-c2ccc3ncnc(OCCN4CCN(C)CC4)c3c2)ccc1F.Cc1ccc(Oc2ncnc3ccc(-c4cccnc4-c4ccc(F)c(C)c4)cc23)cn1
InChIInChI=1S/C28H30FN5O.C27H28FN5O.C27H25FN4O2.C26H19FN4O.C24H22ClFN4O/c1-20-17-22(6-8-25(20)29)27-23(5-3-10-30-27)21-7-9-26-24(18-21)28(32-19-31-26)35-16-4-11-34-14-12-33(2)13-15-34;1-19-16-21(5-7-24(19)28)26-22(4-3-9-29-26)20-6-8-25-23(17-20)27(31-18-30-25)34-15-14-33-12-10-32(2)11-13-33;1-18-15-20(7-9-23(18)28)26-21(5-2-11-29-26)19-8-10-24-22(16-19)27(31-17-30-24)34-14-4-13-32-12-3-6-25(32)33;1-16-12-19(6-9-23(16)27)25-21(4-3-11-28-25)18-7-10-24-22(13-18)26(31-15-30-24)32-20-8-5-17(2)29-14-20;1-30(2)11-4-12-31-24-19-13-16(7-9-22(19)28-15-29-24)18-5-3-10-27-23(18)17-6-8-21(26)20(25)14-17/h3,5-10,17-19H,4,11-16H2,1-2H3;3-9,16-18H,10-15H2,1-2H3;2,5,7-11,15-17H,3-4,6,12-14H2,1H3;3-15H,1-2H3;3,5-10,13-15H,4,11-12H2,1-2H3
InChIKeyMNXOVOBNNBZDBF-UHFFFAOYSA-N
XLogP26.24
TPSA288.90 Ų
H-Bond Donors
H-Bond Acceptors27
Rotatable Bonds31
Heavy Atoms166
Complexity—

Lipinski Rule of Five

3 violations

RuleValue
MW ≤ 5002245.03
LogP ≤ 526.24
H-Bond Donors ≤ 50
H-Bond Acceptors ≤ 1027

Computed Properties (RDKit)

Structural Alerts{'alert_name': 'Aliphatic_long_chain', 'substructure': 'N/A'}

Analyze 3-[6-[2-(3-chloro-4-fluorophenyl)-3-pyridinyl]quinazolin-4-yl]oxy-N,N-dimethylpropan-1-amine;6-[2-(4-fluoro-3-methylphenyl)-3-pyridinyl]-4-[2-(4-methylpiperazin-1-yl)ethoxy]quinazoline;6-[2-(4-fluoro-3-methylphenyl)-3-pyridinyl]-4-[3-(4-methylpiperazin-1-yl)propoxy]quinazoline;6-[2-(4-fluoro-3-methylphenyl)-3-pyridinyl]-4-[(6-methyl-3-pyridinyl)oxy]quinazoline;1-[3-[6-[2-(4-fluoro-3-methylphenyl)-3-pyridinyl]quinazolin-4-yl]oxypropyl]pyrrolidin-2-one with MolForge

Explore ADMET properties, 3D molecular structure, drug-likeness score, and discover similar compounds using our AI-powered platform.

Launch Full Analysis

Related Compounds

1-[3-[6-[2-(3-Chloro-4-fluorophenyl)-3-pyridinyl]quinazolin-4-yl]oxypropyl]pyrrolidin-2-one
CID 90094511
6-[2-(3-Chloro-4-fluorophenyl)-3-pyridinyl]-4-[(6-methyl-3-pyridinyl)oxy]quinazoline
CID 90094670
1-[4-[[2,4-Dichloro-8-[5-[[2,4-dichloro-3-(2,2,2-trifluoroethoxy)quinolin-6-yl]-hydroxy-[6-(trifluoromethyl)-3-pyridinyl]methyl]-1-methylimidazol-2-yl]-3-propan-2-yloxyquinolin-6-yl]-hydroxy-phenylmethyl]piperidin-1-yl]ethanone
CID 129035419
benzyl (2R)-4-[7-(8-chloro-7-fluoronaphthalen-1-yl)-2-[[(2S)-1-methylpyrrolidin-2-yl]methoxy]-8-(2,2,2-trifluoroethoxy)pyrido[4,3-d]pyrimidin-4-yl]-2-(isocyanomethyl)piperazine-1-carboxylate
CID 155630116
7-[2-(3-Chloro-4-fluorophenyl)-3-pyridinyl]quinazoline-2,4-diamine;6-[2-[3-(cyclopropylmethoxy)phenyl]-3-pyridinyl]quinazolin-4-amine;7-[2-(4-fluoro-3-methylphenyl)-3-pyridinyl]quinazoline-2,4-diamine;6-[2-(3-morpholin-4-ylphenyl)-3-pyridinyl]quinazolin-4-amine;6-[2-[3-(2,2,2-trifluoroethoxy)phenyl]-3-pyridinyl]quinazolin-4-amine
CID 157416471
(E)-1-[(2R)-4-[7-(8-chloronaphthalen-1-yl)-8-fluoro-2-[[(2S,4R)-4-methoxy-1-methylpyrrolidin-2-yl]methoxy]pyrido[4,3-d]pyrimidin-4-yl]-2-(isocyanomethyl)piperazin-1-yl]-4-methoxybut-2-en-1-one;1-[(2R)-4-[8-fluoro-7-(2-fluorophenyl)-2-[[(2S)-1-methylpyrrolidin-2-yl]methoxy]pyrido[4,3-d]pyrimidin-4-yl]-2-(isocyanomethyl)piperazin-1-yl]prop-2-en-1-one;2-fluoro-1-[(2R)-2-(isocyanomethyl)-4-[7-(8-methylnaphthalen-1-yl)-2-[[(2S)-1-methylpyrrolidin-2-yl]methoxy]-8-(2,2,2-trifluoroethoxy)pyrido[4,3-d]pyrimidin-4-yl]piperazin-1-yl]prop-2-en-1-one;(E)-1-[(2R)-4-[8-fluoro-7-(8-methylnaphthalen-1-yl)-2-[[(2S)-1-methylpyrrolidin-2-yl]methoxy]pyrido[4,3-d]pyrimidin-4-yl]-2-(isocyanomethyl)piperazin-1-yl]-4-methoxybut-2-en-1-one;sulfane
CID 157833979
6-[2-(5-Chloro-2,4-difluorophenyl)-3-pyridinyl]quinazolin-4-amine;6-[2-(2,4-difluorophenyl)-3-pyridinyl]quinazolin-4-amine;6-[2-(2,5-difluorophenyl)-3-pyridinyl]quinazolin-4-amine;6-[2-(3,4-difluorophenyl)-3-pyridinyl]quinazolin-4-amine;6-[2-(3-methoxyphenyl)-3-pyridinyl]quinazolin-4-amine;6-[2-[3-(trifluoromethoxy)phenyl]-3-pyridinyl]quinazolin-4-amine
CID 157867768
7-[2-(3-Chloro-4-fluorophenyl)-3-pyridinyl]quinazoline-2,4-diamine;6-[2-[3-(cyclopropylmethoxy)phenyl]-3-pyridinyl]quinazolin-4-amine;6-[2-[3-(2-methoxyethoxy)phenyl]-3-pyridinyl]quinazolin-4-amine;6-[2-(3-morpholin-4-ylphenyl)-3-pyridinyl]quinazolin-4-amine;6-[2-[3-(2,2,2-trifluoroethoxy)phenyl]-3-pyridinyl]quinazolin-4-amine
CID 158360308
1-[4-[[4-Chloro-3-(cyclopropylmethyl)-2-methoxyquinolin-6-yl]-hydroxy-phenylmethyl]piperidin-1-yl]ethanone;(4-chloro-2,3-dimethylquinolin-6-yl)-(3-chlorophenyl)-pyridin-3-ylmethanol;[4-chloro-2-methoxy-3-[[4-methyl-4-(trifluoromethyl)piperidin-1-yl]methyl]quinolin-6-yl]-(3-methylimidazol-4-yl)-[2-(trifluoromethyl)-4-pyridinyl]methanol;(4-chloro-3-methyl-2-pyridin-3-ylquinolin-6-yl)-(3-chlorophenyl)-pyridin-3-ylmethanol;(3-chlorophenyl)-(4-chloro-3-propan-2-yl-2-pyridin-3-ylquinolin-6-yl)-pyridin-3-ylmethanol
CID 158689185
6-[2-(5-Chloro-2,4-difluorophenyl)-3-pyridinyl]quinazolin-4-amine;6-[2-(5-chloro-2-fluorophenyl)-3-pyridinyl]quinazolin-4-amine;6-[2-(3,4-difluorophenyl)-3-pyridinyl]quinazolin-4-amine;6-[2-(3-methoxyphenyl)-3-pyridinyl]quinazolin-4-amine;6-[2-[3-(trifluoromethoxy)phenyl]-3-pyridinyl]quinazolin-4-amine
CID 159035946
7-[2-(3-Chloro-4-fluorophenyl)-3-pyridinyl]quinazoline-2,4-diamine;7-[2-(3-chlorophenyl)-3-pyridinyl]quinazoline-2,4-diamine;7-[2-(4-fluoro-3-methylphenyl)-3-pyridinyl]quinazoline-2,4-diamine;6-[2-(3-morpholin-4-ylphenyl)-3-pyridinyl]quinazolin-4-amine;6-[2-[3-(2,2,2-trifluoroethoxy)phenyl]-3-pyridinyl]quinazolin-4-amine
CID 159394529
Tert-butyl 4-[[4-chloro-3-phenyl-2-(trifluoromethyl)quinolin-6-yl]-hydroxy-pyridin-3-ylmethyl]piperidine-1-carboxylate;[2-chloro-4-(dimethylamino)-3-phenylquinolin-6-yl]-(3-methylimidazol-4-yl)-pyridin-2-ylmethanol;[4-chloro-2-(dimethylamino)-3-phenylquinolin-6-yl]-pyridin-2-yl-pyridin-4-ylmethanol;(3-chlorophenyl)-(2,4-dichloro-3-phenylquinolin-6-yl)-[2-(trifluoromethyl)-4-pyridinyl]methanol;(3-chlorophenyl)-(3-phenyl-2-propan-2-yloxyquinolin-6-yl)-pyridin-3-ylmethanol;(2,4-dichloro-3-phenylquinolin-6-yl)-(1-methylpiperidin-4-yl)-pyridin-3-ylmethanol
CID 160101837

Frequently Asked Questions

What is the IUPAC name of 3-[6-[2-(3-chloro-4-fluorophenyl)-3-pyridinyl]quinazolin-4-yl]oxy-N,N-dimethylpropan-1-amine;6-[2-(4-fluoro-3-methylphenyl)-3-pyridinyl]-4-[2-(4-methylpiperazin-1-yl)ethoxy]quinazoline;6-[2-(4-fluoro-3-methylphenyl)-3-pyridinyl]-4-[3-(4-methylpiperazin-1-yl)propoxy]quinazoline;6-[2-(4-fluoro-3-methylphenyl)-3-pyridinyl]-4-[(6-methyl-3-pyridinyl)oxy]quinazoline;1-[3-[6-[2-(4-fluoro-3-methylphenyl)-3-pyridinyl]quinazolin-4-yl]oxypropyl]pyrrolidin-2-one?
The IUPAC name of 3-[6-[2-(3-chloro-4-fluorophenyl)-3-pyridinyl]quinazolin-4-yl]oxy-N,N-dimethylpropan-1-amine;6-[2-(4-fluoro-3-methylphenyl)-3-pyridinyl]-4-[2-(4-methylpiperazin-1-yl)ethoxy]quinazoline;6-[2-(4-fluoro-3-methylphenyl)-3-pyridinyl]-4-[3-(4-methylpiperazin-1-yl)propoxy]quinazoline;6-[2-(4-fluoro-3-methylphenyl)-3-pyridinyl]-4-[(6-methyl-3-pyridinyl)oxy]quinazoline;1-[3-[6-[2-(4-fluoro-3-methylphenyl)-3-pyridinyl]quinazolin-4-yl]oxypropyl]pyrrolidin-2-one (CID 159621308) is 3-[6-[2-(3-chloro-4-fluorophenyl)-3-pyridinyl]quinazolin-4-yl]oxy-N,N-dimethylpropan-1-amine;6-[2-(4-fluoro-3-methylphenyl)-3-pyridinyl]-4-[2-(4-methylpiperazin-1-yl)ethoxy]quinazoline;6-[2-(4-fluoro-3-methylphenyl)-3-pyridinyl]-4-[3-(4-methylpiperazin-1-yl)propoxy]quinazoline;6-[2-(4-fluoro-3-methylphenyl)-3-pyridinyl]-4-[(6-methyl-3-pyridinyl)oxy]quinazoline;1-[3-[6-[2-(4-fluoro-3-methylphenyl)-3-pyridinyl]quinazolin-4-yl]oxypropyl]pyrrolidin-2-one.
What is the SMILES notation for 3-[6-[2-(3-chloro-4-fluorophenyl)-3-pyridinyl]quinazolin-4-yl]oxy-N,N-dimethylpropan-1-amine;6-[2-(4-fluoro-3-methylphenyl)-3-pyridinyl]-4-[2-(4-methylpiperazin-1-yl)ethoxy]quinazoline;6-[2-(4-fluoro-3-methylphenyl)-3-pyridinyl]-4-[3-(4-methylpiperazin-1-yl)propoxy]quinazoline;6-[2-(4-fluoro-3-methylphenyl)-3-pyridinyl]-4-[(6-methyl-3-pyridinyl)oxy]quinazoline;1-[3-[6-[2-(4-fluoro-3-methylphenyl)-3-pyridinyl]quinazolin-4-yl]oxypropyl]pyrrolidin-2-one?
The canonical SMILES for 3-[6-[2-(3-chloro-4-fluorophenyl)-3-pyridinyl]quinazolin-4-yl]oxy-N,N-dimethylpropan-1-amine;6-[2-(4-fluoro-3-methylphenyl)-3-pyridinyl]-4-[2-(4-methylpiperazin-1-yl)ethoxy]quinazoline;6-[2-(4-fluoro-3-methylphenyl)-3-pyridinyl]-4-[3-(4-methylpiperazin-1-yl)propoxy]quinazoline;6-[2-(4-fluoro-3-methylphenyl)-3-pyridinyl]-4-[(6-methyl-3-pyridinyl)oxy]quinazoline;1-[3-[6-[2-(4-fluoro-3-methylphenyl)-3-pyridinyl]quinazolin-4-yl]oxypropyl]pyrrolidin-2-one is CN(C)CCCOc1ncnc2ccc(-c3cccnc3-c3ccc(F)c(Cl)c3)cc12.Cc1cc(-c2ncccc2-c2ccc3ncnc(OCCCN4CCCC4=O)c3c2)ccc1F.Cc1cc(-c2ncccc2-c2ccc3ncnc(OCCCN4CCN(C)CC4)c3c2)ccc1F.Cc1cc(-c2ncccc2-c2ccc3ncnc(OCCN4CCN(C)CC4)c3c2)ccc1F.Cc1ccc(Oc2ncnc3ccc(-c4cccnc4-c4ccc(F)c(C)c4)cc23)cn1.
What is the InChIKey of 3-[6-[2-(3-chloro-4-fluorophenyl)-3-pyridinyl]quinazolin-4-yl]oxy-N,N-dimethylpropan-1-amine;6-[2-(4-fluoro-3-methylphenyl)-3-pyridinyl]-4-[2-(4-methylpiperazin-1-yl)ethoxy]quinazoline;6-[2-(4-fluoro-3-methylphenyl)-3-pyridinyl]-4-[3-(4-methylpiperazin-1-yl)propoxy]quinazoline;6-[2-(4-fluoro-3-methylphenyl)-3-pyridinyl]-4-[(6-methyl-3-pyridinyl)oxy]quinazoline;1-[3-[6-[2-(4-fluoro-3-methylphenyl)-3-pyridinyl]quinazolin-4-yl]oxypropyl]pyrrolidin-2-one?
The InChIKey is MNXOVOBNNBZDBF-UHFFFAOYSA-N. The full InChI is InChI=1S/C28H30FN5O.C27H28FN5O.C27H25FN4O2.C26H19FN4O.C24H22ClFN4O/c1-20-17-22(6-8-25(20)29)27-23(5-3-10-30-27)21-7-9-26-24(18-21)28(32-19-31-26)35-16-4-11-34-14-12-33(2)13-15-34;1-19-16-21(5-7-24(19)28)26-22(4-3-9-29-26)20-6-8-25-23(17-20)27(31-18-30-25)34-15-14-33-12-10-32(2)11-13-33;1-18-15-20(7-9-23(18)28)26-21(5-2-11-29-26)19-8-10-24-22(16-19)27(31-17-30-24)34-14-4-13-32-12-3-6-25(32)33;1-16-12-19(6-9-23(16)27)25-21(4-3-11-28-25)18-7-10-24-22(13-18)26(31-15-30-24)32-20-8-5-17(2)29-14-20;1-30(2)11-4-12-31-24-19-13-16(7-9-22(19)28-15-29-24)18-5-3-10-27-23(18)17-6-8-21(26)20(25)14-17/h3,5-10,17-19H,4,11-16H2,1-2H3;3-9,16-18H,10-15H2,1-2H3;2,5,7-11,15-17H,3-4,6,12-14H2,1H3;3-15H,1-2H3;3,5-10,13-15H,4,11-12H2,1-2H3.
What are the key properties of 3-[6-[2-(3-chloro-4-fluorophenyl)-3-pyridinyl]quinazolin-4-yl]oxy-N,N-dimethylpropan-1-amine;6-[2-(4-fluoro-3-methylphenyl)-3-pyridinyl]-4-[2-(4-methylpiperazin-1-yl)ethoxy]quinazoline;6-[2-(4-fluoro-3-methylphenyl)-3-pyridinyl]-4-[3-(4-methylpiperazin-1-yl)propoxy]quinazoline;6-[2-(4-fluoro-3-methylphenyl)-3-pyridinyl]-4-[(6-methyl-3-pyridinyl)oxy]quinazoline;1-[3-[6-[2-(4-fluoro-3-methylphenyl)-3-pyridinyl]quinazolin-4-yl]oxypropyl]pyrrolidin-2-one?
3-[6-[2-(3-chloro-4-fluorophenyl)-3-pyridinyl]quinazolin-4-yl]oxy-N,N-dimethylpropan-1-amine;6-[2-(4-fluoro-3-methylphenyl)-3-pyridinyl]-4-[2-(4-methylpiperazin-1-yl)ethoxy]quinazoline;6-[2-(4-fluoro-3-methylphenyl)-3-pyridinyl]-4-[3-(4-methylpiperazin-1-yl)propoxy]quinazoline;6-[2-(4-fluoro-3-methylphenyl)-3-pyridinyl]-4-[(6-methyl-3-pyridinyl)oxy]quinazoline;1-[3-[6-[2-(4-fluoro-3-methylphenyl)-3-pyridinyl]quinazolin-4-yl]oxypropyl]pyrrolidin-2-one has a molecular weight of 2245.03 g/mol, XLogP of 26.24, 31 rotatable bonds, 0 hydrogen bond donors, and 27 hydrogen bond acceptors.
Where does this data come from?
All data for 3-[6-[2-(3-chloro-4-fluorophenyl)-3-pyridinyl]quinazolin-4-yl]oxy-N,N-dimethylpropan-1-amine;6-[2-(4-fluoro-3-methylphenyl)-3-pyridinyl]-4-[2-(4-methylpiperazin-1-yl)ethoxy]quinazoline;6-[2-(4-fluoro-3-methylphenyl)-3-pyridinyl]-4-[3-(4-methylpiperazin-1-yl)propoxy]quinazoline;6-[2-(4-fluoro-3-methylphenyl)-3-pyridinyl]-4-[(6-methyl-3-pyridinyl)oxy]quinazoline;1-[3-[6-[2-(4-fluoro-3-methylphenyl)-3-pyridinyl]quinazolin-4-yl]oxypropyl]pyrrolidin-2-one is sourced from PubChem (CID 159621308), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).