(2R)-3-[3-(2-ethoxy-4-pyridinyl)-3-[(3-methylphenyl)methyl]-2H-indol-1-yl]-1,1,1-trifluoropropan-2-ol;(2R)-1,1,1-trifluoro-3-[3-[(3-methylphenyl)methyl]-3-[3-(3-methylphenyl)phenyl]-2H-indol-1-yl]propan-2-ol;(2R)-1,1,1-trifluoro-3-[3-[(3-methylphenyl)methyl]-3-(2-methyl-4-pyridinyl)-2H-indol-1-yl]propan-2-ol;(2R)-1,1,1-trifluoro-3-[3-[(3-methylphenyl)methyl]-3-(2-morpholin-4-yl-4-pyridinyl)-2H-indol-1-yl]propan-2-ol;(2R)-1,1,1-trifluoro-3-[3-[(3-methylphenyl)methyl]-3-(2-propan-2-yloxy-4-pyridinyl)-2H-indol-1-yl]propan-2-ol

C138H141F15N10O8 — CID 159647310

About (2R)-3-[3-(2-ethoxy-4-pyridinyl)-3-[(3-methylphenyl)methyl]-2H-indol-1-yl]-1,1,1-trifluoropropan-2-ol;(2R)-1,1,1-trifluoro-3-[3-[(3-methylphenyl)methyl]-3-[3-(3-methylphenyl)phenyl]-2H-indol-1-yl]propan-2-ol;(2R)-1,1,1-trifluoro-3-[3-[(3-methylphenyl)methyl]-3-(2-methyl-4-pyridinyl)-2H-indol-1-yl]propan-2-ol;(2R)-1,1,1-trifluoro-3-[3-[(3-methylphenyl)methyl]-3-(2-morpholin-4-yl-4-pyridinyl)-2H-indol-1-yl]propan-2-ol;(2R)-1,1,1-trifluoro-3-[3-[(3-methylphenyl)methyl]-3-(2-propan-2-yloxy-4-pyridinyl)-2H-indol-1-yl]propan-2-ol

(2R)-3-[3-(2-ethoxy-4-pyridinyl)-3-[(3-methylphenyl)methyl]-2H-indol-1-yl]-1,1,1-trifluoropropan-2-ol;(2R)-1,1,1-trifluoro-3-[3-[(3-methylphenyl)methyl]-3-[3-(3-methylphenyl)phenyl]-2H-indol-1-yl]propan-2-ol;(2R)-1,1,1-trifluoro-3-[3-[(3-methylphenyl)methyl]-3-(2-methyl-4-pyridinyl)-2H-indol-1-yl]propan-2-ol;(2R)-1,1,1-trifluoro-3-[3-[(3-methylphenyl)methyl]-3-(2-morpholin-4-yl-4-pyridinyl)-2H-indol-1-yl]propan-2-ol;(2R)-1,1,1-trifluoro-3-[3-[(3-methylphenyl)methyl]-3-(2-propan-2-yloxy-4-pyridinyl)-2H-indol-1-yl]propan-2-ol (PubChem CID 159647310) has the molecular formula C138H141F15N10O8 and a molecular weight of 2352.68 g/mol. Its IUPAC name is (2R)-3-[3-(2-ethoxy-4-pyridinyl)-3-[(3-methylphenyl)methyl]-2H-indol-1-yl]-1,1,1-trifluoropropan-2-ol;(2R)-1,1,1-trifluoro-3-[3-[(3-methylphenyl)methyl]-3-[3-(3-methylphenyl)phenyl]-2H-indol-1-yl]propan-2-ol;(2R)-1,1,1-trifluoro-3-[3-[(3-methylphenyl)methyl]-3-(2-methyl-4-pyridinyl)-2H-indol-1-yl]propan-2-ol;(2R)-1,1,1-trifluoro-3-[3-[(3-methylphenyl)methyl]-3-(2-morpholin-4-yl-4-pyridinyl)-2H-indol-1-yl]propan-2-ol;(2R)-1,1,1-trifluoro-3-[3-[(3-methylphenyl)methyl]-3-(2-propan-2-yloxy-4-pyridinyl)-2H-indol-1-yl]propan-2-ol.

Molecular Properties

• Compound Name: (2R)-3-[3-(2-ethoxy-4-pyridinyl)-3-[(3-methylphenyl)methyl]-2H-indol-1-yl]-1,1,1-trifluoropropan-2-ol;(2R)-1,1,1-trifluoro-3-[3-[(3-methylphenyl)methyl]-3-[3-(3-methylphenyl)phenyl]-2H-indol-1-yl]propan-2-ol;(2R)-1,1,1-trifluoro-3-[3-[(3-methylphenyl)methyl]-3-(2-methyl-4-pyridinyl)-2H-indol-1-yl]propan-2-ol;(2R)-1,1,1-trifluoro-3-[3-[(3-methylphenyl)methyl]-3-(2-morpholin-4-yl-4-pyridinyl)-2H-indol-1-yl]propan-2-ol;(2R)-1,1,1-trifluoro-3-[3-[(3-methylphenyl)methyl]-3-(2-propan-2-yloxy-4-pyridinyl)-2H-indol-1-yl]propan-2-ol
• PubChem CID: 159647310
• Molecular Formula: C138H141F15N10O8
• Molecular Weight: 2352.68 g/mol
• Exact Mass: 2351.07
• IUPAC Name: (2R)-3-[3-(2-ethoxy-4-pyridinyl)-3-[(3-methylphenyl)methyl]-2H-indol-1-yl]-1,1,1-trifluoropropan-2-ol;(2R)-1,1,1-trifluoro-3-[3-[(3-methylphenyl)methyl]-3-[3-(3-methylphenyl)phenyl]-2H-indol-1-yl]propan-2-ol;(2R)-1,1,1-trifluoro-3-[3-[(3-methylphenyl)methyl]-3-(2-methyl-4-pyridinyl)-2H-indol-1-yl]propan-2-ol;(2R)-1,1,1-trifluoro-3-[3-[(3-methylphenyl)methyl]-3-(2-morpholin-4-yl-4-pyridinyl)-2H-indol-1-yl]propan-2-ol;(2R)-1,1,1-trifluoro-3-[3-[(3-methylphenyl)methyl]-3-(2-propan-2-yloxy-4-pyridinyl)-2H-indol-1-yl]propan-2-ol
• SMILES: CCOc1cc(C2(Cc3cccc(C)c3)CN(C[C@@H](O)C(F)(F)F)c3ccccc32)ccn1.Cc1cccc(CC2(c3cccc(-c4cccc(C)c4)c3)CN(C[C@@H](O)C(F)(F)F)c3ccccc32)c1.Cc1cccc(CC2(c3ccnc(C)c3)CN(C[C@@H](O)C(F)(F)F)c3ccccc32)c1.Cc1cccc(CC2(c3ccnc(N4CCOCC4)c3)CN(C[C@@H](O)C(F)(F)F)c3ccccc32)c1.Cc1cccc(CC2(c3ccnc(OC(C)C)c3)CN(C[C@@H](O)C(F)(F)F)c3ccccc32)c1
• InChI: InChI=1S/C32H30F3NO.C28H30F3N3O2.C27H29F3N2O2.C26H27F3N2O2.C25H25F3N2O/c1-22-8-5-10-24(16-22)19-31(27-13-7-12-26(18-27)25-11-6-9-23(2)17-25)21-36(20-30(37)32(33,34)35)29-15-4-3-14-28(29)31;1-20-5-4-6-21(15-20)17-27(22-9-10-32-26(16-22)33-11-13-36-14-12-33)19-34(18-25(35)28(29,30)31)24-8-3-2-7-23(24)27;1-18(2)34-25-14-21(11-12-31-25)26(15-20-8-6-7-19(3)13-20)17-32(16-24(33)27(28,29)30)23-10-5-4-9-22(23)26;1-3-33-24-14-20(11-12-30-24)25(15-19-8-6-7-18(2)13-19)17-31(16-23(32)26(27,28)29)22-10-5-4-9-21(22)25;1-17-6-5-7-19(12-17)14-24(20-10-11-29-18(2)13-20)16-30(15-23(31)25(26,27)28)22-9-4-3-8-21(22)24/h3-18,30,37H,19-21H2,1-2H3;2-10,15-16,25,35H,11-14,17-19H2,1H3;4-14,18,24,33H,15-17H2,1-3H3;4-14,23,32H,3,15-17H2,1-2H3;3-13,23,31H,14-16H2,1-2H3/t30-,31?;25-,27?;24-,26?;23-,25?;23-,24?/m11111/s1
• InChIKey: MRCSEVGZMLRTKJ-XVRKLJILSA-N
• XLogP: 27.22
• TPSA: 199.84 Ų
• H-Bond Donors: 5
• H-Bond Acceptors: 18
• Rotatable Bonds: 31
• Heavy Atoms: 171
• Complexity: —

Lipinski Rule of Five

3 violations

Rule	Value
MW ≤ 500	2352.68
LogP ≤ 5	27.22
H-Bond Donors ≤ 5	5
H-Bond Acceptors ≤ 10	18

Frequently Asked Questions

What is the IUPAC name of (2R)-3-[3-(2-ethoxy-4-pyridinyl)-3-[(3-methylphenyl)methyl]-2H-indol-1-yl]-1,1,1-trifluoropropan-2-ol;(2R)-1,1,1-trifluoro-3-[3-[(3-methylphenyl)methyl]-3-[3-(3-methylphenyl)phenyl]-2H-indol-1-yl]propan-2-ol;(2R)-1,1,1-trifluoro-3-[3-[(3-methylphenyl)methyl]-3-(2-methyl-4-pyridinyl)-2H-indol-1-yl]propan-2-ol;(2R)-1,1,1-trifluoro-3-[3-[(3-methylphenyl)methyl]-3-(2-morpholin-4-yl-4-pyridinyl)-2H-indol-1-yl]propan-2-ol;(2R)-1,1,1-trifluoro-3-[3-[(3-methylphenyl)methyl]-3-(2-propan-2-yloxy-4-pyridinyl)-2H-indol-1-yl]propan-2-ol?

The IUPAC name of (2R)-3-[3-(2-ethoxy-4-pyridinyl)-3-[(3-methylphenyl)methyl]-2H-indol-1-yl]-1,1,1-trifluoropropan-2-ol;(2R)-1,1,1-trifluoro-3-[3-[(3-methylphenyl)methyl]-3-[3-(3-methylphenyl)phenyl]-2H-indol-1-yl]propan-2-ol;(2R)-1,1,1-trifluoro-3-[3-[(3-methylphenyl)methyl]-3-(2-methyl-4-pyridinyl)-2H-indol-1-yl]propan-2-ol;(2R)-1,1,1-trifluoro-3-[3-[(3-methylphenyl)methyl]-3-(2-morpholin-4-yl-4-pyridinyl)-2H-indol-1-yl]propan-2-ol;(2R)-1,1,1-trifluoro-3-[3-[(3-methylphenyl)methyl]-3-(2-propan-2-yloxy-4-pyridinyl)-2H-indol-1-yl]propan-2-ol (CID 159647310) is (2R)-3-[3-(2-ethoxy-4-pyridinyl)-3-[(3-methylphenyl)methyl]-2H-indol-1-yl]-1,1,1-trifluoropropan-2-ol;(2R)-1,1,1-trifluoro-3-[3-[(3-methylphenyl)methyl]-3-[3-(3-methylphenyl)phenyl]-2H-indol-1-yl]propan-2-ol;(2R)-1,1,1-trifluoro-3-[3-[(3-methylphenyl)methyl]-3-(2-methyl-4-pyridinyl)-2H-indol-1-yl]propan-2-ol;(2R)-1,1,1-trifluoro-3-[3-[(3-methylphenyl)methyl]-3-(2-morpholin-4-yl-4-pyridinyl)-2H-indol-1-yl]propan-2-ol;(2R)-1,1,1-trifluoro-3-[3-[(3-methylphenyl)methyl]-3-(2-propan-2-yloxy-4-pyridinyl)-2H-indol-1-yl]propan-2-ol.

What is the SMILES notation for (2R)-3-[3-(2-ethoxy-4-pyridinyl)-3-[(3-methylphenyl)methyl]-2H-indol-1-yl]-1,1,1-trifluoropropan-2-ol;(2R)-1,1,1-trifluoro-3-[3-[(3-methylphenyl)methyl]-3-[3-(3-methylphenyl)phenyl]-2H-indol-1-yl]propan-2-ol;(2R)-1,1,1-trifluoro-3-[3-[(3-methylphenyl)methyl]-3-(2-methyl-4-pyridinyl)-2H-indol-1-yl]propan-2-ol;(2R)-1,1,1-trifluoro-3-[3-[(3-methylphenyl)methyl]-3-(2-morpholin-4-yl-4-pyridinyl)-2H-indol-1-yl]propan-2-ol;(2R)-1,1,1-trifluoro-3-[3-[(3-methylphenyl)methyl]-3-(2-propan-2-yloxy-4-pyridinyl)-2H-indol-1-yl]propan-2-ol?

The canonical SMILES for (2R)-3-[3-(2-ethoxy-4-pyridinyl)-3-[(3-methylphenyl)methyl]-2H-indol-1-yl]-1,1,1-trifluoropropan-2-ol;(2R)-1,1,1-trifluoro-3-[3-[(3-methylphenyl)methyl]-3-[3-(3-methylphenyl)phenyl]-2H-indol-1-yl]propan-2-ol;(2R)-1,1,1-trifluoro-3-[3-[(3-methylphenyl)methyl]-3-(2-methyl-4-pyridinyl)-2H-indol-1-yl]propan-2-ol;(2R)-1,1,1-trifluoro-3-[3-[(3-methylphenyl)methyl]-3-(2-morpholin-4-yl-4-pyridinyl)-2H-indol-1-yl]propan-2-ol;(2R)-1,1,1-trifluoro-3-[3-[(3-methylphenyl)methyl]-3-(2-propan-2-yloxy-4-pyridinyl)-2H-indol-1-yl]propan-2-ol is CCOc1cc(C2(Cc3cccc(C)c3)CN(C[C@@H](O)C(F)(F)F)c3ccccc32)ccn1.Cc1cccc(CC2(c3cccc(-c4cccc(C)c4)c3)CN(C[C@@H](O)C(F)(F)F)c3ccccc32)c1.Cc1cccc(CC2(c3ccnc(C)c3)CN(C[C@@H](O)C(F)(F)F)c3ccccc32)c1.Cc1cccc(CC2(c3ccnc(N4CCOCC4)c3)CN(C[C@@H](O)C(F)(F)F)c3ccccc32)c1.Cc1cccc(CC2(c3ccnc(OC(C)C)c3)CN(C[C@@H](O)C(F)(F)F)c3ccccc32)c1.

What is the InChIKey of (2R)-3-[3-(2-ethoxy-4-pyridinyl)-3-[(3-methylphenyl)methyl]-2H-indol-1-yl]-1,1,1-trifluoropropan-2-ol;(2R)-1,1,1-trifluoro-3-[3-[(3-methylphenyl)methyl]-3-[3-(3-methylphenyl)phenyl]-2H-indol-1-yl]propan-2-ol;(2R)-1,1,1-trifluoro-3-[3-[(3-methylphenyl)methyl]-3-(2-methyl-4-pyridinyl)-2H-indol-1-yl]propan-2-ol;(2R)-1,1,1-trifluoro-3-[3-[(3-methylphenyl)methyl]-3-(2-morpholin-4-yl-4-pyridinyl)-2H-indol-1-yl]propan-2-ol;(2R)-1,1,1-trifluoro-3-[3-[(3-methylphenyl)methyl]-3-(2-propan-2-yloxy-4-pyridinyl)-2H-indol-1-yl]propan-2-ol?

The InChIKey is MRCSEVGZMLRTKJ-XVRKLJILSA-N. The full InChI is InChI=1S/C32H30F3NO.C28H30F3N3O2.C27H29F3N2O2.C26H27F3N2O2.C25H25F3N2O/c1-22-8-5-10-24(16-22)19-31(27-13-7-12-26(18-27)25-11-6-9-23(2)17-25)21-36(20-30(37)32(33,34)35)29-15-4-3-14-28(29)31;1-20-5-4-6-21(15-20)17-27(22-9-10-32-26(16-22)33-11-13-36-14-12-33)19-34(18-25(35)28(29,30)31)24-8-3-2-7-23(24)27;1-18(2)34-25-14-21(11-12-31-25)26(15-20-8-6-7-19(3)13-20)17-32(16-24(33)27(28,29)30)23-10-5-4-9-22(23)26;1-3-33-24-14-20(11-12-30-24)25(15-19-8-6-7-18(2)13-19)17-31(16-23(32)26(27,28)29)22-10-5-4-9-21(22)25;1-17-6-5-7-19(12-17)14-24(20-10-11-29-18(2)13-20)16-30(15-23(31)25(26,27)28)22-9-4-3-8-21(22)24/h3-18,30,37H,19-21H2,1-2H3;2-10,15-16,25,35H,11-14,17-19H2,1H3;4-14,18,24,33H,15-17H2,1-3H3;4-14,23,32H,3,15-17H2,1-2H3;3-13,23,31H,14-16H2,1-2H3/t30-,31?;25-,27?;24-,26?;23-,25?;23-,24?/m11111/s1.

What are the key properties of (2R)-3-[3-(2-ethoxy-4-pyridinyl)-3-[(3-methylphenyl)methyl]-2H-indol-1-yl]-1,1,1-trifluoropropan-2-ol;(2R)-1,1,1-trifluoro-3-[3-[(3-methylphenyl)methyl]-3-[3-(3-methylphenyl)phenyl]-2H-indol-1-yl]propan-2-ol;(2R)-1,1,1-trifluoro-3-[3-[(3-methylphenyl)methyl]-3-(2-methyl-4-pyridinyl)-2H-indol-1-yl]propan-2-ol;(2R)-1,1,1-trifluoro-3-[3-[(3-methylphenyl)methyl]-3-(2-morpholin-4-yl-4-pyridinyl)-2H-indol-1-yl]propan-2-ol;(2R)-1,1,1-trifluoro-3-[3-[(3-methylphenyl)methyl]-3-(2-propan-2-yloxy-4-pyridinyl)-2H-indol-1-yl]propan-2-ol?

(2R)-3-[3-(2-ethoxy-4-pyridinyl)-3-[(3-methylphenyl)methyl]-2H-indol-1-yl]-1,1,1-trifluoropropan-2-ol;(2R)-1,1,1-trifluoro-3-[3-[(3-methylphenyl)methyl]-3-[3-(3-methylphenyl)phenyl]-2H-indol-1-yl]propan-2-ol;(2R)-1,1,1-trifluoro-3-[3-[(3-methylphenyl)methyl]-3-(2-methyl-4-pyridinyl)-2H-indol-1-yl]propan-2-ol;(2R)-1,1,1-trifluoro-3-[3-[(3-methylphenyl)methyl]-3-(2-morpholin-4-yl-4-pyridinyl)-2H-indol-1-yl]propan-2-ol;(2R)-1,1,1-trifluoro-3-[3-[(3-methylphenyl)methyl]-3-(2-propan-2-yloxy-4-pyridinyl)-2H-indol-1-yl]propan-2-ol has a molecular weight of 2352.68 g/mol, XLogP of 27.22, 31 rotatable bonds, 5 hydrogen bond donors, and 18 hydrogen bond acceptors.

Where does this data come from?

All data for (2R)-3-[3-(2-ethoxy-4-pyridinyl)-3-[(3-methylphenyl)methyl]-2H-indol-1-yl]-1,1,1-trifluoropropan-2-ol;(2R)-1,1,1-trifluoro-3-[3-[(3-methylphenyl)methyl]-3-[3-(3-methylphenyl)phenyl]-2H-indol-1-yl]propan-2-ol;(2R)-1,1,1-trifluoro-3-[3-[(3-methylphenyl)methyl]-3-(2-methyl-4-pyridinyl)-2H-indol-1-yl]propan-2-ol;(2R)-1,1,1-trifluoro-3-[3-[(3-methylphenyl)methyl]-3-(2-morpholin-4-yl-4-pyridinyl)-2H-indol-1-yl]propan-2-ol;(2R)-1,1,1-trifluoro-3-[3-[(3-methylphenyl)methyl]-3-(2-propan-2-yloxy-4-pyridinyl)-2H-indol-1-yl]propan-2-ol is sourced from PubChem (CID 159647310), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).