2-[3-methyl-4-(2-methyl-4-pyridinyl)phenyl]-N-(5-pyridin-2-yl-2-pyridinyl)acetamide;2-[4-(2-methyl-4-pyridinyl)phenyl]-N-(6-piperidin-1-yl-3-pyridinyl)acetamide;2-(3-methyl-4-pyridin-3-ylphenyl)-N-(5-pyridin-2-yl-2-pyridinyl)acetamide;2-[4-(2-methyl-4-pyridinyl)phenyl]-N-(5-pyridin-3-yl-2-pyridinyl)acetamide;2-[4-(2-methyl-4-pyridinyl)-3-(trifluoromethyl)phenyl]-N-(5-pyrazin-2-yl-2-pyridinyl)acetamide

C121H106F3N21O5 — CID 159706389

IUPAC2-[3-methyl-4-(2-methyl-4-pyridinyl)phenyl]-N-(5-pyridin-2-yl-2-pyridinyl)acetamide;2-[4-(2-methyl-4-pyridinyl)phenyl]-N-(6-piperidin-1-yl-3-pyridinyl)acetamide;2-(3-methyl-4-pyridin-3-ylphenyl)-N-(5-pyridin-2-yl-2-pyridinyl)acetamide;2-[4-(2-methyl-4-pyridinyl)phenyl]-N-(5-pyridin-3-yl-2-pyridinyl)acetamide;2-[4-(2-methyl-4-pyridinyl)-3-(trifluoromethyl)phenyl]-N-(5-pyrazin-2-yl-2-pyridinyl)acetamide
SMILESCc1cc(-c2ccc(CC(=O)Nc3ccc(-c4ccccn4)cn3)cc2C)ccn1.Cc1cc(-c2ccc(CC(=O)Nc3ccc(-c4cccnc4)cn3)cc2)ccn1.Cc1cc(-c2ccc(CC(=O)Nc3ccc(-c4cnccn4)cn3)cc2C(F)(F)F)ccn1.Cc1cc(-c2ccc(CC(=O)Nc3ccc(N4CCCCC4)nc3)cc2)ccn1.Cc1cc(CC(=O)Nc2ccc(-c3ccccn3)cn2)ccc1-c1cccnc1
InChIInChI=1S/C25H22N4O.C24H18F3N5O.2C24H20N4O.C24H26N4O/c1-17-13-19(6-8-22(17)20-10-12-26-18(2)14-20)15-25(30)29-24-9-7-21(16-28-24)23-5-3-4-11-27-23;1-15-10-17(6-7-29-15)19-4-2-16(11-20(19)24(25,26)27)12-23(33)32-22-5-3-18(13-31-22)21-14-28-8-9-30-21;1-17-13-20(10-12-26-17)19-6-4-18(5-7-19)14-24(29)28-23-9-8-22(16-27-23)21-3-2-11-25-15-21;1-17-13-18(7-9-21(17)19-5-4-11-25-15-19)14-24(29)28-23-10-8-20(16-27-23)22-6-2-3-12-26-22;1-18-15-21(11-12-25-18)20-7-5-19(6-8-20)16-24(29)27-22-9-10-23(26-17-22)28-13-3-2-4-14-28/h3-14,16H,15H2,1-2H3,(H,28,29,30);2-11,13-14H,12H2,1H3,(H,31,32,33);2*2-13,15-16H,14H2,1H3,(H,27,28,29);5-12,15,17H,2-4,13-14,16H2,1H3,(H,27,29)
InChIKeyMYGPLJKGSCLSQT-UHFFFAOYSA-N
MW1991.31 g/mol
LogP24.13
Rot. Bonds25

About 2-[3-methyl-4-(2-methyl-4-pyridinyl)phenyl]-N-(5-pyridin-2-yl-2-pyridinyl)acetamide;2-[4-(2-methyl-4-pyridinyl)phenyl]-N-(6-piperidin-1-yl-3-pyridinyl)acetamide;2-(3-methyl-4-pyridin-3-ylphenyl)-N-(5-pyridin-2-yl-2-pyridinyl)acetamide;2-[4-(2-methyl-4-pyridinyl)phenyl]-N-(5-pyridin-3-yl-2-pyridinyl)acetamide;2-[4-(2-methyl-4-pyridinyl)-3-(trifluoromethyl)phenyl]-N-(5-pyrazin-2-yl-2-pyridinyl)acetamide

2-[3-methyl-4-(2-methyl-4-pyridinyl)phenyl]-N-(5-pyridin-2-yl-2-pyridinyl)acetamide;2-[4-(2-methyl-4-pyridinyl)phenyl]-N-(6-piperidin-1-yl-3-pyridinyl)acetamide;2-(3-methyl-4-pyridin-3-ylphenyl)-N-(5-pyridin-2-yl-2-pyridinyl)acetamide;2-[4-(2-methyl-4-pyridinyl)phenyl]-N-(5-pyridin-3-yl-2-pyridinyl)acetamide;2-[4-(2-methyl-4-pyridinyl)-3-(trifluoromethyl)phenyl]-N-(5-pyrazin-2-yl-2-pyridinyl)acetamide (PubChem CID 159706389) has the molecular formula C121H106F3N21O5 and a molecular weight of 1991.31 g/mol. Its IUPAC name is 2-[3-methyl-4-(2-methyl-4-pyridinyl)phenyl]-N-(5-pyridin-2-yl-2-pyridinyl)acetamide;2-[4-(2-methyl-4-pyridinyl)phenyl]-N-(6-piperidin-1-yl-3-pyridinyl)acetamide;2-(3-methyl-4-pyridin-3-ylphenyl)-N-(5-pyridin-2-yl-2-pyridinyl)acetamide;2-[4-(2-methyl-4-pyridinyl)phenyl]-N-(5-pyridin-3-yl-2-pyridinyl)acetamide;2-[4-(2-methyl-4-pyridinyl)-3-(trifluoromethyl)phenyl]-N-(5-pyrazin-2-yl-2-pyridinyl)acetamide.

Molecular Properties

Compound Name2-[3-methyl-4-(2-methyl-4-pyridinyl)phenyl]-N-(5-pyridin-2-yl-2-pyridinyl)acetamide;2-[4-(2-methyl-4-pyridinyl)phenyl]-N-(6-piperidin-1-yl-3-pyridinyl)acetamide;2-(3-methyl-4-pyridin-3-ylphenyl)-N-(5-pyridin-2-yl-2-pyridinyl)acetamide;2-[4-(2-methyl-4-pyridinyl)phenyl]-N-(5-pyridin-3-yl-2-pyridinyl)acetamide;2-[4-(2-methyl-4-pyridinyl)-3-(trifluoromethyl)phenyl]-N-(5-pyrazin-2-yl-2-pyridinyl)acetamide
PubChem CID159706389
Molecular FormulaC121H106F3N21O5
Molecular Weight1991.31 g/mol
Exact Mass1989.86
IUPAC Name2-[3-methyl-4-(2-methyl-4-pyridinyl)phenyl]-N-(5-pyridin-2-yl-2-pyridinyl)acetamide;2-[4-(2-methyl-4-pyridinyl)phenyl]-N-(6-piperidin-1-yl-3-pyridinyl)acetamide;2-(3-methyl-4-pyridin-3-ylphenyl)-N-(5-pyridin-2-yl-2-pyridinyl)acetamide;2-[4-(2-methyl-4-pyridinyl)phenyl]-N-(5-pyridin-3-yl-2-pyridinyl)acetamide;2-[4-(2-methyl-4-pyridinyl)-3-(trifluoromethyl)phenyl]-N-(5-pyrazin-2-yl-2-pyridinyl)acetamide
SMILESCc1cc(-c2ccc(CC(=O)Nc3ccc(-c4ccccn4)cn3)cc2C)ccn1.Cc1cc(-c2ccc(CC(=O)Nc3ccc(-c4cccnc4)cn3)cc2)ccn1.Cc1cc(-c2ccc(CC(=O)Nc3ccc(-c4cnccn4)cn3)cc2C(F)(F)F)ccn1.Cc1cc(-c2ccc(CC(=O)Nc3ccc(N4CCCCC4)nc3)cc2)ccn1.Cc1cc(CC(=O)Nc2ccc(-c3ccccn3)cn2)ccc1-c1cccnc1
InChIInChI=1S/C25H22N4O.C24H18F3N5O.2C24H20N4O.C24H26N4O/c1-17-13-19(6-8-22(17)20-10-12-26-18(2)14-20)15-25(30)29-24-9-7-21(16-28-24)23-5-3-4-11-27-23;1-15-10-17(6-7-29-15)19-4-2-16(11-20(19)24(25,26)27)12-23(33)32-22-5-3-18(13-31-22)21-14-28-8-9-30-21;1-17-13-20(10-12-26-17)19-6-4-18(5-7-19)14-24(29)28-23-9-8-22(16-27-23)21-3-2-11-25-15-21;1-17-13-18(7-9-21(17)19-5-4-11-25-15-19)14-24(29)28-23-10-8-20(16-27-23)22-6-2-3-12-26-22;1-18-15-21(11-12-25-18)20-7-5-19(6-8-20)16-24(29)27-22-9-10-23(26-17-22)28-13-3-2-4-14-28/h3-14,16H,15H2,1-2H3,(H,28,29,30);2-11,13-14H,12H2,1H3,(H,31,32,33);2*2-13,15-16H,14H2,1H3,(H,27,28,29);5-12,15,17H,2-4,13-14,16H2,1H3,(H,27,29)
InChIKeyMYGPLJKGSCLSQT-UHFFFAOYSA-N
XLogP24.13
TPSA342.09 Ų
H-Bond Donors5
H-Bond Acceptors21
Rotatable Bonds25
Heavy Atoms150
Complexity—

Lipinski Rule of Five

3 violations

RuleValue
MW ≤ 5001991.31
LogP ≤ 524.13
H-Bond Donors ≤ 55
H-Bond Acceptors ≤ 1021

Analyze 2-[3-methyl-4-(2-methyl-4-pyridinyl)phenyl]-N-(5-pyridin-2-yl-2-pyridinyl)acetamide;2-[4-(2-methyl-4-pyridinyl)phenyl]-N-(6-piperidin-1-yl-3-pyridinyl)acetamide;2-(3-methyl-4-pyridin-3-ylphenyl)-N-(5-pyridin-2-yl-2-pyridinyl)acetamide;2-[4-(2-methyl-4-pyridinyl)phenyl]-N-(5-pyridin-3-yl-2-pyridinyl)acetamide;2-[4-(2-methyl-4-pyridinyl)-3-(trifluoromethyl)phenyl]-N-(5-pyrazin-2-yl-2-pyridinyl)acetamide with MolForge

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Related Compounds

Wnt-974
CID 46926973
Flumatinib
CID 46848036
Gnf6231
CID 46927297
US10251893, Cpd 128
CID 46927133
N-(5-(4-Acetylpiperazin-1-yl)pyridin-2-yl)-2-(2',3-dimethyl-[2,4'-bipyridin]-5-yl)acetamide
CID 46927217
2'-Fluoro-3-methyl-N-[5-(2-pyrazinyl)-2-pyridinyl][2,4'-bipyridine]-5-acetamide
CID 46927364
Flumatinib Mesylate
CID 46910592
2-[5-methyl-6-(6-methyl-3-pyridinyl)-3-pyridinyl]-N-(5-pyrazin-2-yl-2-pyridinyl)acetamide
CID 121237481
3-[4-(2-methyl-4-pyridinyl)phenyl]-N-(5-pyrazin-2-yl-2-pyridinyl)propanamide
CID 122192867
N-[2-(2-piperazin-1-yl-4-pyridinyl)-6-(pyrazin-2-ylamino)-4-pyridinyl]-2-pyridin-3-ylacetamide
CID 67128018
N-(5-(4-acetylpiperazin-1-yl)pyridin-2-yl)-2-(2-fluoro-5-methyl-4-(2-methylpyridin-4-yl)phenyl)acetamide
CID 46871751
US10251893, Cpd 189
CID 46927295

Frequently Asked Questions

What is the IUPAC name of 2-[3-methyl-4-(2-methyl-4-pyridinyl)phenyl]-N-(5-pyridin-2-yl-2-pyridinyl)acetamide;2-[4-(2-methyl-4-pyridinyl)phenyl]-N-(6-piperidin-1-yl-3-pyridinyl)acetamide;2-(3-methyl-4-pyridin-3-ylphenyl)-N-(5-pyridin-2-yl-2-pyridinyl)acetamide;2-[4-(2-methyl-4-pyridinyl)phenyl]-N-(5-pyridin-3-yl-2-pyridinyl)acetamide;2-[4-(2-methyl-4-pyridinyl)-3-(trifluoromethyl)phenyl]-N-(5-pyrazin-2-yl-2-pyridinyl)acetamide?
The IUPAC name of 2-[3-methyl-4-(2-methyl-4-pyridinyl)phenyl]-N-(5-pyridin-2-yl-2-pyridinyl)acetamide;2-[4-(2-methyl-4-pyridinyl)phenyl]-N-(6-piperidin-1-yl-3-pyridinyl)acetamide;2-(3-methyl-4-pyridin-3-ylphenyl)-N-(5-pyridin-2-yl-2-pyridinyl)acetamide;2-[4-(2-methyl-4-pyridinyl)phenyl]-N-(5-pyridin-3-yl-2-pyridinyl)acetamide;2-[4-(2-methyl-4-pyridinyl)-3-(trifluoromethyl)phenyl]-N-(5-pyrazin-2-yl-2-pyridinyl)acetamide (CID 159706389) is 2-[3-methyl-4-(2-methyl-4-pyridinyl)phenyl]-N-(5-pyridin-2-yl-2-pyridinyl)acetamide;2-[4-(2-methyl-4-pyridinyl)phenyl]-N-(6-piperidin-1-yl-3-pyridinyl)acetamide;2-(3-methyl-4-pyridin-3-ylphenyl)-N-(5-pyridin-2-yl-2-pyridinyl)acetamide;2-[4-(2-methyl-4-pyridinyl)phenyl]-N-(5-pyridin-3-yl-2-pyridinyl)acetamide;2-[4-(2-methyl-4-pyridinyl)-3-(trifluoromethyl)phenyl]-N-(5-pyrazin-2-yl-2-pyridinyl)acetamide.
What is the SMILES notation for 2-[3-methyl-4-(2-methyl-4-pyridinyl)phenyl]-N-(5-pyridin-2-yl-2-pyridinyl)acetamide;2-[4-(2-methyl-4-pyridinyl)phenyl]-N-(6-piperidin-1-yl-3-pyridinyl)acetamide;2-(3-methyl-4-pyridin-3-ylphenyl)-N-(5-pyridin-2-yl-2-pyridinyl)acetamide;2-[4-(2-methyl-4-pyridinyl)phenyl]-N-(5-pyridin-3-yl-2-pyridinyl)acetamide;2-[4-(2-methyl-4-pyridinyl)-3-(trifluoromethyl)phenyl]-N-(5-pyrazin-2-yl-2-pyridinyl)acetamide?
The canonical SMILES for 2-[3-methyl-4-(2-methyl-4-pyridinyl)phenyl]-N-(5-pyridin-2-yl-2-pyridinyl)acetamide;2-[4-(2-methyl-4-pyridinyl)phenyl]-N-(6-piperidin-1-yl-3-pyridinyl)acetamide;2-(3-methyl-4-pyridin-3-ylphenyl)-N-(5-pyridin-2-yl-2-pyridinyl)acetamide;2-[4-(2-methyl-4-pyridinyl)phenyl]-N-(5-pyridin-3-yl-2-pyridinyl)acetamide;2-[4-(2-methyl-4-pyridinyl)-3-(trifluoromethyl)phenyl]-N-(5-pyrazin-2-yl-2-pyridinyl)acetamide is Cc1cc(-c2ccc(CC(=O)Nc3ccc(-c4ccccn4)cn3)cc2C)ccn1.Cc1cc(-c2ccc(CC(=O)Nc3ccc(-c4cccnc4)cn3)cc2)ccn1.Cc1cc(-c2ccc(CC(=O)Nc3ccc(-c4cnccn4)cn3)cc2C(F)(F)F)ccn1.Cc1cc(-c2ccc(CC(=O)Nc3ccc(N4CCCCC4)nc3)cc2)ccn1.Cc1cc(CC(=O)Nc2ccc(-c3ccccn3)cn2)ccc1-c1cccnc1.
What is the InChIKey of 2-[3-methyl-4-(2-methyl-4-pyridinyl)phenyl]-N-(5-pyridin-2-yl-2-pyridinyl)acetamide;2-[4-(2-methyl-4-pyridinyl)phenyl]-N-(6-piperidin-1-yl-3-pyridinyl)acetamide;2-(3-methyl-4-pyridin-3-ylphenyl)-N-(5-pyridin-2-yl-2-pyridinyl)acetamide;2-[4-(2-methyl-4-pyridinyl)phenyl]-N-(5-pyridin-3-yl-2-pyridinyl)acetamide;2-[4-(2-methyl-4-pyridinyl)-3-(trifluoromethyl)phenyl]-N-(5-pyrazin-2-yl-2-pyridinyl)acetamide?
The InChIKey is MYGPLJKGSCLSQT-UHFFFAOYSA-N. The full InChI is InChI=1S/C25H22N4O.C24H18F3N5O.2C24H20N4O.C24H26N4O/c1-17-13-19(6-8-22(17)20-10-12-26-18(2)14-20)15-25(30)29-24-9-7-21(16-28-24)23-5-3-4-11-27-23;1-15-10-17(6-7-29-15)19-4-2-16(11-20(19)24(25,26)27)12-23(33)32-22-5-3-18(13-31-22)21-14-28-8-9-30-21;1-17-13-20(10-12-26-17)19-6-4-18(5-7-19)14-24(29)28-23-9-8-22(16-27-23)21-3-2-11-25-15-21;1-17-13-18(7-9-21(17)19-5-4-11-25-15-19)14-24(29)28-23-10-8-20(16-27-23)22-6-2-3-12-26-22;1-18-15-21(11-12-25-18)20-7-5-19(6-8-20)16-24(29)27-22-9-10-23(26-17-22)28-13-3-2-4-14-28/h3-14,16H,15H2,1-2H3,(H,28,29,30);2-11,13-14H,12H2,1H3,(H,31,32,33);2*2-13,15-16H,14H2,1H3,(H,27,28,29);5-12,15,17H,2-4,13-14,16H2,1H3,(H,27,29).
What are the key properties of 2-[3-methyl-4-(2-methyl-4-pyridinyl)phenyl]-N-(5-pyridin-2-yl-2-pyridinyl)acetamide;2-[4-(2-methyl-4-pyridinyl)phenyl]-N-(6-piperidin-1-yl-3-pyridinyl)acetamide;2-(3-methyl-4-pyridin-3-ylphenyl)-N-(5-pyridin-2-yl-2-pyridinyl)acetamide;2-[4-(2-methyl-4-pyridinyl)phenyl]-N-(5-pyridin-3-yl-2-pyridinyl)acetamide;2-[4-(2-methyl-4-pyridinyl)-3-(trifluoromethyl)phenyl]-N-(5-pyrazin-2-yl-2-pyridinyl)acetamide?
2-[3-methyl-4-(2-methyl-4-pyridinyl)phenyl]-N-(5-pyridin-2-yl-2-pyridinyl)acetamide;2-[4-(2-methyl-4-pyridinyl)phenyl]-N-(6-piperidin-1-yl-3-pyridinyl)acetamide;2-(3-methyl-4-pyridin-3-ylphenyl)-N-(5-pyridin-2-yl-2-pyridinyl)acetamide;2-[4-(2-methyl-4-pyridinyl)phenyl]-N-(5-pyridin-3-yl-2-pyridinyl)acetamide;2-[4-(2-methyl-4-pyridinyl)-3-(trifluoromethyl)phenyl]-N-(5-pyrazin-2-yl-2-pyridinyl)acetamide has a molecular weight of 1991.31 g/mol, XLogP of 24.13, 25 rotatable bonds, 5 hydrogen bond donors, and 21 hydrogen bond acceptors.
Where does this data come from?
All data for 2-[3-methyl-4-(2-methyl-4-pyridinyl)phenyl]-N-(5-pyridin-2-yl-2-pyridinyl)acetamide;2-[4-(2-methyl-4-pyridinyl)phenyl]-N-(6-piperidin-1-yl-3-pyridinyl)acetamide;2-(3-methyl-4-pyridin-3-ylphenyl)-N-(5-pyridin-2-yl-2-pyridinyl)acetamide;2-[4-(2-methyl-4-pyridinyl)phenyl]-N-(5-pyridin-3-yl-2-pyridinyl)acetamide;2-[4-(2-methyl-4-pyridinyl)-3-(trifluoromethyl)phenyl]-N-(5-pyrazin-2-yl-2-pyridinyl)acetamide is sourced from PubChem (CID 159706389), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).