N-cyclopropyl-N-[5-(1-cyclopropyl-2,6-dioxo-3-propyl-7H-purin-8-yl)-2-pyridinyl]pyridine-3-carboxamide;N-[5-(1-cyclopropyl-2,6-dioxo-3-propyl-7H-purin-8-yl)-2-pyridinyl]-N-(cyclopropylmethyl)-6-(fluoromethyl)pyridine-3-carboxamide;N-[5-(1-cyclopropyl-2,6-dioxo-3-propyl-7H-purin-8-yl)-2-pyridinyl]-N-(cyclopropylmethyl)-6-(trifluoromethyl)pyridine-3-carboxamide;N-[5-(1-cyclopropyl-2,6-dioxo-3-propyl-7H-purin-8-yl)-2-pyridinyl]-N-ethylpyridine-3-carboxamide;N-[5-(1-cyclopropyl-2,6-dioxo-3-propyl-7H-purin-8-yl)-2-pyridinyl]-6-(fluoromethyl)-N-methylpyridine-3-carboxamide;N-[5-(1-cyclopropyl-2,6-dioxo-3-propyl-7H-purin-8-yl)-2-pyridinyl]-N-(oxolan-2-ylmethyl)-6-(trifluoromethyl)pyridine-3-carboxamide;N-[5-(1-cyclopropyl-2,6-dioxo-3-propyl-7H-purin-8-yl)-2-pyridinyl]-N-propylpyridine-3-carboxamide

C180H183F8N49O22 — CID 159621420

IUPACN-cyclopropyl-N-[5-(1-cyclopropyl-2,6-dioxo-3-propyl-7H-purin-8-yl)-2-pyridinyl]pyridine-3-carboxamide;N-[5-(1-cyclopropyl-2,6-dioxo-3-propyl-7H-purin-8-yl)-2-pyridinyl]-N-(cyclopropylmethyl)-6-(fluoromethyl)pyridine-3-carboxamide;N-[5-(1-cyclopropyl-2,6-dioxo-3-propyl-7H-purin-8-yl)-2-pyridinyl]-N-(cyclopropylmethyl)-6-(trifluoromethyl)pyridine-3-carboxamide;N-[5-(1-cyclopropyl-2,6-dioxo-3-propyl-7H-purin-8-yl)-2-pyridinyl]-N-ethylpyridine-3-carboxamide;N-[5-(1-cyclopropyl-2,6-dioxo-3-propyl-7H-purin-8-yl)-2-pyridinyl]-6-(fluoromethyl)-N-methylpyridine-3-carboxamide;N-[5-(1-cyclopropyl-2,6-dioxo-3-propyl-7H-purin-8-yl)-2-pyridinyl]-N-(oxolan-2-ylmethyl)-6-(trifluoromethyl)pyridine-3-carboxamide;N-[5-(1-cyclopropyl-2,6-dioxo-3-propyl-7H-purin-8-yl)-2-pyridinyl]-N-propylpyridine-3-carboxamide
SMILESCCCN(C(=O)c1cccnc1)c1ccc(-c2nc3c([nH]2)c(=O)n(C2CC2)c(=O)n3CCC)cn1.CCCn1c(=O)n(C2CC2)c(=O)c2[nH]c(-c3ccc(N(C(=O)c4cccnc4)C4CC4)nc3)nc21.CCCn1c(=O)n(C2CC2)c(=O)c2[nH]c(-c3ccc(N(C)C(=O)c4ccc(CF)nc4)nc3)nc21.CCCn1c(=O)n(C2CC2)c(=O)c2[nH]c(-c3ccc(N(CC)C(=O)c4cccnc4)nc3)nc21.CCCn1c(=O)n(C2CC2)c(=O)c2[nH]c(-c3ccc(N(CC4CC4)C(=O)c4ccc(C(F)(F)F)nc4)nc3)nc21.CCCn1c(=O)n(C2CC2)c(=O)c2[nH]c(-c3ccc(N(CC4CC4)C(=O)c4ccc(CF)nc4)nc3)nc21.CCCn1c(=O)n(C2CC2)c(=O)c2[nH]c(-c3ccc(N(CC4CCCO4)C(=O)c4ccc(C(F)(F)F)nc4)nc3)nc21
InChIInChI=1S/C28H28F3N7O4.C27H26F3N7O3.C27H28FN7O3.C25H25N7O3.C25H27N7O3.C24H24FN7O3.C24H25N7O3/c1-2-11-36-24-22(26(40)38(27(36)41)18-7-8-18)34-23(35-24)16-6-10-21(33-13-16)37(15-19-4-3-12-42-19)25(39)17-5-9-20(32-14-17)28(29,30)31;1-2-11-35-23-21(25(39)37(26(35)40)18-7-8-18)33-22(34-23)16-6-10-20(32-12-16)36(14-15-3-4-15)24(38)17-5-9-19(31-13-17)27(28,29)30;1-2-11-33-24-22(26(37)35(27(33)38)20-8-9-20)31-23(32-24)17-6-10-21(30-13-17)34(15-16-3-4-16)25(36)18-5-7-19(12-28)29-14-18;1-2-12-30-22-20(24(34)32(25(30)35)18-8-9-18)28-21(29-22)15-5-10-19(27-14-15)31(17-6-7-17)23(33)16-4-3-11-26-13-16;1-3-12-30(23(33)17-6-5-11-26-14-17)19-10-7-16(15-27-19)21-28-20-22(29-21)31(13-4-2)25(35)32(24(20)34)18-8-9-18;1-3-10-31-21-19(23(34)32(24(31)35)17-7-8-17)28-20(29-21)14-5-9-18(27-12-14)30(2)22(33)15-4-6-16(11-25)26-13-15;1-3-12-30-21-19(23(33)31(24(30)34)17-8-9-17)27-20(28-21)15-7-10-18(26-14-15)29(4-2)22(32)16-6-5-11-25-13-16/h5-6,9-10,13-14,18-19H,2-4,7-8,11-12,15H2,1H3,(H,34,35);5-6,9-10,12-13,15,18H,2-4,7-8,11,14H2,1H3,(H,33,34);5-7,10,13-14,16,20H,2-4,8-9,11-12,15H2,1H3,(H,31,32);3-5,10-11,13-14,17-18H,2,6-9,12H2,1H3,(H,28,29);5-7,10-11,14-15,18H,3-4,8-9,12-13H2,1-2H3,(H,28,29);4-6,9,12-13,17H,3,7-8,10-11H2,1-2H3,(H,28,29);5-7,10-11,13-14,17H,3-4,8-9,12H2,1-2H3,(H,27,28)
InChIKeyMNXXNQOALFCNOU-UHFFFAOYSA-N
MW3536.75 g/mol
LogP23.34
Rot. Bonds54

About N-cyclopropyl-N-[5-(1-cyclopropyl-2,6-dioxo-3-propyl-7H-purin-8-yl)-2-pyridinyl]pyridine-3-carboxamide;N-[5-(1-cyclopropyl-2,6-dioxo-3-propyl-7H-purin-8-yl)-2-pyridinyl]-N-(cyclopropylmethyl)-6-(fluoromethyl)pyridine-3-carboxamide;N-[5-(1-cyclopropyl-2,6-dioxo-3-propyl-7H-purin-8-yl)-2-pyridinyl]-N-(cyclopropylmethyl)-6-(trifluoromethyl)pyridine-3-carboxamide;N-[5-(1-cyclopropyl-2,6-dioxo-3-propyl-7H-purin-8-yl)-2-pyridinyl]-N-ethylpyridine-3-carboxamide;N-[5-(1-cyclopropyl-2,6-dioxo-3-propyl-7H-purin-8-yl)-2-pyridinyl]-6-(fluoromethyl)-N-methylpyridine-3-carboxamide;N-[5-(1-cyclopropyl-2,6-dioxo-3-propyl-7H-purin-8-yl)-2-pyridinyl]-N-(oxolan-2-ylmethyl)-6-(trifluoromethyl)pyridine-3-carboxamide;N-[5-(1-cyclopropyl-2,6-dioxo-3-propyl-7H-purin-8-yl)-2-pyridinyl]-N-propylpyridine-3-carboxamide

N-cyclopropyl-N-[5-(1-cyclopropyl-2,6-dioxo-3-propyl-7H-purin-8-yl)-2-pyridinyl]pyridine-3-carboxamide;N-[5-(1-cyclopropyl-2,6-dioxo-3-propyl-7H-purin-8-yl)-2-pyridinyl]-N-(cyclopropylmethyl)-6-(fluoromethyl)pyridine-3-carboxamide;N-[5-(1-cyclopropyl-2,6-dioxo-3-propyl-7H-purin-8-yl)-2-pyridinyl]-N-(cyclopropylmethyl)-6-(trifluoromethyl)pyridine-3-carboxamide;N-[5-(1-cyclopropyl-2,6-dioxo-3-propyl-7H-purin-8-yl)-2-pyridinyl]-N-ethylpyridine-3-carboxamide;N-[5-(1-cyclopropyl-2,6-dioxo-3-propyl-7H-purin-8-yl)-2-pyridinyl]-6-(fluoromethyl)-N-methylpyridine-3-carboxamide;N-[5-(1-cyclopropyl-2,6-dioxo-3-propyl-7H-purin-8-yl)-2-pyridinyl]-N-(oxolan-2-ylmethyl)-6-(trifluoromethyl)pyridine-3-carboxamide;N-[5-(1-cyclopropyl-2,6-dioxo-3-propyl-7H-purin-8-yl)-2-pyridinyl]-N-propylpyridine-3-carboxamide (PubChem CID 159621420) has the molecular formula C180H183F8N49O22 and a molecular weight of 3536.75 g/mol. Its IUPAC name is N-cyclopropyl-N-[5-(1-cyclopropyl-2,6-dioxo-3-propyl-7H-purin-8-yl)-2-pyridinyl]pyridine-3-carboxamide;N-[5-(1-cyclopropyl-2,6-dioxo-3-propyl-7H-purin-8-yl)-2-pyridinyl]-N-(cyclopropylmethyl)-6-(fluoromethyl)pyridine-3-carboxamide;N-[5-(1-cyclopropyl-2,6-dioxo-3-propyl-7H-purin-8-yl)-2-pyridinyl]-N-(cyclopropylmethyl)-6-(trifluoromethyl)pyridine-3-carboxamide;N-[5-(1-cyclopropyl-2,6-dioxo-3-propyl-7H-purin-8-yl)-2-pyridinyl]-N-ethylpyridine-3-carboxamide;N-[5-(1-cyclopropyl-2,6-dioxo-3-propyl-7H-purin-8-yl)-2-pyridinyl]-6-(fluoromethyl)-N-methylpyridine-3-carboxamide;N-[5-(1-cyclopropyl-2,6-dioxo-3-propyl-7H-purin-8-yl)-2-pyridinyl]-N-(oxolan-2-ylmethyl)-6-(trifluoromethyl)pyridine-3-carboxamide;N-[5-(1-cyclopropyl-2,6-dioxo-3-propyl-7H-purin-8-yl)-2-pyridinyl]-N-propylpyridine-3-carboxamide.

Molecular Properties

Compound NameN-cyclopropyl-N-[5-(1-cyclopropyl-2,6-dioxo-3-propyl-7H-purin-8-yl)-2-pyridinyl]pyridine-3-carboxamide;N-[5-(1-cyclopropyl-2,6-dioxo-3-propyl-7H-purin-8-yl)-2-pyridinyl]-N-(cyclopropylmethyl)-6-(fluoromethyl)pyridine-3-carboxamide;N-[5-(1-cyclopropyl-2,6-dioxo-3-propyl-7H-purin-8-yl)-2-pyridinyl]-N-(cyclopropylmethyl)-6-(trifluoromethyl)pyridine-3-carboxamide;N-[5-(1-cyclopropyl-2,6-dioxo-3-propyl-7H-purin-8-yl)-2-pyridinyl]-N-ethylpyridine-3-carboxamide;N-[5-(1-cyclopropyl-2,6-dioxo-3-propyl-7H-purin-8-yl)-2-pyridinyl]-6-(fluoromethyl)-N-methylpyridine-3-carboxamide;N-[5-(1-cyclopropyl-2,6-dioxo-3-propyl-7H-purin-8-yl)-2-pyridinyl]-N-(oxolan-2-ylmethyl)-6-(trifluoromethyl)pyridine-3-carboxamide;N-[5-(1-cyclopropyl-2,6-dioxo-3-propyl-7H-purin-8-yl)-2-pyridinyl]-N-propylpyridine-3-carboxamide
PubChem CID159621420
Molecular FormulaC180H183F8N49O22
Molecular Weight3536.75 g/mol
Exact Mass3534.46
IUPAC NameN-cyclopropyl-N-[5-(1-cyclopropyl-2,6-dioxo-3-propyl-7H-purin-8-yl)-2-pyridinyl]pyridine-3-carboxamide;N-[5-(1-cyclopropyl-2,6-dioxo-3-propyl-7H-purin-8-yl)-2-pyridinyl]-N-(cyclopropylmethyl)-6-(fluoromethyl)pyridine-3-carboxamide;N-[5-(1-cyclopropyl-2,6-dioxo-3-propyl-7H-purin-8-yl)-2-pyridinyl]-N-(cyclopropylmethyl)-6-(trifluoromethyl)pyridine-3-carboxamide;N-[5-(1-cyclopropyl-2,6-dioxo-3-propyl-7H-purin-8-yl)-2-pyridinyl]-N-ethylpyridine-3-carboxamide;N-[5-(1-cyclopropyl-2,6-dioxo-3-propyl-7H-purin-8-yl)-2-pyridinyl]-6-(fluoromethyl)-N-methylpyridine-3-carboxamide;N-[5-(1-cyclopropyl-2,6-dioxo-3-propyl-7H-purin-8-yl)-2-pyridinyl]-N-(oxolan-2-ylmethyl)-6-(trifluoromethyl)pyridine-3-carboxamide;N-[5-(1-cyclopropyl-2,6-dioxo-3-propyl-7H-purin-8-yl)-2-pyridinyl]-N-propylpyridine-3-carboxamide
SMILESCCCN(C(=O)c1cccnc1)c1ccc(-c2nc3c([nH]2)c(=O)n(C2CC2)c(=O)n3CCC)cn1.CCCn1c(=O)n(C2CC2)c(=O)c2[nH]c(-c3ccc(N(C(=O)c4cccnc4)C4CC4)nc3)nc21.CCCn1c(=O)n(C2CC2)c(=O)c2[nH]c(-c3ccc(N(C)C(=O)c4ccc(CF)nc4)nc3)nc21.CCCn1c(=O)n(C2CC2)c(=O)c2[nH]c(-c3ccc(N(CC)C(=O)c4cccnc4)nc3)nc21.CCCn1c(=O)n(C2CC2)c(=O)c2[nH]c(-c3ccc(N(CC4CC4)C(=O)c4ccc(C(F)(F)F)nc4)nc3)nc21.CCCn1c(=O)n(C2CC2)c(=O)c2[nH]c(-c3ccc(N(CC4CC4)C(=O)c4ccc(CF)nc4)nc3)nc21.CCCn1c(=O)n(C2CC2)c(=O)c2[nH]c(-c3ccc(N(CC4CCCO4)C(=O)c4ccc(C(F)(F)F)nc4)nc3)nc21
InChIInChI=1S/C28H28F3N7O4.C27H26F3N7O3.C27H28FN7O3.C25H25N7O3.C25H27N7O3.C24H24FN7O3.C24H25N7O3/c1-2-11-36-24-22(26(40)38(27(36)41)18-7-8-18)34-23(35-24)16-6-10-21(33-13-16)37(15-19-4-3-12-42-19)25(39)17-5-9-20(32-14-17)28(29,30)31;1-2-11-35-23-21(25(39)37(26(35)40)18-7-8-18)33-22(34-23)16-6-10-20(32-12-16)36(14-15-3-4-15)24(38)17-5-9-19(31-13-17)27(28,29)30;1-2-11-33-24-22(26(37)35(27(33)38)20-8-9-20)31-23(32-24)17-6-10-21(30-13-17)34(15-16-3-4-16)25(36)18-5-7-19(12-28)29-14-18;1-2-12-30-22-20(24(34)32(25(30)35)18-8-9-18)28-21(29-22)15-5-10-19(27-14-15)31(17-6-7-17)23(33)16-4-3-11-26-13-16;1-3-12-30(23(33)17-6-5-11-26-14-17)19-10-7-16(15-27-19)21-28-20-22(29-21)31(13-4-2)25(35)32(24(20)34)18-8-9-18;1-3-10-31-21-19(23(34)32(24(31)35)17-7-8-17)28-20(29-21)14-5-9-18(27-12-14)30(2)22(33)15-4-6-16(11-25)26-13-15;1-3-12-30-21-19(23(33)31(24(30)34)17-8-9-17)27-20(28-21)15-7-10-18(26-14-15)29(4-2)22(32)16-6-5-11-25-13-16/h5-6,9-10,13-14,18-19H,2-4,7-8,11-12,15H2,1H3,(H,34,35);5-6,9-10,12-13,15,18H,2-4,7-8,11,14H2,1H3,(H,33,34);5-7,10,13-14,16,20H,2-4,8-9,11-12,15H2,1H3,(H,31,32);3-5,10-11,13-14,17-18H,2,6-9,12H2,1H3,(H,28,29);5-7,10-11,14-15,18H,3-4,8-9,12-13H2,1-2H3,(H,28,29);4-6,9,12-13,17H,3,7-8,10-11H2,1-2H3,(H,28,29);5-7,10-11,13-14,17H,3-4,8-9,12H2,1-2H3,(H,27,28)
InChIKeyMNXXNQOALFCNOU-UHFFFAOYSA-N
XLogP23.34
TPSA840.62 Ų
H-Bond Donors7
H-Bond Acceptors57
Rotatable Bonds54
Heavy Atoms259
Complexity—

Lipinski Rule of Five

4 violations

RuleValue
MW ≤ 5003536.75
LogP ≤ 523.34
H-Bond Donors ≤ 57
H-Bond Acceptors ≤ 1057

Analyze N-cyclopropyl-N-[5-(1-cyclopropyl-2,6-dioxo-3-propyl-7H-purin-8-yl)-2-pyridinyl]pyridine-3-carboxamide;N-[5-(1-cyclopropyl-2,6-dioxo-3-propyl-7H-purin-8-yl)-2-pyridinyl]-N-(cyclopropylmethyl)-6-(fluoromethyl)pyridine-3-carboxamide;N-[5-(1-cyclopropyl-2,6-dioxo-3-propyl-7H-purin-8-yl)-2-pyridinyl]-N-(cyclopropylmethyl)-6-(trifluoromethyl)pyridine-3-carboxamide;N-[5-(1-cyclopropyl-2,6-dioxo-3-propyl-7H-purin-8-yl)-2-pyridinyl]-N-ethylpyridine-3-carboxamide;N-[5-(1-cyclopropyl-2,6-dioxo-3-propyl-7H-purin-8-yl)-2-pyridinyl]-6-(fluoromethyl)-N-methylpyridine-3-carboxamide;N-[5-(1-cyclopropyl-2,6-dioxo-3-propyl-7H-purin-8-yl)-2-pyridinyl]-N-(oxolan-2-ylmethyl)-6-(trifluoromethyl)pyridine-3-carboxamide;N-[5-(1-cyclopropyl-2,6-dioxo-3-propyl-7H-purin-8-yl)-2-pyridinyl]-N-propylpyridine-3-carboxamide with MolForge

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Related Compounds

N-[5-(1-cyclopropyl-2,6-dioxo-3-propyl-7H-purin-8-yl)pyridin-2-yl]-N-(oxolan-2-ylmethyl)-6-(trifluoromethyl)pyridine-3-carboxamide
CID 24780664
N-[5-(1-cyclopropyl-2,6-dioxo-3-propyl-7H-purin-8-yl)pyridin-2-yl]-N-(2-morpholin-4-ylethyl)-6-(trifluoromethyl)pyridine-3-carboxamide
CID 24780960
N-[5-(1-cyclopropyl-2,6-dioxo-3-propyl-7H-purin-8-yl)pyridin-2-yl]-N-(3-morpholin-4-ylpropyl)-6-(trifluoromethyl)pyridine-3-carboxamide
CID 42641948
N-[5-(1-cyclopropyl-2,6-dioxo-3-propyl-7H-purin-8-yl)-2-pyridinyl]-N-(oxolan-3-ylmethyl)-6-(trifluoromethyl)pyridine-3-carboxamide
CID 70793850
7-but-2-ynyl-2-(diethylamino)-1-methyl-8-piperidin-1-ylpurin-6-one;(2S)-1-(7-but-2-ynyl-1-methyl-6-oxo-8-piperidin-1-ylpurin-2-yl)pyrrolidine-2-carboxylic acid;7-but-2-ynyl-1-methyl-8-piperidin-1-yl-2-(pyridin-2-ylmethylamino)purin-6-one;ethyl 1-(7-but-2-ynyl-1-methyl-6-oxo-8-piperidin-1-ylpurin-2-yl)piperidine-2-carboxylate;tetrakis(2,2,2-trifluoroacetic acid)
CID 157111726
N-[5-(1-cyclopropyl-2,6-dioxo-3-propyl-7H-purin-8-yl)-2-pyridinyl]-6-fluoro-N-(2-piperidin-1-ylethyl)pyridine-3-carboxamide;N-[5-(1-cyclopropyl-2,6-dioxo-3-propyl-7H-purin-8-yl)-2-pyridinyl]-N-(2-morpholin-4-ylethyl)pyridine-3-carboxamide;N-[5-(1-cyclopropyl-2,6-dioxo-3-propyl-7H-purin-8-yl)-2-pyridinyl]-N-(2-morpholin-4-ylethyl)-6-(trifluoromethyl)pyridine-3-carboxamide;N-[5-(1-cyclopropyl-2,6-dioxo-3-propyl-7H-purin-8-yl)-2-pyridinyl]-N-(2-piperidin-1-ylethyl)pyridine-3-carboxamide;N-[5-(1-cyclopropyl-2,6-dioxo-3-propyl-7H-purin-8-yl)-2-pyridinyl]-N-(2-piperidin-1-ylethyl)-6-(trifluoromethyl)pyridine-3-carboxamide;N-[5-(1-cyclopropyl-2,6-dioxo-3-propyl-7H-purin-8-yl)-2-pyridinyl]-N-prop-2-enyl-6-(trifluoromethyl)pyridine-3-carboxamide
CID 157298021
N-[5-(1-cyclopropyl-2,6-dioxo-3-propyl-7H-purin-8-yl)-2-pyridinyl]-N-(cyclopropylmethyl)-6-fluoropyridine-3-carboxamide;N-[5-(1-cyclopropyl-2,6-dioxo-3-propyl-7H-purin-8-yl)-2-pyridinyl]-6-fluoro-N-methylpyridine-3-carboxamide;N-[5-(1-cyclopropyl-2,6-dioxo-3-propyl-7H-purin-8-yl)-2-pyridinyl]-6-methyl-N-(2-piperidin-1-ylethyl)pyridine-3-carboxamide;N-[5-(1-cyclopropyl-2,6-dioxo-3-propyl-7H-purin-8-yl)-2-pyridinyl]-N-(2-piperidin-1-ylethyl)pyridine-3-carboxamide;N-[5-(1-cyclopropyl-2,6-dioxo-3-propyl-7H-purin-8-yl)-2-pyridinyl]-N-prop-2-enylpyridine-3-carboxamide;N-[5-(1-cyclopropyl-2,6-dioxo-3-propyl-7H-purin-8-yl)-2-pyridinyl]-N-prop-2-enyl-6-(trifluoromethyl)pyridine-3-carboxamide
CID 157382997
N-[5-(1-cyclopropyl-2,6-dioxo-3-propyl-7H-purin-8-yl)-2-pyridinyl]-N-(2-morpholin-4-ylethyl)pyridine-3-carboxamide;N-[5-(1-cyclopropyl-2,6-dioxo-3-propyl-7H-purin-8-yl)-2-pyridinyl]-N-(2-morpholin-4-ylethyl)-6-(trifluoromethyl)pyridine-3-carboxamide;N-[5-(1-cyclopropyl-2,6-dioxo-3-propyl-7H-purin-8-yl)-2-pyridinyl]-N-(2-piperidin-1-ylethyl)pyridine-3-carboxamide;N-[5-(1-cyclopropyl-2,6-dioxo-3-propyl-7H-purin-8-yl)-2-pyridinyl]-N-(2-piperidin-1-ylethyl)-6-(trifluoromethyl)pyridine-3-carboxamide
CID 157511719
6-chloro-N-[5-(1-cyclopropyl-2,6-dioxo-3-propyl-7H-purin-8-yl)-2-pyridinyl]-N-(2-pyridin-2-ylethyl)pyridine-3-carboxamide;N-[5-(1-cyclopropyl-2,6-dioxo-3-propyl-7H-purin-8-yl)-2-pyridinyl]-N-(cyclopropylmethyl)-3,4-difluorobenzamide;N-[5-(1-cyclopropyl-2,6-dioxo-3-propyl-7H-purin-8-yl)-2-pyridinyl]-N-(cyclopropylmethyl)-4-fluorobenzamide;N-[5-(1-cyclopropyl-2,6-dioxo-3-propyl-7H-purin-8-yl)-2-pyridinyl]-2,2-dimethyl-N-[[6-(trifluoromethyl)-3-pyridinyl]methyl]propanamide;N-[5-(1-cyclopropyl-2,6-dioxo-3-propyl-7H-purin-8-yl)-2-pyridinyl]-N-(3-morpholin-4-ylpropyl)benzamide;N-[5-(1-cyclopropyl-2,6-dioxo-3-propyl-7H-purin-8-yl)-2-pyridinyl]-N-(3-morpholin-4-ylpropyl)-6-(trifluoromethyl)pyridine-3-carboxamide
CID 157534381
N-[5-(1-cyclopropyl-2,6-dioxo-3-propyl-7H-purin-8-yl)-2-pyridinyl]-N-(2-methylpropyl)-6-(trifluoromethyl)pyridine-3-carboxamide;N-[5-(1-cyclopropyl-2,6-dioxo-3-propyl-7H-purin-8-yl)-2-pyridinyl]-N-(2-pyrrolidin-1-ylethyl)pyridine-3-carboxamide;N-[5-(1-cyclopropyl-2,6-dioxo-3-propyl-7H-purin-8-yl)-2-pyridinyl]-N-(2-pyrrolidin-1-ylethyl)-6-(trifluoromethyl)pyridine-3-carboxamide;N-[5-(1-cyclopropyl-2,6-dioxo-3-propyl-7H-purin-8-yl)-2-pyridinyl]-N-(thiophen-2-ylmethyl)pyridine-3-carboxamide;N-(cyclopropylmethyl)-N-[5-(2,6-dioxo-1,3-dipropyl-7H-purin-8-yl)-2-pyridinyl]pyridine-3-carboxamide
CID 157554537
N-[5-(1-cyclopropyl-2,6-dioxo-3-propyl-7H-purin-8-yl)-2-pyridinyl]-N-(2-methylpropyl)-6-(trifluoromethyl)pyridine-3-carboxamide;N-[5-(1-cyclopropyl-2,6-dioxo-3-propyl-7H-purin-8-yl)-2-pyridinyl]-N-(thiophen-2-ylmethyl)pyridine-3-carboxamide;N-(cyclopropylmethyl)-N-[5-(2,6-dioxo-1,3-dipropyl-7H-purin-8-yl)-2-pyridinyl]pyridine-3-carboxamide;N-(cyclopropylmethyl)-N-[5-(2,6-dioxo-1,3-dipropyl-7H-purin-8-yl)-2-pyridinyl]-6-(trifluoromethyl)pyridine-3-carboxamide
CID 158007206
N-[5-(1-cyclopropyl-2,6-dioxo-3-propyl-7H-purin-8-yl)-2-pyridinyl]-N-(cyclopropylmethyl)-6-fluoropyridine-3-carboxamide;N-[5-(1-cyclopropyl-2,6-dioxo-3-propyl-7H-purin-8-yl)-2-pyridinyl]-6-fluoro-N-methylpyridine-3-carboxamide;N-[5-(1-cyclopropyl-2,6-dioxo-3-propyl-7H-purin-8-yl)-2-pyridinyl]-N-prop-2-enylpyridine-3-carboxamide;N-[5-(1-cyclopropyl-2,6-dioxo-3-propyl-7H-purin-8-yl)-2-pyridinyl]-N-prop-2-enyl-6-(trifluoromethyl)pyridine-3-carboxamide
CID 158030026

Frequently Asked Questions

What is the IUPAC name of N-cyclopropyl-N-[5-(1-cyclopropyl-2,6-dioxo-3-propyl-7H-purin-8-yl)-2-pyridinyl]pyridine-3-carboxamide;N-[5-(1-cyclopropyl-2,6-dioxo-3-propyl-7H-purin-8-yl)-2-pyridinyl]-N-(cyclopropylmethyl)-6-(fluoromethyl)pyridine-3-carboxamide;N-[5-(1-cyclopropyl-2,6-dioxo-3-propyl-7H-purin-8-yl)-2-pyridinyl]-N-(cyclopropylmethyl)-6-(trifluoromethyl)pyridine-3-carboxamide;N-[5-(1-cyclopropyl-2,6-dioxo-3-propyl-7H-purin-8-yl)-2-pyridinyl]-N-ethylpyridine-3-carboxamide;N-[5-(1-cyclopropyl-2,6-dioxo-3-propyl-7H-purin-8-yl)-2-pyridinyl]-6-(fluoromethyl)-N-methylpyridine-3-carboxamide;N-[5-(1-cyclopropyl-2,6-dioxo-3-propyl-7H-purin-8-yl)-2-pyridinyl]-N-(oxolan-2-ylmethyl)-6-(trifluoromethyl)pyridine-3-carboxamide;N-[5-(1-cyclopropyl-2,6-dioxo-3-propyl-7H-purin-8-yl)-2-pyridinyl]-N-propylpyridine-3-carboxamide?
The IUPAC name of N-cyclopropyl-N-[5-(1-cyclopropyl-2,6-dioxo-3-propyl-7H-purin-8-yl)-2-pyridinyl]pyridine-3-carboxamide;N-[5-(1-cyclopropyl-2,6-dioxo-3-propyl-7H-purin-8-yl)-2-pyridinyl]-N-(cyclopropylmethyl)-6-(fluoromethyl)pyridine-3-carboxamide;N-[5-(1-cyclopropyl-2,6-dioxo-3-propyl-7H-purin-8-yl)-2-pyridinyl]-N-(cyclopropylmethyl)-6-(trifluoromethyl)pyridine-3-carboxamide;N-[5-(1-cyclopropyl-2,6-dioxo-3-propyl-7H-purin-8-yl)-2-pyridinyl]-N-ethylpyridine-3-carboxamide;N-[5-(1-cyclopropyl-2,6-dioxo-3-propyl-7H-purin-8-yl)-2-pyridinyl]-6-(fluoromethyl)-N-methylpyridine-3-carboxamide;N-[5-(1-cyclopropyl-2,6-dioxo-3-propyl-7H-purin-8-yl)-2-pyridinyl]-N-(oxolan-2-ylmethyl)-6-(trifluoromethyl)pyridine-3-carboxamide;N-[5-(1-cyclopropyl-2,6-dioxo-3-propyl-7H-purin-8-yl)-2-pyridinyl]-N-propylpyridine-3-carboxamide (CID 159621420) is N-cyclopropyl-N-[5-(1-cyclopropyl-2,6-dioxo-3-propyl-7H-purin-8-yl)-2-pyridinyl]pyridine-3-carboxamide;N-[5-(1-cyclopropyl-2,6-dioxo-3-propyl-7H-purin-8-yl)-2-pyridinyl]-N-(cyclopropylmethyl)-6-(fluoromethyl)pyridine-3-carboxamide;N-[5-(1-cyclopropyl-2,6-dioxo-3-propyl-7H-purin-8-yl)-2-pyridinyl]-N-(cyclopropylmethyl)-6-(trifluoromethyl)pyridine-3-carboxamide;N-[5-(1-cyclopropyl-2,6-dioxo-3-propyl-7H-purin-8-yl)-2-pyridinyl]-N-ethylpyridine-3-carboxamide;N-[5-(1-cyclopropyl-2,6-dioxo-3-propyl-7H-purin-8-yl)-2-pyridinyl]-6-(fluoromethyl)-N-methylpyridine-3-carboxamide;N-[5-(1-cyclopropyl-2,6-dioxo-3-propyl-7H-purin-8-yl)-2-pyridinyl]-N-(oxolan-2-ylmethyl)-6-(trifluoromethyl)pyridine-3-carboxamide;N-[5-(1-cyclopropyl-2,6-dioxo-3-propyl-7H-purin-8-yl)-2-pyridinyl]-N-propylpyridine-3-carboxamide.
What is the SMILES notation for N-cyclopropyl-N-[5-(1-cyclopropyl-2,6-dioxo-3-propyl-7H-purin-8-yl)-2-pyridinyl]pyridine-3-carboxamide;N-[5-(1-cyclopropyl-2,6-dioxo-3-propyl-7H-purin-8-yl)-2-pyridinyl]-N-(cyclopropylmethyl)-6-(fluoromethyl)pyridine-3-carboxamide;N-[5-(1-cyclopropyl-2,6-dioxo-3-propyl-7H-purin-8-yl)-2-pyridinyl]-N-(cyclopropylmethyl)-6-(trifluoromethyl)pyridine-3-carboxamide;N-[5-(1-cyclopropyl-2,6-dioxo-3-propyl-7H-purin-8-yl)-2-pyridinyl]-N-ethylpyridine-3-carboxamide;N-[5-(1-cyclopropyl-2,6-dioxo-3-propyl-7H-purin-8-yl)-2-pyridinyl]-6-(fluoromethyl)-N-methylpyridine-3-carboxamide;N-[5-(1-cyclopropyl-2,6-dioxo-3-propyl-7H-purin-8-yl)-2-pyridinyl]-N-(oxolan-2-ylmethyl)-6-(trifluoromethyl)pyridine-3-carboxamide;N-[5-(1-cyclopropyl-2,6-dioxo-3-propyl-7H-purin-8-yl)-2-pyridinyl]-N-propylpyridine-3-carboxamide?
The canonical SMILES for N-cyclopropyl-N-[5-(1-cyclopropyl-2,6-dioxo-3-propyl-7H-purin-8-yl)-2-pyridinyl]pyridine-3-carboxamide;N-[5-(1-cyclopropyl-2,6-dioxo-3-propyl-7H-purin-8-yl)-2-pyridinyl]-N-(cyclopropylmethyl)-6-(fluoromethyl)pyridine-3-carboxamide;N-[5-(1-cyclopropyl-2,6-dioxo-3-propyl-7H-purin-8-yl)-2-pyridinyl]-N-(cyclopropylmethyl)-6-(trifluoromethyl)pyridine-3-carboxamide;N-[5-(1-cyclopropyl-2,6-dioxo-3-propyl-7H-purin-8-yl)-2-pyridinyl]-N-ethylpyridine-3-carboxamide;N-[5-(1-cyclopropyl-2,6-dioxo-3-propyl-7H-purin-8-yl)-2-pyridinyl]-6-(fluoromethyl)-N-methylpyridine-3-carboxamide;N-[5-(1-cyclopropyl-2,6-dioxo-3-propyl-7H-purin-8-yl)-2-pyridinyl]-N-(oxolan-2-ylmethyl)-6-(trifluoromethyl)pyridine-3-carboxamide;N-[5-(1-cyclopropyl-2,6-dioxo-3-propyl-7H-purin-8-yl)-2-pyridinyl]-N-propylpyridine-3-carboxamide is CCCN(C(=O)c1cccnc1)c1ccc(-c2nc3c([nH]2)c(=O)n(C2CC2)c(=O)n3CCC)cn1.CCCn1c(=O)n(C2CC2)c(=O)c2[nH]c(-c3ccc(N(C(=O)c4cccnc4)C4CC4)nc3)nc21.CCCn1c(=O)n(C2CC2)c(=O)c2[nH]c(-c3ccc(N(C)C(=O)c4ccc(CF)nc4)nc3)nc21.CCCn1c(=O)n(C2CC2)c(=O)c2[nH]c(-c3ccc(N(CC)C(=O)c4cccnc4)nc3)nc21.CCCn1c(=O)n(C2CC2)c(=O)c2[nH]c(-c3ccc(N(CC4CC4)C(=O)c4ccc(C(F)(F)F)nc4)nc3)nc21.CCCn1c(=O)n(C2CC2)c(=O)c2[nH]c(-c3ccc(N(CC4CC4)C(=O)c4ccc(CF)nc4)nc3)nc21.CCCn1c(=O)n(C2CC2)c(=O)c2[nH]c(-c3ccc(N(CC4CCCO4)C(=O)c4ccc(C(F)(F)F)nc4)nc3)nc21.
What is the InChIKey of N-cyclopropyl-N-[5-(1-cyclopropyl-2,6-dioxo-3-propyl-7H-purin-8-yl)-2-pyridinyl]pyridine-3-carboxamide;N-[5-(1-cyclopropyl-2,6-dioxo-3-propyl-7H-purin-8-yl)-2-pyridinyl]-N-(cyclopropylmethyl)-6-(fluoromethyl)pyridine-3-carboxamide;N-[5-(1-cyclopropyl-2,6-dioxo-3-propyl-7H-purin-8-yl)-2-pyridinyl]-N-(cyclopropylmethyl)-6-(trifluoromethyl)pyridine-3-carboxamide;N-[5-(1-cyclopropyl-2,6-dioxo-3-propyl-7H-purin-8-yl)-2-pyridinyl]-N-ethylpyridine-3-carboxamide;N-[5-(1-cyclopropyl-2,6-dioxo-3-propyl-7H-purin-8-yl)-2-pyridinyl]-6-(fluoromethyl)-N-methylpyridine-3-carboxamide;N-[5-(1-cyclopropyl-2,6-dioxo-3-propyl-7H-purin-8-yl)-2-pyridinyl]-N-(oxolan-2-ylmethyl)-6-(trifluoromethyl)pyridine-3-carboxamide;N-[5-(1-cyclopropyl-2,6-dioxo-3-propyl-7H-purin-8-yl)-2-pyridinyl]-N-propylpyridine-3-carboxamide?
The InChIKey is MNXXNQOALFCNOU-UHFFFAOYSA-N. The full InChI is InChI=1S/C28H28F3N7O4.C27H26F3N7O3.C27H28FN7O3.C25H25N7O3.C25H27N7O3.C24H24FN7O3.C24H25N7O3/c1-2-11-36-24-22(26(40)38(27(36)41)18-7-8-18)34-23(35-24)16-6-10-21(33-13-16)37(15-19-4-3-12-42-19)25(39)17-5-9-20(32-14-17)28(29,30)31;1-2-11-35-23-21(25(39)37(26(35)40)18-7-8-18)33-22(34-23)16-6-10-20(32-12-16)36(14-15-3-4-15)24(38)17-5-9-19(31-13-17)27(28,29)30;1-2-11-33-24-22(26(37)35(27(33)38)20-8-9-20)31-23(32-24)17-6-10-21(30-13-17)34(15-16-3-4-16)25(36)18-5-7-19(12-28)29-14-18;1-2-12-30-22-20(24(34)32(25(30)35)18-8-9-18)28-21(29-22)15-5-10-19(27-14-15)31(17-6-7-17)23(33)16-4-3-11-26-13-16;1-3-12-30(23(33)17-6-5-11-26-14-17)19-10-7-16(15-27-19)21-28-20-22(29-21)31(13-4-2)25(35)32(24(20)34)18-8-9-18;1-3-10-31-21-19(23(34)32(24(31)35)17-7-8-17)28-20(29-21)14-5-9-18(27-12-14)30(2)22(33)15-4-6-16(11-25)26-13-15;1-3-12-30-21-19(23(33)31(24(30)34)17-8-9-17)27-20(28-21)15-7-10-18(26-14-15)29(4-2)22(32)16-6-5-11-25-13-16/h5-6,9-10,13-14,18-19H,2-4,7-8,11-12,15H2,1H3,(H,34,35);5-6,9-10,12-13,15,18H,2-4,7-8,11,14H2,1H3,(H,33,34);5-7,10,13-14,16,20H,2-4,8-9,11-12,15H2,1H3,(H,31,32);3-5,10-11,13-14,17-18H,2,6-9,12H2,1H3,(H,28,29);5-7,10-11,14-15,18H,3-4,8-9,12-13H2,1-2H3,(H,28,29);4-6,9,12-13,17H,3,7-8,10-11H2,1-2H3,(H,28,29);5-7,10-11,13-14,17H,3-4,8-9,12H2,1-2H3,(H,27,28).
What are the key properties of N-cyclopropyl-N-[5-(1-cyclopropyl-2,6-dioxo-3-propyl-7H-purin-8-yl)-2-pyridinyl]pyridine-3-carboxamide;N-[5-(1-cyclopropyl-2,6-dioxo-3-propyl-7H-purin-8-yl)-2-pyridinyl]-N-(cyclopropylmethyl)-6-(fluoromethyl)pyridine-3-carboxamide;N-[5-(1-cyclopropyl-2,6-dioxo-3-propyl-7H-purin-8-yl)-2-pyridinyl]-N-(cyclopropylmethyl)-6-(trifluoromethyl)pyridine-3-carboxamide;N-[5-(1-cyclopropyl-2,6-dioxo-3-propyl-7H-purin-8-yl)-2-pyridinyl]-N-ethylpyridine-3-carboxamide;N-[5-(1-cyclopropyl-2,6-dioxo-3-propyl-7H-purin-8-yl)-2-pyridinyl]-6-(fluoromethyl)-N-methylpyridine-3-carboxamide;N-[5-(1-cyclopropyl-2,6-dioxo-3-propyl-7H-purin-8-yl)-2-pyridinyl]-N-(oxolan-2-ylmethyl)-6-(trifluoromethyl)pyridine-3-carboxamide;N-[5-(1-cyclopropyl-2,6-dioxo-3-propyl-7H-purin-8-yl)-2-pyridinyl]-N-propylpyridine-3-carboxamide?
N-cyclopropyl-N-[5-(1-cyclopropyl-2,6-dioxo-3-propyl-7H-purin-8-yl)-2-pyridinyl]pyridine-3-carboxamide;N-[5-(1-cyclopropyl-2,6-dioxo-3-propyl-7H-purin-8-yl)-2-pyridinyl]-N-(cyclopropylmethyl)-6-(fluoromethyl)pyridine-3-carboxamide;N-[5-(1-cyclopropyl-2,6-dioxo-3-propyl-7H-purin-8-yl)-2-pyridinyl]-N-(cyclopropylmethyl)-6-(trifluoromethyl)pyridine-3-carboxamide;N-[5-(1-cyclopropyl-2,6-dioxo-3-propyl-7H-purin-8-yl)-2-pyridinyl]-N-ethylpyridine-3-carboxamide;N-[5-(1-cyclopropyl-2,6-dioxo-3-propyl-7H-purin-8-yl)-2-pyridinyl]-6-(fluoromethyl)-N-methylpyridine-3-carboxamide;N-[5-(1-cyclopropyl-2,6-dioxo-3-propyl-7H-purin-8-yl)-2-pyridinyl]-N-(oxolan-2-ylmethyl)-6-(trifluoromethyl)pyridine-3-carboxamide;N-[5-(1-cyclopropyl-2,6-dioxo-3-propyl-7H-purin-8-yl)-2-pyridinyl]-N-propylpyridine-3-carboxamide has a molecular weight of 3536.75 g/mol, XLogP of 23.34, 54 rotatable bonds, 7 hydrogen bond donors, and 57 hydrogen bond acceptors.
Where does this data come from?
All data for N-cyclopropyl-N-[5-(1-cyclopropyl-2,6-dioxo-3-propyl-7H-purin-8-yl)-2-pyridinyl]pyridine-3-carboxamide;N-[5-(1-cyclopropyl-2,6-dioxo-3-propyl-7H-purin-8-yl)-2-pyridinyl]-N-(cyclopropylmethyl)-6-(fluoromethyl)pyridine-3-carboxamide;N-[5-(1-cyclopropyl-2,6-dioxo-3-propyl-7H-purin-8-yl)-2-pyridinyl]-N-(cyclopropylmethyl)-6-(trifluoromethyl)pyridine-3-carboxamide;N-[5-(1-cyclopropyl-2,6-dioxo-3-propyl-7H-purin-8-yl)-2-pyridinyl]-N-ethylpyridine-3-carboxamide;N-[5-(1-cyclopropyl-2,6-dioxo-3-propyl-7H-purin-8-yl)-2-pyridinyl]-6-(fluoromethyl)-N-methylpyridine-3-carboxamide;N-[5-(1-cyclopropyl-2,6-dioxo-3-propyl-7H-purin-8-yl)-2-pyridinyl]-N-(oxolan-2-ylmethyl)-6-(trifluoromethyl)pyridine-3-carboxamide;N-[5-(1-cyclopropyl-2,6-dioxo-3-propyl-7H-purin-8-yl)-2-pyridinyl]-N-propylpyridine-3-carboxamide is sourced from PubChem (CID 159621420), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).