bis(2-[1-[6-[6-amino-5-(difluoromethoxy)-3-pyridinyl]-2-[3-fluoro-3-(methoxymethyl)pyrrolidin-1-yl]pyrimidin-4-yl]-3-fluoropyrrolidin-3-yl]ethanol);3-(difluoromethoxy)-5-[2-(4,4-difluoropiperidin-1-yl)-6-[(1S,4S)-2-oxa-5-azabicyclo[2.2.1]heptan-5-yl]pyrimidin-4-yl]pyridin-2-amine;3-(difluoromethoxy)-5-[2-(3-fluoropiperidin-1-yl)-6-[(1S,4S)-2-oxa-5-azabicyclo[2.2.1]heptan-5-yl]pyrimidin-4-yl]pyridin-2-amine;3-fluoro-5-[2-(3-fluoro-3-methylpyrrolidin-1-yl)-6-[(1S,4S)-2-oxa-5-azabicyclo[2.2.1]heptan-5-yl]pyrimidin-4-yl]pyridin-2-amine

C103H123F17N30O11 — CID 159706090

IUPACbis(2-[1-[6-[6-amino-5-(difluoromethoxy)-3-pyridinyl]-2-[3-fluoro-3-(methoxymethyl)pyrrolidin-1-yl]pyrimidin-4-yl]-3-fluoropyrrolidin-3-yl]ethanol);3-(difluoromethoxy)-5-[2-(4,4-difluoropiperidin-1-yl)-6-[(1S,4S)-2-oxa-5-azabicyclo[2.2.1]heptan-5-yl]pyrimidin-4-yl]pyridin-2-amine;3-(difluoromethoxy)-5-[2-(3-fluoropiperidin-1-yl)-6-[(1S,4S)-2-oxa-5-azabicyclo[2.2.1]heptan-5-yl]pyrimidin-4-yl]pyridin-2-amine;3-fluoro-5-[2-(3-fluoro-3-methylpyrrolidin-1-yl)-6-[(1S,4S)-2-oxa-5-azabicyclo[2.2.1]heptan-5-yl]pyrimidin-4-yl]pyridin-2-amine
SMILESCC1(F)CCN(c2nc(-c3cnc(N)c(F)c3)cc(N3C[C@@H]4C[C@H]3CO4)n2)C1.COCC1(F)CCN(c2nc(-c3cnc(N)c(OC(F)F)c3)cc(N3CCC(F)(CCO)C3)n2)C1.COCC1(F)CCN(c2nc(-c3cnc(N)c(OC(F)F)c3)cc(N3CCC(F)(CCO)C3)n2)C1.Nc1ncc(-c2cc(N3C[C@@H]4C[C@H]3CO4)nc(N3CCC(F)(F)CC3)n2)cc1OC(F)F.Nc1ncc(-c2cc(N3C[C@@H]4C[C@H]3CO4)nc(N3CCCC(F)C3)n2)cc1OC(F)F
InChIInChI=1S/2C22H28F4N6O3.C20H22F4N6O2.C20H23F3N6O2.C19H22F2N6O/c2*1-34-13-22(26)3-6-32(12-22)20-29-15(14-8-16(35-19(23)24)18(27)28-10-14)9-17(30-20)31-5-2-21(25,11-31)4-7-33;21-18(22)32-15-5-11(8-26-17(15)25)14-7-16(30-9-13-6-12(30)10-31-13)28-19(27-14)29-3-1-20(23,24)2-4-29;21-12-2-1-3-28(8-12)20-26-15(11-4-16(31-19(22)23)18(24)25-7-11)6-17(27-20)29-9-14-5-13(29)10-30-14;1-19(21)2-3-26(10-19)18-24-15(11-4-14(20)17(22)23-7-11)6-16(25-18)27-8-13-5-12(27)9-28-13/h2*8-10,19,33H,2-7,11-13H2,1H3,(H2,27,28);5,7-8,12-13,18H,1-4,6,9-10H2,(H2,25,26);4,6-7,12-14,19H,1-3,5,8-10H2,(H2,24,25);4,6-7,12-13H,2-3,5,8-10H2,1H3,(H2,22,23)/t;;12-,13-;12?,13-,14-;12-,13-,19?/m..000/s1
InChIKeyMYFQHQLTMYPBSB-NRPULNDDSA-N
MW2280.28 g/mol
LogP12.92
Rot. Bonds31

About bis(2-[1-[6-[6-amino-5-(difluoromethoxy)-3-pyridinyl]-2-[3-fluoro-3-(methoxymethyl)pyrrolidin-1-yl]pyrimidin-4-yl]-3-fluoropyrrolidin-3-yl]ethanol);3-(difluoromethoxy)-5-[2-(4,4-difluoropiperidin-1-yl)-6-[(1S,4S)-2-oxa-5-azabicyclo[2.2.1]heptan-5-yl]pyrimidin-4-yl]pyridin-2-amine;3-(difluoromethoxy)-5-[2-(3-fluoropiperidin-1-yl)-6-[(1S,4S)-2-oxa-5-azabicyclo[2.2.1]heptan-5-yl]pyrimidin-4-yl]pyridin-2-amine;3-fluoro-5-[2-(3-fluoro-3-methylpyrrolidin-1-yl)-6-[(1S,4S)-2-oxa-5-azabicyclo[2.2.1]heptan-5-yl]pyrimidin-4-yl]pyridin-2-amine

bis(2-[1-[6-[6-amino-5-(difluoromethoxy)-3-pyridinyl]-2-[3-fluoro-3-(methoxymethyl)pyrrolidin-1-yl]pyrimidin-4-yl]-3-fluoropyrrolidin-3-yl]ethanol);3-(difluoromethoxy)-5-[2-(4,4-difluoropiperidin-1-yl)-6-[(1S,4S)-2-oxa-5-azabicyclo[2.2.1]heptan-5-yl]pyrimidin-4-yl]pyridin-2-amine;3-(difluoromethoxy)-5-[2-(3-fluoropiperidin-1-yl)-6-[(1S,4S)-2-oxa-5-azabicyclo[2.2.1]heptan-5-yl]pyrimidin-4-yl]pyridin-2-amine;3-fluoro-5-[2-(3-fluoro-3-methylpyrrolidin-1-yl)-6-[(1S,4S)-2-oxa-5-azabicyclo[2.2.1]heptan-5-yl]pyrimidin-4-yl]pyridin-2-amine (PubChem CID 159706090) has the molecular formula C103H123F17N30O11 and a molecular weight of 2280.28 g/mol. Its IUPAC name is bis(2-[1-[6-[6-amino-5-(difluoromethoxy)-3-pyridinyl]-2-[3-fluoro-3-(methoxymethyl)pyrrolidin-1-yl]pyrimidin-4-yl]-3-fluoropyrrolidin-3-yl]ethanol);3-(difluoromethoxy)-5-[2-(4,4-difluoropiperidin-1-yl)-6-[(1S,4S)-2-oxa-5-azabicyclo[2.2.1]heptan-5-yl]pyrimidin-4-yl]pyridin-2-amine;3-(difluoromethoxy)-5-[2-(3-fluoropiperidin-1-yl)-6-[(1S,4S)-2-oxa-5-azabicyclo[2.2.1]heptan-5-yl]pyrimidin-4-yl]pyridin-2-amine;3-fluoro-5-[2-(3-fluoro-3-methylpyrrolidin-1-yl)-6-[(1S,4S)-2-oxa-5-azabicyclo[2.2.1]heptan-5-yl]pyrimidin-4-yl]pyridin-2-amine.

Molecular Properties

Compound Namebis(2-[1-[6-[6-amino-5-(difluoromethoxy)-3-pyridinyl]-2-[3-fluoro-3-(methoxymethyl)pyrrolidin-1-yl]pyrimidin-4-yl]-3-fluoropyrrolidin-3-yl]ethanol);3-(difluoromethoxy)-5-[2-(4,4-difluoropiperidin-1-yl)-6-[(1S,4S)-2-oxa-5-azabicyclo[2.2.1]heptan-5-yl]pyrimidin-4-yl]pyridin-2-amine;3-(difluoromethoxy)-5-[2-(3-fluoropiperidin-1-yl)-6-[(1S,4S)-2-oxa-5-azabicyclo[2.2.1]heptan-5-yl]pyrimidin-4-yl]pyridin-2-amine;3-fluoro-5-[2-(3-fluoro-3-methylpyrrolidin-1-yl)-6-[(1S,4S)-2-oxa-5-azabicyclo[2.2.1]heptan-5-yl]pyrimidin-4-yl]pyridin-2-amine
PubChem CID159706090
Molecular FormulaC103H123F17N30O11
Molecular Weight2280.28 g/mol
Exact Mass2278.97
IUPAC Namebis(2-[1-[6-[6-amino-5-(difluoromethoxy)-3-pyridinyl]-2-[3-fluoro-3-(methoxymethyl)pyrrolidin-1-yl]pyrimidin-4-yl]-3-fluoropyrrolidin-3-yl]ethanol);3-(difluoromethoxy)-5-[2-(4,4-difluoropiperidin-1-yl)-6-[(1S,4S)-2-oxa-5-azabicyclo[2.2.1]heptan-5-yl]pyrimidin-4-yl]pyridin-2-amine;3-(difluoromethoxy)-5-[2-(3-fluoropiperidin-1-yl)-6-[(1S,4S)-2-oxa-5-azabicyclo[2.2.1]heptan-5-yl]pyrimidin-4-yl]pyridin-2-amine;3-fluoro-5-[2-(3-fluoro-3-methylpyrrolidin-1-yl)-6-[(1S,4S)-2-oxa-5-azabicyclo[2.2.1]heptan-5-yl]pyrimidin-4-yl]pyridin-2-amine
SMILESCC1(F)CCN(c2nc(-c3cnc(N)c(F)c3)cc(N3C[C@@H]4C[C@H]3CO4)n2)C1.COCC1(F)CCN(c2nc(-c3cnc(N)c(OC(F)F)c3)cc(N3CCC(F)(CCO)C3)n2)C1.COCC1(F)CCN(c2nc(-c3cnc(N)c(OC(F)F)c3)cc(N3CCC(F)(CCO)C3)n2)C1.Nc1ncc(-c2cc(N3C[C@@H]4C[C@H]3CO4)nc(N3CCC(F)(F)CC3)n2)cc1OC(F)F.Nc1ncc(-c2cc(N3C[C@@H]4C[C@H]3CO4)nc(N3CCCC(F)C3)n2)cc1OC(F)F
InChIInChI=1S/2C22H28F4N6O3.C20H22F4N6O2.C20H23F3N6O2.C19H22F2N6O/c2*1-34-13-22(26)3-6-32(12-22)20-29-15(14-8-16(35-19(23)24)18(27)28-10-14)9-17(30-20)31-5-2-21(25,11-31)4-7-33;21-18(22)32-15-5-11(8-26-17(15)25)14-7-16(30-9-13-6-12(30)10-31-13)28-19(27-14)29-3-1-20(23,24)2-4-29;21-12-2-1-3-28(8-12)20-26-15(11-4-16(31-19(22)23)18(24)25-7-11)6-17(27-20)29-9-14-5-13(29)10-30-14;1-19(21)2-3-26(10-19)18-24-15(11-4-14(20)17(22)23-7-11)6-16(25-18)27-8-13-5-12(27)9-28-13/h2*8-10,19,33H,2-7,11-13H2,1H3,(H2,27,28);5,7-8,12-13,18H,1-4,6,9-10H2,(H2,25,26);4,6-7,12-14,19H,1-3,5,8-10H2,(H2,24,25);4,6-7,12-13H,2-3,5,8-10H2,1H3,(H2,22,23)/t;;12-,13-;12?,13-,14-;12-,13-,19?/m..000/s1
InChIKeyMYFQHQLTMYPBSB-NRPULNDDSA-N
XLogP12.92
TPSA479.38 Ų
H-Bond Donors7
H-Bond Acceptors41
Rotatable Bonds31
Heavy Atoms161
Complexity—

Lipinski Rule of Five

4 violations

RuleValue
MW ≤ 5002280.28
LogP ≤ 512.92
H-Bond Donors ≤ 57
H-Bond Acceptors ≤ 1041

Analyze bis(2-[1-[6-[6-amino-5-(difluoromethoxy)-3-pyridinyl]-2-[3-fluoro-3-(methoxymethyl)pyrrolidin-1-yl]pyrimidin-4-yl]-3-fluoropyrrolidin-3-yl]ethanol);3-(difluoromethoxy)-5-[2-(4,4-difluoropiperidin-1-yl)-6-[(1S,4S)-2-oxa-5-azabicyclo[2.2.1]heptan-5-yl]pyrimidin-4-yl]pyridin-2-amine;3-(difluoromethoxy)-5-[2-(3-fluoropiperidin-1-yl)-6-[(1S,4S)-2-oxa-5-azabicyclo[2.2.1]heptan-5-yl]pyrimidin-4-yl]pyridin-2-amine;3-fluoro-5-[2-(3-fluoro-3-methylpyrrolidin-1-yl)-6-[(1S,4S)-2-oxa-5-azabicyclo[2.2.1]heptan-5-yl]pyrimidin-4-yl]pyridin-2-amine with MolForge

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Launch Full Analysis

Related Compounds

Gdc-0134
CID 86298636
5-[2-(2-azabicyclo[2.1.1]hexan-2-yl)-6-[(1S,4S)-2-oxa-5-azabicyclo[2.2.1]heptan-5-yl]pyrimidin-4-yl]-3-(difluoromethoxy)pyridin-2-amine
CID 117678371
3-(difluoromethoxy)-5-[2-[(3S)-3-fluoropyrrolidin-1-yl]-6-[(1S,4S)-2-oxa-5-azabicyclo[2.2.1]heptan-5-yl]pyrimidin-4-yl]pyridin-2-amine
CID 117678422
3-(difluoromethoxy)-5-[2-(3-fluoro-4-methylpyrrolidin-1-yl)-6-[(1S,4S)-2-oxa-5-azabicyclo[2.2.1]heptan-5-yl]pyrimidin-4-yl]pyridin-2-amine
CID 117688571
3-(difluoromethoxy)-5-[2-(3-fluoro-3-methylpyrrolidin-1-yl)-6-[(1S,4S)-2-oxa-5-azabicyclo[2.2.1]heptan-5-yl]pyrimidin-4-yl]pyridin-2-amine
CID 117688605
3-(difluoromethoxy)-5-[2-(3,3-difluoro-2-methylpyrrolidin-1-yl)-6-[(1S,4S)-2-oxa-5-azabicyclo[2.2.1]heptan-5-yl]pyrimidin-4-yl]pyridin-2-amine
CID 117688750
5-[2-[(1R,5S)-2-azabicyclo[3.1.0]hexan-2-yl]-6-[(1S,4S)-2-oxa-5-azabicyclo[2.2.1]heptan-5-yl]pyrimidin-4-yl]-3-(difluoromethoxy)pyridin-2-amine
CID 118876401
5-[2-(2-azabicyclo[2.1.1]hexan-2-yl)-6-[(1S,4S)-5-(2-methoxyethyl)-2,5-diazabicyclo[2.2.1]heptan-2-yl]pyrimidin-4-yl]-3-(difluoromethoxy)pyridin-2-amine
CID 118876433
5-[2-(2-azabicyclo[2.1.1]hexan-2-yl)-6-[(1S,4S)-2-oxa-5-azabicyclo[2.2.1]heptan-5-yl]pyrimidin-4-yl]-3-propan-2-yloxypyridin-2-amine
CID 86303388
5-[2-(2-azabicyclo[2.1.1]hexan-2-yl)-6-[(1S,4S)-2-oxa-5-azabicyclo[2.2.1]heptan-5-yl]pyrimidin-4-yl]-3-(trifluoromethoxy)pyridin-2-amine
CID 86303543
3-(difluoromethoxy)-5-[2-[(3S,4R)-3,4-difluoropyrrolidin-1-yl]-6-[(1S,4S)-2-oxa-5-azabicyclo[2.2.1]heptan-5-yl]pyrimidin-4-yl]pyridin-2-amine
CID 86304787
5-[2-(3,3-difluoroazetidin-1-yl)-6-[(1S,4S)-2-oxa-5-azabicyclo[2.2.1]heptan-5-yl]pyrimidin-4-yl]-3-(difluoromethoxy)pyridin-2-amine
CID 86304956

Frequently Asked Questions

What is the IUPAC name of bis(2-[1-[6-[6-amino-5-(difluoromethoxy)-3-pyridinyl]-2-[3-fluoro-3-(methoxymethyl)pyrrolidin-1-yl]pyrimidin-4-yl]-3-fluoropyrrolidin-3-yl]ethanol);3-(difluoromethoxy)-5-[2-(4,4-difluoropiperidin-1-yl)-6-[(1S,4S)-2-oxa-5-azabicyclo[2.2.1]heptan-5-yl]pyrimidin-4-yl]pyridin-2-amine;3-(difluoromethoxy)-5-[2-(3-fluoropiperidin-1-yl)-6-[(1S,4S)-2-oxa-5-azabicyclo[2.2.1]heptan-5-yl]pyrimidin-4-yl]pyridin-2-amine;3-fluoro-5-[2-(3-fluoro-3-methylpyrrolidin-1-yl)-6-[(1S,4S)-2-oxa-5-azabicyclo[2.2.1]heptan-5-yl]pyrimidin-4-yl]pyridin-2-amine?
The IUPAC name of bis(2-[1-[6-[6-amino-5-(difluoromethoxy)-3-pyridinyl]-2-[3-fluoro-3-(methoxymethyl)pyrrolidin-1-yl]pyrimidin-4-yl]-3-fluoropyrrolidin-3-yl]ethanol);3-(difluoromethoxy)-5-[2-(4,4-difluoropiperidin-1-yl)-6-[(1S,4S)-2-oxa-5-azabicyclo[2.2.1]heptan-5-yl]pyrimidin-4-yl]pyridin-2-amine;3-(difluoromethoxy)-5-[2-(3-fluoropiperidin-1-yl)-6-[(1S,4S)-2-oxa-5-azabicyclo[2.2.1]heptan-5-yl]pyrimidin-4-yl]pyridin-2-amine;3-fluoro-5-[2-(3-fluoro-3-methylpyrrolidin-1-yl)-6-[(1S,4S)-2-oxa-5-azabicyclo[2.2.1]heptan-5-yl]pyrimidin-4-yl]pyridin-2-amine (CID 159706090) is bis(2-[1-[6-[6-amino-5-(difluoromethoxy)-3-pyridinyl]-2-[3-fluoro-3-(methoxymethyl)pyrrolidin-1-yl]pyrimidin-4-yl]-3-fluoropyrrolidin-3-yl]ethanol);3-(difluoromethoxy)-5-[2-(4,4-difluoropiperidin-1-yl)-6-[(1S,4S)-2-oxa-5-azabicyclo[2.2.1]heptan-5-yl]pyrimidin-4-yl]pyridin-2-amine;3-(difluoromethoxy)-5-[2-(3-fluoropiperidin-1-yl)-6-[(1S,4S)-2-oxa-5-azabicyclo[2.2.1]heptan-5-yl]pyrimidin-4-yl]pyridin-2-amine;3-fluoro-5-[2-(3-fluoro-3-methylpyrrolidin-1-yl)-6-[(1S,4S)-2-oxa-5-azabicyclo[2.2.1]heptan-5-yl]pyrimidin-4-yl]pyridin-2-amine.
What is the SMILES notation for bis(2-[1-[6-[6-amino-5-(difluoromethoxy)-3-pyridinyl]-2-[3-fluoro-3-(methoxymethyl)pyrrolidin-1-yl]pyrimidin-4-yl]-3-fluoropyrrolidin-3-yl]ethanol);3-(difluoromethoxy)-5-[2-(4,4-difluoropiperidin-1-yl)-6-[(1S,4S)-2-oxa-5-azabicyclo[2.2.1]heptan-5-yl]pyrimidin-4-yl]pyridin-2-amine;3-(difluoromethoxy)-5-[2-(3-fluoropiperidin-1-yl)-6-[(1S,4S)-2-oxa-5-azabicyclo[2.2.1]heptan-5-yl]pyrimidin-4-yl]pyridin-2-amine;3-fluoro-5-[2-(3-fluoro-3-methylpyrrolidin-1-yl)-6-[(1S,4S)-2-oxa-5-azabicyclo[2.2.1]heptan-5-yl]pyrimidin-4-yl]pyridin-2-amine?
The canonical SMILES for bis(2-[1-[6-[6-amino-5-(difluoromethoxy)-3-pyridinyl]-2-[3-fluoro-3-(methoxymethyl)pyrrolidin-1-yl]pyrimidin-4-yl]-3-fluoropyrrolidin-3-yl]ethanol);3-(difluoromethoxy)-5-[2-(4,4-difluoropiperidin-1-yl)-6-[(1S,4S)-2-oxa-5-azabicyclo[2.2.1]heptan-5-yl]pyrimidin-4-yl]pyridin-2-amine;3-(difluoromethoxy)-5-[2-(3-fluoropiperidin-1-yl)-6-[(1S,4S)-2-oxa-5-azabicyclo[2.2.1]heptan-5-yl]pyrimidin-4-yl]pyridin-2-amine;3-fluoro-5-[2-(3-fluoro-3-methylpyrrolidin-1-yl)-6-[(1S,4S)-2-oxa-5-azabicyclo[2.2.1]heptan-5-yl]pyrimidin-4-yl]pyridin-2-amine is CC1(F)CCN(c2nc(-c3cnc(N)c(F)c3)cc(N3C[C@@H]4C[C@H]3CO4)n2)C1.COCC1(F)CCN(c2nc(-c3cnc(N)c(OC(F)F)c3)cc(N3CCC(F)(CCO)C3)n2)C1.COCC1(F)CCN(c2nc(-c3cnc(N)c(OC(F)F)c3)cc(N3CCC(F)(CCO)C3)n2)C1.Nc1ncc(-c2cc(N3C[C@@H]4C[C@H]3CO4)nc(N3CCC(F)(F)CC3)n2)cc1OC(F)F.Nc1ncc(-c2cc(N3C[C@@H]4C[C@H]3CO4)nc(N3CCCC(F)C3)n2)cc1OC(F)F.
What is the InChIKey of bis(2-[1-[6-[6-amino-5-(difluoromethoxy)-3-pyridinyl]-2-[3-fluoro-3-(methoxymethyl)pyrrolidin-1-yl]pyrimidin-4-yl]-3-fluoropyrrolidin-3-yl]ethanol);3-(difluoromethoxy)-5-[2-(4,4-difluoropiperidin-1-yl)-6-[(1S,4S)-2-oxa-5-azabicyclo[2.2.1]heptan-5-yl]pyrimidin-4-yl]pyridin-2-amine;3-(difluoromethoxy)-5-[2-(3-fluoropiperidin-1-yl)-6-[(1S,4S)-2-oxa-5-azabicyclo[2.2.1]heptan-5-yl]pyrimidin-4-yl]pyridin-2-amine;3-fluoro-5-[2-(3-fluoro-3-methylpyrrolidin-1-yl)-6-[(1S,4S)-2-oxa-5-azabicyclo[2.2.1]heptan-5-yl]pyrimidin-4-yl]pyridin-2-amine?
The InChIKey is MYFQHQLTMYPBSB-NRPULNDDSA-N. The full InChI is InChI=1S/2C22H28F4N6O3.C20H22F4N6O2.C20H23F3N6O2.C19H22F2N6O/c2*1-34-13-22(26)3-6-32(12-22)20-29-15(14-8-16(35-19(23)24)18(27)28-10-14)9-17(30-20)31-5-2-21(25,11-31)4-7-33;21-18(22)32-15-5-11(8-26-17(15)25)14-7-16(30-9-13-6-12(30)10-31-13)28-19(27-14)29-3-1-20(23,24)2-4-29;21-12-2-1-3-28(8-12)20-26-15(11-4-16(31-19(22)23)18(24)25-7-11)6-17(27-20)29-9-14-5-13(29)10-30-14;1-19(21)2-3-26(10-19)18-24-15(11-4-14(20)17(22)23-7-11)6-16(25-18)27-8-13-5-12(27)9-28-13/h2*8-10,19,33H,2-7,11-13H2,1H3,(H2,27,28);5,7-8,12-13,18H,1-4,6,9-10H2,(H2,25,26);4,6-7,12-14,19H,1-3,5,8-10H2,(H2,24,25);4,6-7,12-13H,2-3,5,8-10H2,1H3,(H2,22,23)/t;;12-,13-;12?,13-,14-;12-,13-,19?/m..000/s1.
What are the key properties of bis(2-[1-[6-[6-amino-5-(difluoromethoxy)-3-pyridinyl]-2-[3-fluoro-3-(methoxymethyl)pyrrolidin-1-yl]pyrimidin-4-yl]-3-fluoropyrrolidin-3-yl]ethanol);3-(difluoromethoxy)-5-[2-(4,4-difluoropiperidin-1-yl)-6-[(1S,4S)-2-oxa-5-azabicyclo[2.2.1]heptan-5-yl]pyrimidin-4-yl]pyridin-2-amine;3-(difluoromethoxy)-5-[2-(3-fluoropiperidin-1-yl)-6-[(1S,4S)-2-oxa-5-azabicyclo[2.2.1]heptan-5-yl]pyrimidin-4-yl]pyridin-2-amine;3-fluoro-5-[2-(3-fluoro-3-methylpyrrolidin-1-yl)-6-[(1S,4S)-2-oxa-5-azabicyclo[2.2.1]heptan-5-yl]pyrimidin-4-yl]pyridin-2-amine?
bis(2-[1-[6-[6-amino-5-(difluoromethoxy)-3-pyridinyl]-2-[3-fluoro-3-(methoxymethyl)pyrrolidin-1-yl]pyrimidin-4-yl]-3-fluoropyrrolidin-3-yl]ethanol);3-(difluoromethoxy)-5-[2-(4,4-difluoropiperidin-1-yl)-6-[(1S,4S)-2-oxa-5-azabicyclo[2.2.1]heptan-5-yl]pyrimidin-4-yl]pyridin-2-amine;3-(difluoromethoxy)-5-[2-(3-fluoropiperidin-1-yl)-6-[(1S,4S)-2-oxa-5-azabicyclo[2.2.1]heptan-5-yl]pyrimidin-4-yl]pyridin-2-amine;3-fluoro-5-[2-(3-fluoro-3-methylpyrrolidin-1-yl)-6-[(1S,4S)-2-oxa-5-azabicyclo[2.2.1]heptan-5-yl]pyrimidin-4-yl]pyridin-2-amine has a molecular weight of 2280.28 g/mol, XLogP of 12.92, 31 rotatable bonds, 7 hydrogen bond donors, and 41 hydrogen bond acceptors.
Where does this data come from?
All data for bis(2-[1-[6-[6-amino-5-(difluoromethoxy)-3-pyridinyl]-2-[3-fluoro-3-(methoxymethyl)pyrrolidin-1-yl]pyrimidin-4-yl]-3-fluoropyrrolidin-3-yl]ethanol);3-(difluoromethoxy)-5-[2-(4,4-difluoropiperidin-1-yl)-6-[(1S,4S)-2-oxa-5-azabicyclo[2.2.1]heptan-5-yl]pyrimidin-4-yl]pyridin-2-amine;3-(difluoromethoxy)-5-[2-(3-fluoropiperidin-1-yl)-6-[(1S,4S)-2-oxa-5-azabicyclo[2.2.1]heptan-5-yl]pyrimidin-4-yl]pyridin-2-amine;3-fluoro-5-[2-(3-fluoro-3-methylpyrrolidin-1-yl)-6-[(1S,4S)-2-oxa-5-azabicyclo[2.2.1]heptan-5-yl]pyrimidin-4-yl]pyridin-2-amine is sourced from PubChem (CID 159706090), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).