(3R)-3-[5-(6-amino-3-pyridinyl)furo[3,2-b]pyridin-2-yl]-3-[(4-fluoro-5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]pyrrolidine-2,5-dione;(3R)-3-[(4-fluoro-5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]-3-[5-[(1-methylpiperidin-4-yl)-(2H-pyrrol-4-yl)amino]furo[3,2-b]pyridin-2-yl]pyrrolidine-2,5-dione;(3R)-3-[(4-fluoro-5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]-3-[5-(2-piperazin-1-yl-4-pyridinyl)furo[3,2-b]pyridin-2-yl]pyrrolidine-2,5-dione;(3R)-3-[(4-fluoro-5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]-3-[5-[2-[4-(2,2,2-trifluoroacetyl)piperazin-1-yl]-4-pyridinyl]furo[3,2-b]pyridin-2-yl]pyrrolidine-2,5-dione

C119H104F7N23O21 — CID 159710349

About (3R)-3-[5-(6-amino-3-pyridinyl)furo[3,2-b]pyridin-2-yl]-3-[(4-fluoro-5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]pyrrolidine-2,5-dione;(3R)-3-[(4-fluoro-5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]-3-[5-[(1-methylpiperidin-4-yl)-(2H-pyrrol-4-yl)amino]furo[3,2-b]pyridin-2-yl]pyrrolidine-2,5-dione;(3R)-3-[(4-fluoro-5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]-3-[5-(2-piperazin-1-yl-4-pyridinyl)furo[3,2-b]pyridin-2-yl]pyrrolidine-2,5-dione;(3R)-3-[(4-fluoro-5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]-3-[5-[2-[4-(2,2,2-trifluoroacetyl)piperazin-1-yl]-4-pyridinyl]furo[3,2-b]pyridin-2-yl]pyrrolidine-2,5-dione

(3R)-3-[5-(6-amino-3-pyridinyl)furo[3,2-b]pyridin-2-yl]-3-[(4-fluoro-5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]pyrrolidine-2,5-dione;(3R)-3-[(4-fluoro-5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]-3-[5-[(1-methylpiperidin-4-yl)-(2H-pyrrol-4-yl)amino]furo[3,2-b]pyridin-2-yl]pyrrolidine-2,5-dione;(3R)-3-[(4-fluoro-5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]-3-[5-(2-piperazin-1-yl-4-pyridinyl)furo[3,2-b]pyridin-2-yl]pyrrolidine-2,5-dione;(3R)-3-[(4-fluoro-5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]-3-[5-[2-[4-(2,2,2-trifluoroacetyl)piperazin-1-yl]-4-pyridinyl]furo[3,2-b]pyridin-2-yl]pyrrolidine-2,5-dione (PubChem CID 159710349) has the molecular formula C119H104F7N23O21 and a molecular weight of 2325.27 g/mol. Its IUPAC name is (3R)-3-[5-(6-amino-3-pyridinyl)furo[3,2-b]pyridin-2-yl]-3-[(4-fluoro-5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]pyrrolidine-2,5-dione;(3R)-3-[(4-fluoro-5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]-3-[5-[(1-methylpiperidin-4-yl)-(2H-pyrrol-4-yl)amino]furo[3,2-b]pyridin-2-yl]pyrrolidine-2,5-dione;(3R)-3-[(4-fluoro-5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]-3-[5-(2-piperazin-1-yl-4-pyridinyl)furo[3,2-b]pyridin-2-yl]pyrrolidine-2,5-dione;(3R)-3-[(4-fluoro-5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]-3-[5-[2-[4-(2,2,2-trifluoroacetyl)piperazin-1-yl]-4-pyridinyl]furo[3,2-b]pyridin-2-yl]pyrrolidine-2,5-dione.

Molecular Properties

• Compound Name: (3R)-3-[5-(6-amino-3-pyridinyl)furo[3,2-b]pyridin-2-yl]-3-[(4-fluoro-5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]pyrrolidine-2,5-dione;(3R)-3-[(4-fluoro-5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]-3-[5-[(1-methylpiperidin-4-yl)-(2H-pyrrol-4-yl)amino]furo[3,2-b]pyridin-2-yl]pyrrolidine-2,5-dione;(3R)-3-[(4-fluoro-5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]-3-[5-(2-piperazin-1-yl-4-pyridinyl)furo[3,2-b]pyridin-2-yl]pyrrolidine-2,5-dione;(3R)-3-[(4-fluoro-5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]-3-[5-[2-[4-(2,2,2-trifluoroacetyl)piperazin-1-yl]-4-pyridinyl]furo[3,2-b]pyridin-2-yl]pyrrolidine-2,5-dione
• PubChem CID: 159710349
• Molecular Formula: C119H104F7N23O21
• Molecular Weight: 2325.27 g/mol
• Exact Mass: 2323.77
• IUPAC Name: (3R)-3-[5-(6-amino-3-pyridinyl)furo[3,2-b]pyridin-2-yl]-3-[(4-fluoro-5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]pyrrolidine-2,5-dione;(3R)-3-[(4-fluoro-5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]-3-[5-[(1-methylpiperidin-4-yl)-(2H-pyrrol-4-yl)amino]furo[3,2-b]pyridin-2-yl]pyrrolidine-2,5-dione;(3R)-3-[(4-fluoro-5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]-3-[5-(2-piperazin-1-yl-4-pyridinyl)furo[3,2-b]pyridin-2-yl]pyrrolidine-2,5-dione;(3R)-3-[(4-fluoro-5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]-3-[5-[2-[4-(2,2,2-trifluoroacetyl)piperazin-1-yl]-4-pyridinyl]furo[3,2-b]pyridin-2-yl]pyrrolidine-2,5-dione
• SMILES: COc1ccc2c(c1F)C(=O)N(C[C@@]1(c3cc4nc(-c5ccc(N)nc5)ccc4o3)CC(=O)NC1=O)C2.COc1ccc2c(c1F)C(=O)N(C[C@@]1(c3cc4nc(-c5ccnc(N6CCN(C(=O)C(F)(F)F)CC6)c5)ccc4o3)CC(=O)NC1=O)C2.COc1ccc2c(c1F)C(=O)N(C[C@@]1(c3cc4nc(-c5ccnc(N6CCNCC6)c5)ccc4o3)CC(=O)NC1=O)C2.COc1ccc2c(c1F)C(=O)N(C[C@@]1(c3cc4nc(N(C5=CCN=C5)C5CCN(C)CC5)ccc4o3)CC(=O)NC1=O)C2
• InChI: InChI=1S/C32H26F4N6O6.C31H31FN6O5.C30H27FN6O5.C26H20FN5O5/c1-47-22-4-2-18-15-42(28(44)26(18)27(22)33)16-31(14-25(43)39-29(31)45)23-13-20-21(48-23)5-3-19(38-20)17-6-7-37-24(12-17)40-8-10-41(11-9-40)30(46)32(34,35)36;1-36-11-8-19(9-12-36)38(20-7-10-33-15-20)25-6-5-22-21(34-25)13-24(43-22)31(14-26(39)35-30(31)41)17-37-16-18-3-4-23(42-2)28(32)27(18)29(37)40;1-41-22-4-2-18-15-37(28(39)26(18)27(22)31)16-30(14-25(38)35-29(30)40)23-13-20-21(42-23)5-3-19(34-20)17-6-7-33-24(12-17)36-10-8-32-9-11-36;1-36-18-5-2-14-11-32(24(34)22(14)23(18)27)12-26(9-21(33)31-25(26)35)19-8-16-17(37-19)6-4-15(30-16)13-3-7-20(28)29-10-13/h2-7,12-13H,8-11,14-16H2,1H3,(H,39,43,45);3-7,13,15,19H,8-12,14,16-17H2,1-2H3,(H,35,39,41);2-7,12-13,32H,8-11,14-16H2,1H3,(H,35,38,40);2-8,10H,9,11-12H2,1H3,(H2,28,29)(H,31,33,35)/t2*31-;30-;26-/m1111/s1
• InChIKey: MYTHWIWRQSXRFP-UBBDELJFSA-N
• XLogP: 10.92
• TPSA: 529.31 Ų
• H-Bond Donors: 6
• H-Bond Acceptors: 35
• Rotatable Bonds: 24
• Heavy Atoms: 170
• Complexity: —

Lipinski Rule of Five

4 violations

Rule	Value
MW ≤ 500	2325.27
LogP ≤ 5	10.92
H-Bond Donors ≤ 5	6
H-Bond Acceptors ≤ 10	35

Computed Properties (RDKit)

• Structural Alerts: {'alert_name': 'phthalimide', 'substructure': 'N/A'}

Frequently Asked Questions

What is the IUPAC name of (3R)-3-[5-(6-amino-3-pyridinyl)furo[3,2-b]pyridin-2-yl]-3-[(4-fluoro-5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]pyrrolidine-2,5-dione;(3R)-3-[(4-fluoro-5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]-3-[5-[(1-methylpiperidin-4-yl)-(2H-pyrrol-4-yl)amino]furo[3,2-b]pyridin-2-yl]pyrrolidine-2,5-dione;(3R)-3-[(4-fluoro-5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]-3-[5-(2-piperazin-1-yl-4-pyridinyl)furo[3,2-b]pyridin-2-yl]pyrrolidine-2,5-dione;(3R)-3-[(4-fluoro-5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]-3-[5-[2-[4-(2,2,2-trifluoroacetyl)piperazin-1-yl]-4-pyridinyl]furo[3,2-b]pyridin-2-yl]pyrrolidine-2,5-dione?

The IUPAC name of (3R)-3-[5-(6-amino-3-pyridinyl)furo[3,2-b]pyridin-2-yl]-3-[(4-fluoro-5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]pyrrolidine-2,5-dione;(3R)-3-[(4-fluoro-5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]-3-[5-[(1-methylpiperidin-4-yl)-(2H-pyrrol-4-yl)amino]furo[3,2-b]pyridin-2-yl]pyrrolidine-2,5-dione;(3R)-3-[(4-fluoro-5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]-3-[5-(2-piperazin-1-yl-4-pyridinyl)furo[3,2-b]pyridin-2-yl]pyrrolidine-2,5-dione;(3R)-3-[(4-fluoro-5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]-3-[5-[2-[4-(2,2,2-trifluoroacetyl)piperazin-1-yl]-4-pyridinyl]furo[3,2-b]pyridin-2-yl]pyrrolidine-2,5-dione (CID 159710349) is (3R)-3-[5-(6-amino-3-pyridinyl)furo[3,2-b]pyridin-2-yl]-3-[(4-fluoro-5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]pyrrolidine-2,5-dione;(3R)-3-[(4-fluoro-5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]-3-[5-[(1-methylpiperidin-4-yl)-(2H-pyrrol-4-yl)amino]furo[3,2-b]pyridin-2-yl]pyrrolidine-2,5-dione;(3R)-3-[(4-fluoro-5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]-3-[5-(2-piperazin-1-yl-4-pyridinyl)furo[3,2-b]pyridin-2-yl]pyrrolidine-2,5-dione;(3R)-3-[(4-fluoro-5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]-3-[5-[2-[4-(2,2,2-trifluoroacetyl)piperazin-1-yl]-4-pyridinyl]furo[3,2-b]pyridin-2-yl]pyrrolidine-2,5-dione.

What is the SMILES notation for (3R)-3-[5-(6-amino-3-pyridinyl)furo[3,2-b]pyridin-2-yl]-3-[(4-fluoro-5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]pyrrolidine-2,5-dione;(3R)-3-[(4-fluoro-5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]-3-[5-[(1-methylpiperidin-4-yl)-(2H-pyrrol-4-yl)amino]furo[3,2-b]pyridin-2-yl]pyrrolidine-2,5-dione;(3R)-3-[(4-fluoro-5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]-3-[5-(2-piperazin-1-yl-4-pyridinyl)furo[3,2-b]pyridin-2-yl]pyrrolidine-2,5-dione;(3R)-3-[(4-fluoro-5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]-3-[5-[2-[4-(2,2,2-trifluoroacetyl)piperazin-1-yl]-4-pyridinyl]furo[3,2-b]pyridin-2-yl]pyrrolidine-2,5-dione?

The canonical SMILES for (3R)-3-[5-(6-amino-3-pyridinyl)furo[3,2-b]pyridin-2-yl]-3-[(4-fluoro-5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]pyrrolidine-2,5-dione;(3R)-3-[(4-fluoro-5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]-3-[5-[(1-methylpiperidin-4-yl)-(2H-pyrrol-4-yl)amino]furo[3,2-b]pyridin-2-yl]pyrrolidine-2,5-dione;(3R)-3-[(4-fluoro-5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]-3-[5-(2-piperazin-1-yl-4-pyridinyl)furo[3,2-b]pyridin-2-yl]pyrrolidine-2,5-dione;(3R)-3-[(4-fluoro-5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]-3-[5-[2-[4-(2,2,2-trifluoroacetyl)piperazin-1-yl]-4-pyridinyl]furo[3,2-b]pyridin-2-yl]pyrrolidine-2,5-dione is COc1ccc2c(c1F)C(=O)N(C[C@@]1(c3cc4nc(-c5ccc(N)nc5)ccc4o3)CC(=O)NC1=O)C2.COc1ccc2c(c1F)C(=O)N(C[C@@]1(c3cc4nc(-c5ccnc(N6CCN(C(=O)C(F)(F)F)CC6)c5)ccc4o3)CC(=O)NC1=O)C2.COc1ccc2c(c1F)C(=O)N(C[C@@]1(c3cc4nc(-c5ccnc(N6CCNCC6)c5)ccc4o3)CC(=O)NC1=O)C2.COc1ccc2c(c1F)C(=O)N(C[C@@]1(c3cc4nc(N(C5=CCN=C5)C5CCN(C)CC5)ccc4o3)CC(=O)NC1=O)C2.

What is the InChIKey of (3R)-3-[5-(6-amino-3-pyridinyl)furo[3,2-b]pyridin-2-yl]-3-[(4-fluoro-5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]pyrrolidine-2,5-dione;(3R)-3-[(4-fluoro-5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]-3-[5-[(1-methylpiperidin-4-yl)-(2H-pyrrol-4-yl)amino]furo[3,2-b]pyridin-2-yl]pyrrolidine-2,5-dione;(3R)-3-[(4-fluoro-5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]-3-[5-(2-piperazin-1-yl-4-pyridinyl)furo[3,2-b]pyridin-2-yl]pyrrolidine-2,5-dione;(3R)-3-[(4-fluoro-5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]-3-[5-[2-[4-(2,2,2-trifluoroacetyl)piperazin-1-yl]-4-pyridinyl]furo[3,2-b]pyridin-2-yl]pyrrolidine-2,5-dione?

The InChIKey is MYTHWIWRQSXRFP-UBBDELJFSA-N. The full InChI is InChI=1S/C32H26F4N6O6.C31H31FN6O5.C30H27FN6O5.C26H20FN5O5/c1-47-22-4-2-18-15-42(28(44)26(18)27(22)33)16-31(14-25(43)39-29(31)45)23-13-20-21(48-23)5-3-19(38-20)17-6-7-37-24(12-17)40-8-10-41(11-9-40)30(46)32(34,35)36;1-36-11-8-19(9-12-36)38(20-7-10-33-15-20)25-6-5-22-21(34-25)13-24(43-22)31(14-26(39)35-30(31)41)17-37-16-18-3-4-23(42-2)28(32)27(18)29(37)40;1-41-22-4-2-18-15-37(28(39)26(18)27(22)31)16-30(14-25(38)35-29(30)40)23-13-20-21(42-23)5-3-19(34-20)17-6-7-33-24(12-17)36-10-8-32-9-11-36;1-36-18-5-2-14-11-32(24(34)22(14)23(18)27)12-26(9-21(33)31-25(26)35)19-8-16-17(37-19)6-4-15(30-16)13-3-7-20(28)29-10-13/h2-7,12-13H,8-11,14-16H2,1H3,(H,39,43,45);3-7,13,15,19H,8-12,14,16-17H2,1-2H3,(H,35,39,41);2-7,12-13,32H,8-11,14-16H2,1H3,(H,35,38,40);2-8,10H,9,11-12H2,1H3,(H2,28,29)(H,31,33,35)/t2*31-;30-;26-/m1111/s1.

What are the key properties of (3R)-3-[5-(6-amino-3-pyridinyl)furo[3,2-b]pyridin-2-yl]-3-[(4-fluoro-5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]pyrrolidine-2,5-dione;(3R)-3-[(4-fluoro-5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]-3-[5-[(1-methylpiperidin-4-yl)-(2H-pyrrol-4-yl)amino]furo[3,2-b]pyridin-2-yl]pyrrolidine-2,5-dione;(3R)-3-[(4-fluoro-5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]-3-[5-(2-piperazin-1-yl-4-pyridinyl)furo[3,2-b]pyridin-2-yl]pyrrolidine-2,5-dione;(3R)-3-[(4-fluoro-5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]-3-[5-[2-[4-(2,2,2-trifluoroacetyl)piperazin-1-yl]-4-pyridinyl]furo[3,2-b]pyridin-2-yl]pyrrolidine-2,5-dione?

(3R)-3-[5-(6-amino-3-pyridinyl)furo[3,2-b]pyridin-2-yl]-3-[(4-fluoro-5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]pyrrolidine-2,5-dione;(3R)-3-[(4-fluoro-5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]-3-[5-[(1-methylpiperidin-4-yl)-(2H-pyrrol-4-yl)amino]furo[3,2-b]pyridin-2-yl]pyrrolidine-2,5-dione;(3R)-3-[(4-fluoro-5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]-3-[5-(2-piperazin-1-yl-4-pyridinyl)furo[3,2-b]pyridin-2-yl]pyrrolidine-2,5-dione;(3R)-3-[(4-fluoro-5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]-3-[5-[2-[4-(2,2,2-trifluoroacetyl)piperazin-1-yl]-4-pyridinyl]furo[3,2-b]pyridin-2-yl]pyrrolidine-2,5-dione has a molecular weight of 2325.27 g/mol, XLogP of 10.92, 24 rotatable bonds, 6 hydrogen bond donors, and 35 hydrogen bond acceptors.

Where does this data come from?

All data for (3R)-3-[5-(6-amino-3-pyridinyl)furo[3,2-b]pyridin-2-yl]-3-[(4-fluoro-5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]pyrrolidine-2,5-dione;(3R)-3-[(4-fluoro-5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]-3-[5-[(1-methylpiperidin-4-yl)-(2H-pyrrol-4-yl)amino]furo[3,2-b]pyridin-2-yl]pyrrolidine-2,5-dione;(3R)-3-[(4-fluoro-5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]-3-[5-(2-piperazin-1-yl-4-pyridinyl)furo[3,2-b]pyridin-2-yl]pyrrolidine-2,5-dione;(3R)-3-[(4-fluoro-5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]-3-[5-[2-[4-(2,2,2-trifluoroacetyl)piperazin-1-yl]-4-pyridinyl]furo[3,2-b]pyridin-2-yl]pyrrolidine-2,5-dione is sourced from PubChem (CID 159710349), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).