2-methyl-N-[6-(1-methylpyrazol-4-yl)isoquinolin-3-yl]-1,3-dihydroisoindole-5-carboxamide;6-(4-methylpiperazin-1-yl)-N-[6-(1-methylpyrazol-4-yl)isoquinolin-3-yl]pyridazine-4-carboxamide;6-(4-methylpiperazin-1-yl)-N-[6-(1-methylpyrazol-4-yl)isoquinolin-3-yl]pyrimidine-4-carboxamide;N-[6-(1-methylpyrazol-4-yl)isoquinolin-3-yl]-2,3-dihydro-1H-indene-5-carboxamide;bis(N-[6-(1-methylpyrazol-4-yl)isoquinolin-3-yl]-2-phenylacetamide);bis(N-[6-(1-methylpyrazol-4-yl)isoquinolin-3-yl]-3-phenylpropanamide);N-[6-(1-methylpyrazol-4-yl)isoquinolin-3-yl]-5,6,7,8-tetrahydronaphthalene-2-carboxamide

C202H187N45O9 — CID 159623072

IUPAC2-methyl-N-[6-(1-methylpyrazol-4-yl)isoquinolin-3-yl]-1,3-dihydroisoindole-5-carboxamide;6-(4-methylpiperazin-1-yl)-N-[6-(1-methylpyrazol-4-yl)isoquinolin-3-yl]pyridazine-4-carboxamide;6-(4-methylpiperazin-1-yl)-N-[6-(1-methylpyrazol-4-yl)isoquinolin-3-yl]pyrimidine-4-carboxamide;N-[6-(1-methylpyrazol-4-yl)isoquinolin-3-yl]-2,3-dihydro-1H-indene-5-carboxamide;bis(N-[6-(1-methylpyrazol-4-yl)isoquinolin-3-yl]-2-phenylacetamide);bis(N-[6-(1-methylpyrazol-4-yl)isoquinolin-3-yl]-3-phenylpropanamide);N-[6-(1-methylpyrazol-4-yl)isoquinolin-3-yl]-5,6,7,8-tetrahydronaphthalene-2-carboxamide
SMILESCN1CCN(c2cc(C(=O)Nc3cc4cc(-c5cnn(C)c5)ccc4cn3)cnn2)CC1.CN1CCN(c2cc(C(=O)Nc3cc4cc(-c5cnn(C)c5)ccc4cn3)ncn2)CC1.CN1Cc2ccc(C(=O)Nc3cc4cc(-c5cnn(C)c5)ccc4cn3)cc2C1.Cn1cc(-c2ccc3cnc(NC(=O)CCc4ccccc4)cc3c2)cn1.Cn1cc(-c2ccc3cnc(NC(=O)CCc4ccccc4)cc3c2)cn1.Cn1cc(-c2ccc3cnc(NC(=O)Cc4ccccc4)cc3c2)cn1.Cn1cc(-c2ccc3cnc(NC(=O)Cc4ccccc4)cc3c2)cn1.Cn1cc(-c2ccc3cnc(NC(=O)c4ccc5c(c4)CCC5)cc3c2)cn1.Cn1cc(-c2ccc3cnc(NC(=O)c4ccc5c(c4)CCCC5)cc3c2)cn1
InChIInChI=1S/C24H22N4O.2C23H24N8O.C23H21N5O.C23H20N4O.2C22H20N4O.2C21H18N4O/c1-28-15-22(14-26-28)18-7-9-20-13-25-23(12-21(20)11-18)27-24(29)19-8-6-16-4-2-3-5-17(16)10-19;1-29-5-7-31(8-6-29)22-11-20(25-15-26-22)23(32)28-21-10-18-9-16(3-4-17(18)12-24-21)19-13-27-30(2)14-19;1-29-5-7-31(8-6-29)22-11-19(13-25-28-22)23(32)27-21-10-18-9-16(3-4-17(18)12-24-21)20-14-26-30(2)15-20;1-27-12-18-6-4-16(8-20(18)13-27)23(29)26-22-9-19-7-15(3-5-17(19)10-24-22)21-11-25-28(2)14-21;1-27-14-21(13-25-27)17-6-8-19-12-24-22(11-20(19)10-17)26-23(28)18-7-5-15-3-2-4-16(15)9-18;2*1-26-15-20(14-24-26)17-8-9-18-13-23-21(12-19(18)11-17)25-22(27)10-7-16-5-3-2-4-6-16;2*1-25-14-19(13-23-25)16-7-8-17-12-22-20(11-18(17)10-16)24-21(26)9-15-5-3-2-4-6-15/h6-15H,2-5H2,1H3,(H,25,27,29);3-4,9-15H,5-8H2,1-2H3,(H,24,28,32);3-4,9-15H,5-8H2,1-2H3,(H,24,27,32);3-11,14H,12-13H2,1-2H3,(H,24,26,29);5-14H,2-4H2,1H3,(H,24,26,28);2*2-6,8-9,11-15H,7,10H2,1H3,(H,23,25,27);2*2-8,10-14H,9H2,1H3,(H,22,24,26)
InChIKeyMODGSLGLWHXYEP-UHFFFAOYSA-N
MW3389.02 g/mol
LogP33.88
Rot. Bonds35

About 2-methyl-N-[6-(1-methylpyrazol-4-yl)isoquinolin-3-yl]-1,3-dihydroisoindole-5-carboxamide;6-(4-methylpiperazin-1-yl)-N-[6-(1-methylpyrazol-4-yl)isoquinolin-3-yl]pyridazine-4-carboxamide;6-(4-methylpiperazin-1-yl)-N-[6-(1-methylpyrazol-4-yl)isoquinolin-3-yl]pyrimidine-4-carboxamide;N-[6-(1-methylpyrazol-4-yl)isoquinolin-3-yl]-2,3-dihydro-1H-indene-5-carboxamide;bis(N-[6-(1-methylpyrazol-4-yl)isoquinolin-3-yl]-2-phenylacetamide);bis(N-[6-(1-methylpyrazol-4-yl)isoquinolin-3-yl]-3-phenylpropanamide);N-[6-(1-methylpyrazol-4-yl)isoquinolin-3-yl]-5,6,7,8-tetrahydronaphthalene-2-carboxamide

2-methyl-N-[6-(1-methylpyrazol-4-yl)isoquinolin-3-yl]-1,3-dihydroisoindole-5-carboxamide;6-(4-methylpiperazin-1-yl)-N-[6-(1-methylpyrazol-4-yl)isoquinolin-3-yl]pyridazine-4-carboxamide;6-(4-methylpiperazin-1-yl)-N-[6-(1-methylpyrazol-4-yl)isoquinolin-3-yl]pyrimidine-4-carboxamide;N-[6-(1-methylpyrazol-4-yl)isoquinolin-3-yl]-2,3-dihydro-1H-indene-5-carboxamide;bis(N-[6-(1-methylpyrazol-4-yl)isoquinolin-3-yl]-2-phenylacetamide);bis(N-[6-(1-methylpyrazol-4-yl)isoquinolin-3-yl]-3-phenylpropanamide);N-[6-(1-methylpyrazol-4-yl)isoquinolin-3-yl]-5,6,7,8-tetrahydronaphthalene-2-carboxamide (PubChem CID 159623072) has the molecular formula C202H187N45O9 and a molecular weight of 3389.02 g/mol. Its IUPAC name is 2-methyl-N-[6-(1-methylpyrazol-4-yl)isoquinolin-3-yl]-1,3-dihydroisoindole-5-carboxamide;6-(4-methylpiperazin-1-yl)-N-[6-(1-methylpyrazol-4-yl)isoquinolin-3-yl]pyridazine-4-carboxamide;6-(4-methylpiperazin-1-yl)-N-[6-(1-methylpyrazol-4-yl)isoquinolin-3-yl]pyrimidine-4-carboxamide;N-[6-(1-methylpyrazol-4-yl)isoquinolin-3-yl]-2,3-dihydro-1H-indene-5-carboxamide;bis(N-[6-(1-methylpyrazol-4-yl)isoquinolin-3-yl]-2-phenylacetamide);bis(N-[6-(1-methylpyrazol-4-yl)isoquinolin-3-yl]-3-phenylpropanamide);N-[6-(1-methylpyrazol-4-yl)isoquinolin-3-yl]-5,6,7,8-tetrahydronaphthalene-2-carboxamide.

Molecular Properties

Compound Name2-methyl-N-[6-(1-methylpyrazol-4-yl)isoquinolin-3-yl]-1,3-dihydroisoindole-5-carboxamide;6-(4-methylpiperazin-1-yl)-N-[6-(1-methylpyrazol-4-yl)isoquinolin-3-yl]pyridazine-4-carboxamide;6-(4-methylpiperazin-1-yl)-N-[6-(1-methylpyrazol-4-yl)isoquinolin-3-yl]pyrimidine-4-carboxamide;N-[6-(1-methylpyrazol-4-yl)isoquinolin-3-yl]-2,3-dihydro-1H-indene-5-carboxamide;bis(N-[6-(1-methylpyrazol-4-yl)isoquinolin-3-yl]-2-phenylacetamide);bis(N-[6-(1-methylpyrazol-4-yl)isoquinolin-3-yl]-3-phenylpropanamide);N-[6-(1-methylpyrazol-4-yl)isoquinolin-3-yl]-5,6,7,8-tetrahydronaphthalene-2-carboxamide
PubChem CID159623072
Molecular FormulaC202H187N45O9
Molecular Weight3389.02 g/mol
Exact Mass3386.56
IUPAC Name2-methyl-N-[6-(1-methylpyrazol-4-yl)isoquinolin-3-yl]-1,3-dihydroisoindole-5-carboxamide;6-(4-methylpiperazin-1-yl)-N-[6-(1-methylpyrazol-4-yl)isoquinolin-3-yl]pyridazine-4-carboxamide;6-(4-methylpiperazin-1-yl)-N-[6-(1-methylpyrazol-4-yl)isoquinolin-3-yl]pyrimidine-4-carboxamide;N-[6-(1-methylpyrazol-4-yl)isoquinolin-3-yl]-2,3-dihydro-1H-indene-5-carboxamide;bis(N-[6-(1-methylpyrazol-4-yl)isoquinolin-3-yl]-2-phenylacetamide);bis(N-[6-(1-methylpyrazol-4-yl)isoquinolin-3-yl]-3-phenylpropanamide);N-[6-(1-methylpyrazol-4-yl)isoquinolin-3-yl]-5,6,7,8-tetrahydronaphthalene-2-carboxamide
SMILESCN1CCN(c2cc(C(=O)Nc3cc4cc(-c5cnn(C)c5)ccc4cn3)cnn2)CC1.CN1CCN(c2cc(C(=O)Nc3cc4cc(-c5cnn(C)c5)ccc4cn3)ncn2)CC1.CN1Cc2ccc(C(=O)Nc3cc4cc(-c5cnn(C)c5)ccc4cn3)cc2C1.Cn1cc(-c2ccc3cnc(NC(=O)CCc4ccccc4)cc3c2)cn1.Cn1cc(-c2ccc3cnc(NC(=O)CCc4ccccc4)cc3c2)cn1.Cn1cc(-c2ccc3cnc(NC(=O)Cc4ccccc4)cc3c2)cn1.Cn1cc(-c2ccc3cnc(NC(=O)Cc4ccccc4)cc3c2)cn1.Cn1cc(-c2ccc3cnc(NC(=O)c4ccc5c(c4)CCC5)cc3c2)cn1.Cn1cc(-c2ccc3cnc(NC(=O)c4ccc5c(c4)CCCC5)cc3c2)cn1
InChIInChI=1S/C24H22N4O.2C23H24N8O.C23H21N5O.C23H20N4O.2C22H20N4O.2C21H18N4O/c1-28-15-22(14-26-28)18-7-9-20-13-25-23(12-21(20)11-18)27-24(29)19-8-6-16-4-2-3-5-17(16)10-19;1-29-5-7-31(8-6-29)22-11-20(25-15-26-22)23(32)28-21-10-18-9-16(3-4-17(18)12-24-21)19-13-27-30(2)14-19;1-29-5-7-31(8-6-29)22-11-19(13-25-28-22)23(32)27-21-10-18-9-16(3-4-17(18)12-24-21)20-14-26-30(2)15-20;1-27-12-18-6-4-16(8-20(18)13-27)23(29)26-22-9-19-7-15(3-5-17(19)10-24-22)21-11-25-28(2)14-21;1-27-14-21(13-25-27)17-6-8-19-12-24-22(11-20(19)10-17)26-23(28)18-7-5-15-3-2-4-16(15)9-18;2*1-26-15-20(14-24-26)17-8-9-18-13-23-21(12-19(18)11-17)25-22(27)10-7-16-5-3-2-4-6-16;2*1-25-14-19(13-23-25)16-7-8-17-12-22-20(11-18(17)10-16)24-21(26)9-15-5-3-2-4-6-15/h6-15H,2-5H2,1H3,(H,25,27,29);3-4,9-15H,5-8H2,1-2H3,(H,24,28,32);3-4,9-15H,5-8H2,1-2H3,(H,24,27,32);3-11,14H,12-13H2,1-2H3,(H,24,26,29);5-14H,2-4H2,1H3,(H,24,26,28);2*2-6,8-9,11-15H,7,10H2,1H3,(H,23,25,27);2*2-8,10-14H,9H2,1H3,(H,22,24,26)
InChIKeyMODGSLGLWHXYEP-UHFFFAOYSA-N
XLogP33.88
TPSA606.05 Ų
H-Bond Donors9
H-Bond Acceptors45
Rotatable Bonds35
Heavy Atoms256
Complexity—

Lipinski Rule of Five

4 violations

RuleValue
MW ≤ 5003389.02
LogP ≤ 533.88
H-Bond Donors ≤ 59
H-Bond Acceptors ≤ 1045

Analyze 2-methyl-N-[6-(1-methylpyrazol-4-yl)isoquinolin-3-yl]-1,3-dihydroisoindole-5-carboxamide;6-(4-methylpiperazin-1-yl)-N-[6-(1-methylpyrazol-4-yl)isoquinolin-3-yl]pyridazine-4-carboxamide;6-(4-methylpiperazin-1-yl)-N-[6-(1-methylpyrazol-4-yl)isoquinolin-3-yl]pyrimidine-4-carboxamide;N-[6-(1-methylpyrazol-4-yl)isoquinolin-3-yl]-2,3-dihydro-1H-indene-5-carboxamide;bis(N-[6-(1-methylpyrazol-4-yl)isoquinolin-3-yl]-2-phenylacetamide);bis(N-[6-(1-methylpyrazol-4-yl)isoquinolin-3-yl]-3-phenylpropanamide);N-[6-(1-methylpyrazol-4-yl)isoquinolin-3-yl]-5,6,7,8-tetrahydronaphthalene-2-carboxamide with MolForge

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Related Compounds

7-N-[(1S)-5-acetyl-4-methyl-2,3-dihydro-1H-inden-1-yl]-5-N-[(2-fluoro-4-pyridinyl)methyl]pyrazolo[1,5-a]pyrimidine-5,7-dicarboxamide;7-N-[(1S)-5-acetyl-4-methyl-2,3-dihydro-1H-inden-1-yl]-5-N-[[4-fluoro-3-(trifluoromethyl)phenyl]methyl]pyrazolo[1,5-a]pyrimidine-5,7-dicarboxamide;7-N-[(1S)-5-acetyl-4-methyl-2,3-dihydro-1H-inden-1-yl]-5-N-[[3-(trifluoromethyl)phenyl]methyl]pyrazolo[1,5-a]pyrimidine-5,7-dicarboxamide;7-N-[(1S)-5-acetyl-4-methyl-2,3-dihydro-1H-inden-1-yl]-5-N-[[4-(trifluoromethyl)phenyl]methyl]pyrazolo[1,5-a]pyrimidine-5,7-dicarboxamide
CID 90758816
7-N-[(1S)-5-acetyl-4-methyl-2,3-dihydro-1H-inden-1-yl]-5-N-[(4-fluorophenyl)methyl]-[1,2,4]triazolo[1,5-a]pyrimidine-5,7-dicarboxamide;7-N-[(1S)-5-acetyl-4-methyl-2,3-dihydro-1H-inden-1-yl]-5-N-[(2-fluoro-4-pyridinyl)methyl]-[1,2,4]triazolo[1,5-a]pyrimidine-5,7-dicarboxamide;7-N-[(1S)-5-acetyl-4-methyl-2,3-dihydro-1H-inden-1-yl]-5-N-[(2-isocyano-4-pyridinyl)methyl]-[1,2,4]triazolo[1,5-a]pyrimidine-5,7-dicarboxamide;7-N-[(1S)-5-acetyl-4-methyl-2,3-dihydro-1H-inden-1-yl]-5-N-[[3-(trifluoromethyl)phenyl]methyl]-[1,2,4]triazolo[1,5-a]pyrimidine-5,7-dicarboxamide;7-N-[(1S)-5-acetyl-4-methyl-2,3-dihydro-1H-inden-1-yl]-5-N-[[4-(trifluoromethyl)phenyl]methyl]-[1,2,4]triazolo[1,5-a]pyrimidine-5,7-dicarboxamide
CID 90773520
7-N-[(1S)-5-acetyl-4-methyl-2,3-dihydro-1H-inden-1-yl]-3-fluoro-5-N-[(2-fluoro-4-pyridinyl)methyl]pyrazolo[1,5-a]pyrimidine-5,7-dicarboxamide;7-N-[(1S)-5-acetyl-4-methyl-2,3-dihydro-1H-inden-1-yl]-3-fluoro-5-N-[(2-isocyano-4-pyridinyl)methyl]pyrazolo[1,5-a]pyrimidine-5,7-dicarboxamide;7-N-[(1S)-5-acetyl-4-methyl-2,3-dihydro-1H-inden-1-yl]-3-fluoro-5-N-[[4-(trifluoromethyl)phenyl]methyl]pyrazolo[1,5-a]pyrimidine-5,7-dicarboxamide
CID 91095611
7-N-[(1S)-5-acetyl-4-methyl-2,3-dihydro-1H-inden-1-yl]-5-N-[(4-fluorophenyl)methyl]pyrazolo[1,5-a]pyrimidine-5,7-dicarboxamide;7-N-[(1S)-5-acetyl-4-methyl-2,3-dihydro-1H-inden-1-yl]-5-N-[(2-fluoro-4-pyridinyl)methyl]pyrazolo[1,5-a]pyrimidine-5,7-dicarboxamide;7-N-[(1S)-5-acetyl-4-methyl-2,3-dihydro-1H-inden-1-yl]-5-N-[(2-isocyano-4-pyridinyl)methyl]pyrazolo[1,5-a]pyrimidine-5,7-dicarboxamide;7-N-[(1S)-5-acetyl-4-methyl-2,3-dihydro-1H-inden-1-yl]-5-N-[[3-(trifluoromethyl)phenyl]methyl]pyrazolo[1,5-a]pyrimidine-5,7-dicarboxamide;7-N-[(1S)-5-acetyl-4-methyl-2,3-dihydro-1H-inden-1-yl]-5-N-[[4-(trifluoromethyl)phenyl]methyl]pyrazolo[1,5-a]pyrimidine-5,7-dicarboxamide
CID 91467421
7-N-[(1S)-5-acetyl-2,3-dihydro-1H-inden-1-yl]-5-N-[(2-fluoro-4-pyridinyl)methyl]pyrazolo[1,5-a]pyrimidine-5,7-dicarboxamide;7-N-[(1S)-5-acetyl-2,3-dihydro-1H-inden-1-yl]-5-N-[[4-fluoro-3-(trifluoromethyl)phenyl]methyl]pyrazolo[1,5-a]pyrimidine-5,7-dicarboxamide;7-N-[(1S)-5-acetyl-2,3-dihydro-1H-inden-1-yl]-5-N-[(2-isocyano-4-pyridinyl)methyl]pyrazolo[1,5-a]pyrimidine-5,7-dicarboxamide
CID 91495532
5-[1-[5-[3-carbamoyl-1-[2-[2-[[2-(3,4-dihydro-1H-isoquinolin-2-yl)-6-methyl-4-pyridinyl]carbamoyl]-4-fluoropyrrolidin-1-yl]-2-oxoethyl]indazol-5-yl]pyridazin-3-yl]pyridazin-1-ium-4-yl]-1-[2-[4-fluoro-2-[[2-(5-methyl-3-oxopyrazolidin-1-yl)-3-pyridinyl]carbamoyl]pyrrolidin-1-yl]-2-oxoethyl]indazole-3-carboxamide
CID 123927541
[4-[8-tert-butyl-6-(4-methylphenyl)imidazo[1,2-b]pyridazine-2-carbonyl]-3,3-dimethylpiperazin-1-yl]-pyridin-2-ylmethanone;[3,3-dimethyl-4-[8-propan-2-yl-6-[4-(trifluoromethyl)phenyl]imidazo[1,2-b]pyridazine-2-carbonyl]piperazin-1-yl]-(5-methyl-1H-pyrazol-3-yl)methanone;4-[6-(4-fluoro-3-methylphenyl)-8-propan-2-ylimidazo[1,2-b]pyridazine-2-carbonyl]-3,3-dimethyl-1-(2-methyl-1H-imidazol-5-yl)piperazin-2-one;4-[6-(4-fluoro-3-methylphenyl)-8-propan-2-ylimidazo[1,2-b]pyridazine-2-carbonyl]-3,3-dimethyl-1-(3H-pyrrol-5-yl)piperazin-2-one
CID 157222251
5-[3,3-dimethyl-1-(1-methylpyrazol-4-yl)-2-oxoindol-4-yl]-N-(4-methylphenyl)-2-(trifluoromethyl)benzamide;3-(3,3-dimethyl-2-oxo-1-pyrimidin-2-ylindol-4-yl)-2-fluoro-6-methyl-N-(4-methylphenyl)benzamide;5-(3,3-dimethyl-2-oxo-1-pyrimidin-2-ylindol-4-yl)-2-methyl-N-(4-methylphenyl)pyridine-3-carboxamide;5-[1-(5-fluoro-3-pyridinyl)-3,3-dimethyl-2-oxoindol-4-yl]-N-(4-methylphenyl)-2-(trifluoromethyl)pyridine-3-carboxamide
CID 157356270
bis((6-methyl-[1,2,4]triazolo[4,3-a]pyridin-3-yl)-[4-[2-(trifluoromethyl)phenyl]piperidin-1-yl]methanone);(7-methyl-[1,2,4]triazolo[4,3-a]pyridin-3-yl)-[4-[2-(trifluoromethyl)phenyl]piperidin-1-yl]methanone;N-methyl-3-[4-[2-(trifluoromethyl)phenyl]piperidine-1-carbonyl]-[1,2,4]triazolo[4,3-a]pyridine-6-carboxamide;1-[3-[4-[2-(trifluoromethyl)phenyl]piperidine-1-carbonyl]-[1,2,4]triazolo[4,3-a]pyridin-6-yl]ethanone;1-[3-[4-[2-(trifluoromethyl)phenyl]piperidine-1-carbonyl]-[1,2,4]triazolo[4,3-a]pyridin-7-yl]ethanone
CID 157362122
[8-tert-butyl-6-(4-fluoro-3-methylphenyl)imidazo[1,2-b]pyridazin-2-yl]-[2,2-dimethyl-4-(5-methyl-1H-1,2,4-triazole-3-carbonyl)piperazin-1-yl]methanone;[4-[8-tert-butyl-6-(3-methylphenyl)imidazo[1,2-b]pyridazine-2-carbonyl]-3,3-dimethylpiperazin-1-yl]-pyridin-2-ylmethanone;[8-tert-butyl-6-(3-methylphenyl)imidazo[1,2-b]pyridazin-2-yl]-[2,2-dimethyl-4-(pyrimidine-2-carbonyl)piperazin-1-yl]methanone;[2,2-dimethyl-4-(5-methyl-4H-imidazole-2-carbonyl)piperazin-1-yl]-[8-propan-2-yl-6-[4-(trifluoromethyl)phenyl]imidazo[1,2-b]pyridazin-2-yl]methanone
CID 157413742
(4R)-4-[3-(7H-cyclopenta[b]pyridin-3-yl)-6-[2-(1H-pyrrolo[2,3-b]pyridin-5-yl)ethynyl]-2-pyridinyl]-1-[3-(difluoromethyl)-4,4,7,7-tetrafluoro-5,6-dihydroindazol-1-yl]-5-(3,5-difluorophenyl)pentan-2-one;N-[(1S)-1-[5-(2-cyclopropylethynyl)-3-(2-methyl-3-oxo-1H-isoindol-5-yl)-2-pyridinyl]-2-(3,5-difluorophenyl)ethyl]-2-[3-(difluoromethyl)-4,4,7,7-tetrafluoro-5,6-dihydroindol-1-yl]acetamide;6-[2-[(2R)-5-[3-(difluoromethyl)-4,4,7,7-tetrafluoro-5,6-dihydroindol-1-yl]-1-(3,5-difluorophenyl)-4-oxopentan-2-yl]-6-(2-pyrimidin-5-ylethynyl)-3-pyridinyl]-2,3-dihydroinden-1-one
CID 157435113
4-[8-tert-butyl-6-(4,4-difluorocyclohexyl)imidazo[1,2-b]pyridazine-2-carbonyl]-3,3-dimethylpiperazin-2-one;4-[8-tert-butyl-6-(4,4-difluorocyclohexyl)imidazo[1,2-b]pyridazine-2-carbonyl]-3,3-dimethyl-1-(2H-pyrrol-4-yl)piperazin-2-one;[4-[8-tert-butyl-6-(3-fluoro-4-methylphenyl)imidazo[1,2-b]pyridazine-2-carbonyl]-3,3-dimethylpiperazin-1-yl]-(5-methyl-1H-pyrazol-3-yl)methanone;[8-tert-butyl-6-(3-fluoro-4-methylphenyl)imidazo[1,2-b]pyridazin-2-yl]-[2,2-dimethyl-4-(pyrimidine-2-carbonyl)piperazin-1-yl]methanone
CID 157445675

Frequently Asked Questions

What is the IUPAC name of 2-methyl-N-[6-(1-methylpyrazol-4-yl)isoquinolin-3-yl]-1,3-dihydroisoindole-5-carboxamide;6-(4-methylpiperazin-1-yl)-N-[6-(1-methylpyrazol-4-yl)isoquinolin-3-yl]pyridazine-4-carboxamide;6-(4-methylpiperazin-1-yl)-N-[6-(1-methylpyrazol-4-yl)isoquinolin-3-yl]pyrimidine-4-carboxamide;N-[6-(1-methylpyrazol-4-yl)isoquinolin-3-yl]-2,3-dihydro-1H-indene-5-carboxamide;bis(N-[6-(1-methylpyrazol-4-yl)isoquinolin-3-yl]-2-phenylacetamide);bis(N-[6-(1-methylpyrazol-4-yl)isoquinolin-3-yl]-3-phenylpropanamide);N-[6-(1-methylpyrazol-4-yl)isoquinolin-3-yl]-5,6,7,8-tetrahydronaphthalene-2-carboxamide?
The IUPAC name of 2-methyl-N-[6-(1-methylpyrazol-4-yl)isoquinolin-3-yl]-1,3-dihydroisoindole-5-carboxamide;6-(4-methylpiperazin-1-yl)-N-[6-(1-methylpyrazol-4-yl)isoquinolin-3-yl]pyridazine-4-carboxamide;6-(4-methylpiperazin-1-yl)-N-[6-(1-methylpyrazol-4-yl)isoquinolin-3-yl]pyrimidine-4-carboxamide;N-[6-(1-methylpyrazol-4-yl)isoquinolin-3-yl]-2,3-dihydro-1H-indene-5-carboxamide;bis(N-[6-(1-methylpyrazol-4-yl)isoquinolin-3-yl]-2-phenylacetamide);bis(N-[6-(1-methylpyrazol-4-yl)isoquinolin-3-yl]-3-phenylpropanamide);N-[6-(1-methylpyrazol-4-yl)isoquinolin-3-yl]-5,6,7,8-tetrahydronaphthalene-2-carboxamide (CID 159623072) is 2-methyl-N-[6-(1-methylpyrazol-4-yl)isoquinolin-3-yl]-1,3-dihydroisoindole-5-carboxamide;6-(4-methylpiperazin-1-yl)-N-[6-(1-methylpyrazol-4-yl)isoquinolin-3-yl]pyridazine-4-carboxamide;6-(4-methylpiperazin-1-yl)-N-[6-(1-methylpyrazol-4-yl)isoquinolin-3-yl]pyrimidine-4-carboxamide;N-[6-(1-methylpyrazol-4-yl)isoquinolin-3-yl]-2,3-dihydro-1H-indene-5-carboxamide;bis(N-[6-(1-methylpyrazol-4-yl)isoquinolin-3-yl]-2-phenylacetamide);bis(N-[6-(1-methylpyrazol-4-yl)isoquinolin-3-yl]-3-phenylpropanamide);N-[6-(1-methylpyrazol-4-yl)isoquinolin-3-yl]-5,6,7,8-tetrahydronaphthalene-2-carboxamide.
What is the SMILES notation for 2-methyl-N-[6-(1-methylpyrazol-4-yl)isoquinolin-3-yl]-1,3-dihydroisoindole-5-carboxamide;6-(4-methylpiperazin-1-yl)-N-[6-(1-methylpyrazol-4-yl)isoquinolin-3-yl]pyridazine-4-carboxamide;6-(4-methylpiperazin-1-yl)-N-[6-(1-methylpyrazol-4-yl)isoquinolin-3-yl]pyrimidine-4-carboxamide;N-[6-(1-methylpyrazol-4-yl)isoquinolin-3-yl]-2,3-dihydro-1H-indene-5-carboxamide;bis(N-[6-(1-methylpyrazol-4-yl)isoquinolin-3-yl]-2-phenylacetamide);bis(N-[6-(1-methylpyrazol-4-yl)isoquinolin-3-yl]-3-phenylpropanamide);N-[6-(1-methylpyrazol-4-yl)isoquinolin-3-yl]-5,6,7,8-tetrahydronaphthalene-2-carboxamide?
The canonical SMILES for 2-methyl-N-[6-(1-methylpyrazol-4-yl)isoquinolin-3-yl]-1,3-dihydroisoindole-5-carboxamide;6-(4-methylpiperazin-1-yl)-N-[6-(1-methylpyrazol-4-yl)isoquinolin-3-yl]pyridazine-4-carboxamide;6-(4-methylpiperazin-1-yl)-N-[6-(1-methylpyrazol-4-yl)isoquinolin-3-yl]pyrimidine-4-carboxamide;N-[6-(1-methylpyrazol-4-yl)isoquinolin-3-yl]-2,3-dihydro-1H-indene-5-carboxamide;bis(N-[6-(1-methylpyrazol-4-yl)isoquinolin-3-yl]-2-phenylacetamide);bis(N-[6-(1-methylpyrazol-4-yl)isoquinolin-3-yl]-3-phenylpropanamide);N-[6-(1-methylpyrazol-4-yl)isoquinolin-3-yl]-5,6,7,8-tetrahydronaphthalene-2-carboxamide is CN1CCN(c2cc(C(=O)Nc3cc4cc(-c5cnn(C)c5)ccc4cn3)cnn2)CC1.CN1CCN(c2cc(C(=O)Nc3cc4cc(-c5cnn(C)c5)ccc4cn3)ncn2)CC1.CN1Cc2ccc(C(=O)Nc3cc4cc(-c5cnn(C)c5)ccc4cn3)cc2C1.Cn1cc(-c2ccc3cnc(NC(=O)CCc4ccccc4)cc3c2)cn1.Cn1cc(-c2ccc3cnc(NC(=O)CCc4ccccc4)cc3c2)cn1.Cn1cc(-c2ccc3cnc(NC(=O)Cc4ccccc4)cc3c2)cn1.Cn1cc(-c2ccc3cnc(NC(=O)Cc4ccccc4)cc3c2)cn1.Cn1cc(-c2ccc3cnc(NC(=O)c4ccc5c(c4)CCC5)cc3c2)cn1.Cn1cc(-c2ccc3cnc(NC(=O)c4ccc5c(c4)CCCC5)cc3c2)cn1.
What is the InChIKey of 2-methyl-N-[6-(1-methylpyrazol-4-yl)isoquinolin-3-yl]-1,3-dihydroisoindole-5-carboxamide;6-(4-methylpiperazin-1-yl)-N-[6-(1-methylpyrazol-4-yl)isoquinolin-3-yl]pyridazine-4-carboxamide;6-(4-methylpiperazin-1-yl)-N-[6-(1-methylpyrazol-4-yl)isoquinolin-3-yl]pyrimidine-4-carboxamide;N-[6-(1-methylpyrazol-4-yl)isoquinolin-3-yl]-2,3-dihydro-1H-indene-5-carboxamide;bis(N-[6-(1-methylpyrazol-4-yl)isoquinolin-3-yl]-2-phenylacetamide);bis(N-[6-(1-methylpyrazol-4-yl)isoquinolin-3-yl]-3-phenylpropanamide);N-[6-(1-methylpyrazol-4-yl)isoquinolin-3-yl]-5,6,7,8-tetrahydronaphthalene-2-carboxamide?
The InChIKey is MODGSLGLWHXYEP-UHFFFAOYSA-N. The full InChI is InChI=1S/C24H22N4O.2C23H24N8O.C23H21N5O.C23H20N4O.2C22H20N4O.2C21H18N4O/c1-28-15-22(14-26-28)18-7-9-20-13-25-23(12-21(20)11-18)27-24(29)19-8-6-16-4-2-3-5-17(16)10-19;1-29-5-7-31(8-6-29)22-11-20(25-15-26-22)23(32)28-21-10-18-9-16(3-4-17(18)12-24-21)19-13-27-30(2)14-19;1-29-5-7-31(8-6-29)22-11-19(13-25-28-22)23(32)27-21-10-18-9-16(3-4-17(18)12-24-21)20-14-26-30(2)15-20;1-27-12-18-6-4-16(8-20(18)13-27)23(29)26-22-9-19-7-15(3-5-17(19)10-24-22)21-11-25-28(2)14-21;1-27-14-21(13-25-27)17-6-8-19-12-24-22(11-20(19)10-17)26-23(28)18-7-5-15-3-2-4-16(15)9-18;2*1-26-15-20(14-24-26)17-8-9-18-13-23-21(12-19(18)11-17)25-22(27)10-7-16-5-3-2-4-6-16;2*1-25-14-19(13-23-25)16-7-8-17-12-22-20(11-18(17)10-16)24-21(26)9-15-5-3-2-4-6-15/h6-15H,2-5H2,1H3,(H,25,27,29);3-4,9-15H,5-8H2,1-2H3,(H,24,28,32);3-4,9-15H,5-8H2,1-2H3,(H,24,27,32);3-11,14H,12-13H2,1-2H3,(H,24,26,29);5-14H,2-4H2,1H3,(H,24,26,28);2*2-6,8-9,11-15H,7,10H2,1H3,(H,23,25,27);2*2-8,10-14H,9H2,1H3,(H,22,24,26).
What are the key properties of 2-methyl-N-[6-(1-methylpyrazol-4-yl)isoquinolin-3-yl]-1,3-dihydroisoindole-5-carboxamide;6-(4-methylpiperazin-1-yl)-N-[6-(1-methylpyrazol-4-yl)isoquinolin-3-yl]pyridazine-4-carboxamide;6-(4-methylpiperazin-1-yl)-N-[6-(1-methylpyrazol-4-yl)isoquinolin-3-yl]pyrimidine-4-carboxamide;N-[6-(1-methylpyrazol-4-yl)isoquinolin-3-yl]-2,3-dihydro-1H-indene-5-carboxamide;bis(N-[6-(1-methylpyrazol-4-yl)isoquinolin-3-yl]-2-phenylacetamide);bis(N-[6-(1-methylpyrazol-4-yl)isoquinolin-3-yl]-3-phenylpropanamide);N-[6-(1-methylpyrazol-4-yl)isoquinolin-3-yl]-5,6,7,8-tetrahydronaphthalene-2-carboxamide?
2-methyl-N-[6-(1-methylpyrazol-4-yl)isoquinolin-3-yl]-1,3-dihydroisoindole-5-carboxamide;6-(4-methylpiperazin-1-yl)-N-[6-(1-methylpyrazol-4-yl)isoquinolin-3-yl]pyridazine-4-carboxamide;6-(4-methylpiperazin-1-yl)-N-[6-(1-methylpyrazol-4-yl)isoquinolin-3-yl]pyrimidine-4-carboxamide;N-[6-(1-methylpyrazol-4-yl)isoquinolin-3-yl]-2,3-dihydro-1H-indene-5-carboxamide;bis(N-[6-(1-methylpyrazol-4-yl)isoquinolin-3-yl]-2-phenylacetamide);bis(N-[6-(1-methylpyrazol-4-yl)isoquinolin-3-yl]-3-phenylpropanamide);N-[6-(1-methylpyrazol-4-yl)isoquinolin-3-yl]-5,6,7,8-tetrahydronaphthalene-2-carboxamide has a molecular weight of 3389.02 g/mol, XLogP of 33.88, 35 rotatable bonds, 9 hydrogen bond donors, and 45 hydrogen bond acceptors.
Where does this data come from?
All data for 2-methyl-N-[6-(1-methylpyrazol-4-yl)isoquinolin-3-yl]-1,3-dihydroisoindole-5-carboxamide;6-(4-methylpiperazin-1-yl)-N-[6-(1-methylpyrazol-4-yl)isoquinolin-3-yl]pyridazine-4-carboxamide;6-(4-methylpiperazin-1-yl)-N-[6-(1-methylpyrazol-4-yl)isoquinolin-3-yl]pyrimidine-4-carboxamide;N-[6-(1-methylpyrazol-4-yl)isoquinolin-3-yl]-2,3-dihydro-1H-indene-5-carboxamide;bis(N-[6-(1-methylpyrazol-4-yl)isoquinolin-3-yl]-2-phenylacetamide);bis(N-[6-(1-methylpyrazol-4-yl)isoquinolin-3-yl]-3-phenylpropanamide);N-[6-(1-methylpyrazol-4-yl)isoquinolin-3-yl]-5,6,7,8-tetrahydronaphthalene-2-carboxamide is sourced from PubChem (CID 159623072), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).